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Letteratura scientifica selezionata sul tema "Breath cancer"

Autore: Grafiati

Pubblicato: 26 novembre 2022

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Articoli di riviste sul tema "Breath cancer"

Bukreyeva, Ye B., A. A. Bulanova e Yu V. Kistenev. "APPLYING OF GAS ANALYSIS IN DIAGNOSIS OF BRONCHOPULMONARY DISEASES". Bulletin of Siberian Medicine 13, n. 5 (28 ottobre 2014): 122–29. http://dx.doi.org/10.20538/1682-0363-2014-5-122-129.

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Bronchopulmonary system diseases are on the first place among the causes of people's death. Most of methods for lung diseases diagnosis are invasive or not suitable for children and patients with severe disease. One of the promising methods of clinical diagnosis and disease activity monitoring of bronchopulmonary system is analyzing of human breath. Directly exhaled breath or exhaled breath condensate are using for human breaths analyzing. Analysis of human breath can apply for diagnostic, long monitoring and evaluation of efficacy of the treatment bronchopulmonary diseases. Differential diagnostic between chronic obstructive lung disease (COPD) and bronchial asthma is complicated because they have differences in pathogenesis. Analysis of human breath allows to explore features of COPD and bronchial asthma and to improve differential diagnostic of these diseases. Human breaths analyzing can apply for diagnostic dangerous diseases, such as tuberculosis, lung cancer. The analysis of breath air by spectroscopy methods is new noninvasive way for diagnosis of bronchopulmonary diseases.

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Haick, Hossam, e Dina Hashoul. "Lung cancer breath tests". Expert Review of Respiratory Medicine 13, n. 7 (8 maggio 2019): 597–99. http://dx.doi.org/10.1080/17476348.2019.1614918.

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Polaka, Inese, Manohar Prasad Bhandari, Linda Mezmale, Linda Anarkulova, Viktors Veliks, Armands Sivins, Anna Marija Lescinska et al. "Modular Point-of-Care Breath Analyzer and Shape Taxonomy-Based Machine Learning for Gastric Cancer Detection". Diagnostics 12, n. 2 (14 febbraio 2022): 491. http://dx.doi.org/10.3390/diagnostics12020491.

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Background: Gastric cancer is one of the deadliest malignant diseases, and the non-invasive screening and diagnostics options for it are limited. In this article, we present a multi-modular device for breath analysis coupled with a machine learning approach for the detection of cancer-specific breath from the shapes of sensor response curves (taxonomies of clusters). Methods: We analyzed the breaths of 54 gastric cancer patients and 85 control group participants. The analysis was carried out using a breath analyzer with gold nanoparticle and metal oxide sensors. The response of the sensors was analyzed on the basis of the curve shapes and other features commonly used for comparison. These features were then used to train machine learning models using Naïve Bayes classifiers, Support Vector Machines and Random Forests. Results: The accuracy of the trained models reached 77.8% (sensitivity: up to 66.54%; specificity: up to 92.39%). The use of the proposed shape-based features improved the accuracy in most cases, especially the overall accuracy and sensitivity. Conclusions: The results show that this point-of-care breath analyzer and data analysis approach constitute a promising combination for the detection of gastric cancer-specific breath. The cluster taxonomy-based sensor reaction curve representation improved the results, and could be used in other similar applications.

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Abdah-Bortnyak, R. V., H. Haick, S. Billan, G. Peng, E. Trock, N. Shachada e A. Kuten. "Sniffing out cancer from real breath samples by means of nanomaterial-based electronic nose device". Journal of Clinical Oncology 27, n. 15_suppl (20 maggio 2009): e17552-e17552. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e17552.

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e17552 Background: Several studies have shown that characteristic patterns of volatile organic compounds (VOCs) appear to be elevated in the alveolar breath of cancer patients, as compared to healthy controls. It has been shown, that VOCs’ composition acts as a fingerprint for the distinction of a certain cancer from other cancers, including the cases where various cancers have similar type of biomarkers. The goal of the current study is to establish a background to ultimately achieve a simple-to-use device that can detect such patterns of cancer when exhaling into it. Methods: Breath samples were collected from 40 healthy volunteers and 75 patients having known conditions in six main categories: (I) 40 healthy controls; (II) 30 patients with lung cancer; (III) 15 patients with breast cancer; (IV) 20 patients with colon cancer; (V) 5 patients with prostate cancer; and (VI) 5 patients with head and neck cancer. The breath of the volunteers was examined by means of gas chromatography linked with mass spectrometry technique (GC-MS) as well as by an electronic nose device that is based on molecularly modified Au nanoparticles to check the feasibility of the electronic nose in cancer detection via breath samples Results: GC-MS results showed that each category of cancer has a unique pattern (or mixture) of VOCs. In parallel to these findings, results indicate the ability of nanomaterial-based electronic nose devices to differentiate between “healthy” and “cancerous” breath, and, furthermore, between the breath of patients with different cancer types, with >92% sensitivity. Conclusions: The electronic nose technology has a high potential for assessing various types of cancer via simple exhalation procedure. The results provide a launching pad towards obtaining an inexpensive, compact tool that is amenable to widespread screening and that has a potential for direct and real-time monitoring (2–3 minutes only). No significant financial relationships to disclose.

