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1

Vieira, Karine Moura. "O desafio de narrar uma vida : a crítica genética no estudo da biografia como gênero jornalístico." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/30217.

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Esta dissertação analisa a biografia como gênero jornalístico através da aplicação dos procedimentos da Crítica Genética ao processo de produção da obra Padre Cícero – poder, fé e guerra no sertão, do jornalista Lira Neto. Procura-se identificar e compreender as características e especificidades que podem vir a definir a biografia como um gênero jornalístico - critérios de noticiabilidade, valores-notícia, tratamento e relação com as fontes e as estratégias comunicativas utilizadas para produzir a narrativa. Para tanto, realiza-se um estudo de gênese dos documentos, cadernetas e manuscritos qu
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2

Aston, Elizabeth Jane. "Critical mutation rates in small populations." Thesis, Keele University, 2014. http://eprints.keele.ac.uk/1321/.

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Mutation introduces change at the sequence level. There is a critical mutation rate above which changes occur too frequently for natural selection to maintain the population's genetic makeup. This thesis examines the relationship between this critical mutation rate and the number of individuals in the adapting population. It presents an algorithmic method capable of providing widely applicable results in haploid and diploid populations, and varies this method against analytical models for the error threshold. Use of the method led to the discovery of an exponential relationship between the cri
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3

Johansson, Christian, and Gustav Evertsson. "Optimizing Genetic Algorithms for Time Critical Problems." Thesis, Blekinge Tekniska Högskola, Institutionen för programvaruteknik och datavetenskap, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-4993.

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Genetic algorithms have a lot of properties that makes it a good choice when one needs to solve very complicated problems. The performance of genetic algorithms is affected by the parameters that are used. Optimization of the parameters for the genetic algorithm is one of the most popular research fields of genetic algorithms. One of the reasons for this is because of the complicated relation between the parameters and factors such as the complexity of the problem. This thesis describes what happens when time constraints are added to this problem. One of the most important parameters is popula
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4

Difford, Gareth Frank. "Critical assessment of the “internal reference” method to eliminate non-genetic effects within a Combined Family Selection program on the abalone species (Haliotis midae)." Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85658.

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Thesis (MScAgric)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The aim of this study was to critically assess the implementation of the internal reference method within the most recent 173 full-sibling growth trial of the Innovation Fund Abalone Breeding Project. The trial was conducted over two locations for a period of five years, with minimal replication for the majority of test families and a single full-sibling family was entered into each experimental unit (basket) as an internal reference group. The primary focus was firstly, to validate the performance of the internal refe
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5

French, Graham Christopher. "Conservation genetics of the critical plant genus Euphrasia L. in Britain." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/13856.

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Recent national and international conservation legislation has led to an increased focus on ‘prioritised species lists’ for the allocation of conservation resources. However, prioritised species lists become problematic when there are difficulties in species delimitation.  One particularly complex group accounting for the majority of these problems is <i>Euphrasia</i>. The goal of this thesis is to use molecular markers to evaluate taxon limits and evolutionary processes in British <i>Euphrasia</i> to clarify the most appropriate approach for conservation. The results show that the major repro
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6

Duty, Timothy Lee. "Broken symmetry and critical phenomena in population genetics : the stepping-stone model." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0018/NQ56536.pdf.

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7

Richardson, Rose. "The critical role of p63 during palatal shelf fusion." Thesis, University of Manchester, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634942.

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Cleft palate affects approximately 1 in 2000 live births resulting in considerable morbidity to affected individuals and their families. Evidence that the p63 gene is mutated in at least seven human developmental syndromes which are each characterised by varying extents of orofacial clefting, coupled to the severe facial dysmorphism displayed by the p63 mutant mouse, highlight the need to elucidate the role of the p63 during normal and aberrant palatogenesis. In mice, secondary palate development closely mirrors that occurring in humans; consequently, the mouse is a pre-eminent model organism
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8

Eggers, Ben. "Identifying phenotypic traits critical for breeding winter malting barley adapted to Ohio and the genomic regions affecting those traits." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1607035449218475.

