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Articoli di riviste sul tema "Delirium"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

Kawaura, Takayuki, and Yasuyuki Sugatani. "Clinical Nurses’ Awareness Structure of Delirium – An Analysis of Spontaneous Utterances in a Group Interview by DEMATEL Method –." Journal of Advanced Computational Intelligence and Intelligent Informatics 18, no. 6 (2014): 1013–19. http://dx.doi.org/10.20965/jaciii.2014.p1013.

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In the 1990s, the Japanese population aged 65 and over increased to more than 14%, and Japan became an “aging society.” Now, one in five people are 65 or over (23.4%, and one in ten people are 75 or over (1.6%, meaning that Japanese society is aging substantially. The serious problems that acute hospitals now face involve complications of diseases that are typified by deliriu, and their prevention. Patients with delirium have a higher risk of falling and dying, and delirium has a negative influence on treatment and nursing as well as on a patient’s vital prognosis. However, delirium is a menta

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Emond, M., A. Nadeau, V. Boucher, et al. "MP11: Underreport of incident delirium in elderly patients treated in the emergency department." CJEM 20, S1 (2018): S44. http://dx.doi.org/10.1017/cem.2018.165.

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Introduction: It is documented that physicians and nurses fail to detect delirium in more than half of cases from various clinical settings, which could have serious consequences for seniors and for our health care system. The present study aimed to describe the rate of documented incident delirium in 5 Canadian Emergency departments (ED) by health professionals (HP). Methods: This study is part of the multicenter prospective cohort INDEED study. Patients aged 65 years old, initially free of delirium with an ED stay 8hours were followed up to 24h after ward admission. Delirium status was asses

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Falsini, Giovanni, Simone Grotti, Italo Porto, et al. "Long-term prognostic value of delirium in elderly patients with acute cardiac diseases admitted to two cardiac intensive care units: a prospective study (DELIRIUM CORDIS)." European Heart Journal: Acute Cardiovascular Care 7, no. 7 (2017): 661–70. http://dx.doi.org/10.1177/2048872617695235.

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Background: Delirium is a frequent in-hospital complication in elderly patients, and is associated with poor clinical outcome. Its clinical impact, however, has not yet been fully addressed in the setting of the cardiac intensive care unit (CICU). The present study is a prospective, two-centre registry aimed at assessing the incidence, prevalence and significance of delirium in elderly patients with acute cardiac diseases. Methods: Between January 2014 and March 2015, all consecutive patients aged 65 years or older admitted to the CICU of our institutions were enrolled and followed for 6 month

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Rood, Paul J. T., Dharmanand Ramnarain, Annemarie W. Oldenbeuving, et al. "The Impact of Non-Pharmacological Interventions on Delirium in Neurological Intensive Care Unit Patients: A Single-Center Interrupted Time Series Trial." Journal of Clinical Medicine 12, no. 18 (2023): 5820. http://dx.doi.org/10.3390/jcm12185820.

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Background: Delirium is a pathobiological brain process that is frequently observed in Intensive Care Unit (ICU) patients, and is associated with longer hospitalization as well as long-term cognitive impairment. In neurological ICU patients, delirium may be more treatment-resistant due to the initial brain injury. This study examined the effects of a multicomponent non-pharmacological nursing intervention program on delirium in neurological ICU patients. Methods: A single-center interrupted time series trial was conducted in adult neurological ICU patients at high risk for developing delirium

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Heymann, A., M. Sander, D. Krahne, et al. "Hyperactive Delirium and Blood Glucose Control in Critically Ill Patients." Journal of International Medical Research 35, no. 5 (2007): 666–77. http://dx.doi.org/10.1177/147323000703500511.

