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Articoli di riviste sul tema "AIDS (Disease) and art"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 agosto 2024

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1

Hull-Nye, Dylan, Bhawna Malik, Ravikiran Keshavamurthy, and Elissa J. Schwartz. "Transient dynamics of the renal disease epidemic among HIV-infected individuals." Mathematics in Applied Sciences and Engineering 9999, no. 9999 (December 24, 2020): 1–10. http://dx.doi.org/10.5206/mase/10852.

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The prevalence of end stage renal disease (ESRD) is rising among HIV-infected populations in several regions worldwide. We used an ordinary differential equation model of the dynamics of the AIDS and HIV+ ESRD populations to investigate the effect of antiretroviral therapy (ART) on the transient dynamics of the epidemic. We considered ART that blocks the entry to each population, by preventing individuals from joining the AIDS population and by reducing the development from AIDS to HIV+ ESRD, as well as the combined effects together. Numerical simulation of our model revealed that when levels

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Hou, Keke, Hang Fu, Wei Xiong, Yueqin Gao, Liqiu Xie, Jianglin He, Xianbiao Feng, et al. "Clinical Application of Cardiac Magnetic Resonance in ART-Treated AIDS Males with Short Disease Duration." Diagnostics 12, no. 10 (October 6, 2022): 2417. http://dx.doi.org/10.3390/diagnostics12102417.

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Cardiac complications are common in antiretroviral therapy-treated (ART-treated) acquired immune deficiency syndrome (AIDS) patients, and the incidence increases with age. Myocardial injury in ART-treated AIDS patients with a relatively longer disease duration has been evaluated. However, there is no relevant study on whether patients with a short AIDS duration have cardiac dysfunction. Thirty-seven ART-treated males with AIDS and eighteen healthy controls (HCs) were prospectively included for CMR scanning. Clinical data and laboratory examination results were collected. The ART-treated males

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Burki, Talha. "AIDS activism through art." Lancet HIV 9, no. 11 (November 2022): e749-e750. http://dx.doi.org/10.1016/s2352-3018(22)00307-1.

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Kuhlman, Janet E. "Imaging pulmonary disease in AIDS: state of the Art." European Radiology 9, no. 3 (March 1999): 395–408. http://dx.doi.org/10.1007/s003300050682.

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Ara, Takahide, Tomoyuki Endo, Hideki Goto, Kohei Kasahara, Yuta Hasegawa, Shota Yokoyama, Souichi Shiratori, et al. "Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor." Antiviral Therapy 27, no. 5 (September 13, 2022): 135965352211268. http://dx.doi.org/10.1177/13596535221126828.

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Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor which occurs in immunocompromised patients. The immune status is an important factor in the treatment of EBV-SMTs, but the efficacy of antiretroviral therapy (ART) is not elucidated in acquired immune deficiency syndrome (AIDS) related EBV-SMTs. Here, we report the first successful case of a 29-year-old man with hepatic AIDS related EBV-SMT treated with ART solely. Positron emission tomography scan was useful for the evaluation of disease status. Recent advances in ART that enables to restore patient’s immu

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Memish, Ziad A., Jaffar A. Al-Tawfiq, Sanaa M. Filemban, Syed Qutb, Abdullah Fodail, Batol Ali, and May Darweeish. "Antiretroviral therapy, CD4, viral load, and disease stage in HIV patients in Saudi Arabia: a 2001–2013 cross-sectional study." Journal of Infection in Developing Countries 9, no. 07 (July 30, 2015): 765–69. http://dx.doi.org/10.3855/jidc.6588.

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Introduction: The incidence of HIV/AIDS is increasing worldwide and in the Middle East. In this study, we analyzed the use of antiretroviral therapy (ART), the patterns of CD4 and viral load (VL), and stage of presentation. Methodology: Laboratory variables, ART use, and CD4 count were obtained and analyzed retrospectively. Results: A total of 997 cases from eight HIV/AIDS care providers were included. Of the total cases, 274 (28.3%) had a CD4 count of < 200 cells/mm3, and 413 (42.3%) had a viral load of > 5 log10. Of the total cases, 50% were on highly active antiretroviral therapy (HAA

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Houle, Brian, Chodziwadziwa Kabudula, Sanyu A. Mojola, Nicole Angotti, Francesc Xavier Gómez-Olivé, Dickman Gareta, Kobus Herbst, Samuel J. Clark, Jane Menken, and Vladimir Canudas-Romo. "Mortality variability and differentials by age and causes of death in rural South Africa, 1994–2018." BMJ Global Health 9, no. 4 (April 2024): e013539. http://dx.doi.org/10.1136/bmjgh-2023-013539.

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IntroductionUnderstanding mortality variability by age and cause is critical to identifying intervention and prevention actions to support disadvantaged populations. We assessed mortality changes in two rural South African populations over 25 years covering pre-AIDS and peak AIDS epidemic and subsequent antiretroviral therapy (ART) availability.MethodsUsing population surveillance data from the Agincourt Health and Socio-Demographic Surveillance System (AHDSS; 1994–2018) and Africa Health Research Institute (AHRI; 2000–2018) for 5-year periods, we calculated life expectancy from birth to age 8

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Olowookere, Samuel Anu, Akinola Ayoola Fatiregun, and Isaac F. Adewole. "Knowledge and attitudes regarding HIV/AIDS and antiretroviral therapy among patients at a Nigerian treatment clinic." Journal of Infection in Developing Countries 6, no. 11 (November 26, 2012): 809–16. http://dx.doi.org/10.3855/jidc.2086.

