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Tesi sul tema "Calcium Metabolism"

Autore: Grafiati
Pubblicato: 4 giugno 2021
Ultima modifica: 25 luglio 2025

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1

Eraso, Pichot Abel. "Adaptive regulation of calcium excitability and energy metabolism by CREB-dependent transcription in astrocytes: study of the mechanisms governing astrocyte plasticity." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/664170.

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Cada cop més evidencies suggereixen que els astròcits participen en les altes funcions cerebrals, controlant des de la transmissió sinàptica fins a les ones cerebrals globals i els processos d’aprenentatge i memòria. Diferents mecanismes han sigut proposats com a responsables d’aquests processos mediats per astròcits, entre ells, l’alliberació de gliotransmissors a partir de les senyals de calci així com la de lactat semblen els principals efectors. L’existència d’aquest control de les funcions cerebrals per part dels astròcits suggereix que aquestes cèl·lules poden regular les funcions cerebr
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2

Johnson, John Drysdale. "Stimulation of mitochondrial metabolism by calcium." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315046.

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3

Redmond, Jean Patricia. "Ethnic differences in calcium, phosphate and bone metabolism." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708405.

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4

O'Loughlin, Peter Damian. "Effects of growth and oophorectomy on calcium balance /." Title page, contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09pho516.pdf.

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5

Mody, Istvan. "Calcium regulation in long-term changes of neuronal excitability in the hippocampal formation." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25929.

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Abstract (sommario):
The regulation of calcium (Ca²⁺) was examined during long-term changes of neuronal excitability in the mammalian CNS. The preparations under investigation included the kindling model of epilepsy, a genetic form of epilepsy and long-term potentiation (LTP) of neuronal activity. The study also includes a discussion of the possible roles of a neuron-specific calcium-binding protein (CaBP). The findings are summarized as follows: 1) The distribution of CaBP was determined in cortical areas of the rat using a specific radioimmunoassay. The protein was found to have an unequal distribution in vario
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6

Barbosa, Erika Grasiela Marques de Menezes [UNESP]. "Perfil metabólico de cálcio e ósseo de pacientes soropositivos para HIV em uso ou não da terapia antirretroviral." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/88689.

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Abstract (sommario):
Made available in DSpace on 2014-06-11T19:23:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-29Bitstream added on 2014-06-13T18:09:51Z : No. of bitstreams: 1 barbosa_egmm_me_arafcf.pdf: 437958 bytes, checksum: 3c5ca7946a683a97660f6cc74c0cab06 (MD5)<br>A potência e a eficácia das terapias antirretrovirais (TARV) aumentaram a expectativa de vida dos pacientes infectados pelo vírus da imunodeficiência humana. Entretanto, resultados de vários estudos sugerem que estas terapias também podem produzir modificações metabólicas, tais como as doenças ósseas. O objetivo do presente estudo
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7

Pasanisi, F. "Clinical pharmacology of calcium antagonists." Thesis, University of Glasgow, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381477.

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8

Lirvall, Margareta. "Dynamics and gene expression of growth factor receptors in human cultured skin cells : effects of UV radiation and calcium on EGF- and PDGF-receptors /." Linköping : Univ, 2001. http://www.bibl.liu.se/liupubl/disp/disp2001/med674s.pdf.

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9

Efanov, Alexander. "Stimulation of insulin secretion independently from changes in cytosolic free Ca²⁺-concentration : studies with imidazolines and inositol polyphosphates /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3876-8/.

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10

Tsai, Jon A. "Parathyroid hormone-related protein (PTHrP), calcium and human osteoblast-like cells /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4174-2.

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11

Madrick, Tracy L. "The availability of calcium from various commercial sources of calcium carbonate and fortified food products." Thesis, Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/53228.

