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Articles de revues sur le sujet "White House (D.C.) 2"
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Trezona, M., B. P. Mullan, D. N. D'Souza, F. R. Dunshea, D. W. Pethick, M. D'Antuono, M. McGrath et J. R. Pluske. « Influence of housing type and age in female pigs. 2. Effects on biochemical indicators of fat metabolism and the fatty acid profile of belly fat and back fat depots ». Animal Production Science 51, no 5 (2011) : 434. http://dx.doi.org/10.1071/an10181.
Texte intégralRésumé :
Weaning pigs into deep-litter (D) housing systems and then moving them into conventional (C) housing facilities affects the growth paths of the pigs and can result in differences in carcass composition which may be explained by altered fat metabolism. To examine this proposition experimentally, 160 female Large White × Landrace pigs were obtained at 3 weeks of age, average liveweight 5.5 ± 0.08 kg and were stratified by weight to four treatments. The treatments consisted of two housing treatments, C or D, across two growth periods: (i) early (3–13 weeks of age); and (ii) late (13–24 weeks of age). At ~13 weeks of age eight pigs per experimental treatment (n = 32) were slaughtered and the remaining pigs (n = 128) moved to new pens where they were housed until slaughter at ~24 weeks of age. To 13 weeks of age, the effect of housing type on lipogenesis did not reach significance (P > 0.05). At 24 weeks of age there were some treatment differences in fatty acid profile (P ≤ 0.05) and the concentration of plasma glycerol (P = 0.002) and non-esterified fatty acids (P = 0.019). There were trends for lipogenic enzyme activity to differ between treatments also (P < 0.100). Results suggested fat deposition was lower in D-finished pigs compared with C-finished pigs, rejecting the hypothesis that D-finished pigs would be fatter. However, most of the differences in the biochemical measurements were explained by the significant reduction in growth that occurred when pigs changed housing environments, rather than as an effect of the housing environment itself. Indicators of lipogenesis suggested that lipogenic rate was lowest in pigs moved from C to D housing compared with other treatment groups that had remained within the same housing, C or D, throughout the experiment or had moved from D housing to C housing at 13 weeks of age.
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Abeyrathne, Nalaka Sandun. « Use of lysozyme from chicken egg white as a nitrite replacer in an Italian-type chicken sausage ». Functional Foods in Health and Disease 5, no 9 (30 septembre 2015) : 320. http://dx.doi.org/10.31989/ffhd.v5i9.217.
Texte intégralRésumé :
Background: Sodium or potassium nitrite is widely used as a curing agent in sausages and other cured meat products. Nitrite has strong antimicrobial and antioxidant effects and generates cured meat color. Nitrite, however, can react with secondary or tertiary amines in meat to form carcinogenic, teratogenic and mutagenic N-nitroso compounds. Several findings have been suggested that high consumption of processed meat may increase the risk of cancer, and emphasized that dietary nitrosamines are positively associated with cancer. Lysozyme is one of the major egg proteins that have antimicrobial and antioxidant characteristics. Therefore, lysozyme can be used in meat processing to prevent microbial growth and oxidative degradation in meat products during storage. This study is focused on evaluating the antimicrobial and antioxidant effects of lysozyme extracted from egg white as a replacer of nitrite in a cooked Italian-type chicken sausage.Methods: Four curing treatments including 100% nitrite (control), 100% lysozyme (treatment 1), 25% nitrite + 75% lysozyme (treatment 2) and 50% nitrite + 50% lysozyme (treatment 3) were used to prepare Italian-type chicken sausage samples. Recipe was developed with 64% (w/w) meat, 17% (w/w) binder (bread crumble), 12% (w/w) ice, 4% (w/w) vegetable oil, 2% (w/w) salt, 1% (w/w) spices (chili, black pepper, cardamom). Prepared samples were cooked in an 80 °C smoke house to a core temperature of 65 °C and cooled in cold water to 20-25 °C subsequently packed in polyethylene and stored in a freezer (-18 °C). The antimicrobial effect lysozyme was tested using Escherichia coli and Salmonella. The growth of these pathogens at 0, 3 and 5 days of storage of spore inoculation was determined. The antioxidant activity of lysozyme was determined using the TBARS value during the 25 d storage period. The redness (a*), lightness (L*), and yellowness (b*) of sausages were analyzed using a Minolta color meter (CR 410, Konica Minolta Inc., Japan). The proximate composition (AOAC, 2002) of frozen (-18 °C) sausage samples and sensory properties of cooked samples were determined.Results: 50% nitrite + 50% lysozyme (treatment 3) was as effective as control (100% nitrite) in suppressing the growth of Escherichia coli, Salmonella and limiting lipid oxidation in the Italian-type chicken sausage. Treatment 3 was not significantly different from the control, for lightness (L*), redness (a*) and yellowness (b*) values (P > 0.05) but showed the best sensory characteristics among the treatments (p < 0.05). Moisture content of control sample was significantly higher (p < 0.05) than other treatments while crude protein, crude fat, crude fiber and ash content were not significantly differ each. In term of the cost, both treatment 3 and control have shown approximately equal values.Conclusion: This study demonstrated that lysozyme can be used as an effective nitrite replacer in the Italian-type chicken sausage. Replacing 50% of nitrate salt with 50% lysozyme did not show any negative effects in controlling microbial growth, preventing lipid oxidation, and color changes but improved the sensory characteristics.Keywords: Italian-type chicken sausage, nitrite, lysozyme, antimicrobial, antioxidant
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Nsekuye, Olivier, Edson Rwagasore, Marie Aime Muhimpundu, Ziad El-Khatib, Daniel Ntabanganyimana, Eric Noël Kamayirese, Laurent Ruyange et al. « Investigation of Four Clusters of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Rwanda, 2020 ». International Journal of Environmental Research and Public Health 18, no 13 (30 juin 2021) : 7018. http://dx.doi.org/10.3390/ijerph18137018.
Texte intégralRésumé :
We reported the findings of the first Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) four clusters identified in Rwanda. Case-investigations included contact elicitation, testing, and isolation/quarantine of confirmed cases. Socio-demographic and clinical data on cases and contacts were collected. A confirmed case was a person with laboratory confirmation of SARS-CoV-2 infection (PCR) while a contact was any person who had contact with a SARS-CoV-2 confirmed case within 72 h prior, to 14 days after symptom onset; or 14 days before collection of the laboratory-positive sample for asymptomatic cases. High risk contacts were those who had come into unprotected face-to-face contact or had been in a closed environment with a SARS-CoV-2 case for >15 min. Forty cases were reported from four clusters by 22 April 2020, accounting for 61% of locally transmitted cases within six weeks. Clusters A, B, C and D were associated with two nightclubs, one house party, and different families or households living in the same compound (multi-family dwelling). Thirty-six of the 1035 contacts tested were positive (secondary attack rate: 3.5%). Positivity rates were highest among the high-risk contacts compared to low-risk contacts (10% vs. 2.2%). Index cases in three of the clusters were imported through international travelling. Fifteen of the 40 cases (38%) were asymptomatic while 13/25 (52%) and 8/25 (32%) of symptomatic cases had a cough and fever respectively. Gatherings in closed spaces were the main early drivers of transmission. Systematic case-investigations contact tracing and testing likely contributed to the early containment of SARS-CoV-2 in Rwanda.
