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Tesi sul tema "Cyclodextrins"

Autore: Grafiati
Pubblicato: 4 giugno 2021
Ultima modifica: 25 luglio 2025

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1

Nemeth, Richard Desider. "Linked Beta-Cyclodextrins." W&M ScholarWorks, 1988. https://scholarworks.wm.edu/etd/1539625449.

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2

Liu, Enxu. "Design of molecular Brownian ratchets exploiting the asymmetry of functionalized cyclodextrins." Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS654.pdf.

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Abstract (sommario):
Au cours des dernières années, les avancées dans le domaine des machines moléculaires ont été remarquables. Néanmoins, la réalisation d'un mouvement unidirectionnel contrôlé au sein de ces nanostructures reste compliquée. L'objet de cette thèse est d'exploiter l'asymétrie intrinsèque de la cyclodextrine (CD) pour développer des machines moléculaires capables de réaliser un mouvement unidirectionnel. Une série de [2]rotaxanes, comportant une α-CD perméthylée simple ou fonctionnalisée avec une amine sur le col primaire a été synthétisée.Dans une première partie, un mécanisme de cliquet d'informa
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3

Brown, Susan Elizabeth. "Molecular recognition by cyclodextrins /." Title page, contents and abstract only, 1994. http://web4.library.adelaide.edu.au/theses/09PH/09phb8798.pdf.

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4

Yan, Jinglan. "Sulfated ß-cyclodextrins in enantiomeric separations and mobility conservation model in cyclodextrin-mediated capillary electrophoresis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ35009.pdf.

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5

Haskard, Carolyn Anne. "Multiple recognition by modified cyclodextrins." Title page, contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phh349.pdf.

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Copy of author's previously published article inserted. Includes bibliographies This thesis studies the B-cyclodextrins which are modified at the primary rim to incorporate an additional coordination or hydrophobic recognition site. The natural organic host, cyclodextrin and its chemically modified derivatives, are utilised as hosts for the inclusion of a range of guests. The study contributes to understanding the fundamental factors influencing selectivity of binding and the stability of the complexes formed when a guest is bound essentially at two recognition sites.
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6

Kean, Suzanna Dawn. "Modified cyclodextrins and their complexes." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phk243.pdf.

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Abstract (sommario):
Addendum page pasted onto front end paper. Copies of author's previously published articles inserted. Includes bibliographical references. Investigates the factors that govern the stability of cyclodextrin inclusion complexes with a range of systematically modified cyclodextrins.
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7

Palmer, Simon Richard Faunch. "Electroanalytical sensors using lipophilic cyclodextrins." Thesis, Durham University, 1997. http://etheses.dur.ac.uk/4753/.

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Lipophilic dialkylated-a-, β- and γ-cyclodextrin derivatives were used as selective ionophores for a series of clinically relevant ammonium ions, and as enantioselective ionophores for both a- and β-aryl ammonium ions. Sensitive and selective potentiometric detection of the local anaesthetics lidocaine and bupivacaine was achieved by using 2,3,6 trioctyl-β-cyclodextrin as the ionophore, leading to micromolar detection limits. Interference studies showed that the simulated clinical electrolyte background caused minimal interference whereas organic interferents of similar size and charge caused
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8

Jones, S. P. "Interaction of drugs with cyclodextrins." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355923.

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9

De, Vries Elise Janine Christl. "Inclusion of alkylparabens in cyclodextrins." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/6302.

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Includes bibliographical references.<br>The aim of this thesis was to prepare crystalline inclusion complexes with cyclodextrins (CDs), as hosts, and drugs, as guests, characterise them using various methods and attempt to elucidate their structures by X-ray diffraction methods to establish the detailed mode of drug inclusion in the solid state. Cyclodextrins and their derivatives have a low polarity central void formed by linked glucose residues of varying numbers. This annular cavity is able to encapsualte low molecular weight molecules and is therefore responsible for the great interest in
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10

Al-Derbali, Meftah Abdulhafied. "Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability." University of the Western Cape, 2016. http://hdl.handle.net/11394/5052.

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Magister Pharmaceuticae - MPharm<br>Background: Zidovudine (AZT) is a very useful drug for the management of Human Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. Cyclodextrins (CD) are a class of compounds which can be used to form inclusion complexes with drugs such as AZT to improve it is taste, solubility and palatability. Purpose: This study complexed hydroxypropyl-beta-cyclodextrin (HPβCD) with AZT. The formulated inclusion complex was evaluated for suitability as a dosage form and as a tool for i
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11

Lock, Julia. "Cyclodextrins : molecular wheels for supramolecular chemistry /." Title page, table of contents and abstract only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phl8131.pdf.