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Introduction: We assessed the knowledge of and attitudes toward HIV/AIDS and antiretroviral therapy (ART) in people living with HIV/AIDS (PLWHA). Methodology: A descriptive, cross-sectional study design was employed. A structured interviewer-administered questionnaire was administered to consecutive, consenting PLWHA who had been receiving treatment for a minimum of three months. The level of ART adherence was calculated manually for each respondent. Results: In total 318 PLWHA completed the questionnaire. The mean and median time on ART was 17.8 months and 19 months respectively. The mean age

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Kumar, Vinod. "ART in HIV/AIDS Adults and Adolescents." Current Research in Medical Sciences 2, no. 4 (December 2023): 68–84. http://dx.doi.org/10.56397/crms.2023.12.09.

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There has been a rapid decline in HIV-related mortality and morbidity due to the wider availability of affordable, more efficacious and less toxic ARVs over the last two decades. ART consists of the use of a combination of at least three ARV drugs from different classes to inhibit the replication of HIV and reduce viraemia to undetectable levels. Continued suppression of viral replication leads to the restoration of immune response, reflected by an increase in the CD4 count. Increase in CD4 count leads to slowing of the disease progression, reduced frequency of OIs, improvement in the quality

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Davis, Ms Bob. "Glamour, Drag, and Death." TSQ: Transgender Studies Quarterly 8, no. 1 (February 1, 2021): 113–20. http://dx.doi.org/10.1215/23289252-8749638.

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Abstract In the art of three San Francisco drag queen painters we find their highly personal responses to HIV/AIDS and their own mortality. Doris Fish's commitment to glamour wouldn't allow the disease to intrude on her paintings, though she was able to write about her illness's progress in her weekly newspaper column. Jerome Caja made art from the disease's horror by incorporating the ashes of deceased artist Charles Sexton, who died of AIDS, into her works, her way of mastering the carnage. Miss Kitty confronted the disease in an even more personal way, creating art from her own illness by i

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Ofosu, Nicole Naadu, L. Duncan Saunders, Gian Jhangri, and Afif Alibhai. "The impact of the availability of antiretroviral therapy on personal and community fear of HIV/AIDS, and HIV prevention practices in Rwimi, Uganda: A mixed-method study." Alberta Academic Review 1, no. 1 (May 28, 2018): 1–14. http://dx.doi.org/10.29173/aar11.

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The impact of the widespread availability of antiretroviral therapy (ART) on the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) related attitudes, behaviours and practices of the general population in Sub-Saharan Africa is understudied. We assessed the impact of ART availability on the fear of HIV/ AIDS (measured at both community and personal levels) and HIV prevention practices in Rwimi, Uganda using a cross-sectional survey. The fear of HIV/AIDS was described as a perceived threat to either self and/or community regarding the risk of contracting the disease,

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Shield, Kevin David, Paul A. Shuper, Gerrit Gmel, and Jürgen Rehm. "Global burden of HIV/AIDS in 2004 resulting from alcohol attributable non-adherence to medication regimes." International Journal of Alcohol and Drug Research 2, no. 1 (March 4, 2013): 19–44. http://dx.doi.org/10.7895/ijadr.v2i1.52.

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Shield, K. D., Shuper, P. A., Gmel, G. & Rehm, J. (2013). Global burden of HIV/AIDS in 2004 resulting from non-adherence to medication regimes and alcohol-attributable non-adherence to medication regimes. International Journal of Alcohol and Drug Research, 2(1), 19-44. doi: 10.7895/ijadr.v2i1.52 (http://dx.doi.org/10.7895/ijadr.v2i1.52)Aims: Using novel methodology, this article aims to quantify the number of HIV/AIDS-related deaths and the potential years of life lost (PYLL) in 2004 resulting from non-adherence to antiretroviral treatment (ART) and non-adherence to ART due to alcohol cons

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ABBASI, RI, JH SHAIKH, B. GHAFAR, R. ZAREEN, T. ZAFAR, and A. KUMAR. "RETROSPECTIVE STUDY OF THE IMPACT OF ANTIRETROVIRAL THERAPY ON HIV/AIDS MORTALITY RATES." Biological and Clinical Sciences Research Journal 2023, no. 1 (June 27, 2023): 369. http://dx.doi.org/10.54112/bcsrj.v2023i1.369.

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Antiretroviral therapy (ART) has transformed HIV/AIDS from a fatal disease to a manageable chronic condition. The correlation between adherence to ART regimens, immunological and virological markers, and mortality rates among patients with HIV/AIDS necessitates ongoing research. In this retrospective study, we reviewed the medical records of 120 HIV/AIDS patients treated with ART at a tertiary care center. We categorized patients into five ART regimens, assessed reported adherence, and analyzed the corresponding immunological and virological parameters. Furthermore, we evaluated the impact of

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Junge, Sophie. "Art Is Still Not Enough. Bilder von AIDS im Spannungsfeld zwischen Kunstanspruch und politischer Mobilisierung." Zeitschrift für Kunstgeschichte 79, no. 2 (December 30, 2016): 261–75. http://dx.doi.org/10.1515/zkg-2016-0020.

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Abstract The paper examines the reception of HIV/AIDS-related artworks from the 1980s by comparing four New York exhibitions from the early 1990s and 2010s. It argues that to this day artworks dealing with AIDS are bound to political and moral demands of former activists from the AIDS movement in New York. This politicization of historical images of AIDS is striking since the disease has lost its fatal threat in Western countries and political constellations have changed. Yet current exhibitions focus only on activist, politically motivated responses to the epidemic in order to represent an “a

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Rajasekar, V., D. Thirunaaukarasu, and R. Surendar. "Socio-Demographic Profile and Adherence to Anti-Retroviral Treatment among HIV/AIDS Patients Attending the ART Centre in Tamil Nadu." Journal of Medical Sciences and Health 9, no. 2 (October 31, 2023): 163–68. http://dx.doi.org/10.46347/jmsh.v9i2.23.403.

