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1

Iwasaka, Chiharu, Tsubasa Mitsutake, and Etsuo Horikawa. "The Independent Relationship Between Leg Skeletal Muscle Mass Asymmetry and Gait Speed in Community-Dwelling Older Adults." Journal of Aging and Physical Activity 28, no. 6 (2020): 943–51. http://dx.doi.org/10.1123/japa.2019-0463.

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Objectives: To investigate the relationship between leg skeletal muscle mass asymmetry and usual gait speed in older adults. Methods: The subjects were 139 community-dwelling older adults. The asymmetry index was calculated using the leg skeletal muscle mass index (LSMI) values of both legs. The subjects were divided into “large” and “small” asymmetry groups based on the asymmetry index. The relationship between asymmetry and gait speed was analyzed using a linear regression model. The appendicular skeletal muscle mass index and LSMI were included as adjustment variables in the analysis. Resul
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2

Taniguchi, Yoshiaki, Hyuma Makizako, Ryoji Kiyama, et al. "The Association between Osteoporosis and Grip Strength and Skeletal Muscle Mass in Community-Dwelling Older Women." International Journal of Environmental Research and Public Health 16, no. 7 (2019): 1228. http://dx.doi.org/10.3390/ijerph16071228.

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This cross-sectional study investigated the association between osteoporosis, grip strength, and skeletal muscle mass in community-dwelling older women. Data obtained from 265 older women who participated in a community-based health check survey (Tarumizu Study) were analyzed. Face-to-face interviews with participants revealed their history of osteoporosis. Appendicular skeletal muscle mass was assessed through bioelectrical impedance analysis, and appendicular skeletal muscle index was calculated. Dominant grip strength was also assessed. Loss of skeletal muscle mass (appendicular skeletal mu
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3

Gallagher, Dympna, Marjolein Visser, Ronald E. De Meersman, et al. "Appendicular skeletal muscle mass: effects of age, gender, and ethnicity." Journal of Applied Physiology 83, no. 1 (1997): 229–39. http://dx.doi.org/10.1152/jappl.1997.83.1.229.

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Gallagher, Dympna, Marjolein Visser, Ronald E. De Meersman, Dennis Sepúlveda, Richard N. Baumgartner, Richard N. Pierson, Tamara Harris, and Steven B. Heymsfield. Appendicular skeletal muscle mass: effects of age, gender, and ethnicity. J. Appl. Physiol. 83(1): 229–239, 1997.—This study tested the hypothesis that skeletal muscle mass is reduced in elderly women and men after adjustment first for stature and body weight. The hypothesis was evaluated by estimating appendicular skeletal muscle mass with dual-energy X-ray absorptiometry in a healthy adult cohort. A second purpose was to test the h
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4

Osaka, Takafumi, Masahide Hamaguchi, and Michiaki Fukui. "Favorable Appendicular Skeletal Muscle Mass Changes in Older Patients With Type 2 Diabetes Receiving GLP-1 Receptor Agonist and Basal Insulin Co-Therapy." Clinical Medicine Insights: Endocrinology and Diabetes 16 (January 2023): 117955142311618. http://dx.doi.org/10.1177/11795514231161885.

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Background And Aims: Maintaining appendicular skeletal muscle mass is important for maintaining the quality of life of elderly patients with type 2 diabetes. The possibility of GLP-1 receptor agonists for maintaining appendicular skeletal muscle mass has previously been reported. We investigated changes in appendicular skeletal muscle mass, measured by body impedance analysis, in elderly patients who were hospitalized for diabetes self-management education. Methods: The study design was a retrospective longitudinal analysis of the changes in appendicular skeletal muscle mass in hospitalized pa
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5

Morris, Martha Savaria, and Paul F. Jacques. "Total protein, animal protein and physical activity in relation to muscle mass in middle-aged and older Americans." British Journal of Nutrition 109, no. 7 (2012): 1294–303. http://dx.doi.org/10.1017/s0007114512003133.

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Resistance training is recognised as a good strategy for retarding age-related declines in muscle mass and strength. Recent studies have also highlighted the potential value of protein intakes in excess of present recommendations. The roles that leisure-time physical activity and protein quality play in the preservation of skeletal muscle during ageing, and how such influences interact in free-living people are unclear. We sought to clarify these issues using data collected on 2425 participants aged ≥ 50 years in the US National Health and Nutrition Examination Survey (2003–2006). We estimated
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6

Moon, Hyun Eui, Tae Sic Lee, and Tae-Ha Chung. "Association between Lower-to-Upper Ratio of Appendicular Skeletal Muscle and Metabolic Syndrome." Journal of Clinical Medicine 11, no. 21 (2022): 6309. http://dx.doi.org/10.3390/jcm11216309.