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Delirium is a common complication of critically ill patients and is often associated with metabolic disorders. One of the most frequent metabolic disorders in intensive care unit (ICU) patients is hyperglycaemia. The aim of this retrospective study of 196 adult ICU patients was to determine if there is an association between hyperactive delirium and blood glucose levels in ICU patients. Hyperactive delirium was diagnosed using the delirium detection score. Blood glucose levels were monitored by blood gas analysis every 4 h. Hyperactive delirium was detected in 55 (28%) patients. Delirious pati

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Ren, Quan, Ya-zhou Wen, Jin Wang, et al. "Elevated Level of Serum C-reactive Protein Predicts Postoperative Delirium among Patients Receiving Cervical or Lumbar Surgery." BioMed Research International 2020 (August 10, 2020): 1–8. http://dx.doi.org/10.1155/2020/5480148.

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Objective. To explore the relationship between elevated serum C-reactive protein (CRP) level and postoperative delirium (POD). Methods. 206 patients scheduled to receive cervical or lumbar vertebra surgery under general anesthesia for more than 2 hours in a single medical center were observed and analyzed. Patients’ serum CRP, delirious status (using the confusion assessment method (CAM)), and delirious score (using the memorial delirium assessment scale (MDAS)) were examined before surgery and 1-2 days after surgery. The association of a serum CRP elevation value from before to after surgery

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Adamis, D., J. Williams, K. Finn, V. Melvin, D. Meagher, and G. McCarthy. "Brain-derived Neurotrophic Factor (BDNF) Levels and Delirium." European Psychiatry 41, S1 (2017): s237. http://dx.doi.org/10.1016/j.eurpsy.2017.01.2263.

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IntroductionStudies of the association between blood BDNF levels and delirium are very few and have yielded mixed results.ObjectivesTo investigate the blood BDNF levels in the occurrence and recovery of delirium.MethodsProspective, longitudinal study. Participants were assessed twice weekly with MoCA, DRS-R98, APACHE-II. BDNF levels of the same were estimated with ELISA method. Delirium has been define as per DRS-98R (cut-off > 16) and recovery of delirium as at least two consequently assessments without delirium prior to discharge.ResultsNo differences in the levels of BDNF between those w

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Sullinger, Danine, Alexander Gilmer, Lesly Jurado, et al. "Development, Implementation, and Outcomes of a Delirium Protocol in the Surgical Trauma Intensive Care Unit." Annals of Pharmacotherapy 51, no. 1 (2016): 5–12. http://dx.doi.org/10.1177/1060028016668627.

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Background: Delirium in the critically ill is associated with increased mortality, length of stay (LOS), and prolonged cognitive dysfunction. Existing guidelines provide no recommendation for use of combination nonpharmacological and pharmacological prevention protocols or use of antipsychotic medications for the prevention or treatment of delirium. Objective: This study evaluated the impact of implementing a delirium treatment protocol on the number of delirium-free days experienced by acutely delirious patients in the surgical trauma intensive care unit (STICU). Methods: This retrospective,

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Suleman, A., J. Krakovsky, and P. Joo. "LO15: Treatment of asymptomatic bacteriuria in elderly patients with delirium: a systematic review." CJEM 20, S1 (2018): S11—S12. http://dx.doi.org/10.1017/cem.2018.77.

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Introduction: It is typical to look for UTI in delirious elderly patients, despite a high prevalence of asymptomatic bacteriuria (ASB) in this population. A common presentation of infection is delirium, which often has a non-specific and multifactorial etiology. Therefore, when bacteriuria is present with delirium in the absence of urinary symptoms, physicians prescribe antibiotics for the suspected UTI-induced delirium. We set to determine whether antibiotic treatment in the elderly presenting with delirium in the presence of ASB resulted in resolution of delirium. Methods: Literature searche

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Woodward, Jennifer, and Tru Byrnes. "A Delirium Risk Stratification Tool and Interdisciplinary Rounds to Prevent Delirium in Hospitalized Older Adults." Innovation in Aging 5, Supplement_1 (2021): 593. http://dx.doi.org/10.1093/geroni/igab046.2279.

