Bibliografie tematiche / Cardiovascular conditions

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Letteratura scientifica selezionata sul tema "Cardiovascular conditions"

Autore: Grafiati
Pubblicato: 12 aprile 2025

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Articoli di riviste sul tema "Cardiovascular conditions"

1

&NA;. "MANAGING CARDIOVASCULAR CONDITIONS". Nursing 22, n. 6 (giugno 1992): 76–81. http://dx.doi.org/10.1097/00152193-199206000-00027.

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Miller, Dylan V., e William D. Edwards. "Cardiovascular tumor-like conditions". Seminars in Diagnostic Pathology 25, n. 1 (febbraio 2008): 54–64. http://dx.doi.org/10.1053/j.semdp.2007.10.003.

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Dickson, Victoria Vaughan, e Gail D'Eramo Melkus. "Precision Health in Cardiovascular Conditions". Journal of Cardiovascular Nursing 37, n. 1 (gennaio 2022): 56–57. http://dx.doi.org/10.1097/jcn.0000000000000879.

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Hojman, Lia, e Claudio Karsulovic. "Cardiovascular Disease-Associated Skin Conditions". Vascular Health and Risk Management Volume 18 (febbraio 2022): 43–53. http://dx.doi.org/10.2147/vhrm.s343319.

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Hariom, Senthil Kumar, e Everette Jacob Remington Nelson. "Cardiovascular adaptations in microgravity conditions". Life Sciences in Space Research 42 (agosto 2024): 64–71. http://dx.doi.org/10.1016/j.lssr.2024.05.001.

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Romanenko, I. G., D. Yu Kryuchkov, S. M. Gorobets, A. A. Dzhereley e S. A. Bobkova. "Urgent cardiovascular conditions in dental practice". Stomatologiya 96, n. 6 (2017): 56. http://dx.doi.org/10.17116/stomat201796656-59.

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Tull, Thomas, e Sonya Abraham. "Inflammatory rheumatic conditions and cardiovascular disease". Clinical Medicine 8, n. 6 (1 dicembre 2008): 635.2–636. http://dx.doi.org/10.7861/clinmedicine.8-6-635a.

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Gaddy, Jeremiah D., Kathleen T. P. Davenport e Brian C. Hiestand. "Cardiovascular Conditions in the Observation Unit". Emergency Medicine Clinics of North America 35, n. 3 (agosto 2017): 549–69. http://dx.doi.org/10.1016/j.emc.2017.03.004.

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Chope, Katherine B. "Cardiac/Cardiovascular Conditions Affecting Sport Horses". Veterinary Clinics of North America: Equine Practice 34, n. 2 (agosto 2018): 409–25. http://dx.doi.org/10.1016/j.cveq.2018.04.001.

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Cuetter, A. "Neurologic conditions affecting the cardiovascular system". Current Problems in Cardiology 15, n. 9 (settembre 1990): 478–568. http://dx.doi.org/10.1016/0146-2806(90)90006-c.

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Tesi sul tema "Cardiovascular conditions"

1

FEVOLA, ELISA. "Boundary conditions estimation techniques for cardiovascular modeling". Doctoral thesis, Politecnico di Torino, 2022. http://hdl.handle.net/11583/2972100.

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Arif, Sayqa. "Investigating the role of nitric oxide clones in cardiovascular conditions". Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5299/.

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Previously thought to be inert, nitrite is now deemed to be an important endogenous source of nitric oxide (NO), particularly during hypoxia and ischaemia. Largely animal and some limited human studies propose a role for nitrite in ‘hypoxic vasodilatation’ and ischaemia-reperfusion injury. One study explores the effect of systemic nitrite infusion on cardiac and peripheral haemodynamic parameters in healthy subjects, during normoxia and hypoxia. Despite a lack of observed effects in healthy subjects, a study performed in patients with heart failure during normoxia demonstrated favourable haemodynamic effects on cardiac output, albeit at high doses of nitrite. In patients undergoing coronary artery bypass surgery, low dose nitrite infusion afforded protection against ischaemia-reperfusion injury. Several mechanisms of nitrite reduction to NO have been described and remain to be fully elucidated. The role of one of these putative mechanisms, namely mitochondrial aldehyde dehydrogenase (ALDH2) was explored during normoxia and hypoxia. Ex vivo human vascular ring studies confirmed ALDH2 as an important nitrite reductase, in contrast to in vivo observations in the forearm vasculature, suggesting that numerous mechanisms are involved in vivo which are harder to isolate. Furthermore, this hypoxia vasodilatory role was not replicated in with GTN in the human forearm vasculature.
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Adeyemi, Oladipupo. "Exploring novel applications for ursodeoxycholic acid in the treatment of cardiovascular conditions". Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/39570.

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As a bile acid, ursodeoxycholic acid (UDCA) is found endogenously formed in humans and other mammals where it is primarily involved in lipid metabolism. It is approved under a number of different brand names for the treatment of gallstones and Primary Billiary Cholangitis (PBC). Previous studies in cardiac cell models of Intrahepatic Cholestasis of Pregnancy (ICP) have demonstrated that UDCA can also be protective against the conduction slowing effects of the bile acid, taurocholic acid (TC). Therefore, this thesis aimed to identify novel applications for UDCA in the treatment of fetal arrhythmiasin ICP. It describes the development of a novel isolated-perfused neonatal rat heart model as a model of the fetal heart (FH) and an adult female rat heart model as a model of the maternal heart (MH) for evaluating the mechanism of bile acid induced arrhythmias. Using optical mapping and electrocardiogram (ECG) recording techniques, it separately evaluated TC effects in the atria and ventricles of the FH and compared them to effects in the MH model. It also evaluated the effects of UDCA in ischemia in a pilot study. It was observed that TC treatment induced significant conduction slowing in both the atria (ECG PR interval prolongation) and ventricles of the FH, but as occurs in ICP, these effects were absent or less pronounced in the MH model. Interestingly, co-administration of UDCA with TC was protective as it inhibited the observed conduction slowing effects. Using selective cardiac calcium channel blockers, it demonstrated that the conduction slowing effects of TC were mediated by blockade of the T-type calcium channel subtype. This was confirmed using the patch clamp technique that demonstrated that TC reduces the calcium current amplitude in neonatal rat and adult human fetal cardiomyocytes and this effect was inhibited with UDCA treatment. No beneficial effects were identified for UDCA in the treatment of acute global ischemia.
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Shi, Yubing. "Lumped-parameter modelling of cardiovascular system dynamics under different healthy and diseased conditions". Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/4198/.