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Sivertsen, S. M., A. Bjørneklett, H. P. Gullestad e K. Nygaard. "Breath Methane and Colorectal Cancer". Scandinavian Journal of Gastroenterology 27, n. 1 (gennaio 1992): 25–28. http://dx.doi.org/10.3109/00365529209011161.

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Dobie, Monika. "Breath test to detect cancer". Nursing Standard 21, n. 46 (25 luglio 2007): 28. http://dx.doi.org/10.7748/ns.21.46.28.s34.

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Goodwin, Peter M. "Breath Test Detects Esophagogastric Cancer". Oncology Times 39, n. 5 (marzo 2017): 30. http://dx.doi.org/10.1097/01.cot.0000514193.74091.a7.

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Marshall, E. "A Breath Test for Cancer?" Science 259, n. 5100 (5 marzo 1993): 1395. http://dx.doi.org/10.1126/science.259.5100.1395.

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Uppal, N., e P. Singh. "Oral cancer: Breath of death". British Dental Journal 221, n. 5 (settembre 2016): 212. http://dx.doi.org/10.1038/sj.bdj.2016.619.

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Clarke, Berwyn. "Breath test aids cancer chemotherapy". Lancet Oncology 1 (maggio 2000): 6. http://dx.doi.org/10.1016/s1470-2045(09)70272-4.

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Tesi sul tema "Breath cancer"

Tran, Vanessa Hoang Medical Sciences Faculty of Medicine UNSW. "Breath biomarkers associated with lung cancer". Publisher:University of New South Wales. Medical Sciences, 2009. http://handle.unsw.edu.au/1959.4/43717.

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Lung cancer (LC) is often diagnosed at advanced stage and as a result, survival rates are low. Recent studies describe exhaled breath and exhaled breath condensate (EBC) as a potential non-invasive method of sampling the airways for assessing inflammation of the respiratory system, and possibly for the early detection of LC. It was hypothesised that higher concentrations of markers and protein will be present in the EBC of LC patients compared to those of normal controls and healthy smokers, and may aid in assessing lung status. Methods: The gaseous phase of breath was investigated for volatile organic compound (VOC) patterns using an electronic nose (eNose) system, in addition to off-line measurements of carbon monoxide (CO) and nitric oxide (NO) levels. The aqueous phase, EBC, was collected during tidal breathing through a glass collection device cooled to 4??C by ice. Nitrite/nitrate (NOx) and pH levels were determined by a fluorescent modification of the Griess method, and silicon chip sensor pH meter, respectively. Protein levels in EBC were examined with a bicinchoninic acid (BCA) assay, silver staining and PAGE techniques, while the levels of tumour markers, CYFRA 21-1 and CEA, were quantified by enzyme-linked immunosorbent assays (ELISA). Results: The eNose machine was not able to produce characteristic VOC profiles from exhaled breath unique to each study group, while no significant difference was observed for mean NOx concentrations in the LC group when compared to other subjects (p=0.8824). Higher protein levels were found in the EBC of LC patient compared to normal controls (p=0.0204), with subsequent measurements of elevated CEA levels observed in the LC group when compared to non-smokers and smokers (p=0.023). Conclusion: This study showed that protein can be detected in the exhaled breath condensate of patients, with a significantly elevated amount in the samples from newly diagnosed LC patients. The mechanism for these differences remains to be determined but may be related to inflammatory changes within the airway, such as vascular protein leakage and release of mediators. Future work may aim to identify the upregulated proteins, and focus on proteomics and tissue microarrays to explore candidate proteins.

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Thekedar, Bhushan. "Investigations on the use of breath gas analysis with Proton Transfer Reaction Mass Spectrometry (PTR-MS) for a non-invasive method of early lung cancer detection". kostenfrei, 2009. https://mediatum2.ub.tum.de/node?id=821780.

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Grabner, Enrico. "Untersuchung von Promotormethylierungen des p16-Gens im Atemkondensat von Patienten mit Bronchialkarzinom und Vergleich mit Tumorpräparaten". Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-158654.

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Angesichts der nach wie vor hohen Mortalität und Morbidität des Bronchialkarzinoms ist die Entwicklung geeigneter Methoden zur früheren Diagnostik eine wichtige Notwendigkeit, um die geringe durchschnittliche 5-Jahres-Überlebensrate von 15% – 18% zu steigern. Unter diesem Gesichtspunkt wurde in der vorliegenden Arbeit das Atemkondensat von Patienten mit Bronchialkarzinom als nicht-invasiv und kostengünstig zu gewinnendes Medium auf das Vorliegen eines potentiellen Screeningmarkers – dem methylierten Tumorsuppressor-Gen p16 – untersucht. Dazu wurde ein Versuchsablauf entwickelt, bei dem trotz des geringen DNA-Gehaltes im Atemkondensat p16-Methylierungen nachgewiesen werden konnten. Die letztendlich etablierte Methode war eine methylierungsspezifische nested-PCR mit anschließendem Restriktionsverdau durch das Restriktionsenzym BstUI. Des Weiteren erfolgte die Untersuchung von in Paraffin eingebetteten Tumorpräparaten der Patienten. In der anschließenden statistischen Auswertung wurde der Einfluss von verschiedenen Faktoren wie COPD-Grad, Tumorlage, Tumorart, Nikotinabusus und stattgehabte Chemo- oder Strahlentherapie auf den Methylierungsstatus des p16-Gens analysiert.

