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1

Boeckl, Katharina, Hannah Striebinger, Nikolaus Kneidinger, et al. "Monitoring the Cytomegalovirus-specific cellular immunity in lung transplant recipients: A comparative analysis of two assay systems." Journal of Immunology 196, no. 1_Supplement (2016): 140.29. http://dx.doi.org/10.4049/jimmunol.196.supp.140.29.

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Abstract Objective Monitoring the cellular immunity for Cytomegalovirus (CMV) in organ transplant recipients is a promising tool to support prevention strategies for posttransplant CMV infection or reactivation. Commercially available in vitro test systems differ substantially in their capacity to stimulate subpopulations of T-lymphocytes. We compared two assays for CMV immune monitoring in respect of their clinical practicability and significance. Methods Blood samples of 30 lung transplant recipients (LuTRs) were examined before transplantation and over a period of six months afterwards with
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Richter, Anne, Michaela Niemöller, Inken Verwohl, et al. "Rapid and Semi-Automated Screening of Multiple Samples for Antigen-Specific T Lymphocytes." Blood 120, no. 21 (2012): 4839. http://dx.doi.org/10.1182/blood.v120.21.4839.4839.

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Abstract Abstract 4839 Functional characterizations of T lymphocytes are performed to gain understanding on their contribution in certain immunological situations, to monitor the course of diseases, and to track therapeutic interventions. Meanwhile the flow cytometric analysis of antigen-specific T cells examined for intracellular cytokine production and expression of activation markers after a short-term in vitro antigenic challenge is a well-established method for research applications. Despite the advantages of this approach to qualify samples on a single cell level and by multiple paramete
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Kouklakis, Georgios, Petros Zezos, Nikolaos Liratzopoulos, et al. "Endoscopic Treatment of a Gastrocutaneous Fistula Using the Over-The-Scope-Clip System: A Case Report." Diagnostic and Therapeutic Endoscopy 2011 (May 29, 2011): 1–5. http://dx.doi.org/10.1155/2011/384143.

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The over-the-scope-clip (OTSC; Ovesco Endoscopy GmbH, Tuebingen, Germany) system is a newly designed method for the mechanical compression of large areas in the gastrointestinal tract. So far, indications for OTSC application are hemostasis of primary or postinterventional bleeding, closure of iatrogenic full-thickness or covered perforations. Recently closure of gastrointestinal tract fistulas using this device has been described. A 44-year-old man developed a gastrocutaneous fistula after surgical treatment for a perforated gastric ulcer. We describe the successful endoscopic closure of the
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Pacini, G., S. Paolino, F. Goegan, et al. "THU0359 GENDER IMPACT ON LOWER URINARY TRACT INVOLVEMENT IN SYSTEMIC SCLEROSIS PATIENTS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 410.1–411. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4701.

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Background:Lower urinary tract symptoms (LUTS) are an underdiagnosed but frequent manifestation in systemic sclerosis (SSc) [1]. LUTS pathogenesis in SSc is undetermined, mainly involving dysautonomia, fibrosis and a possible antibody-mediated damage [2]. Divergently from general population, female sex and advanced age are not reported to significantly impact LUTS in SSc [2].Objectives:To evaluate the potential influence of gender and hormone-related factors in LUTS prevalence and severity among SSc patients (Pts).Methods:A population of 42 SSc Pts and 50 age- and sex-matched healthy subjects
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Johansen, Ib-Rune, Glenn Terje Lines, Atle Honne, and Tonje Midtgaard. "Calibration of an FT-IR Spectrometer for Ambient Air Monitoring Using PLS." Applied Spectroscopy 51, no. 10 (1997): 1540–46. http://dx.doi.org/10.1366/0003702971939073.

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The objective of this work has been to develop a robust calibration method for simultaneous multigas detection with a Fourier transform infrared (FT-IR) system. Calibration models for the identification and quantification of 23 gases in the presence of high concentrations of background gases such as water vapor, carbon dioxide, and methane have been obtained for an FT-IR instrument with 0.7-cm−1 resolution. The calibration models have been tested on a breadboard instrument for trace gas measurement in manned space missions. The results show that FT-IR combined with multivariate methods such as
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Hutchinson, Harry. "To Get to the Other Side." Mechanical Engineering 128, no. 04 (2006): 40–42. http://dx.doi.org/10.1115/1.2006-apr-4.

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This paper discusses engineering design ideas employed by P. Wirzius Heavy Assembly GmbH of Hinden, Germany, to transport heavy loads across states. In order to find a safe way to cross its bridges, Wirzius enlisted a specialist in getting heavy objects safely to their destinations, Greiner Vehicle Technology, an engineering company based in Neuenstein, Germany. Greiner says it designs systems for transporting large machinery by road or rail. Working with Wirzius, the Greiner company devised a plan to transfer some of the extraordinary vehicle weight to a temporary track system that would chan
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Adamu, L. M., N. G. Obaje, A. A. Sidi, A. K. Aweda, and H. M. Liman. "Geochemical Evidence for the Origin of the Daranna Manganese Deposit, Kebbi State, Nigeria." Nigerian Journal of Basic and Applied Sciences 29, no. 2 (2022): 30–45. http://dx.doi.org/10.4314/njbas.v29i2.4.

