Accedi

Bibliografie tematiche / Apoptosis Immunological aspects / Articoli di riviste

Segui questo link per vedere altri tipi di pubblicazioni sul tema: Apoptosis Immunological aspects.

Articoli di riviste sul tema "Apoptosis Immunological aspects"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 febbraio 2022

Cita una fonte nei formati APA, MLA, Chicago, Harvard e in molti altri stili

Scegli il tipo di fonte:

Vedi i top-27 articoli di riviste per l'attività di ricerca sul tema "Apoptosis Immunological aspects".

Accanto a ogni fonte nell'elenco di riferimenti c'è un pulsante "Aggiungi alla bibliografia". Premilo e genereremo automaticamente la citazione bibliografica dell'opera scelta nello stile citazionale di cui hai bisogno: APA, MLA, Harvard, Chicago, Vancouver ecc.

Puoi anche scaricare il testo completo della pubblicazione scientifica nel formato .pdf e leggere online l'abstract (il sommario) dell'opera se è presente nei metadati.

Vedi gli articoli di riviste di molte aree scientifiche e compila una bibliografia corretta.

1

Kokron, Cristina M., Paolo R. Errante, Myrthes T. Barros, Gisele V. Baracho, Maristela M. Camargo, Jorge Kalil, and Luiz V. Rizzo. "Clinical and laboratory aspects of common variable immunodeficiency." Anais da Academia Brasileira de Ciências 76, no. 4 (December 2004): 707–26. http://dx.doi.org/10.1590/s0001-37652004000400007.

Testo completo

Abstract (sommario):

Common variable immunodeficiency (CVID) is an immunological disorder characterized by defective antibody production, recurrent infections, most notably of the respiratory tract, autoimmune phenomena and cancer. Some CVID patients may also present disturbances of the cellular immune response such as a decrease in the number and proportion of different lymphocyte populations, diminished lymphoproliferative response to mitogens and antigens, altered production of cytokines, and deficient expression of cell-surface molecules. Most Brazilian CVID patients included in this study show a decrease in T

Gli stili APA, Harvard, Vancouver, ISO e altri

2

SALIKHOVA, T. R., N. S.-M. OMAROV, A. U. CHERKESOVA, S. M. GADJIMURADOVA, and E. R. ASKERKHANOVA. "CLINICO-MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL ASPECTS OF ENDOMETRIAL POLYP PATHOGENESIS IN POSTMENOPAUSE." Periódico Tchê Química 16, no. 32 (August 20, 2019): 724–31. http://dx.doi.org/10.52571/ptq.v16.n32.2019.742_periodico32_pgs_724_731.pdf.

Testo completo

Abstract (sommario):

To study hypoxia-inducible transcription factor HIF-1α expression in endometrial polyps (EP) considering their clinical-morphological and immunological features during postmenopause. A complex clinical and laboratory examination of 120 postmenopausal patients was carried out. 90 of them developed EP, whereas 30 had morphologically unchanged endometrium. Immune histochemical (ICH) testing was used to evaluate HIF-1α expression in epithelial and stromal cells of polyps in adjacent and control endometrium. A complex of the most significant risk factors in EP genesis such as high rate of inflammat

Gli stili APA, Harvard, Vancouver, ISO e altri

3

PASSOS, ELIANA M. DOS, VALÉRIA WANDERLEY-TEIXEIRA, EDMILSON J. MARQUES, ÁLVARO A. C. TEIXEIRA, and FÁBIO A. BRAYNER. "Cotesia flavipes (CAM) (Hymenoptera: Braconidae) Supresses Immune Responses In Diatraea flavipennella (BOX) (Lepidoptera: Crambidae)." Anais da Academia Brasileira de Ciências 86, no. 4 (December 2014): 2013–24. http://dx.doi.org/10.1590/0001-3765201420130393.