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9

Appanah, Rowin. "Replisome-mediated homeostasis of DNA/RNA hybrids in eukaryotic genomes is critical for cell fates and chromatin stability." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/100501/.

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During DNA replication, forks often stall upon encountering obstacles blocking their progression. Cells will act to speedily remove or overcome such barriers, thus allowing complete synthesis of chromosomes. This is the case for R-loops, DNA/RNA hybrids that arise during transcription. One mechanism to remove such R-loops involve DNA/RNA helicases. Here, I have shown that one such helicase, Sen1, associates with replisome components during S phase in the model organism S. cerevisiae. I demonstrate that the N-terminal domain of Sen1 is both sufficient and necessary for the interaction of the pr
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10

Silva, Joyce do Rosario da. "Analise critica da expressão do gene da mucina 1(MUC1) no carcinoma papilifero da tireoide : correlações clinicas e anatomo-patologicas." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310273.

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Orientador: Laura Sterian Ward<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-13T00:19:00Z (GMT). No. of bitstreams: 1 Silva_JoycedoRosarioda_D.pdf: 4211439 bytes, checksum: d230e48c7d6fd16a7f9c75667ad83f9a (MD5) Previous issue date: 2009<br>Resumo: A maior expressão de MUC1 tem sido relacionada com o pior prognóstico de diversas malignidades como o câncer de mama e pâncreas. Aproximadamente 20% dos carcinomas diferenciados da tiróide (CDT) evoluem com recidivas locais e a distância. O nosso objetivo foi o de aval
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11

Catita, Flávia Barretto Correa. "Por uma edição crítico-genética virtual do livro Histórias da meia-noite, de Machado de Assis." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/8/8149/tde-28112014-113120/.

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Esta dissertação tem por objetivo elaborar uma Edição Crítico-Genética Virtual dos contos reunidos no livro Histórias da meia-noite, de Machado de Assis, os quais foram inicialmente publicados no periódico Jornal das Famílias. O trabalho pretende ressaltar as mudanças, supressões e acréscimos realizados pelo autor com a finalidade de esclarecer os processos de criação subjacentes à reescrita dos contos, assim como estabelecer relações entre os veículos de publicação e os diferentes perfis de leitores e compreender como o escritor se posicionava diante dessas peculiaridades. Pretende-se ainda d
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12

Bech, Linda. "Genetic and phenotypic characterization of trypanosomas." Thesis, Mälardalen University, School of Sustainable Development of Society and Technology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-6435.

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<p> </p><p><em>Trypanosoma theileri</em>, of the subgenus <em>Megatrypanum, </em>a non-pathogenic cosmopolitan blood dwelling parasite of bovine. <em>T. theileri </em>can be cultured at room temperature in several culture media.</p><p>Blood samples were collected from deer's. To see if the blood was infected with trypanosomes it was cultivated in 2 ml sheep blood or cell cultivation medium DMEM with antibiotics.</p><p>Growth was detected by microscopy to see if there were any trypanosomes.</p><p>To determine the species of trypanosomes that was in the deer blood a DNA-preparation was done befo
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13

Wang, Xun. "IRF3 is a Critical Regulator of Adipose Glucose and Energy Homeostasis." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10537.

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Obesity is associated with a state of chronic inflammation, which is believed to contribute to insulin resistance. We previously identified interferon regulatory factor 3 (IRF3) as an anti-adipogenic transcription factor with high expression in adipocytes. Because IRF3 is known to drive expression of pro-inflammatory genes in immune cells, we hypothesized that it may also promote inflammation and insulin resistance in adipocytes. Consistent with our expectations, we found that the expression of inflammatory genes in adipocytes was induced by IRF3 overexpression, while knockdown of IRF3 had the
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14

Lisboa, Ederval de Souza. "Análise e otimização da resposta em dinâmica de rotores." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/62045.

