Bibliografie tematiche / Biosynthesis

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Letteratura scientifica selezionata sul tema "Biosynthesis"

Autore: Grafiati
Pubblicato: 4 giugno 2021
Ultima modifica: 25 luglio 2025

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Articoli di riviste sul tema "Biosynthesis"

1

Nishida, Hiromi, and Makoto Nishiyama. "Evolution of Lysine Biosynthesis in the Phylum Deinococcus-Thermus." International Journal of Evolutionary Biology 2012 (May 8, 2012): 1–6. http://dx.doi.org/10.1155/2012/745931.

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Abstract (sommario):
Thermus thermophilus biosynthesizes lysine through the α-aminoadipate (AAA) pathway: this observation was the first discovery of lysine biosynthesis through the AAA pathway in archaea and bacteria. Genes homologous to the T. thermophilus lysine biosynthetic genes are widely distributed in bacteria of the Deinococcus-Thermus phylum. Our phylogenetic analyses strongly suggest that a common ancestor of the Deinococcus-Thermus phylum had the ancestral genes for bacterial lysine biosynthesis through the AAA pathway. In addition, our findings suggest that the ancestor lacked genes for lysine biosynt
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2

Pulsawat, Nattika, Shigeru Kitani, Eriko Fukushima, and Takuya Nihira. "Hierarchical control of virginiamycin production in Streptomyces virginiae by three pathway-specific regulators: VmsS, VmsT and VmsR." Microbiology 155, no. 4 (2009): 1250–59. http://dx.doi.org/10.1099/mic.0.022467-0.

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Abstract (sommario):
Two regulatory genes encoding a Streptomyces antibiotic regulatory protein (vmsS) and a response regulator (vmsT) of a bacterial two-component signal transduction system are present in the left-hand region of the biosynthetic gene cluster of the antibiotic virginiamycin, which is composed of virginiamycin M (VM) and virginiamycin S (VS), in Streptomyces virginiae. Disruption of vmsS abolished both VM and VS biosynthesis, with drastic alteration of the transcriptional profile for virginiamycin biosynthetic genes, whereas disruption of vmsT resulted in only a loss of VM biosynthesis, suggesting
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3

Moore, Bradley. "Asymmetric Alkene and Arene Halofunctionalization Reactions in Meroterpenoid Biosynthesis." Synlett 29, no. 04 (2017): 401–9. http://dx.doi.org/10.1055/s-0036-1590919.

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Abstract (sommario):
Meroterpenoid natural products are important bioactive molecules with broad distribution throughout nature. In Streptomyces bacteria, naphthoquinone-based meroterpenoids comprise a simple yet structurally fascinating group of natural product antibiotics that are enzymatically constructed through a series of asymmetric alkene and arene halofunctionalization reactions. This account article highlights our discovery and characterization of a group of vanadium-dependent chloroperoxidase enzymes that catalyze halogen-assisted cyclization and rearrangement reactions and have inspired biomimetic synth
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Araki, Yasuko, Takayoshi Awakawa, Motomichi Matsuzaki, et al. "Complete biosynthetic pathways of ascofuranone and ascochlorin inAcremonium egyptiacum." Proceedings of the National Academy of Sciences 116, no. 17 (2019): 8269–74. http://dx.doi.org/10.1073/pnas.1819254116.

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Ascofuranone (AF) and ascochlorin (AC) are meroterpenoids produced by various filamentous fungi, includingAcremonium egyptiacum(synonym:Acremonium sclerotigenum), and exhibit diverse physiological activities. In particular, AF is a promising drug candidate against African trypanosomiasis and a potential anticancer lead compound. These compounds are supposedly biosynthesized through farnesylation of orsellinic acid, but the details have not been established. In this study, we present all of the reactions and responsible genes for AF and AC biosyntheses inA. egyptiacum, identified by heterologou
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Helfrich, Eric J. N., Geng-Min Lin, Christopher A. Voigt, and Jon Clardy. "Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering." Beilstein Journal of Organic Chemistry 15 (November 29, 2019): 2889–906. http://dx.doi.org/10.3762/bjoc.15.283.

