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1

Robins, H. I., D. Rushing, M. Kutz, et al. "Phase I clinical trial of melphalan and 41.8 degrees C whole-body hyperthermia in cancer patients." Journal of Clinical Oncology 15, no. 1 (1997): 158–64. http://dx.doi.org/10.1200/jco.1997.15.1.158.

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PURPOSE To evaluate the biologic interactions and toxicities of melphalan (L-PAM) combined with 41.8 degrees C whole-body hyperthermia (WBH) for 60 minutes. PATIENTS AND METHODS Sixteen patients with refractory cancer were treated (May 1992 to May 1995) with WBH alone during week 1) thereafter patients were randomized to receive either L-PAM alone on week 2 and L-PAM plus WBH on week 5, or the reverse sequence. Patients who demonstrated clinical improvement received WBH plus L-PAM monthly. Dose levels of L-PAM were 10 mg/m2 (n = 3), 15 mg/m2 (n = 3), 17.5 mg/m2 (n = 6), and 20 mg/m2 (n = 4). L
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Robins, H. I., J. D. Cohen, C. L. Schmitt, et al. "Phase I clinical trial of carboplatin and 41.8 degrees C whole-body hyperthermia in cancer patients." Journal of Clinical Oncology 11, no. 9 (1993): 1787–94. http://dx.doi.org/10.1200/jco.1993.11.9.1787.

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PURPOSE To evaluate the biologic interactions and toxicities of carboplatin combined with 41.8 degrees C whole-body hyperthermia (WBH) for 60 minutes in a phase I clinical trial. PATIENTS AND METHODS Thirty assessable patients with cancer refractory to conventional therapy were treated. During induction therapy, patients received WBH alone in week 1, WBH plus carboplatin in week 2, and carboplatin alone in week 5. Carboplatin dose was escalated (three patients per group) as follows: 100, 150, 200, 250, 300, 350, 400, 480, and 575 mg/m2; three additional patients were entered at 480 mg/m2. Carb
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Borloo, Noor, Anne Smits, Liesbeth Thewissen, Pieter Annaert, and Karel Allegaert. "Creatinine Trends and Patterns in Neonates Undergoing Whole Body Hypothermia: A Systematic Review." Children 8, no. 6 (2021): 475. http://dx.doi.org/10.3390/children8060475.

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Many neonates undergoing whole body hypothermia (WBH) following moderate to severe perinatal asphyxia may also suffer from renal impairment. While recent data suggest WBH-related reno-protection, differences in serum creatinine (Scr) patterns to reference patterns were not yet reported. We therefore aimed to document Scr trends and patterns in asphyxiated neonates undergoing WBH and compared these to centiles from a reference Scr data set of non-asphyxiated (near)term neonates. Using a systematic review strategy, reports on Scr trends (mean ± SD, median or interquartile range) were collected (
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Krnjajic, Davor, Dustin R. Allen, Cory L. Butts, and David M. Keller. "Carotid baroreflex control of heart rate is enhanced, while control of mean arterial pressure is preserved during whole body heat stress in young healthy men." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 311, no. 4 (2016): R735—R741. http://dx.doi.org/10.1152/ajpregu.00152.2016.

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Whole body heat stress (WBH) results in numerous cardiovascular alterations that ultimately reduce orthostatic tolerance. While impaired carotid baroreflex (CBR) function during WBH has been reported as a potential reason for this decrement, study design considerations may limit interpretation of previous findings. We sought to test the hypothesis that CBR function is unaltered during WBH. CBR function was assessed in 10 healthy male subjects (age: 26 ± 3; height: 185 ± 7 cm; weight: 82 ± 10 kg; BMI: 24 ± 3 kg/m2; means ± SD) using 5-s trials of neck pressure (+45, +30, and +15 Torr) and neck
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Lord, Alexander J., and Bruce Torff. "Teachers’ Beliefs about Web-Based Homework in Mathematics: Effects of Level of Student Achievement and Level of Course." Journal of Computers in Mathematics and Science Teaching 40, no. 1 (2021): 5–28. https://doi.org/10.70725/196961lociqv.

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With use of web-based homework systems (WBH) increasing in mathematics classrooms, a study was conducted in which 236 secondary mathematics teachers completed a survey assessing the extent to which their beliefs on the effectiveness of WBH varied according to level of student achievement and level of course. Results indicate that teachers judged WBH to be significantly more effective for lower-achieving students and for students enrolled in lower-level courses. These results suggest that increased use of WBH has potential to mitigate achievement gaps in mathematics by supporting the performanc
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Sheppard, Stephanie Rosenbloom, Sameer Desale, and Kabir Abubakar. "Respiratory and Hemodynamic Changes in Neonates with Hypoxic–Ischemic Encephalopathy during and after Whole-Body Hypothermia." American Journal of Perinatology 38, no. 01 (2019): 037–43. http://dx.doi.org/10.1055/s-0039-1694730.

