Letteratura scientifica selezionata sul tema "Cancer – Genetic aspects"

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Articoli di riviste sul tema "Cancer – Genetic aspects"

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Hold, Georgina L., and M. Emad El-Omar. "Genetic aspects of inflammation and cancer." Biochemical Journal 410, no. 2 (February 12, 2008): 225–35. http://dx.doi.org/10.1042/bj20071341.

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Chronic inflammation is involved in the pathogenesis of most common cancers. The aetiology of the inflammation is varied and includes microbial, chemical and physical agents. The chronically inflamed milieu is awash with pro-inflammatory cytokines and is characterized by the activation of signalling pathways that cross-talk between inflammation and carcinogenesis. Many of the factors involved in chronic inflammation play a dual role in the process, promoting neoplastic progression but also facilitating cancer prevention. A comprehensive understanding of the molecular and cellular inflammatory
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Hudler, Petra. "Genetic Aspects of Gastric Cancer Instability." Scientific World Journal 2012 (2012): 1–10. http://dx.doi.org/10.1100/2012/761909.

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Unravelling the molecular mechanisms underlying gastric carcinogenesis is one of the major challenges in cancer genomics. Gastric cancer is a very complex and heterogeneous disease, and although much has been learned about the different genetic changes that eventually lead to its development, the detailed mechanisms still remain unclear. Malignant transformation of gastric cells is the consequence of a multistep process involving different genetic and epigenetic changes in numerous genes in combination with host genetic background and environmental factors. The majority of gastric adenocarcino
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Olsson, R. "Hepatitis and Cancer: Genetic Aspects." Scandinavian Journal of Gastroenterology 31, sup220 (January 1996): 115–20. http://dx.doi.org/10.3109/00365529609094761.

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R., Bohiltea. "Genetic aspects of endometrial cancer." Gineco.eu 12, no. 1 (March 20, 2016): 29–32. http://dx.doi.org/10.18643/gieu.2016.29.

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Karlan, Beth Y., and Deborah Krakow. "Genetic aspects of ovarian cancer." Current Opinion in Obstetrics and Gynecology 6, no. 1 (February 1994): 105. http://dx.doi.org/10.1097/00001703-199402000-00017.

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Steel, M., A. Thompson, and J. Clayton. "Genetic aspects of breast cancer." British Medical Bulletin 47, no. 2 (1991): 504–18. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072488.

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Latil, Alain, and R. Lidereau. "Genetic aspects of prostate cancer." Virchows Archiv 432, no. 5 (May 19, 1998): 389–406. http://dx.doi.org/10.1007/s004280050183.

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Hecht, Jonathan L., and George L. Mutter. "Molecular and Pathologic Aspects of Endometrial Carcinogenesis." Journal of Clinical Oncology 24, no. 29 (October 10, 2006): 4783–91. http://dx.doi.org/10.1200/jco.2006.06.7173.

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Abstract (sommario):
Endometrial cancer is the most common gynecological malignancy, with 41,000 new cases projected in the United States for 2006. Two different clinicopathologic subtypes are recognized: the estrogen-related (type I, endometrioid) and the non–estrogen-related types (type II, nonendometrioid such as papillary serous and clear cell). The morphologic differences in these cancers are mirrored in their molecular genetic profile with type I showing defects in DNA-mismatch repair and mutations in PTEN, K-ras, and beta-catenin, and type II showing aneuploidy and p53 mutations. This article reviews the ge
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Hill, R. P. "Genetic aspects of metastasis." Current Opinion in ONCOLOGY 2, no. 1 (February 1990): 157–62. http://dx.doi.org/10.1097/00001622-199002000-00026.

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Krasteva, M., Sv Angelova, and Zl Gospodinova. "Molecular-Genetic Aspects of Breast Cancer." Acta Medica Bulgarica 41, no. 2 (December 1, 2014): 67–79. http://dx.doi.org/10.1515/amb-2014-0024.

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Summary Breast cancer is the most frequent malignancy among women. Advances in breast cancer knowledge have deciphered the involvement of a number of tumor suppressor genes and proto-oncogenes in disease pathogenesis. These genes are part of the complex biochemical pathways, which enable cell cycle control and maintenance of genome integrity. Their function may be disrupted as a result of alterations in gene sequence or misregulation of gene expression including alterations in DNA methylation pattern. The present review summarizes the main findings on major breast cancer related genes BRCA1/2,
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Tesi sul tema "Cancer – Genetic aspects"

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Fransén, Karin. "Molecular genetic aspects of colorectal cancer development /." Linköping : Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med878s.pdf.