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Abstract (sommario):
Although the therapeutic benefits of calcium supplementation have yet to be fully determined, popular literature has promoted this practice to combat osteoporosis. This study examined the potential bioavailability of calcium from various supplement and antacid forms. Four dosage levels were studied for each of five sources, including leading supplements Caltrate and Os-Cal, two "calcium rich" antacids, Tums and Rolaids, and a calcium carbonate control. These samples were subjected to four gastric treatments in an in vitro digestion procedure designed to observe the influence of acid secretion
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12

Amrapali, Vishwanath Anjali. "The role of mitochondrial calcium homeostasis in presynaptic metabolism and neurotransmission : understanding how modulating mitochondrial metabolism affects neuronal physiology." Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS295.pdf.

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Bien que le cerveau n'occupe que 2 % de la masse corporelle, il consomme 20 % de l'énergie du corps. De la mouche au mammifère, la transmission synaptique neuronale consomme la plus grande quantité d'énergie (Attwell &amp; Laughlin, 2001). La transmission synaptique est un processus très plastique, sujet à des changements dans l'intensité et la synchronisation des tirs neuronaux. Par conséquent, pour répondre à la demande synaptique changeante, la production d'énergie doit également être flexible et coordonnée avec l'activité synaptique. Ce processus de production d'énergie à la demande a lieu
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13

Beggs, Louise Alice. "Evaluation of the problem solving method in nutrition education." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26164.

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The purpose of this study was to evaluate the problem solving method applied to a self-instructional material in nutrition education. A comparative evaluation design was employed to determine the value of a problem solving model reflected in a commercially developed material, referred to as the 'Calcium Calculator'. Data were collected using a quasi-experimental randomized group pretest, posttest research design. A panel of judges then evaluated the impact of the problem solving method in nutrition education. Three research questions were generated for the purpose of this study. The first in
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14

Gomes, Rocha Agostinho Manuel. "Calcium regulation in chloroplasts and the role of calcium-dependent phosphorylation of transketolase in carbon metabolism." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-153326.

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15

Ruschkowski, Sharon Rose. "Ovulation and calcium metabolism in white leghorn hens (Gallus gallus)." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29810.

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Calcium status is a major factor in the regulation of reproductive activity in the hen. Restriction of dietary calcium (Ca) or vitamin D (D) is assumed to cause cessation of ovulation through decreased plasma calcium concentrations. Several studies suggest that there may be a threshold level of ionized calcium (Cai) below which ovulation will not proceed. The objectives of this thesis were to determine how Cai concentration is involved in the process of ovulation by comparing Ca and D-deficient hens, that had ceased laying, with control birds that were laying normally. A secondary objective w
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16

Dawes, Michael W. "The formulation and validation of mathematical models of calcium metabolism." Thesis, City University London, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237825.

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17

Takasugi, Satoshi. "The effects of excess calcium on mineral metabolism in rats." Kyoto University, 2009. http://hdl.handle.net/2433/126539.

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Kyoto University (京都大学)<br>0048<br>新制・論文博士<br>博士(農学)<br>乙第12384号<br>論農博第2719号<br>新制||農||975(附属図書館)<br>学位論文||H21||N4493(農学部図書室)<br>27319<br>UT51-2009-K693<br>(主査)教授 松井 徹, 教授 久米 新一, 教授 廣岡 博之<br>学位規則第4条第2項該当
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18

Scheffler, Tracy Leigh. "AMP-activated protein kinase and muscle metabolism." Diss., Virginia Tech, 2012. http://hdl.handle.net/10919/38829.

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Abstract (sommario):
AMP-activated protein kinase (AMPK) is a major regulator of skeletal muscle metabolism with relevance to agriculture and human health. During the conversion of muscle to meat, the rate and extent of postmortem metabolism and pH decline largely determine pork quality development. Pigs with the AMPKγ3 R200Q mutation generate pork with low ultimate pH (pHu); this is attributed to high glycogen content, and greater â potentialâ to produce lactate and H+. We hypothesized that decreasing muscle phosphocreatine and creatine would decrease ATP buffering capacity, resulting in earlier terminatio
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19

Fujiwara(Tomita), Kyoko. "Clinical studies of the effect of food components on calcium or lipid metabolism." Kyoto University, 2014. http://hdl.handle.net/2433/193552.

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20

Martino, Paul F. "The effects of dantrolene on post exercise glucose uptake." Virtual Press, 1996. http://liblink.bsu.edu/uhtbin/catkey/1020145.