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Cardiovascular disease is the most common cause of death in the modern society, and research into the diagnosis and treatment of cardiovascular diseases is an urgent task. Lumped-parameter mathematical modelling as an efficient and effective research technique has been extensively applied in the cardiovascular dynamics research, and has achieved enormous success in assisting the cardiovascular physiology study. This thesis reports a coherent work of lumped-parameter cardiovascular modelling based on some selected works that the author has conducted and published in the past several years. After a critical and comprehensive review of the concurrent lumped-parameter modelling technique, an improved lumped-parameter model that effectively describes the important cardiovascular features of heart valve dynamics and atrial-ventricular septum motion is presented. The model is then adapted to study several application cases of typical heart failure condition with ventricular assist device support, and extension of the lumped-parameter modelling for the optimisation of a pulsatile bioreactor in cardiovascular tissue engineering study. Some on-going works and future directions are also introduced. The reported modelling studies are useful for the cardiovascular physiology research and design optimisation of cardiovascular prosthetic organs.
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D'Ascenzi, Flavio. "Atrial function and loading conditions in athletes". Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-134873.

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Intensive training is associated with hemodynamic changes that typically induce an enlargement of cardiac chamber. Despite LA dilatation in athletes has been interpreted as a benign adaptation, little evidence is available. The aim of this thesis is to demonstrate that LA size changes in response to alterations in loading conditions and to analyse atrial myocardial function in athletes through the application of novel echocardiographic techniques. We found that top-level athletes exhibit a dynamic morphological and functional LA remodelling, induced by training, with an increase in reservoir and conduit volumes, but stable active volume. Training causes an increase in biatrial volumes which is accompanied by normal filling pressures and stiffness. These changes in atrial morphology are not associated with respective electrical changes. Extending the evidence from adult athletes to children, we found that training-induced atrial remodelling can occur in the early phases of the sports career and is associated with a preserved biatrial function. Finally, in a meta-analysis study of the available evidence we demonstrated that atrial function and size are not affected by aging. In conclusions, athlete’s heart is characterized by a physiological biatrial enlargement. This adaptation occurs in close association with LV cavity enlargement, is dynamic and reversible. This increase in biatrial size is not intrinsically an expression of atrial dysfunction. Indeed, in athletes the atria are characterized by a preserved reservoir function, normal myocardial stiffness, and dynamic changes in response to different loading conditions.
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Brauer, Paula Mae. "Familial aggregation of diabetes, hypertension and cardiovascular conditions in a case-control study of colorectal neoplasia". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0023/NQ49836.pdf.

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Rodier, Marion. "Impact du t-PA sur les taux cérébraux de BDNF en conditions physiologiques et sur les taux circulants en conditions ischémiques : études chez l' Homme et chez l'animal". Thesis, Dijon, 2014. http://www.theses.fr/2014DIJOS054/document.

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L’objectif de ce travail a été de tester l’hypothèse selon laquelle l’effet bénéfique de l’administration de la forme recombinante de l’activateur tissulaire du plasminogène (rt-PA) chez le patient victime d’un accident vasculaire cérébral (AVC) ischémique ne résulte pas uniquement de son action fibrinolytique mais aussi de sa capacité à augmenter le brain-derived neurotrophic factor (BDNF) dans le cerveau. Dans ce but, nous avons conduit une première étude visant à évaluer chez l’animal sain, l’effet du rt-PA sur les taux cérébraux de BDNF. Dans une seconde approche, nous avons étudié l’effet du rt-PA sur les taux sériques de BDNF chez le patient victime d’un AVC ischémique et chez l’animal soumis à une ischémie cérébrale focale. Le sang a été prélevé chez l’Homme à l’admission (J0), J1, J7 et J90 après l’AVC, et chez le Rat avant et après (1h, 4h et 24h) l’ischémie. Le BDNF a été mesuré dans le cerveau par technique de Western blot et dans le sang par technique ELISA. Dans les deux études le rt-PA (Actilyse®) a été administré sous forme d’un bolus suivi d’une perfusion d’une heure. La première étude montre que 1) le rt-PA augmente les taux de BDNF dans l’hippocampe, 2) le traitement par MK801 (un antagoniste des récepteurs NMDA) mais pas par l’acide tranexamique (un inhibiteur de la plasmine) annule l’effet du rt-PA sur les taux de BDNF. La deuxième étude met en évidence que 1) la récupération neurologique est meilleure chez les patients recevant le rt-PA, 2) le traitement par rt-PA augmente les taux sériques de BDNF à J1 et J7 chez l’Homme, mais ne modifie pas les taux sanguins de BDNF chez l’animal, 3) les taux de BDNF ne sont pas corrélés à la récupération neurologique mais sont inversement corrélés au score cardiovasculaire du patient. En conclusion, nos résultats suggèrent que le rt-PA peut exercer un effet protecteur extra-fibrinolytique en augmentant les taux de BDNFm par une potentialisation de l’activité glutamatergique. Même si le rt-PA induit une meilleure récupération neurologique et augmente les taux circulants de BDNF chez les patients victimes d’un AVC, l’absence de corrélation entre ces deux paramètres n’est pas en faveur de l’utilisation du BDNF circulant comme un marqueur prédictif de récupération neurologique, mais pourrait être un reflet de la capacité de l’endothélium à sécréter le BDNF
Our objective was to test the hypothesis that the beneficial effect of the administration of the recombinant form of tissue plasminogen activator (rt-PA) in ischemic stroke patient not only results from its fibrinolytic activity but also from its ability to increase brain-derived neurotrophic factor (BDNF) in the brain. To this end, we conducted an initial study to evaluate the effect of rt-PA on brain BDNF levels in healthy animals. In a second study, we investigated the effect of rt-PA on serum BDNF levels in ischemic stroke patients and in animals subjected to permanent focal cerebral ischemia. Blood samples were obtained from patient on admission (D0), D1, D7 and D90 after stroke and in rats before and after (1h, 4h and 24h) ischemia. BDNF was measured in the brain by Western blot and in the blood by ELISA. In both studies, the rt-PA (Actilyse®) was administered as a bolus followed by an infusion of one hour. The first study evidences that 1) rt-PA increases the BDNF levels in the hippocampus, 2) treatment with MK801 (a NMDA receptor antagonist) but not with tranexamic acid (a plasmin inhibitor) canceled the effect of rt-PA on BDNF levels. The second study exhibits that 1) neurological recovery was higher in the patients receiving rt-PA, 2) treatment with rt-PA increases serum BDNF at D1 and D7 in patients, but does not change the blood BDNF levels in animals, 3) BDNF levels are not correlated with neurological recovery but are inversely correlated to the patient cardiovascular score. In conclusion, our results suggest that rt-PA may have a protective extra-fibrinolytic effect by increasing in BDNF levels through a potentiation of glutamatergic pathway. Although rt-PA induces a better neurological recovery and increases circulating BDNF levels in stroke patients, the lack of correlation between these two parameters is not in favor of using circulating BDNF as a predictive marker of neurological recovery, but could be a reflect of the endothelium ability to synthesize BDNF
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Chan, Meanne. "Implicit measures of early-life family conditions : relationships to psychosocial characteristics and cardiovascular disease risk in adulthood". Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36745.