Testo completo

Abstract (sommario):

The present research aimed to elucidate which aspects of immune responses in Diatraea flavipennella are suppressed by the parasitoid Cotesia flavipes, thus, ensuring parasitism success. We investigated the presence of apoptosis in fat body cells through the TUNEL technique. According to the results, reduced levels of nitric oxide and phenoloxidase activity were observed in larvae parasitized for three days, and reduced total number of hemocytes, after three and seven days. An increase in plasmatocytes and decrease in spherulocytes numbers were observed in the differential count on the third da

Gli stili APA, Harvard, Vancouver, ISO e altri

4

Signorile, Anna, Anna Ferretta, Maddalena Ruggieri, Damiano Paolicelli, Paolo Lattanzio, Maria Trojano, and Domenico De Rasmo. "Mitochondria, Oxidative Stress, cAMP Signalling and Apoptosis: A Crossroads in Lymphocytes of Multiple Sclerosis, a Possible Role of Nutraceutics." Antioxidants 10, no. 1 (December 28, 2020): 21. http://dx.doi.org/10.3390/antiox10010021.

Testo completo

Abstract (sommario):

Multiple sclerosis (MS) is a complex inflammatory and neurodegenerative chronic disease that involves the immune and central nervous systems (CNS). The pathogenesis involves the loss of blood–brain barrier integrity, resulting in the invasion of lymphocytes into the CNS with consequent tissue damage. The MS etiology is probably a combination of immunological, genetic, and environmental factors. It has been proposed that T lymphocytes have a main role in the onset and propagation of MS, leading to the inflammation of white matter and myelin sheath destruction. Cyclic AMP (cAMP), mitochondrial d

Gli stili APA, Harvard, Vancouver, ISO e altri

5

Nicola, Monica-Georgiana, Liliana Mocanu, Aritina Elvira Morosanu, Sorin Berbece, and Loredana Elena Stoica. "The Immunohistochemical Expression of Bcl2, Ki 67and CD3 correlated with the Basal Cell Carcinoma Histological Features - a study on 10 cases." Revista de Chimie 71, no. 1 (February 7, 2020): 249–53. http://dx.doi.org/10.37358/rc.20.1.7841.

Testo completo

Abstract (sommario):

The basal cell carcinoma represents a worldwide major health problem due to incidence, functional and aesthetical defects which accompanies the disease and its treatment and high recurrency risk.The various morphoclinical forms of the basal cell carcinoma may be explained due to at least three factors: genetical predisposal, the individual immunological status and the action of the risk factors. In the case in which the histological aspects do present some modifications which cannot be catalogued in the usual patterns, therefore inseriated sections of the hole tumor being imposed, in order to

Gli stili APA, Harvard, Vancouver, ISO e altri

6

Yamamoto, Toshiyuki, and Ichiro Katayama. "Vascular Changes in Bleomycin-Induced Scleroderma." International Journal of Rheumatology 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/270938.

Testo completo

Abstract (sommario):

Systemic sclerosis (SSc) is characterized by vascular injury, immunological abnormalities, and fibrosis of the skin as well as various internal organs. Vascular impairment is the early manifestation and plays a fundamental role in the pathogenesis of SSc. Recent studies suggest that complex interactions among the endothelial cells, pericytes, smooth muscle cells, and fibroblasts are involved in the systemic vasculopathy in SSc, and histological feature of proliferation of vascular wall is seen in the lesional scleroderma skin at the late stage of disease. One of the most representative mouse m

Gli stili APA, Harvard, Vancouver, ISO e altri

7

Zivadinovic, Radomir, Aleksandra Petric, Goran Lilic, Vekoslav Lilic, and Biljana Djordjevic. "Persistent human papillomavirus infection in the etiology of cervical carcinoma: The role of immunological, genetic, viral and cellular factors." Srpski arhiv za celokupno lekarstvo 142, no. 5-6 (2014): 378–83. http://dx.doi.org/10.2298/sarh1406378z.