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Terpenoids are the largest and structurally most diverse class of natural products. They possess potent and specific biological activity in multiple assays and against diseases, including cancer and malaria as notable examples. Although the number of characterized terpenoid molecules is huge, our knowledge of how they are biosynthesized is limited, particularly when compared to the well-studied thiotemplate assembly lines. Bacteria have only recently been recognized as having the genetic potential to biosynthesize a large number of complex terpenoids, but our current ability to associate genet
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Liu, Yong-Cheng, Xiao-Xi Peng, Yan-Bing Lu, Xue-Xian Wu, Lin-Wu Chen, and Hong Feng. "Genome-wide association study reveals the genes associated with the leaf inclusion contents in Chinese medical tree Eucommia ulmoides." Bioscience, Biotechnology, and Biochemistry 85, no. 2 (2021): 233–41. http://dx.doi.org/10.1093/bbb/zbaa005.

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ABSTRACT Eucommia ulmoides is an economic tree that can biosynthesize secondary metabolites with pharmacological functions. Genetic basis of biosynthesis of these compounds is almost unknown. Therefore, genomic-wide association study was performed to exploit the genetic loci maybe involved in biosynthetic pathways of 5 leaf inclusions (aucubin, chlorogenic acid, gutta-percha, polyphenols, total flavonoids). It was shown that contents of the 5 leaf metabolites have a wide variation following normal distribution. A total of 2 013 102 single nucleotide polymorphism (SNP) markers were identified i
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Sato, Hajime, Masanobu Uchiyama, Kazuki Saito та Mami Yamazaki. "The Energetic Viability of Δ1-Piperideine Dimerization in Lysine-derived Alkaloid Biosynthesis". Metabolites 8, № 3 (2018): 48. http://dx.doi.org/10.3390/metabo8030048.

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Lys-derived alkaloids widely distributed in plant kingdom have received considerable attention and have been intensively studied; however, little is known about their biosynthetic mechanisms. In terms of the skeleton formation, for example, of quinolizidine alkaloid biosynthesis, only the very first two steps have been identified and the later steps remain unknown. In addition, there is no available information on the number of enzymes and reactions required for their skeletal construction. The involvement of the Δ 1 -piperideine dimerization has been proposed for some of the Lys-derived alkal
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Pan, Guohui, Zhengren Xu, Zhikai Guo, et al. "Discovery of the leinamycin family of natural products by mining actinobacterial genomes." Proceedings of the National Academy of Sciences 114, no. 52 (2017): E11131—E11140. http://dx.doi.org/10.1073/pnas.1716245115.

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Abstract (sommario):
Nature’s ability to generate diverse natural products from simple building blocks has inspired combinatorial biosynthesis. The knowledge-based approach to combinatorial biosynthesis has allowed the production of designer analogs by rational metabolic pathway engineering. While successful, structural alterations are limited, with designer analogs often produced in compromised titers. The discovery-based approach to combinatorial biosynthesis complements the knowledge-based approach by exploring the vast combinatorial biosynthesis repertoire found in Nature. Here we showcase the discovery-based
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Wu, Tong, Yumei Liu, Jinsheng Liu, Zhenya Chen, and Yi-Xin Huo. "Metabolic Engineering and Regulation of Diol Biosynthesis from Renewable Biomass in Escherichia coli." Biomolecules 12, no. 5 (2022): 715. http://dx.doi.org/10.3390/biom12050715.

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Abstract (sommario):
As bulk chemicals, diols have wide applications in many fields, such as clothing, biofuels, food, surfactant and cosmetics. The traditional chemical synthesis of diols consumes numerous non-renewable energy resources and leads to environmental pollution. Green biosynthesis has emerged as an alternative method to produce diols. Escherichia coli as an ideal microbial factory has been engineered to biosynthesize diols from carbon sources. Here, we comprehensively summarized the biosynthetic pathways of diols from renewable biomass in E. coli and discussed the metabolic-engineering strategies that
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Fujiwara, Kei, Taishi Tsubouchi, Tomohisa Kuzuyama, and Makoto Nishiyama. "Involvement of the arginine repressor in lysine biosynthesis of Thermus thermophilus." Microbiology 152, no. 12 (2006): 3585–94. http://dx.doi.org/10.1099/mic.0.29222-0.