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Thesis (Ph.D.)--University of Adelaide, School of Chemistry and Physics, Discipline of Chemistry, 2005?<br>"July 2004" Includes copies of publications by the author as appendix. Includes bibliographical references.
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12

Lee, Yann-Huei Phillip Ramapuram Jayachandra B. "Inclusion complexation of Gefitinib with cyclodextrins." Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/SUMMER/Pharmacal_Sciences/Thesis/Lee_Yann-huei_47.pdf.

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13

Cossette, Michael Vernie. "The Synthesis of Quinone-Capped Cyclodextrins." W&M ScholarWorks, 1988. https://scholarworks.wm.edu/etd/1539625451.

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14

Meijide, Suárez Jorge. "Confinement of metal complexes in NHC-cyclodextrins : structure, electrochemistry and catalysis." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS539.

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L'utilisation de métaux confinés dans des cavité est un outil intéressant dans le domaine de la catalyse en milieu confiné. Grâce à la forme conique des cyclodextrines (CD), la synthèse des NHC-pontées dérivés (ICyD) a été étudié. L’étude commence par la synthèse et la caractérisation de dérivés de Au(I) dans la cavité de la y-ICyD. Au cours de la synthèse, la formation d'un complexe AuCl3 plan carré (y-ICyD) a été observée. Celui-ci a conduit à la synthèse de complexes Au(III), Pd(II) et Pt(0) complexés par les ⍺-, β- et γ-CDs. Les structures 3D des complexes ont pu être modélisées grâce à l’
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15

Field, Michael J. "6A-w-Aminoalkylamino-Cyclodextrins : their preparation and studies of their self-inclusion complexes and catalytic nature /." Title page, contents and abstract only, 2000. http://web4.library.adelaide.edu.au/theses/09PH/09phf455.pdf.

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Thesis (Ph.D.)--University of Adelaide, Dept. of Chemistry, 2000?<br>Copy of author's previously published article, inserted. Errata sheet pasted opposite title page. Includes bibliographical references.
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16

Jarand, Curtis William. "Complexation of Organic Guests and Coordination of Metal Ions by Cyclodextrins: Role of Cyclodextrins in Metal-Guest Interactions." ScholarWorks@UNO, 2011. http://scholarworks.uno.edu/td/1319.

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Nitroaromatic explosives, such as trinitrotoluene (TNT), are of particular environmental concern due to their recalcitrance in soils and their potent toxicity and mutagenicity to both aquatic and mammalian species. TNT was the most widely used military explosive through the era encompassing both the First and Second World Wars. As a result, there is widespread contamination of soils by TNT around weapons manufacture, testing, and disposal facilities. Fenton chemistry (ferrous ion catalyzed generation of hydroxyl radicals) has shown utility in the remediation of TNT in soils but it suffers from
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17

Colesnic, Dmitri. "Architectures supramoléculaires hiérarchiques à base de cyclodextrines." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066616/document.

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La Nature crée des assemblages, de structure primaire (1D) et secondaire (3D) bien maîtrisées, qui réalisent des fonctions biologiques complexes. Dans ce contexte, notre but est de construire des assemblages supramoléculaires hiérarchiques utilisant des monomères de cyclodextrines (CDs), préparés selon la méthode de polyfonctionnalisation des CDs, développée au laboratoire. L'existance d'équilibres compétitifs (auto-inclusion et dimérisation tête à tête) empêchant l'accès aux polymères supramoléculaires (PS) de plus grande taille, a été démontrée. Ainsi, pour s'affranchir de ces espèces compét
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18

Serno, Tim. "Inhibition of therapeutic protein aggregation by cyclodextrins." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-131251.

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19

Martinic, Goran (Gary), of Western Sydney Hawkesbury University, of Science Technology and Environment College, and School of Environment and Agriculture. "Cyclodextrins as potential human anti-atherosclerotic agents." THESIS_CSTE_EAG_Martinic_G.xml, 2001. http://handle.uws.edu.au:8081/1959.7/129.

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Abstract (sommario):
Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides. Since it is believed that OxC blocks the removal of normal cholesterol from cells in the artery wall, it is possible that selective removal of OxC in the vessel wall in-vivo may prevent or reverse atherosclerosis.As a prelude to major studies, this research project was designed to answer two critical questions; 1/. What is the best route for delivery of CD. 2/. How do animals (apoE-/- mice) tolerate it. Pilot studies were established and results noted. These studies have provided valuable information in the apoE-/- mouse for
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20

Bauer, Martin. "Membrane functionalisation using polyrotaxanes with amphiphilic cyclodextrins." Strasbourg, 2011. http://www.theses.fr/2011STRA6190.