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Steggles, Naomi. "Psychological aspects of genetic testing for cancer." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271020.

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Cheung, Chin-ling, and 張展寧. "Genetic analysis of nasopharyngeal cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44659866.

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Hayat, Roshanai Afsaneh. "Psychological and Behavioral Aspects of Receiving Genetic Counseling for Hereditary Cancer." Doctoral thesis, Uppsala universitet, Vårdvetenskap, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128870.

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Abstract (sommario):
The overall aims of this thesis were to investigate psychological and behavioral effects of receiving cancer genetic counseling for breast, ovarian and colorectal cancer and/or with a family history of these cancer types and to determine whether counselees’ informational needs were met. Study I was performed 3-7 years post-counseling. Participants (n=214) reported a relatively high level of anxiety but a low level of depression compared to cancer patients in general. However, there was no indication that the distress experienced was due to the counseling. Moderate changes in life and family re
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陳安安 and On-on Annie Chan. "Methylation in colorectal cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B25256312.

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Tai, Lai-shan, and 戴麗珊. "Molecular genetic characterizations of human non-small cell lung cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B31375315.

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Zhao, Wei, and 趙煒. "BRAF mutation and aberrant methylation of gene promoters in the pathogenesis of gastrointestinal tract adenocarcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36718464.

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Wright, C. M. "The prognostic significance of microsatellite instability in sporadic stage C colorectal cancer." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28955.

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Abstract (sommario):
Identification and understanding of the molecular events involved in colorectal cancer (CRC) pathogenesis should lead to better comprehension of the disease process, hopefully leading to better prognostic stratification, and as a result more targeted treatment regimens and improved patient outcomes. A sub group of sporadic CRC exhibit microsatellite instability (MSI). MSI is seen when the fidelity of DNA replication is impaired. Cancers may be categorized as MSI-high (MSI-H), MSI-low (MSI-L), or microsatellite stable (MSS), according to the degree of MSI exhibited. This research proj
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黃鳳如 and Fung-yu Huang. "Molecular and cytogenetic analysis of cervical and vulvar cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B26662188.

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Khoo, Ui-soon, and 邱瑋璇. "Genetic susceptibility to gynaecological cancers in the Chinese population." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B25257365.

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Libri sul tema "Cancer – Genetic aspects"

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Côté, Gilbert B. Cancer cytogenetics lookup. Ontario, Canada: Canell, 1999.

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1959-, Eeles Rosalind A., ed. Genetic predisposition to cancer. London: Chapman & Hall Medical, 1996.

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1959-, Eeles Rosalind A., ed. Genetic predisposition to cancer. 2nd ed. London: Arnold, 2004.

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W, Weber, Mulvihill John J. 1943-, and Narod Steven A, eds. Familial cancer management. Boca Raton: CRC Press, 1996.

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Chung, Daniel C., and Daniel A. Haber. Principles of clinical cancer genetics: A handbook from the Massachusetts General Hospital. Edited by Massachusetts General Hospital. New York: Springer, 2010.

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K, Cowell John, ed. Molecular genetics of cancer. 2nd ed. Oxford: Bios, 2001.

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International Research Conference on Familial Cancer (2nd 1995 Basel, Switzerland). Hereditary cancer: Second International Research Conference on Familial Cancer, Basel, September 11-15, 1995. Edited by Müller Hj, Scott R. J, and Weber W. Basel: Karger, 1996.

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O, Tollefsbol Trygve, ed. Cancer epigenetics. Boca Raton: CRC Press/Taylor & Francis Group, 2009.

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Macadam, Ian. Race against cancer: A genetic approach to control of cancer. Edinburgh: I. Macadam, 1996.

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Hoda, Anton-Guirgis, and Lynch Henry T, eds. Biomarkers, genetics, and cancer. New York: Van Nostrand Reinhold, 1985.

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Capitoli di libri sul tema "Cancer – Genetic aspects"

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Goddard, Audrey D., and Ellen Solomon. "Genetic Aspects of Cancer." In Advances in Human Genetics 21, 321–76. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3010-7_4.

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Chichakli, Ramsey N., and Jeffrey R. Gingrich. "Genetic Aspects of Urologic Malignancies." In Inherited Cancer Syndromes, 205–40. New York, NY: Springer New York, 2004. http://dx.doi.org/10.1007/0-387-21596-4_9.