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Abstract (sommario):
Lysine biosynthesis of Thermus thermophilus proceeds in a similar way to arginine biosynthesis, and some lysine biosynthetic enzymes from T. thermophilus so far investigated have the potential to function in arginine biosynthesis. These observations suggest that arginine might regulate the expression of genes for lysine biosynthesis. To test this hypothesis, the argR gene encoding the regulator of arginine biosynthesis was cloned from T. thermophilus and its function in lysine biosynthesis was analysed. The addition of arginine to the culture medium inhibited the growth of an arginase gene kno
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Tesi sul tema "Biosynthesis"

1

Eyles, Tom. "Biosynthetic Lego : reprogramming RiPP biosynthesis." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/69571/.

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Ribosomally synthesised and post translationally modified peptides (RiPPs) are a diverse class of industrially-important and clinically-relevant natural products. Reprogramming the biosynthesis of RiPPs can provide an understanding of their biosynthesis, increases in their yield, and compound derivatives. In this thesis, two RiPP biosynthetic pathways are reprogrammed to achieve these aims. Bottromycin is a potent antibiotic RiPP, however it is produced in low yields by its native producer and it is rapidly hydrolysed in blood plasma. It was hypothesised that the bottromycin gene cluster could
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Khairudin, Khairunisa. "Biosynthetic studies and combinatorial biosynthesis of pleuromutilin antibiotics." Thesis, University of Bristol, 2018. http://hdl.handle.net/1983/46271504-0b2b-457a-92d0-073885f512cd.

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Pleuromutilin has potential as a next-generation antibiotic, and many semi-synthetic pleuromutilin derivatives have been developed. Recently, characterization of individual enzymatic steps involved in the production of pleuromutilin has been carried out. A linear pathway of pleuromutilin biosynthesis was established; however, there is a possibility of alternative or shunt pathways. Thus, the first part of this thesis aimed to investigate if any other possible routes could lead to the biosynthesis of pleuromutilin. Two alternative pathways were identified from the expression of various combinat
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Walczak, Robbie J. "Analyses of antibiotic biosyntheses in Streptomyces spp. : the molecular biology of nonactin biosynthesis and the novel biochemistry of daunorubicin biosynthesis /." The Ohio State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488205318510564.

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Gray, Jennifer A. "Biotin biosynthetic enzymes and the metabolic control of biotin biosynthesis." [Ames, Iowa : Iowa State University], 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1473213.

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Jackson, Catherine Mary. "Tetronasin biosynthesis." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303274.

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Jacobs, Adam. "Aspyrone biosynthesis." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241064.

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Ndiege, Isaiah Omolo. "Polyketide biosynthesis." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315331.

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Suzuki, Shiro. "Stereochemical diversity in lignan biosynthesis and establishment of norlignan biosynthetic pathway." Kyoto University, 2002. http://hdl.handle.net/2433/78141.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第9652号<br>農博第1280号<br>新制||農||848(附属図書館)<br>学位論文||H14||N3684(農学部図書室)<br>UT51-2002-G410<br>京都大学大学院農学研究科応用生命科学専攻<br>(主査)教授 島田 幹夫, 教授 桒原 保正, 教授 坂田 完三<br>学位規則第4条第1項該当
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Purvis, Michael Bernard. "Stereochemical aspects of virginiamycin biosynthesis: biosynthesis of antibiotic A33853." Diss., Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/54266.

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Abstract (sommario):
The biochemical pathways for the formation of the unusual amino acids found in virginiamycin M₁ and A33853 were investigated. Specifically tritiated and carbon 14 labeled serines were incorporated into virginiamycin M₁. (2S)-serine and (2S,3R)-[3-³H] serine were found to be precursors, thus giving evidence of stereochemical control in the formation of the oxazole moiety. This information allowed for postulation of a ring closure pathway. Stereochemical investigations were also carried out on the dehydroproline unit and it was shown that both (R) and (S) prolines were incorporated into the dehy
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Milne, Keith Livingston. "Bacterial isoprenoid biosynthesis." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/11172.