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An implicit measure of early-life family conditions was created to help address potential biases in responses to self-reported questionnaires of early-life family environments. We investigated whether a computerized affect attribution paradigm designed to capture implicit, affective responses (anger, fear, warmth) regarding early-life family environments was a) stable over time, b) associated with self-reports of childhood family environments, c) able to predict adult psychosocial profiles (perceived social support, heightened vigilance), and d) able to predict adult cardiovascular risk (blood pressure) either alone or in conjunction with a measure of early-life socioeconomic status. Two studies were conducted to examine reliability and validity of the affect attribution paradigm (Study 1, N = 94) and associated adult psychosocial outcomes and cardiovascular risk (Study 2, N = 122). Responses on the affect attribution paradigm showed significant correlations over a 6-month period, and were moderately associated with self-reports of childhood family environments. Greater attributed negative affect about early-life family conditions predicted lower levels of current perceived social support and heightened vigilance in adulthood. Attributed negative affect also interacted with early-life socioeconomic status to marginally predict resting systolic blood pressure, such that those individuals high in early-life SES but who had implicit negative affect attributed to early-life family conditions had SBP levels that were as high as individuals low in early-life SES. Implicit measures of early-life family conditions are a useful approach for assessing the psychosocial nature of early-life environments and linking them to adult psychosocial and physiological health profiles.
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Höglund, Niklas. "Atrial fibrillation : treatment, associated conditions and quantification of symptoms". Doctoral thesis, Umeå universitet, Kardiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-138378.

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Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. There is a need for new pharmacological treatment strategies since the current antiarrhythmic drugs have a modest efficacy and may have severe side effects. Cardioversion (CV) of AF offers an opportunity to study related conditions in sinus rhythm (SR) and during AF. Since catheter ablation of AF is a symptomatic treatment, it is important to have tools for measurement of arrhythmia-related symptoms. Aims: To evaluate the effect of atorvastatin on maintaining SR after CV of persistent AF. To assess if highsensitivity C-reactive protein (hsCRP) predicts the recurrence of AF after CV in a population randomized to treatment with either atorvastatin or placebo. To quantify the symptomatic effect of left atrial catheter ablation of AF. To assess if the restoration of SR by CV, in a population with persistent AF, affects sleep apnea. Methods: Paper I: A total of 234 patients were randomized to treatment with either high dose atorvastatin or placebo prior to CV. Paper II: In a pre-specified substudy which included 128 of the patients in study I, hsCRP was analyzed before and after CV. Paper III: Umea 22 Arrhythmia Questions (U22) is a questionnaire that quantifies paroxysmal tachycardia symptoms. A total of 105 patients underwent first-time pulmonary vein isolation and answered U22 forms at baseline and follow-up 304 (SD 121) days after ablation. Paper IV: Polysomnography was performed before and after CV in 23 patients with persistent AF scheduled for elective CV. Results: Paper I: An intention-to-treat analysis with the available data, by randomization group, showed that 57 (51%) in the atorvastatin group and 47 (42%) in the placebo group were in SR 30 days after CV (OR 1.44, 95%CI 0.85–2.44, P=0.18). Paper II: HsCRP did not significantly predict recurrence of AF at 30 days. However, after adjusting for treatment with atorvastatin, hsCRP predicted the recurrence of AF (OR 1.14, 95% CI 1.01–1.27). Six months after CV, hsCRP at randomization predicted recurrence of AF in both univariate analysis (OR 1.30, 95% CI 1.06–1.60) and in multivariate logistic regression analysis (OR 1.33, 95% CI 1.06– 1.67). Paper III: The U22 scores for well-being, arrhythmia as cause for impaired well-being, derived timeaspect score for arrhythmia, and discomfort during attack detected relevant improvements of symptoms after the ablation. U22 showed larger improvement in patients undergoing only one procedure than in patients who later underwent repeated interventions. Paper IV: Obstructive sleep apnea occurred in 17/23 patients (74%), and central sleep apnea in 6/23 patients (26%). Five patients had both obstructive and central sleep apnea. SR at follow-up was achieved in 16 patients. The obstructive apnea-hypopnea index, central apneahypopnea index, and the number of patients with obstructive or central sleep apnea did not differ before and after restoration of SR. Conclusions: Atorvastatin is not a treatment option with regards to maintaining SR after CV in patients with persistent AF. HsCRP was associated with AF recurrence 1 and 6 months after successful CV of persistent AF. U22 quantifies the symptomatic improvement after AF ablation with adequate internal consistency and construct validity. Both obstructive and central sleep apneas are highly prevalent in patients with persistent AF. Obstructive sleep apneas are unaffected by the CV of AF to SR.
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Konrad, David. "Cardiac function in experimental septic and non-septic conditions with special reference to the endothelin system /". Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-984-X/.