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Ce travail est destiné à la conception et à la caractérisation d’une nouvelle famille de ligands attachés, appelé “Sliding Tethered Ligands” (STLs). Ils sont à base de complexes topologiques entre des polymères et des cyclodextrines amphiphiles (CD), qui peuvent être insérées dans les membranes phospholipidiques. Au début, nous étudions les propriétés d’insertion membranaire des dérivés de CD amphiphiles modifiées avec du cholestérol, qui sont des ancres membranaires appropriées pour les STLs. Avec l’aide de la réflectivité de neutrons on peut démontrer que les résidus de CD montrent une remar
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21

Martinic, Gary. "Cyclodextrins as potential human anti-atherosclerotic agents." Thesis, View thesis View thesis, 2001. http://handle.uws.edu.au:8081/1959.7/129.

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Abstract (sommario):
Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides. Since it is believed that OxC blocks the removal of normal cholesterol from cells in the artery wall, it is possible that selective removal of OxC in the vessel wall in-vivo may prevent or reverse atherosclerosis.As a prelude to major studies, this research project was designed to answer two critical questions; 1/. What is the best route for delivery of CD. 2/. How do animals (apoE-/- mice) tolerate it. Pilot studies were established and results noted. These studies have provided valuable information in the apoE-/- mouse for
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22

Martinic, Gary. "Cyclodextrins as potential human anti-atherosclerotic agents /." View thesis View thesis, 2001. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030505.174617/index.html.

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Thesis (M.Sc.) (Honours) -- University of Western Sydney, Hawkesbury, 2001.<br>A thesis submitted in fulfilment of the rquirements for the award of the degree of MSc(Hons), University of Western Sydney, Hawkesbury Campus, 2001. Bibliography : leaves 263-294.
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23

Khrueawatthanawet, Thanaphon. "Synthesis of cyclodextrin-hexaphyrin hybrids en route to unorthodox π-type (anti)aromatic interaction receptors". Electronic Thesis or Diss., Sorbonne université, 2024. http://www.theses.fr/2024SORUS522.

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Contrairement à l'aromaticité de Hückel classique, peu de choses sont connues sur les aromaticités dites « non orthodoxes » (c'est-à-dire l'antiaromaticité de Hückel et l'aromaticité de Möbius) en raison de leur totale absence dans la nature et de la difficulté à les synthétiser. Par conséquent, peu d'études ont été menées pour explorer les interactions de type π impliquant ces aromaticities non orthodoxes. Cependant, ces caractéristiques se retrouvent dans la famille des dérivés porphyrinoïdes, en particulier les hexaphyrines, qui peuvent alternativement adopter un caractère Hückel antiaromat
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24

Worthington, Matthew Stanley. "Nifedipine-cyclodextrin binary systems : solid-state photostability and dissolution behaviour." Thesis, Rhodes University, 1998. http://hdl.handle.net/10962/d1007233.

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Nifedipine is a photolabile calcium channel antagonist which undergoes rapid photodegradation in solution and in solid-state with an accompanying loss of pharmacological potency and clinical efficacy. Nifedipine photostabilization which has received considerable attention has principally been achieved by physical obscuration and through the use of colourants or ultraviolet light absorbers incorporated into liquid preparations, translucent packaging materials, gelatin capsules and/or their fillings and tablet coatings or cores. This study was initiated by a South African pharmaceutical manufact
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25

Åström, Nina. "NADH/NAD⁺ analogues and cyclodextrins in enzyme mimicking systems an experimental and computational investigation /." Lund : Organic Chemistry 1, Lund University, 1995. http://catalog.hathitrust.org/api/volumes/oclc/39781586.html.

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26

Zhang, Pinglu. "Cyclodextrin-(N-Heterocyclic Carbene)-Metal Complexes for Cavity-Dependent Catalysis." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066380/document.