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Kim, Kwangwook, Yijie He, Cynthia Jinno, Seijoo Yang, Minho Song, Peng Ji et Yanhong Liu. « 142 Effects of antibiotics on blood profiles in weanling pigs experimentally infected with a pathogenic E. coli ». Journal of Animal Science 97, Supplement_2 (juillet 2019) : 78. http://dx.doi.org/10.1093/jas/skz122.143.
Texte intégralRésumé :
Abstract The experiment was conducted to investigate the effects of antibiotics on blood profiles and serum inflammatory mediators of weaned pigs experimentally infected with F18 Escherichia coli (E. coli). Twenty-six pigs (6.88 ± 1.03 kg BW) were individually housed in disease containment rooms and randomly allotted to one of three treatments with 8–12 replicate pigs per treatment. The three dietary treatments were control diet and 2 additional diets supplemented with 0.5 or 50 mg/kg carbadox, respectively. The experiment lasted 18 d (7 d before and 11 d after first inoculation [d 0]). F18 E. coli inoculum was daily and orally as 1010 cfu/3 mL for 3 d. Blood samples were collected before E. coli inoculation and on d 2, 5, 8, and 11 post-inoculation (PI). Total and differential blood cell count were analyzed by CBC test. All data were analyzed by ANOVA using PROC MIXED of SAS. Supplementation of low-dose antibiotics had greatest (P < 0.05) neutrophils but lowest (P < 0.05) monocytes on d 2 PI, compared with control and high-dose antibiotics groups. Pigs in the low-dose antibiotics group still had higher (P < 0.05) white blood cell counts and lymphocytes than pigs in the other groups on d 11 PI. In consistent with CBC results, pigs supplemented with low-dose antibiotics had greatest (P < 0.05) serum C-reactive protein on d 2 and 5 PI and serum TNF-α on d 5 PI, compared with pigs in the control and high-dose antibiotics groups. No differences were observed in the red blood cell profiles between pigs in control and low-dose antibiotics groups, whereas supplementation of high-dose antibiotics had lowest (P < 0.05) packed cell volume but highest (P < 0.05) mean corpuscular hemoglobin concentration among three treatments. In conclusion, low-dose antibiotic supplementation may exacerbate systemic inflammation caused by F18 E. coli infection.
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Wilbers, Kimberly, Bruce C. Shanks, James D. Caldwell, Megan Koppen et Kevin Adams. « PSI-12 Performance and carcass measurements by rabbits offered diets with and without a phytogenic feed additive ». Journal of Animal Science 98, Supplement_3 (2 novembre 2020) : 229. http://dx.doi.org/10.1093/jas/skaa054.400.
Texte intégralRésumé :
Abstract Weaning stress and other environmental conditions can impact growing rabbit performance and carcass measurements. Therefore, investigating a feed ingredient that may mitigate these effects is important. The objective of this study was to determine if the addition of a phytogenic feed additive would improve performance and carcass measurements of growing rabbits. On October 22nd, 2018, a total of 16 (1.01 ± 0.02 kg BW) New Zealand White male rabbits were weaned and stratified by BW and allocated randomly to 1 of 2 groups representing 2 treatments: 1) Control (C; no phytogenic; n = 8) and 2) 454 g/ton phytogenic feed additive (PHYTO; n = 8). During the 42-d study, rabbits were housed in individual cages and offered a 18% CP and 2% fat commercial grower diet. All rabbits had ad libitum access to feed and water. Rabbits were weighed at the start of the study and weekly thereafter until the end of the feeding period when they were transported to a local abattoir, harvested, and carcass measurements recorded. Data were analyzed using PROC MIXED of SAS. Start weight, weekly BW, end BW, weekly gain, total gain, weekly intake, total intake, and G:F did not differ (P ≥ 0.11) between treatments. Carcass shrink percentage was greater (P = 0.003) from PHYTO compared with C. Whereas, HCW and dressing percentage were greater (P < 0.05) from C compared with PHYTO. Loin width did not differ (P = 0.89) between treatments. Ultimate pH was lower (P = 0.02) from PHYTO compared with C. Therefore, offering this specific phytogenic to weaned rabbits may not improve performance, but may impact certain carcass measurements. Further research is warranted to explore phytogenic impacts on carcass acceptability.
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Palmateer, A. J., P. Lopez, T. E. Seijo et N. A. R. Peres. « Severe Outbreak of Downy Mildew Caused by Plasmopara obducens on Impatiens walleriana in Florida ». Plant Disease 97, no 5 (mai 2013) : 687. http://dx.doi.org/10.1094/pdis-08-12-0705-pdn.
Texte intégralRésumé :
Impatiens, Impatiens walleriana Hook.f., are grown as an ornamental crop in greenhouse and shade house production in Florida and other regions of the United States. Downy mildew on impatiens was detected from numerous landscapes (Manatee, Hillsborough, Collier, Hendry, Broward, Palm Beach, and Miami-Dade counties) in the winter of 2012. Incidence reached nearly 100% on many affected landscape plantings. Symptoms initially appeared as yellowing on the lower leaves and were typically vein-delineated, although in some cases the entire leaf was affected. Diseased plants later wilted and infected leaves abscised from the stem. A white, downy growth was apparent on the abaxial leaf surface. Microscopic observation revealed coenocytic mycelium with sporangiophores that were hyaline, thin-walled, and had slightly swollen bases. Branches of sporangiophores were monopodial and formed right angles to the supporting branches. Sporangia were hyaline and obvoid with a single pore on the distal ends that was mostly flat. Sporangia measured 19 to 22.5 × 13 to 17 μm. Oospores were observed in stem and leaf tissue. Leaves of 10 potted impatiens plants, I. walleriana ‘Super Elfin XP Coral’ and ‘Super Elfin XP White,’ were inoculated with a suspension containing 1 × 105 sporangia/ml and sprayed till runoff (approximately 20 ml per plant) with a handheld pressurized Ulva sprayer. Plants were maintained outside in a shade house under 73% shade where the daytime temperatures averaged 24°C and RH averaged 74% and nighttime temperature averaged 18°C with an average of 91% RH. Ten non-inoculated impatiens plants served as controls. After 10 days, symptoms typical of downy mildew occurred on 100% of the inoculated impatiens plants and sporulation was confirmed microscopically. The non-inoculated control plants remained healthy. The 5′ end of the large ribosomal subunit gene (762 bp) from two isolates, one collected in Hillsborough County and one from Miami-Dade County, was amplified by PCR (primers NL1-GCATATCAATAAGCGGAGGAAAAG and NL4-GGTCCGTGTTTCAAGACGG) and sequenced bi-directionally (1,2,3). The consensus sequence from both isolates was identical and it was deposited into GenBank (Accession No. JX217746). Sequence data matched (99% homology) with Plasmopara obducens reported on I. walleriana in Europe and Australia (1,2). To our knowledge, this is the first report of downy mildew on I. walleriana in Florida (4). The disease has made a major impact on impatiens in landscapes throughout Florida and will likely continue to affect future production. References: (1) A. Bulajic et. al. Plant Dis. 95:491, 2011. (2) J. H. Cunnington et. al. Plant Pathol. 57:371, 2008. (3) K. O'Donnell. Curr. Genet. 22:213, 1992. (4) D. F. Farr et al. Fungi on Plants and Plant Products in the United States. The American Phytopathological Society, 1989.