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Background: Epidemiology of HIV infection in India is varied and depends on multitude of factors such as socio-demographic profile, geographic location and behavioural pattern. HIV/AIDS is not only a public health issue in India but also one of the most serious socioeconomic and developmental concerns as nearly 86% of reported cases occur in sexually active and economically productive age group (15-49yrs). Thus, for planning targeted interventions, it is essential to know the socio-demographic and clinical profile of the HIV/AIDS patients in a particular area as important for control of HIV re

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Gupta, P. K., S. Tyagi, S. E. Mathews, R. Saini, H. Sesama, A. Chugh, K. Singh, and M. P. S. Chawla. "Non-Alcoholic fatty liver disease and metabolic syndrome in patients with HIV/AIDS and its correlation with antiretroviral therapy and severity of disease." Sri Lanka Journal of Medicine 32, no. 1 (August 17, 2023): 18–25. http://dx.doi.org/10.4038/sljm.v32i1.348.

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Introduction: Metabolic syndrome (MetS) and Non-alcoholic fatty liver disease (NAFLD) are two major causes of morbidity in chronic HIV infected patients on antiretroviral therapy (ART). This study was done on HIV infected individuals by comparing ART naive patients with patients on different ART regimens and evaluating the effect of ART on Metabolic syndrome and NAFLD.Method: It was a cross-sectional observational study done on 120 HIV infected individuals in a tertiary care centre in New Delhi. All cases with hypertension, diabetes, chronic kidney or liver disease, thyroid disorders or on any

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Mirahmadizadeh, Alireza, Mehdi Sharafi, Jafar Hassanzadeh, Mozhgan Seif, and Alireza Heiran. "Effectiveness of Antiretroviral Treatment on the Transition Probability of Immunological State of HIV/AIDS Patients: A Markov Chain Model on the Iranian “National Registry of HIV/AIDS Care” Database." BioMed Research International 2023 (April 12, 2023): 1–7. http://dx.doi.org/10.1155/2023/1989983.

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Antiretroviral therapy (ART) has improved survival and clinical course amongst HIV/AIDS patients. CD4 cell count is one of the most critical indicators of the disease progression. With respect to the dynamic nature of CD4 cell count during the clinical history of HIV/AIDS, modeling the CD4 cell count changes, which represents the likelihood of disease progression, is of interest to establish or revise treatment strategies and, specifically, to determine the stage at which giving ART is more clinically effective. In this historical cohort study on 917 HIV/AIDS patients in the Iranian “National

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Salem, Benissa E., Yvita Bustos, Chidyaonga Shalita, Jordan Kwon, Padma Ramakrishnan, Kartik Yadav, Maria L. Ekstrand, Sanjeev Sinha, and Adeline M. Nyamathi. "Chronic Disease Self-Management Challenges among Rural Women Living with HIV/AIDS in Prakasam, Andhra Pradesh, India: A Qualitative Study." Journal of the International Association of Providers of AIDS Care (JIAPAC) 17 (January 1, 2018): 232595821877376. http://dx.doi.org/10.1177/2325958218773768.

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Rural women living with HIV/AIDS (WLHA) in India experience challenges self-managing HIV/AIDS in their rural communities. The purpose of this qualitative study was to explore factors influencing their care and antiretroviral treatment (ART) adherence. Themes that emerged from the qualitative focus groups among WLHA (N = 24) in rural Prakasam, Andhra Pradesh, India, included: (1) coming to know about HIV and other health conditions, (2) experiences being on ART, (3) challenges maintaining a nutritious diet, (4) factors affecting health care access and quality, and (5) seeking support for a bett

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Trickey, Adam, Robert Glaubius, Nikos Pantazis, Robert Zangerle, Linda Wittkop, Janne Vehreschild, Sophie Grabar, et al. "Estimation of Improvements in Mortality in Spectrum Among Adults With HIV Receiving Antiretroviral Therapy in High-Income Countries." JAIDS Journal of Acquired Immune Deficiency Syndromes 95, no. 1S (January 1, 2024): e89-e96. http://dx.doi.org/10.1097/qai.0000000000003326.

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Introduction: Mortality rates for people living with HIV (PLHIV) on antiretroviral therapy (ART) in high-income countries continue to decline. We compared mortality rates among PLHIV on ART in Europe for 2016–2020 with Spectrum's estimates. Methods: The AIDS Impact Module in Spectrum is a compartmental HIV epidemic model coupled with a demographic population projection model. We used national Spectrum projections developed for the 2022 HIV estimates round to calculate mortality rates among PLHIV on ART, adjusting to the age/country distribution of PLHIV starting ART from 1996 to 2020 in the An

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Dunn, Robert, Roopam Jariwal, Frederick Venter, Shikha Mishra, Janpreet Bhandohal, Everado Cobos, and Arash Heidari. "HHV-8-Associated Multicentric Castleman Disease, a Diagnostic Challenge in a Patient With Acquired Immunodeficiency Syndrome and Fever." Journal of Investigative Medicine High Impact Case Reports 10 (January 2022): 232470962210975. http://dx.doi.org/10.1177/23247096221097526.

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Patients with acquired immunodeficiency syndrome (AIDS) are at an increased susceptibility to pathogens and associated malignancies which can present with a unique constellation of symptoms. In this article, we describe a case of Castleman disease in a patient with AIDS, nonadherent with antiretroviral therapy (ART), who presented with fevers, constant abdominal pain, nausea, and vomiting. After an extensive work up, a lymph node biopsy confirmed a diagnosis of human herpesvirus-8 (HHV-8)-associated multicentric Castleman disease. Patients presenting with AIDS and fever have broad differential

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Martinez, S. S., A. Campa, H. Bussmann, S. Moyo, J. Makhema, F. G. Huffman, O. D. Williams, M. Essex, R. Marlink, and M. K. Baum. "Effect of BMI and fat mass on HIV disease progression in HIV-infected, antiretroviral treatment-naïve adults in Botswana." British Journal of Nutrition 115, no. 12 (April 18, 2016): 2114–21. http://dx.doi.org/10.1017/s0007114516001409.

