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Letteratura scientifica selezionata sul tema "Degradation metabolites"

Autore: Grafiati

Pubblicato: 10 agosto 2024

Ultima modifica: 31 luglio 2025

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Articoli di riviste sul tema "Degradation metabolites"

Xia, Chaoran, Qiyuan Tian, Lingyu Kong, et al. "Metabolomics Analysis for Nitrite Degradation by the Metabolites of Limosilactobacillus fermentum RC4." Foods 11, no. 7 (2022): 1009. http://dx.doi.org/10.3390/foods11071009.

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Nitrite (NIT), a commonly used food additive, especially in pickled and cured vegetables and meat products, might cause acute and chronic diseases. Fermentation with lactic acid bacteria (LAB) is an effective method for degrading NIT and improving the flavor of pickled and cured foods. In this study, Limosilactobacillus fermentum (L. fermentum) RC4 with a high NIT degradation ability was found to degrade NIT in a new manner when compared with reported enzymatic and acid degradation, namely, metabolite degradation during fermentation in MRS broth, which shows a synergistic effect with acid to i

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Shen, C. F., J. A. Hawari, G. Ampleman, S. Thiboutot, and S. R. Guiot. "Origin ofp-cresol in the anaerobic degradation of trinitrotoluene." Canadian Journal of Microbiology 46, no. 2 (2000): 119–24. http://dx.doi.org/10.1139/w99-124.

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p-Cresol was repeatedly detected as a trace metabolite in anaerobic slurry reactors treating 2,4,6-trinitrotoluene (TNT)-contaminated soils. This study shows that p-cresol was not a metabolite of the anaerobic degradation of TNT, by using a combination of analytical techniques and13C-labelled TNT. Instead, p-cresol, an intermediate in the degradation pathway of some amino acids, was shown to be inhibited by TNT and its metabolites. The range and persistence of inhibition to p-cresol microbial degradation decreased with the level of amino-substitution of the derivatives. This explains why p-cre

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Carone, F. A., M. A. Stetler-Stevenson, V. May, A. LaBarbera, and G. Flouret. "Differences between in vitro and in vivo degradation of LHRH by rat brain and other organs." American Journal of Physiology-Endocrinology and Metabolism 253, no. 3 (1987): E317—E321. http://dx.doi.org/10.1152/ajpendo.1987.253.3.e317.

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Homogenates of brain, pituitary, liver, lung, ovary, and testes were incubated with [pyro Glu1-3,4-3H]luteinizing hormone-releasing hormone ([3H]LHRH), and the profiles of metabolites generated as a function of time were determined. After 5 min of incubation, 5 was the predominant metabolite in most homogenates. Although the profiles of metabolites varied at different time intervals, metabolites 2, 3, 4, and 5, and in some instances 7 and 9, appeared to form simultaneously and were detectable at 10 min. Neither metabolite 6 nor other larger metabolites formed initially as dominant degradation

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Kar, Soumya, Marinus te Pas, Leo Kruijt, Jacques Vervoort, Alfons Jansman, and Dirkjan Schokker. "Sanitary Conditions on the Farm Alters Fecal Metabolite Profile in Growing Pigs." Metabolites 12, no. 6 (2022): 538. http://dx.doi.org/10.3390/metabo12060538.

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The aim of this study was to use fecal metabolite profiling to evaluate the effects of contrasting sanitary conditions and the associated subclinical health status of pigs. We analyzed fecal metabolite profiles by nuclear magnetic resonance (1H NMR) from pigs aged 14 and 22 weeks. Pigs kept under low and high sanitary conditions differed in fecal metabolites related to the degradation of dietary starch, metabolism of the gut microbiome, and degradation of components of animal (host) origin. The metabolites that differed significantly (FDR < 0.1) were from metabolic processes involved in eit

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Wang, Qinghong, Siyu Li, Xin Wang, Zhuoyu Li, Yali Zhan, and Chunmao Chen. "Efficient Degradation of 4-Acetamidoantipyrin Using a Thermally Activated Persulfate System." Sustainability 14, no. 21 (2022): 14300. http://dx.doi.org/10.3390/su142114300.