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Laskin, A. A., A. A. Babakhin, O. Y. Kamishnikov, I. S. Gushchin et M. R. Khaitov. « Allergen-specific immunotherapy with monomeric allergoid from house dust mites dermato-phagoides pteronyssinus in a mouse allergic rhinitis model ». Russian Journal of Allergy 13, no 6 (15 décembre 2016) : 43–51. http://dx.doi.org/10.36691/rja367.
Texte intégralRésumé :
Background. The aim of this study was to investigate the efficacy of the allergen-specific immunotherapy (ASIT) with monomeric allergoid (sD1) obtained by succinylation of the allergenic extract from house dust mite Dermatophagoides pteronyssinus (D. pteronyssinus) (D1) in experimental mouse allergic rhinitis model (MARM). Materials and methods. BALB/c mice were immunized with non-modified extract D1 from house dust mite D. pteronyssinus (Der p) in mixture with aluminum hydroxide [Al(OH)3] three times in a three week intervals and then in 6 weeks after the last immunization were challenged with allergenic extract D1 by intranasal administration. Experimental ASIT was performed during the interval between the last immunization and the beginning of challenge. The first group of animals was treated with «sham ASIT» receiving of 16 subcutaneous (s.c.) injections of phosphate-buffered saline (PBS); the second group received 16 s.c. injections of non-modified D1 in increasing doses (in protein equivalent): 1; 10; 100 and 1000 pg/mouse; the third group received 8 s.c. injections ofsDl in increasing doses (in protein equivalent): 100; 550 and 1000 pg/mouse; the fourth group received combined ASIT consisted of 4 s.c. injections of sD1 in doses (in protein equivalent): 100; 550; 1000 pg/mouse and 4 sublingual (s.l.) administrations of sD1 in a dose of 1000 pg/mouse. The fifth group served as a negative control and received sham immunization, ASIT and challenge with PBS. Immediately after the last challenge and 24 hours later the clinical signs of MARM: sneezings (counts per minute) and breath frequency (assessed by non-invasive plethysmography) were evaluated. 48 hours after the last challenge animals of all groups were sacrificed and necessary material (whole head) was collected for histological assessment of the severity of allergic rhinitis in the nasal cavity. To obtain sera samples blood was collected from all groups of animals three times: 7 days after final immunization, 1 day before the challenge and 24 hours after the last challenge. Levels of anti-Der p IgE, IgG1, IgG2a in individual sera samples were determined by enzyme-linked immunosorbent assay (ELISA). Results. It is shown that all three variants of ASIT (groups 2, 3, 4) significantly reduced the number of sneezing acts. The greatest decrease was seen in the group 3 which was treated s.c with monomeric allergoid sD1. The number of respiratory acts per minute in the animals of groups 2 and 4 treated with non-modified D1 and monomeric allergoid sD1 (combined ASIT - s.c. and s.l. administration) respectively, were significantly higher than that of group 1 (MARM). The levels of anti-Der p IgE in groups 1, 2, 3 and 4 were increased after the 3rd immunization in comparison with group 5 (negative control). After ASIT the levels of anti-Der p IgE in groups 2, 3 and 4 were elevated in compare to group 5 (negative control) and group 1 (positive control - MARM). However, after the challenge the highest levels of anti-Der p IgE were observed in groups 1 and 4, while in group 3 we saw a moderate decrease of anti-Der p IgE and in the group 2 the levels of anti-Der p IgE were significantly lower than that of group 1 (MARM). The levels of anti-Der p IgG1 were significantly increased in groups 2, 3, 4 during and after ASIT as well as after challenge. The levels of anti-Der p IgG2a in groups 3 and 4 demonstrated a trend of increasing after ASIT. Anti-Der p IgG2a levels in group 4 after the challenge were significantly higher than that of group 1 (MARM). Histological evaluation has shown that overall inflammation, mucous exudation, hyperplasia of the mucosa in the nasal cavity were expressed significantly in groups 1 and 2 in comparison with group 5 (negative control). At the same time group 2 demonstrated a slight reduction of features designated above, and in groups 3 and 4 (ASIT with sD1 and combined s.c/s.l. ASIT, respectively) we observed a complete suppression of these inflammation parameters. Conclusion. These data indicate that ASIT with monomeric allergoid from house dust mite D. pteronyssinus obtained by succinylation may be a novel safe and effective approach for the treatment of allergic rhinitis including carrying out of combined course of injectable and sublingual therapy that may enhance the effect of treatment and patients’ quality of life.
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Espinosa, Charmaine D., Robert Scott Fry, Matthew Kocher et Hans H. Stein. « 125 Effects of copper hydroxychloride and increasing concentrations of dietary fat on growth performance, total tract endogenous loss of fat, and apparent total tract digestibility of fat by growing pigs ». Journal of Animal Science 97, Supplement_2 (juillet 2019) : 68. http://dx.doi.org/10.1093/jas/skz122.125.
Texte intégralRésumé :
Abstract Two experiments were conducted to test the hypothesis that Cu hydroxychloride (IntelliBond C, Micronutrients, LLC, Indianapolis, IN) improves gain:feed of pigs by increasing apparent total tract digestibility (ATTD) of fat. In experiment 1, 144 pigs (15.40 ± 2.39 kg) were allotted to 1 of 6 treatments. Four diets contained 0, 2, 4, or 6% choice white grease (CWG) and 2 diets contained 150 mg/kg Cu from Cu hydroxychloride and 0 or 2% CWG. Data for growth performance were analyzed by contrast statements, and Cu equivalency of CWG was determined using prediction equations derived from regression procedures using SAS. Results indicated that gain:feed linearly increased (P ≤ 0.05) as CWG concentration increased in diets (Table 1). Supplementation of Cu hydroxychloride to diets improved (P ≤ 0.05) gain:feed of pigs, which resulted in a CWG equivalence of 2.8 to 3.8% for 150 mg/kg Cu hydroxychloride. In experiment 2, 80 pigs (18.24 ± 1.81 kg) were housed individually in metabolism crates and randomly allotted to 1 of 10 diets. Eight diets contained 0, 15, 30, or 45% distillers dried grains with solubles (DDGS) and 0 or 150 mg/kg Cu hydroxychloride. Two additional diets contained 2% CWG and 15% DDGS and 0 or 150 mg/kg Cu hydroxychloride. Feces were collected for 4 d after 5 d adaptation. Data were analyzed by contrast statements and regression procedures using SAS. Supplementation of Cu to diets improved (P ≤ 0.05) ATTD of fat by 20% due to reduced (P ≤ 0.05) endogenous loss of fat (from 11.23 to 7.14 g/kg dry matter intake), but did not affect energy digestibility or true total tract digestibility of fat. In conclusion, supplementation of 150 mg/kg Cu hydroxychloride to diets improved gain:feed of pigs with a CWG equivalence of 2.8 to 3.8%, but this was not due to improved energy digestibility.