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Abstract (sommario):
Des complexes de Cyclodextrine (CD)-NHC-Métaux (NHC= Carbènes N-Hétérocycliques), comprenant des métaux tel que AgI, CuI et AuI ont été synthétisés. Une étude structurale a mis en évidence la position intra-cavitaire du métal, induisant des interactions C-H…M, C-H…X et π…X. L’influence du type de cavité (α-, β-, γ-CD) et du type de dérivés NHC (Imidazole, benzimidazole, triazole) a été étudiée. Les interactions diminuent avec l’augmentation de la taille de la cavité et en parallèle, celles-ci ont été amplifiées avec des dérivés NHC possédant un effet donneur plus fort. Les complexes de cuivre
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27

Murphy, Robert Scott. "Photophysical studies on the dynamics of guest complexation with cyclodextrins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0017/NQ47292.pdf.

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28

Anil, Gunaratne D. M. "Physical and chemical modification of some cereal, tuber and root starches and the roles of [beta]-cyclodextrin as a starch modifying agent." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37752753.

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29

Taweepreda, Wirach. "Studies of inclusion complexes of polymer and cyclodextrins." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420918.

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30

Ivanov, Anton Andreevich. "Supramolecular association of metal clusters with cyclodextrins : from interactions in solution to the design of mixed systems clusters-polyoxometalates." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLV095/document.

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Abstract (sommario):
Les travaux de cette thèse intitulée « Associations supramoléculaires des Complexes de clusters métalliques avec les cyclodextrines : Des interactions en solution à la conception de systèmes mixtes Clusters-polyoxométallates » portent sur l’encapsulation de clusters octaédriques par des oligosaccharides cycliques appelés cyclodextrines. La première partie de ce travail concerne l’étude en solution aqueuse du comportement de clusters de rhénium cationiques [Re6Q8(H2O)6]2+ (avec Q = S ou Se) ou anioniques du type [Re6Q8(CN)6]4- (avec Q = S, Se ou Te) vis-à-vis de cyclodextrines de type α, β et γ
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31

Azzi, Joyce. "Amélioration des qualités nutritionnelles et organoleptiques des aliments par encapsulation de composés actifs (arômes, vitamines, antioxydants, acides gras insaturés...)." Thesis, Littoral, 2017. http://www.theses.fr/2017DUNK0460/document.

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L'incorporation d'ingrédients bioactifs dans les produits alimentaires est en plein essor. Il a été démontré que ces ingrédients possèdents des propriétés biologiques importantes permettant l'amélioration de la santé et la prévention des maladies dites de civilisations. Toutefois, l'ajout de ces molécules bioactives est dans la plupart des cas impossible ou insuffisant, du fait que ces composés ne sont que peu solubles dans les systèmes aqueux et présentent i) une stabilité limitée contre les dégradations chimique ou physique, ii) une libération non contrôlée ou une faible biodisponibilité. Fa
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32

Pembouong, Gaëlle. "Caractérisation de polymères supramoléculaires hiérarchiques à base de cyclodextrines fonctionnalisées." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS005/document.

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Les systèmes moléculaires de taille nanométrique sont impliqués dans une grande variété de procédés et de fonctions biologiques. La compréhension des mécanismes permettant le contrôle de leur structure à plusieurs échelles présente un grand intérêt. Par exemple, malgré le défi que cela représente, il n'existe actuellement aucun système synthétique permettant la formation d'objets fibrillaires de diamètre monodisperse et modulable en milieu aqueux. L'objectif de ce travail est de développer une boite à outils moléculaires de cyclodextrines (CDs) sélectivement di-fonctionnalisées de façon à pouv
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33

Churamani-Poulenc, Rebecca. "Assemblages supramoléculaires de cyclodextrines fonctionnalisées comme outil de transfection." Electronic Thesis or Diss., Sorbonne université, 2024. http://www.theses.fr/2024SORUS078.

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La thérapie génique est un domaine scientifique crucial qui doit être davantage développé, et la crise du Covid-19 n'a fait que confirmer cette nécessité. Les virus sont connus pour être des vecteurs de matériel génétique très efficaces. Parmi eux, le virus de la mosaïque du tabac (TMV), dont le manteau protéique peut s'auto-assembler en un co-assemblage coopératif avec de l'ARN, a inspiré notre groupe pour concevoir un virus artificiel à base de cyclodextrines (CDs). Notre groupe a synthétisé une CD cationique portant un pont ammonium et sur le côté duquel est fonctionnalisé un groupement ada
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34

Dubald, Marion. "Development of antibiotic-based ophthalmic preparations for the treatment of local infections." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1201.

