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1

Carossino, Mariano. "CELLULAR AND MOLECULAR BASIS OF EQUINE ARTERITIS VIRUS PERSISTENT INFECTION IN THE STALLION REPRODUCTIVE TRACT: CHARACTERIZATION OF LOCAL HOST-PATHOGEN INTERACTIONS MEDIATING LONG-TERM VIRAL PERSISTENCE." UKnowledge, 2018. https://uknowledge.uky.edu/gluck_etds/35.

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Equine arteritis virus (EAV) has a global impact on the equine industry being the causative agent of equine viral arteritis (EVA), a reproductive, respiratory, and systemic disease of equids. A distinctive feature of EAV infection is that it establishes long-term persistent infection in the reproductive tract of stallions and is continuously shed in the semen (carrier state). Recent studies showed that long-term persistence is associated with a specific allele of the CXCL16 gene (CXCL16S). However, the cellular and molecular mechanisms underlying the establishment and maintenance of persistent
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Tiwari, Ashish. "ROLE OF VIRAL AND HOST FACTORS IN INFLUENZA VIRUS MEDIATED INHIBITION OF INTERLEUKIN-23." UKnowledge, 2014. http://uknowledge.uky.edu/gluck_etds/19.

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Influenza virus is one of the major respiratory pathogens of humans as well as animals, including equines. There is an increasing evidence that bacterial infections are the most common cause of the death during influenza. In horses also, secondary bacterial pneumonia can lead to death, and surviving horses may take up to six months for the complete recovery resulting in heavy economic loss to the equine industry. Interleukin (IL)-23 mediated innate immune response has been shown to protect the host from various respiratory bacterial infections. However, studies to investigate the role of host
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Thomas, Sarah Elizabeth. "A Prevalence Study of Southeast Origin Sale Barn Beef Cattle, Comingled in Warren County, Kentucky, Persistently Infected with Bovine Viral Diarrhea Virus, including the Effects of Season and Body Weight." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1070.

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Bovine viral diarrhea (BVD) is an economically important disease of cattle. Calves persistently infected (PI) with the bovine viral diarrhea virus (BVDV) are a powerful agent for spread of the virus. A total of 24,423 southeast origin beef cattle comingled at three Warren County, Kentucky locations were tested from November 2007 to June 2010 for PI BVDV. A total of 97 head tested positive for PI BVDV, giving an average overall prevalence of 0.397%. Calves tested were subdivided into categories for additional calculations of dependence. A total of 8,910 were categorized by weight range upon te
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Singleton, Michael David. "Nonlinear Hierarchical Models for Longitudinal Experimental Infection Studies." UKnowledge, 2015. http://uknowledge.uky.edu/epb_etds/7.

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Experimental infection (EI) studies, involving the intentional inoculation of animal or human subjects with an infectious agent under controlled conditions, have a long history in infectious disease research. Longitudinal infection response data often arise in EI studies designed to demonstrate vaccine efficacy, explore disease etiology, pathogenesis and transmission, or understand the host immune response to infection. Viral loads, antibody titers, symptom scores and body temperature are a few of the outcome variables commonly studied. Longitudinal EI data are inherently nonlinear, often with
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Welsh, Michael D. "Effects of bovine viral diarrhoea virus/mucosal disease virus on the functional properties of bovine mononuclear cells." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282343.

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Langel, Stephanie Mary Neal. "Defining the Gut-Mammary Gland-Secretory IgA Axis in Porcine Epidemic Diarrhea Virus Infected Gilts and its Impact on Lactogenic Immune Protection of Neonatal Suckling Piglets." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1542041868304033.

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SILVA, Débora Scopel e. "Avaliação da atividade do peptídeo antimicrobiano P34 frente a vírus patogênicos aos animais domésticos." Universidade Federal de Pelotas, 2013. http://repositorio.ufpel.edu.br/handle/ri/2499.

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Made available in DSpace on 2014-08-20T14:37:53Z (GMT). No. of bitstreams: 1 dissertacao_debora_scopel.pdf: 765310 bytes, checksum: dc0bea20bd4a62c37e4145ef858b7894 (MD5) Previous issue date: 2013-02-27<br>The development and use of drugs with the ability to prevent or strike an infection are indispensable for human and animal health. However, the antiviral drug arsenal is still small and has serious use restrictions, like small activity range, limited therapeutic usage and several degrees of cytotoxicity. The objective of this work was to evaluate the antiviral activity of an antibacterial
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Grissett, Gretchen Phoebe. "Systematic review of cattle responses to viral and bacterial bovine respiratory disease pathogens and effect of high ambient temperaure on viral replication and serology to an intranasal modified-live (bovine rhinotracheitis-parainfluenza-3) viral vaccine in beef cattle." Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/18169.