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AbstractAn obesity paradox has been proposed in many conditions including HIV. Studies conducted to investigate obesity and its effect on HIV disease progression have been inconclusive and are lacking for African settings. This study investigated the relationship between overweight/obesity (BMI≥25 kg/m2) and HIV disease progression in HIV+ asymptomatic adults not on antiretroviral treatment (ART) in Botswana over 18 months. A cohort study in asymptomatic, ART-naïve, HIV+ adults included 217 participants, 139 with BMI of 18·0–24·9 kg/m2 and seventy-eight participants with BMI≥25 kg/m2. The prim

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Dankwa-Mullan, Irene, M. Christopher Roebuck, Joseph Tkacz, Oluwadamilola Motunrayo Fayanju, Yi Ren, Gretchen Purcell Jackson, and Yull Edwin Arriaga. "Disparities in receipt of and time to adjuvant therapy after lumpectomy." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): 534. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.534.

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534 Background: Adjuvant treatment after breast conserving surgery (BCS) has been shown to improve outcomes, but the degree of uptake varies considerably. We sought to examine factors associated with post-BCS receipt of and time to treatment (TTT) for adjuvant radiation therapy (ART), cytotoxic chemotherapy (ACT) and endocrine therapy (AET) among women with breast cancer. Methods: IBM MarketScan claims data were used to select women diagnosed with non-metastatic invasive breast cancer from 01/01/2012 to 03/31/2018, who received primary BCS without any neoadjuvant therapy, and who had continuou

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Bushaku, Marcus, Caleb Nyamwange, Arthur Kwena, Marc Twagirumukiza, Jean Nepo Utumatwishima, Regine Mugeni, Victor Davila-Roman, et al. "Detection of Undiagnosed Elevated Cardiovascular Risk Biomarkers among HIV-Positive Patients on Antiretroviral Therapy (ART) in Kigali-City, Rwanda." Journal of AIDS and HIV Treatment 5, no. 1 (May 23, 2023): 13–21. http://dx.doi.org/10.33696/aids.5.042.

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Background: Similar to other African countries, life expectancy of people living with HIV infection has improved due to access to antiretroviral therapy (ART) in Rwanda. However, both HIV infection and use of ART are associated with cardiovascular disease (CVD) risks, due to adverse changes in some biomarkers, causing dyslipidemia and other metabolic imbalances. Biomarkers for CVD risk in HIV-infected individuals taking ART, has not been well characterized in Rwanda. We evaluated the association between the use and duration of ART and biomarkers of CVD risk among HIV infected adults in Rwanda.

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Goswami, Neela D., Jonathan Colasanti, Jonathan J. Khoubian, Yijian Huang, Wendy S. Armstrong, and Carlos del Rio. "A Minority of Patients Newly Diagnosed with AIDS Are Started on Antiretroviral Therapy at the Time of Diagnosis in a Large Public Hospital in the Southeastern United States." Journal of the International Association of Providers of AIDS Care (JIAPAC) 16, no. 2 (February 15, 2017): 174–79. http://dx.doi.org/10.1177/2325957417692679.

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Prompt antiretroviral therapy (ART) initiation after AIDS diagnosis, in the absence of certain opportunistic infections such as tuberculosis and cryptococcal meningitis, delays disease progression and death, but system barriers to inpatient ART initiation at large hospitals in the era of modern ART have been less studied. We reviewed hospitalizations for persons newly diagnosed with AIDS at Grady Memorial Hospital in Atlanta, Georgia in 2011 and 2012. Individual- and system-level variables were collected. Logistic regression models were used to estimate the odds ratios (ORs) for ART initiation

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Chen, Mingyu, Cong Liu, Jinzhao Xie, Xiaoping Tang, Yao Zhang, Deng Pan, Haidan Zhong, et al. "Effectiveness of integrase strand transfer inhibitors among treatment-naive people living with HIV/AIDS in Guangdong, China: A real-world, retrospective cohort study." Medicine 103, no. 23 (June 7, 2024): e38497. http://dx.doi.org/10.1097/md.0000000000038497.

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Integrase strand transfer inhibitors (INSTIs) in anti-retroviral therapy (ART) have been recommended by the World Health Organization for their higher efficacy, favorable safety and tolerability. However, the clinical evidence supporting switching to INSTI-containing regimens in low-and-middle-income countries (LMICs) is limited, as few patients have access to these regimens. We aimed to assess the effectiveness of INSTI-containing regimens in real-world settings in China compared to government-provided free ART. We compared the short-term (first 4 mo following ART initiation) and long-term (1

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McManus, Kathleen A., Carolyn L. Engelhard, and Rebecca Dillingham. "Current Challenges to the United States’ AIDS Drug Assistance Program and Possible Implications of the Affordable Care Act." AIDS Research and Treatment 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/350169.

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AIDS Drug Assistance Programs, enacted through the Ryan White Comprehensive AIDS Resources Emergency Act of 1990, are the “payer of last resort” for prescription medications for lower income, uninsured, or underinsured people living with HIV/AIDS. ADAPs face declining funding from the federal government. State funding of ADAP is discretionary, but some states increased their contributions to meet the gap in funding. The demand for ADAP support is increasing as people living with HIV are living longer; the antiretroviral therapy (ART) guidelines have been changed to recommend initiation of trea

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Oladele, Rita, Folasade Ogunsola, Alani Akanmu, Katie Stocking, David W Denning, and Nelesh Govender. "Opportunistic fungal infections in persons living with advanced HIV disease in Lagos, Nigeria; a 12-year retrospective study." African Health Sciences 20, no. 4 (December 16, 2020): 1573–81. http://dx.doi.org/10.4314/ahs.v20i4.9.

