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Letteratura scientifica selezionata sul tema "Apoptosis Immunological aspects"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 febbraio 2022

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Articoli di riviste sul tema "Apoptosis Immunological aspects"

Kokron, Cristina M., Paolo R. Errante, Myrthes T. Barros, Gisele V. Baracho, Maristela M. Camargo, Jorge Kalil, and Luiz V. Rizzo. "Clinical and laboratory aspects of common variable immunodeficiency." Anais da Academia Brasileira de Ciências 76, no. 4 (December 2004): 707–26. http://dx.doi.org/10.1590/s0001-37652004000400007.

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Common variable immunodeficiency (CVID) is an immunological disorder characterized by defective antibody production, recurrent infections, most notably of the respiratory tract, autoimmune phenomena and cancer. Some CVID patients may also present disturbances of the cellular immune response such as a decrease in the number and proportion of different lymphocyte populations, diminished lymphoproliferative response to mitogens and antigens, altered production of cytokines, and deficient expression of cell-surface molecules. Most Brazilian CVID patients included in this study show a decrease in T

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SALIKHOVA, T. R., N. S.-M. OMAROV, A. U. CHERKESOVA, S. M. GADJIMURADOVA, and E. R. ASKERKHANOVA. "CLINICO-MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL ASPECTS OF ENDOMETRIAL POLYP PATHOGENESIS IN POSTMENOPAUSE." Periódico Tchê Química 16, no. 32 (August 20, 2019): 724–31. http://dx.doi.org/10.52571/ptq.v16.n32.2019.742_periodico32_pgs_724_731.pdf.

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To study hypoxia-inducible transcription factor HIF-1α expression in endometrial polyps (EP) considering their clinical-morphological and immunological features during postmenopause. A complex clinical and laboratory examination of 120 postmenopausal patients was carried out. 90 of them developed EP, whereas 30 had morphologically unchanged endometrium. Immune histochemical (ICH) testing was used to evaluate HIF-1α expression in epithelial and stromal cells of polyps in adjacent and control endometrium. A complex of the most significant risk factors in EP genesis such as high rate of inflammat

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PASSOS, ELIANA M. DOS, VALÉRIA WANDERLEY-TEIXEIRA, EDMILSON J. MARQUES, ÁLVARO A. C. TEIXEIRA, and FÁBIO A. BRAYNER. "Cotesia flavipes (CAM) (Hymenoptera: Braconidae) Supresses Immune Responses In Diatraea flavipennella (BOX) (Lepidoptera: Crambidae)." Anais da Academia Brasileira de Ciências 86, no. 4 (December 2014): 2013–24. http://dx.doi.org/10.1590/0001-3765201420130393.

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The present research aimed to elucidate which aspects of immune responses in Diatraea flavipennella are suppressed by the parasitoid Cotesia flavipes, thus, ensuring parasitism success. We investigated the presence of apoptosis in fat body cells through the TUNEL technique. According to the results, reduced levels of nitric oxide and phenoloxidase activity were observed in larvae parasitized for three days, and reduced total number of hemocytes, after three and seven days. An increase in plasmatocytes and decrease in spherulocytes numbers were observed in the differential count on the third da

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Signorile, Anna, Anna Ferretta, Maddalena Ruggieri, Damiano Paolicelli, Paolo Lattanzio, Maria Trojano, and Domenico De Rasmo. "Mitochondria, Oxidative Stress, cAMP Signalling and Apoptosis: A Crossroads in Lymphocytes of Multiple Sclerosis, a Possible Role of Nutraceutics." Antioxidants 10, no. 1 (December 28, 2020): 21. http://dx.doi.org/10.3390/antiox10010021.

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Multiple sclerosis (MS) is a complex inflammatory and neurodegenerative chronic disease that involves the immune and central nervous systems (CNS). The pathogenesis involves the loss of blood–brain barrier integrity, resulting in the invasion of lymphocytes into the CNS with consequent tissue damage. The MS etiology is probably a combination of immunological, genetic, and environmental factors. It has been proposed that T lymphocytes have a main role in the onset and propagation of MS, leading to the inflammation of white matter and myelin sheath destruction. Cyclic AMP (cAMP), mitochondrial d

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Nicola, Monica-Georgiana, Liliana Mocanu, Aritina Elvira Morosanu, Sorin Berbece, and Loredana Elena Stoica. "The Immunohistochemical Expression of Bcl2, Ki 67and CD3 correlated with the Basal Cell Carcinoma Histological Features - a study on 10 cases." Revista de Chimie 71, no. 1 (February 7, 2020): 249–53. http://dx.doi.org/10.37358/rc.20.1.7841.