Testo completo

Abstract (sommario):

The aim of this paper was to present the role of human papillomavirus (HPV) in cervical carcinogenesis from several aspects. By explaining the HPV virus lifecycle and structure, its effect on cervical cell cycle and subversion of immune response can be better understood. Early E region of the viral genome encodes proteins that are directly involved in carcinogenesis. The E6 protein binds to p53 protein (product of tumor-suppressor gene) blocking and degrading it, which in turn prevents cell cycle arrest and apoptosis induction. E6 is also capable of telomerase activation, which leads to cell i

Gli stili APA, Harvard, Vancouver, ISO e altri

8

Brandler, Samantha, Alice Lepelley, Marion Desdouits, Florence Guivel-Benhassine, Pierre-Emmanuel Ceccaldi, Yves Lévy, Olivier Schwartz, and Arnaud Moris. "Preclinical Studies of a Modified Vaccinia Virus Ankara-Based HIV Candidate Vaccine: Antigen Presentation and Antiviral Effect." Journal of Virology 84, no. 10 (March 10, 2010): 5314–28. http://dx.doi.org/10.1128/jvi.02329-09.

Testo completo

Abstract (sommario):

ABSTRACT Poxvirus-based human immunodeficiency virus (HIV) vaccine candidates are currently under evaluation in preclinical and clinical trials. Modified vaccinia virus Ankara (MVA) vectors have excellent safety and immunogenicity records, but their behavior in human cell cultures remains only partly characterized. We studied here various virological and immunological aspects of the interactions of MVA-HIV, a vaccine candidate developed by the French National Agency for AIDS Research (ANRS), with primary human cells. We report that MVA-HIV infects and drives Gag expression in primary macrophag

Gli stili APA, Harvard, Vancouver, ISO e altri

9

Sochacka-Ćwikła, Aleksandra, Andrzej Regiec, Michał Zimecki, Jolanta Artym, Ewa Zaczyńska, Maja Kocięba, Iwona Kochanowska, Iwona Bryndal, Anna Pyra, and Marcin Mączyński. "Synthesis and Biological Activity of New 7-Amino-oxazolo[5,4-d]Pyrimidine Derivatives." Molecules 25, no. 15 (August 4, 2020): 3558. http://dx.doi.org/10.3390/molecules25153558.

Testo completo

Abstract (sommario):

The synthesis of a series of novel 7-aminooxazolo[5,4-d]pyrimidines 5, transformations during their synthesis and their physicochemical characteristics have been described. Complete detailed spectral analysis of the intermediates 2–4, the N′-cyanooxazolylacetamidine by-products 7 and final compounds 5 has been carried out using MS, IR, 1D and 2D NMR spectroscopy. Theoretical research was carried out to explain the privileged formation of 7-aminooxazolo[5,4-d]pyrimidines in relation to the possibility of their isomer formation and the related thermodynamic aspects. Additionally, the single-crys

Gli stili APA, Harvard, Vancouver, ISO e altri

10

Merani, Shaheed, and A. M. James Shapiro. "Current status of pancreatic islet transplantation." Clinical Science 110, no. 6 (May 15, 2006): 611–25. http://dx.doi.org/10.1042/cs20050342.

Testo completo

Abstract (sommario):

DM (diabetes mellitus) is a metabolic disorder of either absolute or relative insulin deficiency. Optimized insulin injections remain the mainstay life-sustaining therapy for patients with T1DM (Type I DM) in 2006; however, a small subset of patients with T1DM (approx. 10%) are exquisitely sensitive to insulin and lack counter-regulatory measures, putting them at higher risk of neuroglycopenia. One alternative strategy to injected insulin therapy is pancreatic islet transplantation. Islet transplantation came of age when Paul E. Lacy successfully reversed chemical diabetes in rodent models in

Gli stili APA, Harvard, Vancouver, ISO e altri

11

Lawn, Stephen D., Salvatore T. Butera, and Thomas M. Folks. "Contribution of Immune Activation to the Pathogenesis and Transmission of Human Immunodeficiency Virus Type 1 Infection." Clinical Microbiology Reviews 14, no. 4 (October 1, 2001): 753–77. http://dx.doi.org/10.1128/cmr.14.4.753-777.2001.