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Inorganic and organic geochemical and geostatistical studies of manganese ore deposits exposed at Daranna, near Kaoje have been carried out with the aim of characterizing and delineating the origin of the manganese ore deposits. Data were obtained from field observations and chemical analyses of 12 ore samples. Major and trace elements and organic geochemical analyses were conducted with Energy Dispersion X-ray Fluorescence Spectrometer and Rock-Eval pyrolysis method at Geo-data GmbH Garbsen, Germany. Results of the Major and trace elements, total organic carbon content abundances and the corr
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Zimmermann, Welf, and Stefan Kuss. "New Composite Construction Method with STEEL/UHPFRC Constructing Railway Bridges." Solid State Phenomena 292 (June 2019): 242–48. http://dx.doi.org/10.4028/www.scientific.net/ssp.292.242.

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In Austria last years sequenced according modern technology successfully bridges were made from UHPC or UHPFRC [1], [2], [3]. A couple of well-done examples of these bridges I presented on the occasion of Prof. Sparowitz birthday publication in 2017 [2]. Recently in Austria another example of a railway bridge consisting innovative material UHPFRC - created as a composite construction - was projected by ZKP ZT GmbH by order of Austrian Railway Company ÖBB. Innovative and new is the application of Ultra-High Performance Concrete in combination with Steel S355J2+N creating a composite action in
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Leicht, Lisa, Tilmann Wendel, and Maximilian Wolf. "Implementierung von agiler Führung in multinationalen Konzernen: Empirische Erkenntnisse aus der Halbleiterbranche." Leadership, Education, Personality: An Interdisciplinary Journal 2, no. 1 (2020): 41–51. http://dx.doi.org/10.1365/s42681-020-00012-3.

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Abstract This paper provides empirical insights and practical implications for the implementation process of agile leadership in multinational firms. Building on Häußler’s and Fischer’s Trafo-model our research shows that the dimensions “culture” and “leadership” have been important dimensions for the Advantest Europe GmbH in 2017 to boost the implementation of agile leadership. Concerning the dimension “culture” the most important insight was that agile leadership is more than agile methods such as Scrum or Kanban. Concerning the dimension “leadership” our results show for example that a lack
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Dressler, Valderi. "Professor Valderi Dressler, a great admirer of young Brazilian scientists, kindly granted BrJAC an interview." Brazilian Journal of Analytical Chemistry 10, no. 38 (2022): 6–10. http://dx.doi.org/10.30744/brjac.2179-3425.interview.dressler.

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Valderi Luiz Dressler holds a chemistry degree (1992) and a master’s in chemistry (1994) from the Federal University of Santa Maria (UFSM), RS, Brazil, a PhD in chemistry (1999) from the Federal University of Santa Catarina, SC, Brazil and post-doctorates from Forschungszentrum Julich GmbH, Germany (2007 and 2010). Currently, he is a full professor and coordinator of the industrial chemistry and bachelor's chemistry degree courses at the UFSM. Dr. Dressler’s research activities mainly include trace analysis and environmental chemistry, involving the techniques of atomic absorption spectrometry
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Egido, J. M. F., J. R. Maestre, and M. Y. Pena Izquierdo. "Consideraciones sobre elaislamiento en exudados vaginales de Streptococcus morbillorum." Revista da Sociedade Brasileira de Medicina Tropical 28, no. 2 (1995): 117–22. http://dx.doi.org/10.1590/s0037-86821995000200006.

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De el estúdio de 195 exudados vaginales enviados por el Servicio de Ginecologia de este hospital, durante el período 1988-1990, hemos seleccionado aquellos en los que el cultivo fue positivo para estreptococos, 58 (30%) de los cuales 26 (44.8%) correspondia a Streptococcus morbillorum, 9 (15.5%) a Gardnerella vaginalis, 5 (8.6%) a Enterococcus faecalis-durans, y a Streptococcus agalactiae, 3 (5.1%) a Streptococcus mitis y Streptococcus mitis, 2 (3-4%) a Streptococcus bovis y Streptococcus cremoris y 1 (1.7%) a Streptococcus salivarius, Streptococcus equinus y Strptococcus sanguis II respectiva
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Schinderling, A., A. Bohlen, T. Seefeld, and H. Falldorf. "In-process monitoring of track geometry as a control approach for laser metal deposition." IOP Conference Series: Materials Science and Engineering 1296, no. 1 (2023): 012010. http://dx.doi.org/10.1088/1757-899x/1296/1/012010.

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Abstract Laser metal deposition (LMD) is an additive manufacturing process, which is used to generate large parts or for reconditioning machine components. During the process the welding tracks are affected by complex dynamic temperature-time curves that results in geometric deviations, which limits the build-up process. Therefore, complex structures are more difficult to manufacture with constant parameters. The present work describes an in-process monitoring system and first approaches of a control concept for LMD processes. It is set up using a newly developed laser triangulation sensor fro
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YOSHIMURA, TOSHIO, DESH DEEPAK, and HITOSHI TAKAGI. "Track/vehicle system identification by a revised group method of data handling (GMDH)." International Journal of Systems Science 16, no. 1 (1985): 131–44. http://dx.doi.org/10.1080/00207728508926660.

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Bredthauer, Andre, Manuel Kopfmueller, Michael Gruber, et al. "Therapeutic Anticoagulation with Argatroban and Heparins Reduces Granulocyte Migration: Possible Impact on ECLS-Therapy?" Cardiovascular Therapeutics 2020 (April 25, 2020): 1–10. http://dx.doi.org/10.1155/2020/9783630.

