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1

Hubbs, Clark. "Biological Invasions in Europe and the Mediterranean Basin. Monographie Biologicae, Volume 65. F. di Castri , A. J. Hansen , M. DebusscheDynamics of Biological Invasions. Rob HengeveldEingeburgerte Fischarten: Zur Biologie und Verbreitung Allochthoner Wildfische in Europa. Die Neue Brehm-Bucherei, Volume 602. Andreas Arnold." Quarterly Review of Biology 66, no. 2 (1991): 226–27. http://dx.doi.org/10.1086/417209.

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2

Wilson, John R. U., Pablo García-Díaz, Phillip Cassey, David M. Richardson, Petr Pyšek, and Tim M. Blackburn. "Biological invasions and natural colonisations are different – the need for invasion science." NeoBiota 31 (September 14, 2016): 87–98. https://doi.org/10.3897/neobiota.31.9185.

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Abstract (sommario):
In a recent Discussion Paper, Hoffmann and Courchamp (2016) posed the question: are biological invasions and natural colonisations that different? This apparently simple question resonates at the core of the biological study of human-induced global change, and we strongly believe that the answer is yes: biological invasions and natural colonisations differ in processes and mechanisms in ways that are crucial for science, management, and policy. Invasion biology has, over time, developed into the broader transdisciplinary field of invasion science. At the heart of invasion science is the realis
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3

Vrbničanin, Sava, and Dragana Božić. "Biological invasions: The example of weed species." Acta herbologica 23, no. 2 (2014): 97–112. http://dx.doi.org/10.5937/actaherb1402097v.

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4

Romanuk, Tamara N., Yun Zhou, Ulrich Brose, Eric L. Berlow, Richard J. Williams, and Neo D. Martinez. "Predicting invasion success in complex ecological networks." Philosophical Transactions of the Royal Society B: Biological Sciences 364, no. 1524 (2009): 1743–54. http://dx.doi.org/10.1098/rstb.2008.0286.

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A central and perhaps insurmountable challenge of invasion ecology is to predict which combinations of species and habitats most effectively promote and prevent biological invasions. Here, we integrate models of network structure and nonlinear population dynamics to search for potential generalities among trophic factors that may drive invasion success and failure. We simulate invasions where 100 different species attempt to invade 150 different food webs with 15–26 species and a wide range (0.06–0.32) of connectance. These simulations yield 11 438 invasion attempts by non-basal species, 47 pe
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5

Ingenloff, Kathryn, Christopher M. Hensz, Tashitso Anamza, et al. "Predictable invasion dynamics in North American populations of the Eurasian collared dove Streptopelia decaocto." Proceedings of the Royal Society B: Biological Sciences 284, no. 1862 (2017): 20171157. http://dx.doi.org/10.1098/rspb.2017.1157.

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Species invasions represent a significant dimension of global change yet the dynamics of invasions remain poorly understood and are considered rather unpredictable. We explored interannual dynamics of the invasion process in the Eurasian collared dove ( Streptopelia decaocto ) and tested whether the advance of the invasion front of the species in North America relates to centrality (versus peripherality) within its estimated fundamental ecological niche. We used ecological niche modelling approaches to estimate the dimensions of the fundamental ecological niche on the Old World distribution of
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6

Yang, Tianjie, Gang Han, Qingjun Yang, et al. "Resource stoichiometry shapes community invasion resistance via productivity-mediated species identity effects." Proceedings of the Royal Society B: Biological Sciences 285, no. 1893 (2018): 20182035. http://dx.doi.org/10.1098/rspb.2018.2035.

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Diversity–invasion resistance relationships are often variable and sensitive to environmental conditions such as resource availability. Resource stoichiometry, the relative concentration of different elements in the environment, has been shown to have strong effects on the physiology and interactions between different species. Yet, its role for diversity–invasion resistance relationships is still poorly understood. Here, we explored how the ratio of nitrogen (N) and phosphorus affects the productivity and invasion resistance of constructed microbial communities by a plant pathogenic bacterium,
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7

Keenan, Vincent A., and Stephen J. Cornell. "Anomalous invasion dynamics due to dispersal polymorphism and dispersal–reproduction trade-offs." Proceedings of the Royal Society B: Biological Sciences 288, no. 1942 (2021): 20202825. http://dx.doi.org/10.1098/rspb.2020.2825.

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Dispersal polymorphism and mutation play significant roles during biological invasions, potentially leading to evolution and complex behaviour such as accelerating or decelerating invasion fronts. However, life-history theory predicts that reproductive fitness—another key determinant of invasion dynamics—may be lower for more dispersive strains. Here, we use a mathematical model to show that unexpected invasion dynamics emerge from the combination of heritable dispersal polymorphism, dispersal-fitness trade-offs, and mutation between strains. We show that the invasion dynamics are determined b
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8

Manus, Jean-Marie. "Des analyses de biologie pour remplacer les explorations invasives." Revue Française des Laboratoires 2001, no. 338 (2001): 14. http://dx.doi.org/10.1016/s0338-9898(01)80328-0.