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Abstract (sommario):
(1) Background: Metabolic syndrome (MetS) is a cluster-based disorder comprising several pre-disease or pre-clinical statuses for diabetes, hypertension, dyslipidemia, cardiovascular risk, and mortality. Appendicular skeletal muscle (ASM), or lean mass, is considered the main site of insulin-mediated glucose utilization. Therefore, we aimed to reveal the association between lower appendicular skeletal muscle mass to upper appendicular skeletal muscle mass ratio (LUR) and risk for MetS. (2) Methods: We analyzed the 2008–2011 Korean National Health Examination and Nutrition Survey (KNHANES) data
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7

Huang, Chienhsiu, and Min-Hong Hsieh. "Effects of Leucine Supplementation in Older Adults with Sarcopenia: A Meta-Analysis." Nutrients 17, no. 15 (2025): 2413. https://doi.org/10.3390/nu17152413.

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Background and Objectives: Research on the impact of leucine on older sarcopenic patients is scarce, and investigations on this subject have led to contradictory findings in the literature. Our goal was to compile data from the available studies in the literature to explore the effect of leucine supplementation on parameters associated with sarcopenia in elderly individuals. Methods: The meta-analysis included older persons over 65 years of age who were recruited on the basis of the European Working Group on Sarcopenia in Older People sarcopenia criteria. Studies that were included were those
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8

Stoika, I., R. Yatsyshyn, O. Drohomeretska, I. Popadynets, O. Babenko, and O. Shapoval. "Comparison of methods for diagnosing sarcopenia in patients with rheumatoid arthritis." PAIN, JOINTS, SPINE 14, no. 1 (2024): 15–20. http://dx.doi.org/10.22141/pjs.14.1.2024.408.

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Background. Sarcopenia in patients with rheumatoid arthritis (RA) occurs in connection with the chronic inflammatory process, hormonal therapy, and limitation of physical activity due to pain syndrome. For RA patients, it is important to preserve muscle mass and function to reduce the risk of disability and improve quality of life. The research purposed to assess muscle mass and function in RA patients with a comparison of me­thods for determining skeletal muscle mass recommended by ­EWCSOP2. ­Materials and methods. A total of 44 persons were exa­mined, 32 were patients with RA, and 12 ones we
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9

Park, Soyoung, Min-jeong Park, Eunjoo Kim, and Young-Woo Lim. "Gamitaeeumjowee-tang for Body Fat Loss in Female Patients with Sarcopenic Obesity: A Restrospective Chart Review." Journal of Korean Medicine 46, no. 2 (2025): 63–74. https://doi.org/10.13048/jkm.25018.

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Objectives: This study aims to evaluate the effects of Gamitaeeumjowee-tang on body weight and body composition in patients with sarcopenic obesity.Methods: A retrospective chart review was conducted on 51 adults with sarcopenic obesity who registered for a weight loss program with Gamitaeeumjowee-tang for 12 weeks. Body weight, body composition including body fat mass and appendicular skeletal muscle mass index was measured before and after the intervention.Results: A total of 51 patients were included in this study. After 12 weeks of treatment, the average weight loss rate was 6.52±3.4% (p&l
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10

Baek, Seol-Hee, Joo Hye Sung, Jin-Woo Park, Myeong Hun Son, Jung Hun Lee, and Byung-Jo Kim. "Usefulness of muscle ultrasound in appendicular skeletal muscle mass estimation for sarcopenia assessment." PLOS ONE 18, no. 1 (2023): e0280202. http://dx.doi.org/10.1371/journal.pone.0280202.

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The measurement of skeletal muscle mass is essential for the diagnosis of sarcopenia. Muscle ultrasonography has emerged as a useful tool for evaluating sarcopenia because it can be used to assess muscle quality and quantity. This study investigated whether muscle ultrasonography is effective for estimating appendicular skeletal muscle mass (ASM) and screening for sarcopenia. This study prospectively enrolled 212 healthy volunteers aged 40–80 years. ASM was measured using the bioelectrical impedance analysis. Muscle thickness (MT) and echo-intensity (EI) were measured in four muscles (biceps b
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11

Heymsfield, S. B., R. Smith, M. Aulet, et al. "Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry." American Journal of Clinical Nutrition 52, no. 2 (1990): 214–18. http://dx.doi.org/10.1093/ajcn/52.2.214.

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Raisbeck, Louisa D., Jonathon L. Stickford, Colleen M. McCracken, Sandra Tecklenberg, Jeanne D. Johnston, and Joel M. Stager. "Total Skeletal Muscle Mass, Appendicular Muscle Mass, Strength And Power In Master Athletes." Medicine & Science in Sports & Exercise 39, Supplement (2007): S220. http://dx.doi.org/10.1249/01.mss.0000273832.90257.70.

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13

Sui, Sophia X., Kara L. Holloway-Kew, Natalie K. Hyde, et al. "How Well Do Low Population-Specific Values for Muscle Parameters Associate with Indices of Poor Physical Health? Cross-Sectional Data from the Geelong Osteoporosis Study." Journal of Clinical Medicine 11, no. 10 (2022): 2906. http://dx.doi.org/10.3390/jcm11102906.