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Introduction. Anticoagulants such as argatroban and heparins (low-molecular-weight and unfractionated) play an immense role in preventing thromboembolic complications in clinical practice. Nevertheless, they can also have a negative effect on the immune system. This study is aimed at investigating the influence of these substances on polymorphonuclear neutrophils (PMNs), whose nonspecific defense mechanisms can promote thrombogenesis. Methods. Blood samples from 30 healthy volunteers were investigated, whereby PMNs were isolated by density gradient centrifugation and incubated with 0.8 μg/mL o
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Gruber-Dorninger, Christiane, Manuela Killinger, Andreas Höbartner-Gußl, et al. "Enzymatic Degradation of Zearalenone in the Gastrointestinal Tract of Pigs, Chickens, and Rainbow Trout." Toxins 15, no. 1 (2023): 48. http://dx.doi.org/10.3390/toxins15010048.

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The estrogenic mycotoxin zearalenone (ZEN) is a common contaminant of animal feed. Effective strategies for the inactivation of ZEN in feed are required. The ZEN-degrading enzyme zearalenone hydrolase ZenA (EC 3.1.1.-, commercial name ZENzyme®, BIOMIN Holding GmbH, Getzersdorf, Austria) converts ZEN to hydrolyzed ZEN (HZEN), thereby enabling a strong reduction in estrogenicity. In this study, we investigated the efficacy of ZenA added to feed to degrade ZEN in the gastrointestinal tract of three monogastric animal species, i.e., pigs, chickens, and rainbow trout. For each species, groups of an
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Ozkan, Esra Cifci, Gulay Dumanli Gok, Nazli Ece Ordueri, and Tugba Elgun. "Cytotoxicity evaluation of different clear aligner materials using MTT analysis." Australasian Orthodontic Journal 38, no. 2 (2022): 348–54. http://dx.doi.org/10.2478/aoj-2022-0034.

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Abstract Backround: The in vitro cytotoxic effects of six different clear aligner materials were evaluated using the MTT analysis. Methods: The clear aligner material samples [Duran (ScheuDental GmbH, Iserlohn, Germany), Zendura-Flx (Bay Materials LLC, Fremont, CA, USA), Taglus (Laxmi Dental Export Pvt. Ltd, Mumbai, India), Smart Track (Align Technology, San Jose, CA, USA), Zendura (Bay Materials LLC, Fremont, CA, USA), Essix C + (Essix® (Raintree Essix, Inc., 4001 Division St, Metairie, LA-USA)] were initially kept in a saline solution in airtight test tubes for 8 weeks at 37°C. According to
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Kalil, Mohammad Nur Amin, Wardah Yusof, Naveed Ahmed, et al. "Performance Validation of COVID-19 Self-Conduct Buccal and Nasal Swabs RTK-Antigen Diagnostic Kit." Diagnostics 11, no. 12 (2021): 2245. http://dx.doi.org/10.3390/diagnostics11122245.

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The antigen rapid diagnostic test (Ag-RDT) is an immunodiagnostic test that detects the presence of viral proteins (antigens) expressed by the COVID-19 virus in a sample from a patient’s respiratory tract. This study focused on evaluating the performance of self-conduct buccal and nasal swabs RTK-antigen test compared to nasopharyngeal swab RTK-based COVID-19 diagnostic assays, Panbio™ COVID-19 Ag Rapid Test Device (Nasopharyngeal) (Abbott Rapid Diagnostics Jena GmbH, Jena, Germany) used in hospitals for first-line screening. The sensitivity and specificity of the paired RTK-Ag test in detecti
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Е.В., Глушко, Марданлы С.Г. та Королева Т.А. "ИССЛЕДОВАНИЕ СРАВНИТЕЛЬНОЙ ФАРМАКОКИНЕТИКИ И БИОЭКВИВАЛЕНТНОСТИ ПРЕПАРАТОВ УРСОДЕЗОКСИХОЛЕВОЙ КИСЛОТЫ". Вопросы обеспечения качества лекарственных средств, № 4(34) (9 грудня 2021): 44–50. http://dx.doi.org/10.34907/jpqai.2021.66.67.007.

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Одним из наиболее распространенных заболеваний человечества является желчнокаменная болезнь (ЖКБ). В настоящее время существует только одно вещество с доказанным действием на различные звенья билиарного литогенеза – урсодезоксихолевая кислота (УДХК). Область ее терапевтического применения весьма обширна и включает разные заболевания печени и желчевыводящих путей. Чтобы подтвердить эффективность и безопасность регистрируемого ЗАО «ЭКОлаб» препарата «Урсолаб», основным действующим веществом которого является урсодезоксихолевая кислота, было проведено исследование сравнительной фармакокинетики и
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Yohannes, Alexander, Judith Knievel, Jonas Lange, et al. "VacStent as an Innovative Approach in the Treatment of Anastomotic Insufficiencies and Leakages in the Gastrointestinal Tract—Review and Outlook." Life 14, no. 7 (2024): 821. http://dx.doi.org/10.3390/life14070821.

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Anastomotic insufficiencies are severe complications of abdominal surgery, often leading to prolonged hospitalization, serious tissue inflammation, and even sepsis, along with the need for recurrent surgery. Current non-surgical treatments such as self-expanding metal stents (SEMSs) and endoscopic vacuum therapy (EVT) have limitations, including stent migration or perforation. This review evaluates the effectiveness of the VacStent GITM (Möller Medical GmbH, Fulda, Germany), a novel medical device combining SEMS and negative-pressure wound therapy in treating gastrointestinal leaks. Data were
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Bocos-Bintintan, Victor, George-Bogdan Ghira, Mircea Anton, Aurel-Vasile Martiniuc, and Ileana-Andreea Ratiu. "Sensing Precursors of Illegal Drugs—Rapid Detection of Acetic Anhydride Vapors at Trace Levels Using Photoionization Detection and Ion Mobility Spectrometry." Molecules 25, no. 8 (2020): 1852. http://dx.doi.org/10.3390/molecules25081852.