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9

Enders, Martin, Frank Havemann, and Jonathan M. Jeschke. "A citation-based map of concepts in invasion biology." NeoBiota 47 (June 19, 2019): 23–42. https://doi.org/10.3897/neobiota.47.32608.

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Abstract (sommario):
Invasion biology has been quickly expanding in the last decades so that it is now metaphorically flooded with publications, concepts, and hypotheses. Among experts, there is no clear consensus about the relationships between invasion concepts, and almost no one seems to have a good overview of the literature anymore. Similar observations can be made for other research fields. Science needs new navigation tools so that researchers within and outside of a research field as well as science journalists, students, teachers, practitioners, policy-makers, and others interested in the field can more e
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10

Derham, Tristan T., Richard P. Duncan, Christopher N. Johnson, and Menna E. Jones. "Hope and caution: rewilding to mitigate the impacts of biological invasions." Philosophical Transactions of the Royal Society B: Biological Sciences 373, no. 1761 (2018): 20180127. http://dx.doi.org/10.1098/rstb.2018.0127.

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Rewilding is a novel approach to ecological restoration. Trophic rewilding in particular aims to reinstate ecological functions, especially trophic interactions, through the introduction of animals. We consider the potential for trophic rewilding to address biological invasions. In this broad review, we note some of the important conceptual and ethical foundations of rewilding, including a focus on ecosystem function rather than composition, reliance on animal agency, and an appeal to an ethic of coexistence. Second, we use theory from invasion biology to highlight pathways by which rewilding
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11

Neelam Das, Pavan Kumar Addanki. "A Clinical and Radiographic Study Evaluated the Biologic Width of the Periodontium in Individuals with Healthy Periodontitis, Generalized Chronic Periodontitis and Generalized Aggressive Periodontitis." Tuijin Jishu/Journal of Propulsion Technology 44, no. 4 (2023): 7478–83. http://dx.doi.org/10.52783/tjjpt.v44.i4.2598.

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The progression of periodontal destruction is generally considered to be chronic in nature and slowly progressing. This study was to correlate radiographic examination with the clinical periodontal condition in cases of biologic width in subjects with healthy periodontium,generalized chronic periodontitis and generalized aggressive periodontitisclinically and radiographically. Subjects between the age group of 20 and 45 years were screened. About10 patients each with healthy periodontium,subjects with generalized chronic periodontitis and generalized aggressive periodontitis were selected.The
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12

Florance, Daniel, Jonathan K. Webb, Tim Dempster, Michael R. Kearney, Alex Worthing, and Mike Letnic. "Excluding access to invasion hubs can contain the spread of an invasive vertebrate." Proceedings of the Royal Society B: Biological Sciences 278, no. 1720 (2011): 2900–2908. http://dx.doi.org/10.1098/rspb.2011.0032.

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Many biological invasions do not occur as a gradual expansion along a continuous front, but result from the expansion of satellite populations that become established at ‘invasion hubs’. Although theoretical studies indicate that targeting control efforts at invasion hubs can effectively contain the spread of invasions, few studies have demonstrated this in practice. In arid landscapes worldwide, humans have increased the availability of surface water by creating artificial water points (AWPs) such as troughs and dams for livestock. By experimentally excluding invasive cane toads ( Bufo marinu
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13

Schmidt, Lindsay, and Jeffrey Myers. "Bronchioloalveolar Carcinoma and the Significance of Invasion: Predicting Biologic Behavior." Archives of Pathology & Laboratory Medicine 134, no. 10 (2010): 1450–54. http://dx.doi.org/10.5858/2010-0227-cr.1.

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Abstract A resected adenocarcinoma illustrates challenges in diagnosing bronchioloalveolar carcinoma (BAC). Bronchioloalveolar carcinoma is defined by lack of invasion, something that may be difficult to assess in scars. Small (≤0.5 cm) invasive foci have little impact on the good prognosis associated with low-stage tumors. The term microinvasive adenocarcinoma or minimally invasive adenocarcinoma has been proposed for otherwise typical BACs and small invasive foci measuring 0.5 cm or less. Larger areas of invasion are associated with a more aggressive course and more reliably distinguish BAC
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14

Mikkelsen, Tom. "Cytostatic Agents in the Management of Malignant Gliomas." Cancer Control 5, no. 2 (1998): 150–62. http://dx.doi.org/10.1177/107327489800500206.

