Bibliografie tematiche / Bones - growth. eng

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Letteratura scientifica selezionata sul tema "Bones - growth. eng"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 14 febbraio 2022

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Articoli di riviste sul tema "Bones - growth. eng"

Hagan, Michael. "Sticks and Bones." Arithmetic Teacher 33, no. 1 (1985): 44–45. http://dx.doi.org/10.5951/at.33.1.0044.

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The proliferation of both teacher-made and professionally prepared games might easily tempt a teacher to conclude that using them to kindle a child's interest in mathematics is an end in itself. And yet the full riches of many games may lie undiscovered until children are challenged to go beyond their interests, to think about their actions, and to elaborate on them. From this perspective, the most valuable games are those that interest children and that have rich variations to encourage their growth.

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Chagin, Andrei S., Elham Karimian, Katja Sundström, Emma Eriksson, and Lars Sävendahl. "Catch-up growth after dexamethasone withdrawal occurs in cultured postnatal rat metatarsal bones." Journal of Endocrinology 204, no. 1 (2009): 21–29. http://dx.doi.org/10.1677/joe-09-0307.

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Children exposed to systemic glucocorticoids often exhibit growth retardation and after the cessation of therapy catch-up growth occurs in many, but not all patients. The developmental regulation and underlying cellular mechanisms of catch-up growth are not fully understood. To clarify this issue, we established an in vitro model of catch-up growth. Here we present a protocol for the long-term culture (up to 160 days) of fetal (E20) as well as postnatal (P8) rat metatarsal bones which allowed us to characterize ex vivo the phenomenon of catch-up growth without any influence by systemic factors

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DiGiancamillo, Mauro, Giovanni Rattegni, Michela Podestà, Luigi Cagnolaro, Bruno Cozzi, and Leo Leonardi. "Postnatal ossification of the thoracic limb in striped dolphins (Stenella coeruleoalba) (Meyen, 1833) from the Mediterranean Sea." Canadian Journal of Zoology 76, no. 7 (1998): 1286–93. http://dx.doi.org/10.1139/z98-055.

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We analyzed the thoracic limbs of 24 striped dolphins, Stenella coeruleoalba, by means of X-ray techniques. The body length of the dolphins, the number of postnatal dentine growth layers in the teeth, the degree of ossification of the hyoid bones, and development of the gonads (when available) were correlated with X-rays and used to estimate growth stages and skeletal maturity. Newborn animals showed advanced ossification centers in the humerus and at the proximal end of the radius and ulna. The proximal end of the humerus and the distal end of the radius and ulna ossify later, followed by clo

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Mahgoub, O., and G. A. Lodge. "Growth and body composition of Omani local sheep 2. Growth and distribution of musculature and skeleton." Animal Science 58, no. 3 (1994): 373–79. http://dx.doi.org/10.1017/s0003356100007315.

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AbstractDistribution of tissue weight in the musculature and skeleton was studied in ram, wether and ewe Omani sheep raised under an intensive management system and slaughtered over the range 18 to 38 kg live weight. Ram lambs had higher muscle weight in the forequarters than wether and ewe lambs whereas the latter ‘sexes’ had heavier hindquarters and slightly more muscle in the muscle groups of proximal hind- and forelimbs and those surrounding the spinal column. Some of the neck region muscles, e.g. m. splenius and m. longissimus capitis et atlantis, were more developed in ram than in wether

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Gregg, John B., and Larry J. Zimmerman. "Malnutrition in Fourteenth-Century South Dakota: Osteopathological Manifestations." North American Archaeologist 7, no. 3 (1987): 191–214. http://dx.doi.org/10.2190/m698-gja3-um3p-qrc9.

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Analysis of mutilated skeletons representing people massacred at the fourteenth-century Crow Creek village on the Missouri River bluffs in central proto-South Dakota provided information implicating metabolic deficiencies as significant factors in the catastrophe. Prominent findings were: lines in long bones indicating metabolic stress during growth; superior orbital plate, skull surface, and long bone changes attributable to iron deficiency anemia; decreased bone cortex density and marrow space modifications suggesting the effect of anemia or malnutrition; surface markings near juvenile long

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Perelmuter, M. N. "A criterion for the growth of cracks with bonds in the end zone." Journal of Applied Mathematics and Mechanics 71, no. 1 (2007): 137–53. http://dx.doi.org/10.1016/j.jappmathmech.2007.03.002.

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Pennisi, Angela, Xin Li, Bart Barlogie, John Shaughnessy PhD, and Shmuel Yaccoby. "Consequences of Intermittent PTH Treatment on Myeloma Growth, Bone Disease and Molecular Profiling of Whole Myelomatous Bone." Blood 116, no. 21 (2010): 4063. http://dx.doi.org/10.1182/blood.v116.21.4063.4063.