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Sensitive real-time detection of vapors produced by the precursors, reagents and solvents used in the illegal drugs manufacture represents a priority nowadays. Acetic anhydride (AA) is the key chemical used as acetylation agent in producing the illegal drugs heroin and methaqualone. This study was directed towards quick detection and quantification of AA in air, using two fast and very sensitive analytical techniques: photoionization detection (PID) and ion mobility spectrometry (IMS). Results obtained indicated that both PID and IMS can sense AA at ultra-trace levels in air, but while PID pro
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Vakhrushev, Ya M., A. P. Lukashevich, and E. V. Suchkova. "ASSOCIATION OF INTESTINAL BACTERIAL OVERGROWTH AND DISEASES OF HEPATOBIARY TRACT." Russian Archives of Internal Medicine 9, no. 1 (2019): 64–69. http://dx.doi.org/10.20514/2226-6704-2019-9-1-64-69.

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The aim. Find out the nature of the changes of the hepatobiliary system in patients with intestinal bacterial overgrowth and study the possible mechanisms of their association.Materials and methods. 148 patients with intestinal bacterial overgrowth and intestinal dysbiosis were examined. The level of total cholesterol, cholestasis and cytolysis markers was determined in the blood using the analyzer «Labsystems» (Finland). Intestinal bacterial overgrowth syndrome was assessed using a hydrogen breath test with lactulose on the LactophaH2 apparatus of AMA (St. Petersburg). Intestinal dysbiosis wa
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Karrer, Sigrid, Petra Unger, Michael Gruber, et al. "In Vitro Safety Study on the Use of Cold Atmospheric Plasma in the Upper Respiratory Tract." Cells 13, no. 17 (2024): 1411. http://dx.doi.org/10.3390/cells13171411.

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Cold atmospheric plasma (CAP) devices generate reactive oxygen and nitrogen species, have antimicrobial and antiviral properties, but also affect the molecular and cellular mechanisms of eukaryotic cells. The aim of this study is to investigate CAP treatment in the upper respiratory tract (URT) to reduce the incidence of ventilator-associated bacterial pneumonia (especially superinfections with multi-resistant pathogens) or viral infections (e.g., COVID-19). For this purpose, the surface-microdischarge-based plasma intensive care (PIC) device was developed by terraplasma medical GmbH. This stu
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Nixdorf, U., D. Steinhage, U. Meyer, et al. "The newly developed airborne radio-echo sounding system of the AWI as a glaciological tool." Annals of Glaciology 29 (1999): 231–38. http://dx.doi.org/10.3189/172756499781821346.

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AbstractSince 1994 the Alfred Wegener Institute (AWI) has operated an airborne radio-echo sounding system for remote-sensing studies of the polar ice caps in Antarctica and in Greenland. It is used to map ice thicknesses and internal layernigs of glaciers, ice sheets and ice shelves, and is capable of penetrating ice thicknesses of up to 4 km. The system was designed and built by AWI in cooperation with Aerodata Flugmeßtechnik GmbH, Technische Umversitat Hamburg-Harburg and the Deutsches Zentrum fur Luft- und Raumfahrt e.V. The system uses state-of-the-art techniques, and results in high verti
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Manz, Georg, and Esther Booltink. "Validation Study of a HistaSure™ ELISAFast Track for the Determination of Histamine in Fish Samples." Journal of AOAC INTERNATIONAL 97, no. 6 (2014): 1601–14. http://dx.doi.org/10.5740/jaoacint.14-067.

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Abstract LDN Labor Diagnostika Nord GmbH & Co. KG has developed an ELISA for the rapid semiquantitative or quantitative determination of histamine in different kinds of fish samples. Fresh/frozen tuna, canned tuna, fresh/frozen mahi mahi, canned sardines, and fish meal were used to validate the method under the requirements of the AOAC Research Institute Performance Tested MethodsSM Program. The results all fell within the defined acceptance criteria. Linearity was given throughout the 0–300 ppm measuring range. Cross reactivity to similarly structured food spoilage indicators (tyramine an
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Reichold, Leonardo Zamorano, Michael Gruber, Petra Unger, et al. "Cellular Response of Immune Cells in the Upper Respiratory Tract After Treatment with Cold Atmospheric Plasma In Vitro." International Journal of Molecular Sciences 26, no. 1 (2024): 255. https://doi.org/10.3390/ijms26010255.

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Cold atmospheric plasma (CAP) has antimicrobial properties and is also known to stimulate the immune system. These properties could be useful for the development of a novel therapeutic or preventive strategy against respiratory infections in the upper respiratory tract (URT) such as ventilator-associated pneumonia (VAP) without inducing an immune overreaction. This study investigated the cellular responses of polymorphonuclear neutrophils (PMNs) after exposure to CAP in a three-dimensional (3D) model of the URT. In vitro experiments were conducted using PMNs isolated from human blood to assess
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Radžiūnas, Gintautas, Inga Kildušienė, Juozas Stanaitis, Arnoldas Krasauskas, and Narimantas Evaldas Samalavičius. "Endoskopinis virškinamojo trakto fistulių, perforacijų ir anastomozių nepakankamumo gydymas naudojant OTSC kabutę (OVESCO)." Lietuvos chirurgija 13, no. 2 (2014): 98–103. http://dx.doi.org/10.15388/lietchirur.2014.2.3085.