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We aimed to examine associations between skeletal muscle deficits and indices of poor health. Cut-points for skeletal muscle deficits were derived using data from the Geelong Osteoporosis Study and definitions from the revised European Consensus on Definition and Diagnosis and the Foundation for the National Institutes of Health. Participants (n = 665; 323 women) aged 60–96 year had handgrip strength measured by dynamometry and appendicular lean mass by whole-body dual-energy X-ray absorptiometry. Physical performance was assessed using the Timed Up and Go test. Sex-specific cut-points were eq
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14

Sarah Razaq, Murat Kara, Levent Özcakar, and Farooq Azam Rathore. "Diagnosis, management strategies and research horizons in sarcopenia." Journal of the Pakistan Medical Association 72, no. 5 (2022): 998–1001. http://dx.doi.org/10.47391/jpma.22-68.

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Abstract (sommario):
Sarcopenia was first described by Rosenberg as the agerelated loss of skeletal muscle mass. The early operational definitions of sarcopenia were based on low muscle mass alone. However, research has suggested a strong predictive relationship between measures of muscle quality i.e., strength and/or physical performance, and health outcomes. Therefore, the definition has been revised to "age-related loss of muscle mass and muscle function". The etiology of sarcopenia is multifactorial and diagnostic recommendations published to date have addressed the total or appendicular muscle mass. Measureme
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15

Nonaka, Koji, Shin Murata, Hideki Nakano, et al. "Association of Low Bone Mass with Decreased Skeletal Muscle Mass: A Cross-Sectional Study of Community-Dwelling Older Women." Healthcare 8, no. 3 (2020): 343. http://dx.doi.org/10.3390/healthcare8030343.

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This study aimed to investigate the characteristics of skeletal muscle mass, muscle strength, and physical performance among community-dwelling older women. Data were collected from 306 older adults, and the data of 214 older women were included in the final analysis. Participants’ calcaneus bone mass was measured using ultrasonography. Based on their T-scores, participants were divided into the following three groups: normal (T-score > −1), low (−2.5 < T-score ≤ −1), and very low (T-score ≤ −2.5) bone mass. Further, participants’ skeletal muscle mass, muscle strength (grip and knee exte
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16

Ohba, Tetsuro, Kotaro Oda, Nobuki Tanaka, Goto Go, and Hirotaka Haro. "Impact of Skeletal Muscle Mass on Physical Function and Locomotive Syndrome of Pre- and Postoperative Adult Spinal Deformity." Journal of Clinical Medicine 13, no. 3 (2024): 697. http://dx.doi.org/10.3390/jcm13030697.

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Background: The purpose of this study is to identify the relationship between locomotive syndrome (LS) status, physical performance and limb and trunk skeletal muscle mass before and after surgery in adult spinal surgery (ASD) patients. Methods: A retrospective observational investigation of 63 consecutive patients with ASD who underwent spinal surgery was conducted. The total skeletal muscle mass of the arms and legs was considered a measure of the total appendicular skeletal muscle mass measured with whole-body dual-energy X-ray absorptiometry. All data pertaining to the physical performance
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17

Duran, Ibrahim, Kyriakos Martakis, Mirko Rehberg, Christina Stark, Anne Koy, and Eckhard Schoenau. "The Appendicular Lean Mass Index Is a Suitable Surrogate for Muscle Mass in Children with Cerebral Palsy." Journal of Nutrition 149, no. 10 (2019): 1863–68. http://dx.doi.org/10.1093/jn/nxz127.

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ABSTRACT Background Densitometrically measured lean body mass (LBM) is often used to quantify skeletal muscle mass in children with cerebral palsy (CP). Since LBM depends on the individual's height, the evaluation of $\frac{{{\rm{LBM}}}}{{heigh{t^2}}}\ $ (lean BMI) is often recommended. However, LBM includes not only skeletal muscle mass but also the mass of skin, internal organs, tendons, and other components. This limitation applies to a far lesser extent to the appendicular lean mass index (LMIapp). Objectives The aim of the study was to evaluate skeletal muscle mass in children with CP usi
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18

Eriksen, Christian Skou, Nina Kimer, Charlotte Suetta, and Søren Møller. "Arm lean mass determined by dual-energy X-ray absorptiometry is superior to characterize skeletal muscle and predict sarcopenia-related mortality in cirrhosis." American Journal of Physiology-Gastrointestinal and Liver Physiology 320, no. 5 (2021): G729—G740. http://dx.doi.org/10.1152/ajpgi.00478.2020.

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Sarcopenia increases mortality in patients with end-stage liver disease. We show that arm lean mass determined by dual-energy X-ray absorptiometry is a better marker than the traditional appendicular skeletal muscle mass when predicting sarcopenia-related mortality in patients with cirrhosis of different severity. The findings add to the dispute about the optimal method for repeated assessments of skeletal muscle status in patients with cirrhosis and may have implications for clinical decision making.
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19

Kurose, Satoshi, Katsuko Onishi, Nana Takao, Takumi Miyauchi, Kazuhisa Takahashi, and Yutaka Kimura. "Association of serum adiponectin and myostatin levels with skeletal muscle in patients with obesity: A cross-sectional study." PLOS ONE 16, no. 1 (2021): e0245678. http://dx.doi.org/10.1371/journal.pone.0245678.