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Abstract Delirium is a disturbance of attention accompanied by a change in baseline cognition that is commonly seen in acute care settings, and effects up to 80% of ICU patients. The development of delirium has adverse effects on patient outcomes and high health care costs. Of patients aged 65+ admitted to our hospital in 2019, non-delirious patients had a five-day length of stay (LOS) compared to a 10-14 days LOS in delirious patients. A five days LOS increase adds an additional $ 8,325 per patient for an extra annual cost of 15 million dollars. Additionally, delirium is often not recognized.

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Gupta, Kriti, Vipin Kumar Singh, and G. P. Singh. "2: Evaluation of role of exogenous melatonin in prevention of delirium in postoperative patients admitted in intensive care unit : a randomised placebo-controlled study." Indian Journal of Anaesthesia 66, Suppl 1 (2022): S68—S69. http://dx.doi.org/10.4103/0019-5049.340654.

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Background and Aims: Delirium is extremely prevalent in hospitalised patients; 37–46% of the general surgical population and in up to 87 % of patients in the intensive care unit (ICU).Melatonin – a potential agent in the management of delirium since its low plasma concentrations and altered secretion patterns have been found in the critically ill (6-sulphatoxymelatonin (MT6) in subjects’ urine). To establish the reduction in incidence of delirium [as determined by the confusion assessment method (CAM-ICU) scale], in post operative patients admitted in ICU after administration of exogenous oral

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Maldeniya, Pramudith M., and Akshya Vasudev. "Is the Concept of Delirious Mania Valid in the Elderly? A Case Report and a Review of the Literature." Case Reports in Psychiatry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/432568.

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Delirious mania has been well recognized in the published literature and in the clinic. Over the years there has been refinement of understanding of its clinical features, course, and treatment. The literature suggests that delirious mania should be considered in individuals who present with a constellation of sudden onset delirium, mania, and psychosis. However, delirious mania is not recognized under a formal classification system nor are there any formal guidelines for its treatment. We, as such, question if the concept of delirious mania in the elderly is valid. We present a case of an eld

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Ali, Mohammed, Naziya Hassan, and Duprey Robert P. "Polypharmacy Induced Delirium: A Case Report Highlighting the Importance of a Thorough Psychiatric History and Physical." Neuropsychiatry 9, no. 5 (2019): 5. https://doi.org/10.5281/zenodo.13593830.

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A combative aggressive 65 year old female was brought in to the Emergency Room (ED)after found wondering in the streets. Agitated, confused, disoriented in a delirious state,she was admitted to psychiatry for diagnostic clarification. All labs except low platelets wereWithin Normal Limits (WNL). Imaging was normal. She was not a known neuro-cognitivedisorder patient. Poly-pharmacy was ruled in as the etiology of the delirium highlighting theimportance of careful prescribing especially in older persons. Moreover, this case highlightsthe importance of having expert knowledge in (a) the prescribi

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Slor, Chantal J., Joost Witlox, Dimitrios Adamis, et al. "Predicting Delirium Duration in Elderly Hip-Surgery Patients: Does Early Symptom Profile Matter?" Current Gerontology and Geriatrics Research 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/962321.

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Background. Features that may allow early identification of patients at risk of prolonged delirium, and therefore of poorer outcomes, are not well understood. The aim of this study was to determine if preoperative delirium risk factors and delirium symptoms (at onset and clinical symptomatology during the course of delirium) are associated with delirium duration.Methods. This study was conducted in prospectively identified cases of incident delirium. We compared patients experiencing delirium of short duration (1 or 2 days) with patients who had more prolonged delirium (≥3 days) with regard to

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Sánchez Caraballo, ´Álvaro, Jorge Herrera Herrera, Néider Cárdenas Díaz, and Edison Oyola López. "Delirio en pacientes con síndrome coronario agudo en una unidad de cuidados intensivos." Revista avances en salud 3, no. 1 (2019): 26–33. http://dx.doi.org/10.21897/25394622.1763.