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The basal cell carcinoma represents a worldwide major health problem due to incidence, functional and aesthetical defects which accompanies the disease and its treatment and high recurrency risk.The various morphoclinical forms of the basal cell carcinoma may be explained due to at least three factors: genetical predisposal, the individual immunological status and the action of the risk factors. In the case in which the histological aspects do present some modifications which cannot be catalogued in the usual patterns, therefore inseriated sections of the hole tumor being imposed, in order to

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Yamamoto, Toshiyuki, and Ichiro Katayama. "Vascular Changes in Bleomycin-Induced Scleroderma." International Journal of Rheumatology 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/270938.

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Systemic sclerosis (SSc) is characterized by vascular injury, immunological abnormalities, and fibrosis of the skin as well as various internal organs. Vascular impairment is the early manifestation and plays a fundamental role in the pathogenesis of SSc. Recent studies suggest that complex interactions among the endothelial cells, pericytes, smooth muscle cells, and fibroblasts are involved in the systemic vasculopathy in SSc, and histological feature of proliferation of vascular wall is seen in the lesional scleroderma skin at the late stage of disease. One of the most representative mouse m

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Zivadinovic, Radomir, Aleksandra Petric, Goran Lilic, Vekoslav Lilic, and Biljana Djordjevic. "Persistent human papillomavirus infection in the etiology of cervical carcinoma: The role of immunological, genetic, viral and cellular factors." Srpski arhiv za celokupno lekarstvo 142, no. 5-6 (2014): 378–83. http://dx.doi.org/10.2298/sarh1406378z.

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The aim of this paper was to present the role of human papillomavirus (HPV) in cervical carcinogenesis from several aspects. By explaining the HPV virus lifecycle and structure, its effect on cervical cell cycle and subversion of immune response can be better understood. Early E region of the viral genome encodes proteins that are directly involved in carcinogenesis. The E6 protein binds to p53 protein (product of tumor-suppressor gene) blocking and degrading it, which in turn prevents cell cycle arrest and apoptosis induction. E6 is also capable of telomerase activation, which leads to cell i

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Brandler, Samantha, Alice Lepelley, Marion Desdouits, Florence Guivel-Benhassine, Pierre-Emmanuel Ceccaldi, Yves Lévy, Olivier Schwartz, and Arnaud Moris. "Preclinical Studies of a Modified Vaccinia Virus Ankara-Based HIV Candidate Vaccine: Antigen Presentation and Antiviral Effect." Journal of Virology 84, no. 10 (March 10, 2010): 5314–28. http://dx.doi.org/10.1128/jvi.02329-09.

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ABSTRACT Poxvirus-based human immunodeficiency virus (HIV) vaccine candidates are currently under evaluation in preclinical and clinical trials. Modified vaccinia virus Ankara (MVA) vectors have excellent safety and immunogenicity records, but their behavior in human cell cultures remains only partly characterized. We studied here various virological and immunological aspects of the interactions of MVA-HIV, a vaccine candidate developed by the French National Agency for AIDS Research (ANRS), with primary human cells. We report that MVA-HIV infects and drives Gag expression in primary macrophag

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Sochacka-Ćwikła, Aleksandra, Andrzej Regiec, Michał Zimecki, Jolanta Artym, Ewa Zaczyńska, Maja Kocięba, Iwona Kochanowska, Iwona Bryndal, Anna Pyra, and Marcin Mączyński. "Synthesis and Biological Activity of New 7-Amino-oxazolo[5,4-d]Pyrimidine Derivatives." Molecules 25, no. 15 (August 4, 2020): 3558. http://dx.doi.org/10.3390/molecules25153558.

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The synthesis of a series of novel 7-aminooxazolo[5,4-d]pyrimidines 5, transformations during their synthesis and their physicochemical characteristics have been described. Complete detailed spectral analysis of the intermediates 2–4, the N′-cyanooxazolylacetamidine by-products 7 and final compounds 5 has been carried out using MS, IR, 1D and 2D NMR spectroscopy. Theoretical research was carried out to explain the privileged formation of 7-aminooxazolo[5,4-d]pyrimidines in relation to the possibility of their isomer formation and the related thermodynamic aspects. Additionally, the single-crys

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Merani, Shaheed, and A. M. James Shapiro. "Current status of pancreatic islet transplantation." Clinical Science 110, no. 6 (May 15, 2006): 611–25. http://dx.doi.org/10.1042/cs20050342.

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DM (diabetes mellitus) is a metabolic disorder of either absolute or relative insulin deficiency. Optimized insulin injections remain the mainstay life-sustaining therapy for patients with T1DM (Type I DM) in 2006; however, a small subset of patients with T1DM (approx. 10%) are exquisitely sensitive to insulin and lack counter-regulatory measures, putting them at higher risk of neuroglycopenia. One alternative strategy to injected insulin therapy is pancreatic islet transplantation. Islet transplantation came of age when Paul E. Lacy successfully reversed chemical diabetes in rodent models in

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Più fonti

Tesi sul tema "Apoptosis Immunological aspects"

Dorstyn, Loretta Esterina. "The identification and characterisation of two novel Drosophila caspases, DRONC and DECAY." Title page, contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phd718.pdf.