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Background: Cytotoxic therapy for malignant gliomas is limited by poor delivery and drug resistance, and local therapy is ineffective in managing migratory cells. However, recent developments in malignant glioma therapy involve trials of cytostatic rather than conventional cytotoxic agents. Methods: The biology of the brain extracellular matrix, tumor invasion, and angiogenesis are reviewed, and the cytostatic agents that inhibit matrix metalloproteinases, angiogenesis, cell proliferation, and signal transduction are discussed, as well as studies of the angiogenic and migratory capacity of mal
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15

Strona, Giovanni, Corey J. A. Bradshaw, Pedro Cardoso, et al. "Time-travelling pathogens and their risk to ecological communities." PLOS Computational Biology 19, no. 7 (2023): e1011268. http://dx.doi.org/10.1371/journal.pcbi.1011268.

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Permafrost thawing and the potential ‘lab leak’ of ancient microorganisms generate risks of biological invasions for today’s ecological communities, including threats to human health via exposure to emergent pathogens. Whether and how such ‘time-travelling’ invaders could establish in modern communities is unclear, and existing data are too scarce to test hypotheses. To quantify the risks of time-travelling invasions, we isolated digital virus-like pathogens from the past records of coevolved artificial life communities and studied their simulated invasion into future states of the community.
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16

Coakley, Stephanie, and Carloalberto Petti. "Impacts of the Invasive Impatiens glandulifera: Lessons Learned from One of Europe’s Top Invasive Species." Biology 10, no. 7 (2021): 619. http://dx.doi.org/10.3390/biology10070619.

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Biological invasions are renowned for their negative ecological and economic implications, however from studying invasions invaluable insights can be gained in the fields of ecology and evolution- potentially contributing towards conservation plans to deal, not only with biological invasion, but with other concerning issues, such as climate change. Impatiens glandulifera, or Himalayan balsam, is widely considered to be a highly problematic invasive, having spread across more than thirty countries during the past century. This paper will examine the findings which have arose from studying I. gl
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17

Northfield, Tobin D., Susan G. W. Laurance, Margaret M. Mayfield, et al. "Native turncoats and indirect facilitation of species invasions." Proceedings of the Royal Society B: Biological Sciences 285, no. 1871 (2018): 20171936. http://dx.doi.org/10.1098/rspb.2017.1936.

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At local scales, native species can resist invasion by feeding on and competing with would-be invasive species. However, this relationship tends to break down or reverse at larger scales. Here, we consider the role of native species as indirect facilitators of invasion and their potential role in this diversity-driven ‘invasion paradox’. We coin the term ‘native turncoats’ to describe native facilitators of non-native species and identify eight ways they may indirectly facilitate species invasion. Some are commonly documented, while others, such as indirect interactions within competitive comm
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18

Kurkjian, Helen M., M. Javad Akbari, and Babak Momeni. "The impact of interactions on invasion and colonization resistance in microbial communities." PLOS Computational Biology 17, no. 1 (2021): e1008643. http://dx.doi.org/10.1371/journal.pcbi.1008643.

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In human microbiota, the prevention or promotion of invasions can be crucial to human health. Invasion outcomes, in turn, are impacted by the composition of resident communities and interactions of resident members with the invader. Here we study how interactions influence invasion outcomes in microbial communities, when interactions are primarily mediated by chemicals that are released into or consumed from the environment. We use a previously developed dynamic model which explicitly includes species abundances and the concentrations of chemicals that mediate species interaction. Using this m
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19

Daly, Ella Z., Hannah Sørine Gerlich, Yves Frenot, Toke T. Høye, Martin Holmstrup, and David Renault. "Climate Change Helps Polar Invasives Establish and Flourish: Evidence from Long-Term Monitoring of the Blowfly Calliphora vicina." Biology 12, no. 1 (2023): 111. http://dx.doi.org/10.3390/biology12010111.

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The isolated sub-Antarctic islands are of major ecological interest because of their unique species diversity and long history of limited human disturbance. However, since the presence of Europeans, these islands and their sensitive biota have been under increasing pressure due to human activity and associated biological invasions. In such delicate ecosystems, biological invasions are an exceptional threat that may be further amplified by climate change. We examined the invasion trajectory of the blowfly Calliphora vicina (Robineau-Desvoidy 1830). First introduced in the sub-Antarctic Kerguele
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20

Goldstein, Joshua, Jaewoo Park, Murali Haran, Andrew Liebhold, and Ottar N. Bjørnstad. "Quantifying spatio-temporal variation of invasion spread." Proceedings of the Royal Society B: Biological Sciences 286, no. 1894 (2019): 20182294. http://dx.doi.org/10.1098/rspb.2018.2294.