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Sharov, Konstantin S. « The Problem of Transcribing and Hermeneutic Interpreting Isaac Newton’s Archival Manuscripts ». Tekst. Kniga. Knigoizdanie, no 24 (2020) : 134–55. http://dx.doi.org/10.17223/23062061/24/7.
Texte intégralRésumé :
In the article, the current situation and future prospects of transcribing, editing, interpreting, and preparing Isaac Newton’s manuscripts for publication are studied. The author investigates manuscripts from the following Newton’s archives: (1) Portsmouth’s archive (Cambridge University Library, Cambridge, UK); (2) Yahuda collection (National Library of Israel, Jerusalem, Israel); (3) Keynes collection (King’s College Library, Cambridge University, Cambridge, UK); (4) Trinity College archive (Trinity College Library, Cambridge University, Cambridge, UK); (5) Oxford archive (New’s College Library, Oxford University, Oxford, UK); (6) Mint, economic and financial papers (National Archives in Kew Gardens, Richmond, Surrey, UK); (7) Bodmer’s collection (Martin Bodmer Society Library, Cologny, Switzerland); (8) Sotheby’s Auction House archive (London, UK); (9) James White collection (James White Library, Andrews University, Berrien Springs, Michigan, US); (10) St Andrews collection (University of St Andrews Library, St Andrews, UK); (11) Bodleian collection (Bodleian Library, Oxford University, Oxford, UK); (12) Grace K. Babson collection (Huntington Library, San Marino, California, US); (13) Stanford collection (Stanford University Library, Palo Alto, California, US); (14) Massachusetts collection (Massachusetts Technological Institute Library, Boston, Massachusetts, US); (15) Texas archive (Harry Ransom Humanities Research Centre, University of Texas Library, Austin, Texas, US); (16) Morgan archive (Pierpont Morgan Library, New York, US); (17) Fitzwilliam collection (Fitzwilliam Museum, Cambridge University, Cambridge, UK); (18) Royal Society collection (Royal Society Library, London, UK): (19) Dibner collection (Dibner Library, Smithsonian Institution, Washington D.C., US); (20) Philadelphia archive (Library of the American Philosophical Society, Philadelphia, Pennsylvania, US). There is a great discrepancy between what Newton wrote (approx. 350 volumes) and what was published thus far (five works). It is accounted for by a number of reasons: (a) ongoing inheritance litigations involving Newton’s archives; (b) dispersing Newton’s manuscripts in countries with different legal systems, consequently, dissimilar copyright and ownership branches of civil law; (c) disappearance of nearly 15 per cent of Newton works; (d) lack of accordance of views among Newton’s researchers; (e) problems with arranging Newton’s ideas in his possible Collected Works to be published; (f) Newton’s incompliance with the official Anglican doctrine; (g) Newton’s unwillingness to disclose his compositions to the broad public. The problems of transcribing, editing, interpreting, and pre-print preparing Newton’s works, are as follows: (a) Newton’s complicated handwriting, negligence in spelling, frequent misspellings and errors; (b) constant deletion, crossing out, and palimpsest; (c) careless insertion of figures, tables in formulas in the text, with many of them being intersected; (d) the presence of glosses situated at different angles to the main text and even over it; (e) encrypting his meanings, Newton’s strict adherence to prisca sapientia tradition. Despite the obstacles described, transcribing Newton’s manuscripts allows us to understand Sir Newton’s thought better in the unity of his mathematical, philosophical, physical, historical, theological and social ideas.
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Zhang, G. Z., et C. Y. Tang. « First Report of Acrostalagmus luteo-albus Causing Red Rust of Needle Mushroom (Flammulina velutipes) in China ». Plant Disease 99, no 1 (janvier 2015) : 158. http://dx.doi.org/10.1094/pdis-07-14-0728-pdn.
Texte intégralRésumé :
Needle mushroom (Flammulina velutipes) is an edible and medicinal mushroom with annual production yields for China exceeding 2 million metric tons. Hebei province is one of the biggest producers of needle mushrooms in China. From 2009 to 2010, red rust-colored sporulation (fungal mycelia and conidia) was found on the substrate surface of white needle mushroom bags in more than 10 mushroom cultivation operations in Hebei. The rust-colored sporulation covered the substrate surface, where the development of the fruiting bodies was inhibited; the stipes were sparse and became light brown when the substrate was slightly affected. The fruiting bodies on severely affected substrate were unable to complete development or shriveled and died off on the substrate. More than 30 to 40% substrate bags were contaminated with the red rust mold, with approximately a 40% yield reduction in each production house. Single conidia were isolated from the red rust mold and cultured on potato dextrose agar at 25°C in the dark. The colony was round, compact, reddish-brown, and slow-growing (2 to 3 mm/d). Main conidiophore axes were erect, often branched in five to seven layers, tapered from the base to the upper part, pale reddish brown at the base, and almost hyaline at the apex. Two to five phialides usually verticillated at each level along the main stipe and its branches. Phialides were narrowly flask-shaped and only very slightly swollen at the base. Conidia were oval, measured 3.5 to 5.4 (4.5) × 2.3 to 3.6 (3.0) μm, L/W = 1.2 to 2.0 (1.5), and formed pale reddish brown, slimy heads. The isolate was tentatively identified as Acrostalagmus luteo-albus based on its morphological characteristics (2). For molecular analysis, the internal transcribed spacer (ITS) regions of ribosomal DNA from the isolate were PCR-amplified using universal primers ITS1 and ITS4. The resulting sequence (Accession No. KC127681) submitted to GenBank had a 99% identity to that of A. luteo-albus (JN545827) isolated from vineyard soil and Accession No. JQ387575 isolated from twig of declining persimmon tree. To confirm the pathogenicity of the isolate to needle mushroom, five bags of needle mushroom with stipes of 1 to 2 cm long were inoculated with a conidia suspension (105 conidia/ml) of the isolate and incubated at 13 to 15°C in the dark, while five non-inoculated bags (sprayed with sterile water only) were used as a control. Five days after inoculation, the development of the fruiting body was obviously inhibited, and a few growing fruiting bodies became light brown, compared with the non-inoculated fruiting bodies, which were growing healthily and fast and were white with no symptoms. The pathogen was re-isolated from the inoculated fruiting bodies. A. luteo-albus is primarily saprophytic but is sometimes pathogenic. Indeed, it has been associated with post-harvest rot of ginger rhizomes in Brazil (1). To our knowledge, this is the first report of A. luteo-albus causing damage to needle mushroom in China. References: (1) S. I. Moreira et al. Trop. Plant Pathol. 38:218, 2013. (2) R. Zare et al. Mycol. Res. 108:576, 2004.