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Sobels, F. H. "Genetic Aspects of Cancer Epidemiology." In Antimutagenesis and Anticarcinogenesis Mechanisms, 459–63. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5182-5_40.

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MacKay, J., and M. Steel. "Genetic Aspects of Human Breast Cancer." In High-Risk Breast Cancer, 45–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73718-3_3.

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Greene, M. H., and S. J. Bale. "Genetic Aspects of Cutaneous Malignant Melanoma." In Recent Results in Cancer Research, 144–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82641-2_12.

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Aspinwall, Lisa G., Jennifer M. Taber, Wendy Kohlmann, and Sancy A. Leachman. "Psychological Aspects of Hereditary Cancer Risk Counseling and Genetic Testing." In Psychological Aspects of Cancer, 31–64. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4866-2_3.

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Yaghmaie, Marjan, Mohammad Ahmadvand, Ali-akbar Nejati Safa, and Hossein Pashaiefar. "Genetic, Hematologic and Psychological Aspects of Leukemia." In Cancer Genetics and Psychotherapy, 667–755. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64550-6_14.

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Backer, J. M., and C. V. Hamby. "Genetic control of metastasis." In Molecular Aspects of Cancer and its Therapy, 1–19. Basel: Birkhäuser Basel, 1998. http://dx.doi.org/10.1007/978-3-0348-8946-9_1.

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Sobti, R. C., Adnan Issa AL-Badran, Khadijeh Onsori, and S. K. Sharma. "Bladder Cancer: Genetic and Epidemiological Factors Involved in its Genesis." In Some Aspects of Chromosome Structure and Functions, 207–24. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0334-6_19.

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McIvor, R. Scott. "Gene Therapy for Genetic Disease and Cancer." In Animal Cell Technology: Basic & Applied Aspects, 7–12. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-017-0728-2_2.

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Atti di convegni sul tema "Cancer – Genetic aspects"

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Rotaru, Ludmila, and Tudor Rotaru. "Ovarian cancer – genetic aspects." In XIth International Congress of Geneticists and Breeders from the Republic of Moldova. Scientific Association of Geneticists and Breeders of the Republic of Moldova, Institute of Genetics, Physiology and Plant Protection, Moldova State University, 2021. http://dx.doi.org/10.53040/cga11.2021.041.

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Mishatkina, T. V., S. B. Melnov, and E. V. Snytkov. "GENETIC AND SOCIO-BIOETHICAL ASPECTS OF BREAST CANCER PREDISPOSITION AMONG WOMEN OF SLAVIC AND CENTRAL ASIAN ETHNIC GROUPS." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute, 2021. http://dx.doi.org/10.46646/sakh-2021-1-64-68.

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The publication was prepared based on the materials of the implementation of the joint Belarusian-Uzbek two-year scientific project “Genetic and socio-bioethical aspects of predisposition to breast cancer for women of Slavic and Central Asian ethnic groups.” The results of studies carried out from October 01, 2020 to March 15, 2021 are presented.
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Ferreira, Nancy, Darley Ferreira, and Thais Ferreira. "GENETIC EVALUATION OF MICROCALCIFICATIONS AS A PROGNOSTIC FACTOR." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2101.

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Introduction: Breast cancer is the most recurring type of cancer among women, with reduced mortality at an initial stage of lesion. From a radiological perspective, perceived microcalcifications may be associated with histological findings such as proliferative injuries with or without atypical features and ductal carcinoma in situ. Currently, percutaneous and vacuum biopsies allow for the correlation between anatomoradiological and identification of previous lesions and those that offer the risk of cancer. No biomarker has been established to predict the risk of cancer in women diagnosed with
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Assis, Amilcar Alves, Mauro Passos, Rodrigo Kouzak, Karoline Evangelista, and Natasha Caldas. "BREAST CANCER IN YOUNG PATIENTS: PROGNOSTIC AND PROFILE EPIDEMIOLOGICAL ANALYSIS IN A TERTIARY HOSPITAL." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2093.

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Breast cancer is the second most prevalent and first in mortality in Brazilian women. Its incidence has increased in recent years in all age groups. According to the Instituto Nacional do Câncer in 2019, 59,700 new cases of breast cancer are expected, with an estimated risk of 56.33 cases per 100 women. The diagnosis of breast cancer is more frequent in women after 50 years of age; it is estimated that only 25% of all cases occur in women below the age of 50 years; however, there was a literature consensus that tumors in this young age group have a worse prognosis, both because they are biolog
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Esteban, Jorge Illarramendi, Montserrat Alvarellos, Mercedes Rodriguez, Amaya Zabalza, and José Juan Illarramendi. "IRON OVERLOAD IN A BREAST CANCER PATIENT WITH A HOMOZYGOUS MUTATION IN THE HFE HEMOSTATIC IRON REGULATOR GENE: CONSIDERATIONS REGARDING THE USE OF ADJUVANT HORMONE THERAPY." In Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2082.