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Abstract (sommario):
This thesis describes a possible alternative isoprenoid pathway in bacteria by considering some previously unpublished feeding studies in the context of the related background literature. Three synthetic routes to 2,4-dihydroxy-4-methyltetrahydropyran (63) and three synthetic strategies towards the synthesis of 2-carboxy-2,4-dihydroxy-4-methyltetrahydropyran (63) are discussed. These compounds are considered as potential intermediates in the proposed alternative bacterial isoprenoid pathway. Labelled synthesis of (63) and structural analysis of (63) and 4-hydroxy-2-methoxy-4-methyltetrahydropy
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Libri sul tema "Biosynthesis"

1

Leeper, Finian J., and John C. Vederas, eds. Biosynthesis. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/3-540-48146-x.

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Smith, C. A., and E. J. Wood. Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3.

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Bu'Lock, J. D., ed. Biosynthesis. Royal Society of Chemistry, 2007. http://dx.doi.org/10.1039/9781847555786.

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Leeper, Finian J., and John C. Vederas, eds. Biosynthesis. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/3-540-69542-7.

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A, Smith C., and Wood Edward J. 1941-, eds. Biosynthesis. Chapman and Hall, 1992.

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Arnstein, H. R. V. Protein biosynthesis. IRL Press at Oxford University Press, 1992.

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E, Esterhouse Toma, and Petrinos Lado B, eds. Protein biosynthesis. Nova Science, 2008.

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Diana, Patrizia, and Girolamo Cirrincione. Biosynthesis of Heterocycles. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118960554.

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M, Jordan P., ed. Biosynthesis of tetrapyrroles. Elsevier, 1991.

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Volova, T. G. Hydrogen-based biosynthesis. Nova Science Publishers, 2009.

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Capitoli di libri sul tema "Biosynthesis"

1

Smith, C. A., and E. J. Wood. "Basic principles of biosynthesis." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_1.

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Smith, C. A., and E. J. Wood. "Photosynthesis." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_2.

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Smith, C. A., and E. J. Wood. "Carbohydrates and gluconeogenesis." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_3.

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Smith, C. A., and E. J. Wood. "Polysaccharides." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_4.

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Smith, C. A., and E. J. Wood. "Nitrogen fixation and incorporation of nitrogen into amino acids." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_5.

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Smith, C. A., and E. J. Wood. "Amino acid interconversions." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_6.

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Smith, C. A., and E. J. Wood. "Purines and pyrimidines." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_7.

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Smith, C. A., and E. J. Wood. "Lipid biosynthesis." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_8.

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Smith, C. A., and E. J. Wood. "Polyisoprenoids and porphyrins." In Biosynthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2356-3_9.

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Simpson, Thomas J. "Application of Isotopic Methods to Secondary Metabolic Pathways." In Biosynthesis. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/3-540-69542-7_1.

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Atti di convegni sul tema "Biosynthesis"

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Asswad, R., W. Djema, O. Bernard, J. L. Gouzé, and E. Cinquemani. "Optimization of microalgae biosynthesis via controlled algal-bacterial symbiosis*." In 2024 IEEE 63rd Conference on Decision and Control (CDC). IEEE, 2024. https://doi.org/10.1109/cdc56724.2024.10886300.

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Karlo, Jiro, and Surya Pratap Singh. "Vibrational tag coupled Raman imaging for visualizing biosynthesis pathways in action." In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIII, edited by Attila Tarnok, Jessica P. Houston, and Xuantao Su. SPIE, 2025. https://doi.org/10.1117/12.3043501.

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Jurenka, Russell. "Pheromone biosynthesis in moths." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.111632.

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Rohova, Maryna, Vladyslav Kovalenko, Volodymyr Tkachenko, Inna Lych, and Iryna Voloshyna. "Green Biosynthesis of Zinc Nanoparticles." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.iv.12.

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Abstract (sommario):
Currently there is a growing need for the development of an environmentally friendly process of synthesis of nanoparticles, during which no toxic chemicals are used. That is why an important area of research in nanotechnology sphere is the synthesis of metal nanoparticles by microorganisms such as bacteria and yeast (detoxification often occurs by reduction of metal ions/formation of metal sulfides). Bacteria are the organism of choice due to their fast growth, high efficiency and low cost. Metal nanoparticles exhibit antimicrobial properties, but the properties of nanoparticles depend on thei
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Skrotska, Oksana, and Pavlo Holubiev. "The role of Saccharomyces genus and their metabolites in biosynthesis of nanoparticles." In VI International Conference on European Dimensions of Sustainablе Development. National University of Food Technologies, 2024. https://doi.org/10.24263/edsd-2024-6-37.