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Libri sul tema "Cardiovascular conditions"

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Kaski, Juan Carlos, Michael Papadakis e Hariharan Raju, a cura di. Investigating and Managing Common Cardiovascular Conditions. London: Springer London, 2015. http://dx.doi.org/10.1007/978-1-4471-6696-2.

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Pressman, Alan H. Treating hypertension and other cardiovascular conditions. New York: Berkely Books, 1997.

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1930-, Harlan William R., e National Center for Health Statistics (U.S.), a cura di. Health care utilization and costs of adult cardiovascular conditions, United States, 1980. Hyattsville, Md: U.S. Dept. of Health and Human Services, Public Health Service, Center for Disease Control, National Center for Health Statistics, 1989.

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M, MacKnight John, e Miller Mark D, a cura di. Training room management of medical conditions. Philadelphia: Saunders, 2005.

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A, Kerr Eve, Rand Corporation e United States. Agency for Healthcare Research and Quality., a cura di. Quality of care for cardiopulmonary conditions: A review of the literature and quality indicators. Santa Monica, CA: Rand Health, 2000.

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Hashefi, Mandana. PET/CT applications in non-neoplastic conditions. A cura di New York Academy of Sciences. Boston, Mass: Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2011.

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World Health Organization (WHO). A race against time: The challenge of cardiovascular disease in developing economies. New York, NY: Trustees of Columbia University in the City of New York, 2004.

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Hans, Hoffmeister, a cura di. Sozialer Status und Gesundheit: Nationaler Gesundheits-Survey, 1984-1986 : Unterschiede in der Verteilung von Herz-Kreislauf-Krankheiten und ihrer Risikofaktoren in der Bevölkerung der Bundesrepublik Deutschland nach Schichten und Gruppen. München: MMV Medizin Verlag, 1992.

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Black, Jessica K. Eating your way back to health: A guide to inflammatory cooking - reduce inflammation to help heal cardiovascular disease, arthritis, fibromyalgia, diabetes, allergies, and many more conditions. McMinnville, Ore: A Family Healing Center, 2004.

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Rath, Matthias. Why animals don't get heart attacks-- but people do!: The discovery that will eradicate heart disease : the natural prevention of heart attacks, strokes, high blood pressure, diabetes, high cholesterol and many other cardiovascular conditions. 4a ed. Fremont, CA: MR Pub., 2003.

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Capitoli di libri sul tema "Cardiovascular conditions"

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Ramzan, Pieter H. L. "Cardiovascular Conditions". In The Racehorse, 313–18. 2a ed. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003003847-13.

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Rehberg, Robb S., e Joelle Stabile Rehberg. "Cardiovascular Conditions". In Cram Session in General Medical Conditions, 1–18. New York: Routledge, 2024. http://dx.doi.org/10.4324/9781003523406-1.

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Chung, Frank, e Lori Roy. "Cardiovascular Conditions". In Cardiopulmonary Physical Therapy, 53–76. 2a ed. New York: Routledge, 2024. http://dx.doi.org/10.4324/9781003522829-4.

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Hupp, Wendy S. "Cardiovascular Diseases". In The ADA Practical Guide to Patients with Medical Conditions, 25–42. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2015. http://dx.doi.org/10.1002/9781119121039.ch2.

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Apple, Fred S., e David A. Morrow. "Cardiac Troponin in Conditions Other Than Acute Coronary Syndromes". In Cardiovascular Biomarkers, 139–59. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59745-051-5_10.

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Robb, Laura. "Genetic Counseling in Cardiovascular Conditions". In Clinical Approach to Sudden Cardiac Death Syndromes, 327–35. London: Springer London, 2009. http://dx.doi.org/10.1007/978-1-84882-927-5_26.

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Wenk, Jonathan F., Choon-Sik Jhun, Zhihong Zhang, Kay Sun, Mike Burger, Dan Einstein, Mark Ratcliffe e Julius M. Guccione. "In Vivo Left Ventricular Geometry and Boundary Conditions". In Computational Cardiovascular Mechanics, 3–21. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-1-4419-0730-1_1.

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Arslanian-Engoren, Cynthia, Rebecca Gary, Christa Irwin e Wenhui Zhang. "Chronic and Other Conditions That Increase CVD Risk". In Preventive Cardiovascular Nursing, 181–227. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-53705-9_7.

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Seward, Katelyn A., Khadijah Hussain e Bruce J. Kimura. "Headache and the Cardiovascular Patient". In Comorbid Conditions in the Treatment of Headache, 67–90. Boca Raton: CRC Press, 2024. https://doi.org/10.1201/b23330-5.