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Abstract (sommario):
The purpose of this investigation was to determine the relationship between calcium and glucose uptake following muscle contraction with the use of the calcium channel blocker dantrolene. In previous studies an exercise model has been used to investigate the role of calcium during post-exercise glucose uptake. This study utilized electrical stimulation. It has been shown that exercise-induced glucose uptake is calciummediated, but to date no one has shown that glucose transport induced by electrical stimulation is calcium-mediated. Twenty four male Sprague Dawley rats weighing 140 g were sacri
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21

Sampath, Vanitha. "The effects of calcium supplementation on adipocyte metabolism in overweight women /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.

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22

Campbell, Karen. "The relationship between calcium and metabolism in mouse eggs at fertilisation." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54106/.

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At fertilisation in mammals a series of Ca2+ oscillations are initiated that activate development. These Ca2+ oscillations cause the reduction of mitochondrial NAD+ and flavoproteins, suggesting that they might also stimulate changes in cytosolic ATP levels. Many events at fertilisation are triggered that require ATP; however, the changes in ATP during fertilisation are poorly defined. In this thesis intracellular C a2+ and ATP levels in individual m ouse eggs were m easured by monitoring the fluorescence of a C a 2+ dye (Oregon green bapta dextran) and lum inescence of firefly luciferase. Dur
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23

Mohammed, Samir M. M. "Calcium metabolism in sickle cell disease : possible link with sicklaemic osteoporosis." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292910.

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24

Outila, Terhi. "The effect of vitamin D status on calcium and bone metabolism." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/maa/skemi/vk/outila/.

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25

Batts, Timothy W. "Effects of Reduced Muscle Glycogen on Sarcoplasmic Reticulum (SR), Muscle and Exercise Performance." Diss., Virginia Tech, 2002. http://hdl.handle.net/10919/27244.

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Fatigue during exercise is associated with reduced muscle glycogen. However, evidence linking glycogen content to fatigue is lacking. In this study we examined whether reduced muscle glycogen content limited SR function or muscle performance. Two groups of female Sprague-Dawley rats were fasted for 24 hr and exercised for 90 min to reduce muscle glycogen; rats fasted after exercise formed the low glycogen (LG) group. Rats in the high glycogen (HG) group were allowed free access to food and a 5% sucrose solution. The LG group had 42% less muscle glycogen and 90% less glycogen associated with
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26

Barbosa, Erika Grasiela Marques de Menezes. "Perfil metabólico de cálcio e ósseo de pacientes soropositivos para HIV em uso ou não da terapia antirretroviral /." Araraquara :, 2013. http://hdl.handle.net/11449/88689.

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Orientador: Anderson Marliere Navarro<br>Banca: Alcyone Artioli Machado<br>Banca: Flavia Queiroga de Almeida<br>Resumo: A potência e a eficácia das terapias antirretrovirais (TARV) aumentaram a expectativa de vida dos pacientes infectados pelo vírus da imunodeficiência humana. Entretanto, resultados de vários estudos sugerem que estas terapias também podem produzir modificações metabólicas, tais como as doenças ósseas. O objetivo do presente estudo foi avaliar a qualidade óssea e marcadores de formação e reabsorção óssea em pacientes infectados pelo HIV em uso ou não da TARV. Foi realizado um
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27

Taylor, Megan Sands. "Calcium and Phosphorus Metabolism in Jersey and Holstein Cows During Early Lactation." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/29118.

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The objective of this dissertation was to assess the dynamics of calcium (Ca) and phosphorus (P) metabolism in dairy cattle. Hypocalcemia, or a drop in blood Ca, is a common condition near parturition. All cows experience some degree of hypocalcemia. Maintenance of blood Ca within the acceptable range of 8 to 10 mg/dl is a balancing act between the demand for Ca for milk production and the cow's homeostatic mechanisms to maintain blood Ca. These homeostatic mechanisms include bone resorption that is driven by Ca demand however both Ca and P are released when bone is resorbed. These times of bo
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28

Crouch, Michael Francis. "Inositol phospholipid turnover and pancreatic exocrine secretion /." Title page, contents and abstract only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phc9519.pdf.