Chapitres de livres sur le sujet "White House (D.C.) 2"
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Taber, Douglass F. « Metal-Mediated C–C Ring Construction : The Ding Synthesis of (−)-Indoxamycin B ». Dans Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0075.
Texte intégralRésumé :
Shou-Fei Zhu of Nankai University developed (Angew. Chem. Int. Ed. 2014, 53, 13188) an iron catalyst that effected the enantioselective cyclization of 1 to 2. Bypassing diazo precursors, Junliang Zhang of East China Normal University used (Angew. Chem. Int. Ed. 2014, 53, 13751) a gold catalyst to cyclize 3 to 4. Taking advantage of energy transfer from a catalytic Ir complex, Chuo Chen of University of Texas Southwestern carried out (Science 2014, 346, 219) intramolecular 2+2 cycloaddition of 5, leading, after dithiane formation, to the cyclobutane 6. Intramolecular ketene cycloaddition has been limited in scope. Liming Zhang of the University of California Santa Barbara found (Angew. Chem. Int. Ed. 2014, 53, 9572) that intramolecular oxidation of an intermediate Ru vinylidene led to a species that cyclized to the cyclobutanone 8. James D. White of Oregon State University devised (J. Am. Chem. Soc. 2014, 136, 13578) an iron catalyst that mediated the enantioselective Conia-ene cyclization of 9 to 10. Xiaoming Feng of Sichuan University observed (Angew. Chem. Int. Ed. 2014, 53, 11579) that the Ni-catalyzed Claisen rearrangement of 11 proceeded with high diastereo- and enantiocontrol. The relative configuration of the product 12 was not reported. Robert H. Grubbs of Caltech showed (J. Am. Chem. Soc. 2014, 136, 13029) that ring opening cross metathesis of 13 with 14 delivered the Z product 15. Mn(III) cyclization has in the past required a stoichiometric amount of inorganic oxidant. Sangho Koo of Myong Ji University found (Adv. Synth. Catal. 2014, 356, 3059) that by adding a Co co- catalyst, air could serve as the stoichiometric oxidant. Indeed, 16 could be cyclized to 17 using inexpensive Mn(II). Matthias Beller of the Leibniz-Institüt für Katalyse prepared (Angew. Chem. Int. Ed. 2014, 53, 13049) the cyclohexene 20 by coupling the racemic alcohol 18 with the amine 19. Paultheo von Zezschwitz of Philipps-Universität Marburg added (Chem. Commun. 2014, 50, 15897) diethyl zinc in a conjugate sense to 21, then reduced the product to give 22. Depending on the reduction method, either diastereomer of the product could be made dominant. Nuno Maulide of the University of Vienna displaced (Angew. Chem. Int. Ed. 2014, 53, 7068) the racemic chloride 23 with diethyl zinc to give 24 as a single diastereomer.
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Taber, Douglass. « C-O Ring Containing Natural Products : Paeonilactone B (Taylor), Deoxymonate B (de la Pradilla), Sanguiin H-5 (Spring), Solandelactone A (White), Spirastrellolide A (Paterson) ». Dans Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0050.
Texte intégralRésumé :
Richard J. K. Taylor of the University of York has developed (Angew. Chem. Int. Ed. 2008, 47, 1935) the diasteroselective intramolecular Michael cyclization of phosphonates such as 2. Quenching of the cyclized product with paraformaldehyde delivered ( + )-Paeonilactone B 3. Roberto Fernández de la Pradilla of the CSIC, Madrid established (Tetrahedron Lett. 2008, 49, 4167) the diastereoselective intramolecular hetero Michael addition of alcohols to enantiomerically-pure acyclic sulfoxides such as 4 to give the allylic sulfoxide 5. Mislow-Evans rearrangement converted 5 into 6, the enantiomerically-pure core of Ethyl Deoxymonate B 7. The ellagitannins, represented by 10, are single atropisomers around the biphenyl linkage. David R. Spring of the University of Cambridge found (Organic Lett. 2008, 10, 2593) that the chiral constraint of the carbohydrate backbone of 9 directed the absolute sense of the oxidative coupling of the mixed cuprate derived from 9, leading to Sanguiin H-5 10 with high diastereomeric control. A key challenge in the synthesis of the solandelactones, exemplified by 14, is the stereocontrolled construction of the unsaturated eight-membered ring lactone. James D. White of Oregon State University found (J. Org. Chem. 2008, 73, 4139) an elegant solution to this problem, by exposure of the cyclic carbonate 11 to the Petasis reagent, to give 12. Subsequent Claisen rearrangement delivered the eight-membered ring lactone, at the same time installing the ring alkene of Solandelactone E 14. AD-mix usually proceeds with only modest enantiocontrol with terminal alkenes. None the less, Ian Paterson, also of the University of Cambridge, observed (Angew. Chem. Int. Ed. 2008, 47, 3016, Angew. Chem. Int. Ed. 2008, 47, 3021) that bis-dihydroxylation of the diene 17 proceeded to give, after acid-mediated cyclization, the bis-spiro ketal core 18 of Spirastrellolide A Methyl Ester 19 with high diastereocontrol.
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Ray, Keith, et Julian Thomas. « Introduction : Neolithic Britain—encounters and reflections ». Dans Neolithic Britain. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198823896.003.0008.
Texte intégralRésumé :
Is it possible to experience the Neolithic period (c.4000—c.2400 BCE) in Britain today? Of course not, or not in any literal sense. And yet, there are devices that we can create, and places that we can visit, that can to some extent stand in for that experience. These enable us, however fleetingly, to bridge the gulf of time that separates us from the distant world of thousands of years ago. One new way of traversing this chasm became available to us in 2013, when English Heritage opened a new visitor centre at Stonehenge. Inside the airy modern structure the latest audio-visual technology introduces visitors to the site and its surrounding prehistoric landscape. Remarkably, before the year was out, that centre had hosted a visit by the then President of the United States of America. Barack Obama made an unscheduled stop at the World Heritage Site en route from a NATO summit in Wales on 5 September 2014. Apparently, visiting Stonehenge, widely regarded as the most extraordinary of all prehistoric sites in Europe, was on the personal ‘bucket list’ of that recent incumbent of the White House. Among the things that the US President would have seen at the Stonehenge centre were reconstructed Late Neolithic houses from the area, and the visitor can now enter and walk around in these buildings, made using authentic materials. These newly constructed timber and daub buildings had been created on the basis of evidence recovered from Durrington Walls, a colossal Late Neolithic complex 2 miles from Stonehenge, where settings of concentric rings of massive posts were contained within an embanked enclosure half a kilometre across. Surprisingly, if the visitor centre had been built when it had originally been planned a decade earlier, it would not have been possible to recreate these 4,500-year-old houses, with their square ground plans and central hearths. This is because the excavations that would reveal these striking vestiges of the Stonehenge people were then only just beginning. This is an indication of the pace of discovery in the study of Neolithic Britain, and the immediacy of this process is one of the things that we would like to convey in this book.
