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Articoli di riviste sul tema "Bones – Molecular aspects"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 agosto 2024

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1

Safarova, S. S. "Pathogenetic aspects of bone metabolism in diabetes mellitus." Clinical Medicine (Russian Journal) 96, no. 8 (December 20, 2018): 707–12. http://dx.doi.org/10.18821/0023-2149-2018-96-8-707-712.

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Metabolic disorders caused by diabetes affect bone remodeling, alter the structure and reduce the strength of bone tissue, leading to the development of diabetic osteopathy. However, between diabetes mellitus (DM) type 1 and 2 there are noticeable differences in the effect on the bone structure, which is obviously due to the different cellular and molecular mechanisms of these processes. The density of bone tissue with DM typel decreases, which leads to an increase in the risk of fractures by 7 times. With DM type 2, bone mineral density is moderately elevated, which is expected to lead to a d

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2

Wang, Yen-Hsiang, Kuan-Chieh Lee, Wen-Chun Wei, Chung-Huang Wang, Hao-Jie Liu, Jia-Rong Hou, Tien-Chen Hsieh, et al. "Hybrid Vibration and UV Fluorescence Technology for Rapid Imaging and Guidance for Manual Removal of Fish Bones from Fish Floss." Sensors 22, no. 22 (November 20, 2022): 8978. http://dx.doi.org/10.3390/s22228978.

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The objective of the proposed human–machine cooperation (HMC) workstation is to both rapidly detect calcium-based fish bones in masses of minced fish floss and visually guide operators in approaching and removing the detected fish bones by hand based on the detection of fingernails or plastic-based gloves. Because vibration is a separation mechanism that can prevent absorption or scattering in thick fish floss for UV fluorescence detection, the design of the HMC workstation included a vibration unit together with an optical box and display screens. The system was tested with commonly used fish

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3

Maltsev, S. V., A. I. Safina та T. V. Mihajlova. "Гипофосфатемический рахит у детей — клинические и генетические аспекты, подходы к терапии". Practical medicine 19, № 1 (2021): 38–49. http://dx.doi.org/10.32000/2072-1757-2021-1-38-49.

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Hypophosphatemic rickets (phosphate-diabetes) is a group of diseases associated with a defect in the reabsorption of phosphates in the proximal tubules, manifested by phosphaturia, hypophosphatemia and rickets deformities of the skeleton bones. Phosphate-diabetes has different genetic variants that determine the nature and severity of clinical manifestations. X-linked dominant hypophosphatemic rickets occurs most often (in 50-90% of cases). For the diagnosis, along with clinical characteristics, an important role is assigned to the study of partial renal functions, with the determination of cl

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4

Kushchayev, Sergiy V., Yevgeniya S. Kushchayeva, Sri Harsha Tella, Tetiana Glushko, Karel Pacak, and Oleg M. Teytelboym. "Medullary Thyroid Carcinoma: An Update on Imaging." Journal of Thyroid Research 2019 (July 7, 2019): 1–17. http://dx.doi.org/10.1155/2019/1893047.

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Medullary thyroid carcinoma (MTC), arising from the parafollicular C cells of the thyroid, accounts for 1–2% of thyroid cancers. MTC is frequently aggressive and metastasizes to cervical and mediastinal lymph nodes, lungs, liver, and bones. Although a number of new imaging modalities for directing the management of oncologic patients evolved over the last two decades, the clinical application of these novel techniques is limited in MTC. In this article, we review the biology and molecular aspects of MTC as an important background for the use of current imaging modalities and approaches for thi

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5

Rice, Ritva, Aki Kallonen, Judith Cebra-Thomas, and Scott F. Gilbert. "Development of the turtle plastron, the order-defining skeletal structure." Proceedings of the National Academy of Sciences 113, no. 19 (April 25, 2016): 5317–22. http://dx.doi.org/10.1073/pnas.1600958113.

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The dorsal and ventral aspects of the turtle shell, the carapace and the plastron, are developmentally different entities. The carapace contains axial endochondral skeletal elements and exoskeletal dermal bones. The exoskeletal plastron is found in all extant and extinct species of crown turtles found to date and is synaptomorphic of the order Testudines. However, paleontological reconstructed transition forms lack a fully developed carapace and show a progression of bony elements ancestral to the plastron. To understand the evolutionary development of the plastron, it is essential to know how

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6

Krupa, Robert, Małgorzata Suchanecka, Andrzej Mrożek, and Katarzyna Siwek. "Features of the flexor retinaculum and its individual variation in carpal tunnel syndrome predisposition - a systematic review." Medical Journal of Cell Biology 10, no. 3 (September 1, 2022): 97–101. http://dx.doi.org/10.2478/acb-2022-0015.

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Abstract The flexor retinaculum is a structure located in the wrist, which spreads between the bones forming the carpal tunnel. Its task is to maintain the relative stabilization and protection of incorporated structures. It is also an attachment for the thenar muscles, causing biomechanical interactions in the wrist. Pathologies occurring in the carpal tunnel structures often cause pressure increase, leading to compression of the median nerve, causing carpal tunnel syndrome (CTS). This work aims to review literature knowledge and compile research outcomes in the PubMED and Google scholar data

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7

Abe, Shinichi, and Masahito Yamamoto. "Factors Involved in Morphogenesis in the Muscle–Tendon–Bone Complex." International Journal of Molecular Sciences 22, no. 12 (June 14, 2021): 6365. http://dx.doi.org/10.3390/ijms22126365.