Testo completo

Abstract (sommario):

SUMMARY The life cycle of human immunodeficiency virus type 1 (HIV-1) is intricately related to the activation state of the host cells supporting viral replication. Although cellular activation is essential to mount an effective host immune response to invading pathogens, paradoxically the marked systemic immune activation that accompanies HIV-1 infection in vivo may play an important role in sustaining phenomenal rates of HIV-1 replication in infected persons. Moreover, by inducing CD4+ cell loss by apoptosis, immune activation may further be central to the increased rate of CD4+ cell turnove

Gli stili APA, Harvard, Vancouver, ISO e altri

12

Li, Yanfei, and Ke Ren. "The Mechanism of Contrast-Induced Acute Kidney Injury and Its Association with Diabetes Mellitus." Contrast Media & Molecular Imaging 2020 (June 23, 2020): 1–10. http://dx.doi.org/10.1155/2020/3295176.

Testo completo

Abstract (sommario):

Contrast-induced acute kidney injury (CI-AKI) is the third most common hospital-acquired AKI after AKI induced by renal perfusion insufficiency and nephrotoxic drugs, taking great adverse effects on the prognosis and increasing hospital stay and medical cost. Diabetes nephropathy (DN) is a common chronic complication of DM (diabetes mellitus), and DN is an independent risk factor for chronic kidney disease (CKD) and CI-AKI. The incidence of CI-AKI significantly increases in patients with renal injury, especially in DM-related nephropathy. The etiology of CI-AKI is not fully clear, and research

Gli stili APA, Harvard, Vancouver, ISO e altri

13

Zhukova, O. B., N. V. Ryazantseva, and V. V. Novitsky. "Viral persistence: immunologic and molecular-genetic aspects of pathogenesis." Bulletin of Siberian Medicine 2, no. 4 (December 30, 2003): 113–20. http://dx.doi.org/10.20538/1682-0363-2003-4-113-120.

Testo completo

Abstract (sommario):

In the article a view of investigators on the modern understanding of long-term viral persistence forming mechanisms on cellular and molecular levels has been presented. A question on the role of persistent virus in the induction of changes in cellular differentiation character, of chromosome apparatus and of apoptosis of peripheral blood lymphocytes has been discussed.

Gli stili APA, Harvard, Vancouver, ISO e altri

14

Podoprigora, Gennadiy Ignat'evich, Lyudmila Ivanovna Kafarskaya, Nikolay Alekseevich Baynov, and Andrey Nikolaevich Shkoporov. "Bacterial Translocation from Intestine: Microbiological, Immunological and Pathophysiological Aspects." Annals of the Russian academy of medical sciences 70, no. 6 (December 6, 2015): 640–50. http://dx.doi.org/10.15690/vramn564.

Testo completo

Abstract (sommario):

Bacterial translocation (BT) is both pathology and physiology phenomenon. In healthy newborns it accompanies the process of establishing the autochthonous intestinal microbiota and the host microbiome. In immunodeficiency it can be an aethio-pathogenetic link and a manifestation of infection or septic complications. The host colonization resistance to exogenous microbic colonizers is provided by gastrointestinal microbiota in concert with complex constitutional and adaptive defense mechanisms. BT may be result of barrier dysfunction and self-purification mechanisms involving the host myeloid c

Gli stili APA, Harvard, Vancouver, ISO e altri

15

Troeger, Anja, Ludmila Glouchkova, Birgit Ackermann, Gabriele Escherich, Roland Meisel, Helmut Hanenberg, Gritta Janka, Ulrich Goebel, Hans-Juergen Laws, and Dagmar Dilloo. "High Expression of CD40 on BCP-ALL Blasts Is an Independent Risk Factor Associated with Improved Survival and Enhanced Capacity To Upregulate the Death Receptor CD95." Blood 108, no. 11 (November 1, 2006): 2282. http://dx.doi.org/10.1182/blood.v108.11.2282.2282.