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Grandes esforços vêm sendo realizados atualmente com o objetivo de diagnosticar vibrações em estruturas e equipamentos, para máquinas rotativas se requer atenção ainda maior, pois correm o risco de se auto excitarem. Este trabalho tem por objetivo expor uma metodologia em dinâmica de rotores para diminuição da amplitude da resposta no domínio da frequência. Com essa finalidade, o rotor utiliza uma discretização de elementos finitos de viga de Timoshenko com funções da classe C0. A programação é implementada no programa acadêmico Meflab desenvolvida na plataforma do software MATLAB®, e no softw
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15

Corrêa, Elisete Márcia. "Expressão heteróloga, purificação e caracterização das proteínas humanas DCRA (Down Syndrome Critical Region Gene A) e DSCR8 (Down Syndrome Critical Region Gene 8)." Universidade Federal de São Carlos, 2004. https://repositorio.ufscar.br/handle/ufscar/5372.

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Made available in DSpace on 2016-06-02T20:20:28Z (GMT). No. of bitstreams: 1 TeseEMC.pdf: 2324718 bytes, checksum: 03bf0e57dab75b9f8e1c149ff3e678cd (MD5) Previous issue date: 2004-01-27<br>Down syndrome is the most frequent cause of mental retardation affecting millions of people worldwide and results from full or partial trisomy of chromosome 21 (HC21). Rare cases of partial trisomy allowed the identification of a small region in HC21 common to all carriers called Down Syndrome Critical Region. The genes DCRA and DSCR8, mapped to this region, encode two proteins of unknown function. With th
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16

Schweers, Nicholas Joseph. "Genetic Analysis of a Microvirus Major Spike Protein: A C-Terminal Region Critical for Assembly." Thesis, The University of Arizona, 2014. http://hdl.handle.net/10150/321950.

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17

Renwick, Juanita. "Population structure and genetic diversity of Southeast Queensland populations of the Wallum Froglet, Crinia Tinnula (Tschudi)." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16181/.

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Genetic diversity is a fundamental attribute that contributes to a species evolutionary survival. In recent times, conservation managers have recognized the need to preserve genetic diversity of declining species, and have also acknowledged the utility of genetic markers for describing genetic and ecological relationships within and among populations. Information obtained from genetic studies can be used in conjunction with information on population demography, land use patterns and habitat distribution to develop effective management strategies for the conservation of species in decline. T
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18

Wekwete, Chessman Tavarwisa. "Genetics and critical illness insurance underwriting : models for breast cancer and ovarian cancer and for coronary heart disease and stroke." Thesis, Heriot-Watt University, 2002. http://hdl.handle.net/10399/1157.

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19

Le, Coyte Hopkins Catherine Marie Ginette. "Challenge not crisis : an exploration of the role of genetic counselling for Turner syndrome, using an 'across the life span' approach, enabling families and individuals to meet the challenge." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/209527.

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An exploratory pilot study was conducted to identify specific experiences, perceptions and challenges of participants affected by Turner Syndrome in Hong Kong. It was important to discover how issues concerning fertility, menstruation, ovarian function and ovarian insufficiency and hormone replacement therapy, which are important to these women have impacted their psychosocial wellbeing, psychosocial experiences and their relationships. An ‘across the life span’ approach was used to explore significant issues at various stages or ‘moments’ of their lives, and which they perceive to be importan
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20

Aisenberg, Jeremy Charles. "A Critical Review of Telomerase Biology and Model Systems for the Study of Telomerase." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/2120.

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21

Kumbier, Alana. "Ephemeral Material: Developing a Critical Archival Practice." Columbus, Ohio : Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1236198205.

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22

Bilginer, Onur. "Control And Manipulation Of Life: A Critical Assessment Of Genetics Through The Perspectives Of Hans Jonas, Martin Heidegger And Michel Foucault." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607453/index.pdf.

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This study is on the political and ethical aspects of recent advances in genetics. Its aim is to explicate the scientific and technological premises of genetics along historical, philosophical and political axes by employing the critical perspectives of Jonas, Heidegger and Foucault. Starting the discussion from a brief account of scientific and technological revolutions initiated in the 16th and 17th centuries, I defend the thesis that the idea of control and manipulation of life is not a novelty introduced by genetics, but a historical orientation underlying modern man&rsquo<br>s metaphysica
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23

McCausland, Jamieson. "A Proactive Risk-Aware Robotic Sensor Network for Critical Infrastructure Protection." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/30328.