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Abstract Abstract 4063 Intermittent PTH (iPTH) treatment is bone anabolic and has been successfully used for treatment of osteoporosis. The aims of the study were to investigate the effects of iPTH-induced bone formation on myeloma progression and unravel molecular mechanisms associated with these effects, using the SCID-rab and SCID-hu models. Using our reported procedure (Xin et al., BJH 2007), we established a novel myeloma cell line, Hg, capable of sequential passaging in experimental models. Hg cells have similar gene expression profiling (GEP) as the original patient's plasma cells, are

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Gupta, Anil Kumar, and M. N. Ambekar. "Study Of Nutrient Foramina In Adult Human Femur Bones." Journal of Nepalgunj Medical College 14, no. 2 (2018): 44–49. http://dx.doi.org/10.3126/jngmc.v14i2.21538.

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Background: The role of nutrient foramen (NF) in nutrition and growth of the bones is evident from term Nutrient itself. The nutrient foramen is opening of nutrient canal on the surface of shaft of the bone which conducts the nutrient artery and the peripheral nerves to bones. Long bones receive most of the interosseous blood supply (70% to 80%) from the nutrient arteries and remaning (20% to 30%) through the periosteal vessels. Nutrient arteries play an important role in nutrition and growth of the bones particularly during early phases of ossification and growth. The present study is of grea

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Seely, Daniel R., and George A. Gates. "Parosteal Osteogenic Sarcoma of the Mastoid Bone." Annals of Otology, Rhinology & Laryngology 106, no. 9 (1997): 729–32. http://dx.doi.org/10.1177/000348949710600902.

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Parosteal osteogenic sarcoma (POS) is an uncommon surface bone tumor, most often arising from the metaphyseal end of long bones. Involvement of the cranial bones is rare, with only 1 case of mastoid bone POS previously reported in the literature. Two patients with POS of the mastoid are presented, 1 followed up for 25 years after surgical treatment. The presenting signs and symptoms, as well as distinctive radiographic findings, are discussed. Histologic features are also described. Typically, cranial POS appears as a sessile, densely ossified surface growth with radiating bone spicules that b

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Huttenlocker, Adam K., and Jennifer Botha-Brink. "Body size and growth patterns in the therocephalianMoschorhinus kitchingi(Therapsida: Eutheriodontia) before and after the end-Permian extinction in South Africa." Paleobiology 39, no. 2 (2013): 253–77. http://dx.doi.org/10.1666/12020.

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The continuous fossil record of therocephalian therapsids (Eutheriodontia) across the Permo-Triassic boundary and their differential survivorship of the end-Permian extinction offer an exceptional deep-time perspective on vertebrate life-history evolution during episodes of large-scale ecological perturbation. To examine potential impacts of the extinction on body size evolution (e.g., “Lilliput” effects) and growth patterns, we investigated cranial sizes and limb bone histology in the therocephalianMoschorhinus kitchingiboth before and after the end-Permian extinction, facilitated by analysis

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Più fonti

Tesi sul tema "Bones - growth. eng"

Schwartz, Filho Humberto Osvaldo. "Osteogênese sobre titânio com nanotopografia /." Araraquara : [s.n.], 2011. http://hdl.handle.net/11449/110660.

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Orientador: Resemary Adriana Chierici Marcantonio Banca: Eduardo Hochuli Vieira Banca: José Eduardo Cezar Sampaio Banca: Fábio André dos santos Banca: Sergio Luis Scombatti de Souza Resumo: Os objetivos deste estudo foram avaliar a influência da nanotopografia de superfícies de titânio no processo de osteogênese por meio de avaliação histológica do contato osso-implante, em ratos, sob efeito da inalação forçada da fumaça de cigarro; Avaliar a osteogênese e a expressão de citocinas em cultura de células primárias sobre discos de titânio com nanotopografia; E avaliar o efeito morf

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Marcato, Simara Márcia. "Características do crescimento corporal, dos órgãos e tecidos de duas linhagens comerciais de frangos de corte /." Jaboticabal : [s.n.], 2007. http://hdl.handle.net/11449/104952.

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Orientador: Nilva Kazue Sakomura Banca: Elisabeth Gonzales Banca: Renato Luis Furlan Banca: Alice Eiko Murakami Banca: Francisco Ernesto Moreno Bernal Resumo: Com objetivo determinar os parâmetros de crescimento do peso vivo e da ave depenada, das penas e componentes químicos corporais, das partes, dos órgãos e tecidos de frangos de corte, machos e fêmeas das linhagens Ross e Cobb, foram utilizados 1920 pintos criados em galpão alojados em boxes. O delineamento foi inteiramente casualizado em esquema fatorial 2x2 (linhagens e sexo), 4 repetições de 120 aves cada. Foi avaliado o

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Martins, Marilia Compagnoni. "Utilização do plasma rico em plaquetas nos procedimentos cirúrgicos de elevação do seio maxilar : estudo histomorfométrico em humanos /." Araraquara : [s.n.], 2003. http://hdl.handle.net/11449/104765.