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Introduction: Nigeria has a large estimated burden of AIDS-related mycoses. We aimed to determine the proportion of pa- tients with AIDS-related opportunistic fungal infections (OFIs) at an urban antiretroviral treatment (ART) centre in Nigeria. Methods: A retrospective analysis of a cohort of ART-naïve, HIV-infected patients, assessed for ART eligibility and ART- experience at the PEPFAR outpatient clinic at Lagos University Teaching Hospital over a 12-year period (April 2004-Feb- ruary 2016) was conducted. Results: During this period, 7,034 patients visited the clinic: 4,797 (68.

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Ogoina, Dimie, Reginald O. Obiako, Haruna M. Muktar, Mukhtar Adeiza, Aliyu Babadoko, Abdulaziz Hassan, Isa Bansi, Henry Iheonye, Matthew Iyanda, and Eric Tabi-Ajayi. "Morbidity and Mortality Patterns of Hospitalised Adult HIV/AIDS Patients in the Era of Highly Active Antiretroviral Therapy: A 4-year Retrospective Review from Zaria, Northern Nigeria." AIDS Research and Treatment 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/940580.

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Background. This study, undertaken in major tertiary hospital in northern Nigeria, examined the morbidity and mortality patterns of hospitalised adult HIV/AIDS patients in the HAART era.Methods. Between January 2006 and December 2009, admission records and causes of deaths of hospitalised medical HIV-infected patients were retrieved and analysed according to antiretroviral (ART) status.Results. Of the 207 HIV/AIDS patients reviewed, majority were newly diagnosed (73.4%), and most were hospitalised and died from various AIDS-defining illnesses, mainly disseminated tuberculosis and sepsis. Immun

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Hoenigl, Martin, Carlee B. Moser, Nicholas Funderburg, Ronald Bosch, Amy Kantor, Yonglong Zhang, Jesper Eugen-Olsen, et al. "Soluble Urokinase Plasminogen Activator Receptor Is Predictive of Non-AIDS Events During Antiretroviral Therapy–mediated Viral Suppression." Clinical Infectious Diseases 69, no. 4 (November 12, 2018): 676–86. http://dx.doi.org/10.1093/cid/ciy966.

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Abstract Background Despite effective antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains associated with higher morbidity and mortality, driven, in part, by increased inflammation. Our objective was to identify associations between levels of plasma biomarkers of chronic inflammation, microbial translocation, and monocyte activation, with occurrence of non-AIDS events. Methods Participants (141 cases, 310 matched controls) were selected from a longitudinal observational trial; all were virally suppressed on ART at year 1 and thereafter. Soluble urokinase plasmino

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Bussmann, Christine, Philip Rotz, Ndwapi Ndwapi, Daniel Baxter, Hermann Bussmann, C. William Wester, Patricia Ncube, et al. "Strengthening Healthcare Capacity Through a Responsive, Country-Specific, Training Standard: The KITSO AIDS Training Program’s Sup-port of Botswana’s National Antiretroviral Therapy Rollout." Open AIDS Journal 2, no. 1 (February 29, 2008): 10–16. http://dx.doi.org/10.2174/1874613600802010010.

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In parallel with the rollout of Botswana’s national antiretroviral therapy (ART) program, the Botswana Ministry of Health established the KITSO AIDS Training Program by entering into long-term partnerships with the Botswana–Harvard AIDS Institute Partnership for HIV Research and Education and others to provide standardized, country-specific training in HIV/AIDS care. The KITSO training model has strengthened human capacity within Botswana’s health sector and been indispensable to successful ART rollout. Through core and advanced training courses and clinical mentoring, different cadres of heal

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Mathews, Sujata E., Dinesh Srivastava, Raj Bala Yadav, and Anjali Sharma. "Association of Hematological Profile of Human Immunodeficiency Virus-Positive Patients with Clinicoimmunologic Stages of the Disease." Journal of Laboratory Physicians 5, no. 01 (January 2013): 34–37. http://dx.doi.org/10.4103/0974-2727.115929.

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ABSTRACT Aim: This work was carried out to study the hematologic profile of human immunodeficiency virus (HIV)-positive patients and its association with the clinicoimmunologic stage of the disease. Materials and Methods: A total of 187 patients with HIV, whether symptomatic or asymptomatic, diagnosed by enzyme-linked immunosorbent assay (ELISA) method according to the National AIDS Control Organization (NACO) guidelines were included in this study. Patients in the study population were divided into two groups: (1) Group A (antiretroviral therapy (ART) included patients receiving ART [ART-Y])

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Chammartin, Frédérique, Cam Ha Dao Ostinelli, Kathryn Anastos, Antoine Jaquet, Ellen Brazier, Steven Brown, Francois Dabis, et al. "International epidemiology databases to evaluate AIDS (IeDEA) in sub-Saharan Africa, 2012–2019." BMJ Open 10, no. 5 (May 2020): e035246. http://dx.doi.org/10.1136/bmjopen-2019-035246.