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Įvadas / tikslasOTSC (Over-The-Scope Clip, Ovesco Endoscopy GmbH, Tuebingen, Vokietija) – tai naujas endoskopinis virškinamojo trakto vientisumo atkūrimo būdas, naudojant endoskopinę kabutę, stipriau ir plačiau suspaudžiančią defekto kraštus, palyginti su įprastine per endoskopo kanalą uždedama kabute. OTSC naudojama su lanksčiais endoskopais šiais atvejais: 1) ūminiam kraujavimui stabdyti, 2) kiauriniam virškinamojo trakto defektui užverti, 3) audiniams suspausti ir suartinti, 4) endoskopinių ir chirurginių intervencijų komplikacijoms gydyti. Publikacijos tikslas – retrospektyvioji OTSC naudo
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Radžiūnas, Gintautas, Inga Kildušienė, Juozas Stanaitis, Arnoldas Krasauskas, and Narimantas Evaldas Samalavičius. "Endoskopinis virškinamojo trakto fistulių, perforacijų ir anastomozių nepakankamumo gydymas naudojant OTSC kabutę (OVESCO)." Lietuvos chirurgija 13, no. 2 (2014): 98–103. http://dx.doi.org/10.15388/lietchirur.2014.3085.

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Įvadas / tikslasOTSC (Over-The-Scope Clip, Ovesco Endoscopy GmbH, Tuebingen, Vokietija) – tai naujas endoskopinis virškinamojo trakto vientisumo atkūrimo būdas, naudojant endoskopinę kabutę, stipriau ir plačiau suspaudžiančią defekto kraštus, palyginti su įprastine per endoskopo kanalą uždedama kabute. OTSC naudojama su lanksčiais endoskopais šiais atvejais: 1) ūminiam kraujavimui stabdyti, 2) kiauriniam virškinamojo trakto defektui užverti, 3) audiniams suspausti ir suartinti, 4) endoskopinių ir chirurginių intervencijų komplikacijoms gydyti. Publikacijos tikslas – retrospektyvioji OTSC naudo
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Kostiuchenko-Faifor, O. S., I. V. Gunas, A. A. Glushak, L. V. Babych, and R. V. Skoruk. "Peculiarities of correlations of upper respiratory tract cephalometric parameters in Ukrainian young men and young women regardless of face type." Reports of Morphology 29, no. 1 (2023): 15–23. http://dx.doi.org/10.31393/morphology-journal-2023-29(1)-03.

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The study of the parameters of the upper respiratory tract has become one of the leading directions of medical research, due to the connection of this structure with the occurrence and course of many diseases of both childhood and adulthood. The study of normative indicators of this structure and its relationship with craniometric indicators should be the first step before further research of samples with pathologies. The purpose of the study is to establish correlations of cephalometric parameters of the upper respiratory tract in Ukrainian young men and young women with an orthognathic bite,
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Bocos-Bintintan, Victor, and Ileana Andreea Ratiu. "Hunting for Toxic Industrial Chemicals: Real-Time Detection of Carbon Disulfide Traces by Means of Ion Mobility Spectrometry." Toxics 8, no. 4 (2020): 121. http://dx.doi.org/10.3390/toxics8040121.

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Sensitive real-time detection of vapors produced by toxic industrial chemicals (TICs) represents a stringent priority nowadays. Carbon disulfide (CS2) is such a chemical, being widely used in manufacturing synthetic textile fibers and as a solvent. CS2 is simultaneously a very reactive, highly flammable, irritant, corrosive, and highly toxic compound, affecting the central nervous system, cardiovascular system, eyes, kidneys, liver, skin, and reproductive system. This study was directed towards quick detection and quantification of CS2 in air, using time-of-flight ion mobility spectrometry (IM
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Kostiuchenko-Faifor, O. S. "Correlations of cephalometric parameters of the upper respiratory tract in Ukrainian young men and young women with a wide face type." Reports of Vinnytsia National Medical University 27, no. 2 (2023): 183–89. http://dx.doi.org/10.31393/reports-vnmedical-2023-27(2)-01.

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Annotation. Changes in the size of the upper respiratory tract can lead to the emergence or aggravation, complications of already existing pathologies. In this regard, there is a need to study their sizes both in normal and pathological conditions. Cephalometric analysis is one of the important tools that allows you to assess the location of the structures of the upper respiratory tract and their parameters. The purpose of the study is to establish the peculiarities of correlations between cephalometric parameters of the upper respiratory tract in Ukrainian young men and young women with an or
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Bzdil, J., O. Holy, and J. Toporcak. "Gram-negative aerobic and microaerophilic microorganisms isolated from pathological processes and lesions of horses." Veterinární Medicína 63, No. 2 (2018): 55–62. http://dx.doi.org/10.17221/117/2017-vetmed.

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The pathogenicity of bacterial strains isolated from pathological processes and lesions of horses, strategies for their treatment and the choice of appropriate antimicrobials are frequently a challenging problem for private veterinarians who seek help in our laboratory. Therefore, the aim of this study was to map genera and species of Gram-negative aerobic and microaerophilic microorganisms isolated from pathological processes in horses and to identify the most effective antimicrobial agents for therapy based on antibiotic susceptibility. Between 2009 and 2014 a total of 449 clinical samples (
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Ruffilli, Alberto, Francesco Traina, Isabella Corneti, et al. "Temperature-Controlled Continuous Cold Flow Device after Total Knee Arthroplasty: A Randomized Controlled Trial Study." Journal of Knee Surgery 30, no. 07 (2016): 675–81. http://dx.doi.org/10.1055/s-0036-1593874.