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Abstract Objective This study aimed to determine the degree to which whole-body hypothermia (WBH) impacts hemodynamic and respiratory status during hypothermia and the subsequent rewarming period in neonates with hypoxic–ischemic encephalopathy (HIE). Study Design This is a retrospective study reviewing the medical records of infants treated with WBH. Data including oxygenation index (OI), ventilator efficiency index (VEI), fraction of inspired oxygen (FiO2), blood lactate level, heart rate (HR), and mean blood pressure (MBP) were collected from defined time points from the beginning, middle,
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Liu, Rui, Min Wang, and Jin-Ao Duan. "Antipyretic and Antioxidant Activities of the Aqueous Extract of Cornu Bubali (Water Buffalo Horn)." American Journal of Chinese Medicine 38, no. 02 (2010): 293–306. http://dx.doi.org/10.1142/s0192415x10007853.

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Cornu Bubali (water buffalo horn, WBH) is an animal-derived product which is widely used in Traditional Chinese Medicine (TCM) for dispelling heat, relieving convulsions and cooling blood. The purpose of this study was to investigate the antipyretic activity of WBH aqueous extract and its potential mechanism. Two hyperthermia models, yeast-induced (infectious) and skimmed milk-induced (noninfectious) hyperthermia were employed to evaluate the antipyretic effect and the results showed that rectal temperature of hyperthermia animals was decreased significantly after oral administration of WBH ex
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Cui, Jian, Zhaohui Gao, Cheryl Blaha, Jonathan Carter Luck, Kristen Brandt, and Lawrence I. Sinoway. "Moderate whole body heating attenuates the exercise pressor reflex responses in older humans." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320, no. 5 (2021): R757—R769. http://dx.doi.org/10.1152/ajpregu.00232.2020.

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Prior reports show that whole body heat stress attenuates the pressor response to exercise in young healthy subjects. The effects of moderate whole body heating (WBH; e.g., increase in internal temperature Tcore of ∼0.4°C–0.5°C) or limb heating on sympathetic and cardiovascular responses to exercise in older healthy humans remain unclear. We examined the muscle sympathetic nerve activity (MSNA), mean arterial blood pressure (MAP), and heart rate (HR) in 14 older (62 ± 2 yr) healthy subjects during fatiguing isometric handgrip exercise and postexercise circulatory occlusion (PECO). The protocol
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Khanlarian, Cynthia J., and Rahul Singh. "An Exploratory Study of the Online Learning Environment." Issues in Accounting Education 29, no. 1 (2013): 117–47. http://dx.doi.org/10.2308/iace-50614.

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ABSTRACT Web-based homework (WBH) is an increasingly important phenomenon. There is little research about its character, the nature of its impact on student performance, and how that impact evolves over an academic term. The primary research questions addressed in this study are: What relevant factors in a WBH learning environment impact students' performance? And how does the impact of these factors change over the course of an academic term? This paper examines and identifies significant factors in a WBH learning environment and how they impact student performance. We studied over 300 studen
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Langhorst, Jost, Anna K. Koch, Christina Kehm, Özlem Öznur, Harald Engler, and Winfried Häuser. "Mild Water-Filtered Infrared-A Whole-Body Hyperthermia Reduces Pain in Patients with Fibromyalgia Syndrome—A Randomized Sham-Controlled Trial." Journal of Clinical Medicine 12, no. 8 (2023): 2945. http://dx.doi.org/10.3390/jcm12082945.

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The challenging treatment situation of patients with fibromyalgia syndrome (FMS) requires additional therapy options. The effects of water-filtered infrared-A whole-body hyperthermia (WBH) versus sham hyperthermia on pain intensity were investigated in an outpatient setting within a two-armed randomized sham-controlled trial. n = 41 participants aged between 18 and 70 years with a medically confirmed diagnosis of FMS were randomized to WBH (intervention; n = 21) or sham hyperthermia (control; n = 20). Six treatments with mild water-filtered infrared-A WBH over a period of three weeks with at l
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Dominic J, Sturm, Kunz Christoph, Peteinatos Gerassimos, and Gerhards Roland. "Do cover crop sowing date and fertilization affect field weed suppression?" Plant, Soil and Environment 63, No. 2 (2017): 82–88. http://dx.doi.org/10.17221/1/2017-pse.

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The weed suppressive ability of oilseed radish (Raphanus sativus var. oleiformis Pers.) cover crop is attributed to high competitiveness for resources and biochemical effects on weeds. The oilseed radish cover crop was sown in five treatments plus an untreated control over a period of five weeks before and three weeks after winter wheat harvest. Additionally, fertilization effects on oilseed radish biomass and weed suppression were measured. The highest biomass of the cover crop was observed 12 weeks after harvest (WAH) when the oilseed radish was sown one week after harvest (1 WAH) (2015) and
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Atanackovic, Djordje, Kristina Pollok, Christiane Faltz, et al. "Patients with solid tumors treated with high-temperature whole body hyperthermia show a redistribution of naive/memory T-cell subtypes." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 290, no. 3 (2006): R585—R594. http://dx.doi.org/10.1152/ajpregu.00014.2005.