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The extensive use of pharmaceuticals and personal care products (PPCPs) causes high concentrations of pharmaceutical metabolites to exist in aquatic environments. Though the removal of parent PPCPs has raised concerns, the degradation of pharmaceutical metabolites was rarely investigated. In this study, the degradation of 4-acetylaminoantipyrine (4-AAA), a typical dipyrone metabolite frequently detected worldwide in surface water and wastewater, was initially studied using persulfate (PDS)-based advanced oxidation processes (AOPs). Compared with commonly used activation methods of alkali, ultr

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Hong, Junting, Nadia Boussetta, Gérald Enderlin, Nabil Grimi, and Franck Merlier. "Real-Time Monitoring of the Atrazine Degradation by Liquid Chromatography and High-Resolution Mass Spectrometry: Effect of Fenton Process and Ultrasound Treatment." Molecules 27, no. 24 (2022): 9021. http://dx.doi.org/10.3390/molecules27249021.

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High resolution mass spectrometry (HRMS) was coupled with ultra-high-performance liquid chromatography (uHPLC) to monitor atrazine (ATZ) degradation process of Fenton/ultrasound (US) treatment in real time. Samples were automatically taken through a peristaltic pump, and then analysed by HPLC-HRMS. The injection in the mass spectrometer was performed every 4 min for 2 h. ATZ and its degradation metabolites were sampled and identified. Online Fenton experiments in different equivalents of Fenton reagents, online US experiments with/without Fe2+ and offline Fenton experiments were conducted. Hig

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Chen, Xiao-Jun, Zhi-Yuan Meng, Li Ren, et al. "Determination and Safety Assessment of Residual Spirotetramat and Its Metabolites in Amaranth (Amaranthus tricolor) and Soil by Liquid Chromatography Triple-Quadrupole Tandem Mass Spectrometry." Journal of AOAC INTERNATIONAL 101, no. 3 (2018): 848–57. http://dx.doi.org/10.5740/jaoacint.17-0216.

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Abstract With the purpose of guaranteeing the safe use of spirotetramat and preventing its potential health threats to consumers, a QuEChERS extraction method coupled with LC triple-quadrupole tandem MS was applied in this study to determine residual spirotetramat metabolites in different tissues of amaranth (Amaranthus tricolor) and in soil. The results indicate that the spirotetramat degraded into different types of metabolites that were located in different tissues of amaranth and in soil. B-keto, B-glu, and B-enol were the three most representative degradation products in the leaf of amara

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Wetzstein, Heinz-Georg, Marc Stadler, Hans-Volker Tichy, Axel Dalhoff, and Wolfgang Karl. "Degradation of Ciprofloxacin by Basidiomycetes and Identification of Metabolites Generated by the Brown Rot FungusGloeophyllum striatum." Applied and Environmental Microbiology 65, no. 4 (1999): 1556–63. http://dx.doi.org/10.1128/aem.65.4.1556-1563.1999.

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ABSTRACT Ciprofloxacin (CIP), a fluoroquinolone antibacterial drug, is widely used in the treatment of serious infections in humans. Its degradation by basidiomycetous fungi was studied by monitoring14CO2 production from [14C]CIP in liquid cultures. Sixteen species inhabiting wood, soil, humus, or animal dung produced up to 35% 14CO2 during 8 weeks of incubation. Despite some low rates of14CO2 formation, all species tested had reduced the antibacterial activity of CIP in supernatants to between 0 and 33% after 13 weeks. Gloeophyllum striatum was used to identify the metabolites formed from CIP

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Hosseini, Parastou Khalessi, and Sonia Michail. "COMPARING THE GUT METABOLOMIC PROFILES IN HISPANIC AND NON-HISPANIC PEDIATRIC ULCERATIVE COLITIS PATIENTS." Inflammatory Bowel Diseases 28, Supplement_1 (2022): S67. http://dx.doi.org/10.1093/ibd/izac015.109.