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Resumo: O propósito do presente estudo foi o de avaliar histomorfometricamente a neoformação óssea da região posterior de maxila após os procedimentos cirúrgicos de elevação de seio maxilar e enxerto ósseo autógeno inlay associado ou não ao Plasma Rico em Plaquetas, em dois períodos de tempo: 6 e 8 meses. Foram selecionados 20 pacientes, com idade média de 42 anos, em boas condições de saúde geral. Os pacientes foram divididos, aleatoriamente em três grupos sendo: Grupo 1: enxerto ósseo autógeno e biópsia da área 8 meses após a cirurgia, 4 pacientes (grupo controle). Grupo 2: enxerto ósseo aut

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Messora, Michel Reis. "Influência do plasma rico em plaquetas no reparo ósseo de defeitos de tamanho crítico em calvárias de ratos : estudo histológico e histométrico /." Araçatuba : [s.n.], 2005. http://hdl.handle.net/11449/96164.

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Orientador: Maria José Hitomi Nagata Banca: Maurício Guimarães Araújo Banca: Luiz Alberto Milanezi Resumo: Objetivo: O propósito deste estudo foi avaliar, histologicamente, a influência do Plasma Rico em Plaquetas (PRP) no reparo ósseo de defeitos de tamanho crítico (DTC) criados cirurgicamente em calvárias de ratos. Material e Método: 32 ratos foram divididos em 2 grupos: C (controle) e PRP (Plasma Rico em Plaquetas). Um DTC de 8 mm de diâmetro foi criado na calvária de cada animal. No Grupo C, o defeito foi preenchido somente com coágulo sangüíneo. No Grupo PRP, o defeito foi preenc

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Melo, Luiz Gustavo Nascimento de. "Influência da associação do plasma rico em plaquetas ao enxerto de osso autógeno no reparo ósseo de defeitos de tamanho crítico em calvárias de coelhos : estudo histológico e histométrico /." Araçatuba : [s.n.], 2007. http://hdl.handle.net/11449/104716.

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Orientador: Maria José Hitomi Nagata Banca: Mário Taba Junior Banca: Álvaro Francisco Bosco Banca: Ronaldo Célio Mariano Banca: Valdir Gouveia Garcia Resumo: O objetivo do presente trabalho foi avaliar, histologicamente, a influência da associação do plasma rico em plaquetas (PRP) ao enxerto de osso autógeno (OA) no reparo ósseo de defeitos de tamanho crítico (DTC) em calvárias de coelhos. Sessenta coelhos foram divididos em 3 grupos: C (controle), OA (osso autógeno) e OA/PRP (osso autógeno associado ao plasma rico em plaquetas). Um defeito de tamanho crítico, com 15 mm de diâme

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Stephen, Ashley Elizabeth. "The effects of intensive sports training on the growth plate and subsequent biomechanical development of long bones : a pilot study." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/870b6fb6-1204-4aeb-915d-973aea934344.

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Marcaccini, Andréa Márcia. "Avaliação do plasma rico em plaquetas no tratamento de defeitos ósseos e lesões periodontais de furca grau II. Estudos histológico e histomorfométrico em cães /." Araraquara : [s.n.], 2004. http://hdl.handle.net/11449/104747.

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Orientador: Elcio Marcantonio Junior Banca: Joni Augusto Cirelli Banca: Enilson Antonio Sallum Banca: Luis Carlos Spolidorio Banca: Paulo Tambasco de Oliveira Resumo: Os objetivos deste estudo foram avaliar o efeito de biomateriais associados ao PRP na formação óssea em defeitos padronizados de rádio e avaliar o efeito de PRP+RTG+enxerto ósseo autógeno para tratamento de lesões de furca grau II em cães. Para tal, em um primeiro estudo, foram confeccionados 5 defeitos de 5mm em cada rádio (direito e esquerdo) em 05 cães, constituindo assim espaços para preenchimento com os enxert

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Reddie, Lianne Catherine Rose. "A study of growth and development in the distal radius using the metaphyseal index." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/a-study-of-growth-and-development-in-the-distal-radius-using-the-metaphyseal-index(012d3c1d-8e2a-44ac-9b4f-dd3084e33714).html.

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Introduction: Metaphyseal inwaisting is a process that occurs during long bone growth and remodelling of epiphyses and results in a proportional increase in growth plate width (GPW) and a decrease in metaphyseal width (MW). The Metaphyseal Index (MI) compares GPW to MW, usually in the distal femur. However, due to bone-age assessments, the most commonly performed radiograph in children is that of the hand/forearm. Previous work showed that gymnasts have a more widened growth plate at the distal radius than normal children, but these studies did not quantify the morphological changes using the

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Soliman, Ashraf. "Study of growth and bone mineral density and factors affecting them in children and adolescents with thalassaemia major and sickle cell disease." Thesis, University of South Wales, 1998. https://pure.southwales.ac.uk/en/studentthesis/study-of-growth-and-bone-mineral-density-and-factors-affecting-them-in-children-and-adolescents-with-thalassaemia-major-and-sickle-cell-disease(9cd79851-b7a7-4df7-bb2d-65e71e48d6c4).html.