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A decline in the body’s motor functions has been linked to decreased muscle mass and function in the oral cavity and throat; however, aging of the junctions of the muscles and bones has also been identified as an associated factor. Basic and clinical studies on the muscles, tendons and bones, each considered independently, have been published. In recent years, however, research has focused on muscle attachment as the muscle–tendon–bone complex from various perspectives, and there is a growing body of knowledge on SRY-box9 (Sox9) and Mohawk(Mkx), which has been identified as a common controllin

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8

Poryadin, G. V., A. N. Zakhvatov, and D. V. Samarina. "Pathogenetic mechanisms of postmenopausal osteoporosis formation and their relationship with cardiovascular pathology." Bulletin of Siberian Medicine 21, no. 1 (April 15, 2022): 144–51. http://dx.doi.org/10.20538/1682-0363-2022-1-144-151.

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Involutional hormonal processes characteristic of the postmenopause are accompanied by disorders that deteriorate the quality of life in the female population and lead to an increased risk of developing metabolic diseases of the bones and cardiovascular system. In modern medicine, it is extremely important to understand the pathogenesis of postmenopausal osteoporosis (PMO) in association with cardiovascular diseases, which are the main causes of mortality in the population.This review is devoted to determining the key aspects of the pathogenesis of PMO and identifying their relationships with

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9

Jentgen-Ceschino, Benjamin, Koen Stein, and Valentin Fischer. "Case study of radial fibrolamellar bone tissues in the outer cortex of basal sauropods." Philosophical Transactions of the Royal Society B: Biological Sciences 375, no. 1793 (January 13, 2020): 20190143. http://dx.doi.org/10.1098/rstb.2019.0143.

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The histology of sauropod long bones often appears uniform and conservative along their evolutionary tree. One of the main aspects of their bone histology is to exhibit a fibrolamellar complex in the cortex of their long bones. Here, we report another bone tissue, the radial fibrolamellar bone (RFB), in the outer cortex of the humeri of a young adult cf. Isanosaurus (Early to Late Jurassic, Thailand) and an adult Spinophorosaurus nigerensis (Early to Middle Jurassic, Niger) that do not exhibit any pathological feature on the bone surface. Its location within the cortex is unexpected, because R

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10

Richardson, Jo, Takanori Shono, Masataka Okabe, and Anthony Graham. "The presence of an embryonic opercular flap in amniotes." Proceedings of the Royal Society B: Biological Sciences 279, no. 1727 (June 2011): 224–29. http://dx.doi.org/10.1098/rspb.2011.0740.

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The operculum is a large flap consisting of several flat bones found on the side of the head of bony fish. During development, the opercular bones form within the second pharyngeal arch, which expands posteriorly and comes to cover the gill-bearing arches. With the evolution of the tetrapods and the assumption of a terrestrial lifestyle, it was believed that the operculum was lost. Here, we demonstrate that an embryonic operculum persists in amniotes and that its early development is homologous with that of teleosts. As in zebrafish, the second pharyngeal arch of the chick embryo grows disprop

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11

Gentile, Cristina, and Francesco Chiarelli. "Rickets in Children: An Update." Biomedicines 9, no. 7 (June 27, 2021): 738. http://dx.doi.org/10.3390/biomedicines9070738.

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Rickets refers to a deficient mineralization of the growth plate cartilage, predominantly affecting longer bones. Despite the fact that preventive measures are available, it is still a common disease worldwide; nutritional rickets, due to vitamin D deficiency or dietary calcium inadequate intake, remains the most common form. Medical history, physical examination, radiologic features and biochemical tests are essential for diagnosis. Although recent studies suggest hypophosphatemia as the leading alteration, rickets is classically divided into two categories: calcipenic rickets and phosphopeni

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12

Pons-Belda, Oscar D., Mª Agustina Alonso-Álvarez, Juan David González-Rodríguez, Laura Mantecón-Fernández, and Fernando Santos-Rodríguez. "Mineral Metabolism in Children: Interrelation between Vitamin D and FGF23." International Journal of Molecular Sciences 24, no. 7 (April 3, 2023): 6661. http://dx.doi.org/10.3390/ijms24076661.

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Fibroblast growth factor 23 (FGF23) was identified at the turn of the century as the long-sought circulating phosphatonin in human pathology. Since then, several clinical and experimental studies have investigated the metabolism of FGF23 and revealed its relevant pathogenic role in various diseases. Most of these studies have been performed in adult individuals. However, the mineral metabolism of the child is, to a large extent, different from that of the adult because, in addition to bone remodeling, the child undergoes a specific process of endochondral ossification responsible for adequate

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13

YANG, XIUPING, FENGJU SUN, LONGTAO WANG, CHUNQIU ZHANG, and XIZHENG ZHANG. "SOLUTE TRANSPORT IN ARTICULAR CARTILAGE UNDER ROLLING-COMPRESSION LOAD." Journal of Mechanics in Medicine and Biology 19, no. 06 (September 2019): 1950054. http://dx.doi.org/10.1142/s0219519419500544.