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Abstract BACKGROUND Diagnosis of ulcerative colitis (UC), a subgroup of inflammatory bowel disease (IBD), is frequently overlooked among the Hispanic population. Although previously thought to impact predominantly white populations, epidemiological studies have shown an increased incidence of UC among Hispanics. Other studies have also noted variations in disease phenotype when comparing Hispanic UC patients to non-Hispanic patients. These variations could be linked to differences in the gut microbiome and shifts in the metabolomic profile. This study aims to compare the profiles of Hispanic U

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Urbaniak, Magdalena, Elżbieta Mierzejewska, and Maciej Tankiewicz. "The stimulating role of syringic acid, a plant secondary metabolite, in the microbial degradation of structurally-related herbicide, MCPA." PeerJ 7 (April 10, 2019): e6745. http://dx.doi.org/10.7717/peerj.6745.

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The ability of microorganisms to degrade xenobiotics can be exploited to develop cost-effective and eco-friendly bioremediation technologies. Microorganisms can degrade almost all organic pollutants, but this process might be very slow in some cases. A promising way to enhance removal of recalcitrant xenobiotics from the environment lies in the interactions between plant exudates such as plant secondary metabolites (PSMs) and microorganisms. Although there is a considerable body of evidence that PSMs can alter the microbial community composition and stimulate the microbial degradation of xenob

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Tesi sul tema "Degradation metabolites"

Nalli, Sandro. "Biological degradation of plasticizers and their metabolites." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85630.

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Plasticizers are widely used as additives for the production of PVC and other types of plastics. They have been observed to leach out of the solid matrix over the course of the lifetime of the finished product. These compounds have now been observed across the globe and in different environments. The main focus of this work is the study of the interactions of industrial plasticizers with soil microorganisms including bacteria, yeast and fungi.<br>This research is concerned with the microbial degradation of plasticizers such as di-2-ethylhexyl phthalate (DEHP) and di-2-ethylhexyl adipate

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Horn, Owen. "Environmental Contamination by Metabolites of Microbial Degradation of Plasticizers." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=92140.

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Earlier work with pure cultures has shown that the interaction of microbes with plasticizers leads to the formation ofmetabolites including 2-ethylhexanol and 2ethylhexanoic acid that resist further degradation. The same studies have shown that these compounds exhibit acute toxicity. This work has shown that the ability of soil micro-organisms to produce these metabolites from the degradation ofplasticizers is a general phenomenon. It was also found that the ability of soil organisms to degrade 2ethylhexanoic acid does not seem to be as common. Taken together, it would be expected that partial

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Long, Sarah Ann. "Studies of fungal natural products and the degradation of A- and SS-trenbolone." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/1356.

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Edwards, Michael. "Biological activity of anthocyanins and their phenolic degradation products and metabolites in human vascular endothelial cells." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/50546/.

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Human, animal, and in vitro data indicate significant vasoprotective activity of anthocyanins. However, few studies have investigated the activity of anthocyanin degradation products and metabolites which are likely to mediate bioactivity in vivo. The present thesis therefore examined the vascular bioactivity in vitro of anthocyanins, their phenolic degradants, and the potential for interactions between dietary bioactive compounds. Seven treatment compounds (cyanidin-, peonidin-, petunidin- & malvidin-3-glucoside, and protocatechuic, vanillic, and syringic acid) and two treatment combinations

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Afsarmanesh, Tehrani Rouzbeh. "AEROBIC BACTERIAL DEGRADATION OF HYDROXYLATED PCBs: POTENTIAL IMPLICATIONS FOR NATURAL ATTENUATION OF PCBs." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/216532.

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Civil Engineering<br>Ph.D.<br>Polychlorinated biphenyls (PCBs) are toxic and persistent chemicals that have been largely dispersed into the environment. The biological and abiotic transformations of PCBs often generate hydroxylated derivatives, which have been detected in a variety of environmental samples, including animal tissues and feces, water, and sediments. Because of their toxicity and widespread dispersion in the environment, hydroxylated PCBs (OH-PCBs) are today increasingly considered as a new class of environmental contaminants. Although PCBs are known to be susceptible to microbia

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Mardal, Marie [Verfasser]. "Studies on the biotransformation/degradation pathways of drugs of abuse and their main human metabolites in wastewater / Marie Mardal." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2017. http://d-nb.info/1227925484/34.