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An activation of the immune system might contribute to the therapeutic effect of whole body hyperthermia (WBH) in cancer patients. We explored immune and endocrine responses in patients undergoing high-temperature WBH. Identical parameters were investigated in a separate group of healthy volunteers undergoing physical exercise to rule out effects of sympathetic activation. Lymphocyte subpopulations, lymphocytic expression of a range of adhesion molecules, and serum concentrations of a variety of hormones and cytokines were assessed in cancer patients undergoing high-temperature (60 min at 41.0
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Izquierdo-Villalba, David, Silvia Bonoli, Massimo Dotti, Alberto Sesana, Yetli Rosas-Guevara, and Daniele Spinoso. "From galactic nuclei to the halo outskirts: tracing supermassive black holes across cosmic history and environments." Monthly Notices of the Royal Astronomical Society 495, no. 4 (2020): 4681–706. http://dx.doi.org/10.1093/mnras/staa1399.

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ABSTRACT We study the mass assembly and spin evolution of supermassive black holes (BHs) across cosmic time as well as the impact of gravitational recoil on the population of nuclear and wandering BHs (wBHs) by using the semi-analytical model L-Galaxies run on top of Millennium merger trees. We track spin changes that BHs experience during both coalescence events and gas accretion phases. For the latter, we assume that spin changes are coupled with the bulge assembly. This assumption leads to predictions for the median spin values of z = 0 BHs that depend on whether they are hosted by pseudo-b
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Peck, Gregory M., David Zakalik, and Michael G. Brown. "Cider Apple Harvest Maturity and Preharvest Drop Can Be Effectively Managed with Aminoethoxyvinylglycine, 1-Naphthaleneacetic Acid, and Ethephon." HortTechnology 35, no. 4 (2025): 524–32. https://doi.org/10.21273/horttech05627-25.

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Certain European high-tannin cider apple (Malus ×domestica Borkh.) cultivars used for commercial production of craft hard cider (fermented apple juice) are known to have severe preharvest fruit drop, as well as asynchronous ripening. A 2-year (2018 and 2019) study at two commercial orchards in Wayne County, NY, USA, examined the effects on drop and ripeness of applying three plant growth regulators—aminoethoxyvinylglycine (AVG), ethephon (ETH), and 1-naphthaleneacetic acid (NAA)—on eight different cider apple cultivars. The treatments included i) untreated control, ii) ETH applied 1 week befor
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Brandhorst, H., M. Olbrich, A. Neumann, H. Jahr, and D. Brandhorst. "Effect of Pretransplant Preconditioning by Whole Body Hyperthermia on Islet Graft Survival." Cell Transplantation 16, no. 7 (2007): 707–15. http://dx.doi.org/10.3727/000000007783465163.

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Previous observations in heat-shocked pig islets revealed the ambivalent character of the stress response simultaneously inducing processes of protection and apoptosis. To clarify whether the proapoptotic character of the stress response is reduced in heat-exposed islets still embedded in their native environment, hyperthermia was performed in the present study either as whole body hyperthermia (WBH) prior to pancreas resection or as in vitro heat shock (HS) after isolation. HS (42°C/45 min) was induced in donors 12 h before isolation (WBH, n = 32) or in freshly isolated islets prior to 12 h o
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Zalewski, D., A. Nobis, E. Dąbrowska, and N. Waszkiewicz. "The use of light, temperature and pressure in the treatment of depression." European Psychiatry 64, S1 (2021): S740. http://dx.doi.org/10.1192/j.eurpsy.2021.1961.

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IntroductionClimate and weather have a great influence on the prevalence of depressive disorders. Selected physical parameters for instance light, temperature and pressure can be used to treat mood disorders.ObjectivesThe present mini-review aims at approximating the mechanisms by which selected, strictly controlled physical parameters in particular light, temperature, and oxygen pressure can help in the treatment of depression and determine their potential effectiveness.MethodsRelevant literature was identified by searching the PubMed/Medline database, by combining the search strategy of free
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Schupp, James R., and Duane W. Greene. "Effect of Aminoethoxyvinylglycine (AVG) on Preharvest Drop, Fruit Quality, and Maturation of `McIntosh' Apples. I. Concentration and Timing of Dilute Applications of AVG." HortScience 39, no. 5 (2004): 1030–35. http://dx.doi.org/10.21273/hortsci.39.5.1030.

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To compare the effects of growth regulators on preharvest fruit drop and fruit maturity, aminoethoxyvinylglycine (AVG) was applied to `McIntosh' apple trees at 75, 150, or 225 mg·L-1, at 8, 4, or 2 weeks before harvest (WBH). These treatments were compared to NAA, daminozide, and to an untreated control. All AVG treatments and timings except 75 mg·L-1 applied 8 WBH delayed preharvest drop and fruit maturity. AVG applied at 225 mg·L-1was more effective in delaying drop and development of maturity than other rates when applied 8 or 2 WBH, but at 4 WBH, 150 mg·L-1 gave equivalent results to 225 m
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Öznur, Özlem, Christoph Schlee, Sandra Utz, and Jost Langhorst. "Investigating the Influential Factors of Mild Water-Filtered Infrared-A Whole-Body Hyperthermia for Pain Relief in Fibromyalgia: A Mixed-Methods Approach Focusing on Predictors and Patient Perspectives." Biomedicines 11, no. 11 (2023): 2949. http://dx.doi.org/10.3390/biomedicines11112949.