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29

James, Andrew. "Metabolic regulation of the plasma membrane calcium pump in pancreatic ductal adenocarcinoma." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/metabolic-regulation-of-the-plasma-membrane-calcium-pump-in-pancreatic-ductal-adenocarcinoma(0533b59c-e6ee-41fb-ad32-cb4784eadfa1).html.

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Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of cancer with poor prognosis and limited treatment options. Since many patients present with metastatic disease and are thus ineligible for surgical resection, PDAC is almost ubiquitously fatal; new treatment options are therefore needed to combat this disease. A key hallmark of many cancers, including PDAC, is metabolic reprogramming and a shift towards a high glycolytic rate, known as the Warburg effect. This allows cancer cells to generate ATP in the face of hypoxia and to meet the increased metabolic requirements associated wit
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30

Alomaim, Haya. "Effects of Dietary Calcium on Body Composition and Lipid Metabolism in Rats." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37602.

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Abstract (sommario):
Calcium (Ca) intakes may affect cardiovascular disease risk by altering body weight/fat and serum lipid profile, but results have been inconsistent and the underlying mechanisms are not well understood. Thus, the effects of dietary Ca on body composition and lipid metabolism were examined in male Sprague-Dawley rats. Rats were fed high-fat, high-energy diets containing (g/kg) low (0.75Ca, 0.86 ± 0.05; 2Ca, 2.26 ± 0.02), normal (5Ca, 5.55 ± 0.08) or high (10Ca,11.03 ± 0.17; 20Ca, 21.79 ± 0.15) Ca for 10 weeks. At the end of the study the 0.75Ca group had lower (p < 0.05) body weight and fat mas
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31

Takagi, Hiroshi. "Effects of manipulating dietary cation-anion balance on calcium metabolism in sheep." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75683.

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Experiments were conducted to investigate the effect of reducing dietary anion-cation balance (AC-balance), defined as meq $ sp circ$(Sodium + Potassium)-(Chloride + Sulfur) S, on calcium (Ca) metabolism. Reducing the dietary AC-balance from +314 to $-22$ (meq kg$ sp{-1}$ dry matter (DM)) did not affect plasma Ca level but reduced Ca retention mainly due to a 10-fold increase in urinary Ca excretion with similar rate of apparent absorption. It also decreased urine pH and titratable acidity. The response to induced hypocalcemia created by the infusion of 4.6% EDTA solution revealed that reducin
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32

Clifton-Bligh, Phillip. "Studies in Calcium, Parathyroid Hormone and Calcitonin Metabolism and Associated Skeletal Disorders." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18554.

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The association of hyperparathyroidism with Paget’s disease, the changes in bone mineral density after parathyroidectomy, the surgical experience with a large number of patients with hyperparathyroidism, the findings of stable bone mineral density and renal function in hyperparathyroid patients during long term follow up, and, most importantly, in a large study continued over several decades, the reduced life expectancy of patients with primary hyrperparathyroidism are described. The effective use of salmon calcitonin in a large number of patients with Paget’s disease, the use of pentagastrin
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33

Allen, Bruce Gordon. "Studies on the reaction cycle of the calcium transport atpase from human erythrocytes." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24458.

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Abstract (sommario):
The plasma membrane calcium-transport ATPase plays a major role in maintaining the low cytosolic calcium concentrations required for normal cellular function. Calcium, magnesium, calmodulin and lanthanum have been shown to alter the activity of the calcium-stimulated, magnesium-dependent ATPase activity in human erythrocytes. In an attempt to examine the reaction sequence of the (Ca²⁺ + Mg²⁺)-ATPase, the effects of these agents on the kinetics of calcium dependent phosphoprotein formation, the first step in the partial reaction sequence, were examined. Calmo-dulin-depleted erythrocyte membra
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34

Koenig, Vicki C. "Effect of calcium level and source on plasma total and lipoprotein cholesterol in men under controlled dietary conditions." Thesis, Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/64565.