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Crouch, Dora P. « Profile of Individual Water User ». Dans Water Management in Ancient Greek Cities. Oxford University Press, 1993. http://dx.doi.org/10.1093/oso/9780195072808.003.0036.
Texte intégralRésumé :
One way to show our understanding of ancient Greek management of water is to follow an ordinary person in her daily patterns, observing when and how she uses water. This schedule ignores differences that derive from local geology, climate, or customs, but rather tries to set out the common patterns. 1. At daylight. Wake up. Go to room or alcove set aside for excreting and do that. Rinse with previously used water. Then go to courtyard, pull up bucket of water from cistern, pour into louter, and wash face and hands. Save water for re-use (Fig. 13.3). 2. First meal. Fix breakfast, using water from cistern for any cooking. Water donkey, dog, house plants, with water from cistern or re-usable water from cooking or bathing. 3. Work. Morning and mid-afternoon to late day: A. Do family laundry—use giant pithos or scrub-board at edge of courtyard, filled from downspout from roof or with buckets of water from the cistern; hang clothes to dry on poles or rope strung between posts (columns) supporting roofs around courtyard. Alternate: laundry might be done communally at a large tank that received the overflow from a fountain near the agora, and the wet clothes carried home and spread out to dry, as above (Fig. 17.5). B. Or do craft activity such as making pottery, using courtyard and water from cistern. C. Or go out to farm. Excrement and garbage were probably carried daily to the farm for fertilizer. An important farming task was to monitor the irrigation of timber lots, fields, orchards, and vineyards with waste water from the town or with spring or river water or dispersed rainwater. D. Or do shopping and/or selling. Periodically carry craft items to Agora to sell them. If need be, rinse items such as vases in public fountains to show off their best colors. In Athens, women participated in the markets, selling lettuce and other farm or craft products, but in some Greek cities shopping and selling were solely masculine activities. 4. Recreation. A. Talk with cousin from the country who waters his donkey at the public trough in the Agora. B. On the way home stop at neighborhood fountain to chat with other people fetching water to drink (Fig. 21.1). C. On special occasions (marriage, birth) go to a sanctuary for a ritual bath. (Fig. 6.1).
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« Questions Q 57-1 How does the CISG determine the place where payment of the purchase price is to be made ? Q 57-2 a) To what extent is Art. 57 CISG a subsidiary rule ? Cf. also the corre-sponding provisions from the other legal systems. b) According to the INCOTERM ‘EXW’ (Ex Works (. . . named place)), the seller delivers when it places the goods at the disposal of the buyer at the seller’s premises or another named place (i.e. works, factory, ware-house, etc.). What does that mean in relation to where the buyer has to pay the purchase price ? Q 57-3 a) How must we distinguish Art. 57(1)(a) from Art. 57(1)(b) CISG ? b) Why is Art. 57(1)(b) CISG of higher practical importance than Art. 57(1)(a) ? Q 57-4 What kind of documents are addressed in Art. 57(1)(b) CISG ? (Cf. also C 58–1). Q 57-5 a) Does the CISG address the issue of where monetary obligations other than the purchase price are to be paid ? b) Which possible solutions are there to this question ? c) Compare Art. 57(1) CISG with the corresponding provisions of the UP 2004, PECL, OR, and ABGB. To what extent are they broader than Art. 57(1) CISG ? d) The way that the provisions mentioned in c) deal with the place of performance of monetary obligations is plain and simple. How can we make sure that the question is solved in the same way under the CISG ? Q 57-6 Compare Art. 57(1) CISG with the other legal provisions. a) Is it commonly acknowledged that the purchase price is paid at the seller’s place of business ? b) In particular, are there differences between Art. 57(1) CISG, on the one hand, and the UCC and the French CC, on the other • with regard to the structure of the corresponding provisions ? • in substance ? Q 57-7 If the seller’s place of business changes after the conclusion of the contract, where is payment to be made ». Dans International Sales Law, 472. Routledge-Cavendish, 2007. http://dx.doi.org/10.4324/9780203945445-153.
Texte intégral
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« they are called the appellants, and again lost. They then appealed to the House of Lords, where they also lost. There was a lot of money at stake : the difference between the £201.60 that the seeds cost as awarded by the Court of Appeal or the £90,000+ that the trial judge awarded. Consider, for a moment, what you have read and what you know so far. Does it seem fair to you that George Mitchell won ? If so, why ? If not, why not ? So far we have considered : (a) Procedural history. (b) Facts. (c) The operative rules of law : • It is known that both common law rules and statutory rules are relevant to the case. • Further, it is known that if the common law rules are found to apply in the seller’s favour he still has to jump the hurdle presented by the statutory rules. • Recall, if there is a clash between common law rules and statutory rules, the statutory rules prevail. (d) A verbatim account of the two issues in the case (however, these are probably not fully comprehended yet, despite Figures 4.13 and 4.14, above!) : • It is clear that Lord Bridge will argue through each of the issues. • If the appellants succeed in issue 1 they may still fail overall if they fail over issue 2. (Can you understand why ? The answer is in the first sentence of text setting out ‘the second issue’. See Figure 4.14, above.) • Logically, one would expect Lord Bridge to commence with the arguments over issue 1, the common law issue, as this is the gateway to an argument over issue 2 which will only take place if issue 1 is decided in the appellant’s favour (and this is contentious limitation clause what he does). (e) Understanding the clause. This is set out in Figure 4.15, below. Until all of these matters are linked and understood it is not possible to fully comprehend the reasoning in the case. Now take time to consolidate the information we have so far and return to the judgment of Lord Bridge, concentrating on his arguments concerning issue 1 (Appendix 1, p 310, para 3). 4.5.2.5 Stage 4 : breaking into Lord Bridge’s speech You will have already read Lord Bridge’s speech by now. It is also now appreciated that the arguments in this case are quite complex and the initial method of breaking into the text for understanding is to look at each paragraph. Paragraphs are intended to convey a new idea. So each paragraph represents an idea or a cluster of ideas. Careful ordering of paragraphs is essential in a piece of writing if a sense of progression is to be maintained. Therefore when reading for understanding a précis of each paragraph begins the process of understanding. » Dans Legal Method and Reasoning, 100. Routledge-Cavendish, 2012. http://dx.doi.org/10.4324/9781843145103-76.