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Fibromyalgia syndrome (FMS) is a chronic condition characterized by chronic widespread pain, persistent fatigue, and disrupted sleep, significantly impacting well-being. Mild water-filtered infrared-A (wIRA) whole-body hyperthermia (WBH) is emerging as a promising pain management approach to FMS. Within the present randomized controlled trial (ClinicalTrials ID: NCT05135936), FMS patients underwent six sessions of mild wIRA-WBH over 3 weeks. Their pain levels were assessed at baseline and at week 12, while body core temperature and plateau phase duration were monitored during WBH. Qualitative
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Farrell, D. M., and V. S. Bishop. "Permissive role for nitric oxide in active thermoregulatory vasodilation in rabbit ear." American Journal of Physiology-Heart and Circulatory Physiology 269, no. 5 (1995): H1613—H1618. http://dx.doi.org/10.1152/ajpheart.1995.269.5.h1613.

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The present study was designed to test the hypothesis that during whole body heating (WBH), nitric oxide (NO) synthesized in the endothelium acts synergistically with an unknown neurotransmitter to elicit active vasodilation. Rabbits were instrumented for the measurement of mean arterial pressure, heart rate, and ear blood flow (EBF) (Doppler ultrasound). During WBH, either N omega-nitro-L-arginine methyl ester (L-NAME, 10-40 mg over 10-15 min, n = 6 rabbits; group 1), a NO synthase inhibitor, or saponin (30-40 mg over 10-20 min, n = 6 rabbits; group 2), a detergent that denudes the endotheliu
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Allen, Dustin R., Mu Huang, Iqra M. Parupia, Ariana R. Dubelko, Elliot M. Frohman, and Scott L. Davis. "Impaired sweating responses to a passive whole body heat stress in individuals with multiple sclerosis." Journal of Neurophysiology 118, no. 1 (2017): 7–14. http://dx.doi.org/10.1152/jn.00897.2016.

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Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS), disrupting autonomic function. The aim of this study was to test the hypothesis that individuals with MS have blunted control of thermoregulatory reflex increases in sweat rate (SR) and cutaneous vasodilation compared with controls during a passive whole body heat stress (WBH). Eighteen individuals with relapsing-remitting MS and 18 healthy controls (Con) participated in the study. Core temperature (Tcore), skin temperature, heart rate, arterial blood pressure (10-min intervals), skin blood flow (la
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Taylor, W. F., and V. S. Bishop. "A role for nitric oxide in active thermoregulatory vasodilation." American Journal of Physiology-Heart and Circulatory Physiology 264, no. 5 (1993): H1355—H1359. http://dx.doi.org/10.1152/ajpheart.1993.264.5.h1355.

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We have shown previously that an increase in ear blood flow velocity (EBF) in the conscious, chronically instrumented rabbit during whole body heating (WBH) involves active neurogenic vasodilation that is abolished by local nerve block. This study was designed to test the potential role of nitric oxide (NO) in rabbit ear neurogenic vasodilation during hyperthermia. Rabbits were instrumented for the measurement of arterial pressure, heart rate, and EBF (Doppler ultrasound). A catheter was also placed in the left lingual artery for administration of drugs to the left ear. WBH was achieved by cir
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Tuliński, Arkadiusz. "Oficerowie Biura Historycznego i Wojskowego Biura Historycznego w latach 1922–1939 (część 2)." Przegląd Historyczno-Wojskowy 21, no. 2 (2020): 161–99. http://dx.doi.org/10.32089/wbh.phw.2020.2(272).0006.

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The presented biographical collective study concerns the officers of the Historical Bureau/Military Historical Bureau (BH/WBH). It contains biographical notes on officers serving in BH/WBH in 1922–1939, preceded by a preliminary collective portrait of the officers. The biographical notes were prepared taking into account especially their age, civil education, knowledge of foreign languages, the course of military service, work in headquarters or such entities as military museums or educational institutions. The author’s intention was to concisely present both the dynamic development of the off
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Tuliński, Arkadiusz. "Oficerowie Biura Historycznego i Wojskowego Biura Historycznego w latach 1922–1939 (część 1)." Przegląd Historyczno-Wojskowy 20, no. 4 (2019): 157–89. http://dx.doi.org/10.32089/wbh.phw.2019.4(270).0005.