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Thalassaemia and sickle cell disease (SCD) are the most widely distributed blood genetic disorders that occur at a high frequency in some populations including the Mediterranean region, parts of the Middle East, South East Asia and the Indian subcontinent. It is estimated that thalassaemia major affects 100,000 newborn every year world-wide. The high incidence of these chronic haemolytic diseases in developing countries poses a high load on the national economy because of the expensive treatment protocols and the considerably high morbidity rates of these patients. Repeated blood transfusion t

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Edwards, Sarah. "Investigating the role of a novel ER molecular chaperone : Creld2 in the physiology and pathophysiology of endochondral bone growth." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/investigating-the-role-of-a-novel-er-molecular-chaperone-creld2-in-the-physiology-and-pathophysiology-of-endochondral-bone-growth(6fd49909-beec-42d1-a546-8b2411616e59).html.

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Cysteine rich with EGF-like domains 2 (Creld2) is a novel endoplasmic reticulum (ER) resident molecular chaperone that has been recently implicated in the ER stress signalling response (ERSS) and the unfolded protein response (UPR). Global transcriptomic data derived from in vivo mouse models of rare chondrodysplasias; Multiple Epiphyseal Dysplasia (MED Matn3 p.V194D) and Metaphyseal chondrodysplasia type Schmid (MCDS Col10a1 p.N617K), identified a significant upregulation in Creld2 expression in mutant chondrocytes. These chondrodysplasias share a common disease signature consisting of aberra

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Libri sul tema "Bones - growth. eng"

Skiba, Grzegorz. Fizjologiczne, żywieniowe i genetyczne uwarunkowania właściwości kości rosnących świń. The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 2020. http://dx.doi.org/10.22358/mono_gs_2020.

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Bones are multifunctional passive organs of movement that supports soft tissue and directly attached muscles. They also protect internal organs and are a reserve of calcium, phosphorus and magnesium. Each bone is covered with periosteum, and the adjacent bone surfaces are covered by articular cartilage. Histologically, the bone is an organ composed of many different tissues. The main component is bone tissue (cortical and spongy) composed of a set of bone cells and intercellular substance (mineral and organic), it also contains fat, hematopoietic (bone marrow) and cartilaginous tissue. Bones a

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Wordsworth, B. P. Skeletal dysplasias. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0150.

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Hughes, Jim. Orthopaedics. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198813170.003.0008.

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This chapter covers the basic approaches and techniques used in orthopaedic surgery, including the insertion and positioning of hardware and fixators, closed and open techniques (including manipulation under anaesthetic), and the typical imaging requirements for these. The discussion includes elective and trauma cases, as well as emergency procedures that may be performed out of regular working hours. They generally involve either repair to the skeleton and joints after injury (e.g. resiting a dislocated joint or aligning and supporting a fractured long bone) or alterations (such as fusion or

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Bone Morphogenetic Proteins: Biological Characteristics and Reconstructive Repair (Tissue Engineering Intelligence Unit). Landes Bioscience, 1996.

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Lindholm, T. Sam. Bone Morphogenetic Proteins: Biology, Biochemistry and Reconstructive Surgery (Tissue Engineering Intelligence Unit Series). Academic Press, 1996.

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Sam, Lindholm T., ed. Bone morphogenetic proteins: Biology, biochemistry and reconstructive surgery. Academic Press, 1996.

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Capitoli di libri sul tema "Bones - growth. eng"

Krstić, Radivoj V. "Bony Tissue. Indirect or Chondral Bone Formation. End of Longitudinal Growth and Articular Cartilage." In General Histology of the Mammal. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70420-8_103.

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He, Wenliang, Peng Li, and Guoyao Wu. "Amino Acid Nutrition and Metabolism in Chickens." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-54462-1_7.

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AbstractBoth poultry meat and eggs provide high-quality animal protein [containing sufficient amounts and proper ratios of amino acids (AAs)] for human consumption and, therefore, play an important role in the growth, development, and health of all individuals. Because there are growing concerns about the suboptimal efficiencies of poultry production and its impact on environmental sustainability, much attention has been paid to the formulation of low-protein diets and precision nutrition through the addition of low-cost crystalline AAs or alternative sources of animal-protein feedstuffs. This necessitates a better understanding of AA nutrition and metabolism in chickens. Although historic nutrition research has focused on nutritionally essential amino acids (EAAs) that are not synthesized or are inadequately synthesized in the body, increasing evidence shows that the traditionally classified nutritionally nonessential amino acids (NEAAs), such as glutamine and glutamate, have physiological and regulatory roles other than protein synthesis in chicken growth and egg production. In addition, like other avian species, chickens do not synthesize adequately glycine or proline (the most abundant AAs in the body but present in plant-source feedstuffs at low content) relative to their nutritional and physiological needs. Therefore, these two AAs must be sufficient in poultry diets. Animal proteins (including ruminant meat & bone meal and hydrolyzed feather meal) are abundant sources of both glycine and proline in chicken nutrition. Clearly, chickens (including broilers and laying hens) have dietary requirements for all proteinogenic AAs to achieve their maximum productivity and maintain optimum health particularly under adverse conditions such as heat stress and disease. This is a paradigm shift in poultry nutrition from the 70-year-old “ideal protein” concept that concerned only about EAAs to the focus of functional AAs that include both EAAs and NEAAs.