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El Delirio es una variación aguda del estado de conciencia, frecuente en la unidad de cuidados intensivos (UCI). Su incidencia varía ampliamente, presentando diferentes características clínicas correlacionadas. Objetivo. Determinar la incidencia de delirium en pacientes con síndrome coronario agudo (SCA) en la UCI, e identificar sus características clínicas asociadas, así como la correlación del delirio (CAM-ICU) y el grado de severidad de la enfermedad (APACHE-II). Materiales y métodos. Estudio descriptivo, prospectivo, cuantitativo. Realizado durante el cuarto bimestre del 2015. A los pacien

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Jiang, Shixie, Philip A. Efron, Esther S. Oh, and Steven T. DeKosky. "Optical Neuroimaging in Delirium." Photonics 10, no. 12 (2023): 1334. http://dx.doi.org/10.3390/photonics10121334.

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Delirium persists as the most common neuropsychiatric syndrome among medically ill hospitalized patients, yet its neural mechanisms remain poorly understood. The development of neuroimaging biomarkers has been difficult primarily due to the complexities of imaging patients experiencing delirium. Optical imaging techniques, including near-infrared spectroscopy (NIRS) and diffuse optical tomography (DOT), offer promising avenues for investigating delirium’s pathophysiology. These modalities uniquely stand out for delirium exploration due to their blend of spatiotemporal resolution, bedside appli

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Azhar, Gohar, Shakshi Sharma, Regina Gibson, Amanda Pangle, Robert Wolfe, and Jeanne Wei. "EVALUATION OF AMINO ACIDS LEVELS OF HOSPITALIZED PATIENTS WITH DELIRIUM." Innovation in Aging 7, Supplement_1 (2023): 452–53. http://dx.doi.org/10.1093/geroni/igad104.1488.

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Abstract Delirium is an acute and often fluctuating change in cognitive status characterized by disorientation, disorganized thought processes and changes in perceptual and psychomotor function. The common precipitating etiologies of delirium include any acute illnesses, infections, hospitalizations, fluid or electrolyte imbalance, or medications. Neurotransmitters are synthesized from amino acids. We hypothesized that regardless of the clinical reason for delirium, a sudden imbalance of plasma amino acids might alter the level of neurotransmitters and contribute to delirium. We measured amino

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Cheston, H., E. Miller, and S. Mufti. "120 Improving Delirium Recognition and Management Through In-Situ Simulation." Age and Ageing 50, Supplement_1 (2021): i12—i42. http://dx.doi.org/10.1093/ageing/afab030.81.

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Abstract Introduction Delirium is a common condition that is often associated with increased morbidity and mortality, longer hospital admission, and discharge to a residential or nursing home. By improving our ability to recognise and manage these patients we can intervene early to help reduce the likelihood of these outcomes. Method We organised several in-situ simulation scenarios with junior staff working on the Elderly Care Unit. The research team designed a scenario to re-create a typical delirious patient on the ward. Participants had to recognise the patient was delirious and instigate

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Émond, M., P. Voyer, R. Daoust, et al. "LO022: Incidence and impact measurement of delirium induced by ED stay - INDEED." CJEM 18, S1 (2016): S37—S38. http://dx.doi.org/10.1017/cem.2016.59.

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Introduction: Delirium is a dreadful complication in seniors’ acute care. Many studies are available on the incidence of delirium, however ED-induced delirium is far less studied. We aim to evaluate the incidence and impact of ED-induced delirium among older non-delirious admitted ED patients who have prolonged ED stays (≥ 8 hours). Methods: This prospective INDEED study phase 1 included patients recruited from 4 Canadian EDs. Inclusion criteria: 1) Patients aged 65 and over; 2) ED stay ≥ 8 hours; 3) Patient is admitted to the hospital; 4) Patient is non-delirious upon arrival and at the end o

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Kok Kendirlioglu, Burcu, Esma Corekli Kaymakci, Suat Kucukgoncu, Bugra Cetin, and Hidayet Ece Arat Celik Ece Arat Celik. "DELIRIOUS MANIA OR HYPERACTIVE DELIRIUM? A CASE REPORT." PSYCHIATRIA DANUBINA 35, no. 3 (2023): 433–35. http://dx.doi.org/10.24869/psyd.2023.433.