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Total knee arthroplasty (TKA) is a widely accepted and successful procedure for end-stage arthritis. Nevertheless, fast-track may be compromised by many factors, such as pain, edema, and blood loss. Cryotherapy has been advocated as a safe and effective strategy to improve the postoperative results, acting on pain, edema, and blood loss. This study is a prospective randomized controlled study, involving 50 patients after primary TKA. A power analysis was performed preoperatively. Twenty-four patients were addressed to a postoperative treatment with a continuous cold flow device (Hilotherm, Hil
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Castilhos, Raphael Machado de, José Augusto dos Santos, Marina Coutinho Augustin, et al. "Minimal prevalence of Huntington’s disease in the South of Brazil and instability of the expanded CAG tract during intergenerational transmissions." Genetics and Molecular Biology 42, no. 2 (2019): 329–36. http://dx.doi.org/10.1590/1678-4685-gmb-2018-0032.

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Hellqvist, Eva, Frida Holm, Cayla N. Mason, et al. "CD44 Monoclonal Antibody-Enhanced Clearance Of Chronic Myeloid Leukemia Stem Cells From The Malignant Niche." Blood 122, no. 21 (2013): 858. http://dx.doi.org/10.1182/blood.v122.21.858.858.

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Abstract Introduction Leukemia stem cells (LSC) in chronic myeloid leukemia (CML) are important in disease progression and relapse. Conventional therapy with tyrosine kinase inhibitors (TKIs), although very effective at reducing bulk CML cells, frequently fail to eliminate LSC residing in the protective bone marrow niche. Thus, there is an unmet need for combination therapy that simultaneously targets bulk disease and eliminates LSC in order to prevent disease progression and relapse. Stem cell niches are often rich in hyaluronic acid. CD44, the main receptor for hyaluronic acid, and some of i
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Kosztyła-Hojna, Bożena, Anna Łobaczuk-Sitnik, Maciej Zdrojkowski, et al. "Analysis of voice quality parameters in patients with vestibular voice." Otolaryngologia Polska 73, no. 3 (2019): 11–15. http://dx.doi.org/10.5604/01.3001.0012.8373.

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Abstract Vestibular voice includes participation of larynx structures which are absent in physiological process. Vestibular phonation may be desired when vocal folds are damaged as in paralytic dysphonia, or undesired in marginal hyperfunction. Vestibular voice may result from psychogenic dysphonia – phononeurosis. The aim of the study is perceptive evaluation of vestibular voice, objective larynx visualization, acoustic and aerodynamic examination. The study included 40 patients: 20 with vestibular voice, 20 with euphonic voice. Voice quality has been evaluated using perceptual GRBAS scale. E
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Tsykalov, A. N., V. A. Kravchenko, B. A. Sotnikov, and A. L. Kravchenko. "SUNFLOWER YIELD DEPENDING ON THE APPLICATION OF MICRONUTRIENTS." AGRO-INDUSTRIAL TECHNOLOGIES OF THE CENTRAL RUSSIA 1, no. 27 (2023): 115–21. http://dx.doi.org/10.24888/2541-7835-2023-27-115-121.

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The article presents the results of field experiments on the use of micro fertilizers on sunflower. The object of the study was a hybrid of sunflower Fausto from the company "Strube D&S GMBH". Field experiments were carried out with micro fertilizers of the German company "Lebozol", the Russian "Polydon Agro" and the Lithuanian "Acoustic Biotechnologies (brand Humic Land"). Leaf fertilizing with micronutrients and their treatment of sunflower seeds and their combination were studied. As studies have shown, the variant with the use of micronutrients for seed dressing against the background
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La Patilaiya, Hairudin. "Health Education For Adolescents On The Prevention Of Sexually Transmitted Diseases (STDs)." International Journal Of Community Service 2, no. 3 (2022): 384–87. http://dx.doi.org/10.51601/ijcs.v2i3.128.

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Sexually transmitted diseases or STDs for short are diseases caused by unhealthy sexual relations. STDs are usually experienced by teenagers, adults, and the elderly due to deviant behavior such as free sex, anal sex, oral sex, or because of direct contact with sufferers through the genital tract, skin touch, vaginal fluids, sperm fluid and sexual intercourse that is not use condoms and other sexual safety devices. Factors that influence adolescent behavior are personal experience, the influence of others, cultural influences, mass media, educational institutions, religion and emotional factor
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Dhanak, Parul, Neha Sharma, and Ashish Sharma. "Role of serum copper and lipid profile in cardiovascular diseases patients of Southern Rajasthan." International Journal of Research in Medical Sciences 7, no. 11 (2019): 4249. http://dx.doi.org/10.18203/2320-6012.ijrms20194583.

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Background: It is clear that deficiencies of some trace elements cause marked alterations in lipid and lipoprotein metabolism. The mechanisms of their effects are not completely obvious and inspite of intense research, the role of these microelements need further elucidation. Thus, the objective of this study is to evaluate the correlations of serum concentrations of trace elements including copper with lipid profile parameters of adult men in Southern Rajasthan.Methods: Present study was conducted in Cardiology and Biochemistry Department in GMCH, Udaipur during the year 2019. A total of 150
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Wollenhaupt, J., H. Strothmeyer, M. Fiene, S. Morys, C. Bach, and J. Roemmler-Zehrer. "FRI0365 REAL-WORLD EFFECTIVENESS AND SAFETY OF APREMILAST IN A LARGE COHORT OF GERMAN PATIENTS WITH PSORIATIC ARTHRITIS: 1-YEAR ANALYSIS OF AN ONGOING MULTICENTER, PROSPECTIVE, NON-INTERVENTIONAL STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 780.1–780. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2924.