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Soerjomataram, Isabelle. "Multiple primary cancers in patients with breast ans skin cancer". [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10779.

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Habes, Chahrazed. "Stimulation du signal calcique et de la migration des cellules cancéreuses mammaires par le peptide LL-37 : un mécanisme d’attachement membranaire impliquant les glycosaminoglycanes et les syndécanes". Thesis, Tours, 2019. http://www.theses.fr/2019TOUR3807.

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Le peptide LL-37, peptide antimicrobien de l’immunité innée, est associé au développement tumoral. Sur des lignées cancéreuses mammaires. Il augmente le calcium intracellulaire et la migration. via l’activation de la voie PI3K/AKT et de canaux calciques. L’énantiomère (D)-LL-37 induit des effets similaires, excluant une interaction classique ligand-récepteur. Avec sa structure en hélice α amphipathique et sa charge nette +6, l’hypothèse était que le peptide utilise les charges négatives de glycanes sulfatés ou sialylés pour sa fixation membranaire avant d’induire ses activités. Des lectines végétales reconnaissant des structures glycaniques sialylées ou sulfatées inhibent la migration et le signal calcique induits par LL-37 mais l’implication de sialyltransférases n’a pas été démontrée. Des glycoaminoglycanes (GAGs) tels que les chondroïtine et héparine sulfatées, utilisés en tant que compétiteurs, ou une digestion enzymatique des GAGs (Chondroïtinase et héparinase) conduisent à une inhibition de 50 à 100% des activités migratoire et calcique induites par LL-37. L’inhibition de synthèse des GAGs par le Methylumbelliferyl β-D-xyloside ainsi qu’une diminution de la sulfatation par le chlorate de sodium confirment l’implication de ces glycanes sulfatés. Dans la perceptive d’identifier la ou les protéines glycosylées membranaires susceptibles de transduire les effets de LL-37, nous avons utilisé une approche ciblée en invalidant par siRNA la synthèse des protéines arborant des GAGs. Le syndécane 4 est impliqué dans les activités de LL-37. En conclusion, ces résultats soulignent l’implication de GAGs sulfatés portés par le syndécane 4 pour orienter la fixation de LL-37 à la membrane des cellules cancéreuses et médier ses activités pro-tumorales
Initially characterized by its antimicrobial activities, LL-37 has also been shown to significantly contribute to tumor development. On breast cancer cell lines, LL-37 increases intracellular calcium and their migration via the activation of PI3K/AKT signaling. Its all-D enantiomer (D)-LL-37 induces similar effects, which excludes an protein-protein interaction of LL-37 in a classic ligand-receptor manner. Its structure of an amphipathic a-helix with a net charge of +6 gave rise to the hypothesis that the peptide uses the negative charges of sulfoglycans or sialic acids to facilitate its attachment to the cell membrane and to induce its activities. Whereas several lectins, specifically attaching to sialylated or sulfated structures, blocked the activities of LL-37 on both calcium increase and cell migration, the suppression of several sialyltransferases had no effect. However, the competitive use of glycoaminoglycans (GAG) and chrondroitin and sulfated heparin, or treatment of the cell surface with chondroitinase and heparinase resulted in an activity loss of 50-100%. Similar results were obtained by confirmed by blocking the synthesis of GAGs with Methylumbelliferyl β-D-xyloside, and by suppression of glycan sulfurylation by sodium chlorate. Using a candidate approach by suppressing proteoglycan synthesis by RNA interference, syndecan 4 was shown to be involved in the activities of LL-37. This leads to the conclusion that sulfated GAGs linked to syndecans 4 guides the association of LL-37 to the membrane of cancer cells, thus being a mediator of its activities

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Irobi, Edward Okezie. "Time to Diagnosis of Second Primary Cancers among Patients with Breast Cancer". ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2661.