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— The spread of invasive species can have far-reaching environmental and ecological consequences. Understanding invasion spread patterns and the underlying process driving invasions are key to predicting and managing invasions. — We combine a set of statistical methods in a novel way to characterize local spread properties and demonstrate their application using simulated and historical data on invasive insects. Our method uses a Gaussian process fit to the surface of waiting times to invasion in order to characterize the vector field of spread. — Using this method, we estimate with statistica
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21

Chand, M. T., K. Stashek, E. E. Furth, R. Tondon, and A. Al Zeer. "The Biologic Diversity of Colorectal Carcinoma (CRC) is Present in the Early Stage: Quantitative Analysis of Malignant Polyps." American Journal of Clinical Pathology 160, Supplement_1 (2023): S31—S32. http://dx.doi.org/10.1093/ajcp/aqad150.069.

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Abstract Introduction/Objective Risk factors in malignant polyps to predict recurrence in T1 colorectal carcinoma (CRC) include depth of invasion, margin status, lymphovascular invasion, tumor differentiation and budding. However, the effect of other factors, such as tumor volume and tumor cellularity, are not well studied. We quantitatively, using image analysis, determined the strength and interdependence of the depth of invasion, margin status, tumor volume and tumor cell density on the probability of having residual adenocarcinoma on resection and long term patient outcomes. Methods/Case R
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22

Heiss, Kirsten, Hui Nie, Sumit Kumar, Thomas M. Daly, Lawrence W. Bergman, and Kai Matuschewski. "Functional Characterization of a Redundant Plasmodium TRAP Family Invasin, TRAP-Like Protein, by Aldolase Binding and a Genetic Complementation Test." Eukaryotic Cell 7, no. 6 (2008): 1062–70. http://dx.doi.org/10.1128/ec.00089-08.

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ABSTRACT Efficient and specific host cell entry is of exquisite importance for intracellular pathogens. Parasites of the phylum Apicomplexa are highly motile and actively enter host cells. These functions are mediated by type I transmembrane invasins of the TRAP family that link an extracellular recognition event to the parasite actin-myosin motor machinery. We systematically tested potential parasite invasins for binding to the actin bridging molecule aldolase and complementation of the vital cytoplasmic domain of the sporozoite invasin TRAP. We show that the ookinete invasin CTRP and a novel
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23

Taguchi, CMC, JK Bernardon, G. Zimmermann, and LN Baratieri. "Tooth Fragment Reattachment: A Case Report." Operative Dentistry 40, no. 3 (2015): 227–34. http://dx.doi.org/10.2341/14-034-t.

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SUMMARY The aim of this article is to present a case report for the multidisciplinary treatment of anterior tooth fractures with invasion of the biologic width and pulpectomy. Successful esthetic and functional results were achieved by bonding the crown fragment, without any form of preparation or the utilization of intracanal posts.
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24

Botella, Christophe, Pierre Bonnet, Cang Hui, Alexis Joly, and David M. Richardson. "Dynamic Species Distribution Modeling Reveals the Pivotal Role of Human-Mediated Long-Distance Dispersal in Plant Invasion." Biology 11, no. 9 (2022): 1293. http://dx.doi.org/10.3390/biology11091293.

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Plant invasions generate massive ecological and economic costs worldwide. Predicting their spatial dynamics is crucial to the design of effective management strategies and the prevention of invasions. Earlier studies highlighted the crucial role of long-distance dispersal in explaining the speed of many invasions. In addition, invasion speed depends highly on the duration of its lag phase, which may depend on the scaling of fecundity with age, especially for woody plants, even though empirical proof is still rare. Bayesian dynamic species distribution models enable the fitting of process-based
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25

Hegedüšová, Katarína, and Eduardo Cires. "Call for SI in Biologia Biological invasions in the 21st century: a global risk." IAVS Bulletin 2021, no. 3 (2021): 23. http://dx.doi.org/10.21570/bul-202103-8.

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26

Lemarchand, M., M. Lefebvre, M. Kempf, et al. "Apport de la biologie moléculaire pour le diagnostic des infections invasives à méningocoques." Médecine et Maladies Infectieuses 48, no. 4 (2018): S121. http://dx.doi.org/10.1016/j.medmal.2018.04.304.

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Rivoire, Waldemar Augusto, Helena Von Eye Corleta, Ilma Simoni Brum, and Edison Capp. "Biologia molecular do câncer cervical." Revista Brasileira de Saúde Materno Infantil 6, no. 4 (2006): 447–51. http://dx.doi.org/10.1590/s1519-38292006000400012.

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A carcinogênese é um processo de múltiplas etapas. Alterações no equilíbrio citogenético ocorrem na transformação do epitélio normal a câncer cervical. Numerosos estudos apoiam a hipótese de que a infecção por HPV está associada com o desenvolvimento de alterações malignas e pré-malignas do trato genital inferior. Neste trabalho são apresentadas as bases para a compreensão da oncogênese cervical. O ciclo celular é controlado por proto-oncogenes e genes supressores. Quando ocorrem mutações, proto-oncogenes tornam-se oncogenes, que são carcinogênicos e causam multiplicação celular excessiva. A p
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28

Leung, Brian, and Nicholas E. Mandrak. "The risk of establishment of aquatic invasive species: joining invasibility and propagule pressure." Proceedings of the Royal Society B: Biological Sciences 274, no. 1625 (2007): 2603–9. http://dx.doi.org/10.1098/rspb.2007.0841.