Texte intégralActes de conférences sur le sujet "White House (D.C.) 2"
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Tokumaru, Kumon. « The Three Stage Digital Evolution of Linguistic Humans ». Dans GLOCAL Conference on Asian Linguistic Anthropology 2019. The GLOCAL Unit, SOAS University of London, 2019. http://dx.doi.org/10.47298/cala2019.12-2.
Texte intégralRésumé :
Digital Linguistics (DL) is an interdisciplinary study that identifies human language as a digital evolution of mammal analog vocal sign communications, founded on the vertebrate spinal sign reflex mechanism [Tokumaru 2017 a/b, 2018 a/b/c/d]. Analog signs are unique with their physical sound waveforms but limited in number, whilst human digital word signs are infinite by permutation of their logical property, phonemes. The first digital evolution took place 66,000 years ago with South African Neolithic industries, Howiesons Poort, when linguistic humans acquired a hypertrophied mandibular bone to house a descended larynx for vowel accented syllables containing logical properties of phonemes and morae. Morae made each syllable distinctive in the time axis and enabled grammatical modulation by alternately transmitting conceptual and grammatical syllables. The sign reflex mechanism is an unconscious self-protection and life-support mechanism, operated by immune cell networks inside the ventricle system. DL identified cellular and molecular structures for the sign (=concept) device as a B lymphocyte (or, in other words, Mobile Ad-Hoc Networking Neuron), connects to sensory, conceptual and networking memories, which consist of its meanings [Table 1]. Its antibodies can network with antigens of CSF-Contacting Neurons at the brainstem reticular formation and of Microglia cells at the neocortex [Figure 1]. It is plausible that the 3D structure of the antigen molecule takes the shape of word sound waveform multiplexing intensity and pitch, and that specifically pairing the antibody molecule consists of three CDRs (Complementality Defining Regions) in the Antibody Variable Region network with the logic of dichotomy and dualism. As sign reflex deals with survival issues such as food, safety and reproduction, it is stubborn, passive and inflexible: It does not spontaneously look for something new, and it is not designed to revise itself. These characteristics are not desirable for the development of human intelligence, and thus are to be overcome. All the word, sensory and network memories in the brain must be acquired postnatally through individual learning and thought. The reason and intelligence of humans depend on how correctly and efficiently humans learn new words and acquire appropriate meanings for them.
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Burshtin, Michael L. « The Pennsylvania Railroad GG1 Electric Locomotive : A Retrospective ». Dans 2020 Joint Rail Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/jrc2020-8002.
Texte intégralRésumé :
Abstract This paper is a historical review of the design and operation of the Pennsylvania Railroad’s class GG1 electric locomotive over its heavily-trafficked New York City-Washington, DC main line during the period 1934–1983. The locomotive was designed in-house by the railroad in corroboration with Baldwin Locomotive, General Electric and Westinghouse Electric following competitive tests of several electric locomotive designs. Its outstanding performance and long operating life has resulted in it being generally considered the most highly regarded electric locomotive in North America. The Pennsylvania Railroad embarked in the late 1920’s on a major AC electrification program for its New York-Washington and Philadelphia-Harrisburg main lines and local branches. It initially planned to use a fleet of class P5 rigid frame 2-C-2 electric locomotives for service. However problems were quickly encountered with damaging lateral track impacts, axle cracks, truck hunting, and inadequate tractive effort. The railroad responded with a series of competitive evaluation tests of several locomotive designs including a recent New York, New Haven & Hartford (NYNH&H) Railroad articulated frame locomotive, using an ingenious method to measure truck lateral forces. As a result, the railroad developed two prototype electric locomotive designs, a rigid frame class R1 2-D-2 and an articulated frame class GG1 2-C+C-2. Follow-up track testing verified that the GG1 had lower track lateral forces, and was selected for production. The 4,620 hp GG1 combined several significant North American design concepts: - Exceptional power from six double-armature traction motors for heavy passenger train operation at 100 mph; - Double-ended body design to eliminate the need to turn locomotives; - Use of separate truck frames with an articulation joint connection, allowing improved rail tracking and lower lateral forces; - Housing the main transformer and locomotive cabs in the center body, providing increased crew accident protection in collisions; - Use of high voltage Alternating Current (11 kV at 25 Hz); and - One of the first applications of Industrial Design (by Donald R. Dohner and Raymond F. Loewy) producing a streamlined locomotive using a welded carbody. The GG1 was quickly recognized as a rare combination of stellar performance, robust construction, and low maintenance costs. It was used to inaugurate electrified New York-Washington operations, performed admirably during World War II, successfully made the later transition to freight train operation, and was finally retired in October 1983. The prototype GG1 locomotive 4800 has been designated an ASME national engineering landmark.
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Sun, Libin, Li Shi, Hongtao Wang, Haitao Wang, Yuqin Hu et Zhensheng Zhang. « Seismic Test and Analyses on Double-Layer Model of HTR-PM Graphite Structure ». Dans 2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icone20-power2012-54961.
Texte intégralRésumé :
This research is to investigate the feasibility and practicability of carrying out an experimental work to support the seismic assessment of High Temperature Reactor Pebble bed Module (HTR-PM) reactor graphite core structure, which contains thousands of graphite bricks and tens of thousands of keys/dowels. The seismic responses of HTR-PM reactor under the seismic and impact conditions are beyond the applicability of the analytical methods currently employed, and the experimental program would be required to enhance the development of alternative analytical method and extensions of the current methods. This work can provide information and judgments for potential future work that would be nuclear safety related. The seismic excitations applied on the 1:2 double-layer graphite core model without side and top metallic components support, which is part of HTR-PM side reflector structure, included: (a) the white noise excitation from 0.1g to 0.5g amplitude in two orthogonal directions; (b) sine-sweep, frequency band from 1.0 to 35.0 back to 1.0 Hz, sweep rates less than 2 oct/min while 1 oct/min around resonant frequencies, at constant 0.5g amplitude in one horizontal uniaxial excitation; (c) five OBEs (Operating Basis Earthquake) up to 7.4g and (d) one SSE (Safe Shutdown Earthquake) up to 8.0g by considering scale law; (e) Four similar models have been tested with different gaps (1.6, 3.0 and 5.0mm) between bricks and with/without holddown plates, which can indicate approximately core structure characteristic at different lifetime for graphite irradiation deformation. The response of acceleration and displacement are measured in the tests. The natural frequencies of double layers model, bricks radial and tangential relative displacement have been calculated from the test results. Damaged graphite components have been counted and analyzed. The purpose of the test is to (a) investigate model dynamic behavior and response characteristics of integrated graphite components, (b) verify model scaling laws; (b) provide specific data on bricks relative displacement, acceleration; (c) provide data for correlation with analytical models; (d) verify the seismic analysis code to be developed in INET, and (e) optimize the detail design for HTR-PM project. The preliminary simulation results achieved good agreement with the data obtained from the test.