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Abstract (sommario):

Includes a list of publications co-authored by the author during the preparation of this thesis. Thesis amendments in back leaf. Includes bibliographical references (leaves 123-168). The studies described concentrate on the cloning and characterisation of the two Drosophila caspases, DRONC and DECAY

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Cheung, Ka-wa Benny, and 張嘉華. "Mechanism of Bacillus Calmette Guerin-induced immune response." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29488989.

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Marshall, Aiden Christopher James 1976. "The role of Fas and TNFα in experimental autoimmune gastritis". Monash University, Dept. of Pathology and Immunology, 2003. http://arrow.monash.edu.au/hdl/1959.1/9413.

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Lacey, Derek. "NFκB independent pathway activation of rheumatoid arthritis FLS by macrophage migration inhibitory factor (MIF)". Monash University, Faculty of Medicine, 2003. http://arrow.monash.edu.au/hdl/1959.1/9457.

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Doumont, Gilles. "Identification et caractérisation de nouveaux médiateurs de l'activité biologique de la protéine suppresseur de tumeur p53." Doctoral thesis, Universite Libre de Bruxelles, 2005. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211022.

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Le suppresseur de tumeur p53 permet à la cellule de se défendre contre différentes formes de stress. Il joue un rôle de barrière s'opposant à la tumorigenèse: en effet la perte de p53 chez la souris prédispose grandement ces animaux à développer des tumeurs; de même le locus p53 est inactivé dans près de 50% des tumeurs humaines.<p>p53 constitue un facteur de transcription qui se lie à des séquences particulières de l'ADN et active l'expression des gènes adjacents. L'expression orchestrée de ces gènes conduit, directement ou indirectement et suivant le contexte cellulaire, soit à la mort de la

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Govender, Sumentheran Nadarajan. "The effects of high intensity exercise on lymphocyte DNA and antioxidant status in trained athletes." Thesis, 1998. http://hdl.handle.net/10413/7648.

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Apoptosis (programmed cell death) and exercise immunology have been the focus of research for the past five years. Trained athletes are particularly susceptible to a wide variety of viral and bacterial infections and this has been related to oxidative damage which is a mediator of apoptosis. Apoptosis, a normal physiological mechanism has also been implicated in the pathogenesis of a wide-variety of diseases. To date, the link between apoptosis and exercise has not been shown by established methods or ultrastructurally. The objective of the study was t.o determine the effects of a single bout

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Lewis, David. "Soypeptide lunasin in cytokine immunotherapy for lymphoma." Thesis, 2014. http://hdl.handle.net/1805/4845.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Immunostimulatory cytokines can enhance anti-tumor immunity and are part of the therapeutic armamentarium for cancer treatment. We previously reported that chemotherapy-treated lymphoma patients acquire a deficiency of Signal Transducer and Activator of Transcription 4 (STAT4), which results in defective IFNy production during clinical immunotherapy. With the goal of further improvement in cytokine-based immunotherapy, we examined the effects of a soybean peptide called lunasin that exhibits immunostimulatory effects on natural kille

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Wang, Ting. "Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction." Thesis, 2014. http://hdl.handle.net/1805/5584.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>With effective antiretroviral therapy (ART), cardiovascular diseases (CVD), are emerging as a major cause of morbidity and death in the aging population with HIV infection. Although this increase in CVD could be partially explained by the toxic effects of combined anti-retroviral therapy (ART), more recently, HIV infection has emerged as an independent risk factor for CVD. However, it is unclear how HIV can contribute to CVD in patients on ART, when viral titers are low or non-detectable. Here, we provide several lines of evidence th

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Sally, Benjamin Andrew. "Failure to process chromatin on apoptotic microparticles in the absence of deoxyribonuclease 1 like 3 drives the development of systemic lupus erythematosus." Thesis, 2017. https://doi.org/10.7916/D8XG9WSQ.

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Systemic lupus erythematosus is an autoinflammatory disorder driven by the development of autoantibodies to self-nucleic acids, in particular to DNA and to chromatin. Loss-of-function mutations of the secreted deoxyribonuclease DNASE1L3 have been implicated in the development of aggressive familial lupus. In addition, recent genome-wide association studies have linked a hypomorphic variant of DNASE1L3 to sporadic lupus. Studies in the lab determined that Dnase1l3-deficient mice develop rapid autoantibody responses against dsDNA and chromatin, and at older ages this leads to a lupus-like inflam

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Libri sul tema "Apoptosis Immunological aspects"

Advances in cancer research: Clusterin. London: Academic, 2009.

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(Editor), J. Tschopp, ed. Pathways for Cytolysis. Springer-Verlag, 1995.

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Capitoli di libri sul tema "Apoptosis Immunological aspects"

Parcells, Mark S., and Shane C. Burgess. "Immunological aspects of Marek’s disease virus (MDV)-induced lymphoma progression." In Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response, 169–91. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6729-7_11.

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