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Invasive species are increasingly becoming a policy priority. This has spurred researchers and managers to try to estimate the risk of invasion. Conceptually, invasions are dependent both on the receiving environment (invasibility) and on the ability to reach these new areas (propagule pressure). However, analyses of risk typically examine only one or the other. Here, we develop and apply a joint model of invasion risk that simultaneously incorporates invasibility and propagule pressure. We present arguments that the behaviour of these two elements of risk differs substantially—propagule press
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Anisuzzaman, Md, Nazmul Hosain, and Zulfiqar Rashid. "Renal Cell Carcinoma with Inferior Vena Cava Thrombus: A Case Report." Cardiovascular Journal 15, no. 1 (2022): 111–15. http://dx.doi.org/10.3329/cardio.v15i1.61921.

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The incidence of venous extension to the inferior vena cava (IVC) of renal cell carcinoma (RCC) is markedly increased recently mostly due to the advances in diagnostic modalities. Such vascular invasion implies a heightened biologic behavior and a surgical challenge during the course of treatment. Here we discussed a case with study of the classification guidelines, recent diagnostic tools and up-to-date therapeutic modalities for RCC with IVC tumor thrombi. Also added to the discussion are the prognostic significance regarding the pathologic nature of vascular invasion, cephalad extent of thr
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Gorby, Gary L., Edward N. Robinson Jr., Lee R. Barley, Christopher M. Clemens, and Zell A. McGee. "Microbial invasion: a covert activity?" Canadian Journal of Microbiology 34, no. 4 (1988): 507–12. http://dx.doi.org/10.1139/m88-087.

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In contrast to nonpathogenic microorganisms that exist happily in biofilms on various organic and inorganic surfaces, many pathogenic microbes have the additional ability to invade host tissues by inducing their own endocytosis and transport across normally protective barriers. This phenomenon, designated " parasite-directed endocytosis," has been observed with a variety of surfaces (intestinal, genital, nasopharyngeal, and tracheal epithelium) as well as in endothelial cells. The mechanisms involved in invasion may involve a single factor as described for some species of Yersinia, or may requ
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Hudson, Cameron M., Marta Vidal-García, Trevor G. Murray, and Richard Shine. "The accelerating anuran: evolution of locomotor performance in cane toads ( Rhinella marina , Bufonidae) at an invasion front." Proceedings of the Royal Society B: Biological Sciences 287, no. 1938 (2020): 20201964. http://dx.doi.org/10.1098/rspb.2020.1964.

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As is common in biological invasions, the rate at which cane toads ( Rhinella marina ) have spread across tropical Australia has accelerated through time. Individuals at the invasion front travel further than range-core conspecifics and exhibit distinctive morphologies that may facilitate rapid dispersal. However, the links between these morphological changes and locomotor performance have not been clearly documented. We used raceway trials and high-speed videography to document locomotor traits (e.g. hop distances, heights, velocities, and angles of take-off and landing) of toads from range-c
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Mounger, Jeannie, Malika L. Ainouche, Oliver Bossdorf, et al. "Epigenetics and the success of invasive plants." Philosophical Transactions of the Royal Society B: Biological Sciences 376, no. 1826 (2021): 20200117. http://dx.doi.org/10.1098/rstb.2020.0117.

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Biological invasions impose ecological and economic problems on a global scale, but also provide extraordinary opportunities for studying contemporary evolution. It is critical to understand the evolutionary processes that underly invasion success in order to successfully manage existing invaders, and to prevent future invasions. As successful invasive species sometimes are suspected to rapidly adjust to their new environments in spite of very low genetic diversity, we are obliged to re-evaluate genomic-level processes that translate into phenotypic diversity. In this paper, we review work tha
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Nelson, Amy R., Barbara Fingleton, Mace L. Rothenberg, and Lynn M. Matrisian. "Matrix Metalloproteinases: Biologic Activity and Clinical Implications." Journal of Clinical Oncology 18, no. 5 (2000): 1135. http://dx.doi.org/10.1200/jco.2000.18.5.1135.

