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1

Meena, Jagram, Harish Chandra, and Sudhir G. Warkar. "Carboxymethyl Tamarind Kernel Gum /ZnO- Biocomposite: As an Antifungal and Hazardous Metal Removal Agent." Journal of New Materials for Electrochemical Systems 25, no. 3 (2022): 206–13. http://dx.doi.org/10.14447/jnmes.v25i3.a08.

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Abstract (sommario):
ZnO nanoparticles (ZnO NPs) were in situ mixed with carboxymethyl tamarind kernel gum to generate the new biocomposite. High-resolution transmission electron microscopy (HR-TEM), field emission scanning electron microscopy (FE-SEM), Fourier transform infrared (FTIR), x-ray diffraction analysis (XRD), and dynamic light scattering (DLS)were used to characterize the CMTKG/ZnO nanocomposites. Numerous characterizations were utilized to prove that ZnO NPs had been integrated into the biopolymer matrix. The standard size of the CMTKG/ZnO nanocomposites was developed to be greater than 32–40 nm using
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2

Meena, Jagram, Sudhir G. Warkar, and Devendra Kumar Verma. "Carboxymethyl Tamarind Kernel Gum Nanoparticles; As an Antioxidant Activity." Journal of New Materials for Electrochemical Systems 26, no. 3 (2023): 145–50. http://dx.doi.org/10.14447/jnmes.v26i3.a01.

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The incorporation of biopolymer nanoparticles with potential antioxidant properties into biomaterials for human health care is significant. The current study focuses on nanoparticles carboxymethyl tamarind kernel gum (CMTKG) composite materials because of their potential applications. The co-precipitation method was used to create carboxymethyl tamarind kernel gum nanoparticles (CMTKG-NPs). This technique was used for the first time to create carboxymethyl tamarind kernel gum nanoparticles. The strength of nanoparticle conformation is reported to be influenced by co-precipitation and stirring
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3

Goleyjani Moghadam, Masoumeh, Zohreh Elahi, Mohamad Soveyzi, et al. "Expanding the Molecular Spectrum of HK1-Related Charcot-Marie-Tooth Disease, Type 4G; the First Report in Iran." Archives of Iranian Medicine 26, no. 5 (2023): 279–84. http://dx.doi.org/10.34172/aim.2023.43.

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Charcot-Marie-Tooth disease type 4G (CMT4G) was first reported in Balkan Gypsies as a myelinopathy starting with progressive distal lower limb weakness, followed by upper limb involvement and prominent distal sensory impairment later in the patient’s life. So far, CMT4G has been only reported in European Roma communities with two founder homozygous variants; g.9712G>C and g.11027G>A, located in the 5’-UTR of the HK1 gene. Here, we present the first Iranian CMT4G patient manifesting progressive distal lower limb weakness from 11 years of age and diagnosed with chronic demyelinating sensor
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Lhadon, Pema, Sonam Daker, Kesang Wangmo, and Kelzang. "Benefits of Communicative Method of Teaching Grammar in a Bhutanese Higher Secondary School: A Qualitative Study." Asian Journal of Education and Social Studies 43, no. 1 (2023): 20–31. http://dx.doi.org/10.9734/ajess/2023/v43i1932.

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The effective method to teach grammar to students has been a point of disputation between advocates for language acquisition and linguistics. The study investigated the benefits of the Communicative Method of Teaching Grammar (CMTG) in a Higher Secondary School under Thimphu Thromde. The study was based on the constructivist paradigm and adopted a qualitative case study research design. The study involved twelve students and three English teachers selected purposefully from a Higher Secondary School in Thimphu. The data was collected through one-on-one interviews, Focus group discussions (FGDs
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5

Scott, Brian, Andrew H. Baldwin, and Stephanie A. Yarwood. "Quantification of potential methane emissions associated with organic matter amendments following oxic-soil inundation." Biogeosciences 19, no. 4 (2022): 1151–64. http://dx.doi.org/10.5194/bg-19-1151-2022.