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Solute transport is one of the important aspects involved in maintaining the physiological activity of tissues. The mechanical environment drives nutrition in and waste out in articular cartilage due to its avascularity, which plays a key role in the biological activity of articular cartilage. The human knee joint motion is a complex interaction between different bones including relative rolling and/or sliding movements. Rolling-compression process is a typical physiological load in knee joint motion. To investigate solute transport behavior in articular cartilage under rolling-compression loa

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14

Iwaszczuk, Urszula, Justyna Niderla-Bielińska, and Aneta Ścieżyńska. "Kings and peasants from El-Zuma/El-Detti microregion in the Early Makurian period. Economic aspects of animal bones from funerary contexts." PLOS ONE 14, no. 2 (February 15, 2019): e0212423. http://dx.doi.org/10.1371/journal.pone.0212423.

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15

Bishop, Peter J., Scott A. Hocknull, Christofer J. Clemente, John R. Hutchinson, Andrew A. Farke, Belinda R. Beck, Rod S. Barrett, and David G. Lloyd. "Cancellous bone and theropod dinosaur locomotion. Part I—an examination of cancellous bone architecture in the hindlimb bones of theropods." PeerJ 6 (October 31, 2018): e5778. http://dx.doi.org/10.7717/peerj.5778.

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This paper is the first of a three-part series that investigates the architecture of cancellous (‘spongy’) bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian species. Cancellous bone is widely known to be highly sensitive to its mechanical environment, and has previously been used to infer locomotor biomechanics in extinct tetrapod vertebrates, especially primates. Despite great promise, cancellous bone architecture has remained little utilized for investigating locomotion in many other ext

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16

Asseln, Malte, Valentin Quack, Roman Michalik, Björn Rath, Frank Hildebrand, Filippo Migliorini, and Jörg Eschweiler. "Sex-Specific Size Analysis of Carpal Bones: Implications for Orthopedic Biomedical Device Design and Therapy Planning." Life 14, no. 1 (January 18, 2024): 140. http://dx.doi.org/10.3390/life14010140.

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Consideration of the individual carpal bone characteristics of the wrist plays a key role in well-functioning biomedical devices and successful surgical procedures. Although geometric differences and individual bone sizes have been analyzed in the literature, detailed morphologic descriptions and correlations covering the entire wrist reported in a clinical context are lacking. This study aimed to perform a comprehensive and automatic analysis of the wrist morphology using the freely available “Open Source Carpal Database” (OSCD). We quantified the size of each of the individual carpal bones a

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17

Ousalm, R., O. El Kadiri, D. Ait Antar, M. Derfaoui, A. El Omrani, and M. Khouchani. "Radiotherapy’s Indications and Limits in the Management of Bone Ewing's Sarcoma’s Children: About 22 Cases and Review of the Literature." Scholars Journal of Medical Case Reports 11, no. 06 (June 7, 2023): 1087–99. http://dx.doi.org/10.36347/sjmcr.2023.v11i06.012.

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To study the indications and limits of radiotherapy in the treatment of bone Ewing's sarcoma’s children, we conducted a retrospective study of 22 cases collected over a period of 10 years from January 2011 to December 2020. The study took into account various clinical, radiological, therapeutic and evolutionary aspects of this pathology. The average age of patients was 11 years, with gender equality. The diagnostic approach was identical, based on clinical, radiological and histological data. Therapeutic management was based on chemotherapy, with local treatment combining radiotherapy with or

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18

Kubicek, Jan, Filip Tomanec, Martin Cerny, Dominik Vilimek, Martina Kalova, and David Oczka. "Recent Trends, Technical Concepts and Components of Computer-Assisted Orthopedic Surgery Systems: A Comprehensive Review." Sensors 19, no. 23 (November 27, 2019): 5199. http://dx.doi.org/10.3390/s19235199.

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Computer-assisted orthopedic surgery (CAOS) systems have become one of the most important and challenging types of system in clinical orthopedics, as they enable precise treatment of musculoskeletal diseases, employing modern clinical navigation systems and surgical tools. This paper brings a comprehensive review of recent trends and possibilities of CAOS systems. There are three types of the surgical planning systems, including: systems based on the volumetric images (computer tomography (CT), magnetic resonance imaging (MRI) or ultrasound images), further systems utilize either 2D or 3D fluo

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19

Sánchez-Gómez, Rubén, Ricardo Becerro de Bengoa-Vallejo, Marta Elena Losa-Iglesias, César Calvo-Lobo, Carlos Romero-Morales, Eva María Martínez-Jiménez, Patricia Palomo-López, and Daniel López-López. "Heel Height as an Etiology of Hallux Abductus Valgus Development: An electromagnetic Static and Dynamic First Metatarsophalangeal Joint Study." Sensors 19, no. 6 (March 16, 2019): 1328. http://dx.doi.org/10.3390/s19061328.