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PurposeThe objectives of the International epidemiology databases to evaluate AIDS (IeDEA) are to (i) evaluate the delivery of combination antiretroviral therapy (ART) in children, adolescents and adults in sub-Saharan Africa, (ii) to describe ART regimen effectiveness, durability and tolerability, (iii) to examine HIV-related comorbidities and coinfections and (iv) to examine the pregnancy-related and HIV-related outcomes of women on ART and their infants exposed to HIV or ART in utero or via breast milk.ParticipantsIeDEA is organised in four regions (Central, East, Southern and West Africa),

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Peer, Nazia, Isaac I. Bogoch, Quique Bassat, Leslie Newcombe, Leah K. Watson, Nico Nagelkerke, and Prabhat Jha. "AIDS-defining causes of death from autopsy findings for HIV-positive individuals in sub-Saharan Africa in the pre- and post-ART era: A systematic review and meta-analyses." Gates Open Research 3 (July 17, 2019): 1509. http://dx.doi.org/10.12688/gatesopenres.13041.1.

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Background: The lack of representative data on causes of death in sub-Saharan Africa (SSA) hampers our understanding of the regional burden of HIV and impact of interventions. In spite of the roll-out of antiretroviral therapy (ART) programs, HIV-infected individuals are still dying from complications of AIDS in SSA. We reviewed autopsy findings in SSA to observe whether the prevalence of 14 AIDS-defining illnesses changed from the pre-ART era to the post-ART era. Methods: We conducted a systematic review of autopsy findings in SSA using Medline, CINAHL, Evidence Based Medicine, EMBASE, Scopus

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Spano, Jean-Philippe, Dominique Costagliola, Christine Katlama, Nicolas Mounier, Eric Oksenhendler, and David Khayat. "AIDS-Related Malignancies: State of the Art and Therapeutic Challenges." Journal of Clinical Oncology 26, no. 29 (October 10, 2008): 4834–42. http://dx.doi.org/10.1200/jco.2008.16.8252.

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Despite the impact of combination antiretroviral therapy (cART) on HIV-related mortality, malignancy remains an important cause of death in the current era. Although the advent of cART has resulted in reductions in the incidence of Kaposi's sarcoma and non-Hodgkin's lymphoma, non–AIDS-defining malignancies present an increased risk for HIV-infected patients, characterized by some common clinical features, generally with a more aggressive behavior and a more advanced disease at diagnosis, which is responsible for poorer patient outcomes. Specific therapeutic recommendations are lacking for thes

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Bang, Ajay, Deepti Deshmukh, and Sanjay Raut. "A STUDY OF CARDIAC MANIFESTATIONS IN PATIENTS WITH HIV/AIDS." International Journal of Advanced Research 9, no. 10 (October 31, 2021): 411–22. http://dx.doi.org/10.21474/ijar01/13560.

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Introduction:HIV/AIDS pandemic is evolving as a major public concern. Cardiovascular diseases are common in HIV-positive patients. Many patients without any symptoms or signs were found to have a cardiovascular disease on autopsy.It is expected that the risk of cardiovascular disease willrise in the following years due to the cardiovascular risk profile andincreased life expectancy of infected patients. Therefore,diagnosis andtherapy of HIV-associated cardiovascular diseases should be part of the evaluation and management of the HIV-positive patient. Objectives: To find out the frequency of ca

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Ovcharuk, Daria, Isabel Jaszewski, and Dawid Porowski. "Septic Shock in the Course of Disseminated Tuberculosis in A COVID-19 Positive Patient with Concomitant AIDS." European Journal of Medical and Health Sciences 5, no. 2 (March 4, 2023): 1–4. http://dx.doi.org/10.24018/ejmed.2023.5.2.1562.

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A 23-year-old male patient presented to the Provincial Hospital for Infectious Diseases in Warsaw, Poland in February 2022 with severe septic shock in the course of COVID-19 infection. The patient’s history and physical exam indicated a suspicion of HIV, TB, and COVID-19 triple coinfection. Numerous ulcers and phlegmon were present on the lower limbs and back with the patient complaining of difficulty walking. Laboratory tests came back positive for COVID-19, saliva tests were positive for active tuberculosis, and blood test results for the CD4 count were < 200 cells/cubic millimeter confir

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Horner, Marie-Josèphe, Steady Chasimpha, Adrian Spoerri, Jessie Edwards, Julia Bohlius, Hannock Tweya, Petros Tembo, et al. "High Cancer Burden Among Antiretroviral Therapy Users in Malawi: A Record Linkage Study of Observational Human Immunodeficiency Virus Cohorts and Cancer Registry Data." Clinical Infectious Diseases 69, no. 5 (November 17, 2018): 829–35. http://dx.doi.org/10.1093/cid/ciy960.

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Abstract Background With antiretroviral therapy (ART), AIDS-defining cancer incidence has declined and non-AIDS–defining cancers (NADCs) are now more frequent among human immunodeficiency virus (HIV)–infected populations in high-income countries. In sub-Saharan Africa, limited epidemiological data describe cancer burden among ART users. Methods We used probabilistic algorithms to link cases from the population-based cancer registry with electronic medical records supporting ART delivery in Malawi’s 2 largest HIV cohorts from 2000–2010. Age-adjusted cancer incidence rates (IRs) and 95% confiden

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Kleinman, Adam J., Ivona Pandrea, and Cristian Apetrei. "So Pathogenic or So What?—A Brief Overview of SIV Pathogenesis with an Emphasis on Cure Research." Viruses 14, no. 1 (January 12, 2022): 135. http://dx.doi.org/10.3390/v14010135.