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Background Adiponectin has been reported to be associated with lower skeletal muscle mass and skeletal strength and may be involved in skeletal muscle regulation along with myostatin. This study aims to evaluate the association between serum adiponectin and myostatin levels and identify independent factors using body composition and metabolic parameters in patients with obesity. Methods Overall, 148 patients (age, 45.9 ± 14.3 years, body mass index, 37.2 ± 8.0 kg/m2) who initially visited the outpatient clinic of obesity between November 2013 and November 2019 were included. Body composition w
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20

Stookey, Jodi Dunmeyer. "Protein intake and appendicular skeletal muscle mass in older men." American Journal of Clinical Nutrition 71, no. 5 (2000): 1209. http://dx.doi.org/10.1093/ajcn/71.5.1209.

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21

Moon, Ji Hyun, Yun Hwan Oh, Mi Hee Kong, and Hyeon Ju Kim. "Relationship between visual acuity and muscle mass in the Korean older population: a cross-sectional study using Korean National Health and Nutrition Examination Survey." BMJ Open 9, no. 12 (2019): e033846. http://dx.doi.org/10.1136/bmjopen-2019-033846.

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ObjectivesWe aimed to assess the effects of visual acuity on muscle mass, which is an important indicator of health in older populations.DesignPooled-sample cross-sectional study.SettingNationally representative population survey data.ParticipantsThe present study analysed men aged 65 years or older who participated in the Korea National Health and Nutrition Examination Survey (KNHANES, 2008–2011).Primary and secondary outcome measuresMuscle mass was measured by dual-energy X-ray absorptiometry scan, and low muscle mass was defined as appendicular skeletal mass divided by height squared (kg/m2
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Zhang, Yajie, Dajiang Lu, Renwei Wang, Weijie Fu, and Shengnian Zhang. "Relationship between Muscle Mass/Strength and Hepatic Fat Content in Post-Menopausal Women." Medicina 55, no. 10 (2019): 629. http://dx.doi.org/10.3390/medicina55100629.

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Background and Objectives: Recent studies have shown that low skeletal muscle mass can contribute to non-alcoholic fatty liver disease through insulin resistance. However, the association between muscle mass/strength and hepatic fat content remains unclear in postmenopausal women. Methods: In this study, we assessed the associations between muscle mass/strength and various severities of non-alcoholic fatty liver disease. Using single-voxel proton magnetic resonance spectroscopy, 96 postmenopausal women between the ages of 50 and 65 were divided into four groups (G0–G3) by hepatic fat content:
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23

Juppi, Hanna-Kaarina, Sarianna Sipilä, Neil J. Cronin, et al. "Role of Menopausal Transition and Physical Activity in Loss of Lean and Muscle Mass: A Follow-Up Study in Middle-Aged Finnish Women." Journal of Clinical Medicine 9, no. 5 (2020): 1588. http://dx.doi.org/10.3390/jcm9051588.

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In midlife, women experience hormonal changes due to menopausal transition. A decrease especially in estradiol has been hypothesized to cause loss of muscle mass. This study investigated the effect of menopausal transition on changes in lean and muscle mass, from the total body to the muscle fiber level, among 47–55-year-old women. Data were used from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, where 234 women were followed from perimenopause to early postmenopause. Hormone levels (estradiol and follicle stimulating hormone), total and regional body composition (dual-energy X-r
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24

Riviati, Nur, Ari Dwi Prasetyo, Rizki Bastari, Surya Darma, and Erial Bahar. "Accuracy of Fat Mass and Muscle Mass Measured by Bioelectrical Impedance Analysis in Predicting Osteoporosis in Older Adults." Bioscientia Medicina : Journal of Biomedicine and Translational Research 9, no. 2 (2024): 6277–88. http://dx.doi.org/10.37275/bsm.v9i2.1191.

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Background: Osteoporosis is a prevalent bone disease characterized by reduced bone mineral density (BMD) and increased fracture risk. This study aimed to evaluate the accuracy of fat mass (FM) and muscle mass measured by bioelectrical impedance analysis (BIA) in predicting osteoporosis in older adults. Methods: A cross-sectional study was conducted on 109 outpatients aged 60 years and older. FM parameters (total fat mass, visceral fat level, and fat mass index [FMI]) and muscle mass parameters (total muscle mass, appendicular skeletal muscle mass [ASM], and appendicular skeletal muscle mass in
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Schweighofer, Natascha, Christoph W. Haudum, Olivia Trummer, et al. "Dp-ucMGP as a Biomarker in Sarcopenia." Nutrients 14, no. 24 (2022): 5400. http://dx.doi.org/10.3390/nu14245400.