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Introduction: Homozygous mutations in the HFE gene are among the causes of iron overload worldwide. Several reports suggest an increased risk of breast cancer (BC) in these patients, although there are controversial evidences on this subject. There is some discussion on the tolerance to some BC adjuvant therapies in these patients regarding aspects like the potential cardiotoxicities. Information on adjuvant hormone therapy in this setting is very limited. Case report: A 65-year- -old woman was treated with segmental resection in the left breast and selective biopsy of the sentinel node in Apr
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Kumar, N., A. Mishra, and S. Deo. "169 A prospective interventional study evaluating awareness and knowledge about genetic aspects of breast cancer and the effect of educational intervention: a real-life experience." In IGCS 2020 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2020. http://dx.doi.org/10.1136/ijgc-2020-igcs.147.

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onoda, Takashi, and Yasunobu Ito. "Academic Researchers' Voluntary Incentives in Technology Transfer: An ethnographic case study of genome science." In 15th International Conference on Applied Human Factors and Ergonomics (AHFE 2024). AHFE International, 2024. http://dx.doi.org/10.54941/ahfe1005108.

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The predominant contributors to the advancement of medical devices have traditionally resided within the industrial sector. Nevertheless, owing to recent progress in open innovation and other contributing factors, academia has experienced a notable surge in research and development activities. In 2015, the Japanese government inaugurated the Japan Agency for Medical Research and Development (AMED), aspiring to emulate the National Institutes of Health (NIH) in the United States, with the objective of fostering the creation of medical devices originating from academic endeavors. In the realm of
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Руда, М. Г. "Legal regulation of the use of biological collections as a "pillar" of genetic research." In XXIII Международная научная конференция «Цивилизация знаний: российские реалии» «Цивилизационные задачи современного правоведения: наука, образование, практика» (стратегическая панель). Crossref, 2022. http://dx.doi.org/10.18137/cz22.2022.65.55.001.

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Abstract (sommario):
В статье рассматриваются изменения, произошедшие под воздействием механизмов глобализации и интеграции. В первую очередь, это отразилось в изменении вектора эволюции основных тенденций использования материала биологических коллекций как «фундамента» генетических исследований в различных областях науки и практики. К ним относятся, в частности, исследования биологического разнообразия и оценка негативного антропогенного воздействия на окружающую среду. Кроме того, с помощью прогностического, статистического и аксиологического методов сделан ряд важных выводов о возможных последствиях такого возд
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Misek, Sean, Aaron Fultineer, Jeremie Kalfon, Javad Noorbakhsh, Isabella Boyle, Joshua Dempster, Lia Petronio, et al. "Defining the landscape of cancer vulnerabilities that are engendered by germline genetic variation." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.553030.

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Sato, Misako, Mitsutaka Kadota, Binwu Tang, Yu-an Yang, Mengge Shan, Jia Weng, Michael Welsh та ін. "Abstract B029: Dissecting out the tumor suppressor aspect of TGF-β in breast cancer using integrated genomics". У Abstracts: AACR Special Conference on Advances in Breast Cancer Research: Genetics, Biology, and Clinical Applications - October 3-6, 2013; San Diego, CA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1557-3125.advbc-b029.

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Rapporti di organizzazioni sul tema "Cancer – Genetic aspects"

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Tipton, Kelley, Brian F. Leas, Emilia Flores, Christopher Jepson, Jaya Aysola, Jordana Cohen, Michael Harhay, et al. Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Health and Healthcare. Agency for Healthcare Research and Quality (AHRQ), December 2023. http://dx.doi.org/10.23970/ahrqepccer268.

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Objectives. To examine the evidence on whether and how healthcare algorithms (including algorithm-informed decision tools) exacerbate, perpetuate, or reduce racial and ethnic disparities in access to healthcare, quality of care, and health outcomes, and examine strategies that mitigate racial and ethnic bias in the development and use of algorithms. Data sources. We searched published and grey literature for relevant studies published between January 2011 and February 2023. Based on expert guidance, we determined that earlier articles are unlikely to reflect current algorithms. We also hand-se
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