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Master of Veterinary Biomedical Sciences<br>Department of Clinical Sciences<br>Bradley White<br>Objective- To compare serologic response and viral replication following intranasal administration of a modified-live bovine rhinotracheitis (IBR) parainfluenza-3 (PI-3) vaccine in high (32°C) and moderate (21°C) ambient temperatures. Animals- 28 heifers (mean body weight, 206.8 kg) Procedures- Heifers randomly allocated to treatment groups: High Ambient Temperature (HAT, n=10): received vaccine, housed outdoors, Moderate Ambient Temperature (MAT, n=10): received vaccine, housed indoors, High Ambi
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Lu, Zhengchun. "DEVELOPMENT OF MOLECULAR DIAGNOSTIC ASSAYS FOR EQUINE RESPIRATORY VIRUSES AND ANALYSIS OF THE ROLE OF EQUINE ARTERITIS VIRUS ENVELOPE PROTEINS IN THE EARLY EVENTS OF VIRUS ENTRY." UKnowledge, 2012. http://uknowledge.uky.edu/gluck_etds/3.

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There is an urgent need for detection of viral respiratory pathogens to identify the causal agent(s) involved and to prevent the spread of related diseases. The first part of this dissertation focuses on development, optimization and validation of Real-time reverse transcription polymerase chain reaction (rRT-PCR) assays for the detection of several common equine viral pathogens: equine arteritis virus (EAV), equine influenza virus and equine rhinitis viruses A and B. Emphasis of the second part of this dissertation is on studying the role of EAV envelope proteins in virus attachment and entry
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Antoniassi, Nadia Aline Bobbi. "Aspectos clínicos e patológicos da infecção pelo vírus da língua azul em ovinos no estado do Rio Grande do Sul." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/25163.

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Língua Azul (LA) é uma doença causada pelo Vírus da Língua Azul (VLA) e transmitida por vetores do gênero Culicoides. Estudos sorológicos tem demonstrado a ampla presença do vírus no Brasil, entretanto, informações clínicas da LA na América do Sul são limitadas. Este trabalho descreve alterações clínico-patológicas em ovinos acometidos pela LA no Estado do Rio Grande do Sul, Brasil. Em dois surtos, em propriedades distintas, 15 ovinos apresentaram como principais sinais clínicos hipertermia, apatia, aumento de volume da face e região submandibular, dificuldade de deglutição com regurgitação, s
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Niederwerder, Megan C. "Clinical disease and host response of nursery pigs following challenge with emerging and re-emerging swine viruses." Diss., Kansas State University, 2015. http://hdl.handle.net/2097/20491.

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Doctor of Philosophy<br>Diagnostic Medicine/Pathobiology<br>Raymond R. R. Rowland<br>Emerging viral diseases cause significant and widespread economic losses to U.S. swine production. Over the last 25 years, porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2) and porcine epidemic diarrhea virus (PEDV) have emerged or re-emerged, costing the industry billions through increased mortality and clinical or subclinical reductions in growth. Nursery pigs are greatly affected by these viruses due to high susceptibility to primary and secondary infections aft
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Silva, Marcia Cristina da. "Neuropatologia da cinomose canina." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4037.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Canine distemper is one of the most prevalent viral diseases of dogs. Several cases are diagnosed in a daily basis in private practices and veterinary hospitals around the country. Most cases of neurological manifestation of canine distemper are fatal and the diagnosis confirmation by histopathology is often necessary. Canine distemper encephalitis is the main cause of death or reason for euthanasia in dogs necropsied at the Laboratório de Patologia Veterinária (LPV) of the Universidade Federal de Santa Maria (UFSM). Consequently t
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13

Inkelmann, Maria Andréia. "EPIDEMIOLOGIA, SINAIS CLÍNICOS, LESÕES MACRO E MICROSCÓPICAS, E IMUNOISTOQUÍMICA DA HEPATITE INFECCIOSA CANINA." Universidade Federal de Santa Maria, 2008. http://repositorio.ufsm.br/handle/1/10007.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This dissertation consists of an investigation on infectious canine hepatitis (IHC) and resulted in two scientific papers which are placed in the final part of this dissertation. The necropsy reports of 5,361 dogs necropsied over a 43-year period (1964-2006) were reviewed in search for cases of infectious canine hepatitis (ICH). Sixty two (1.2%) cases of the disease were found. Epidemiological, clinical and anatomopathogical data of these 62 cases are presented in the first paper. The second paper presents an immunoistochemistry (I
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14