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Sarcopenia is linked with an increased risk of falls, osteoporosis and mortality and is an increasing problem for healthcare systems. No satisfying biomarkers for sarcopenia diagnosis exist, connecting bone, fat and muscle. Matrix-GLA-protein (MGP) is an adipokine that regulates bone metabolism and is associated with decreased muscle strength. Associations of dp-ucMGP were analyzed in the BioPersMed cohort (58 ± 9 years), including 1022 asymptomatic subjects at moderate cardiovascular risk. Serum measurements of dp-ucMGP in 760 persons were performed with the InaKtif MGP Kit with the IDS-iSYS
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Asare, Nana K., Steven B. Heymsfield, Mary N. Horlick, Alfredo Jones II, Mark Punyanita, and Steven C. Doleckyj. "DXA Appendicular Lean Soft Tissue Association with Skeletal Muscle Mass Function." Medicine & Science in Sports & Exercise 36, Supplement (2004): S70. http://dx.doi.org/10.1249/00005768-200405001-00330.

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Asare, Nana K., Steven B. Heymsfield, Mary N. Horlick, Alfredo Jones II, Mark Punyanita, and Steven C. Doleckyj. "DXA Appendicular Lean Soft Tissue Association with Skeletal Muscle Mass Function." Medicine & Science in Sports & Exercise 36, Supplement (2004): S70. http://dx.doi.org/10.1097/00005768-200405001-00330.

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Pietrobelli, A., P. Morini, N. Battistini, G. Chiumello, C. Nuñez, and SB Heymsfield. "Appendicular skeletal muscle mass: prediction from multiple frequency segmental bioimpedance analysis." European Journal of Clinical Nutrition 52, no. 7 (1998): 507–11. http://dx.doi.org/10.1038/sj.ejcn.1600592.

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Teixeira, Leonardo Augusto Costa, Jousielle Marcia dos Santos, Adriana Netto Parentoni, et al. "Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study." Journal of Clinical Medicine 11, no. 23 (2022): 7175. http://dx.doi.org/10.3390/jcm11237175.

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Abstract (sommario):
Inflammation is a chronic, sterile, low-grade inflammation that develops with advanced age in the absence of overt infection and may contribute to the pathophysiology of sarcopenia, a progressive and generalized skeletal muscle disorder. Furthermore, a series of biomarkers linked to sarcopenia occurrence have emerged. To aid diagnostic and treatment strategies for low muscle mass in sarcopenia and other related conditions, the objective of this work was to investigate potential biomarkers associated with appendicular lean mass in community-dwelling older women. This is a cross-sectional study
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Lee, Jun-Hyuk, Hye-Sun Lee, Byoung-Kwon Lee, Yu-Jin Kwon, and Ji-Won Lee. "Relationship between Muscle Mass and Non-Alcoholic Fatty Liver Disease." Biology 10, no. 2 (2021): 122. http://dx.doi.org/10.3390/biology10020122.

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Although sarcopenia is known to be a risk factor for non-alcoholic fatty liver disease (NAFLD), whether NAFLD is a risk factor for the development of sarcopenia is not clear. We investigated relationships between NAFLD and low skeletal muscle mass index (LSMI) using three different datasets. Participants were classified into LSMI and normal groups. LSMI was defined as a body mass index (BMI)-adjusted appendicular skeletal muscle mass <0.789 in men and <0.512 in women or as the sex-specific lowest quintile of BMI-adjusted total skeletal muscle mass. NAFLD was determined according to NAFLD
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Rios-Escalante, Violeta, Juan Carlos Perez-Barba, Maria Claudia Espinel-Bermudez, et al. "Effects of a Multicomponent Preventive Intervention in Women at Risk of Sarcopenia: A Pilot Study." Healthcare 12, no. 12 (2024): 1191. http://dx.doi.org/10.3390/healthcare12121191.

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Sarcopenia is defined by the presence of decreased skeletal muscle mass, strength, and functionality in older people. Multicomponent interventions represent an alternative to non-pharmacological treatment for preventing disease progression. This study aimed to evaluate the effects of a multicomponent intervention approach in women at risk of sarcopenia. Methods: A quasi-experimental pilot study of 12 weeks was conducted, with 24 sessions of dancing and resistance exercises and 12 sessions of nutritional education. The outcomes were changes in muscle mass, grip strength, gait speed, and body co
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Mamutova, E. M., A. F. Sheptulina, Yu S. Timofeev, A. A. Yafarova, V. A. Metelskaya, and O. M. Drapkina. "Serum concentrations of irisin, erythroferrone, myostatin and interleukin-6 in obese patients depending on the presence of sarcopenia." Russian Journal of Preventive Medicine 28, no. 2 (2025): 67. https://doi.org/10.17116/profmed20252802167.

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Objective. To characterize and compare myokine profiles in patients with obesity depending on the presence of sarcopenia. Materials and Methods. The study included 77 patients with obesity examined at the National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Health of Russia from January 2023 to April 2024. Sarcopenia was diagnosed using criteria including handgrip strength, skeletal muscle mass, and physical function assessment. Serum erythroferrone, irisin, myostatin, and interleukin (IL)-6 were assessed using enzyme-linked immunosorbent assay. Results. Thir
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Song, Mi-Yeon, Jaehee Kim, Mary Horlick, et al. "Prepubertal Asians have less limb skeletal muscle." Journal of Applied Physiology 92, no. 6 (2002): 2285–91. http://dx.doi.org/10.1152/japplphysiol.01066.2001.