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Background: Hallux abductus valgus (HAV) is a forefoot condition produced by extrinsic and intrinsic factors. Shoes with a high heel height and a typical narrow tip toe box can induce deviations in both the proximal phalanx of the hallux (PPH) and the first metatarsal (IMTT) bones. Nevertheless, the isolated role of heel height remains unclear in the development of HAV pathology. Objectives: The goal was to determine if the heel height increase of shoes without a narrow box toe could augment the PPH and IMTT deviation in frontal, sagittal, and transverse planes toward the first metatarsophalan

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20

Indra, Lara, David Errickson, Alexandria Young, and Sandra Lösch. "Uncovering Forensic Taphonomic Agents: Animal Scavenging in the European Context." Biology 11, no. 4 (April 15, 2022): 601. http://dx.doi.org/10.3390/biology11040601.

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Animal scavenging by vertebrates can significantly alter human bodies and their deposition site. For instance, vertebrate animals can cause postmortem modification to a body, alter perimortem trauma, influence decomposition rates, disarticulate and scatter body parts or evidence, and affect the identification of the deceased. Animal scavenging is a relatively common occurrence in forensic investigations. Even so, studies on the subject are scattered and rare, with most focussing on geographical areas outside of Europe. For that reason, we intend to collate the literature to provide an account

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21

Riga, Alessandro, Marco Boggioni, Andrea Papini, Costantino Buzi, Antonio Profico, Fabio Di Vincenzo, Damiano Marchi, Jacopo Moggi-Cecchi, and Giorgio Manzi. "In situ observations on the dentition and oral cavity of the Neanderthal skeleton from Altamura (Italy)." PLOS ONE 15, no. 12 (December 2, 2020): e0241713. http://dx.doi.org/10.1371/journal.pone.0241713.

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The Neanderthal specimen from Lamalunga Cave, near Altamura (Apulia, Italy), was discovered during a speleological survey in 1993. The specimen is one of the most complete fossil hominins in Europe and its state of preservation is exceptional, although it is stuck in calcareous concretions and the bones are mostly covered by calcite depositions. Nevertheless, it is possible to carry out some observations on craniodental features that have not previously been described. In this work, we present an account of the oral cavity, made possible by the use of a videoscope, which allowed us to reach so

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22

Bumann, Erin E., Portia Hahn Leat, Henry H. Wang, Brittany M. Hufft-Martinez, Wei Wang, and Pamela V. Tran. "Genetic Interaction of Thm2 and Thm1 Shapes Postnatal Craniofacial Bone." Journal of Developmental Biology 10, no. 2 (May 11, 2022): 17. http://dx.doi.org/10.3390/jdb10020017.

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Ciliopathies are genetic syndromes that link skeletal dysplasias to the dysfunction of primary cilia. Primary cilia are sensory organelles synthesized by intraflagellar transport (IFT)—A and B complexes, which traffic protein cargo along a microtubular core. We have reported that the deletion of the IFT-A gene, Thm2, together with a null allele of its paralog, Thm1, causes a small skeleton with a small mandible or micrognathia in juvenile mice. Using micro-computed tomography, here we quantify the craniofacial defects of Thm2−/−; Thm1aln/+ triple allele mutant mice. At postnatal day 14, triple

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23

Evers, Serjoscha W., Christian Foth, and Oliver W. M. Rauhut. "Notes on the cheek region of the Late Jurassic theropod dinosaur Allosaurus." PeerJ 8 (February 7, 2020): e8493. http://dx.doi.org/10.7717/peerj.8493.

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Allosaurus, from the Late Jurassic of North America and Europe, is a model taxon for Jurassic basal tetanuran theropod dinosaurs. It has achieved an almost iconic status due to its early discovery in the late, 19th century, and due to the abundance of material from the Morrison Formation of the western U.S.A., making Allosaurus one of the best-known theropod taxa. Despite this, various aspects of the cranial anatomy of Allosaurus are surprisingly poorly understood. Here, we discuss the osteology of the cheek region, comprised by the jugal, maxilla, and lacrimal. This region of the skull is of

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24

Brönnimann, David, Johannes Wimmer, Milena Müller-Kissing, Barbara Stopp, Hannele Rissanen, and Norbert Spichtig. "One man’s trash is another man’s treasure. Interdisciplinary examination of taphonomic aspects of ceramic sherds, animal bones and sediments from the La Tène period settlement at Basel-Gasfabrik." PLOS ONE 15, no. 7 (July 27, 2020): e0236272. http://dx.doi.org/10.1371/journal.pone.0236272.

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Ferea, Cătălina Roxana, Stejara Nicoleta Mihai, Gabriela Balan, Minerva Codruta Badescu, Dana Tutunaru, and Alin Laurențiu Tatu. "Sweet Syndrome Associated with Myelodysplastic Syndrome—A Review of a Multidisciplinary Approach." Life 13, no. 3 (March 16, 2023): 809. http://dx.doi.org/10.3390/life13030809.