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Many breast cancer diagnoses and second cancers are associated with BRCA gene mutations. Early detection of cancer is necessary to improve health outcomes, particularly with second cancers. Little is known about the influence of risk factors on time to diagnosis of second primary cancers after diagnosis with BRCA-related breast cancer. The purpose of this cohort study was to examine the risk of diagnosis of second primary cancers among women diagnosed with breast cancer after adjusting for BRCA status, age, and ethnicity. The study was guided by the empirical evidence supporting the mechanism of action in the mutation of BRCA leading to the development of cancer. Composite endpoint was used to define second primary cancer occurrences, and Kaplan-Meier survival curves were used to compare the median time-to-event among comparison groups and BRCA gene mutation status. Cox proportional hazards was used to examine the relationships between age at diagnosis, ethnicity, BRCA gene mutation status, and diagnosis of a second primary cancer. The overall median time to event for diagnosis of second primary cancers was 14 years. The hazard ratios for BRCA2 = 1.47, 95% CI [1.03 - 2.11], White = 1.511, 95% CI [1.18 - 1.94], and American Indian/Hawaiian = 1.424, 95% CI [1.12 -1.81] showing positive significant associations between BRCA2 mutation status and risk of diagnosis of second primary colorectal, endometrial, cervical, kidney, thyroid, and bladder cancers. Data on risk factors for development of second cancers would allow for identification of appropriate and timely screening procedures, determining the best course of action for prevention and treatment, and improving quality of life among breast cancer survivors.

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Vehmanen, Paula. "Breast cancer-predisposing genes in Finnish breast and ovarian cancer families". Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/mat/bioti/vk/vehmanen/.

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Clark, Jacqueline. "Living with Breast Cancer: Emotion-Work Strategies in Breast Cancer Support Groups". NCSU, 2007. http://www.lib.ncsu.edu/theses/available/etd-03122007-104945/.

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Research on stress and coping has attempted to explain how people deal with difficult life events, such as the diagnosis of a potentially life-threatening disease. Little attention, however, has been given to how people work together to cope with and manage the emotions evoked by such events. The present study looks at women who joined four breast cancer support groups to help them cope with the emotional fallout of the disease. Data from participant observation in these four groups, in addition to 35 in-depth interviews, are used to develop an analysis of how the women learned to cope collectively with their disease. Seven emotion-work strategies are identified and discussed, including: (a) seeking information; (b) concealing illness; (c) engaging in sexualized joking; (d) practicing compensatory femininity; (e) creating and sharing medicalized stories; (f) taking on the identity of breast cancer survivor; and (g) redefining illness as a blessing. The analysis shows how these strategies were influenced by the class-based resources the women brought with them to the groups. It also illustrates how these strategies (and thus the women?s coping efforts) were influenced and constrained by the mainstream breast cancer culture.

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Pelon, Floriane. "Fibroblastic heterogeneity and metastatic spread in breast cancers Fibroblast heterogeneity drives metastatic spread in breast cancer through distinct mechanisms". Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2392&f=17330.

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Les cancers du sein, premiers cancers féminins et causes aujourd’hui encore de nombreux décès, sont classés en 3 sous-types moléculaires : luminaux –les plus répandus, HER2 et triple-négatifs (TN) –les plus agressifs. Lors du diagnostic, l’envahissement des ganglions lymphatiques axillaires par les cellules tumorales est établi. Il s’agit, en plus de la classification moléculaire, d’un marqueur pronostique utilisé en clinique pour stratifier les patientes, car il informe sur le risque de développement ultérieur de métastases, cause majeure des décès à l’heure actuelle. Les tumeurs solides, et notamment les cancers du sein, sont des écosystèmes complexes comprenant de nombreux types cellulaires qui interagissent avec les cellules cancéreuses. Parmi eux, les fibroblastes associés au cancer (CAF) sont les plus abondants et participent activement à de nombreux aspects de la tumorigenèse dont la croissance, l’invasion, l’angiogenèse, l’immunosuppression. Cependant, ils constituent une population hétérogène et à ce jour, très peu d’études ont analysé cette hétérogénéité tout en la liant aux diverses fonctions décrites des CAF. Dans ce projet, nous nous sommes intéressés au rôle de cette hétérogénéité fibroblastique dans la dissémination métastatique des cancers du sein. En combinant l’étude de plusieurs marqueurs de CAF, nous avons montré que les ganglions lymphatiques envahis par les cellules tumorales sont constitués de 4 sous-populations de CAF (CAF-S1, S2, S3 et S4), similaires à celles identifiées dans les tumeurs primaires appariées. De façon intéressante, ce sont les deux sous-types de CAF myofibroblastiques (αSMA+), CAF-S1 et particulièrement CAF-S4, qui s’accumulent préférentiellement dans les ganglions métastatiques. Ils présentent les mêmes signatures transcriptomiques entre les deux localisations tissulaires (ganglions envahis et tumeurs primaires correspondantes). Or, ces deux populations CAF-S1 et CAF-S4 augmentent le phénotype invasif des cellules tumorales, en régulant des fonctions complémentaires. D’un côté, les CAF-S1 sont hautement motiles, et stimulent la prolifération, la migration, l’invasion et l’initiation d’une transition épithélio-mésenchymateuse des cellules de cancer du sein. De l’autre, les CAF-S4 sont très contractiles, capables de remodeler la matrice extracellulaire et promeuvent ainsi l’invasion et la motilité des cellules tumorales dans des systèmes en 3 dimensions. Des expériences fonctionnelles suggèrent que l’action des CAF-S1 implique CXCL12 et TGFβ tandis que celle des CAF-S4 dépend de la voie NOTCH. En accord avec ces résultats, l’accumulation des CAF et leur identité dans les ganglions envahis constituent deux nouveaux facteurs pronostics dans les cancers du sein, indépendants du sous-type de cancers du sein et de l’envahissement ganglionnaire. En effet, un fort contenu en CAF-S4 y est associé avec un développement ultérieur de métastases à longue distance. Ainsi, analyser le contenu fibroblastique des ganglions axillaires au diagnostic pourrait constituer une information nouvelle et utile à la prise en charge des patientes
Breast cancers are the most common cancers in women and despite great improvements in treatments, they are still responsible for many deaths worldwide. They are classified into 3 main molecular subtypes: Luminal cancers are the most frequent ones, while HER2 and TN are the most aggressive. At diagnostic, lymph node involvement is also assessed as it constitutes, in addition to molecular classification, a strong prognostic marker. Indeed, it informs on the risk to develop further distant metastases, which is the main cause of death by cancer. Solid tumors, including breast cancers, are complex ecologies comprising numerous different cell types that interact with cancer cells. Among them, cancer-associated-fibroblasts (CAF) are the most abundant and actively participate in many tumor hallmarks such as tumor growth, invasion, immunosuppression and angiogenesis. However, they do not constitute a homogeneous population but so far, only few studies have characterized this heterogeneity and linked it to CAF previously described functions. In this project, we focused on the potential involvement of CAF heterogeneity in breast cancer metastatic spread. Combining the analysis of several CAF markers, we showed that invaded LN comprise 4 CAF subsets (CAF-S1, S2, S3 and S4), similar to those found in primary tumors. Interestingly, the two myofibroblastic subsets (αSMA+) CAF-S1 and especially CAF-S4 preferentially accumulate in metastatic LN and present the same transcriptomic profiles in both tumors and LN. Importantly, both CAF-S1 and CAF-S4 display pro-invasive properties, by acting at different levels on tumor cells. On the one hand, highly motile CAF-S1 stimulate breast cancer cell proliferation, migration and EMT initiation. On the other hand, CAF-S4 exhibit an important contractility and by remodeling the matrix they are able to promote tumor cell invasion in 3D. Functional studies highlight a CXCL12/TGFβ involvement in CAF-S1 functions while CAF-S4 pro-invasive phenotype appears to be Notch-dependent. In agreement with these data, we found that CAF accumulation and subset enrichment in involved LN were two new prognostic factors, independent of breast cancer molecular subtypes and LN status at diagnosis. Indeed, stromal rich LN with a predominance of CAF-S4 are associated with long distance metastases development and poor overall survival. Thus, we propose that analyzing LN fibroblastic content at diagnosis could constitute new and useful information to breast cancer patients’ care