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Abstract. Methane (CH4) emissions are a potent contributor to global warming, and wetlands can be a significant CH4 source. In a microcosm study, we evaluated how the practice of amending soils with organic matter as part of wetland restoration projects may affect CH4 production potential. Organic amendments including hay, manure, biosolids, composted yard waste, and wood mulch were evaluated at three different levels. Using 1 L glass microcosms, we measured the production of biogenic gases over 60 d in two soils designated by texture: a sandy loam (SL) and a sandy clay loam (SCL). Fresh organ
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6

Sips, Patrick Y., Tomoya Irie, Lin Zou, et al. "Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression." American Journal of Physiology-Heart and Circulatory Physiology 304, no. 8 (2013): H1134—H1146. http://dx.doi.org/10.1152/ajpheart.00887.2012.

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Myocardial depression is an important contributor to morbidity and mortality in septic patients. Nitric oxide (NO) plays an important role in the development of septic cardiomyopathy, but also has protective effects. Recent evidence has indicated that NO exerts many of its downstream effects on the cardiovascular system via protein S-nitrosylation, which is negatively regulated by S-nitrosoglutathione reductase (GSNOR), an enzyme promoting denitrosylation. We tested the hypothesis that reducing cardiomyocyte S-nitrosylation by increasing GSNOR activity can improve myocardial dysfunction during
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7

Bachra, Yahya, Ayoub Grouli, Fouad Damiri, Mohammed Talbi, and Mohammed Berrada. "A Novel Superabsorbent Polymer from Crosslinked Carboxymethyl Tragacanth Gum with Glutaraldehyde: Synthesis, Characterization, and Swelling Properties." International Journal of Biomaterials 2021 (November 20, 2021): 1–14. http://dx.doi.org/10.1155/2021/5008833.

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Nowadays, current global environmental problems include measures to eliminate or reduce the negative impact of chemicals from petroleum sources and, therefore, the use of materials from natural resources is increasingly recommended. In this context, natural-based superabsorbent polymers derived from polypeptides and polysaccharides have undergone chemical and biochemical modifications to improve their ability to absorb and retain large amounts of liquids. In the present paper, a new process has been used to overcome the side effects of radical polymerization in the manufacture of conventional
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8

Baga, Margherita, Susanna Rizzi, Carlotta Spagnoli, Daniele Frattini, Francesco Pisani, and Carlo Fusco. "A Novel Family with Demyelinating Charcot–Marie–Tooth Disease Caused by a Mutation in the PMP2 Gene: A Case Series of Nine Patients and a Brief Review of the Literature." Children 10, no. 5 (2023): 901. http://dx.doi.org/10.3390/children10050901.

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Abstract (sommario):
Introduction: Charcot–Marie–Tooth (CMT) is a group of inherited peripheral neuropathies characterized by wide genotypic and phenotypic variability. The onset is typically in childhood, and the most frequent clinical manifestations are predominantly distal muscle weakness, hypoesthesia, foot deformity (pes cavus) and areflexia. In the long term, complications such as muscle-tendon retractions, extremity deformities, muscle atrophy and pain may occur. Among CMT1, demyelinating and autosomal dominant forms, CMT1G is determined by mutations in the PMP2 myelin protein. Results: Starting from the in
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9

Maina, John N., and Christopher Nathaniel. "A qualitative and quantitative study of the lung of an ostrich,Struthio camelus." Journal of Experimental Biology 204, no. 13 (2001): 2313–30. http://dx.doi.org/10.1242/jeb.204.13.2313.