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Carr-White, Gerry, e Robert Leema. "Multi-Disciplinary Management of Inherited Cardiovascular Conditions". In Cardiovascular Genetics and Genomics, 817–38. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-66114-8_29.

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Atti di convegni sul tema "Cardiovascular conditions"

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Nissanka, Hashith, Sajini Wijayasundara, Jude Rajarathne, Sahan Vidanagamage, Didula Thanaweera Arachchi e Pradeep K. W. Abeygunawardhana. "VascularVision: Mixed Reality Based Teaching and Learning Environment for Cardiovascular Conditions". In 2024 6th International Conference on Advancements in Computing (ICAC), 450–55. IEEE, 2024. https://doi.org/10.1109/icac64487.2024.10851104.

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Barquero, Alberto, Pablo Armañac-Julián, Raquel Bailón, Jesus Lazaro, Eduardo Gil e David Hernando. "Validating a PPG Device for Estimating Heart Rate in Various Activity Conditions". In 2024 13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO), 1–2. IEEE, 2024. http://dx.doi.org/10.1109/esgco63003.2024.10766973.

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Rus, Madalina, Silvia Veresiu, Elena Mereuta, Valentin Amortila e George Balasoiu. "EVALUATING THE IMPACT OF AUTOMOBILE POLLUTION ON THE HEALTH OF THE ROMANIAN POPULATION THROUGH STATISTICAL METHODS". In 24th SGEM International Multidisciplinary Scientific GeoConference 24, 395–402. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024/4.1/s19.52.

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This research aims to conduct a descriptive statistical analysis to identify the statistical correlation between categories of new and second-hand vehicles registered for circulation in Romania and various health conditions associated with atmospheric pollution. Currently, a significant challenge for the global community lies in mitigating the impact of atmospheric pollution, considered a crucial factor both in terms of global climate change and its impact on public health. One major source of atmospheric pollution stems from emissions generated by internal combustion engines in the transportation sector. According to studies conducted by the European Environment Agency, approximately 70% of total greenhouse gas emissions originate from road transport, surpassing the European average in Romania due to the substantial number of second-hand vehicles registered and in circulation. Emissions resulting from petroleum-based fuels are associated with the onset of cardiovascular and respiratory system conditions. Through this descriptive statistical analysis, grounded in the Pearson correlation coefficient, we aim to emphasize the existing relationship between the number of vehicles and the prevalence of respiratory and cardiovascular system conditions, etc., with the goal of drawing attention to the implications of auto pollution. To conduct this study, we utilized data available on the National Institute of Statistics (INSSE) portal, covering a 21-year interval from January 2000 to December 2021.
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Rivera, Jason, Kelsey Rodriguez e Xiao-Hua Yu. "Cardiovascular Conditions Classification Using Adaptive Neuro-Fuzzy Inference System". In 2019 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE). IEEE, 2019. http://dx.doi.org/10.1109/fuzz-ieee.2019.8858896.

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Olatunji, Zainab Omotola, Susan Currie e Niall MacQuaide. "RWOP3 Cardiac fibroblasts modulate Ca2+signalling in cardiac myocytes under hyperglycaemic and hypertensive conditions". In Scottish Cardiovascular Forum – 27th annual meeting. BMJ Publishing Group Ltd and British Cardiovascular Society, 2024. http://dx.doi.org/10.1136/heartjnl-2024-scf.3.

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Reinhart-King, Cynthia A., Keigi Fujiwara e Michael R. King. "The Cardiovascular Microenvironment". In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30167.

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Endothelial cell response to the complex hemodynamic environment of the circulatory system is critical to the pathophysiological regulation of the cardiovascular system; however the mechanism by which this mechanical signal is transduced remains poorly understood. Recent in vivo evidence suggests that cells are capable of responding locally to shear stress, on the length scale of a single cell. Because of the complexity of the in vivo environment, we have designed and characterized an in vitro microchannel chamber with well-defined rheological conditions. This system is being used to investigate endothelial cell signaling response to shear stress, thereby bridging the gap between in vivo and in vitro observations.
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Ahrens, Esben, Helge B. D. Sorensen, Henning Langberg, Karsten Hoppe e Dorthe Bodholt Saadi. "Investigation of the Minimum Conditions for Reliable Estimation of Clinically Relevant HRV Measures - Introducing a Novel Approach to the Validation of HRV Measurement Systems". In International Congress on Cardiovascular Technologies. SCITEPRESS - Science and and Technology Publications, 2015. http://dx.doi.org/10.5220/0005608300300038.

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Kung, Ethan O., Andrea S. Les, Francisco R. Medina, Ryan B. Wicker, Michael V. McConnell e Charles A. Taylor. "In Vitro Validation of Finite Element Model of AAA Hemodynamics Incorporating Realistic Outflow Boundary Conditions". In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19304.

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Numerical methods have become a powerful tool to quantify hemodynamic forces in the cardiovascular system. Studying these forces enables us to understand cardiovascular disease mechanisms, as well as better evaluate and design cardiovascular medical devices. However, much work remains to validate numerical methods against experimental data. Vignon-Clementel and colleagues have shown that the boundary conditions (BCs) prescribed at the outlets of numerical domains dramatically influence the flow and pressure computational results [1]. While many in-vitro studies have implemented simple BCs to allow for acceptable validations of numerical methods, none has implemented BCs that provide physiologically realistic flows and pressures.
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Umnyagina, I. A. "METHODOLOGICAL APPROACHES TO THE EARLY DIAGNOSIS OF CARDIOVASCULAR PATHOLOGY IN WORKERS IN HARMFUL WORKING CONDITIONS". In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-519-522.