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Sweet syndrome (SS) is a rare disease described as a febrile neutrophilic dermatosis with acute onset, the pathogenesis of which has not yet been elucidated. The syndrome is characterized by the sudden onset of erythematous infiltrated papules or plaques located on the upper body and is associated with fever, leukocytosis and neutrophilia. The lesions show a dense dermal infiltration with mature neutrophils. The condition is responsive to systemic steroids. The central nervous system, bones, muscles, eyes, ears, mouth, heart, lung, liver, kidneys, intestines, and spleen may be affected by SS a

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Hearn, Les, and Amanda C. de C. Williams. "Pain in dinosaurs: what is the evidence?" Philosophical Transactions of the Royal Society B: Biological Sciences 374, no. 1785 (September 23, 2019): 20190370. http://dx.doi.org/10.1098/rstb.2019.0370.

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How far back can we trace behaviour associated with pain? Behaviour is not preserved in the palaeontological record, so, for dinosaurs, we are restricted to what we can deduce from fossilized bones and tracks. This review is a thought experiment using circumstantial evidence from dinosaur fossils and from the behaviour of their extant relatives to describe probable responses of dinosaurs to serious injuries. Searches yielded 196 papers and chapters with: reports of healed serious injuries, and limping gait and injured feet in trackways; information about physiology and behaviour relevant to he

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Kwiatkowska, Angelika, Monika Drabik, Agata Lipko, Anna Grzeczkowicz, Radosław Stachowiak, Anna Marszalik, and Ludomira H. Granicka. "Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing." Membranes 12, no. 2 (February 13, 2022): 215. http://dx.doi.org/10.3390/membranes12020215.

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Wound management is the burning problem of modern medicine, significantly burdening developed countries’ healthcare systems. In recent years, it has become clear that the achievements of nanotechnology have introduced a new quality in wound healing. The application of nanomaterials in wound dressing significantly improves their properties and promotes the healing of injuries. Therefore, this review paper presents the subjectively selected nanomaterials used in wound dressings, including the metallic nanoparticles (NPs), and refers to the aspects of their application as antimicrobial factors. T

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Kara, Michał. "Groby o domniemanych skandynawskich atrybucjach etno-kulturowych z obszaru państwa pierwszych Piastów w kontekście archeologicznych paradygmatów badawczych." Slavia Antiqua. Rocznik poświęcony starożytnościom słowiańskim, no. 64 (December 13, 2023): 133–67. http://dx.doi.org/10.14746/sa.2023.64.5.

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In spite of the differences in the interpretation of early medieval graves of the discussed Norman or Ruthenian attribution, derivatives of different theoretical and cognitive paradigms, successive generations of researchers are united in their conviction of the exceptional nature of these graves in the Oder-Vistula interfluve. Archaeologists are also unanimous in treating them as burials from the 2nd half of the 10th to the 1st half of the 11th century which present a set of specific burial practices, distinguishing one of the groups of the secular elite of the first Piast state. However, res

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Baab, Karen L. "Reconstructing cranial evolution in an extinct hominin." Proceedings of the Royal Society B: Biological Sciences 288, no. 1943 (January 20, 2021): 20202604. http://dx.doi.org/10.1098/rspb.2020.2604.

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Homo erectus is the first hominin species with a truly cosmopolitan distribution and resembles recent humans in its broad spatial distribution. The microevolutionary events associated with dispersal and local adaptation may have produced similar population structure in both species. Understanding the evolutionary population dynamics of H. erectus has larger implications for the emergence of later Homo lineages in the Middle Pleistocene. Quantitative genetics models provide a means of interrogating aspects of long-standing H. erectus population history narratives. For the current study, cranial

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McCurry, Matthew R., Alistair R. Evans, Erich M. G. Fitzgerald, Justin W. Adams, Philip D. Clausen, and Colin R. McHenry. "The remarkable convergence of skull shape in crocodilians and toothed whales." Proceedings of the Royal Society B: Biological Sciences 284, no. 1850 (March 8, 2017): 20162348. http://dx.doi.org/10.1098/rspb.2016.2348.

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The striking resemblance of long-snouted aquatic mammals and reptiles has long been considered an example of morphological convergence, yet the true cause of this similarity remains untested. We addressed this deficit through three-dimensional morphometric analysis of the full diversity of crocodilian and toothed whale (Odontoceti) skull shapes. Our focus on biomechanically important aspects of shape allowed us to overcome difficulties involved in comparing mammals and reptiles, which have fundamental differences in the number and position of skull bones. We examined whether diet, habitat and

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Righini, Matteo, Raul Mancini, Marco Busutti, and Andrea Buscaroli. "Autosomal Dominant Polycystic Kidney Disease: Extrarenal Involvement." International Journal of Molecular Sciences 25, no. 5 (February 22, 2024): 2554. http://dx.doi.org/10.3390/ijms25052554.