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Ourives, Eliete Auxiliadora, Attilio Bolivar Ourives de Figueiredo, Luiz Fernando Gonçalves de Figueiredo, Milton Luiz Horn Vieira, Isabel Cristina Victoria Moreira et Francisco Gómez Castro. « A IMPORTÂNCIA DA ABORDAGEM SISTÊMICA NA ERGONOMIA PARA UM DESIGN FUNCIONAL ». Dans Systems & Design 2017. Valencia : Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/sd2017.2017.6648.
Texte intégralRésumé :
RESUMO A abordagem sistêmica é um processo interdisciplinar, cujo princípio primordial é compreender a interdependência recíproca e relações de todas as áreas e da necessidade de sua integração, permitindo maior aproximação entre os seus limites de estudo. Nesse contexto o olhar sistêmico, da ergonomia, sobretudo no que se refere à segurança, ao conforto e à eficácia de uso, de funcionalidade e de operacionalidade dos objetos, considerando todos os produtos ou sistemas de produtos, como sistema de uso, desde os mais simples aos mais complexos ou sistêmicos, tem como objetivo adequá-los aos seres humanos, tendo em vista as atividades e tarefas exercidas por eles. No que se refere ao design funcional, os conhecimentos da ergonomia, nessa visão sistêmica, relativos à sua metodologia de projeto, são absolutamente necessários, e a sua aplicação aponta a melhor adequação dos produtos aos seus usuários. Como é o caso do vestuário feminino funcional, sobretudo no que se refere a proteção das mamas, que são peças convencionais que necessitam de um correto dimensionamento e especificação dos tecidos e de outros materiais. É um tipo de vestuário que apresenta funcionalidade diversa, como para a proteção física, o aumento do volume da mama, enchimento no bojo de pano, de água, de óleo, estruturado com arame, etc.; para amamentação (sutiã que se abre na frente, em parte ou totalmente); para o design inclusivo (pessoas com deficiência e mobilidade reduzida, no caso de mamas com prótese ou órtese) facilitando com fechamentos e aberturas colocadas em peças de roupas difíceis de manusear, roupas confortáveis e fáceis de vestir. São peças usadas por pessoas com biótipos e percentis antropométricos variáveis e com características corporais que mudam significativamente nas passagens para a adolescência, idade adulta e idosa. As mudanças corporais apresentam diferenças significativas em termos de volume das mamas, nas quais as soluções ergonômicas por uma abordagem sistêmicas que se evidencia mais para a complexidade de uso, são as mais necessárias em termos de atributos como, segurança, conforto, comodidade corporal, facilidade do vestir, funcionalidade, além da estética. Esta pesquisa, embora exploratória e descritiva, não isenta de desafios, tem por objetivo, por meio de dados e informações ergonômicas sistêmicas contribuir com o design funcional, de modo a oferecer subsídios para a confecção de roupas funcionais ou tecnologia vestível, com os atributos citados, respeitando a diversidade e inclusão das pessoas em todas as fases de sua vida, atendendo assim os princípios formais do design. Palavra-chave: Abordagem sistêmica, Ergonomia, Design funcional. REFERENCIAS AROS, Kammiri Corinaldesi. Elicitação do processo projetual do Núcleo de Abordagem Sistêmica do Design da Universidade Federal de Santa Catarina. Orientador: Luiz Fernando Gonçalves de Figueiredo – Florianópolis, SC, 2016. BERTALANFFY, Ludwig V. Teoria geral dos sistemas: fundamentos, desenvolvimento e aplicações. 3. ed. Petrópolis, RJ: Vozes, 2008. BEST, Kathryn. Fundamentos de gestão do design. Porto Alegre: Bookman, 2012. 208 p. CHIAVENATO, I. Gestão de pessoas. 3ª ed. Rio de Janeiro: Elsevier, 2010. CORRÊA, Vanderlei Moraes; BOLETTI, Rosane Rosner. Ergonomia: fundamentos e aplicações. Bookman Editora, 2015.MERINO, Eugenio. Fundamentos da ergonomia. 2011. Disponível em: <https://moodle.ufsc.br/pluginfile.php/2034406/mod_resource/content/1/Ergo_Fundamentos.pdf>. Acesso em: 24 Mar 2017. DIAS E. C. Condições de vida, trabalho, saúde e doença dos trabalhadores rurais no Brasil. In: Pinheiro TMM, organizador. Saúde do trabalhador rural –RENAST. Brasília: Ministério da Saúde; 2006.p. 1-27. GIL, A. C. Como elaborar projetos de pesquisa. 4. ed. São Paulo: Atlas, 2010. GOMES FILHO, J. Ergonomia do objeto: sistema técnico de leitura ergonômica. São Paulo: Escrituras Editora, 2003. GUIMARÃES, L. B. M. (ed). Ergonomia de Processo. Porto Alegre, v.2, PPGE/UFRGS, 2000. IIDA, I. Ergonomia: projeto e produção. 2ª ed rev. e ampl. – São Paulo: Edgard Blucher, 2005. MANZINI, Ezio. Design para inovação social e sustentabilidade: comunidades criativas, organizações colaborativas e novas redes projetuais. Rio de Janeiro: E-Papers, 2008, 104p. MARCONI, M. A.; Lakatos, E. M. Fundamentos de metodologia científica. São Paulo: Atlas, 2007. Pandarum, R., Yu, W., and Hunter, L., 2011. 3-D breast anthropometry of plus-sized women in South Africa. Ergonomics, 54(9), 866–875. McGhee, D.E., Steele, J.R., and Munro, B.J., 2008. Sports bra fitness. Wollongong (NSW): Breast Research Australia. McGhee, D.E., Steele, J.R., and Munro, B.J., 2010. Education improves bra knowledge and fit, and level of breast support in adolescent female athletes: a cluster-randomised trial. Journal of Physiotherapy, 56, 19–24. Pechter, E.A., 1998. A new method for determining bra size and predicting postaugmentation breast size. Plastic and Reconstructive Surgery, 102 (4), 1259–1265. RICHARDSON, R. J. Pesquisa social: métodos e técnicas. 3 ed. São Paulo: Atlas, 2008. RIO, R. P. DO; PIRES, L. Ergonomia: fundamentos da prática ergonômica, 3ª Ed., Editora LTr, 2001. SANTOS, N. ET AL. Antropotecnologia: A Ergonomia dos sistemas de Produção. Curitiba: Gênesis, 1997. VASCONCELLOS, Maria José Esteves de. Pensamento sistêmico: O novo paradigma da ciência. 10ª ed. Campinas, SP: Papirus, 2013. WEERDMEESTER, J. D. e B. Ergonomia Prática. São Paulo: Edgard Blucher, 2001. WHITE, J.; SCURR, J. Evaluation of professional bra fitting criteria for bra selection and fitting in the UK. Ergonomics, 1–8. 2012. WHITE, J.;SCURR, J.; SMITH, N. The effect of breast support on kinetics during overground running performance. Ergonomics, Taylor & Francis. 52 (4), 492–498. 2009.