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Hamidović, J., L. Dostović Hamidović, S. Haskic, E. Prljača, A. Brigić, and M. Mešanović. "Etiology and pharmacological treatment of delirious syndrome." European Psychiatry 66, S1 (2023): S380. http://dx.doi.org/10.1192/j.eurpsy.2023.822.

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IntroductionPatients in psychiatric department, especially in the intensive care unit, often develop delirium syndrome, which leads to a high risk of morbidity and mortality. The etiology is multifactorial. The most common causes are alcoholism and dementia. Pharmacological treatment of delirious syndrome is the most important part of the treatment, which includes various psychopharmaceuticals that are effective both in the treatment of delirium and in improving cognitive functions. Haloperidol is the drug of first choice and from atypical antipsychotics, the most commonly used are risperidone

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Emond, M., A. Nadeau, V. Boucher, et al. "MP09: Incidence of emergency department induced delirium: a Canadian two years prospective study." CJEM 20, S1 (2018): S43. http://dx.doi.org/10.1017/cem.2018.163.

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Introduction: Prevalence and incidence of delirium in older patients admitted to acute and long-term care facilities ranges between 9.6% and 89% but little is known in the context of emergency department (ED) incident delirium. Literature regarding the incidence of delirium in the ED and its potential impacts on hospital length of stay (LOS), functional status and unplanned ED readmissions is scant, its consequences have yet to be clearly identified in order to orient modern acute medical care. Methods: This study is part of the multicenter prospective cohort INDEED study. Three Canadian EDs c

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Bergus, Katherine, Tran Bourgeois, Kelli Patterson, Dana Schwartz, Rajan Thakkar, and Renata Fabia. "68 Using the Cornell Assessment of Pediatric Delirium Score to Identify Delirium in Pediatric Burn Patients." Journal of Burn Care & Research 44, Supplement_2 (2023): S34. http://dx.doi.org/10.1093/jbcr/irad045.042.

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Abstract Introduction Delirium rates in pediatric critical care range from 18-40% and its development is associated with baseline cognitive dysfunction, primary diagnosis, and mechanical ventilation. The Cornell Assessment of Pediatric Delirium (CAPD) is a tool used to detect delirium in children of all ages, but has not been validated in burn patients. Our study aimed to use CAPD score to determine the frequency of delirium in pediatric burn patients and assess the association of delirium with burn demographics. Methods We conducted a retrospective review of patients aged 2.5 weeks to 18 year

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SARI, Neslihan, and Meryem YAVUZ VAN GİERSBERGEN. "SAĞLIK ÇALIŞANLARININ YOĞUN BAKIMLARDA DELİRYUM YÖNETİMLERİNİN İNCELENMESİ." Yoğun Bakım Hemşireliği Dergisi 27, no. 3 (2023): 128–37. http://dx.doi.org/10.62111/ybhd.1264698.

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Özet Amaç: Yoğun bakımlardaki sağlık çalışanları deliryumu tanılamada ve önlemede önemli rollere sahiptir. Bu araştırma; Yoğun bakımda çalışan hemşire ve hekimlerin deliryum yönetimleri konusunda bilgi, tutum ve uygulamalarını incelemek amacıyla tanımlayıcı tipte yapılmıştır. Yöntem: Araştırma İzmir ilinde bulunan 3 üniversite hastanesinde yürütüldü. Araştırmanın örneklemini, araştırmanın yapıldığı hastanelerin yoğun bakım ünitelerinde görev yapan ve araştırmaya katılmayı kabul eden 175 sağlık çalışanı oluşturdu. Veriler sosyodemografik özelliklerine ilişkin soru formu, deliryum il

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Sokouti, Babak. "A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes." OBM Neurobiology 09, no. 01 (2025): 1–31. https://doi.org/10.21926/obm.neurobiol.2501276.