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Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder, but kidneys are not the only organs involved in this systemic disorder. Individuals with the condition may display additional manifestations beyond the renal system, involving the liver, pancreas, and brain in the context of cystic manifestations, while involving the vascular system, gastrointestinal tract, bones, and cardiac valves in the context of non-cystic manifestations. Despite kidney involvement remaining the main feature of the disease, thanks to longer survival, early diagnosis, and be

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Jacobs, Megan L., and David M. Martill. "A new ophthalmosaurid ichthyosaur from the Upper Jurassic (Early Tithonian) Kimmeridge Clay of Dorset, UK, with implications for Late Jurassic ichthyosaur diversity." PLOS ONE 15, no. 12 (December 9, 2020): e0241700. http://dx.doi.org/10.1371/journal.pone.0241700.

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A new ophthalmosaurid ichthyosaur, Thalassodraco etchesi gen. et sp. nov., from the Upper Jurassic Kimmeridge Clay Formation of Dorset, UK is described. The specimen, a partial, articulated skull and anterior thorax in the Etches Collection of Kimmeridge, Dorset, is exceptionally well preserved on a slab of laminated coccolith limestone and has been expertly prepared. It comprises a near complete skull in articulation with associated anterior vertebral column and dorsal ribs, complete pectoral girdle, fully exposed left forelimb, and some elements of the right forelimb. Other elements present,

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Moen Taule, E., J. Brekke, H. Miletic, H. Sætran, S. Maric, I. HogenEsch, and R. Mahesparan. "P11.33.B A PATIENT WITH GLIOBLASTOMA AND EXTENSIVE EXTRANEURAL METASTASES - DOES MOLECULAR BIOLOGY PLAY A CRUCIAL ROLE?" Neuro-Oncology 25, Supplement_2 (September 1, 2023): ii80—ii81. http://dx.doi.org/10.1093/neuonc/noad137.267.

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Abstract BACKGROUND Extraneural metastases of glioblastoma (GBM) are rare, reported incidence in literature is 0.4% to 2%. There is a lack in epidemiological data, and what little exists is outdated. The most commonly reported sites of metastases are bone, lymph node and lung. There is an insufficient understanding of the biological mechanism of metastasis, nevertheless, surgical intervention and peritoneal seeding through a ventriculoperitoneal shunt have been postulated as rational routes for the tumor cells. However, reports show metastasizing GBM in patients where neither of these procedur

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Nargizyan, A., S. Kurbanova, A. Glazyrina, E. Korobyants, V. Yusupova, A. Sologub, and E. Zholobova. "AB1263 CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS IN CHILDREN: A SINGLE CENTER 10-YEAR EXPERIENCE." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1740.3–1741. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4976.

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BackgroundChronic recurrent multifocal osteomyelitis (CRMO) is a chronic autoinflammatory disease that primarily affects the skeleton in the absence of an infectious etiology in children and adolescents. It is an orphan disease with many unclear aspects in terms of diagnosis, treatment and follow-up.ObjectivesTo report demographic, clinical and laboratory characteristics of a single center cohort of CRMO patients in Morozovskaya Children’s City Clinical Hospital in Moscow, Russia.MethodsWe retrospectively and prospectively reviewed clinical records of 33 CRMO patients diagnosed between 2011 an

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Holland, Brayden, Phil R. Bell, Federico Fanti, Samantha M. Hamilton, Derek W. Larson, Robin Sissons, Corwin Sullivan, Matthew J. Vavrek, Yanyin Wang, and Nicolás E. Campione. "Taphonomy and taxonomy of a juvenile lambeosaurine (Ornithischia: Hadrosauridae) bonebed from the late Campanian Wapiti Formation of northwestern Alberta, Canada." PeerJ 9 (May 4, 2021): e11290. http://dx.doi.org/10.7717/peerj.11290.

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Hadrosaurid (duck-billed) dinosaur bonebeds are exceedingly prevalent in upper Cretaceous (Campanian–Maastrichtian) strata from the Midwest of North America (especially Alberta, Canada, and Montana, U.S.A) but are less frequently documented from more northern regions. The Wapiti Formation (Campanian–Maastrichtian) of northwestern Alberta is a largely untapped resource of terrestrial palaeontological information missing from southern Alberta due to the deposition of the marine Bearpaw Formation. In 2018, the Boreal Alberta Dinosaur Project rediscovered the Spring Creek Bonebed, which had been l

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Bishop, Peter J., Scott A. Hocknull, Christofer J. Clemente, John R. Hutchinson, Andrew A. Farke, Rod S. Barrett, and David G. Lloyd. "Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds." PeerJ 6 (October 31, 2018): e5777. http://dx.doi.org/10.7717/peerj.5777.

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This paper is the last of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian species. Cancellous bone is highly sensitive to its prevailing mechanical environment, and may therefore help further understanding of locomotor biomechanics in extinct tetrapod vertebrates such as dinosaurs. Here in Part III, the biomechanical modelling approach derived previously was applied to two species of extinct, non-avian theropods, Dasple

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Biz, Carlo, Rola Khamisy-Farah, Luca Puce, Lukasz Szarpak, Manlio Converti, Halil İbrahim Ceylan, Alberto Crimì, Nicola Luigi Bragazzi, and Pietro Ruggieri. "Investigating and Practicing Orthopedics at the Intersection of Sex and Gender: Understanding the Physiological Basis, Pathology, and Treatment Response of Orthopedic Conditions by Adopting a Gender Lens: A Narrative Overview." Biomedicines 12, no. 5 (April 29, 2024): 974. http://dx.doi.org/10.3390/biomedicines12050974.