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SUMMARYThe ostrich lung, with its lack of interparabronchial septa, the presence of very shallow atria and exceptional morphometric refinement, structurally resembles those of small, energetic flying birds, whereas it also displays features characteristic of the flightless ratites in which the neopulmo is relatively poorly developed and a segmentum accelerans may be generally lacking. The large size of the bronchial system of the ostrich may help explain the unique shifts in the airflow pathways that must occur from resting to panting breathing, explaining its insensitivity to acid–base imbala
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10

de Santi, Fabiane, Flávia L. Beltrame, Barry T. Hinton, Paulo S. Cerri, and Estela Sasso-Cerri. "Reduced levels of stromal sex hormone-binding globulin and androgen receptor dysfunction in the sperm storage region of the rat epididymis." Reproduction 155, no. 6 (2018): 467–79. http://dx.doi.org/10.1530/rep-18-0014.

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The cauda epididymidis is the major sperm storage region whose androgenic supply, essential for the sperm viability, is provided by the vasculature and is dependent upon testosterone diffusion through the stromal tissue to reach the epithelial cells. We have focused our efforts on examining the regulation of this important epididymal region by evaluating the impact of the androgen disrupter cimetidine on the epithelial–stromal androgenic microenvironment. Male rats received 100 mg/kg cimetidine (CMTG) or saline (CG) for 50 days, serum testosterone levels were measured and the epididymal cauda
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11

Ahamad Ansair, Niyaz, Jai Narayan Mishra, and Dhaneshwar Kumar Vishwakarma. "FORMULATION AND EVALUATION OF ANTIFUNGAL MICRO EMULSION-BASED GEL FOR TOPICAL DRUG DELIVERY USING MILLETIAPINNATA." International Journal of Advanced Research 10, no. 09 (2022): 680–94. http://dx.doi.org/10.21474/ijar01/15409.

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Firstly,we are study to formulate and test a topical gel containing of Itraconazole micro- emulsion (ITZ). The Formulation of micro emulsion researchis necessary to study before its thepreformulation study of micro emulsion of Itraconazole. To estimatethe maximal solubility of ITZ in oils, surfactants and co- surfactants were investigated to estimatefilling material potential. In reference to the micro- emulsion region, with Karanj oil as the oil phase, the use of surfactant as a Tween-80 and use as aDiamethyl Carbinol Or (IPA) as the Another surfactant to improve its performance, a pseudo- te
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12

de Santi, Fabiane, Isadora Dantas Lunardi, Flávia Luciana Beltrame, Paulo Sérgio Cerri, and Estela Sasso-Cerri. "Muscular atrophy, impaired epithelial autophagy and UCHL1 increase in androgen-deficient cauda epididymis." Reproduction 159, no. 6 (2020): 693–705. http://dx.doi.org/10.1530/rep-19-0462.

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Abstract (sommario):
In epididymis, cimetidine induces androgenic failure due to reduced sex hormone-binding globulin stromal levels and blockade of androgen receptor (AR) nuclear import. UCHL1, a hydrolase of ubiquitin-proteasome system (UPS), seems to play a role in autophagy and apoptotic pathway. However, the role of UPS and autophagy in epididymis has not been clarified. We evaluated UCHL1 and autophagy in epididymal cauda epithelium under androgenic deficiency induced by cimetidine, focusing on the interplay among these processes and apoptosis. The integrity of epididymal muscular layer was also evaluated. M
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13

Malaker, Kamal, Mustafa Zaidi, Mohamad Rida Franka, and Tawfik Al Yafi. "Concurrent Multi-Modality Treatment of Keloids (CMTK) Not Manageable by Conventional Postoperative Radiotherapy." International Journal of Clinical Medicine 04, no. 05 (2013): 273–81. http://dx.doi.org/10.4236/ijcm.2013.45048.

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14

Wang, Haiquan, Tao Zhu, Shuo Lei, Wenjing Yang, and Yu Wang. "CMTG: A Content-Based Mobile Tendency Geocast Routing Protocol in Urban Vehicular Networks." International Journal of Distributed Sensor Networks 11, no. 3 (2015): 163157. http://dx.doi.org/10.1155/2015/163157.