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In this thesis a Proactive Risk-Aware Robotic Sensor Network (RSN) is proposed for the application of Critical Infrastructure Protection (CIP). Each robotic member of the RSN is granted a perception of risk by means of a Risk Management Framework (RMF). A fuzzy-risk model is used to extract distress-based risk features and potential intrusion-based risk features for CIP. Detected high-risk events invoke a fuzzy-auction Multi-Robot Task Allocation (MRTA) algorithm to create a response group for each detected risk. Through Evolutionary Multi-Objective (EMO) optimization, a Pareto set of optimal
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24

Cardoso, Jorge Fernando dos Anjos. "Muda critica no camarão rosa pernaeus paulensis perez farfante, 1967 (crustacea, deca poda, penaeidae) cultivado em viveiros no Estado de Santa Catarina." reponame:Repositório Institucional da UFSC, 1997. http://repositorio.ufsc.br/xmlui/handle/123456789/77039.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Agrarias<br>Made available in DSpace on 2012-10-17T00:14:56Z (GMT). No. of bitstreams: 0<br>Os estádios de desenvolvimento do télico e do petasma de Penaeus (Farfantepenaeus) paulensis Pérez Farfante, 1967 foram utilizados para confirmar a ocorrência de mudas críticas associadas às descontinuidades já descritas em distribuições de crescimerto relativo entre comprimento da carapaça e dimensões de segmentos abdominais. As dimensões utilizadas foram o comprimento da carapaça (CC), comprimento do abdome (CA), compr
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25

Lytrivi, Maria. "Genetic and lipotoxic endoplasmic reticulum stress in pancreatic β cells: a critical process in common and rare forms of diabetes". Doctoral thesis, Universite Libre de Bruxelles, 2020. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305600.

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ABSTRACTThe prevalence of diabetes is increasing dramatically, incurring a major health and socioeconomic burden. Type 2 diabetes (T2D), the most prevalent form of diabetes, results from a variable combination of insulin resistance and insulin deficiency, secondary to pancreatic β-cell failure. These defects are caused by a complex interplay between genetic and environmental/ lifestyle factors. Among the latter, poor dietary quality is a crucial driver of T2D development. Although adopting healthy dietary habits is considered as a mainstay for T2D prevention, what constitutes a healthy diet re
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26

Munoz, Marcia Medicine UNSW. "The EDD protein is a critical mediator in the DNA damage response." Awarded by:University of New South Wales. Medicine, 2006. http://handle.unsw.edu.au/1959.4/25977.

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An intact cellular response to DNA damage is important for the maintenance of genomic stability and tumour prevention. EDD, the human orthologue of Drosophila melanogaster ???hyperplastic discs???, is over-expressed or mutated in a number of common human cancers. EDD is a progestin regulated gene that encodes an E3 ubiquitin ligase involved in cell communication and cell adhesion, and although it has also been implicated in the DNA damage response through its association with DNA damage proteins, a definitive role has yet to be demonstrated. The work presented herein shows that EDD is necessar
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27

Conroy, Amy. "E-racing the Genetic Family Tree: A Critical Race Analysis of the Impact of Familial DNA Searching on Canada's Aboriginal Peoples." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34285.

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Canada established its National DNA Data Bank (NDDB) in 2000. Since that time, the NDDB has assisted in the solving of numerous criminal investigations. The NDDB has two indexes: the convicted offender index, which holds the identifiable DNA of persons convicted of designated crimes, and the anonymous crime scene index, which holds anonymous DNA collected from crime scenes. A match to a crime scene profile provides criminal investigators with extremely valuable evidence linking a suspect to a crime scene and the NDDB has been used to identify perpetrators in thousands of crimes in Canada. B
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28

Greig, Kylie Tara. "Critical roles for the transcription factor c-Myb in early B cell development /." Connect to thesis, 2009. http://repository.unimelb.edu.au/10187/3824.