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CANAVESI, ROSSANA. "Chemical and metabolic stability studies of propargylamine-containing drugs." Doctoral thesis, Università del Piemonte Orientale, 2016. http://hdl.handle.net/11579/115197.

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McClean, Stephen. "An investigation of modern analytical techniques for the identification and determination of selected drugs and pollutants, their degradation products and metabolites." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322413.

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Lentola, Andrea. "Systemic insecticides, their degradation products and metabolites in the environment. Quantification methodologies in environmental samples relevant for toxicological and ecotoxicological studies." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3427171.

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Systemic insecticides are widely used for pests control and their success is due to their ability of protect the whole plant from roots to the upper leaf. In particular, seeds coating technique is very popular and it is applied to many crops (e.g. corn). However, the use of high amount of Active Ingridient (AI) for seeds coating is causing concern about negative effects to non-target animals. Pollinators insects are exposed to contaminated pollen and nectar, but also herbivore insects are exposed through contaminated leaf. In addition, these insecticides can leach from fields and contaminate

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Minetto, Luciane. "Antibióticos macrolídeos: determinação e identificação de metabólitos e subprodutos de degradação em efluente hospitalar." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/4262.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Macrolide antibiotics are an important group of prescription drugs; as a consequence of the large and continuous use, they are commonly found in the environment. In the present study, it was developed and optimized a chromatographic method to assess the occurrence of macrolide antibiotics Azithromycin, Clarithromycin, Erythromycin and Roxithromycin in the effluent of the University Hospital of Santa Maria, in two sampling points, by applying high performance liquid chromatography coupled to mass detection with quadrupole ion trap

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Libri sul tema "Degradation metabolites"

McClean, Stephen. An investigation of modern analytical techniques for the identification and determination of selected drugs and pollutants, their degradation products and metabolites. The Author], 1999.

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Ratledge, Colin. Biochemistry of microbial degradation. Springer, 2011.

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Ratledge, Colin. Biochemistry of Microbial Degradation. Springer London, Limited, 2012.

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Ratledge, Colin. Biochemistry of microbial degradation. Springer, 2012.

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Capitoli di libri sul tema "Degradation metabolites"

Lerch, Robert N., William W. Donald, Yong-Xi Li, and Eugene E. Alberts. "Hydroxylated Atrazine Degradation Products in a Small Missouri Stream." In Herbicide Metabolites in Surface Water and Groundwater. American Chemical Society, 1996. http://dx.doi.org/10.1021/bk-1996-0630.ch019.

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Roberts, Clive R., John S. Mort, and Peter J. Roughley. "Degradation of the Proteoglycans of Human Articular Cartilage by Reactive Oxygen Metabolites." In Oxygen Radicals in Biology and Medicine. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5568-7_53.

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Felix, A. M., T. Lambros, E. P. Heimer, et al. "Degradation of growth hormone releasing factor in aqueous solution: Isolation and characterization of major metabolites." In Peptides 1990. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3034-9_303.

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Christoph, N., M. Geßner, T. J. Simat, and K. Hoenicke. "Off-Flavor Compounds in Wine and Other Food Products Formed By Enzymatical, Physical, and Chemical Degradation of Tryptophan and its Metabolites." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4709-9_85.

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Verdini, Antonio S. "Biological activities of thymopentin, tuftsin and neurotensin(8–13) are profoundly influenced by metabolites resulting from enzymatic degradation of their retro-inverso analogues." In Peptides. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_4.

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Fontana, Francesco, and Giampaolo Campana. "Per- and Polyfluoroalkyl Substances: An Environmental Challenge." In Lecture Notes in Mechanical Engineering. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-77429-4_88.