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Abstract (sommario):

In the biomedical field, the differentiation between sex and gender is crucial for enhancing the understanding of human health and personalizing medical treatments, particularly within the domain of orthopedics. This distinction, often overlooked or misunderstood, is vital for dissecting and treating musculoskeletal conditions effectively. This review delves into the sex- and gender-specific physiology of bones, cartilage, ligaments, and tendons, highlighting how hormonal differences impact the musculoskeletal system’s structure and function, and exploring the physiopathology of orthopedic con

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Andrzejczuk-Hybel, J., K. Bartoszewicz, T. Bernacka, U. Dałek, A. Kusińska, W. Liss, and J. Kączkowski. "Some methodical aspects in investigations on wheat gluten." Acta Agrobotanica 25, no. 2 (2015): 161–70. http://dx.doi.org/10.5586/aa.1972.008.

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Abstract (sommario):

3 M urea has been shown to cause considerable, and only partially reversible conformational changes of gluten molecules. Homogenization has proved to act mechanically, breaking down some molecular bonds. No structural changes could be observed during freeze drying gluten, as well as after brief heating of its acetic acid extracts.

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Moore, Andrew J., Jinyou Mo, James M. Clark, and Xing Xu. "Cranial anatomy of Bellusaurus sui (Dinosauria: Eusauropoda) from the Middle-Late Jurassic Shishugou Formation of northwest China and a review of sauropod cranial ontogeny." PeerJ 6 (June 1, 2018): e4881. http://dx.doi.org/10.7717/peerj.4881.

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Abstract (sommario):

Bellusaurus sui is an enigmatic sauropod dinosaur from the Middle-Late Jurassic Shishugou Formation of northwest China. Bellusaurus is known from a monospecific bonebed preserving elements from more than a dozen juvenile individuals, including numerous bones of the skull, providing rare insight into the cranial anatomy of juvenile sauropods. Here, we present a comprehensive description of the cranial anatomy of Bellusaurus, supplementing the holotypic cranial material with additional elements recovered from recent joint Sino-American field expeditions. Bellusaurus is diagnosed by several uniqu

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Sugawara, André Tadeu, Milton Seigui Oshiro, Eduardo Inglez Yamanaka, Ronaldo Meneghetti, Dayrin Vanessa Tarazona Carvajal, Leandro Ryuchi Iuamoto, and Linamara Rizzo Battistella. "Half man, half prosthesis: the rehabilitation of people with hemicorporectomy – case series." F1000Research 10 (April 19, 2021): 298. http://dx.doi.org/10.12688/f1000research.51636.1.

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Hemicorporectomy is a procedure where the lumbar spine and spinal cord, pelvic bones and contents, lower extremities and external genitalia are surgically removed. The rehabilitation process, in addition to being prolonged and costly, is challenging. This article reports the rehabilitation process for hemicorporectomy and shows the innovative solutions for mobility for this disability for two cases of paraplegic patients: case 1 due to traumatic spinal cord injury due to firearm injury and case 2 due to lumbosacral myelomeningocele. They presented chronic pressure ulcer which evolved to neopla

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Clement, Alice M., Richard Cloutier, Jing Lu, Egon Perilli, Anton Maksimenko, and John Long. "A fresh look at Cladarosymblema narrienense, a tetrapodomorph fish (Sarcopterygii: Megalichthyidae) from the Carboniferous of Australia, illuminated via X-ray tomography." PeerJ 9 (December 10, 2021): e12597. http://dx.doi.org/10.7717/peerj.12597.

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Abstract (sommario):

Background The megalichthyids are one of several clades of extinct tetrapodomorph fish that lived throughout the Devonian–Permian periods. They are advanced “osteolepidid-grade” fishes that lived in freshwater swamp and lake environments, with some taxa growing to very large sizes. They bear cosmine-covered bones and a large premaxillary tusk that lies lingually to a row of small teeth. Diagnosis of the family remains controversial with various authors revising it several times in recent works. There are fewer than 10 genera known globally, and only one member definitively identified from Gond

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Butovskii, Mikhail V., and Rhett Kempe. "Rare earth–metal bonding in molecular compounds: recent advances, challenges, and perspectives." New Journal of Chemistry 39, no. 10 (2015): 7544–58. http://dx.doi.org/10.1039/c5nj00802f.

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Abstract (sommario):

In this review, all structurally authenticated molecular compounds with direct bonds between rare earth metals and transition or main group metals are summarized. Novel aspects of their syntheses, properties and reactivities are highlighted.

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Bhandary, Subhrajyoti, Rahul Shukla, and Kristof Van Hecke. "Effect of chemical substitution on the construction of boroxine-based supramolecular crystalline polymers featuring B←N dative bonds." CrystEngComm 24, no. 9 (2022): 1695–99. http://dx.doi.org/10.1039/d1ce01739j.

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Abstract (sommario):

B←N dative bond-associated molecular to polymeric crystals have been synthesized by tuning their electronic features. The supramolecular and quantum crystallographic aspects of the B←N dative bonds were thoroughly investigated.