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Abstract. The aim of the study is to assess the informativeness of a number of clinical, functional, laboratory parameters as indicators of cardiovascular pathology in workers exposed to harmful industrial factors during mandatory periodic medical examinations, to identify some pathogenetic mechanisms of the formation of the risk of cardiovascular diseases (CVD). The experienced workers (n=310) of the metallurgical enterprise of the Nizhny Novgorod region were examined. The sphygmometry indicators, the content of endothelin-1, nitric oxide, lipid profile, ox-LDL, and the levels of IgG-class autoantibodies (aAT) to the antigens of the myocardial and vascular wall structures were evaluated in addition to regulated researches. The complex approach made it possible to more fully identify violations of the cardiovascular system, and elucidate some of the pathogenetic mechanisms of CVD development in workers in hazardous working conditions.
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Ishbulatov, Yurii M., Anatoly S. Karavaev, Vladimir I. Ponomarenko, Mikhail D. Prokhorov, Anton R. Kiselev e Boris P. Bezruchko. "Mathematical modeling of nonlinear dynamics of the cardiovascular system under different physiological conditions". In 2021 5th Scientific School Dynamics of Complex Networks and their Applications (DCNA). IEEE, 2021. http://dx.doi.org/10.1109/dcna53427.2021.9586751.

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Rapporti di organizzazioni sul tema "Cardiovascular conditions"

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Gontar, I. P., O. A. Rusanova, A. S. Trofimenko, O. I. Emelyanova, L. A. Maslakova e N. Emelyanov. CARDIOVASCULAR CONDITIONS IN PATIENTS WITH SYSTEMIC SCLERODERMA THAT ARE ASSOCIATED WITH HUMORAL IMMUNITY IMPAIRMENT TO ELASTIN AND ELSTASE. Планета, 2018. http://dx.doi.org/10.18411/978-5-907109-24-7-2018-xxxiv-54-55.

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Wang, Zhen, Alaa Al Nofal, Meera Shah, Sara L. Bonnes, Samer Saadi, Alzhraa S. Abbas, Magdoleen H. Farah et al. Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition. Agency for Healthcare Research and Quality (AHRQ), marzo 2025. https://doi.org/10.23970/ahrqepcsr_carbcardio.

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Background. Epidemiological studies have shown inconsistent findings regarding the effect of dietary digestible carbohydrate intake on the risk of cardiovascular disease and type 2 diabetes (T2D). Synthesis of such evidence is important for determining the Dietary Reference Intakes (DRI) for carbohydrates, which can have consequences on incidence and morbidity of chronic conditions. Methods. Two systematic reviews were conducted, one addressing cardiovascular outcomes and the second addressing incidence of T2D, body weight, and composition. We searched several databases from January 1, 2000, to July 19, 2024, and searched gray literature. Eligible studies evaluated the outcomes of interest in healthy individuals over 2 years old and isolated the effect of digestible carbohydrate intake from other macronutrients in grams per day or percent of total energy intake. Random-effects dose-response meta-analyses were conducted when feasible. Results. The systematic review on cardiovascular outcome included 21 prospective cohort studies with 1,277,621 participants. The majority of the studies reported inadequate confounding adjustment (73%) and were deemed to have serious risks of bias (80%). No eligible studies evaluated children under 18 years. The association between digestible carbohydrate intake and cardiovascular outcomes was nonlinear and was supported by low strength of evidence. When carbohydrate intake was analyzed as the percentage of total energy intake, the risk of incident cardiovascular disease significantly increased when carbohydrate intake exceeded 65 percent total energy intake, compared with the carbohydrate intake reference level of 50 percent total energy intake. The lowest risk was at a carbohydrate intake level of 50 percent total energy intake. The risk of incident coronary heart disease increased starting at a carbohydrate intake level of 45 percent total energy intake. When carbohydrate intake was analyzed as grams per day, the risk of incident cardiovascular disease significantly increased when carbohydrate intake exceeded 300 grams per day, compared with a reference level of 300 grams per day. The lowest risk was at a carbohydrate intake level of 250 grams per day. The risk of incident coronary heart disease increased starting at 250 grams per day of carbohydrates. The nonlinear relationships were overall similar based on sex or geographic location but with variable intake range associated with the lowest risk. Higher carbohydrate intake was associated with lower levels of high-density lipoprotein-cholesterol and higher levels of triglycerides. The systematic review on diabetes and body composition included 17 studies with 497,941 participants. The majority of the studies reported inadequate confounding adjustment (79%) and were deemed to have serious risks of bias (92%). No eligible studies evaluated children under 18 years. The association between carbohydrate intake and incident T2D was nonlinear and was supported by low strength of evidence. Analyzing carbohydrate intake as a percentage of total energy intake showed a gradual reduction in the risk of incident T2D up to 45 percent total energy intake. The risk then plateaued between 45 percent and 55 percent total energy intake before rising with higher carbohydrate intake levels. Similarly, analyzing carbohydrate intake in grams per day revealed a gradually reduced risk up to 270 grams per day, followed by a plateau between 270–350 grams per day and increased risk after 350 grams per day. The evidence was insufficient to determine an association between carbohydrate intake and weight or body composition. The nonlinear relationships were overall similar based on sex but with variable intake range associated with the lowest risk. Very few studies evaluated intermediate outcomes. Conclusion. Dose-response meta-analyses suggest a nonlinear relationship between the intake of digestible carbohydrates and cardiovascular disease and incident T2D. These associations appear to be U-shaped and suggest certain ranges of carbohydrate intake that were associated with the lowest risk. Such ranges can help in establishing future DRI for carbohydrates, which can have important consequences on incidence and morbidity of chronic conditions and public health.
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Hernández-Mitre, María Patricia, Susan C. Morpeth, Balasubramanian Venkatesh, Thomas E. Hills, Joshua Davis, Robert K. Mahar, Grace McPhee et al. TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of nafamostat and camostat mesylate randomised clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, febbraio 2023. http://dx.doi.org/10.37766/inplasy2023.2.0120.