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Skeletal muscle mass in prepubertal Asian children has not been examined previously. The aims of this study were to test the hypotheses that 1) prepubertal Asians have less appendicular skeletal muscle (ASM) mass compared with African-Americans and Caucasians, and 2) ASM is less in prepubertal Asian girls compared with Asian boys. ASM was estimated by using dual-energy X-ray absorptiometry in healthy prepubertal girls ( n = 170) and boys ( n= 166). The results showed that, after adjusting for age, height, and body weight, 1) Asian girls and boys had less amounts of ASM than African-Americans (
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Liu, Qiaoling, Luonan Wang, Yuge Ma, and Yunjie Geng. "Association between dietary knowledge and muscle mass in Chinese older adults: a cross-sectional and longitudinal study." BMJ Open 13, no. 12 (2023): e075964. http://dx.doi.org/10.1136/bmjopen-2023-075964.

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ObjectivesThis study aims to explore the possible association between dietary knowledge and muscle mass in a Chinese population aged 60 years and above.DesignCross-sectional and longitudinal studies.SettingData from the 2006 and 2011 China Health and Nutrition Survey (CHNS) were used for this study.ParticipantsA total of 1487 Chinese participants (44.38% males) aged 60 and above in the 2006 survey were included in the cross-sectional study. From the same study population, a total of 1023 participants (46.82% males) with normal muscle mass on the interview date of 2006 were included in the long
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Ştefănescu, Camelia-Florina. "Nutrition and Physical Activity in the Elderly." Kompass Nutrition & Dietetics 3, no. 2 (2023): 66–68. http://dx.doi.org/10.1159/000533176.

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<b>Purpose:</b> Spinal sarcopenia is a multifactorial disorder associated with atrophy and fatty changes in paraspinal muscles. Interventional studies for spinal sarcopenia are limited. We aimed to evaluate the effectiveness of a combined exercise and nutrition intervention for the treatment of spinal sarcopenia. <b>Methods:</b> 35 community-dwelling older women diagnosed with spinal sarcopenia in a previous cohort study were included. The 12-week combined intervention consisted of back extensor strengthening exercises and protein supplementation. The following outcomes
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Proctor, David N., and Michael J. Joyner. "Skeletal muscle mass and the reduction ofV˙o 2 max in trained older subjects." Journal of Applied Physiology 82, no. 5 (1997): 1411–15. http://dx.doi.org/10.1152/jappl.1997.82.5.1411.

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Proctor, David N., and Michael J. Joyner. Skeletal muscle mass and the reduction ofV˙o 2 max in trained older subjects. J. Appl. Physiol.82(5): 1411–1415, 1997.—The role of skeletal muscle mass in the age-associated decline in maximal O2 uptake (V˙o 2 max) is poorly defined because of confounding changes in muscle oxidative capacity and in body fat and the difficulty of quantifying active muscle mass during exercise. We attempted to clarify these issues by examining the relationship between several indexes of muscle mass, as estimated by using dual-energy X-ray absorptiometry and treadmillV˙o
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Massimino, Elena, Anna Izzo, Gabriele Riccardi, and Giuseppe Della Pepa. "The Impact of Glucose-Lowering Drugs on Sarcopenia in Type 2 Diabetes: Current Evidence and Underlying Mechanisms." Cells 10, no. 8 (2021): 1958. http://dx.doi.org/10.3390/cells10081958.

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Abstract (sommario):
The age-related decrease in skeletal muscle mass together with the loss of muscle power and function is defined sarcopenia. Mounting evidence suggests that the prevalence of sarcopenia is higher in patients with type 2 diabetes mellitus (T2DM), and different mechanisms may be responsible for this association such as impaired insulin sensitivity, chronic hyperglycemia, advanced glycosylation end products, subclinical inflammation, microvascular and macrovascular complications. Glucose-lowering drugs prescribed for patients with T2DM might impact on these mechanisms leading to harmful or benefic
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Sugimura, Yoshikuni, Akira Kanda, Kaori Sawada, et al. "Association between Gut Microbiota and Body Composition in Japanese General Population: A Focus on Gut Microbiota and Skeletal Muscle." International Journal of Environmental Research and Public Health 19, no. 12 (2022): 7464. http://dx.doi.org/10.3390/ijerph19127464.