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Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidative stress, and synaptic function. Traditional Chinese medicine (TCM) compounds we

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Martínez-Velilla, Nicolas, José G. Franco, and Clara Marina Molina Amaya. "Delirio frente a delirium." Medicina Clínica 147, no. 6 (2016): 274–75. http://dx.doi.org/10.1016/j.medcli.2016.04.005.

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Maybrier, Hannah R., Angela M. Mickle, Krisztina E. Escallier, et al. "Reliability and accuracy of delirium assessments among investigators at multiple international centres." BMJ Open 8, no. 11 (2018): e023137. http://dx.doi.org/10.1136/bmjopen-2018-023137.

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IntroductionDelirium is a common, serious postoperative complication. For clinical studies to generate valid findings, delirium assessments must be standardised and administered accurately by independent researchers. The Confusion Assessment Method (CAM) is a widely used delirium assessment tool. The objective was to determine whether implementing a standardised CAM training protocol for researchers at multiple international sites yields reliable inter-rater assessment and accurate delirium diagnosis.MethodsPatients consented to video recordings of CAM delirium assessments for research purpose

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Boettger, Soenke, Steven Passik, and William Breitbart. "Delirium superimposed on dementia versus delirium in the absence of dementia: Phenomenological differences." Palliative and Supportive Care 7, no. 4 (2009): 495–500. http://dx.doi.org/10.1017/s1478951509990502.

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AbstractObjective:To examine differences in the phenomenological characteristics of delirium superimposed on dementia compared to those observed in delirious patients without dementia, based on the rating items of the Memorial Delirium Assessment Scale (MDAS).Methods:We conducted an analysis of a prospectively collected clinical delirium database utilized to record and monitor the care of delirious patients treated at Memorial Sloan-Kettering Cancer Center (MSKCC). Sociodemographic, medical variables, and MDAS total score and individual item ratings were analyzed in respect to differences betw

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Schwartz, Thomas L., Mantosh J. Dewan, and Wendy A. Armenta. "Sustained Manic Delirium." Journal of Pharmacy Technology 16, no. 4 (2000): 147–50. http://dx.doi.org/10.1177/875512250001600409.

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Objective: To report a case of bipolar I disorder with psychotic features that resembled a sustained episode of delirium. Case Summary: A 54-year-old white woman with bipolar I disorder developed severe, sustained psychosis resembling delirium. These symptoms resolved following several pharmacologic interventions. Discussion: Manic delirium is an extreme manifestation of bipolar disorder. The primary symptoms of manic delirium are confusion, agitation, altered levels of consciousness, and perceptual disturbances. Our patient developed typical symptoms of manic delirium; however, this case diff

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LaHue, Sara, Joy Youn, Matias Fuentealba, et al. "ACCELERATED BIOLOGICAL AGE IS ASSOCIATED WITH DELIRIUM AND PLASMA NEUROFILAMENT LIGHT IN GERIATRIC HIP FRACTURE." Innovation in Aging 7, Supplement_1 (2023): 119. http://dx.doi.org/10.1093/geroni/igad104.0387.

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Abstract Background Biological age may be distinct from chronological age. Epigenetic clocks (e.g., PhenoAge) estimate biological age by quantifying changes in DNA methylation (DNAm). Biological age is “accelerated” (AgeAccel) when epigenetic&gt;chronological age. AgeAccel predicts age-related diseases but its association with delirium or neuronal injury markers (e.g., neurofilament light “NfL”) is unknown. Methods Adults age 65+ hospitalized for acute hip fracture underwent daily delirium screening with the Confusion Assessment Method Long Form. DNAm status of 850,000 CpG sites was measur

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Banerdt, Justin K., Kondwelani Mateyo, Li Wang, et al. "Delirium as a predictor of mortality and disability among hospitalized patients in Zambia." PLOS ONE 16, no. 2 (2021): e0246330. http://dx.doi.org/10.1371/journal.pone.0246330.