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Depuis ces dernières décennies, l'administration ophtalmique est devenue une voie privilégiée des molécules en vue d'une action locale. La sécurité, l'efficacité et l'acceptabilité de ces médicaments imposent une formulation stérile et facilement applicable pour l'amélioration de l'observance du patient. L'objectif de ce travail a été de développer une forme ophtalmique topique efficace, facilement applicable et contenant un principe actif (PA) d'intérêt. Les études d'encapsulation du PA dans des particules de polymères en vue de sa protection mettent en évidence la difficulté de formuler des
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35

Antoniuk, Iurii. "Elaboration de nanoparticules auto-assemblées par interaction hote-invité." Thesis, Paris Est, 2016. http://www.theses.fr/2016PESC1082/document.

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Ce travail de thèse concerne le développement de nouvelles architectures hôte et invité à base de polysaccharide et leur application dans la conception de nanoparticules molles à structure hiérarchique et d’hydrogels supramoléculaires pour l’encapsulation et la libération de médicaments. Dans la première partie du manuscrit, nous décrivons une voie de synthèse de polymères hôtes et invités comprenant des chaînons espaceurs poly(éthylène glycol) hydrophile (PEG) entre le squelette de dextrane et soit le groupement b-cyclodextrine (bCD)(polymère hôte) ou le groupement adamantane (Ada) (polymère
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36

Burusco, Goñi Kepa Koldo. "Methodological Approach to Conformational Search. A Study Case: Cyclodextrins." Doctoral thesis, Universitat Autònoma de Barcelona, 2009. http://hdl.handle.net/10803/3296.

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No és difícil trobar exemples que mostrin la inqüestionable importància de la estereoquímica en temes com la salut o l'economia: D'una banda, la quiralitat és tristament ben coneguda a causa del desastre de la Talidomida. Per altra banda, varem trobar recentment un altre exemple no menys important dins el camp de les conformacions de macromolècules: La Malaltia de Creutzfeld-Jacob. Per això, creiem que és rellevant examinar amb més detall aquells temes relacionats amb els estudis conformacionals.<br/>A la present Tesi Doctoral es proposa un procés en dues etapes per a estudiar espais conformac
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37

Mokhtar, Mohd Noriznan. "Biocatalytic Production, Preparation and Characterization of Large-ring Cyclodextrins." Doctoral thesis, Universitätsbibliothek Chemnitz, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-200900431.

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Abstract (sommario):
Cyclodextrins (CD) are cyclic oligosaccharides composed of six to more than sixty glucose units. Large-ring cyclodextrins (LR-CD) are novel CD comprised of more than eight glucose units with cavity structures and sizes different from that of commercially available CD<sub>6</sub> – CD<sub>8</sub>. LR-CD may offer unique molecular recognition properties and can be produced biocatalytically from starch using cyclodextrin glucanotransferase (CGTase, E.C. 2.4.1.19) in a short reaction time. LR-CD were isolated from glucose, CD<sub>6</sub> – CD<sub>8</sub> and other compounds by complexation of CD<s
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38

Ghadiali, Delna. "Aminolysis of the 4-acetoxybenzoate anion catalysed by cyclodextrins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0020/MQ54292.pdf.

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39

El-Hadad, Omar. "Effects of Cyclodextrins on the Kinetics of Emulsion Polymerisation." Thesis, University of Canterbury. Chemistry, 2009. http://hdl.handle.net/10092/4013.

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Cyclodextrins (CD) are semi-natural oligosaccharides composed of a number of D-glucose units. They are produced from renewable resources, and have been found to be of catalytic effect for the emulsion polymerization of many monomers. Using monomers whose emulsion polymerization kinetics have been thoroughly studied, this research analyses the effect of CD on the entry and exit rate coefficients for the emulsion polymerization of styrene, and the entry and termination rate coefficients for the emulsion polymerization of MMA. Throughout the course of the work, CD was found to have a positive im
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40

Faiz, Jonathan Antony. "Directional molecular wires constructed from photo- and electroactive cyclodextrins." Thesis, University of Birmingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419740.

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41

Boodhoo, Kishore. "Functionalised cyclodextrins for multi-metallic assemblies : towards metal extraction." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273554.

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42

Shankland, N. "B-cyclodextrins : Characterisation and use in topical semi-solids." Thesis, University of Strathclyde, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382494.

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43

Tahanpesar, Elham. "Studies of the synthesis of cyclodextrins with novel stereochemistry." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54588/.