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This study aimed to investigate the gut microbial genera associated with skeletal muscle mass, using a large-scale survey from the standpoint of preventing sarcopenia. A total of 848 participants were included in the analysis. The mean (SD) ages of men (n = 353) and women (n = 495) were 50.0 (12.9) years and 50.8 (12.8) years, respectively. Body composition was assessed using appendicular skeletal muscle mass/body weight (ASM/BW), ASM, and BW. Additionally, the relationship between gut microbial genera and body composition was analyzed. The means (SD) of ASM/BW were 34.9 (2.4) % in men and 29.
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Gallagher, Dympna, Else Ruts, Marjolein Visser, et al. "Weight stability masks sarcopenia in elderly men and women." American Journal of Physiology-Endocrinology and Metabolism 279, no. 2 (2000): E366—E375. http://dx.doi.org/10.1152/ajpendo.2000.279.2.e366.

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Skeletal muscle loss or sarcopenia in aging has been suggested in cross-sectional studies but has not been shown in elderly subjects using appropriate measurement techniques combined with a longitudinal study design. Longitudinal skeletal muscle mass changes after age 60 yr were investigated in independently living, healthy men ( n = 24) and women ( n = 54; mean age 73 yr) with a mean ± SD follow-up time of 4.7 ± 2.3 yr. Measurements included regional skeletal muscle mass, four additional lean components (fat-free body mass, body cell mass, total body water, and bone mineral), and total body f
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Nielsen, Rikke Lundsgaard, Aino Leegaard Andersen, Thomas Kallemose, et al. "Evaluation of Multi-Frequency Bioelectrical Impedance Analysis against Dual-Energy X-ray Absorptiometry for Estimation of Low Muscle Mass in Older Hospitalized Patients." Journal of Clinical Medicine 13, no. 1 (2023): 196. http://dx.doi.org/10.3390/jcm13010196.

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The accuracy of multi-frequency (MF) bioelectrical impedance analysis (BIA) to estimate low muscle mass in older hospitalized patients remains unclear. This study aimed to describe the ability of MF-BIA to identify low muscle mass as proposed by The Global Leadership Initiative on Malnutrition (GLIM) and The European Working Group on Sarcopenia in Older People (EWGSOP-2) and examine the association between muscle mass, dehydration, malnutrition, and poor appetite in older hospitalized patients. In this prospective exploratory cohort study, low muscle mass was estimated with MF-BIA against dual
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Detopoulou, Paraskevi, Olga Magni, Ioanna Pylarinou, et al. "Appendicular Skeletal Muscle Index Is Positively Related to Mediterranean Diet Adherence in University Students." Diseases 13, no. 1 (2024): 3. https://doi.org/10.3390/diseases13010003.

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Abstract (sommario):
Skeletal muscle is associated with cardiometabolic health. The appendicular skeletal muscle index (aSMI) represents the skeletal muscle mass “corrected” for height and constitutes a clinically applicable feature of sarcopenia. The relation of the aSMI with dietary habits is not clear, especially in young adults. The present pilot study aimed to investigate the relationship between the aSMI and Mediterranean diet adherence in young adults. A cross-sectional study of 151 university students was conducted. Anthropometry and bioimpedance analysis (TANITA-MC780) were performed. The aSMI was calcula
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Starling, R. D., P. A. Ades, and E. T. Poehlman. "PHYSICAL ACTIVITY, PROTEIN INTAKE, AND APPENDICULAR SKELETAL MUSCLE MASS IN OLDER MEN." Medicine & Science in Sports & Exercise 31, Supplement (1999): S163. http://dx.doi.org/10.1097/00005768-199905001-00706.

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Starling, Raymond D., Philip A. Ades, and Eric T. Poehlman. "Physical activity, protein intake, and appendicular skeletal muscle mass in older men." American Journal of Clinical Nutrition 70, no. 1 (1999): 91–96. http://dx.doi.org/10.1093/ajcn/70.1.91.

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44

Romejko, Katarzyna, Katarzyna Szamotulska, Aleksandra Rymarz, and Stanisław Niemczyk. "Muscle Mass and Muscle Strength in Non-Dialysis-Dependent Chronic Kidney Disease Patients." Journal of Clinical Medicine 13, no. 21 (2024): 6448. http://dx.doi.org/10.3390/jcm13216448.

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Abstract (sommario):
Background: Sarcopenia is a state with a progressive and generalized loss of skeletal muscle mass and strength. However, muscle strength and muscle mass are different features, which are usually not studied separately. The aim of the study was to investigate anthropometric and clinical correlates and sources of variation in both skeletal muscle mass and muscle strength in chronic kidney disease (CKD). Methods: The study sample consisted of 84 patients with an estimated glomerular filtration rate (eGFR) < 45 mL/min/1.73 m2. Muscle strength was estimated by measuring hand grip strength (HGS).
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Cebrià i Iranzo, Maria À., Mercè Balasch-Bernat, María Á. Tortosa-Chuliá, and Sebastià Balasch-Parisi. "Effects of Resistance Training of Peripheral Muscles Versus Respiratory Muscles in Older Adults With Sarcopenia Who are Institutionalized: A Randomized Controlled Trial." Journal of Aging and Physical Activity 26, no. 4 (2018): 637–46. http://dx.doi.org/10.1123/japa.2017-0268.