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A metabolic study was conducted with 23 men to determine the effects on plasma lipids and lipoproteins of a high calcium intake from two sources compared to a normal level of calcium intake over an eight week controlled feeding period. Three diet treatments were examined: 1) high dietary calcium mainly from dairy sources (1600-1800 mg/day), 2) high dietary calcium supplied by a CaCO₃ supplement (1600-1800 mg/day), and 3) normal dietary calcium intake from mixed sources (600-800 mg/day). Fat, carbohydrate and protein were provided in the ratio of percent kcal as 40:49:11. Nutrient, cholesterol
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35

Hagström, Emil. "Metabolic disturbances in relation to serum calcium and primary hyperparathyroidism /." Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6893.

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36

Challa, J. "Phosphorus and calcium metabolism in growing calves with special emphasis on phosphorus homeostasis." Thesis, University of Reading, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371434.

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37

Шапкін, Вадим Евгенійович, and V. E. Shapkin. "Calcium metabolism changes as a formation mechanism of diabetic foot in geriatric patients." Thesis, ХНМУ, 2017. http://repo.knmu.edu.ua/handle/123456789/15813.

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Identified differences of calcium metabolism indicate signs of calcium malabsorption in DM patients and the processes of bone resorption intensification. This allows to conclude that calcium metabolism status (in particular, the severity of bone resorption) has significance at the development of diabetic hard tissue foot lesions as well as diabetic neuropathies and angiopathies. Insulin has a significant anabolic effect. It is known that a insulin production decreasing leads to the bone mineralization decreasing, reducing of the calcium blood serum level, increasing of the calcium urine
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38

Huo, Jiuzhou. "Regulation of Mitochondrial Calcium Dynamics in Striated Muscle Function." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595846761184679.

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39

Yip, Ming Fai Freddy Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "The role of Myo1c phosphorylation in GLUT4 translocation." Publisher:University of New South Wales. Biotechnology & Biomolecular Sciences, 2009. http://handle.unsw.edu.au/1959.4/43648.

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Glucose is a primary and essential energy source for humans. It is broken down from complex carbohydrates in the diet and absorbed across the gut epithelium into the blood stream. Glucose homeostasis is important as hyperglycermia causes damage of pancreatic and peripheral cells. In response to a meal glucose is principally taken up by fat and muscle tissues and this response is activated by insulin release from pancreatic beta cells. Insulin stimulates the translocation of GLUT4 from the intracellular storage vesicles to the plasma membrane in fat and muscle cells. Although many proteins have
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40

Raposo, João Filipe Cancela Santos. "A regulação endócrina dos balanços de cálcio." Doctoral thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2004. http://hdl.handle.net/10362/5523.

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RESUMO: As concentrações circulantes de cálcio são notavelmente constantes a despeito das variações diárias na absorção intestinal e na eliminação renal deste elemento. A regulação da calcémia é um sistema complexo que compreende vários factores controladores (a calcémia, a fosforémia, as concentrações circulantes de paratormona (PTH) e calcitriol além de muitos outros factores como hormonas esteróides em geral, outros iões como o magnésio e outros factores hormonais) e vários órgãos alvo (glândulas paratiroideias, osso, rim e intestino). As respostas dos órgãos alvo também são muito variadas
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41

Thatcher, Nicola M. "Cerebral metabolism, calcium and zinc during excitotoxic challenge : a multinuclear magnetic resonance spectroscopy study." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260992.

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42

Matsui, Tohru. "The Nutritional and Physiological Role of Calcitonin on Calcium and Phosphorus Metabolism in Sheep." Kyoto University, 1985. http://hdl.handle.net/2433/77697.

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43

Message, Chris. "The effect of modified waxy maize starch on calcium bioavailability, with special reference to the rat." Thesis, Oxford Brookes University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262170.

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44

Andrade, Carolina de Matos Figueiredo de [UNESP]. "Análise do consumo de extato hidrossolúvel de soja na qualidade do tecido ósseo de ratos jovens adultos." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/132935.