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AbstractPer- and poly-fluoroalkyl substances are a group of synthetic aliphatic compounds containing one or more perfluoroalkyl moieties (CnF2n + 1-). Due to their unique surface-active properties and high chemical and thermal stability, they are used in various consumer products such as cosmetics, food packaging, furnishings, and textiles. Their use dates back to the 1940s. Despite their peculiar performances, recent scientific works investigate their sustainability and safety deriving from environmental ubiquity, persistence and bioaccumulation. Indeed, these chemicals are not metabolized in

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Warriner, Keith, and Svetlana Zivanovic. "Microbial Metabolites in Fruits and Vegetables." In Produce Degradation. CRC Press, 2005. http://dx.doi.org/10.1201/9781420039610.ch17.

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Mazza, Felipe Cury, Nilo Antônio de Souza Sampaio, and Carin Von Mühlen. "Historical evolution of chromatographic methods for the determination of endosulfan and its metabolites in water samples." In Uniting Knowledge Integrated Scientific Research For Global Development V.2. Seven Editora, 2024. http://dx.doi.org/10.56238/sevened2024.018-049.

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Endosulfan is a highly toxic, broad-spectrum insecticide. Alpha-endosulfan, Betha-endosulfan, and their metabolites are on the Stockholm Convention on Persistent Organic Pollutants list. Endosulfan metabolites exhibit a wide range of chemical characteristics resulting in hard work for chemical analysts to specify all known degradation products of this insecticide in environmental matrices. This manuscript reviews the evolution of analytical methods related to the determination of endosulfan and its metabolites in environmental matrices. Specific metabolites, such as endosulfan alcohol, have ve

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Pratap Singh, Aditya, Ponaganti Shiva Kishore, Santanu Kar, and Sujaya Dewanjee. "Secondary Metabolites of Brassica juncea (L.) Czern and Coss: Occurence, Variations and Importance." In Brassica - Recent Advances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107911.

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There are numerous secondary plant metabolites found in the crop B. juncea, especially glucosinolates. Isothiocyanates, the by-products of glycosinolate breakdown, are beneficial to human health. A number of studies have also called attention to phenolic compounds and carotenoids, both well known for their anti-oxidant properties. A notable feature is that the profiles and concentrations of secondary plant metabolites vary greatly between varieties and that genetic factors are thought to be the most significant factors. In addition, environmental and agronomic factors have also been noted to c

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McKee, Trudy, and James R. McKee. "Nitrogen Metabolism II: Degradation." In Biochemistry. Oxford University Press, 2020. http://dx.doi.org/10.1093/hesc/9780190847685.003.0015.

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This chapter deals with the metabolism of nitrogen-containing molecules, such as proteins and nucleic acids, that differs significantly from that of carbohydrates and lipids. Whereas the latter molecules can be stored and mobilized when needed for biosynthetic reactions or for energy generation, there is no nitrogen-storing molecule. The chapter elaborates how organisms must constantly replenish their supply of usable nitrogen to replace organic nitrogen that is lost in catabolism. It mentions the turnover of protein and nucleic acids, which is one of the most obvious aspects of cellular renov

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Atti di convegni sul tema "Degradation metabolites"

Andrew, B. E. "Monitoring of Microbiological Metabolites by Ion Chromatography." In CORROSION 1988. NACE International, 1988. https://doi.org/10.5006/c1988-88089.

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Abstract Ion chromatography is a useful analytical technique for obtaining quantitative data with respect to microbiological metabolites on surfaces and in bulk solution. Case histories include anaerobic degradation of nitrite in bulk solution and on steel surfaces, resulting in microbiologically induced corrosion. Aerobic degradation of nitrite in a cooling water system will illustrate the importance of selecting appropriate simulation conditions. Short-chain fatty acids in emulsion coolants are generated by microbiological action, and can contribute to product corrosion. These metabolites ar

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Videla, H. A., P. S. Guiamet, S. DoValle, and E. H. Reinoso. "Effects of Fungal and Bacterial Contaminants of Kerosene Fuels on the Corrosion of Storage and Distribution Systems." In CORROSION 1988. NACE International, 1988. https://doi.org/10.5006/c1988-88091.