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Cheok, Frida. "Participation in mammographic screenings in South Australia /". Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phc51843.pdf.

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Libri sul tema "Breath cancer"

Parks, Peggy J. Breat cancer. San Diego, CA: ReferencePoint Press, Inc., 2014.

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A, Johnson Judith. Breast cancer. [Washington, D.C.]: Congressional Research Service, Library of Congress, 1993.

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A, Johnson Judith. Breast cancer. [Washington, D.C.]: Congressional Research Service, Library of Congress, 1992.

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Breast cancer. Farmington Hills, Mich: Greenhaven Press, a part of Gale, Cengage Learning, 2016.

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Michell, Michael. Breast cancer. Cambridge: Cambridge University Press, 2010.

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Christobel, Saunders, e Meredith Sheena, a cura di. Breast cancer. Oxford: Oxford University Press, 1994.

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Baum, Michael. Breast cancer. 3^a ed. Oxford: Health Press, 2005.

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Kelly, Alison P. Breast cancer. Washington, D.C: Science Reference Section, Science, Technology and Business Division, Library of Congress, 2002.

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Vaidya, Jayant S. Breast cancer. Oxford: Health Press, 2010.

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Hardman, Lizabeth. Breast cancer. Detroit: Lucent Books, 2010.

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Capitoli di libri sul tema "Breath cancer"

Bergom, Carmen, Adam Currey, An Tai e Jonathan B. Strauss. "Deep Inspiration Breath Hold". In Radiation Therapy Techniques and Treatment Planning for Breast Cancer, 79–97. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40392-2_6.

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Conroy, L., R. Yeung, S. Quirk, T. Phan e W. L. Smith. "Retrospective evaluation of visually monitored deep inspiration breath hold for breast cancer patients using edge detection". In IFMBE Proceedings, 583–86. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19387-8_143.

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Al Alwan, Nada A. S. "General Oncology Care in Iraq". In Cancer in the Arab World, 63–82. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7945-2_5.