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15

Nelis, E. "Autosomal dominant axonal Charcot-Marie-Tooth disease type 2 (CMT2G) maps to chromosome 12q12-q13.3." Journal of Medical Genetics 41, no. 3 (2004): 193–97. http://dx.doi.org/10.1136/jmg.2003.012633.

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16

Guadalupe Rodríguez, Castillejos, León José Ramírez de, Vázquez Guadalupe Bustos, and Ruíz Octelina Castillo. "Properties of fish and beef restructured by MTG derived from Streptomyces mobaraensis grown in media based on enzymatic hydrolysates of sorghum." Czech Journal of Food Sciences 35, No. 6 (2017): 517–21. http://dx.doi.org/10.17221/422/2016-cjfs.

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The efficiency of microbial transglutaminase (MTG) obtained from Streptoverticillum ladakanaum fermentation of sorghum grain and DDGS hydrolysates (HMTG) in increasing the mechanical properties of restructured meat and fish products was evaluated in this study. Gels were obtained by adding HMTG or commercial MTG at 0.3 U/g, and controls lacked enzyme. All treatments were supplemented with 2.0% NaCl. The gels with enzyme showed a lower amount of expressible water, similar to those obtained with CMTG (6% for fish gels and 8% for beef gels). Texture values were also similar. The results showed th
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17

Biersbach, Raymond M. "Drug Treatment in New Jersey (and Elsewhere?): In Search of a Paradigm." Journal of Drug Education 15, no. 4 (1985): 387–96. http://dx.doi.org/10.2190/16eb-7fpt-cmtk-lxbx.

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In this article three points are made. First, a survey of drug treatment in New Jersey suggested that there was considerable conflict about how drug treatment should be conducted. Second, a case was made for developing paradigms or models of treatment as a guide for progress in treatment for addicts. Third, an example was given of a theoretical paradigm which tried to relate family therapy to the relief of self-esteem distress.
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18

Li, Wei-Hong, and Ning Yang. "Green fabrication of AuNPs/CMTKP/g-C3N4 nanocomposites with enhanced photocatalytic activity for the removal of nitric oxide under visible-light irradiation." Journal of Cleaner Production 256 (May 2020): 120257. http://dx.doi.org/10.1016/j.jclepro.2020.120257.

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19

Khushbu, Khushbu, and Sudhir G. Warkar. "Carboxymethyl Tamarind Kernel Gum based Controlled Drug Delivery Excipients: A Review." Journal of Engineering Research, March 15, 2022. http://dx.doi.org/10.36909/jer.icapie.15061.

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Abstract (sommario):
The Carboxymethyl Tamarind Kernel Gum (CMTKG) is a natural based polysaccharide which has been derived from the Tamarind kernel gum (TKG) through the carboxymethylation process. The chemical alteration of TKG into CMTKG has resulted in amplifying swelling capacity, in situ gelations, wide pH tolerance, high drug holding efficiency, stability, release kinetics, and hydrophilicity. Out of many application-based areas, it has extensively been used in the field of drug delivery systems via developing various forms like nanoparticles, composites, films, hydrogels, and pellets. This article is plann
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20

Kajal, Ramender Kumar, Priyanka Meena, and Sudhir G. Warkar. "Development and characterization of pH-responsive CMTKG/PAM/PEG hydrogel for oral administration of etophylline." Colloid and Polymer Science, August 7, 2023. http://dx.doi.org/10.1007/s00396-023-05152-8.

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21

Rani, Indu, Sudhir G. Warkar, and Anil Kumar. "Removal of Cationic Crystal Violet dye using Zeolite‐ Embedded Carboxymethyl Tamarind Kernel Gum (CMTKG) based Hydrogel Adsorbents." ChemistrySelect 8, no. 29 (2023). http://dx.doi.org/10.1002/slct.202301434.