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Thesis (Ph.D.)--University of Melbourne, The Walter and Eliza Hall Institute of Medical Research, The Division of Immunology and the Division of Molecular Medicine, Dept. of Medical Biology, Faculty of Medicine and Dentistry, 2009.<br>Typescript. Includes bibliographical references (p. 133-165)
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Luderer, Cynthia Arantes Ferreira. "O processo de comunicação na criação do carnavalesco Raul Diniz." Pontifícia Universidade Católica de São Paulo, 2007. https://tede2.pucsp.br/handle/handle/4960.

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Made available in DSpace on 2016-04-26T18:16:31Z (GMT). No. of bitstreams: 1 Cynthia Arantes Ferreira Luderer.pdf: 12197386 bytes, checksum: 03c2732148ebc829d9075bb8e4ef3104 (MD5) Previous issue date: 2007-10-26<br>Secretaria da Educação do Estado de São Paulo<br>This text has the objective to analyze the communication process of carnavalesco Raul Diniz creation and point how much the limits and restrictions that come from mass media and communications network of Samba s school from São Paulo, interfere on this professional s procedures and choices for the Samba s school parade show creation
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Armbruster, Diana. "The impact of serotonergic and dopaminergic genetic variation on endophenotypes of emotional processing." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-63574.

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Decades of research in quantitative genetics have found substantial heritability for personality traits as well as for mental disorders which formed the basis of the ongoing molecular genetic studies that aim to identify genetic variations that actually contribute to the manifestation of complex traits. With regard to psychological traits, genetic variation impacting neurotransmitter function have been of particular interest. Additionally, the role of environmental factors including gene × environment interactions has been further investigated and the impor-tance of developmental aspects has b
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Tavares, Daniel Jorge. "Sequences Required for Neurotensin Receptor-1 Gene Expression in N1E-115 Neurosblastoma Cells: Critical Importance of a CACCC Element for Activation During DMSO-Induced Neuronal Differentiation: a Dissertation." eScholarship@UMMS, 2000. https://escholarship.umassmed.edu/gsbs_diss/40.

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The promoter sequence of the mouse high affinity neurotensin receptor, Ntr-1, gene was cloned and characterized, sequences required for positive regulation in N1E-115 cells were localized, and at least two different peptides from these cells were shown to make specific contacts within the most potent positive regulatory element. A mouse neuroblastoma cell line, N1E-115, treated with 1.5% DMSO for 72 hours induces gene expression of both endogenous Ntr-l, and reporter constructs driven by the NTR-1 promoter, by 3 - 4 fold. The sequence ofthe NTR-1 promoter has no canonical TATA box, but is GC r
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Chen, Yaoyu. "Critical Molecular Pathways in Cancer Stem Cells of Chronic Myeloid Leukemia: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/536.

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Chronic myeloid leukemia (CML) is a disease characterized by the expansion of granulocytic cells. The BCR-ABL tyrosine kinase inhibitor imatinib, the frontline treatment for Ph+ leukemias, can induce complete hematologic and cytogenetic response in most chronic phase CML patients. Despite the remarkable initial clinic effects, it is now recognized that imatinib will unlikely cure patients because a small cell population containing leukemic stem cells (LSCs) with self-renewal capacity is insensitive to tyrosine kinase inhibitors. In Chapter I, I briefly review the BCR-ABL kinase and its related
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Hannum, Juliana Santos de Souza. "ACONSELHAMENTO GENÉTICO: ANÁLISE E CONTRIBUIÇÕES A PARTIR DO MODELO DO ACONSELHAMENTO PSICOLÓGICO." Pontifícia Universidade Católica de Goiás, 2011. http://localhost:8080/tede/handle/tede/1784.