Testo completo

Abstract (sommario):

Abstract Leukemogenesis is facilitated by deregulated survival signals and escape from immunosurveillance. For immunological control both adequate stimulation of effector cells as well as apoptosis sensitivity of target cells are required. The CD40 receptor, a member of the TNF/NGF receptor family, plays a pivotal role on normal B cells in both aspects as it upregulates the costimulatory molecules enhancing their antigen presenting capacity and the CD95 TNF receptor sensitizing cells to apoptotic stimuli. Due to its physiological immunomodulatory functions, we prospectively studied the prognos

Gli stili APA, Harvard, Vancouver, ISO e altri

16

Myint, A. M. "Role of Tryptophan-kynurenine Pathway in Depression: Psychopathological Aspect." European Psychiatry 24, S1 (January 2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70521-8.

Testo completo

Abstract (sommario):

It was reported that cytokines such as IFN-γ reduce the synthesis of 5-HT by stimulating the activity of indoleamine 2,3 dioxygenase (IDO) enzyme which degrades tryptophan to kynurenine. Kynurenine is further metabolized to kynurenic acid (KYNA), 3-hydroxykynurenine (3OHK) and quinolinic acid (QA) by kynurenine aminotransferase (KAT), kynurenine 3-monooxygenase (KMO) and kynureninase. Both KMO and kynureninase are also shown to be activated by IFNγ. The 3OHK is neurotoxic apoptotic while QA is the excitotoxic N-methyl-D-aspartate (NMDA) receptor agonist. Conversely KYNA is an antagonist of all

Gli stili APA, Harvard, Vancouver, ISO e altri

17

Zhelavskyi, M. M. "Changes in the immunobiological reactivity of the organism of cows in the pathogenesis of mastitis." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 83 (February 26, 2018): 77–82. http://dx.doi.org/10.15421/nvlvet8315.

Testo completo

Abstract (sommario):

Immunobiological aspects of the pathogenesis of mastitis of cows of the Ukrainian black-and-white breed are considered in the article. Based on the relevance of the topic, the aim of our work was to study the functional state of nonspecific immunobiological resistance and the specific immunobiological reactivity of the cows' organism during the development of mastitis. The features of the manifestation of immune reactions in the organism of animals in the development of subclinical and purulent-catarrhal mastitis have been studied. Clinical and experimental studies were conducted in Ukrainian

Gli stili APA, Harvard, Vancouver, ISO e altri

18

Zhelavskyi, M. M., and O. Ya Dmytriv. "Immunobiological status of the body of cows during mastitis." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 88 (August 25, 2018): 3–10. http://dx.doi.org/10.32718/nvlvet8801.

Testo completo

Abstract (sommario):

The work reveals the immunobiological aspects of lactation of cows and changes in immunobiological reactivity in the development of mastitis.The authors present modern scientific data on the local immune protection of the mammary gland of cows. Main stages of ontogenetic development of cellular immunity of the mammary gland of cows were traced during clinical and experimental studies. The number of somatic cells in the secret of the mammary gland of the primates was dependent on the period of the functioning of the mammary gland. In the cytology of colostrum mostly (56.00 ± 1.90%) neutrophil g

Gli stili APA, Harvard, Vancouver, ISO e altri

19

Zaitseva, N. V., M. A. Zemlianova, and Oleg V. Dolgikh. "GENOMIC, TRANSCRIPTOMIC AND PROTEOMIC TECHNOLOGIES AS A MODERN TOOL FOR HEALTH DISORDERS DIAGNOSTICS, ASSOCIATED WITH THE IMPACT OF ENVIRONMENTAL FACTORS." Hygiene and sanitation 99, no. 1 (January 15, 2020): 6–12. http://dx.doi.org/10.33029/0016-9900-2020-99-1-6-12.