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Yochelis, Shira, Eran Katzir, Yoav Kalcheim, Vitaly Gutkin, Oded Millo, and Yossi Paltiel. "Formation of Au-Silane Bonds." Journal of Nanotechnology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/903761.

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Abstract (sommario):

Many intriguing aspects of molecular electronics are attributed to organic-inorganic interactions, yet charge transfer through such junctions still requires fundamental study. Recently, there is a growing interest in anchoring groups, which considered dominating the charge transport. With this respect, we choose to investigate self-assembly of disilane molecules sandwiched between gold surface and gold nanoparticles. These assemblies are found to exhibit covalent bonds not only between the anchoring Si groups and the gold surfaces but also in plane crosslinks that increase the monolayer stabil

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Ueki, Takeshi, and Ryo Yoshida. "Recent aspects of self-oscillating polymeric materials: designing self-oscillating polymers coupled with supramolecular chemistry and ionic liquid science." Phys. Chem. Chem. Phys. 16, no. 22 (2014): 10388–97. http://dx.doi.org/10.1039/c4cp00980k.

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Abstract (sommario):

Herein, we summarise the recent developments in self-oscillating polymeric materials based on the concepts of supramolecular chemistry, where aggregates of molecular building blocks with non-covalent bonds evolve the temporal or spatiotemporal structure.

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STASYUK, I. V., and A. L. IVANKIV. "THERMODYNAMICS OF THE MOLECULAR COMPLEXES WITH CHAINS OF HYDROGEN BONDS." Modern Physics Letters B 06, no. 02 (January 20, 1992): 85–91. http://dx.doi.org/10.1142/s0217984992000119.

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Abstract (sommario):

A pseudo-spin reduced basis model for the description of the linear hydrogen-bonds molecular systems with strong correlations between protons on the neighbouring bonds is proposed. The proton states corresponding to the high-energy proton configurations near the heavy ionic groups are excluded from the initial basis. Some aspects of thermodynamics and energy spectrum for the proton subsystem of the molecular complexes are considered in the framework of reduced basis model. It is shown that for the complexes with large but finite number of hydrogen bonds N, the polarizability is proportional to

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Zappone, Bruno, George W. Greene, Emin Oroudjev, Gregory D. Jay, and Jacob N. Israelachvili. "Molecular Aspects of Boundary Lubrication by Human Lubricin: Effect of Disulfide Bonds and Enzymatic Digestion†." Langmuir 24, no. 4 (February 2008): 1495–508. http://dx.doi.org/10.1021/la702383n.

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Wu, Qian, Jingmai K. O’Connor, Shiying Wang, and Zhonghe Zhou. "Transformation of the pectoral girdle in pennaraptorans: critical steps in the formation of the modern avian shoulder joint." PeerJ 12 (February 29, 2024): e16960. http://dx.doi.org/10.7717/peerj.16960.

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Abstract (sommario):

Important transformations of the pectoral girdle are related to the appearance of flight capabilities in the Dinosauria. Previous studies on this topic focused mainly on paravians yet recent data suggests flight evolved in dinosaurs several times, including at least once among non-avialan paravians. Thus, to fully explore the evolution of flight-related avian shoulder girdle characteristics, it is necessary to compare morphology more broadly. Here, we present information from pennaraptoran specimens preserving pectoral girdle elements, including all purportedly volant taxa, and extensively com

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Anquetin, Jérémy, and Christian Püntener. "A new species of the large-headed coastal marine turtle Solnhofia (Testudinata, Thalassochelydia) from the Late Jurassic of NW Switzerland." PeerJ 8 (November 12, 2020): e9931. http://dx.doi.org/10.7717/peerj.9931.

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Abstract (sommario):

Background The large-headed turtle Solnhofia parsonsi is known by a handful of specimens from the Late Jurassic of Germany and Switzerland (maybe also France). Solnhofia parsonsi is traditionally regarded as a “eurysternid” Thalassochelydia, a group of small to medium sized, mostly lagoonal or marginal turtles found almost exclusively in the Late Jurassic of Europe. More recently, Solnhofia parsonsi has been proposed to be a close relative of Sandownidae, an enigmatic group of Cretaceous to Paleogene turtles characterized by a derived cranial anatomy and a wider geographical distribution. Sand

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Bandrivska, N. N., and Yu Yu Lysokon. "Epidemiology and Etiopathogenetic Factors of the Development of Aggressive Forms of Periodontitis." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 8, no. 1 (February 27, 2023): 8–13. http://dx.doi.org/10.26693/jmbs08.01.008.

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Abstract (sommario):

The purpose of the work was to study the etiology and main etiopathological factors of the development of aggressive forms of periodontitis based on the analysis of additional pathogenetic aspects of mineral metabolism disorders according to modern literature. Materials and methods. The bibliosemantic method was used to clarify the state of the problem, study the analysis of the results of previous scientific research based on literature sources and electronic resources. Results. Periodontitis is the most widespread disease among all periodontal pathologies (chronic generalized periodontitis o

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