Silva, Mariana Sá e. "IDENTIFICAÇÃO MOLECULAR DE HERPESVÍRUS BOVINO TIPOS 1 E 5." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4040.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Bovine herpesvirus types 1 and 5 (BoHV-1, BoHV-5) are genetically and antigenic related viruses and have been associated with important economic losses to the cattle industry. The aim of this Thesis was to perform the molecular identification of BoHV-1 and BoHV-5 isolates. The first part describes the identification of 40 herpesviruses isolated from different clinical specimens and syndromes in central-southern Brazil, Argentina and Uruguay (1987 2006). The differentiation between BoHV-1 and BoHV-5 was performed by examining the
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Rissi, Daniel Ricardo. "Epidemiologia, sinais clínicos e distribuição das lesões encefálicas em bovinos afetados por meningoencefalite por herpesvírus bovino-5 (BoHV-5)." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/10249.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Seven outbreaks and an isolated case of meningoencephalitis caused by bovine herpesvirus-5 (BoHV-5) in cattle from Rio Grande do Sul, Brazil, occurring in 2002-2004 are described. From a total population at risk of 1,359 cattle, 54 1-18-month-old calves from both sexes and several breeds were affected and 50 died spontaneously or were euthanatized while moribund. The highest frequency of cases were in recently weaned calves or calves submitted to other stressing factors. General rates of morbidity, mortality and lethality were re
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Picton, Rebecca Anne. "Serologic survey of llamas in Oregon for antibodies to viral diseases of livestock." Thesis, 1993. http://hdl.handle.net/1957/36598.

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Serums from 270 llamas representing 21 farms throughout Oregon were obtained and assayed for antibody levels against viruses of livestock. These viral diseases included: bovine viral diarrhea (BVD), bovine herpesvirus 1 (BHV-1), parainfluenza-3 (PI-3), bovine respiratory syncytial virus (BRSV), bovine adenovirus species 3 (BA3), equine herpesvirus 1 (EHV-1), equine adenovirus (EA), equine influenza, subtypes 1 and 2 (EI-1, EI-2), equine viral arteritis (EVA), ovine progressive pneumonia (OPP), bluetongue (BT), vesicular stomatitis, New Jersey strain and Indiana strain (VSV-NJ, VSV-IN), and lla
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17

Corvelo, João Paulo Valadão. "Prevalência do vírus da diarreia viral bovina (BVDV) em vacas leiteiras nas ilhas das Flores e do Corvo (Açores)." Master's thesis, 2016. http://hdl.handle.net/10437/8244.

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Orientação: João Ribeiro Lima<br>As ilhas das Flores e do Corvo pertencem ao grupo ocidental do arquipélago dos Açores. Existem cerca de 7700 bovinos distribuídos por 372 explorações, das quais, 30 são explorações leiteiras. Neste levantamento, todos os bovinos das explorações leiteiras foram testados para a presença de anticorpos contra a Doença Viral Bovina (BVD) e para a presença de vírus da Doença Viral Bovina (BVDV). O rastreio foi realizado com amostras individuais de soro utilizando o ensaio de imunoabsorção enzimática, teste de anticorpos ELISA (kit comercial ‘IDEXX BVDV total AbTest’)
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Santos, Telmo Fernandes dos. "Ensaio Clínico da Vacina Pcv-Mhyo: um estudo contemporâneo." Master's thesis, 2017. http://hdl.handle.net/10437/8396.

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Orientação: Sofia Van Harten ; co-orientação: Pedro Silvério Miguel Lopes<br>O agente etiológico da circovirose é um vírus de pequenas dimensões, ao qual se deu o nome de Porcine circovirus (PCV). O PCV é considerado um vírus ubiquitário, que causa doença exclusivamente em suínos e já foi isolado em todos os continentes. O objectivo do ensaio foi avaliar a segurança e a eficácia de uma única vacinação de leitões às três semanas de idade, com PCV-Mhyo (MSD), em comparação com a vacinação standard (Vacinas Stellamune e Porcilis PCV em separado) da exploração em questão, para a prevenção de
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