Testo completo

Abstract (sommario):

Introduction. Today, it is relevant to use modern critical technologies for identifying and evaluating the negative effects associated with the effects of chemicals at the stages of pre-nosological changes. This improves the efficiency of the early detection of progress in pre-pathological conditions prior to the onset of pronounced functional changes and the aggravation of the disease. The use of molecular diagnostic methods based on genomic, transcriptomic, and proteomic analysis technologies is one of the most promising approaches. Aim of the work is an analysis of both aspects and practica

Gli stili APA, Harvard, Vancouver, ISO e altri

20

Mair, Johannes, Bertil Lindahl, Ola Hammarsten, Christian Müller, Evangelos Giannitsis, Kurt Huber, Martin Möckel, Mario Plebani, Kristian Thygesen, and Allan S. Jaffe. "How is cardiac troponin released from injured myocardium?" European Heart Journal: Acute Cardiovascular Care 7, no. 6 (December 27, 2017): 553–60. http://dx.doi.org/10.1177/2048872617748553.

Testo completo

Abstract (sommario):

Cardiac troponin I and cardiac troponin T are nowadays the criterion biomarkers for the laboratory diagnosis of acute myocardial infarction due to their very high sensitivities and specificities for myocardial injury. However, still many aspects of their degradation, tissue release and elimination from the human circulation are incompletely understood. Myocardial injury may be caused by a variety of different mechanisms, for example, myocardial ischaemia, inflammatory and immunological processes, trauma, drugs and toxins, and myocardial necrosis is preceded by a substantial reversible preletha

Gli stili APA, Harvard, Vancouver, ISO e altri

21

Johnson, Louise N. "The regulation of protein phosphorylation." Biochemical Society Transactions 37, no. 4 (July 22, 2009): 627–41. http://dx.doi.org/10.1042/bst0370627.

Testo completo

Abstract (sommario):

Phosphorylation plays essential roles in nearly every aspect of cell life. Protein kinases regulate signalling pathways and cellular processes that mediate metabolism, transcription, cell-cycle progression, differentiation, cytoskeleton arrangement and cell movement, apoptosis, intercellular communication, and neuronal and immunological functions. Protein kinases share a conserved catalytic domain, which catalyses the transfer of the γ-phosphate of ATP to a serine, threonine or tyrosine residue in protein substrates. The kinase can exist in an active or inactive state regulated by a variety of

Gli stili APA, Harvard, Vancouver, ISO e altri

22

Agius, Lawrence M. "Neuroinflammation as the Proximate Cause of Signature Pathogenic Pattern Progression in Amyotrophic Lateral Sclerosis, Aids, and Multiple Sclerosis." Pathology Research International 2012 (December 4, 2012): 1–5. http://dx.doi.org/10.1155/2012/169270.

Testo completo

Abstract (sommario):

The realization of injury to large motor neurons is embedded within contextual reference to the parallel pathways of apoptosis and necrosis of system-patterned evolution. A widespread loss of cell components occurs intracellularly and involves a reactive participation to a neuroinflammation that potentially is immunologically definable. In such terms, sporadic and hereditary forms of amyotrophic sclerosis are paralleled by the components of a reactive nature that involve the aggregation of proteins and conformational misfolding on the one hand and a powerful oxidative degradation that overwhel

Gli stili APA, Harvard, Vancouver, ISO e altri

23

Vojvodic, Jovana, Goran Mihajlovic, Ana Andonov, Milos Markovic, Jelena Djordjevic, and Petar Vojvodic. "Immunological Aspects of Depressive Disorder – The Review." Serbian Journal of Experimental and Clinical Research, February 1, 2019. http://dx.doi.org/10.2478/sjecr-2018-0076.

Testo completo

Abstract (sommario):

AbstractDepression represents a mood disorder and is considered to be one of the most common mental disorders in general. World Health Organization estimates that depression will be the leading cause of disability-adjusted life years, until 2030. Depression is a complex heterogeneous disorder where immune system and its regulation play an important role. Innate and adaptive immunity mecha nisms are included, along with processes of immune activation and suppression. The expression of humoral factors of innate immunity, especially pro-inflammatory cytokines, is increased, whereas the intensity

Gli stili APA, Harvard, Vancouver, ISO e altri

24

Barandalla Sobrados, M., P. Carullo, N. Salvarani, G. Condorelli, M. Miragoli, and D. Catalucci. "3072Myocardial delivery of therapeutic miR-133 via inhalable nanoparticles prevents the pathologic development in a model of ventricular pressure overload." European Heart Journal 40, Supplement_1 (October 1, 2019). http://dx.doi.org/10.1093/eurheartj/ehz745.0028.