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Abstract (sommario):
Proton-deuterium exchange of the carbinol hydrogens of gluco-, manno- and galacto-methyl- ot-D-pyranosides with deuterium oxide catalysed by ultrasonicated Raney nickel had low regioselectivity. 4,6-0-Benzylidene-methyl-cc-D-glucopyranoside underwent deuteration at C- 2 and C-3 and cleavage of the benzylidene group, whereas 4,6-O-isopropylidene-methyl-a-D- glucopyranoside was deuterated exclusively at C-2 (2H-NMR), which provides a rapid and economical route to 2- 2Hi -methyl-a-D-glucopyranoside. The diol moiety of 4,6-0-benzylidene-methyl-a-D-glucopyranoside was cleaved under aqueous (sodium
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44

Dodds, Devric Reginald. "Physicochemical study of inclusion of drug molecules in cyclodextrins." Doctoral thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/9721.

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Includes bibliographical references.<br>Inclusion of drug molecules in cyclodextrins can significantly improve various aspects of their performance and has resulted in the use of cyclodextrins (CDs) for a wide variety of pharmaceutical applications. Consequently, the cyclodextrin inclusion of drugs has received great interest in the pharmaceutical and chemical fields. For this study the inclusion of nine pharmaceutical drugs with CDs was investigated in the solid state. The objectives of the study were i.) the preparation, ii.) determination of the chemical composition, iii.) analysis of therm
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45

Pais, Joana Margarida Mosquito. "Cyclodextrins inclusion to stabilise multicomponent guests of plant origin." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22418.

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Mestrado em Bioquímica - Bioquímica Alimentar<br>A inclusão em ciclodextrinas (CDs) de hóspedes multi-componente, tais como óleos essenciais e extratos de plantas, é um tema atual e útil para uma série de aplicações nas indústrias alimentar, cosmética e farmacêutica. No presente trabalho foram estudados dois destes sistemas, tendo por hóspedes o óleo essencial de Cistus ladanifer e uma mistura de gingerois extraídos de rizoma fresco de gengibre. A composição do óleo essencial de C. ladanifer foi estudada por GC-MS, tendo-se identificado 94,3% dos seus componentes e determinado a massa molecul
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46

Cooper, Andrew Donovan. "Resolution of enantiomers using cyclodextrins in NMR and HPLC." Thesis, University of Bath, 1991. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292808.

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47

Kluzek, Monika. "Lipid membrane alteration under exposure to alpha-cyclodextrins and pH-responsive pseudopeptide polymers." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAE045/document.

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Le développement de nanotransporteurs basés sur des lipides, des polymères et des nanoparticules avec des propriétés «sur mesure» pour augmenter l’efficacité de médicaments, fait l’objet de recherches intensives. Toutefois, la physico-chimie subtile des intéractions polymères-lipides and nanoparticules-lipides présente encore de larges domaines mal compris et de nombreuses questions sans réponse. Ce projet de recherche doctoral utilise des techniques de visualisation (Cryo-MET, LSCM), et de caractérisation (ITC, DSC, SAXS, SANS, QCM-D) avancées pour obtenir des informations nouvelles sur les m
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48

Anil, Gunaratne D. M. "Physical and chemical modification of some cereal, tuber and root starches and the roles of{221}-cyclodextrin as a starch modifyingagent." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37752753.

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49

Ndlebe, Vuyelwa Jacqueline. "Thermal and photostability studies of triprolidine hydrochloride and its mixtures with cyclodextrin and glucose." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1005052.

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Triprolidine hydrochloride (C₁₉H₂₂N₂.HCl.H₂O) (TPH) is a well-known antihistamine drug. It melts between 118°C and 122°C and the amount of water present is 4.5 mass percent. TPH is reported as being photosensitive and must be stored in sealed, light-tight containers. The thermal stabilities of TPH and of 1:1 molar and 1:1 mass ratio physical mixtures of TPH with beta-cyclodextrin (BCD) and with glucose have been examined using DSC, TG and TG-FTIR, complemented by X-ray powder diffraction (XRD) and infrared spectroscopic (IR) studies. Thermal studies of the solid TPH/BCD mixtures indicated that
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Gramage-Doria, Rafael. "Large cavity cyclodextrin-based macrocyclic ligands : synthesis, coordination and catalytic properties." Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00767168.

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Cyclodextrins (CDs) are cyclic oligosaccharides of various sizes containing several α-(1→4)-linked D-(+)- glucopyranose units. The commercially available ones comprise six, seven or eight glucose units, named respectively α-CD, β-CD and γ-CD. Their truncated cone-like and well-defined cavity are particularly attractive for the encapsulation of a variety of substrates. As such, they found numerous applications in many areas of chemistry. A recent development, from which the present work is inspired, consisted in covalently linking transition metals to CD cavities in order to perform and study c
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