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ABSTRACT: Tumor progression is a complex, multistage process by which a normal cell undergoes genetic changes that result in phenotypic alterations and the acquisition of the ability to spread and colonize distant sites in the body. Although many factors regulate malignant tumor growth and spread, interactions between a tumor and its surrounding microenvironment result in the production of important protein products that are crucial to each step of tumor progression. The matrix metalloproteinases (MMPs) are a family of degradative enzymes with clear links to malignancy. These enzymes are assoc
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Olazcuaga, Laure, Anne Loiseau, Hugues Parrinello, et al. "A Whole-Genome Scan for Association with Invasion Success in the Fruit Fly Drosophila suzukii Using Contrasts of Allele Frequencies Corrected for Population Structure." Molecular Biology and Evolution 37, no. 8 (2020): 2369–85. http://dx.doi.org/10.1093/molbev/msaa098.

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Abstract Evidence is accumulating that evolutionary changes are not only common during biological invasions but may also contribute directly to invasion success. The genomic basis of such changes is still largely unexplored. Yet, understanding the genomic response to invasion may help to predict the conditions under which invasiveness can be enhanced or suppressed. Here, we characterized the genome response of the spotted wing drosophila Drosophila suzukii during the worldwide invasion of this pest insect species, by conducting a genome-wide association study to identify genes involved in adap
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Biswas, Tithi, Charulata Jindal, Timothy L. Fitzgerald, and Jimmy T. Efird. "Pathologic Complete Response (pCR) and Survival of Women with Inflammatory Breast Cancer (IBC): An Analysis Based on Biologic Subtypes and Demographic Characteristics." International Journal of Environmental Research and Public Health 16, no. 1 (2019): 124. http://dx.doi.org/10.3390/ijerph16010124.

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In this US-based study of the National Cancer Database (NCDB), we examined 8550 patients diagnosed with non-metastatic, invasive inflammatory breast cancer (IBC) who received surgery from 2004–2013. Patients were grouped into four biologic subtypes (HR+/HER2−, HR+/HER2+, HR−/HER2+, HR−/HER2−). On average, women were 56 years of age at diagnosis and were followed for a median of 3.7 years. The majority were white (80%), had private health insurance (50%), and presented with poorly differentiated tumors (57%). Approximately 46% of the cancers were >5 cm. Most patients underwent mastectomy (94
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Spring, Kathleen, Catherine Chabot, Simon Langlois, et al. "Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation." Blood 120, no. 13 (2012): 2745–56. http://dx.doi.org/10.1182/blood-2011-12-398040.

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Abstract DEP-1/CD148 is a receptor-like protein tyrosine phosphatase with antiproliferative and tumor-suppressive functions. Interestingly, it also positively regulates Src family kinases in hematopoietic and endothelial cells, where we showed it promotes VE-cadherin–associated Src activation and endothelial cell survival upon VEGF stimulation. However, the molecular mechanism involved and its biologic functions in endothelial cells remain ill-defined. We demonstrate here that DEP-1 is phosphorylated in a Src- and Fyn-dependent manner on Y1311 and Y1320, which bind the Src SH2 domain. This all
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Miller, Corrie B., and Tricia Wright. "Investigating Mechanisms of Stillbirth in the Setting of Prenatal Substance Use." Academic Forensic Pathology 8, no. 4 (2018): 865–73. http://dx.doi.org/10.1177/1925362118821471.

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Abstract (sommario):
Introduction: Intrauterine fetal demise affects between 0.4-0.8% of pregnancies worldwide. This significant adverse pregnancy outcome continues to be poorly understood. In utero exposure to substances increases the risk of stillbirth to varying degrees according to the type of substance and degree of exposure. The aim of this qualitative narrative review is to investigate common biologic relationships between stillbirth and maternal substance use. Methods: A PubMed literature search was conducted to query the most commonly used substances and biologic mechanisms of stillbirth. Search terms inc
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Liu, Ren, Ming Gong, Xiuqing Li, et al. "Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma." Blood 116, no. 2 (2010): 297–305. http://dx.doi.org/10.1182/blood-2009-12-257154.

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Abstract (sommario):
AbstractAxl is an oncogenic receptor tyrosine kinase that plays multiple roles in tumorigenesis and metastasis of many cancers. This study is the first to demonstrate that Axl is induced in Kaposi sarcoma and Kaposi sarcoma herpesvirus (KSHV) transformed endothelial cells. Conditionally, expression of one KSHV latency protein vFLIP induces Axl expression in endothelial cells. This induction can be blocked by nuclear factor-κB inhibitor, consistent with the known vFLIP mechanism of action. KS cell lines lacking KSHV also have elevated Axl expression, which probably resulted from hypomethylation
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39

Kwiecien, Jacek M., Liqiang Zhang, Jordan R. Yaron, et al. "Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function." Journal of Clinical Medicine 9, no. 4 (2020): 1221. http://dx.doi.org/10.3390/jcm9041221.