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Abstract The electrochemical behavior of pure aluminum, 2024 alloy and mild steel have been studied in the presence of several species of fungi and bacteria isolated from kerosene fuels storage and distribution systems. Microbial growth facilitates passivity breakdown mainly through the action of organic acidic metabolites derived from hydrocarbon degradation. Their corrosive effect depends on the pH and electrolyte composition of the medium, especially with reference to chloride and nitrate levels. Microbial adhesion to the metal surface enhances metal dissolution. The metabolic activities of

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Púa, Lizeth Gutiérrez, Virginia Paredes Méndez, Ana María Fonseca Reyes, Juan Carlos Rincón Montenegro, and Lily Margareth Payares. "Enhanced Corrosion Resistance and Biocompatibility of Pure Magnesium Modified by Calcium Phosphate / Biomass of Chlorella Sp. Coating for Orthopedic Applications." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-18513.

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Extended Abstract Biomedical metallic materials can be harmful to the human body in the long term due to the release and accumulation of metallic particles resulting from the degradation and corrosion of the material, a consequence of the wear suffered by the implant. Therefore, biodegradable materials have been studied that reduce the risk to health and the need for a second surgical intervention to remove the implant when the tissue is regenerated. Magnesium alloys are possible candidates as degradable biomaterials for temporary implants in various specialties such as traumatology, cardiolog

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Statsyuk, N. V., L. A. Shcherbakova, O. D. Mikityuk, T. A. Nazarova, and V. G. Dzhavakhiya. "Mycotoxin degradation by microbial metabolites." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.234.

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Extracellular metabolites of Gliocladium roseum GRZ7 are able to destroy aflatoxin B1 and zearalenone (by 61.9 and 68%, respectively). The determined optimum pH and temperature confirm the enzymatic nature of these metabolites.

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Zang, Shuyan, and Panpan Li. "Influence of Surfactant-Tween80 on Degradation of Benzo(a)Pyrene and Its Accumulated Metabolites by Bacillus-07." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5517098.

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Dekić, Milan S., and Amina M. Gusinac. "THE AUTOLYSIS PRODUCTS OF GLUCOSINOLATES IN „LEPIDIUM CAMPESTRE“ (L.) W. T. AITON (BRASSICACEAE)." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.367d.

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Plant samples of Lepidium campestre (L.) W. T. Aiton (pepperwort) were analyzed in detail by GC and GC-MS. The analysis of the autolysates obtained from inflorescences, stems, leaves, and underground parts and the essential oil obtained by hydrodistillation allowed the identification of a series of glucosinolate degradation products, mainly isothiocyanates and nitriles. Besides previously identified ones in this species, the analyses resulted in the identification of degradation metabolites identified in pepperwort for the first time, and suggested the presence of heptyl glucosinolate, 3- phen

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Savanović, Jovana, Dragana Popović, Andrija Vučetić, Tatjana Ćurčić, and Dragana Despot. "Ecotoxicological effect of diflubenzuron." In 36. Savetovanje dezinfekcija, dezinsekcija i deratizacija jedan svet - jedno zdravlje, Vrnjačka Banja, hotel "Vrnjačke Terme", 28-31.maj 2025.godine. Srpsko veterinarsko društvo, 2024. https://doi.org/10.5937/ddd25140s.

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Diflubenzuron is an insecticide from the group of insect growth regulators, widely used in agriculture and forestry for pest control. Its application can have negative effects on non-target organisms and ecosystems. In the environment, diflubenzuron degrades through hydrolysis, photodegradation, and microbial activity, producing 4-chloroaniline (4-CA), a toxic and persistent byproduct. In aquatic ecosystems, diflubenzuron disrupts chitin synthesis, endangering crustaceans, mollusks, and planktonic organisms, whose growth and development depends on this polysaccharide. While it does not directl

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Lungu, Andrei. "Cultivation attempts of Saccharopolyspora spinosa on liquid medium." In Scientific International Symposium “Advanced Biotechnologies - Achievements and Prospects” (VIth Edition). Institute of Genetics, Physiology and Plant Protection, 2022. http://dx.doi.org/10.53040/abap6.2022.61.