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Background:Apremilast (APR) has been studied extensively in phase III randomized, controlled trials. However, real-world information is limited on the effectiveness and safety of APR in patients with psoriatic arthritis (PsA).Objectives:To assess the effectiveness and safety of APR in a large cohort of patients with active PsA from routine clinical practice settings in Germany.Methods:In this multicenter, prospective, non-interventional study, the primary endpoint was the proportion of patients reaching ≥1 point (≥20%) improvement from baseline (BL) in the Physician’s Global Assessment of Dise
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Crane-Godreau, Mardi A., та Charles R. Wira. "CCL20/Macrophage Inflammatory Protein 3α and Tumor Necrosis Factor Alpha Production by Primary Uterine Epithelial Cells in Response to Treatment with Lipopolysaccharide or Pam3Cys". Infection and Immunity 73, № 1 (2005): 476–84. http://dx.doi.org/10.1128/iai.73.1.476-484.2005.

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ABSTRACT Having previously shown that CCL20/macrophage inflammatory protein 3α and tumor necrosis factor alpha (TNF-α) are released by polarized primary rat uterine epithelial cells (UEC) in response to Escherichia coli but not to Lactobacillus rhamnosus, we sought to determine if epithelial cells are responsive to pathogen-associated molecular patterns (PAMP), including lipopolysaccharide (LPS), lipoteichoic acid (LTA), and Pam3Cys, a bacterial lipoprotein analog. Epithelial cells were grown to confluence on Nunc cell culture inserts prior to apical treatment with PAMPs. In response to LPS, L
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Engelhardt, Hans-Joachim, Tilman Fischer, Hannes Räuschel, and Frank Klingner. "BGzEro – backfilling measures with low CO2 footprint." Safety of Nuclear Waste Disposal 2 (September 6, 2023): 171. http://dx.doi.org/10.5194/sand-2-171-2023.

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Abstract. In Germany, the Federal Company for Radioactive Waste Disposal (BGE) is responsible for the construction and operation of deep, geological repositories. BGE operates the Asse II mine and the Konrad and Morsleben repositories. Initially, these mines were excavated to extract raw materials. As a result, they have large void volumes on multiple levels. The stability of the unfilled cavities is limited in time so that backfilling measures are required for stabilisation. However, there are many requirements to consider when selecting backfill materials. BGE aims at making its locations cl
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Adeyinka, Daniel Adedayo, Pammla Margaret Petrucka, Elon Warnow Isaac, and Nazeem Muhajarine. "Changing patterns of gender inequities in childhood mortalities during the Sustainable Development Goals era in Nigeria: findings from an artificial neural network analysis." BMJ Open 11, no. 1 (2021): e040302. http://dx.doi.org/10.1136/bmjopen-2020-040302.

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ObjectivesIn line with the child survival and gender equality targets of Sustainable Development Goals (SDG) 3 and 5, we aimed to: (1) estimate the age and sex-specific mortality trends in child-related SDG indicators (ie, neonatal mortality rate (NMR) and under-five mortality rate (U5MR)) over the 1960s–2017 period, and (2) estimate the expected annual reduction rates needed to achieve the SDG-3 targets by projecting rates from 2018 to 2030.DesignGroup method of data handling-type artificial neural network (GMDH-type ANN) time series.MethodsThis study used an artificial intelligence time seri
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Hamilton-Craig, Christian, Daniel Stäeb, Aiman Al Najjar, et al. "7-Tesla Functional Cardiovascular MR Using Vectorcardiographic Triggering—Overcoming the Magnetohydrodynamic Effect." Tomography 7, no. 3 (2021): 323–32. http://dx.doi.org/10.3390/tomography7030029.

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Objective: Ultra-high-field B0 ≥ 7 tesla (7T) cardiovascular magnetic resonance (CMR) offers increased resolution. However, electrocardiogram (ECG) gating is impacted by the magneto-hydrodynamic effect distorting the ECG trace. We explored the technical feasibility of a 7T magnetic resonance scanner using an ECG trigger learning algorithm to quantitatively assess cardiac volumes and vascular flow. Methods: 7T scans were performed on 10 healthy volunteers on a whole-body research MRI MR scanner (Siemens Healthineers, Erlangen, Germany) with 8 channel Tx/32 channels Rx cardiac coils (MRI Tools G
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Souareba, Tchinfanbe, Jean-Claude Doumnang, Parfait Rondouba, Mianpereum Tarkodjiel, and Yaya Mahmout. "Evaluation de la contamination par les métaux lourds (Al, Fe, Mn, Ni, Zn, Cr, Cd et Pb) des sédiments du bassin du lac Léré, Mayo-Kebbi Ouest, Tchad." International Journal of Biological and Chemical Sciences 18, no. 2 (2024): 723–36. http://dx.doi.org/10.4314/ijbcs.v18i2.31.

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Les activités anthropiques sont à l’origine des émissions des éléments métalliques qui contribuent à la dégradation de la qualité des sédiments des milieux lacustres. Dans le but de caractériser l’état de la qualité des sédiments du bassin du lac Léré, site centré entre 9,37° de longitude Nord et 14,10° de latitude Est, Département du Mayo-Kebbi Ouest et de constituer une base des données relatives aux métaux lourds, cette présente étude visait à évaluer l’état de contamination des sédiments de ce bassin par les métaux lourds à savoir l’aluminium (Al), le fer (Fe), le manganèse (Mn), le nickel
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Bodnar, Liubov, Dmytro Lytkin, and Nataliia Polovko. "Conducting biological tests in the development of self-emulsifying drug delivery systems with simvastatin." ScienceRise: Pharmaceutical Science, no. 6(46) (December 31, 2023): 64–69. http://dx.doi.org/10.15587/2519-4852.2023.295450.