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Abstract (sommario):
Spinal cord injury (SCI) results in massive secondary damage characterized by a prolonged inflammation with phagocytic macrophage invasion and tissue destruction. In prior work, sustained subdural infusion of anti-inflammatory compounds reduced neurological deficits and reduced pro-inflammatory cell invasion at the site of injury leading to improved outcomes. We hypothesized that implantation of a hydrogel loaded with an immune modulating biologic drug, Serp-1, for sustained delivery after crush-induced SCI would have an effective anti-inflammatory and neuroprotective effect. Rats with dorsal
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40

Kaya, Oskay, Engin Olcucuoglu, Gaye Seker, and Hakan Kulacoglu. "Instant Abdominal Wall Reconstruction with Biologic Mesh following Resection of Locally Advanced Colonic Cancer." Case Reports in Medicine 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/959342.

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We present a case of immediate abdominal wall reconstruction with biologic mesh following the resection of locally advanced colonic cancer. The tumor in the right colon did not respond to neoadjuvant chemotherapy. Surgical enbloc excision, including excision of the invasion in the abdominal wall, was achieved, and the defect was reconstructed with porcine dermal collagen mesh. The patient was discharged with no complication, and adaptation of the mesh was excellent at the six-month followup.
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Nouh, Mohammed Ahmed Abdel-Muneem, Masashi Inui, and Yoshiyuki Kakehi. "Renal Cell Carcinoma with IVC Thrombi; Current Concepts and Future Perspectives." Clinical medicine. Oncology 2 (January 2008): CMO.S464. http://dx.doi.org/10.4137/cmo.s464.

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Abstract (sommario):
The incidence of venous extension to the inferior vena cava (IVC) in renal cell carcinoma (RCC) is markedly increased recently mostly due to the advances in diagnostic modalities. Such vascular invasion implies a heightened biologic behavior and a surgical challenge during the course of treatment. In this study, we reviewed the classification guidelines, recent diagnostic tools and up-to-date therapeutic modalities for RCC with IVC tumor thrombi added to the prognostic significance regarding the pathologic nature of vascular invasion; cephalad extent of thrombi and any associated distant metas
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42

Osek, Jacek, and Kinga Wieczorek. "Listeria monocytogenes—How This Pathogen Uses Its Virulence Mechanisms to Infect the Hosts." Pathogens 11, no. 12 (2022): 1491. http://dx.doi.org/10.3390/pathogens11121491.

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Abstract (sommario):
Listeriosis is a serious food-borne illness, especially in susceptible populations, including children, pregnant women, and elderlies. The disease can occur in two forms: non-invasive febrile gastroenteritis and severe invasive listeriosis with septicemia, meningoencephalitis, perinatal infections, and abortion. Expression of each symptom depends on various bacterial virulence factors, immunological status of the infected person, and the number of ingested bacteria. Internalins, mainly InlA and InlB, invasins (invasin A, LAP), and other surface adhesion proteins (InlP1, InlP4) are responsible
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43

Kühn, Ingolf, Ingo Kowarik, Johannes Kollmann, et al. "Open minded and open access: introducing NeoBiota, a new peer-reviewed journal of biological invasions." NeoBiota 9 (August 11, 2011): 1–12. https://doi.org/10.3897/neobiota.9.1835.

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Abstract (sommario):
The Editorial presents the focus, scope, policies, and the inaugural issue of NeoBiota, a new open access peer-reviewed journal of biological invasions. The new journal NeoBiota is a continuation of the former NEOBIOTA publication series. The journal will deal with all aspects of invasion biology and impose no restrictions on manuscript size neither on use of color. NeoBiota implies an XML-based editorial workflow and several cutting-edge innovations in publishing and dissemination, such as semantic markup of and enhancements to published texts, data publication, and extensive cross-linking wi
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44

Xu, Junwei, Ning Qin, Wenbo Jiang, and Tao Chen. "Erianin Regulates PI3K/AKT Signaling Pathway and Inhibits Cell Invasion and Migration in Gastric Cancer In Vitro." Current Topics in Nutraceutical Research 20, no. 3 (2022): 492–97. http://dx.doi.org/10.37290/ctnr2641-452x.20:492-497.

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Abstract (sommario):
Gastric carcinoma is one of the most malignant cancers associated with lifestyle and genetics. The currently used pharmacotherapeutics are associated with serious side effects necessitating a need for safer drugs. Erianin is a natural plant bioactive substance known for its anti-cancerous and a variety of other biologic activities. Using a variety of measures such as colony formation, invasion and migration assay, and flow cytometry and apoptosis, we have examined the effect of erianin on human gastric adenocarcinoma cells representing gastric carcinoma. The results show that erianin ensured (
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45

Xu, Junwei, Ning Qin, Wenbo Jiang, and Tao Chen. "Erianin Regulates PI3K/AKT Signaling Pathway and Inhibits Cell Invasion and Migration in Gastric Cancer In Vitro." Current Topics in Nutraceutical Research 20, no. 3 (2022): 492–97. http://dx.doi.org/10.37290/ctnr2641-452x.20:492-497.