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HIV infection requires lifelong antiretroviral therapy (ART) to control disease progression. Although ART has greatly extended the life expectancy of persons living with HIV (PWH), PWH nonetheless suffer from an increase in AIDS-related and non-AIDS related comorbidities resulting from HIV pathogenesis. Thus, an HIV cure is imperative to improve the quality of life of PWH. In this review, we discuss the origins of various SIV strains utilized in cure and comorbidity research as well as their respective animal species used. We briefly detail the life cycle of HIV and describe the pathogenesis o

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Veras, Maria Amelia de Sousa Mascena, Manoel C. A. Ribeiro, Leda Fátima Jamal, Willi McFarland, Francisco Inácio Bastos, Karina Braga Ribeiro, Rita Barradas Barata, José Cassio de Moraes, and Arthur L. Reingold. "The "AMA-Brazil" cooperative project: a nation-wide assessment of the clinical and epidemiological profile of AIDS-related deaths in Brazil in the antiretroviral treatment era." Cadernos de Saúde Pública 27, suppl 1 (2011): s104—s113. http://dx.doi.org/10.1590/s0102-311x2011001300011.

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The objective of this study was to assess the profile of AIDS-related deaths in the post antiretroviral therapy (ART) scale up period in Brazil. A case-control study was conducted including a nationally probabilistic sample of AIDS deaths and living controls. Data were abstracted from medical records and nation-wide databases of AIDS cases, mortality, ART care, and laboratory testing. Interrupted (adjusted odds ratio - AOR 4.35, 95%CI: 3.15-6.00) or no use of ART (AOR 2.39, 95%CI: 1.57-3.65) was the strongest predictor of death, followed by late diagnosis (AOR 3.95, 95%CI: 2.68-5.82). Criterio

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Melani, Melani. "Prevalence and Factors Associated Depression or Depressive Symptoms in Patients with HIV/AIDS." Scientia Psychiatrica 4, no. 1 (August 25, 2021): 331–38. http://dx.doi.org/10.37275/scipsy.v4i1.82.

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HIV/AIDS is still a serious public health problem across the world. WHO reported that there were 37.7 million HIV positive patient in 2020. Patient HIV/AIDS are more prone to developing mental illnesses, including depression. Depression is more common in HIV-positive (HIV+) people than in HIV-negative (HIV-). The factor associated with depression in HIV/AIDS patients include age, gender, stigma, discrimination, social support, living alone, marital, educational, employment status, socioeconomic, the use of ART, CD4 count, and disease course. The high prevalence of depression and depressive sym

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Singh, Narendra, R. K. Varma, Richa Giri, Punit Varma, Seema Dwivedi, and Lalit Kumar. "Effect of ART 2 treatment on biochemical profile during treatment of second line ART." International Journal of Advances in Medicine 7, no. 5 (April 23, 2020): 777. http://dx.doi.org/10.18203/2349-3933.ijam20201610.

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Background: AIDS was the first recognized in U.S in summer of 1981 at centers for disease control and prevention reported the unexplained occurrence of pneumocystis jiroveci in previously healthy homosexual men in Los Angeles and Kaposi. First time in 1983 HIV syndrome was isolated from a patient of lymphadenopathy. Person with positive HIV serology who have ever had a CD4 lymphocyte count below 200celles/mcl and CD4 lymphocyte percentage below 14% are considered to have AIDS (CMDT 2017).Methods: This study was continuous longitudinal, prospective and retrospective, observational, at ART plus

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Jariyawattanarat, Vitvala, Somnuek Sungkanuparph, and Chutintorn Sriphrapradang. "CHARACTERISTICS OF GRAVES DISEASE IN HIV-INFECTED PATIENTS ON ANTIRETROVIRAL THERAPY." Endocrine Practice 26, no. 6 (June 2020): 612–18. http://dx.doi.org/10.4158/ep-2019-0514.

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Objective: To demonstrate clinical and laboratory characteristics of Graves disease in human immunodeficiency virus (HIV)-infected patients on antiretroviral therapy (ART). Methods: This is a single-institution study. All HIV-infected Thai patients who were diagnosed with Graves disease following the initiation of ART between January, 2007, and June, 2018, were retrospectively enrolled. Results: Of the 24 subjects, the mean age was 39.6 ± 10 years at the time of Graves disease diagnosis. The male to female ratio was 1:1.2. Palpitation and weight loss were the most common clinical manifestation

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Araújo, Denizar Vianna, Luciana Bahia, and Steffan Frosi Stella. "The Economic Burden of HIV/AIDS and Myocardial Infarction Treatment in Brazil." Scientific World Journal 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/864962.

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Objective. To analyze the expenses of HIV/AIDS and acute myocardial infarction (AMI) treatment in Brazil.Methods. A search in the Brazilian epidemiological database (DATASUS) on AMI and AIDS hospitalizations and their costs was done from January 1998 to December 2011. The number of HIV/AIDS cases and antiretroviral treatment (ART) costs was obtained from public Brazilian databases.Results. In 5 years, HIV/AIDS cases increased 38.5%, mainly in patients aged 25–49. There were 180,640 patients in ART in 2007 at a cost of R$ 3,920 per patient/year. The hospitalizations due to AIDS were stable over

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Gordon, E. O., L. A. Posokhova, A. S. Podymova, and E. B. Yastrebova. "JUSTIFICATION AND DEVELOPMENT OF ALGORITHM FOR PLANNED PARENTHOOD IN HIVSERODISCORDANT COUPLES." HIV Infection and Immunosuppressive Disorders 11, no. 1 (April 7, 2019): 38–45. http://dx.doi.org/10.22328/2077-9828-2019-11-1-38-45.