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The presented biographical collective study concerns the officers of the Historical Bureau/Military Historical Bureau (BH/WBH). It contains biographical notes on officers serving in BH/WBH in 1922–1939, preceded by a preliminary collective portrait of the officers. The biographical notes were prepared taking into account especially their age, civil education, knowledge of foreign languages, the course of military service, work in headquarters or such entities as military museums or educational institutions. The author’s intention was to concisely present both the dynamic development of the off
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Staal, M. A., and A. C. M. Meuwese. "Het instructieamendement: geautomatiseerd op zoek naar een nieuw fenomeen." RegelMaat 40, no. 2 (2025): 94–109. https://doi.org/10.5553/rm/0920055x2025040002002.

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Het instructieamendement: geautomatiseerd op zoek naar een nieuw fenomeen In dit artikel signaleren de auteurs een twaalftal ‘instructieamendementen’ ingediend bij de behandeling van de Wet betaalbare huur (Wbh) die de amvb-regelgever een wijzigingsopdracht van een bestaande amvb meegeven. Met behulp van een geautomatiseerde zoekmethode komen de auteurs tot de conclusie dat de specifiek bij de Wbh herkende insteek nieuw is. Zij denken dat deze amendementen een symptoom zijn van een behoefte bij de Tweede Kamer aan meer betrokkenheid bij lagere regelgeving. De bestaande procedures en wetgevings
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Henríquez-Piskulich, Patricia A., Constanza Schapheer, Nicolas J. Vereecken, and Cristian Villagra. "Agroecological Strategies to Safeguard Insect Pollinators in Biodiversity Hotspots: Chile as a Case Study." Sustainability 13, no. 12 (2021): 6728. http://dx.doi.org/10.3390/su13126728.

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Industrial agriculture (IA) has been recognized among the main drivers of biodiversity loss, climate change, and native pollinator decline. Here we summarize the known negative effects of IA on pollinator biodiversity and illustrate these problems by considering the case of Chile, a “world biodiversity hotspot” (WBH) where food exports account for a considerable share of the economy in this country. Most of Chile’s WBH area is currently being replaced by IA at a fast pace, threatening local biodiversity. We present an agroecological strategy for sustainable food production and pollinator conse
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Kurpeshev, O. K., and J. Van der Zee. "Hyperthermia in Conservative and Palliative Treatment of Oncological Patients. Part II. Whole Body Hyperthermia." MEDICAL RADIOLOGY AND RADIATION SAFETY 67, no. 2 (2022): 43–58. http://dx.doi.org/10.33266/1024-6177-2022-67-2-43-58.

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The analysis of the results of the use of whole-body hyperthermia (WBH) in patients with locally advanced, recurrent and / or metastatic tumors, which, as a rule, are radio- and chemo-resistant. Most patients were incurable, in connection with which the treatment was mainly carried out with a palliative purpose. The analysis showed that the method alone or in combination with chemo- and radiation therapy has pronounced direct and palliative effects, in some cases it provides long-term control. However, WBH can have side effects. This necessitates further improvement of the method, development
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Ogawa, Takahiro, Sven P. Hoekstra, Yoshi-Ichiro Kamijo, et al. "Serum and plasma brain-derived neurotrophic factor concentration are elevated by systemic but not local passive heating." PLOS ONE 16, no. 12 (2021): e0260775. http://dx.doi.org/10.1371/journal.pone.0260775.

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Brain-derived neurotrophic factor (BDNF) plays a key role in neuronal adaptations. While previous studies suggest that whole-body heating can elevate circulating BDNF concentration, this is not known for local heating protocols. This study investigated the acute effects of whole-body versus local passive heating on serum and plasma BDNF concentration. Using a water-perfused suit, ten recreationally active males underwent three 90 min experimental protocols: heating of the legs with upper-body cooling (LBH), whole-body heating (WBH) and a control condition (CON). Blood samples were collected be
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Mason, Ashley E., Sarah M. Fisher, Anoushka Chowdhary, et al. "Feasibility and acceptability of a Whole-Body hyperthermia (WBH) protocol." International Journal of Hyperthermia 38, no. 1 (2021): 1529–35. http://dx.doi.org/10.1080/02656736.2021.1991010.

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Zan, Ming, Zhongming Xu, Linsen Huang, and Zhifei Zhang. "A Sound Source Identification Algorithm Based on Bayesian Compressive Sensing and Equivalent Source Method." Sensors 20, no. 3 (2020): 865. http://dx.doi.org/10.3390/s20030865.

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Near-field acoustic holography (NAH) based on equivalent source method (ESM) is an effective method for identifying sound sources. Conventional ESM focuses on relatively low frequencies and cannot provide a satisfactory solution at high frequencies. So its improved method called wideband acoustic holography (WBH) has been proposed, which has high reconstruction accuracy at medium-to-high frequencies. However, it is less accurate for coherent sound sources at low frequencies. To improve the reconstruction accuracy of conventional ESM and WBH, a sound source identification algorithm based on Bay
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Hodges, Gary J., Caroline Chiu, Wojciech A. Kosiba, Kun Zhao, and John M. Johnson. "The effect of microdialysis needle trauma on cutaneous vascular responses in humans." Journal of Applied Physiology 106, no. 4 (2009): 1112–18. http://dx.doi.org/10.1152/japplphysiol.91508.2008.