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In the last ﬁfty years, pesticides of chemical origin were very actively used, which undoubte-dly led to an increase in agricultural production, both quantitatively and qualitatively, and inﬂuen-ced the spread in certain areas and of diﬀerent crops, which were more diﬃcult before. But people started using these products without examining their impact on the environment and without taking into account that other generations will also need this habitat to develop. Use of pesticides contrary to recommendations led to air, water and soil pollution. Residues generated during the degradation of many

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Brito, Jordana T., Lucas H. Martorano, Ana Carolina F. de Albuquerque, et al. "ESPECTROSCOPIA COMPUTACIONAL APLICADA AO REASSINALAMENTO ESTRUTURAL DE MOLÉCULAS QUIRAIS: HELIANNUOL L." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol202025.

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In the past, structure determination of natural products was an arduous process depending almost entirely on chemical synthesis, mainly by derivatization and degradation processes, taking years of effort. Recently, structural elucidation of natural products has undergone a revolution. Nowadays, with the combined use of different advanced spectroscopic methods, it became possible to completely assign the structure of natural products using small amounts of sample. However, despite the extraordinary ongoing advances in spectroscopy, the mischaracterization of natural products has been and remain

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Benedetti, Rafael, Frieda Saicla Barros, Diego Rinaldi Pavesi Nicollete, and Marcus Figueredo. "Quantificação de Bilirrubina total por Metodologia de Cromatografia de Fluxo lateral." In X-Meeting / BSB 2023. Even3, 2023. http://dx.doi.org/10.29327/1331270.643318.

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Bilirubin is a pigment metabolite that serves as a liver marker. Could be used to evaluate liver function. This metabolite is coming from Red blood cell degradation, associated with direct liver damag

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Rapporti di organizzazioni sul tema "Degradation metabolites"

KHASAEVA, Igor PARSHIKOV, and ZARAISKY. DEGRADATION OF 4-METHYLPYRIDINE BY ARTHROBACTER SP. Intellectual Archive, 2020. http://dx.doi.org/10.32370/iaj.2462.

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In the process of degradation of 4-methylpyridine by bacterium Àrthrobacter sp. KM-4MP were isolated two metabolites and identified as 4-methylpyridin-2-ol and 8-hydroxy-4-methylidene-1Hcyclopenta[ 1,2-b:3,4-c’]dipyridine-2,3,5,7(4H,6H)-tetrone.

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Khasaeva, Fatima, Igor Parshikov, and Evgeny Zaraisky. Degradation of 2,6-dimethylpyridine by Arthrobacter crystallopoietes. Intellectual Archive, 2020. http://dx.doi.org/10.32370/iaj.2463.

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Degradation of pyridines in waste water is an important issue for chemical and pharmaceutical industries. The biodegradation of 2,6-dimethylpyridine was investigated by the bacterium Arthrobacter crystallopoietes KM-4, which resulted in the formation of three metabolites: 2,6-dimethylpyridin-3-ol, 2,6-dimethylpyridin- 3,4-diol, and 2,4-dioxopentanoic acid.

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Amir, Rachel, David J. Oliver, Gad Galili, and Jacline V. Shanks. The Role of Cysteine Partitioning into Glutathione and Methionine Synthesis During Normal and Stress Conditions. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699850.bard.

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The objective of this research is to study the nature of the competition for cysteine (Cys), the first organic sulfur-containing compound, between its two main metabolites, glutathione (GSH) and methionine (Met). GSH plays a central role in protecting plants during various stresses, while Met, an essential amino acid, regulates essential processes and metabolites in plant cells through its metabolite S-adenosyl-Met. Our results, which are based on flux analysis and measurements of Met- metabolites, show that the flux towards Met synthesis is high during non-stress conditions, however the flux

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Borch, Thomas, Yitzhak Hadar, and Tamara Polubesova. Environmental fate of antiepileptic drugs and their metabolites: Biodegradation, complexation, and photodegradation. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597927.bard.