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Objective To study the epidemiology and outcomes of delirium among hospitalized patients in Zambia. Methods We conducted a prospective cohort study at the University Teaching Hospital in Lusaka, Zambia, from October 2017 to April 2018. The primary exposure was delirium duration over the initial 3 days of hospitalization, assessed daily using the Brief Confusion Assessment Method. The primary outcome was 6-month mortality. Secondary outcomes included 6-month disability, evaluated using the World Health Organization Disability Assessment Schedule 2.0. Findings 711 adults were included (median ag

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Linkaitė, Gabrielė, Mantas Riauka, Ignė Bunevičiūtė, and Saulius Vosylius. "Evaluation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for the patients in the intensive care unit." Acta medica Lituanica 25, no. 1 (2018): 14–22. http://dx.doi.org/10.6001/actamedica.v25i1.3699.

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Introduction. Delirium not only compromises patient care, but is also associated with poorer outcomes: increased duration of mechanical ventilation, higher mortality, and greater long-term cognitive dysfunction. The PRE-DELIRIC model is a tool used to calculate the risk of the development of delirium. The classification of the patients into groups by risk allows efficient initiation of preventive measures. The goal of this study was to validate the PRE-DELIRIC model using the CAM-ICU (The Confusion Assessment Method for the Intensive Care Unit) method for the diagnosis of delirium. Materials a

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Bode, Leonie, Florian Isler, Simon Fuchs, et al. "The utility of nursing instruments for daily screening for delirium: Delirium causes substantial functional impairment." Palliative and Supportive Care 18, no. 3 (2019): 293–300. http://dx.doi.org/10.1017/s1478951519001019.

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AbstractObjectiveNursing assessments have been recommended for the daily screening for delirium; however, the utility of individual items have not yet been tested. In a first step in establishing the potential of the electronic Patient Assessment-Acute Care (ePA-AC) as such, the impact of delirium on the functional domains was assessed.MethodIn this prospective observational cohort study, 277 patients were assessed and 118 patients were delirious. The impact of delirium on functional domains of the ePA-AC related to self-initiated activity, nutrition, and elimination was determined with simple

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O’Neill, Liam, and Neale R. Chumbler. "Examining the risk of delirium in patients hospitalized with COVID-19: Insights from the homeless population." PLOS ONE 20, no. 1 (2025): e0313242. https://doi.org/10.1371/journal.pone.0313242.

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For patients hospitalized with COVID-19, delirium is a serious and under-recognized complication, and people experiencing homelessness (PEH) may be at greater risk. This retrospective cohort study compared delirium-associated risk factors and clinical outcomes between PEH and non-PEH. This study used patient records from 154 hospitals discharged from 2020–2021 from the Texas Inpatient Public Use Data file. Study subjects (n = 878) were patients, aged 18–69 years, who were hospitalized with COVID-19 and were identified as homeless. The baseline group included (n = 176,518) patients with COVID-1

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Grover, Sandeep, Sanjana Kathiravan, and Devakshi Dua. "Delirium Research in India: A Systematic Review." Journal of Neurosciences in Rural Practice 12, no. 02 (2021): 236–66. http://dx.doi.org/10.1055/s-0041-1725211.

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AbstractDelirium is the most common psychiatric diagnoses encountered in patients with various medical-surgical illnesses, in all the treatment set-ups, with relatively higher incidence and prevalence in the intensive care units. As delirium is encountered in multiple specialties, it is important to understand the research on this diagnosis. This study aims to assess the research output involving patients of delirium from India. A comprehensive search was undertaken using Medline (PubMed) and other databases. Search words included were “delirium,” “delirious,” “delirium tremens” AND “India.” N

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Williams, John, Karen Finn, Vincent Melvin, David Meagher, Geraldine McCarthy, and Dimitrios Adamis. "The Association of Serum Levels of Brain-Derived Neurotrophic Factor with the Occurrence of and Recovery from Delirium in Older Medical Inpatients." BioMed Research International 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/5271395.