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Microdialysis enables in-depth mechanistic study of the cutaneous circulation in humans. However, whether the insertion or presence of the microdialysis fiber (MDF) affects the skin circulation or its responses is unknown. We tested whether the cutaneous vascular response to whole body heating (WBH) was affected by MDF or by pretreatment with ice ( part 1) or local anesthesia (LA; part 2). Eleven subjects participated, 9 in part 1 and 8 in part 2 (5 participated in both). In both parts, four sites on the forearm were selected, providing untreated control, MDF only, ice or LA only, and combined
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Sokolnicki, Lynn A., Nicholas A. Strom, Shelly K. Roberts, Shirley A. Kingsley-Berg, Ananda Basu, and Nisha Charkoudian. "Skin blood flow and nitric oxide during body heating in type 2 diabetes mellitus." Journal of Applied Physiology 106, no. 2 (2009): 566–70. http://dx.doi.org/10.1152/japplphysiol.91289.2008.

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Individuals with type 2 diabetes mellitus (T2DM) often exhibit microvascular dysfunction that may contribute to impaired thermoregulation, but potential mechanisms remain unclear. Our goals were to quantify skin blood flow responses and nitric oxide-mediated vasodilation during body heating in individuals with T2DM compared with nondiabetic control subjects of similar age. We measured skin blood flow (laser-Doppler flowmetry) in conjunction with intradermal microdialysis of NG-nitro-l-arginine methyl ester (l-NAME; nitric oxide synthase inhibitor) or vehicle during 45–60 min of whole body heat
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Mace, Thomas A., Casey Kilpatrick, Evan Zynda, and Elizabeth Repasky. "Increased body temperature induces lymphocyte lipid raft aggregation (35.34)." Journal of Immunology 182, no. 1_Supplement (2009): 35.34. http://dx.doi.org/10.4049/jimmunol.182.supp.35.34.

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Abstract Previous recent data reveal that mild heating in vitro of CD4+ and CD8+ T cells (purified from murine splenocytes) at 39.5°C induces the aggregation of lipid rafts; approximately 70% of lymphocytes express aggregated lipid rafts compared to only 20% of cells maintained at 37oC as judged by the distribution of the lipid raft marker, fluorescently labeled GM1. Further, we found that the fluidity of the T cell plasma membrane, as measured by fluorescence anisotropy of TMA-DPH, increases when the temperature is raised from 37° to 39.5°C. Based on these in vitro results, we hypothesized th
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Wilkinson, John Ben, Peter D. Beitsch, Douglas W. Arthur, et al. "Evaluation of current consensus panel guidelines for APBI: A pooled analysis of William Beaumont Hospital and American Society of Breast Surgeons MammoSite registry trial data." Journal of Clinical Oncology 30, no. 27_suppl (2012): 145. http://dx.doi.org/10.1200/jco.2012.30.27_suppl.145.

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145 Background: To determine whether the ASTRO Consensus Panel (CP) guidelines for accelerated partial breast irradiation (APBI) are associated with significantly different outcomes in a pooled analysis from William Beaumont Hospital (WBH) and the American Society of Breast Surgeons (ASBrS) MammoSite Registry Trial. Methods: 2,127 cases of early-stage breast cancer were treated using APBI (WBH: n=678; ASBrS: n=1,449). Three forms of APBI were used at WBH (interstitial, n=221; balloon-based, n=255; or 3D-CRT, n=206) while all Registry Trial patients received balloon-based brachytherapy. Patient
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Bibus, Erhard, Manfred Frechen, Michael Kösel, and Wolfgang Rähle. "Das jungpleistozäne Lössprofil von Nussloch (SW-Wand) im Aufschluss der Heidelberger Zement AG." E&G Quaternary Science Journal 56, no. 4 (2007): 227–55. http://dx.doi.org/10.3285/eg.56.4.01.

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Abstract. At the Nussloch section located south of Heidelberg, a more recently exposed new loess wall was pedologically investigated. The profiles were investigated multidisciplinarily including grain-size spectra, organic and carbonate content, magnetic susceptibility, as well as biomorphology and malacology and infrared optically stimulated luminescence (IRSL). The lower part of the Late Pleistocene includes the subdivided Eemian paleosol and the Wuermian loess about 18 m thick. A Bt horizon, a humic-rich horizon (“Humuszone”) and several tundra gleysols (“Nassböden”) of different intensity,
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Cyr, John St, T. Kelly, and Linda M. Shecterle. "Whole Body Extracorporeal Low Flow Hyperthermia in a Canine Model." Journal of ExtraCorporeal Technology 28, no. 3 (1996): 140–46. http://dx.doi.org/10.1051/ject/1996283140.

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Whole body hyperthermia (WBH) has not gained significant clinical acceptance, though extensive experimentation since the early 1980's has revealed its potential merits in the treatment of various cancers, and currently WBH is in clinical feasibility trials for Acquired Immune Deficiency Syndrome (AIDS). Using a new device and methodology, could canines serve as an appropriate test model for this device and methodology? Five dogs underwent one treatment each or the 42°C whole body hyperthermia using a low flow veno-venous approach. All animals were kept at the desired temperature for 90 minutes
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Wissig, Sebastian. "Nachfolge mit Perspektive." wwt Wasserwirtschaft Wassertechnik 74, no. 6 (2025): 47–49. https://doi.org/10.51202/1438-5716-2025-6-047.