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This study compares the effects of two resistance training programs in peripheral and respiratory musculature on muscle mass and strength and physical performance and identifies the appropriate muscle mass parameter for assessing the intervention effects. Thirty-seven institutionalized older Spanish adults with sarcopenia were analyzed: control group (n = 17), respiratory muscle training group (n = 9), and peripheral muscle training group (n = 11). Measured outcomes were appendicular skeletal muscle mass (ASM/height2, ASM/weight, and ASM/BMI), isometric knee extension, arm flexion and handgrip
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Zheng, Biao, Yuxin Zheng, Yongze Zhang, et al. "Precedence of Bone Loss Accompanied with Changes in Body Composition and Body Fat Distribution in Patients with Type 2 Diabetes Mellitus." Journal of Diabetes Research 2023 (April 17, 2023): 1–11. http://dx.doi.org/10.1155/2023/6753403.

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Abstract (sommario):
Background and Objective. Diabetes and osteoporosis are common diseases in elderly people, which are often accompanied by changes in body weight during treatment. No unified conclusion has been reached on the correlation between body weight and osteoporosis yet. This study is aimed at analyzing the correlation between body composition and bone mineral density (BMD) in patients with type 2 diabetes mellitus (T2DM). Methods. A total of 596 patients with T2DM, including 308 male and 288 female patients, were included in the follow-up study; the median follow-up time was 2.17 years. We calculated
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Chen, Guan-Bo, Che-Wei Lin, Hung-Ya Huang, et al. "Using Virtual Reality–Based Rehabilitation in Sarcopenic Older Adults in Rural Health Care Facilities—A Quasi-Experimental Study." Journal of Aging and Physical Activity 29, no. 5 (2021): 866–77. http://dx.doi.org/10.1123/japa.2020-0222.

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Abstract (sommario):
Because of a shortage of health care providers, providing rehabilitation in health care facilities is difficult. Virtual reality–based rehabilitation is effective in older populations. There are only a few studies among patients with sarcopenia. This is a quasi-experimental, single-group, pretest–posttest design evaluating the clinical effectiveness of virtual reality–based progressive resistance training among residents aged over 60 years with sarcopenia in rural care facilities. The authors used Oculus Rift with headsets to provide the virtual reality–based progressive resistance training. T
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48

Buscemi, Carola, Yvelise Ferro, Roberta Pujia, et al. "Sarcopenia and Appendicular Muscle Mass as Predictors of Impaired Fasting Glucose/Type 2 Diabetes in Elderly Women." Nutrients 13, no. 6 (2021): 1909. http://dx.doi.org/10.3390/nu13061909.

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Abstract (sommario):
Elderly women exhibit a high risk of type 2 diabetes (T2D), but no definitive data exist about the possible role of postmenopausal increases in visceral adiposity, the loss of lean body mass, or decreases in the sum of the lean mass of arms and legs (appendicular skeletal muscle mass (ASMM)). This retrospective, longitudinal study investigated whether body composition (bioelectrical impedance analysis) predicted the development of impaired fasting glucose (IFG) or T2D in a cohort of 159 elderly women (age: 71 ± 5 years, follow-up: 94 months) from southern Italy (Clinical Nutrition and Geriatri
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49

Levine, James A., Lana Abboud, Mitchel Barry, Judd E. Reed, Patrick F. Sheedy, and Michael D. Jensen. "Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry." Journal of Applied Physiology 88, no. 2 (2000): 452–56. http://dx.doi.org/10.1152/jappl.2000.88.2.452.

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Abstract (sommario):
Dual-energy X-ray absorptiometry (DEXA) is reported to be inferior to computed tomography (CT) to measure changes in appendicular soft tissue composition. We compared CT- and DEXA-measured thigh muscle and fat mass to evaluate the random and systematic discrepancies between these two methods. Thigh skeletal muscle area (single-slice CT) was suboptimally ( r 2= 0.74, P < 0.0001) related to DEXA-measured thigh fat-free mass (FFM). In contrast, thigh muscle and adipose tissue volumes (multislice CT) were highly related to DEXA-measured thigh FFM and fat (both r 2 = 0.96, P < 0.0001). DEXA-m
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50

CHANG, E. J., H. W. JUNG, S. W. KIM, et al. "DETERMINING THE CUT-OFF VALUES FOR SARCOPENIA IN THE KOREAN ELDERLY POPULATION USING BIOIMPEDANCE ANALYSIS." Journal of Frailty & Aging, 2015, 1–7. http://dx.doi.org/10.14283/jfa.2015.38.

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Abstract (sommario):
Background: Bioimpedance analysis (BIA) is known to be a useful method for assessing sarcopenia because cost-effective and not involving radiation exposure. However, the cut-off values for sarcopenia using BIA have not yet been determined in the Korean population. Objectives: To establish the cut-off values for sarcopenia in the Korean elderly population with the use of BIA. Methods: Body composition assessed by BIA was obtained in 7,641 participants aged 20–34 years and 3,902 participants aged ≥65 years from data routinely collected during health examinations at Seoul National University Gang
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