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Wordsworth, B. P. "Skeletal dysplasias." In Oxford Textbook of Rheumatology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0150_update_001.

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Bone is metabolically active throughout life and metabolic disturbances may have wide-ranging consequences that are not restricted to altering its mechanics. The study of some genetic bone diseases has already provided remarkable insights into the normal regulation of bone metabolism. Skeletal dysplasias are developmental disorders of the chondro-osseous tissues commonly resulting in short stature, which is often disproportionate. The underlying mutations are often in the structural genes encoding components of the matrix but may also involve growth factors or cell signalling. In contrast, the dysostoses tend to affect single bones or groups of bones, reflecting the transient nature of the many different signalling factors to which they are responsive during development. Abnormalities of bone density (high or low) may be due to primary deficiency of bone matrix synthesis (e.g. osteogenesis imperfecta and hypophosphatasia) but may also reflect an imbalance between bone formation and resorption. This may be caused by abnormalities of bone formation (e.g. hyperostosis/sclerosteosis and osteoporosis pseudoglioma syndrome) or bone resorption (e.g. classic osteopetrosis and fibrous dysplasia).

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Smithers, Andrew. "Implications for Growth." In Productivity and the Bonus Culture. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198836117.003.0016.

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Without policy measures to offset the negative impact of the bonus culture, investment, productivity, and growth are likely to remain depressed. Given the slow growth of the working age population, the UK’s trend growth rate will thus be 1 per cent and that of the US 0.87 per cent, unless productivity improves. An alternative method of estimating US trend growth from the value data for tangible capital stock provides a slightly better rate of 1.1 per cent per annum. The prospects for the UK and US are so poor that policy measures to stimulate growth are vital. All growth is the result of changes in either TFP or NTV, so one or other must improve to avoid stagnation. There is no way to improve the former, but changes in NTV can be brought about through a lower hurdle rate, which requires the damage from the bonus culture to end.

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Calvo, Guillermo. "Liquidity Crunch/Trap: Some Unconventional Output/Employment/Growth Implications1." In Macroeconomics in Times of Liquidity Crises. The MIT Press, 2016. http://dx.doi.org/10.7551/mitpress/9780262035415.003.0005.

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The chapter shows that a sudden and sufficiently large contraction of bonds' liquidity could generate a fall in output, liquidity trap and price deflation, suggesting that there is no contradiction between Liquidity Crunch and Liquidity Trap, in line with the discussion in Chapter 2. The discussion is based on a simple model in which there are two types of liquid assets: fiat money and liquid bonds (e.g., Asset-Backed securities) under flexible prices. Fiat money is the liquid asset of choice for households, while under normal conditions firms have a preference for bonds. The model is employed to discuss quantitative easing (QE) in exchange for 'toxic' assets, and to show that the loss of bond liquidity could give rise to secular stagnation.

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Quinn, Sarah L. "Off-Budget and Decentralized." In American Bonds. Princeton University Press, 2019. http://dx.doi.org/10.23943/princeton/9780691156750.003.0008.

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This chapter outlines the growth of credit programs from the Second World War through the postwar era. This period saw a surge in wartime credit, the end of the Reconstruction Finance Corporation (RFC), and the emergence of government support for venture capital and school loans. As postwar credit programs moved capital and pioneered new ways of lending, they shaped how and where U.S. companies lent money. They also helped lift a generation of white families and systematically exclude African Americans. Discriminatory and decentralized, off-budget and complex, the credit programs were a key component of America's peculiar developmental state. Indeed, credit programs are not aberrations in the system. They are a core aspect of how the system works.

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Edouard, Thomas, and Maïthé Tauber. "Syndromic growth disorders." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.7086.