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Review question / Objective: The primary objective of the systematic review and meta-analysis is to determine whether TMPRSS2 inhibition with nafamostat or camostat mesylate is associated with a reduced risk of 30-day all-cause mortality in hospitalised and non-hospitalised adults with COVID-19. Condition being studied: Coronavirus disease 2019 (COVID-19). COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Most people infected with the virus will experience mild to moderate respiratory illness and recover without requiring special treatment. However, some will become seriously ill and require medical attention. Older people and those with underlying medical conditions like cardiovascular disease, diabetes, chronic respiratory disease, or cancer are more likely to develop serious illness. Anyone can get sick with COVID-19 and become seriously ill or die at any age.
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van den Berg, Gerard J., Gabriele Doblhammer-Reiter e Kaare Christensen. Being born under adverse economic conditions leads to a higher cardiovascular mortality rate later in life: evidence based on individuals born at different stages of the business cycle. Rostock: Max Planck Institute for Demographic Research, ottobre 2008. http://dx.doi.org/10.4054/mpidr-wp-2008-023.

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Zyriax, Birgit-Christiane, e Eberhard Windler. Lifestyle changes at midlife to prevent cardiovascular disease: a systematic review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, aprile 2022. http://dx.doi.org/10.37766/inplasy2022.4.0061.

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Review question / Objective: What kind of evidence-based diet and physical activity should or can be recommended to adults in order to reduce their cardiovascular risk. Condition being studied: Cardiovascular disease. Eligibility criteria: Publications will be extracted independently by two researchers according to defined search string and get color coded as agreed on: Yellow: studies and RCTs of the association of nutrients, physical activity and cardiovascular outcomes for discussion. Green: meta-analysis of studies and RCTs of the association of nutrients, physical activity and cardiovascular outcomes. Green subgroup AMSTAR-2: meta-analysis of studies and RCTs of the association of food-patterns and cardiovascular outcomes. The AMSTAR-2 checklist will be used for evaluating the methodological quality of these studies.
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Ferdosian, Hengameh, Hadi Zamanian, Sayed Ali Emami, Elahe Sedighi, Mina Moridi e Maryam Doustmehraban. Application of artificial intelligence in prediction of cardiovascular complications in patients with diabetes mellitus type 2: A protocol of systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, ottobre 2021. http://dx.doi.org/10.37766/inplasy2021.10.0076.

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Review question / Objective: The aim of this systematic review is to evaluate AI-based models in identifying predictors of cardiovascular events and risk predtion in patients with diabetes mellitus type2. Condition being studied: T2DM patients have an increased risk of macrovascular and microvascular complications, lead to decreased quality of life and mortality. Considering the significance of cardiovascular complications in these patients, prediction of such events would be important. Different traditional statistical methods(such as regression) and new AI-besed algorithms are used to predict these complications in diabetic patients.
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Zhang, Mingzhu, Wujisiguleng Bao, Luying Sun, Zhi Yao e Xiyao Li. Efficacy and safety of finerenone in chronic kidney disease associated with type 2 diabetes: meta-analysis of randomized clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, marzo 2022. http://dx.doi.org/10.37766/inplasy2022.3.0020.

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Review question / Objective: To assess the beneficial effect and safety of finerenone for patients with chronic kidney disease associated with type 2 diabetes. Condition being studied: Chronic kidney disease (CKD) is a major contributor to morbidity and mortality from non-communicable diseases, affecting almost 700 million people worldwide. Approximately 40% of patients with diabetes have CKD, which exposes them to a 3-fold higher risk of cardiovascular death versus those with T2D alone. Strategies to protect the kidneys of patients with CKD and T2D may reduce their risk of cardiovascular events. Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced composite kidney and cardiovascular outcome in trials involving patients with chronic kidney disease. Recently, quite a few clinical studies have been conducted to compare finerenone and placebo. Our meta-analysis aimed to investigate the efficacy and safety of finerenone in chronic kidney disease associated with T2D. 1st author* - Mingzhu Zhang and Wujisiguleng Bao contributed equally to this study.
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Liu, Gejing, Man Ren, Yingshi Du, Xinni Xu, Ruoyu Zhao, Yu Wu, Yongming Liu e Liang Qi. A meta-analysis of Effect of thyroid hormone replacement therapy on the Cardiac diastolic function in Patients with Subclinical Hypothyroidism. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, febbraio 2023. http://dx.doi.org/10.37766/inplasy2023.2.0083.

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Review question / Objective: P:Subclinical Hypothyroidism(Age over 18); I:thyroid hormone replacement therapy; C:baseline(before-after study in the same patient); O:Cardiac diastolic function measurement by echocardiography. Condition being studied: Subclinical hypothyroidism is associated with anomalies left ventricular diastolic functions, however, there are still disputes about whether to use levothyroxine for treatment. This meta-analysis aimed to determine whether levothyroxine (LT4), commonly used to treat hypothyroidism, affects cardiovascular indices in SCH patients as measured by echocardiography.
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Brosh, Arieh, David Robertshaw, Yoav Aharoni, Zvi Holzer, Mario Gutman e Amichai Arieli. Estimation of Energy Expenditure of Free Living and Growing Domesticated Ruminants by Heart Rate Measurement. United States Department of Agriculture, aprile 2002. http://dx.doi.org/10.32747/2002.7580685.bard.