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AbstractIn this research paper, various formulations of zeolite‐loaded carboxymethyl tamarind kernel gum (CMTKG) based hydrogels were synthesized and utilized as a potential adsorbent for the removal of crystal violet (CV) dye. The swelling capacity of all the synthesized hydrogels was investigated and the composition of hydrogel which exhibited maximum swelling was used for the characterization and dye removal experiment. The CV dye was chosen as a model dye for the dye removal experiment. The structure of zeolite and zeolite embedded hydrogel was elucidated by XRD, FTIR, FE‐SEM, EDX and elem
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22

Rani, Indu, Sudhir G. Warkar, and Anil Kumar. "Nano ZnO embedded Poly (ethylene glycol) diacrylate cross-linked Carboxymethyl tamarind kernel gum (CMTKG) /Poly (sodium acrylate) composite Hydrogels for oral delivery of Ciprofloxacin drug and their antibacterial properties." Materials Today Communications, February 2023, 105635. http://dx.doi.org/10.1016/j.mtcomm.2023.105635.

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23

Rohlfing, Torsten. "User Guide to The Computational Morphometry Toolkit." Insight Journal, March 23, 2011. http://dx.doi.org/10.54294/ttdjo3.

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This guide is intended as a very brief introduction of the main tools in the Computational Morphometry Toolkit (CMTK), which is available in source code and as precompiled binaries from http://www.nitrc.org/projects/cmtk/. The target audience of this document are CMTK users, who might use this document as a reference to the most common processing tasks, and prospective users, who may find this information useful to determine whether CMTK provides functionality that they can use. We focus in particular on a simplified workflow for deformation morphometry studies based on magnetic resonance imag
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24

Verma, Amit, Neetu Sachan, and Anurag Verma. "Carboxymethylation of Karaya gum: application in gastroretentive drug delivery for sustained release of model drug." International Journal of Pharmaceutical Sciences and Drug Research, May 30, 2020, 300–306. http://dx.doi.org/10.25004/ijpsdr.2020.120314.

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Karaya gum (KG) is one of the least soluble of the gums. It does not dissolve in water to give a clear solution but instead absorbs water rapidly to form viscous colloidal sols. Carboxymethylation of Karaya gum is expected to improve its aqueous solubility and gelling behavior. Another objective of the research is to evaluate the potential of carboxymethylated Karaya gum (CMKG) as drug release modulator (in acidic dissolution medium) when combined with HPMC K15M based polymeric matrices bearing Propranolol HCl. In the present study, KG was carboxymethylated using Williamson Ether synthesis. FT
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Rohlfing, Torsten. "Structural MRI Unwarping Using CMTK." Insight Journal, May 30, 2013. http://dx.doi.org/10.54294/d0pwqi.

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This document describes the workflow for unwarping structural MR images, in particular T1-weighted SPGR and MP-RAGE scans, using reference scans of the Magphan(R) EMR051 Quantitative Imaging Phantom (a.k.a. ADNI Phantom) and the tools of the Computational Morphometry Toolkit (CMTK).
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Rohlfing, Torsten. "Unwarping Echo Planar Images Using CMTK." Insight Journal, October 1, 2012. http://dx.doi.org/10.54294/qffl03.

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This document describes the workflow for unwarping echo planar MR images (EPI), in particular diffusion-weighted images, using an acquisition method with reversed phase encoding and the tools of the Computational Morphometry Toolkit (CMTK). This technique requires an additional acquisition (additional b=0 image for diffusion imaging) with reversed phase encoding direction, but no field map. Simple 6-direction diffusion data are provided with this article for demonstration.
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27

Kanwal, Sumaira, Yu JIn Choi, Si On Lim, et al. "Novel homozygous mutations in Pakistani families with Charcot–Marie–Tooth disease." BMC Medical Genomics 14, no. 1 (2021). http://dx.doi.org/10.1186/s12920-021-01019-5.