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AbstractThe estimated population of Iraq (40,222,493 in 2020) continues to grow at a rate of 2.4% per year; only 5% is over 60 years with a life expectancy approaching 72 years. There are 18 governorates in Iraq. Before 1990, Iraq had the most robust healthcare system in the Middle East. The consequences of the successive wars and political instability yielded a significant shortage in the medical resources and funds. Currently, the government spends 6–7% of its Gross Domestic Product (GDP) on the health sector, providing free of charge services to all citizens through a network of primary healthcare centers and public hospitals. The Iraqi Cancer Board of the Ministry of Health is responsible for implementing the National Cancer Control Plan (NCCP). The latest Iraqi Cancer Registry revealed that the top recorded malignancies among the population are the breast, bronchus, and lungs followed by colorectal cancers, whereas the most common causes of malignant related deaths are cancers of the bronchus and lungs, breast, and leukemia. Overall, there are over 40 public cancer care facilities distributed among the governorates. This chapter illustrates the general oncology care in Iraq; highlighting the implemented elements of the NCCP, the offered specialized cancer services, and the international collaborations on cancer control and research.

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Bawazir, Amen, Huda Basaleem, Ahmed Badheeb e Gamal Abdul Hamid. "General Oncology Care in the Republic of Yemen". In Cancer in the Arab World, 321–38. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7945-2_20.

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AbstractCancer is recognized nowadays as one of the important diseases in Yemen from the public health view. During the last three decades, remarkable changes in oncology health care services were observed in the country, mostly in urban areas. According to the Global Cancer Observatory of the International Agency for Research on Cancer, the total cases reported in the year 2020 was 16,476 new cases, and the top five reported cancers in the country were: breast cancer, colorectum, leukemia, stomach, and non-Hodgkin lymphomas. This rank of cancer types is probably unlike what exists in the neighboring Gulf countries. Oncology services in the country suffer from very limited radiotherapy care, chemotherapy centers, as well as many essential diagnostic laboratories for cancer.

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Lora-Wainwright, Anna. "Cancer and Contending Forms of Morality". In Fighting for Breath, 17–50. University of Hawai'i Press, 2013. http://dx.doi.org/10.21313/hawaii/9780824836825.003.0002.

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Lora-Wainwright, Anna. "Xiguan, Consumption, and Shifting Cancer Etiologies". In Fighting for Breath, 144–74. University of Hawai'i Press, 2013. http://dx.doi.org/10.21313/hawaii/9780824836825.003.0006.

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Crucitti, P. F., Filippo Longo, Raffaele Rocco e Gaetano Rocco. "e-Nose Technology: The State of the Art on Lung Cancer Diagnosis". In Breath Analysis, 121–29. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-814562-3.00007-2.

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"Chapter 1: Cancer and Contending Forms of Morality". In Fighting for Breath, 17–50. University of Hawaii Press, 2017. http://dx.doi.org/10.1515/9780824837976-004.

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"Chapter 5: Xiguan, Consumption, and Shifting Cancer Etiologies". In Fighting for Breath, 144–76. University of Hawaii Press, 2017. http://dx.doi.org/10.1515/9780824837976-008.

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Lora-Wainwright, Anna. "Performing Closeness, Negotiating Family Relations, and the Cost of Cancer". In Fighting for Breath, 177–99. University of Hawai'i Press, 2013. http://dx.doi.org/10.21313/hawaii/9780824836825.003.0007.

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Atti di convegni sul tema "Breath cancer"

Polaka, Inese, Marta Padilla, Linda Mezmale, Jan Mitrovics e Marcis Leja. "Class Decomposition for Gastric Cancer Detection from Breath". In 2021 62nd International Scientific Conference on Information Technology and Management Science of Riga Technical University (ITMS). IEEE, 2021. http://dx.doi.org/10.1109/itms52826.2021.9615341.

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Woodfield, Georgia, Ilaria Belluomo, Ivan Laponogov, Kirill Veselkov, Patrik Spanel, Amanda J. Cross e George B. Hanna. "OFR-7 Breath testing for colorectal polyps and cancer- the colorectal breath analysis1 study (COBRA1)". In Abstracts of the BSG Annual Meeting, 8–12 November 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-bsg.30.

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Lee, Sang-Seok. "Breath analysis based on micropreconcentrator for early cancer diagnosis". In Microfluidics, BioMEMS, and Medical Microsystems XVI, a cura di Bonnie L. Gray e Holger Becker. SPIE, 2018. http://dx.doi.org/10.1117/12.2302380.

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Alfeeli, Bassam, e Masoud Agah. "Micro preconcentrator for handheld diagnostics of cancer biomarkers in breath". In 2010 Ninth IEEE Sensors Conference (SENSORS 2010). IEEE, 2010. http://dx.doi.org/10.1109/icsens.2010.5690098.

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Maiti, K. S., E. Fill, F. Strittmatter, Y. Volz, R. Sroka e A. Apolonski. "Accurate diagnosis of prostate cancer via infrared spectroscopy of breath". In Translational Biophotonics: Diagnostics and Therapeutics, a cura di Lothar D. Lilge e Zhiwei Huang. SPIE, 2021. http://dx.doi.org/10.1117/12.2614582.

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Yu, Jin, Di Wang, Le Wang, Ping Wang, Yanjie Hu, Kejing Ying, Matteo Pardo e Giorgio Sberveglieri. "Detection of Lung Cancer with Volatile Organic Biomarkers in Exhaled Breath and Lung Cancer Cells". In OLFACTION AND ELECTRONIC NOSE: Proceedings of the 13th International Symposium on Olfaction and Electronic Nose. AIP, 2009. http://dx.doi.org/10.1063/1.3156506.