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The aim of the study was to compare the hypolipidemic activity of the developed self-emulsifying drug delivery systems with simvastatin with reference samples of the substance and the finished drug product of industrial production. Materials and methods. The substance of simvastatin (India, s. DK40-2005021, 99.09 %, introduced into the composition of self-emulsifying compositions based on castor oil (Ukraine), polyethylene glycol 40 hydrogenated castor oil (India), Tween 80 (Ukraine), glycerol monostearate (Gustav Heess GmbH, Germany) or polyethylene glycol 100 stearate (ERCA, Italy). Referenc
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Carpenter, Chris. "AI Approach Advances Predictive Precision in CO2 Minimum Miscibility Pressure." Journal of Petroleum Technology 77, no. 01 (2025): 59–62. https://doi.org/10.2118/0125-0059-jpt.

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_ This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 219101, “Advancing Predictive Precision in CO2 Minimum Miscibility Pressure: An Interpretable AI Approach for CO2 EOR and CCUS Applications,” by Fahimeh Hadavimoghaddam, Ufa State Petroleum Technological University and Northeast Petroleum University; Peyman Pourafshary, SPE, Nazarbayev University, and Alexei Rozhenko, Plekhanov Russian University of Economics, et al. The paper has not been peer reviewed. _ The study described in the complete paper develops an explainable data-driven method using
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Carrasco, C., R. Romar, J. Marcos, M. Aviles, and P. Coy. "290 ENZYMATIC ACTIVITY LEVEL OF SOME GLYCOSIDASES IN BOVINE OVIDUCTAL FLUID AT DIFFERENT STAGES OF THE ESTROUS CYCLE." Reproduction, Fertility and Development 19, no. 1 (2007): 260. http://dx.doi.org/10.1071/rdv19n1ab290.

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Carbohydrates play a key role in different reproductive events such as the sperm–oviductal cell interaction and sperm–oocyte recognition. In this way, α-d-mannosyl (Amari et al. 2006 Mol. Reprod. Dev. 59, 221–226) and α-2,3-sialic acid (Velasquez et al. 2006 Mol. Reprod. Dev. in press) residues contained in the zona pellucida have been identified as sperm receptors in bovine oocytes. The glycosidases, enzymes that remove carbohydrates, could play an important role in the reproductive tract, modulating decisive physiological events mediated by carbohydrates. However, the enzymatic activity leve
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Darius, Sabine, Susanne Voigt-Zimmermann, Katarina Berkhauer, and Irina Böckelmann. "Belastbarkeit der Stimme von Erzieherinnen in Abhängigkeit vom Dysphonie-Schweregrad-Index." Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie 75, no. 3 (2025): 136–47. https://doi.org/10.1007/s40664-024-00563-y.

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Zusammenfassung Berufsbedingter Umgebungslärm in Kindertagesstätten kann sich negativ auf die Stimme der Erzieherin auswirken. Eine kranke Stimme ist durch eine eingeschränkte stimmliche Belastbarkeit gekennzeichnet, die wiederum die Berufsausübung beeinträchtigt. Der überwiegende Teil der frühpädagogischen Fachkräfte ist weiblich und hinsichtlich berufsbedingter Stimmstörungen besonders risikobehaftet. Ziel der Studie ist es zu untersuchen, ob sich Erzieherinnen mit einem auffälligen Dysphonie-Schweregrad-Index (DSI) hinsichtlich des Auftretens von Stimmbeschwerden und der stimmlichen Belastb
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Janakwade, Shivhar K., Sadbhavana Pandit, and Neeraj Dhawan. "Magnesium sulphate nebulization in acute bronchiolitis in infants: a randomized controlled trial." International Journal of Contemporary Pediatrics 8, no. 6 (2021): 1048. http://dx.doi.org/10.18203/2349-3291.ijcp20212046.

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Background: Acute bronchiolitis is a disorder of the lower respiratory tract that occurs mostly in between 1 month to 24 months. There are limited numbers of studies on magnesium sulphate nebulization in acute bronchiolitis. There is a desperate need for a standard treatment which can reduce the morbidity and mortality in acute bronchiolitis. The goal was to study the efficacy of magnesium sulphate nebulization in infants with acute bronchiolitis.Methods: It was a prospective open labelled randomized controlled study. Children in age group of 2-12 months admitted with clinical diagnosis of acu
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Purwanti, Anik Sri, Sumarno Sumarno, Bambang Rahardjo, Sri Winasih, and Sri Poeranto. "Kombinasi Glucomannan Hydrolysates (Gmh) Dan Antibiotik Metronidazole Berpengaruh Terhadap Kadar Sitokin Il-23 Pada Bacterial Vaginosis Wanita Usia Subur." Care : Jurnal Ilmiah Ilmu Kesehatan 7, no. 1 (2019): 9. http://dx.doi.org/10.33366/jc.v7i1.1105.

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Woman’s reproductive tract often has problems, especially in women of childbearing age. One of them is Bacterial Vaginosis is a clinical condition that occurs a lot. BV infection is a polymicrobial infection caused by a decrease in the amount of Lactobaclilus with anaerobic bacteria that increases excessively. Alternative treatment for BV is given by using the results hydrolysates of konjac plant extracted in dosage forms Glucomannan Hydrolysates (GMH) containing glucose and mannose prebiotic which can support the growth development of Lactobacillus in the vaginal mucosa. This study was to det
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