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Made available in DSpace on 2016-07-27T14:19:50Z (GMT). No. of bitstreams: 1 JULIANA SANTOS DE SOUZA HANNUM.pdf: 943345 bytes, checksum: e01f20b8b7c8cdbfd7ec222ca3c63ba9 (MD5) Previous issue date: 2011-01-10<br>The GC is defined as a clinical process dedicated to the understanding of the diagnosis of a genetic condition. The main objective of the GC is to guide individual comprehension of condition and its prognosis, though the risk of occurrence or recurrence of the disorder in the family to a final decision making regarding the genetic phenomenon. The current study aimed to analyze the mod
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Rutledge, Charles Jerry 1941. "Physiological Ecology, Population Genetic Responses and Assemblage Stability of Fishes in Two Southwestern Intermittent Stream Systems." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc277808/.

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Six sites within the Denton and Hickory Creek watersheds were sampled over three years to assess the impact of seasonal intermittent stream conditions on the ichthyofauna. An integrated approach using field and laboratory techniques was employed to evaluate the responses of the fishes.
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Pereira, Denise Rocha Pereira [UNESP]. "Consumismo e educação infantil: um estudo sobre crenças e hábitos de docentes e alunos." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/154332.

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Submitted by DENISE ROCHA PEREIRA (deniserochap@hotmail.com) on 2018-06-22T06:28:05Z No. of bitstreams: 1 Pereira, D. R. tese 330p completa e finalizada 18 de junho.pdf: 4163242 bytes, checksum: ebe0602ae3350c66c89d58adad130e81 (MD5)<br>Approved for entry into archive by Satie Tagara (satie@marilia.unesp.br) on 2018-06-22T18:18:57Z (GMT) No. of bitstreams: 1 pereira_dr_dr_mar.pdf: 4163242 bytes, checksum: ebe0602ae3350c66c89d58adad130e81 (MD5)<br>Made available in DSpace on 2018-06-22T18:18:57Z (GMT). No. of bitstreams: 1 pereira_dr_dr_mar.pdf: 4163242 bytes, checksum: ebe0602ae3350c66c89
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Sheumack, Michele Denise, and n/a. "StarLink(TM) Corn: A Case Study." Griffith University. School of Science, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040401.151800.

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The 18 September 2000 disclosure that StarLink corn, a genetically engineered variety not approved for human consumption, had been detected in food was a seminal event in agricultural biotechnology. This thesis presents a comprehensive case study of the StarLink incident (part one), reviews the StarLink situation in terms of crisis management theory (part two) and develops crisis management theory using the StarLink incident as an example of a crisis (part three). Part one provides background information, then a meticulous day-by-day account of StarLink-related events. Part two presents a det
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Silva, Ana Maria Formoso Cardoso e. "O percurso de um projeto de Oswald de Andrade = memória da criação de Marco Zero." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270196.

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Orientador: Vera Maria Chalmers<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem<br>Made available in DSpace on 2018-08-16T22:48:39Z (GMT). No. of bitstreams: 1 Silva_AnaMariaFormosoCardosoe_D.pdf: 17284982 bytes, checksum: 7642e9a50dfe0c96ebd45a9e1a0b38e8 (MD5) Previous issue date: 2010<br>Resumo: Nos últimos vinte anos de sua vida, Oswald de Andrade esteve envolvido na escrita de Marco Zero, um ciclo de romances em que ele pretendia retratar a sociedade paulista após a crise de 1929. Apesar da grande divulgação do projeto na época, o trabalho desen
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Orsini, Sarah. "Les "Carmina" de Pascoli : édition traduite et commentée d'une sélection de poèmes latins et édition numérique d'une sélection de brouillons." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE2090.

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Giovanni Pascoli (1855-1912) est un classique de la littérature italienne. Poète bilingue écrivant en italien et en latin, il s’est illustré dans le domaine de la littérature néo-latine en composant des poèmes qui ont remporté le certamen poeticum hoeufftianum. Son œuvre latine, les Carmina, est méconnue en France. Le premier objectif de cette recherche doctorale est de proposer une édition bilingue traduite et commentée d’une sélection des poèmes latins de Pascoli, accessible à un public français non spécialiste de littérature latine ou italienne. Nous avons tenté de sélectionner des poèmes d
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Santos, Paula Constante Silva. "Arquitetura e cinema em processo. Um estudo comparativo entre o criar e produzir arquitetônico e cinematográfico." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/16/16134/tde-03082012-140104/.