Testo completo

Abstract (sommario):

Abstract Background MicroRNAs (miRs) are regulators involved in several biological processes and have been recognized as potential novel therapeutic targets for the treatment and prevention of CDs. We previously demonstrated that the cardiac-enriched miR-133, which is inversely related to failing heart conditions, is involved in several aspects of pathological cardiac remodeling via mitigation of cardiac hypertrophy and fibrosis, fine-tuning of the β1-adrenergic receptor signaling, and protection against oxidative stress-mediated apoptosis. However, effective and clinically oriented interventi

Gli stili APA, Harvard, Vancouver, ISO e altri

25

Chiu, Karen, Shah Tauseef Bashir, Romana A. Nowak, Wenyan Mei, and Jodi A. Flaws. "Subacute exposure to di-isononyl phthalate alters the morphology, endocrine function, and immune system in the colon of adult female mice." Scientific Reports 10, no. 1 (November 2, 2020). http://dx.doi.org/10.1038/s41598-020-75882-0.

Testo completo

Abstract (sommario):

Abstract Di-isononyl phthalate (DiNP), a common plasticizer used in polyvinyl chloride products, exhibits endocrine-disrupting capabilities. It is also toxic to the brain, reproductive system, liver, and kidney. However, little is known about how DiNP impacts the gastrointestinal tract (GIT). It is crucial to understand how DiNP exposure affects the GIT because humans are primarily exposed to DiNP through the GIT. Thus, this study tested the hypothesis that subacute exposure to DiNP dysregulates cellular, endocrine, and immunological aspects in the colon of adult female mice. To test this hypo

Gli stili APA, Harvard, Vancouver, ISO e altri

26

Beutgen, Vanessa M., Norbert Pfeiffer, and Franz H. Grus. "Serological Levels of Anti-clathrin Antibodies Are Decreased in Patients With Pseudoexfoliation Glaucoma." Frontiers in Immunology 12 (February 19, 2021). http://dx.doi.org/10.3389/fimmu.2021.616421.

Testo completo

Abstract (sommario):

Evidence for immunologic contribution to glaucoma pathophysiology is steadily increasing in ophthalmic research. Particularly, an altered abundance of circulating autoantibodies to ocular antigens is frequently observed. Here, we report an analysis of autoantibody abundancies to selected antigens in sera of open-angle glaucoma patients, subdivided into normal-tension glaucoma (N = 31), primary open-angle glaucoma (N = 43) and pseudoexfoliation glaucoma (N = 45), vs. a non-glaucomatous control group (N = 46). Serum samples were analyzed by protein microarray, including 38 antigens. Differences

Gli stili APA, Harvard, Vancouver, ISO e altri

27

Balasiddaiah, Anangi, Haleh Davanian, Soo Aleman, Anna Pasetto, Lars Frelin, Matti Sällberg, Volker Lohmann, Sarene Koh, Antonio Bertoletti, and Margaret Chen. "Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties." Journal of Virology 91, no. 9 (February 22, 2017). http://dx.doi.org/10.1128/jvi.00010-17.

Testo completo

Abstract (sommario):

ABSTRACT Therapy with genetically modified autologous T cells has shown great promise in cancer therapy. For an efficient control of hepatitis C virus (HCV) infection, cytotoxic T cells (CTL) are pivotal, but persistence of activated T cells may lead to liver toxicity. Here, anti-HCV T cell receptors (TCRs) recognizing the HCV nonstructural (NS) NS3 or NS5 viral peptide target were examined by mRNA transfection of human peripheral blood lymphocytes (PBLs) derived from healthy donors as well as chronically infected HCV patients. Immunological analysis shows that while the CTLs expressing the NS

Gli stili APA, Harvard, Vancouver, ISO e altri

Offriamo sconti su tutti i piani premium per gli autori le cui opere sono incluse in raccolte letterarie tematiche. Contattaci per ottenere un codice promozionale unico!