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Short stature (SS) is defined as height less than the third percentile or below –2 standard deviation score (SDS) with reference to chronological age according to standard growth curves. Children are born small for gestational age (SGA) when their birth height and/or birth weight are below or equal to –2 SDS using standards such as Usher and McLean. In patients presenting with SS associated with abnormal physical features, malformations, or delayed development, a syndromic growth disorder should be considered. Whilst individually rare, there are many syndromes with short stature as a component—in the London Dysmorphology Database (Winter and Baraitser), there are 873 such syndromes, 175 of which are of prenatal onset. In these patients, malformations and/or sensorineural abnormalities should be systematically screened by complementary exams (skeletal X-rays, cardiac and abdominal ultrasound, complete eye and hearing evaluations). In some cases, these abnormalities could help in making the diagnosis (e.g. pulmonary stenosis suggestive of Noonan’s syndrome). Different chromosome disorders may present with SS. For this reason, chromosome studies, preferably high-resolution analysis, should be performed to search for chromosome abnormalities in these children. Specific gene analysis may be requested when a specific syndrome is suspected. In these syndromes, growth failure may be due to a wide variety of mechanisms, including growth hormone deficiency (GHD), growth hormone resistance (Laron syndrome, bone dysplasia) or in combination with nutritional issues with, in many, the underlying mechanisms still being unknown. A complete evaluation of growth hormone/IGF-1 axis is necessary in these children. There are many classifications of short stature, each with specific advantages and disadvantages. Indeed, syndromes with SS could be classified according to clinical presentation and in particular auxological and anthropometrical parameters (SS with normal prenatal growth, SS with intrauterine growth retardation, SS with obesity), or to pathophysiology (GHD or growth hormone insensitivity, bone disorders and idiopathic SS). Here, a classification based on clinical presentation is used. Those syndromes with SS that are most common and are often followed by paediatric endocrinologists namely Silver–Russell, Noonan’s, Turner’s and Prader–Willi syndromes will be reviewed, as well as some rarer syndromes.

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"Cancers of the musculoskeletal system." In Oxford Desk Reference: Oncology, edited by Thankamma Ajithkumar, Ann Barrett, Helen Hatcher, and Sarah Jefferies. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198745440.003.0011.

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Primary malignant tumours of bone are rare and comprise a large number of histological subtypes. The most common are osteosarcoma, Ewing’s family of tumours, and chondrosarcoma. Each of these has further subgroups which will be discussed in detail under their subheadings. The remaining subgroups are exceptionally rare and include the presentation of spindle cell sarcoma of bone, e.g. malignant fibrous histiocytoma (MFH), within the bone as a primary lesion. MFH of bone is treated as other primary bone tumours. Soft tissue sarcomas represent a rare collection of heterogeneous tumours characterized by malignant growth of mesenchymal tissue. Different subgroups can be divided by genetics, pathology, anatomical location, and clinical behaviour. Less than 1% of malignant tumours with an incidence of 30 per million per annum. Median age at presentation depends on histological subtype. For example, rhabdomyosarcomas are most common in children and adolescents, whereas leiomyosarcomas predominate over the age of 40. This chapter covers cancers of musculoskeletal system. Topics include bone tumours overview; osteosarcoma (metastatic, non-metastatic, and recurrent); Ewing’s sarcoma; rare bone tumours; soft tissue sarcomas (management of localized disease, and of locally advanced and metastatic disease); retroperitoneal sarcoma; gastrointestinal stromal tumours; and future directions.

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Beckingsale, Thomas, and Craig Gerrand. "Bone tumours." In Oxford Textbook of Rheumatology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0147.

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Bone tumours comprise a heterogeneous mix of post-traumatic, developmental, benign, and malignant lesions. They can be subclassified according to their histological matrix as bone-forming, cartilage-forming, or fibre-forming, although some do not produce a specific matrix. Perhaps the most important distinction is between malignant tumours, which have a predisposition to invasive and destructive local growth and distant metastasis, and benign tumours, which do not metastasize, although some can demonstrate locally aggressive behaviour. Both benign and malignant bone tumours can present with unexplained pain and swelling. Radiographic investigation is mandatory to exclude bony malignancy, avoid delay in diagnosis, and prevent incorrect treatment such as arthroscopy or steroid injection when there is an underlying tumour. The three most common malignant tumours of bone are osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. If radiography indicates that bone cancer is a possibility, an urgent referral should be made to a bone cancer multidisciplinary team. Wherever possible, patients should be entered into clinical trials. Some chemosensitive tumours (e.g. osteosarcoma or Ewing’s tumours) require a combined approach to treatment, classically with adjuvant (preoperative) chemotherapy, local therapy (usually surgery), then adjuvant chemotherapy.

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Bunker, Bruce C., and William H. Casey. "Stress Corrosion Cracking: Chemically Activated Nanomechanics." In The Aqueous Chemistry of Oxides. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780199384259.003.0024.