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Esta dissertação trata das possíveis aproximações entre os campos da arquitetura e do cinema a partir de seus processos de criação e produção. Sob a luz dos estudos genéticos sobre o processo de criação artística foram realizadas entrevistas com arquitetos e cineastas com o objetivo de observar como acontece o criar e o produzir de seus objetos, isto é, o arquiteto quando projeta e constrói, o cineasta quando roteiriza e produz um filme. A partir destes relatos e dos registros de outros autores em relação aos seus processos, colhidos em fontes diversas, foram levantas semelhanças e contraponto
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Chaplin, Letícia da Costa. "De ausências & distâncias te construo : a poesia de Caio Fernando Abreu." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/27153.

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O presente trabalho caracteriza-se por apresentar, pela primeira vez, uma vertente pouco conhecida do escritor gaúcho Caio Fernando Abreu: a poesia. Essa pesquisa participa das discussões levantadas pela Crítica Genética, centrando-se na organização dos manuscritos dos 116 poemas, praticamente todos inéditos, visando a uma publicação, e no acompanhamento do percurso criativo do poeta. Para tanto, essa tese se estrutura em três etapas: fixação dos poemas; estudo das campanhas de escritura através de poemas representativos; análise dos temas da falta, do olhar e da memória, fundamentada nas refl
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Jouffroy, Olivier. ""El Maquiavelismo degollado" (1636-37) de Claude Clément, édition et étude : l'évolution d'une pensée politique entre mondes ancien et moderne." Thesis, Bourgogne Franche-Comté, 2017. http://www.theses.fr/2017UBFCC023/document.

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El maquiavelismo degollado est un défi lancé à tous les hommes de pouvoir tentés de suivre la voie pragmatique de Machiavel plutôt que celle tracée par l’Église catholique romaine ; son auteur, Claude Clément, fut alors considéré comme le plus radical des penseurs de l’anti-machiavélisme. Son œuvre n’a pourtant jamais été rééditée et reste mal connue probablement parce qu’elle est composée de trois textes publiés dans deux langues différentes et que sa version espagnole semble bien être une réécriture plutôt qu’une simple traduction. Parsemée de reproductions de documents, enrichie de nombreus
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Dos, Santos Thierry Proença. "De Ilhéus a Canga, de Horácio Bento de Gouveia : a narrativa e as suas (re)escritas (com uma proposta de edição crítico-genética e com uma tradução parcial do romance para francês)." Paris 3, 2007. http://www.theses.fr/2007PA030121.

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Bien que l’écrivain Horácio Bento de Gouveia n’ait jamais théorisé ce concept, ce qui impressionne le plus dans son oeuvre est, en effet, la tentative de décrire et de définir l’ « insularité de Madère », par le biais d’une pratique discursive et d’un choix de thèmes qui indiquent cette notion. Outre que le premier roman de l’auteur soit, probablement, le plus illustratif de ce que nous venons d’énoncer, notre choix se doit au fait qu’il constitue un sujet fécond – grâce au matériel existant autour de lui et le potentiel littéraire et linguistique qu’il insère -, avec une incidence spéciale, e
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Pannard, Myriam. "Exploration de l’expérience vécue et de la mise en sens des enjeux éthiques et psychosociaux lies aux innovations technologiques et thérapeutiques en oncogénétique : une approche critique." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE2118/document.

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L'oncogénétique, l'étude des prédispositions héréditaires au cancer, constitue une discipline médicale dynamique, faisant l'objet de nombreuses innovations, tant technologiques que thérapeutiques. Les progrès scientifiques en oncogénétique rendent le recours aux tests génétiques à la fois moins coûteux, plus rapide et plus efficace, ce qui soulève ou réactualise paradoxalement de nombreux enjeux éthiques et psychosociaux tels que la capacité des patients à formuler un consentement éclairé ou le risque de dérives liées à des mésusages des tests génétiques. Face à ces changements, nous avons cho
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Martin, Romain. "Conception d’une architecture robuste pour l’acquisition de grandeurs physiques dans un système aéronautique critique : application à la mesure de température, pression, couple, et vitesse d’une turbomachine." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0060/document.