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Submitted by CAROLINA DE MATOS FIGUEIREDO null (carolinaf.nutri@hotmail.com) on 2016-01-24T19:05:39Z No. of bitstreams: 1 Dissertação PDF.pdf: 691008 bytes, checksum: 2cf64d69340e51ebd81408264bdb85d9 (MD5)<br>Approved for entry into archive by Ana Paula Grisoto (grisotoana@reitoria.unesp.br) on 2016-01-25T16:38:45Z (GMT) No. of bitstreams: 1 andrade_cmf_me_araca.pdf: 691008 bytes, checksum: 2cf64d69340e51ebd81408264bdb85d9 (MD5)<br>Made available in DSpace on 2016-01-25T16:38:45Z (GMT). No. of bitstreams: 1 andrade_cmf_me_araca.pdf: 691008 bytes, checksum: 2cf64d69340e51ebd81408264bdb85d9
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Andrade, Carolina de Matos Figueiredo de. "Análise do consumo de extato hidrossolúvel de soja na qualidade do tecido ósseo de ratos jovens adultos /." Araçatuba, 2016. http://hdl.handle.net/11449/132935.

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Orientador: Mario Jefferson Quirino Louzada<br>Banca: Paulo César Ciarlini<br>Banca: Cáris Maroni Nunes<br>Resumo: A soja é uma leguminosa rica em proteínas, fonte de cálcio e isoflavonas. Um dos possíveis efeitos das isoflavonas é de reduzir a perda óssea quando há uma deficiência de estrogênio. A proposta desse estudo foi analisar a influência da dieta suplementada com extrato hidrossolúvel de soja (EHS) na massa óssea de ratos adultos jovens de ambos os sexos. Foram utilizados 40 ratos Novergicus Albinus linhagem Wistar adultos jovens e saudáveis, aleatoriamente separados em quatro grupos:
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46

Santini, Olivier. "Effects of copper on calcium metabolism and detoxification mechanisms in freshwater bivalve species of "Anodonta." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0397/document.

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Le Cuivre (Cu) appartient aux métaux majeurs contaminant les écosystèmes dulcicoles européens. Les bivalves sont des filtreurs qui bioaccumulent fortement les métaux lourds comme le Cu, lequel, en excès cause de graves troubles métaboliques, et physiologiques. Le but de cette thèse est d'étudier les mécanismes de toxicité et de détoxication du cuivre chez Anodonta cygnea et Anodonta anatina, bivalves largement répandus dans les eaux continentales. L'effet du Cu a d'abord été étudié sur le transport cellulaire du calcium (Ca). Le Ca intervient dans de nombreux processus biologiques et le métabo
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Anderson, Paul Hamill. "The regulation of Vitamin D metabolism in the kidney and bone." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09pha5486.pdf.

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Includes bibliographical references (leaves 226-273.) Investigates the regulation of the expression of CYP27B1, CYP24 and vitamin D receptor (VDR) mRNA, both in the bone and in the kidney, with the aim to determine whether the regulation of the vitamin D metabolism in the bone is independent from that in the kidney. The effects of age, dietary calcium and vitamin D status on the expression of these genes in both the kidney and the bone, as well as on a number of biochemical factors known to regulate the renal metabolism of 1,25D, such as PTH, calcium and 1,25D itself, were examined. CYP27B1 mR
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Li, Yiming. "Ryanodine receptors in calcium signaling pathways." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/710.

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Calcium (Ca2+) plays an important role as a second messenger, transmitting the message of arrival of stimuli such as hormones and neurotransmitters to the intracellular system that carries out the cellular response to the stimulus. The universality of Ca2+ as an intracellular messenger depends on its enormous versatility. This versatility is exploited to control processes as diverse as fertilization, proliferation, development, learning and memory, contraction and secretion, and must be accomplished within the context of Ca2+ being highly toxic. Ryanodine receptors (RyRs) and inositol trisphos
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Kerry, David Michael Kerry. "Regulation of the rat 25-hydroxyvitamin D3 24-hydroxylase gene promoter by 1,25(OH)2D3 /." Title page, contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phk416.pdf.

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Jelic, Petra. "Effects of chronic ethanol consumption, ethanol withdrawal, and calcium channel antagonists on lipid metabolism in adipose tissue of TO mice." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285573.

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