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Although dissolution reactions involving water can etch and decompose oxides, truly catastrophic failures of oxide structures usually involve fractures and mechanical failures. Geologists and geochemists have long recognized that water and ice both play key roles in promoting the fracture and crumbling of rock (see Chapter 17). Freezing and thawing create stresses that amplify the rate at which water attacks metal–oxygen bonds at the crack tip. The interplay between water and stressed oxides also leads to common failures in man-made objects, ranging from the growth of cracks from flaws in windshields to the rupture of optical fibers in communication systems. In this chapter, we outline how mechanical deformations change the reactivity of metal–oxygen bonds with respect to water and other chemicals, and how reactions on strained model compounds have been used to predict time to failure as a function of applied stress. The basic phenomenon of stress corrosion cracking is illustrated in Figure 16.1. Cracks can propagate through oxide materials at extremely fast rates, as anyone who has dropped a wine glass on the floor can attest. High-speed photography reveals that when glass shatters, cracks can spread at speeds of hundreds of meters per second, or half the speed of sound in the glass. At the other end of the spectrum, cracks in glass can grow from preexisting flaws so slowly that only a few chemical bonds are broken at the crack tip per hour. Because mechanical failures are associated with cracking, it is critical for design engineers to understand the factors that control crack growth rates for this enormous range of crack velocities (a factor of 1012). In addition, because it is difficult to measure crack velocities slower than 10−8 m/second, it is often necessary to make major extrapolations from measured data to predict the long-term reliability of glass and ceramic objects. Will an optical fiber under stress fail in 1 year or 10 years? Answering this question can require accurate extrapolations down to crack growth rates as low as 10−10 m/second.

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Atti di convegni sul tema "Bones - growth. eng"

Shanjani, Yaser, Naveen Chandrashekar, and Ehsan Toyserkani. "Prediction of Biomechanical Properties of Bone Implant Scaffolds." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-43001.

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This work is concerned with the 3D finite element modeling of porous implants in which the pore characteristics and distribution are taken into account. The analysis is conducted for scaffolds composed of various biocompatible materials such as Hydroxyapatite, PMMA, PEEK, Ti-6Al-4V, Silicon Nitride, Zirconia and Alumina. Furthermore, the potential of bone growth within the scaffolds is investigated using principal strain histograms of loaded scaffolds. The results show that the histogram of the principal strain resembles a top hat distribution while the porosity (void fraction) decreases. For

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Fitzwater, Daric, Andrew Rophie, Benjamin Schroeder, et al. "FEA Analysis of a Portable Knee Rehabilitation Device Using Mechanical Loading." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-89192.

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In this paper, a solid model has been created with CAD software and analyzed with FEA software to obtain the deformed geometry, stress distribution, modal frequencies, temperature distribution, and life expectancy of a knee loading device that will be used in a combined biomedical and mechanical engineering research initiative. The purpose of this device is to mechanically load the end of the long bone of the human leg, causing movement of the fluids within the bone that can stimulate increased growth of bone tissues. This could potentially be used to speed the healing process of bone fracture

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Nover, Adam B., Katherine C. Wood, Grace D. O’Connell, et al. "Characterization of Depth-Dependent Mechanical Properties in Bio-Titanium Hybrid Osteochondral Tissue Engineered Constructs." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80600.

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With cartilage autografts and allografts in short supply, tissue engineered osteochondral (OC) grafts offer an alternative [1]. These constructs are comprised of a chondrocyte-seeded hydrogel region and a porous, bone-like base. Our laboratory has shown growth of more robust osteochondral constructs on clinically-relevant metal substrates (eg. tantalum) as opposed to devitalized bone, and these constructs have been evaluated in vivo [1,2]. Due to the presence of the base, it is expected that transport of nutrients and chemical factors in OC constructs will differ from transport in chondral-onl

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Smith, Michael, Stefan Cronjaeger, Navid Ershad, Randy Nickle, and Matthias Peussner. "Pipeline Data Analytics: Enhanced Corrosion Growth Assessment Through Machine Learning." In 2018 12th International Pipeline Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/ipc2018-78364.

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Effective integrity management of a corroded pipeline requires a significant quantity of data. Common data sources include in-line inspection (ILI), process monitoring, or external surveys. The key challenge for an integrity engineer is to leverage the data to understand the level of corrosion activity along the pipeline route, and make optimal decisions on future repair, mitigation and monitoring. This practice of gaining business insights from historical datasets is often referred to as ‘data analytics’. In this paper, a single application of data analytics is investigated — that of improvin

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Zhao, Daguan, Mohan Yu, Logan Lawrence, Pier Paolo Claudio, James B. Day, and Roozbeh (Ross) Salary. "Investigation of the Influence of Consequential Design Parameters on the Mechanical Performance of Biodegradable Bone Scaffolds, Fabricated Using Pneumatic Micro-Extrusion Additive Manufacturing Process." In ASME 2020 15th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/msec2020-8512.

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Abstract Pneumatic micro-extrusion (PME) is a high-resolution direct-write additive manufacturing process, which has emerged as the process of choice for tissue engineering and biofabrication of a broad spectrum of organs and tissues (e.g., bone, aortic valve, blood vessels, human ear, and nose). Despite the advantages and host of biomedical applications engendered by the PME process — including, for example, (i) accommodation of a wide range of material viscosity (enabled via thermopneumatic material deposition), (ii) large build volume and standoff distance for tissue engineering, (iii) in s

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Kim, Minwook, Jason A. Burdick, and Robert L. Mauck. "Influence of Chondrocyte Zone on Co-Cultures With Mesenchymal Stem Cells in HA Hydrogels for Cartilage Tissue Engineering." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80859.