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Der Fachkräftemangel zeigt sich in der Wasserwirtschaft an vielen Stellen. Auch Betriebsinhaber wissen oft nicht, wer einmal ihr Lebenswerk übernehmen soll. Wie eine kluge Nachfolgeplanung dazu beitragen kann, zeigt der Verkauf der WBH Water GmbH.
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Hagedorn, W. Bryce, Jack R. Culbreth, and Craig S. Cashwell. "Addiction Counseling Accreditation: CACREP’s Role in Solidifying the Counseling Profession." Professional Counselor 2, no. 2 (2012): 124–33. http://dx.doi.org/10.15241/wbh.2.2.124.

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Evans, Sharon S., Wan-Chao Wang, Mark D. Bain, Randy Burd, Julie R. Ostberg, and Elizabeth A. Repasky. "Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules." Blood 97, no. 9 (2001): 2727–33. http://dx.doi.org/10.1182/blood.v97.9.2727.

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Abstract Fever is associated with increased survival during acute infection, although its mechanism of action is largely unknown. This study found evidence of an unexpectedly integrated mechanism by which fever-range temperatures stimulate lymphocyte homing to secondary lymphoid tissues by increasing L-selectin and α4β7 integrin–dependent adhesive interactions between circulating lymphocytes and specialized high endothelial venules (HEV). Exposure of splenic lymphocytes in vivo to fever-like whole-body hyperthermia (WBH; 39.8 ± 0.2°C for 6 hours) stimulated both L-selectin and α4β7 integrin–de
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Wang, Xiang-Yang, Julie R. Ostberg, and Elizabeth A. Repasky. "Effect of Fever-Like Whole-Body Hyperthermia on Lymphocyte Spectrin Distribution, Protein Kinase C Activity, and Uropod Formation." Journal of Immunology 162, no. 6 (1999): 3378–87. http://dx.doi.org/10.4049/jimmunol.162.6.3378.

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Abstract Regional inflammation and systemic fever are hallmarks of host immune responses to pathogenic stimuli. Although the thermal element of fever is thought to enhance the activity of immune effector cells, it is unclear what the precise role of increased body temperatures is on the activation state and effector functions of lymphocytes. We report here that mild, fever-like whole body hyperthermia (WBH) treatment of mice results in a distinct increase in the numbers of tissue lymphocytes with polarized spectrin cytoskeletons and uropods, as visualized in situ. WBH also induces a coincident
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Hochecker, Barbara, Katja Matt, Melanie Scherer, Alica Meßmer, Alexander von Ardenne, and Jörg Bergemann. "Heat vs. Fatigue: Hyperthermia as a Possible Treatment Option for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)." International Journal of Molecular Sciences 26, no. 11 (2025): 5339. https://doi.org/10.3390/ijms26115339.

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The aetiology and pathophysiology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) have not yet been clarified. Its exact diagnosis is also difficult because it has no biomarkers. This lack of knowledge leads to difficulties in treating the disease. In our work, we are attempting to counteract this problem by analysing the central cellular mechanisms in ME/CFS patients and comparing them with those of healthy individuals. This pilot study provides a small glimpse into the journey of nine people with ME/CFS—more specifically, how their peripheral blood mononuclear cells (PBMCs) re
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Cronau, L. H., D. L. Bourke, and J. M. Bull. "CARDIOVASCULAR EFFECTS OF WHOLE BODY HYPERTHERMIA (WBH) (≥ 41.5 °C) DURING GENERAL ANESTHESIA." Anesthesiology 63, Supplement (1985): A1. http://dx.doi.org/10.1097/00000542-198509001-00001.

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Xu, Zhongming, Qinghua Wang, Yansong He, Zhifei Zhang, Shu Li, and Mengran Li. "An Improved Algorithm for Noise Source Localization Based on Equivalent Source Method." Shock and Vibration 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/8302862.

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Near-field acoustical holography (NAH) based on the equivalent source method (ESM) is an efficient method applied for noise source identification. Asl2-norm-based regularization cannot produce a satisfactory solution of the ill-conditioned problem in high frequency, the conventional ESM is restricted to relatively low frequency, and the resolution of conventional ESM in middle to high frequency remains a limitation open to investigation. This article presents an algorithm known as improved functional equivalent source method (IFESM), designed to enhance the resolution of conventional ESM. This
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McCullough, Patrick E., Diego Gómez De Barreda, Thomas V. Reed, Jialin Yu, and F. Clint Waltz. "Sod Harvesting Intervals of Four Warm-Season Turfgrasses for Halosulfuron and Sulfentrazone." Weed Technology 28, no. 1 (2014): 47–57. http://dx.doi.org/10.1614/wt-d-13-00083.1.