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Many pharmaceutical compounds are active at very low doses, and a portion of them regularly enters municipal sewage systems and wastewater-treatment plants following use, where they often do not fully degrade. Two such compounds, CBZ and LTG, have been detected in wastewater effluents, surface waters, drinking water, and irrigation water, where they pose a risk to the environment and the food supply. These compounds are expected to interact with organic matter in the environment, but little is known about the effect of such interactions on their environmental fate and transport. The original o

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Chamovitz, A. Daniel, and Georg Jander. Genetic and biochemical analysis of glucosinolate breakdown: The effects of indole-3-carbinol on plant physiology and development. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597917.bard.

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Genetic and biochemical analysis of glucosinolate breakdown: The effects of indole-3-carbinol on plant physiology and development Glucosinolates are a class of defense-related secondary metabolites found in all crucifers, including important oilseed and vegetable crops in the Brassica genus and the well-studied model plant Arabidopsis thaliana. Upon tissue damage, such as that provided by insect feeding, glucosinolates are subjected to catalysis and spontaneous degradation to form a variety of breakdown products. These breakdown products typically have a deterrent effect on generalist herbivor

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Wackett, Lawrence, Raphi Mandelbaum, and Michael Sadowsky. Bacterial Mineralization of Atrazine as a Model for Herbicide Biodegradation: Molecular and Applied Aspects. United States Department of Agriculture, 1999. http://dx.doi.org/10.32747/1999.7695835.bard.

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Atrazine is a broadly used herbicide in agriculture and it was used here as a model to study the biodegradation of herbicides. The bacterium Pseudomonas sp. ADP metabolizes atrazine to carbon dioxide and ammonia and chloride. The genes encoding atrazine catabolism to cyanuric acid were cloned and expressed in Escherichia coli. The genes were designated atzA, atzB and atzC. Each gene was sequenced. The enzyme activities were characterized. AtzA is atrazine chlorohydrolase which takes atrazine to hydroxyatrizine. AtzB is hydroxyatrazine N-ethylaminohydrolase which produces N-isopropylammelide an

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Cytryn, Eddie, Mark R. Liles, and Omer Frenkel. Mining multidrug-resistant desert soil bacteria for biocontrol activity and biologically-active compounds. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7598174.bard.

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Control of agro-associated pathogens is becoming increasingly difficult due to increased resistance and mounting restrictions on chemical pesticides and antibiotics. Likewise, in veterinary and human environments, there is increasing resistance of pathogens to currently available antibiotics requiring discovery of novel antibiotic compounds. These drawbacks necessitate discovery and application of microorganisms that can be used as biocontrol agents (BCAs) and the isolation of novel biologically-active compounds. This highly-synergistic one year project implemented an innovative pipeline aimed

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Carrigee, Lyndsay, Carina Jung, Matthew Carr, and Karl Indest. Bacterial remediation of microsystin-HAB toxins utilizing microcystinase (MlrA). Engineer Research and Development Center (U.S.), 2025. https://doi.org/10.21079/11681/49673.

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Microcystins are a class of hepatotoxins produced by some harmful algal bloom–associated cyanobacteria and are the most reported toxins in freshwaters. Their cyclic structure makes them resistant to conventional methods used in water treatment operations (boiling, chlorination, and UV treatment). Some bacteria can naturally degrade microcystins via the mlrABCD cluster, a pathway initiated by the primary enzyme microcystinase (MlrA). MlrA linearizes the cyclic microcystin, greatly reducing its toxicity. Protein fusion was employed to produce a recombinant MlrA enzyme fused to maltose-binding pr

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Schuster, Gadi, and David Stern. Integration of phosphorus and chloroplast mRNA metabolism through regulated ribonucleases. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7695859.bard.

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New potential for engineering chloroplasts to express novel traits has stimulated research into relevant techniques and genetic processes, including plastid transformation and gene regulation. This proposal continued our long time BARD-funded collaboration research into mechanisms that influence chloroplast RNA accumulation, and thus gene expression. Previous work on cpRNA catabolism has elucidated a pathway initiated by endonucleolytic cleavage, followed by polyadenylation and exonucleolytic degradation. A major player in this process is the nucleus-encoded exoribonuclease/polymerasepolynucle

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