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L’acquisition de paramètres physiques tels que la température, la pression, le couple et la vitesse est nécessaire aux systèmes aéronautiques critiques afin d’atteindre et d’assurer les performances requises de disponibilité et de sécurité de fonctionnement. L’acquisition de ces paramètres physiques nécessite donc la mise en oeuvre de technologies et de techniques hautement éprouvées pouvant supporter les conditions de fonctionnement sévères.L'objectif des travaux présentés dans ce mémoire est de proposer une nouvelle architecture de chaîne d'acquisition de grandeurs physiques pour être intégr
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Raudenská, Lenka. "Metriky a kriteria pro diagnostiku sociotechnických systémů." Doctoral thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-233879.

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This doctoral thesis is focused on metrics and the criteria for socio-technical system diagnostics, which is a high profile topic for companies wanting to ensure the best in product quality. More and more customers are requiring suppliers to prove reliability in the production and supply quality of products according to given specifications. Consequently the ability to produce quality goods corresponding to customer requirements has become a fundamental condition in order to remain competitive. The thesis firstly lays out the basic strategies and rules which are prerequisite for a successful w
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Cheng, Shufu, and 鄭書甫. "Application of Genetic Algorithms and NeuralNetwork on Financial Crisis Prediction." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/47730540264073187698.

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碩士<br>長榮大學<br>經營管理研究所<br>99<br>As the frequency of enterprise financial crisis gets higher, early warnings of financial crisis are paid more and more attention. There have been studies on financial crisis early-warning models for several years. This study first collated and analyzed many commonly-used financial early-warning models. Secondly, predictions of financial crisis were carried out by means of three kinds of models, i.e. Logit model, artificial neural network model and genetic algorithm model, and then the results of the predictions were compared. The results showed that the accuracy
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Singer, Ruth Arielah. "Long noncoding RNAs are critical regulators of pancreatic islet development and function." Thesis, 2019. https://doi.org/10.7916/d8-nnax-mb40.

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Diabetes is a complex group of metabolic disorders with genetic, immunological, and environmental etiologies. Decades of diabetes research have elucidated many genetic drivers of normal islet function and dysfunction. Furthermore, genome wide associated studies (GWAS) have discovered that most diabetes susceptibility loci fall outside of coding regions, which suggests a role for noncoding elements in the development of disease. This highlights our incomplete understanding of the islet regulome and suggests the need for detailed functional analyses of noncoding genes to precisely determine thei
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Killela, Patrick J. "Genetic Studies Identify Critical Biomarkers and Refine the Classification of Malignant Gliomas." Diss., 2014. http://hdl.handle.net/10161/9080.

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<p>Gliomagenesis is driven by a complex network of genetic alterations and while the glioma genome has been a focus of investigation for many years; critical gaps in our knowledge of this disease remain. The identification of novel molecular biomarkers remains a focus of the greater cancer community as a method to improve the consistency and accuracy of pathological diagnosis. In addition, novel molecular biomarkers are drastically needed for the identification of targets that may ultimately result in novel therapeutics aimed at improving glioma treatment. Through the identification of new bio
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謝可欣. "A study on the 7th graders' critical reading comprehension about genetic news." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/97589777038433602492.

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LaCombe, Jonathan M. "DYRK1A-Related Trabecular Defects in Male Ts65Dn Mice Emerge During a Critical Developmental Window." Thesis, 2021. http://dx.doi.org/10.7912/C2/39.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Down syndrome (DS) is a complex genetic disorder caused by the triplication of human chromosome 21 (Hsa21). The presence of an extra copy of an entire chromosome greatly disrupts the copy number and expression of over 350 protein coding genes. This gene dosage imbalance has far-reaching effects on normal development and aging, leading to cognitive and skeletal defects that emerge earlier in life than the general population. The present study begins by characterizing skeletal development in young male Ts65Dn mice to test the hypothes
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