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Flexman, Molly L., Michael A. Khalil, Rabah M. Al Abdi, Beatriu Reig, Christopher J. Fong, Dawn Hershman, Elise Desperito, Randall L. Barbour e Andreas H. Hielscher. "Optical tomographic imaging of the hemodynamic response to a breath hold in breast cancer patients". In SPIE BiOS, a cura di Bruce J. Tromberg, Arjun G. Yodh, Mamoru Tamura, Eva M. Sevick-Muraca e Robert R. Alfano. SPIE, 2011. http://dx.doi.org/10.1117/12.875461.

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Daniel, D. Arul Pon, K. Thangavel e K. T. Rajakeerthana. "Empirical study on early detection of lung cancer using breath analysis". In 2015 International Conference on Innovations in Information,Embedded and Communication Systems (ICIIECS). IEEE, 2015. http://dx.doi.org/10.1109/iciiecs.2015.7192869.

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Spivack, Simon D., Miao Shi, Weiguo Han e Steven Keller. "Exhaled Breath MicroRNAs As Non-Invasive Biomarkers Of Lung Cancer Risk". In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2652.

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Ding, Siqi, Tianlin Hu, Yang Shen, Chun Lin e Yuanqing Huang. "Detection of Lung Cancer with Breath Biomarkers Based on SVM Regression". In 2009 Fifth International Conference on Natural Computation. IEEE, 2009. http://dx.doi.org/10.1109/icnc.2009.557.

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Rapporti di organizzazioni sul tema "Breath cancer"

Miller, George P. An Exploratory Study of Cavity Ringdown Spectroscopy as a Noninvasive Breath Diagnostic for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, marzo 2006. http://dx.doi.org/10.21236/ada465211.

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Wang, Ying yuan, Zechang Chen, Luxin Zhang, Shuangyi Chen, Zhuomiao Ye, Tingting Xu e Yingying Zhang c. A systematic review and network meta-analysis: Role of SNPs in predicting breast carcinoma risk. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, febbraio 2022. http://dx.doi.org/10.37766/inplasy2022.2.0092.

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Review question / Objective: P: Breast cancer patient; I: Single nucleotide polymorphisms associated with breast cancer risk; C: Healthy person; O: By comparing the proportion of SNP mutations in the tumor group and the control group, the effect of BREAST cancer risk-related SNP was investigated; S: Case-control study. Condition being studied: Breast cancer (BC) is one of the most common cancers among women, and its morbidity and mortality have continued to increase worldwide in recent years, reflecting the strong invasiveness and metastasis characteristics of this cancer. BC is a complex disease that involves a sequence of genetic, epigenetic, and phenotypic changes. Polymorphisms of genes involved in multiple biological pathways have been identified as potential risks of BC. These genetic polymorphisms further lead to differences in disease susceptibility and severity among individuals. The development of accurate molecular diagnoses and biological indicators of prognosis are crucial for individualized and precise treatment of BC patients.

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Bruno, Francesco, Domenico Arcuri, Francesca Vozzo, Antonio Malvaso, Alberto Montensanto e Raffaele Maletta. Expression and signaling pathways of Nerve Growth Factor (NGF) and pro-NGF in breast cancer: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, ottobre 2022. http://dx.doi.org/10.37766/inplasy2022.10.0017.

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Review question / Objective: This study aims to systematically review and comprehensively summarize the current experimental evidence about the involvement of Nerve Growth Factor (NGF) and pro-NGF signaling pathways in breast cancer. Therefore, the questions are as follows: (1) What is the expression level of NGF, pro-NGF and their receptors in breast cancer? (2) What is the role played by NGF, pro-NGF and their receptors in the pathophysiological mechanisms (i.e., proliferation, apoptosis, angiogenesis, invasion, metastasis) of breast cancer? (3) What is the diagnostic, prognostic and therapeutic potential of NGF, pro-NGF and their receptors in breast cancer? Condition being studied: Breast cancer is a neoplasm of epithelial origin that generally develops in the parts of the breast tissue made up of the glands involved in milk production or in the ducts that connect the glands to the nipple. In women it represents the most frequent cancer as well as the leading cause of cancer death. The incidence of breast cancer is estimated to increase over the years and to reach 3.2 million in 2050, thus representing a health emergency both from a medical and a psychological point of view. Therefore, prevention and early diagnosis of breast cancer appears to be of primary urgency as well as the development of new treatments able to improve its prognosis.

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Tangka, Florence K. L., Sujha Subramanian, Madeleine Jones, Patrick Edwards, Sonja Hoover, Tim Flanigan, Jenya Kaganova et al. Young Breast Cancer Survivors: Employment Experience and Financial Well-Being. RTI Press, luglio 2020. http://dx.doi.org/10.3768/rtipress.2020.rr.0041.2007.