Testo completo
Abstract (sommario):
Gastric carcinoma is one of the most malignant cancers associated with lifestyle and genetics. The currently used pharmacotherapeutics are associated with serious side effects necessitating a need for safer drugs. Erianin is a natural plant bioactive substance known for its anti-cancerous and a variety of other biologic activities. Using a variety of measures such as colony formation, invasion and migration assay, and flow cytometry and apoptosis, we have examined the effect of erianin on human gastric adenocarcinoma cells representing gastric carcinoma. The results show that erianin ensured (
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46

Almberg, Emily S., Paul C. Cross, Andrew P. Dobson, Douglas W. Smith, and Peter J. Hudson. "Parasite invasion following host reintroduction: a case study of Yellowstone's wolves." Philosophical Transactions of the Royal Society B: Biological Sciences 367, no. 1604 (2012): 2840–51. http://dx.doi.org/10.1098/rstb.2011.0369.

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Abstract (sommario):
Wildlife reintroductions select or treat individuals for good health with the expectation that these individuals will fare better than infected animals. However, these individuals, new to their environment, may also be particularly susceptible to circulating infections and this may result in high morbidity and mortality, potentially jeopardizing the goals of recovery. Here, using the reintroduction of the grey wolf ( Canis lupus ) into Yellowstone National Park as a case study, we address the question of how parasites invade a reintroduced population and consider the impact of these invasions
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47

Metzcar, John, Yafei Wang, Randy Heiland, and Paul Macklin. "A Review of Cell-Based Computational Modeling in Cancer Biology." JCO Clinical Cancer Informatics, no. 3 (December 2019): 1–13. http://dx.doi.org/10.1200/cci.18.00069.

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Abstract (sommario):
Cancer biology involves complex, dynamic interactions between cancer cells and their tissue microenvironments. Single-cell effects are critical drivers of clinical progression. Chemical and mechanical communication between tumor and stromal cells can co-opt normal physiologic processes to promote growth and invasion. Cancer cell heterogeneity increases cancer’s ability to test strategies to adapt to microenvironmental stresses. Hypoxia and treatment can select for cancer stem cells and drive invasion and resistance. Cell-based computational models (also known as discrete models, agent-based mo
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48

Zhang, Xiaojuan, Guoyan Wang, Peihao Peng, et al. "Influences of environment, human activity, and climate on the invasion of Ageratina adenophora (Spreng.) in Southwest China." PeerJ 11 (March 9, 2023): e14902. http://dx.doi.org/10.7717/peerj.14902.

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Abstract (sommario):
With economic and social globalization, invasive alien species have significantly threatened local ecological security. Identifying the invasive mechanisms of invasive alien species can aid in preventing species invasions and protecting local ecological and economic security. As a globally invasive plant, Ageratina adenophora (Asteraceae) has spread to many parts of the world and had a seriously impacted the ecology and economy of its invaded areas. Using observational data and Landsat OLI images in an arid valley region in southwest China, this study examined how climate, human activity and e
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49

Medina Villaamil, Vanessa, Guadalupe Aparicio Gallego, Francisco Gomez Veiga, et al. "Using biologic knowledge to discover molecular correlations between human renal cell carcinoma pathways." Journal of Clinical Oncology 32, no. 4_suppl (2014): 451. http://dx.doi.org/10.1200/jco.2014.32.4_suppl.451.

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Abstract (sommario):
451 Background: Renal cell carcinoma (RCC) is known to be resistant to chemotherapy. There is need for the identification of biomarkers capable to determine RCC prognosis factors and metastatic potential obtainable from non-invasive or minimally invasive techniques. Our aim was to derive predictive models which could predict more accurately than any one factor alone. Methods: To studythe cascade of events leading to the formation and progression of RCC, we assessed 29 markers by immunohistochemistry and qRT-PCR using tissue micro-array (TMA). Results: Multivariate logistic regression showed th
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50

Clark, Gregory W., and Elisabeth R. M. Tillier. "Loss and gain of GroEL in the MollicutesThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process." Biochemistry and Cell Biology 88, no. 2 (2010): 185–94. http://dx.doi.org/10.1139/o09-157.

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Abstract (sommario):
GroEL is a chaperone thought of as essential for bacterial life. However, some species of Mollicutes are missing GroEL. We use phylogenetic analysis to show that the presence of GroEL is polyphyletic among the Mollicutes, and that there is evidence for lateral gene transfer of GroEL to Mycoplasma penetrans from the Proteobacteria. Furthermore, we propose that the presence of GroEL in Mycoplasma may be required for invasion of host tissue, suggesting that GroEL may act as an adhesin–invasin.
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