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Abstract Background Charcot–Marie–Tooth disease (CMT) is a group of genetically and clinically heterogeneous peripheral nervous system disorders. Few studies have identified genetic causes of CMT in the Pakistani patients. Methods This study was performed to identify pathogenic mutations in five consanguineous Pakistani CMT families negative for PMP22 duplication. Genomic screening was performed by application of whole exome sequencing. Results We identified five pathogenic or likely pathogenic homozygous mutations in four genes: c.2599C > T (p.Gln867*) and c.3650G > A (p.Gly1217Asp) in
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28

"Preparation and Characterization of Calcium Cross-linked Carboxymethyl Tamarind Kernel Polysaccharide as Release Retardant Polymer in Matrix." Biointerface Research in Applied Chemistry 13, no. 2 (2022): 111. http://dx.doi.org/10.33263/briac132.111.

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This study aims to improve the efficacy of carboxymethyl tamarind kernel polysaccharide by cross-linking with Ca2+ ion and preparing its diclofenac sodium loaded matrix tablets for sustained drug delivery applications. Ionic gelation technique was used for cross-linking, and calcium chloride was used as a cross-linking agent. The native and cross-linked polysaccharide was characterized to analyze the change. The successful cross-linking of calcium was confirmed by infrared spectra by evaluating change in the functional group, while diffraction patterns revealed the change in crystallinity beha
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Malikongwa, Thatayaone, Saji Gomez, Meagle Joseph, Netravati, and Bintu Kuruvila. "Morphological and horticultural characteristics of some commercial banana (Musa spp.) cultivars of Kerala." Plant Science Today, March 6, 2022. http://dx.doi.org/10.14719/pst.1467.

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Morphological and horticultural characteristics of six cultivars of banana fruits (Musa spp.) that are commercially grown in Kerala, belonging to different genomic groups viz. Nendran (AAB), Pisang Lilin (AA), Karpooravalli (ABB), Njalipoovan (AB), Grand Naine (ABB) and Yangambi (KM-5) (AAA) were evaluated. The morphological traits were characterized using Banana Descriptors established by IPGRI (1996), from which 9 characters were selected for quantitative analysis. Horticultural characters on variables such as number of fruits per bunch, fruit length (cm), fruit pedicel length (mm), fruit pe
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H, Xu, Ying G, Qian H, et al. "Charcot-Marie-Tooth Disease 4G Caused by Homozygous Deletion of Exon 4 in HK1 Gene due to Inbreeding: A Case Report and Literature Review." Journal of Pediatrics & Child Health care 7, no. 1 (2022). http://dx.doi.org/10.26420/jpediatrchildhealthcare.2022.1054.

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Objectives: The objective is to investigate the clinical and genotypic characteristics of Charcot-Marie-Tooth disease, caused by HK1 gene mutation. Methods: The detailed medical history of the child was collected and the clinical symptoms were summarized. The genomic DNA was extracted from the 2ml of peripheral blood of child and their parents, and the whole exome sequencing was performed, and the related literatures were reviewed. Results: A 7-year-old girl with unstable walking for 7 months, left claudication, obvious valgus of left foot, unable to squate , unable to jump on one foot, grade
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Baudou, Eloïse, Claude Cances, Corinne Magdelaine, et al. "Unexpected Intermediate Nerve Conduction Velocity Findings in Charcot-Marie-Tooth Syndromes Classified as Demyelinated or Axonal in a Pediatric Population." Neuropediatrics, March 16, 2022. http://dx.doi.org/10.1055/s-0042-1743438.

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Abstract Introduction Among the hereditary motor and sensory neuropathies (HMSN), demyelinating forms are the best characterized, with a clear predominance of CMT1A. The axonal and intermediate forms are less described. The aim of this study is to report the genetic diagnosis of Charcot-Marie-Tooth (CMT) according to the nerve conduction velocity (NCV) findings in a pediatric population. Methods We retrospectively described a population of HMSN children with a confirmed genetic diagnosis of demyelinated, intermediate, or axonal forms. We compared the results of the genetic analyses with those
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