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Abstract (sommario):
Biological methods of nanoparticle synthesis are environmentally friendly, as well as simple, fast, and cost-effective. Among the various biological systems that can be used for the biosynthesis of nanoparticles, yeast of the genus Saccharomyces has several advantages, since these microorganisms and their metabolites are completely safe for humans, animals, and the environment. In addition, yeast synthesize a large number of biologically active compounds (proteins, enzymes, amino acids, organic acids, vitamins), which can participate in the biosynthesis and stabilization of nanoparticles. When
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Rumyantsev, S. D., S. V. Veselova, T. V. Nuzhnaya, and G. F. Burkhanova. "Role of the Stagonospora nodorum effector SnTox3 in regulation of cytokinins synthesis and metabolism in infected wheat plants." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.209.

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The effect of the Stagonospora nodorum effector SnTox3 on the biosynthesis and metabolism of cytokinins of host plant was studied. The SnTox3 effector influenced the biosynthesis of cytokinins along an ethylene-dependent and ethylene-independent pathway.
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Usmanov, I. Yu, A. V. Scherbakov, V. B. Ivanov, and E. R. Yumagulova. "Fractal analysis of flavonoid biosynthesis system." In IX Congress of society physiologists of plants of Russia "Plant physiology is the basis for creating plants of the future". Kazan University Press, 2019. http://dx.doi.org/10.26907/978-5-00130-204-9-2019-446.

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Nassar, S., B. Liu, and L. Beerhues. "Polyketide-related biosynthesis of plant anthranoids." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399796.

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Jing Guo, Ming Tien, and Jeffrey M Catchmark. "Biosynthesis of cellulose binding domains (CBDs)." In 2009 Reno, Nevada, June 21 - June 24, 2009. American Society of Agricultural and Biological Engineers, 2009. http://dx.doi.org/10.13031/2013.27275.

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Duperray, A., A. Troesch, R. Berthier, E. Chagnon, and G. Marguerie. "BIOSYNTHESIS AND ASSEMBLY OF PLATELET GPIIbIIIa." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643958.

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Abstract (sommario):
Platelet GPIIbIIIa is a calcium-dependent heterodimer which is constituted of two proteins subunits GPIIb and GPIIIa. The GPIIb is itself made of two disulfide-linked subunits IIba and IIbβ. GPIlia is a single chain protein. GPIIbIIIa serves as a receptor for fibrinogen, fibronectin and von Willebrand factor and is implicated in platelet adhesive reactions. This protein is a member of an adhesion receptor protein family for which the name “cytoadhesins” has been proposed. As a preliminary step in the study of the genetic diversity of the members of this family, we have analysed the biosynthesi
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Rapporti di organizzazioni sul tema "Biosynthesis"

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Kelly, Karen, and Rene Jacobs. Phospholipid Biosynthesis. AOCS, 2011. http://dx.doi.org/10.21748/lipidlibrary.39191.

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Parry, Ronald J. Investigations of Thaxtomin Biosynthesis. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada418760.

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Cramer, Randall J. Biosynthesis of Energetic Materials. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada419511.

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McCarthy, James B. Hyaluronan Biosynthesis in Prostate Cancer. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443676.

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McCarthy, James B. Hyaluronan Biosynthesis in Prostate Carcinoma. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427815.

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Lamb, C. J. Biosynthesis of plant plasmamembrane polypeptides. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/5688524.

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McCarthy, James B. Hyaluronan Biosynthesis in Prostate Carcinoma. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada415957.

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McCarthy, James B. Hyaluronan Biosynthesis in Prostate Carcinoma. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada470599.

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Hawkins, D. R. Triterpenoid biosynthesis in Euphorbia lathyris latex. Office of Scientific and Technical Information (OSTI), 1987. http://dx.doi.org/10.2172/5625757.

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Benning, Christoph. Regulation of Oil Biosynthesis in Algae. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada567212.

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