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Work objective: justification and development of algorithm for observation of HIV-serodiscordant couples at the stage of planning parenthood, including using Assisted Reproductive Technologies (ART) in Sverdlovsk region territory. Materials and methods. Statistical data were obtained from the materials of personal registration of people living with AIDS in State Budgetary Healthcare Institution of Sverdlovsk region «Sverdlovsk Regional Center on Prevention and Control of AIDS». 27 thousands of women of reproductive age and 31 thousands of men diagnosed with HIV infection were revealed in the r

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Loghin, Isabela Ioana, Șerban Alin Rusu, Andrei Vâţă, Mihaela Cobaschi, Ion Cecan, Carmen Manciuc, and Carmen Mihaela Dorobăţ. "Antiretroviral Therapy Switch in HIV-Infected Adults from a Regional HIV/AIDS Center in NE Romania." Medicina 60, no. 6 (May 24, 2024): 854. http://dx.doi.org/10.3390/medicina60060854.

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Background and Objectives: Antiretroviral therapy (ART) has revolutionized the management of HIV infection, transforming it from a once-debilitating disease to a chronic, manageable condition. However, challenges such as treatment resistance, medication side effects, and long-term tolerability persist, prompting the exploration of novel therapeutic approaches. We aimed to highlight the characteristics and related comorbidities of HIV/AIDS cases in which the antiretroviral therapy was modified. Material and Methods: A cross-sectional clinical investigation was conducted on adults diagnosed with

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Ayamah, Richard, Godwin Awuitor, and Zutaah Puotier. "MATHEMATICALLY MODELING THE SPREAD OF HIV/AIDS INFECTION AFTER THE INTRODUCTION OF ANTIRETROVIRAL THERAPY IN GHANA." American Journal of Computing and Engineering 3, no. 1 (November 2, 2020): 24–39. http://dx.doi.org/10.47672/ajce.602.

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One of the deadliest and highly infectious diseases is Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome (HIV-AIDS). One person was first diagnosed with HIV-AIDS in the Eastern region part of Ghana in 1986, followed by 41 more in the same year. The spread of the disease was so unbearable in the subsequent years (1987-2003), even after several intervention measures taken by Government and other stakeholders. Hence, in 2003, the antiretroviral therapy (ART) program was introduced by the Ghana AIDS Commission (GAC) through the Ghana Health Service (GHS) to sabotage the virus such t

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Olugbenga, Ijaodola Aremu. "Disease Severity, Health Beliefs, and Medication Adherence among HIV Patients in a Tertiary Hospital Abuja, Nigeria." TEXILA INTERNATIONAL JOURNAL OF PUBLIC HEALTH 9, no. 2 (June 30, 2021): 85–94. http://dx.doi.org/10.21522/tijph.2013.09.02.art008.

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Anti-Retroviral Therapy (ART) Has Decreased The Mortality And Morbidity Of HIV/AIDS. Several Medicines Are Prescribed For Disease Management; However, Adherence To Long-Term Therapy Remains Poor. Disease Severity And Health Beliefs About Medications Ultimately Influence Adherence To Treatment. There Is A Paucity Of Data With Regard To Disease Severity, Health Beliefs And Medication Adherence Among HIV Patients. The Purpose Of The Study Was To Investigate The Relationship Between Disease Severity, Health Beliefs, And Medication Adherence Among HIV Patients. A Cross-Sectional Descriptive Survey

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Tuychievna, Laziz N., Gulnara K. Khudaykulova, and Khumoyun Mirzo A. Sadikov. "INVESTIGATING FACTORS INFLUENCING ANTIRETROVIRAL THERAPY ADHERENCE TO ART IN HIV-INFECTED CHILDREN." Frontline Medical Sciences and Pharmaceutical Journal 02, no. 11 (November 1, 2022): 17–23. http://dx.doi.org/10.37547/medical-fmspj-02-11-03.

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This article examines the factors influencing adherence to antiretroviral therapy in ARVT among HIV-infected children. HIV infection is a chronic infectious disease with a progressive course, characterized by a specific lesion of the immune system with the development of immunodeficiency, which is manifested by secondary diseases. In this connection, people living with HIV (PLHIV) need medical care for the rest of their lives. Antiretroviral therapy (ART) is the only possible way to extend the life of people living with HIV (PLHIV), improve its quality and reduce the transmission of the virus

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Kumari, Rashmi, Mritunjay Kumar, and S. C. Mohapatra. "Clinico-demographic profile of HIV patients at ART centre of a tertiary care referral hospital in North India." International Journal Of Community Medicine And Public Health 4, no. 9 (August 23, 2017): 3166. http://dx.doi.org/10.18203/2394-6040.ijcmph20173632.

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Background: According to the National AIDS Control Organization (NACO), HIV prevalence in India is 0.36% and people living with HIV are around 2.47 million. Although antiretroviral treatment (ART) does not cure HIV/AIDS, but effective ART regimens inhibit the efficient replication of the HIV virus, and reduce viremia to undetectable levels. Methods: HIV positive patients qualified to be enrolled in to the study were those who attended the infectious diseases clinic at least twice (one follow-up visit at least six months apart), between January 2009 to December 2011. The protocol was approved b

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Isnard, Stéphane, Rayoun Ramendra, Franck P. Dupuy, John Lin, Brandon Fombuena, Nikola Kokinov, Ido Kema та ін. "Plasma Levels of C-Type Lectin REG3α and Gut Damage in People With Human Immunodeficiency Virus". Journal of Infectious Diseases 221, № 1 (23 серпня 2019): 110–21. http://dx.doi.org/10.1093/infdis/jiz423.

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Abstract Background Regenerating islet-derived protein 3α (REG3α) is an antimicrobial peptide secreted by intestinal Paneth cells. Circulating REG3α has been identified as a gut damage marker in inflammatory bowel diseases. People living with human immunodeficiency virus (PWH) on antiretroviral therapy (ART) present with an abnormal intestinal landscape leading to microbial translocation, persistent inflammation, and development of non-AIDS comorbidities. Herein, we assessed REG3α as a marker of gut damage in PWH. Methods Plasma from 169 adult PWH, including 30 elite controllers (ECs), and 30

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