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Mesenchymal stem cells (MSCs) are an attractive cell type for cartilage tissue engineering in that they can undergo chondrogenesis in a variety of 3D contexts [1]. Focused efforts in MSC-based cartilage tissue engineering have recently culminated in the formation of biologic materials possessing biochemical and functional mechanical properties that match that of the native tissue [2]. These approaches generally involve the continuous or intermittent application of pro-chondrogenic growth factors during in vitro culture. For example, in one recent study, we showed robust construct maturation in

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Baer, Thomas, Ryan Frisbie, Michael Willey, and Jessica Goetz. "Development of a Simplified Ankle Distractor." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3438.

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The physical impairment caused by OA of a single lower extremity joint is comparable to that reported for major life-altering disorders such as end-stage kidney disease and heart failure. (Buckwalter, et al) [1] Ankle distraction arthroplasty has been shown to greatly decrease pain due to end-stage ankle arthritis. Unlike arthrodesis (fusion of the joint), distraction arthroplasty maintains the joint’s natural movement, and it is far less complicated than total joint replacement surgery. There is a considerable body of research supporting the idea that distraction of an end-stage arthritic joi

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Solin, Jussi, Jouni Alhainen, Tommi Seppänen, H. Ertugrul Karabaki, and Wolfgang Mayinger. "Cyclic, Monotonic and Fatigue Performance of Stabilized Stainless Steel in PWR Water and Research Laboratory." In ASME 2018 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/pvp2018-84935.

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Strain controlled LCF testing extended to 10 million cycles revealed an abrupt endurance limit enforced by secondary hardening. In elevated temperatures the ε-N curve is rotated and endurance limit is lowered, but not vanished. When very low strain rates are applied at 325°C in simulated PWR environment, fatigue life is reduced, but far less than predicted according to NUREG/CR-6909. It is possible, but not probable that the difference is due to different stainless grades studied. We assume that the test method plays a more important role. We have repeatedly demonstrated in different tests cam

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Schauer, Raymond H., Leah K. Richter, and Tom Henderson. "Renewable Energy Expansion: A Model for the New Generation of Facilities." In 19th Annual North American Waste-to-Energy Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/nawtec19-5428.

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Created in 1978, the Solid Waste Authority of Palm Beach County (Authority) has developed an “award winning” solid waste management system that includes franchised solid waste collections and the following facilities to service the residents and businesses in Palm Beach County, Florida: • North County Resource Recovery Facility (NCRRF); • Residential and Commercial Recovered Materials Processing Facility; • Five Transfer Stations; • Class I Landfill; • Class III Landfill; • Biosolids Pelletization Facility; • Ferrous Processing Facility; • Woody Waste Recycling Facility; • Composting Facility;

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Huang, Hao, Qian Jiang, Abhijit Dasgupta, Ehsan Mirbagheri, and Krishna Darbha. "Creep Response of Assemblies Bonded With Pressure Sensitive Adhesive (PSA)." In ASME 2018 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/ipack2018-8345.

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Creep response of joints bonded with single-layered pressure sensitive adhesives (PSAs) was investigated in this study. PSAs are becoming more and more popular in the electronic industry as bonding media because of their ease of design, fast accurate bonding, environmentally-friendly bonding and ease of reworking. Such adhesive bonds are expected to experience complex, sustained loading conditions in service; e.g. loading due to large mass components, shock, temperature, or alignment mismatch of substrates. Stress-strain behavior of PSA bonding assembly has been extensively studied through exp

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Rapporti di organizzazioni sul tema "Bones - growth. eng"

Asia Bond Monitor September 2021. Asian Development Bank, 2021. http://dx.doi.org/10.22617/spr210338-2.

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In the second quarter of 2021, rising COVID-19 cases have cast a shadow over emerging East Asia's growth outlook. Yet the region's financial conditions remain broadly stable amid accommodative monetary policy stances despite some weakening signs. Local currency (LCY) bond markets in emerging East Asia expanded to $21.1 trillion at the end of June, as governments tapped LCY bonds to support recovery measures and contain the negative impact of rising COVID-19 cases. The ASEAN+3 sustainable bond market expanded to $345.2 billion at the end of Q2 2021, accounting for nearly 19% of the global susta

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Monetary Policy Report - January 2021. Banco de la República de Colombia, 2021. http://dx.doi.org/10.32468/inf-pol-mont-eng.tr1.-2021.

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Macroeconomic Summary Overall inflation (1.61%) and core inflation (excluding food and regulated items) (1.11%) both declined beyond the technical staff’s expectations in the fourth quarter of 2020. Year-end 2021 forecasts for both indicators were revised downward to 2.3% and 2.1%, respectively. Market inflation expectations also fell over this period and suggested inflation below the 3% target through the end of this year, rising to the target in 2022. Downward pressure on inflation was more significant in the fourth quarter than previously projected, indicating weak demand. Annual decelerati

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