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The economic burden of breast cancer for women under 50 in the United States remains largely unexplored, in part because young women make up a small proportion of breast cancer cases overall. To address this knowledge gap, we conducted a web-based survey to compare data from breast cancer survivors 18–39 years of age at first diagnosis and 40–49 years of age at first diagnosis. We administered a survey to a national convenience sample of 416 women who were 18–49 years of age at the time of their breast cancer diagnosis. We analyzed factors associated with financial decline using multivariate regression. Survivors 18–39 years of age at first diagnosis were more likely to report Stage II–IV breast cancer (P<0.01). They also quit their jobs more often (14.6%) than older survivors (4.4%; P<0.01) and faced more job performance issues (55.7% and 42.8%, respectively; P=0.02). For respondents in both groups, financial decline was more likely if the survivor had at least one comorbid condition (odds ratios: 2.36–3.21) or was diagnosed at Stage II–IV breast cancer (odds ratios: 2.04–3.51).

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Yelena, Gorina, e Elgaddal Nazik. Patterns of Mammography, Pap Smear, and Colorectal Cancer Screening Services Among Women Aged 45 and Over. National Center for Health Statistics, giugno 2021. http://dx.doi.org/10.15620/cdc:105533.

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This study examines and compares sociodemographic, health status, and health behavior patterns of screening for breast cancer, cervical cancer, and colorectal cancer among women aged 45 and over in the United States.

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Zhao, YiHao, e Dongbin Zhang. Efficacy and safety of trastuzumab combined with neoadjuvant chemotherapy in Chinese patients with HER-2 positive breast cancer: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, ottobre 2022. http://dx.doi.org/10.37766/inplasy2022.10.0003.

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Review question / Objective: To systematically evaluate the efficacy and safety of docetaxel combined with carboplatin and trastuzumab (TCH) neoadjuvant chemotherapy in Chinese patients with HER2-positive breast cancer. Condition being studied: Chinese patients who have been clinically diagnosed as HER-2 positive breast cancer, not complicated with basic diseases such as heart, liver and bone marrow, and who have received established surgery after chemotherapy and cooperated with follow-up. Eligibility criteria: Non-randomized controlled trials, animal experiments, literature review, non-docetaxel combined with carboplatin and trastuzumab as adjuvant therapy in Chinese breast cancer patients, and other drugs used in the intervention group or control group.

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Lin, Yawei, Yi Chen, Rongrong Liu e Baohua Cao. Effect of exercise on rehabilitation of breast cancer surgery patients: A systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, ottobre 2022. http://dx.doi.org/10.37766/inplasy2022.10.0065.

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Review question / Objective: Exercise after breast cancer surgery has proved beneficial to rehabilitation. We evaluate the best exercise for different post-surgery complications. Information sources: China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP China Science and Technology Journal Database, China Biology Medicine, EMBASE and PubMed databases were searched. Combinations of breast cancer (“breast tumor”,“breast carcinoma”,“mammary carcinoma”,“breast neoplasm”) and rehabilitation exercise (“exercise”,“physical therapy”) were employed when screening abstracts/keywords of articles. Two researchers independently searched, read the title and abstract of the literature, read the full text of the preliminary included literature, and extracted the data. In case of divergence, a third researcher was consulted.

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Wang, Yan, Wenpeng Song, Sicheng Zhou, Jie Tian, Yingxian Dong, Jue Li, Junke Chang et al. Increased risk for subsequent primary lung cancer among female hormone-related cancer patients: a meta-analysis based on over four million cases. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, luglio 2022. http://dx.doi.org/10.37766/inplasy2022.7.0044.

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Review question / Objective: To identify the risk of lung cancer in FHRC patients compared to the general population. Condition being studied: The incidence rate of lung cancer in women is obviously increasing over the past decade and previous evidence have indicated the significant relationship between disturbances in hormone levels and the risk of lung cancer. Therefore, we hypothesized female hormone-related cancer (FHRC), including the breast, endometrial, cervix, and ovary cancer, patients may experience a higher risk of developing subsequent lung cancer.

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Workman, Sarah, e Maddy Thompson. Breaking down barriers: Empowering Black women in breast cancer care. Royal Geographical Society (with IBG), marzo 2022. http://dx.doi.org/10.55203/vvdj9112.

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Joaquim, Ana, Inês Leão, Pedro Antunes, Andreia Capela, Sofia Viamonte, Alberto Alves, Luísa Helguero e Ana Macedo. Impact of physical exercise programs in breast cancer survivors on health-related quality of life, physical fitness, and body composition: evidence from systematic reviews and meta-analyses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, novembre 2022. http://dx.doi.org/10.37766/inplasy2022.11.0053.

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Review question / Objective: In breast cancer survivors, what is the effect of physical exercise interventions compared to control on health-related quality of life, physical fitness, and body composition? Condition being studied: Breast cancer. Eligibility criteria: Inclusion criteria: full-length articles in English with clinical observations of humans, with a clearly defined clinical question, details of inclusion and exclusion criteria, details of searched databases and relevant search strategies, and a summary of results, per group, for at least one of the desired outcomes.

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