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Sedges are problematic weeds that reduce quality of turfgrass sod, and herbicides may be needed for control prior to harvesting. The objective of this research was to evaluate application timing of halosulfuron and sulfentrazone on sod quality, tensile strength, and postharvest rooting of four warm-season turfgrasses. Bermudagrass injury from herbicides was minimal (< 10%), but injury to centipedegrass, St. Augustinegrass, and zoysiagrass was detected before harvesting and generally increased with sulfentrazone rate from 0.21 to 0.84 kg ai ha−1. Sod tensile strength was not reduced from the
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King, Yueh-Tsu, Chih-Sheng Lin, Jyh-Hung Lin, and Wen-Chuan Lee. "Whole-body hyperthermia-induced thermotolerance is associated with the induction of Heat Shock Protein 70 in mice." Journal of Experimental Biology 205, no. 2 (2002): 273–78. http://dx.doi.org/10.1242/jeb.205.2.273.

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SUMMARY Molecular mechanisms of whole-body thermotolerance (WBT) in mammals have not been investigated thoroughly. The purpose of this study was to assess the induction of the 70 kDa heat shock protein (HSP70) and antioxidant enzyme activity in animal WBT, which was induced by whole-body hyperthermia (WBH) in mice. As a preconditioning treatment, WBH was applied to mice to induce WBT. Synthesis of inducible HSP70 (HSP70i) and quantification of its increased level in liver were investigated by one- and two-dimensional polyacrylamide gel electrophoresis and immunoblotting. HSP70i synthesis in mi
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Cękalska, Marta. "Początki „Przeglądu Historyczno- -Wojskowego” (1929–1939)." Przegląd Historyczno-Wojskowy 20, no. 4 (2019): 11–43. http://dx.doi.org/10.32089/wbh.phw.2019.4(270).0001.

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The aim of the paper is to present the circumstances surrounding the establishment of the scientific journal „Military Historical Review” (PHW) in 1929. It was created on the initiative of the head of the Military Historical Bureau (WBH), Brigadier General Julian Stachiewicz, and focused on the military history until 1863. The supervision of the periodical was handed over to the head of the Independent Department of Previous Wars of the WBH, Major Otton Laskowski, and it featured publications of military, but above all civil researchers. The article presents the first concepts concerning the s
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Elmehdi, Hussein M. "An evaluation of web-based homework (WBH) delivery systems: University of Sharjah Experience." International Journal of Emerging Technologies in Learning (iJET) 8, no. 4 (2013): 57. http://dx.doi.org/10.3991/ijet.v8i4.2966.

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Alonso, K. "Cytokine levels in adult patients with solid tumours undergoing whole body hyperthermia (WBH)." International Journal of Hyperthermia 13, no. 5 (1997): 559–60. http://dx.doi.org/10.3109/02656739709023554.

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Gijsen, Matthias, Dirk Vlasselaers, Isabel Spriet, and Karel Allegaert. "Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine." Antibiotics 10, no. 10 (2021): 1182. http://dx.doi.org/10.3390/antibiotics10101182.

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Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors. Specific to the intensive care setting, such factors include critical illness, inflammatory status, augmented renal clearance (ARC), as well as therapeutic interventions (e.g., extracorporeal organ support systems or whole-body hypothermia [WBH]). This narrative review illustrates the relevance of both maturational and non-maturational changes in ab
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Niu, Xiaojing, Xiaomei Zhao, Dongfan Xie, and Jun Bi. "Modeling and Control of Network Macroscopic Fundamental Diagram during Holidays: A Case Study of Qingming Festival in Tianjin." Applied Sciences 13, no. 14 (2023): 8399. http://dx.doi.org/10.3390/app13148399.

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In this paper, the macroscopic traffic states and network traffic dynamics during the Qingming Festival holiday are explored with the Macroscopic Fundament Diagram (MFD), including the weekday before the holiday (WBH), the day of Qingming Festival (DQF), and the ordinary weekday (OW). The network is heterogeneous on the densities’ distribution, and the congested areas are different in location and size. Normalized Cut (Ncut) algorithm is used to partition the heterogeneous network into multiple homogeneous subregions. The MFD of each subregion is distributed within the critical density on the
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Ganta, Chanran K., Frank Blecha, Roman R. Ganta, et al. "Hyperthermia-enhanced splenic cytokine gene expression is mediated by the sympathetic nervous system." Physiological Genomics 19, no. 2 (2004): 175–83. http://dx.doi.org/10.1152/physiolgenomics.00109.2004.

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Whole body hyperthermia (WBH) has been used in experimental settings as an adjunct to radiochemotherapy for the treatment of various malignant diseases. The therapeutic effect of WBH has been hypothesized to involve activation of the immune system, although the effect of hyperthermia-induced activation of sympathetic nerve discharge (SND) on splenic immune function is not known. We tested the hypothesis that heating-induced splenic sympathoexcitation would alter splenic cytokine gene expression as determined using gene array and real-time RT-PCR analyses. Experiments were performed in splenic-
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