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Research objectives were: 1) To study the effect of diet energy density, level of exercise, thermal conditions and reproductive state on cardiovascular function as it relates to oxygen (O2) mobilization. 2) To validate the use of heart rate (HR) to predict energy expenditure (EE) of ruminants, by measuring and calculating the energy balance components at different productive and reproductive states. 3) To validate the use of HR to identify changes in the metabolizable energy (ME) and ME intake (MEI) of grazing ruminants. Background: The development of an effective method for the measurement of EE is essential for understanding the management of both grazing and confined feedlot animals. The use of HR as a method of estimating EE in free-ranging large ruminants has been limited by the availability of suitable field monitoring equipment and by the absence of empirical understanding of the relationship between cardiac function and metabolic rate. Recent developments in microelectronics provide a good opportunity to use small HR devices to monitor free-range animals. The estimation of O2 uptake (VO2) of animals from their HR has to be based upon a consistent relationship between HR and VO2. The question as to whether, or to what extent, feeding level, environmental conditions and reproductive state affect such a relationship is still unanswered. Studies on the basic physiology of O2 mobilization (in USA) and field and feedlot-based investigations (in Israel) covered a , variety of conditions in order to investigate the possibilities of using HR to estimate EE. In USA the physiological studies conducted using animals with implanted flow probes, show that: I) although stroke volume decreases during intense exercise, VO2 per one heart beat per kgBW0.75 (O2 Pulse, O2P) actually increases and measurement of EE by HR and constant O2P may underestimate VO2unless the slope of the regression relating to heart rate and VO2 is also determined, 2) alterations in VO2 associated with the level of feeding and the effects of feeding itself have no effect on O2P, 3) both pregnancy and lactation may increase blood volume, especially lactation; but they have no effect on O2P, 4) ambient temperature in the range of 15 to 25°C in the resting animal has no effect on O2P, and 5) severe heat stress, induced by exercise, elevates body temperature to a sufficient extent that 14% of cardiac output may be required to dissipate the heat generated by exercise rather than for O2 transport. However, this is an unusual situation and its affect on EE estimation in a freely grazing animal, especially when heart rate is monitored over several days, is minor. In Israel three experiments were carried out in the hot summer to define changes in O2P attributable to changes in the time of day or In the heat load. The animals used were lambs and young calves in the growing phase and highly yielding dairy cows. In the growing animals the time of day, or the heat load, affected HR and VO2, but had no effect on O2P. On the other hand, the O2P measured in lactating cows was affected by the heat load; this is similar to the finding in the USA study of sheep. Energy balance trials were conducted to compare MEI recovery by the retained energy (RE) and by EE as measured by HR and O2P. The trial hypothesis was that if HR reliably estimated EE, the MEI proportion to (EE+RE) would not be significantly different from 1.0. Beef cows along a year of their reproductive cycle and growing lambs were used. The MEI recoveries of both trials were not significantly different from 1.0, 1.062+0.026 and 0.957+0.024 respectively. The cows' reproductive state did not affect the O2P, which is similar to the finding in the USA study. Pasture ME content and animal variables such as HR, VO2, O2P and EE of cows on grazing and in confinement were measured throughout three years under twenty-nine combinations of herbage quality and cows' reproductive state. In twelve grazing states, individual faecal output (FO) was measured and MEI was calculated. Regression analyses of the EE and RE dependent on MEI were highly significant (P<0.001). The predicted values of EE at zero intake (78 kcal/kgBW0.75), were similar to those estimated by NRC (1984). The EE at maintenance condition of the grazing cows (EE=MEI, 125 kcal/kgBW0.75) which are in the range of 96.1 to 125.5 as presented by NRC (1996 pp 6-7) for beef cows. Average daily HR and EE were significantly increased by lactation, P<0.001 and P<0.02 respectively. Grazing ME significantly increased HR and EE, P<0.001 and P<0.00l respectively. In contradiction to the finding in confined ewes and cows, the O2P of the grazing cows was significantly affected by the combined treatments (P<0.00l ); this effect was significantly related to the diet ME (P<0.00l ) and consequently to the MEI (P<0.03). Grazing significantly increased O2P compared to confinement. So, when EE of grazing animals during a certain season of the year is estimated using the HR method, the O2P must be re measured whenever grazing ME changes. A high correlation (R2>0.96) of group average EE and of HR dependency on MEI was also found in confined cows, which were fed six different diets and in growing lambs on three diets. In conclusion, the studies conducted in USA and in Israel investigated in depth the physiological mechanisms of cardiovascular and O2 mobilization, and went on to investigate a wide variety of ruminant species, ages, reproductive states, diets ME, time of intake and time of day, and compared these variables under grazing and confinement conditions. From these combined studies we can conclude that EE can be determined from HR measurements during several days, multiplied by O2P measured over a short period of time (10-15 min). The study showed that RE could be determined during the growing phase without slaughtering. In the near future the development microelectronic devices will enable wide use of the HR method to determine EE and energy balance. It will open new scopes of physiological and agricultural research with minimizes strain on animals. The method also has a high potential as a tool for herd management.
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Sosa Munguía, Paulina del Carmen, Verónica Ajelet Vargaz Guadarrama, Marcial Sánchez Tecuatl, Mario Garcia Carrasco, Francesco Moccia e Roberto Berra-Romani. Diabetes mellitus alters intracellular calcium homeostasis in vascular endothelial cells: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maggio 2022. http://dx.doi.org/10.37766/inplasy2022.5.0104.

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Review question / Objective: What are the effects of diabetes mellitus on the calcium homeostasis in vascular endothelial cells? -To describe the effects of diabetes on the mechanisms that regulate intracellular calcium; -To describe other molecules/mechanisms that alters intracellular Ca2+ homeostasis. Condition being studied: Diabetes mellitus is a pathology with a high incidence in the population, characterized by an increase in blood glucose. People with diabetes are 2-4 times more likely to suffer from a cardiovascular complication, such as total or partial loss of sight, myocardial infarction, kidney failure, among others. Cardiovascular complications have been reported to derive from dysfunction of endothelial cells, which have important functions in blood vessels. In order to understand the etiology of this poor function of endothelial cells, it is necessary to study the molecular mechanisms involved in these functions, to identify the effects of diabetes and thus, develop new research that will mitigate the effects of this pathology.
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