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Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery from delirium. Participants were assessed twice weekly using MoCA, DRS-R98, and APACHE II scales. BDNF levels were estimated using an ELISA method. Delirium was defined with DRS-R98 (score > 16) and recovery from delirium as ≥2 consecutive assessments without delirium prior to discharge. We identified no difference in BDNF levels between those with and without delirium. Exclu

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Rudolph, James L., Viken L. Babikian, Patrick Treanor, et al. "Microemboli are not associated with delirium after coronary artery bypass graft surgery." Perfusion 24, no. 6 (2009): 409–15. http://dx.doi.org/10.1177/0267659109358207.

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Delirium is an acute change in cognition which occurs frequently after coronary artery bypass graft (CABG) surgery. Cerebral microemboli, from plaque, air, or thrombus, have been hypothesized to contribute to delirium and cognitive decline after CABG. The purpose of this study was to determine if there was an association between cerebral microemboli and delirium after cardiac surgery. Non-delirious patients (n=68) were prospectively enrolled and underwent intraoperative monitoring of the middle cerebral arteries with transcranial Doppler (TCD). TCD signals were saved and analyzed postoperative

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Ragheb, Jacqueline, Amy McKinney, Mackenzie Zierau, et al. "Delirium and neuropsychological outcomes in critically Ill patients with COVID-19: a cohort study." BMJ Open 11, no. 9 (2021): e050045. http://dx.doi.org/10.1136/bmjopen-2021-050045.

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ObjectiveTo characterise the clinical course of delirium for patients with COVID-19 in the intensive care unit, including postdischarge neuropsychological outcomes.DesignRetrospective chart review and prospective survey study.SettingIntensive care units, large academic tertiary-care centre (USA).ParticipantsPatients (n=148) with COVID-19 admitted to an intensive care unit at Michigan Medicine between 1 March 2020 and 31 May 2020 were eligible for inclusion.Primary and secondary outcome measuresDelirium was the primary outcome, assessed via validated chart review method. Secondary outcomes incl

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Denke, Claudia, Felix Balzer, Mario Menk, et al. "Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder." Journal of International Medical Research 46, no. 6 (2018): 2265–83. http://dx.doi.org/10.1177/0300060518762040.

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Objective Delirium in critically ill patients is considered a risk factor for various long-term consequences. We evaluated delirium and associated long-term outcomes in patients with acute respiratory distress syndrome with non-H1N1 and H1N1- associated severe community-acquired pneumonia (sCAP) who had been recommended to take antiviral drugs associated with delirious symptoms as adverse effects. Methods Of 64 patients, 42 survivors (H1N1, 15; non-H1N1, 27) were analyzed regarding the relationship between medication and the duration of delirium in the intensive care unit. During follow-up (n

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Cho, Eun Ju, and Myoung Soo Kim. "Comparison of the Validity of the PRE-DELIRIC model and the E-PRE-DELIRIC model for Predicting Delirium in patients after Cardiac Surgery." Journal of Korean Academy of Fundamentals of Nursing 31, no. 3 (2024): 275–85. http://dx.doi.org/10.7739/jkafn.2024.31.3.275.

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Purpose: The purpose of this study was to analyze the validity of the PRE-DELIRIC model and E-PRE-DELIRIC model.Methods: Patients who underwent cardiac surgery at a tertiary hospital between January 2019 and December 2022 were included. The presence or absence of delirium was determined based on risk groups, and the sensitivity, specificity, positive predictive power, and negative predictive power were verified using the Youden index. Receiver operating characteristic curves were derived for the PRE-DELIRIC model and E-PRE-DELIRIC model, the area under the curve was calculated, and the 95% con

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Brown, Charles H., Julia Probert, Ryan Healy, et al. "Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery." Anesthesiology 129, no. 3 (2018): 406–16. http://dx.doi.org/10.1097/aln.0000000000002253.

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Abstract What We Already Know about This Topic What This Article Tells Us That Is New Background Delirium is common after cardiac surgery and has been associated with morbidity, mortality, and cognitive decline. However, there are conflicting reports on the magnitude, trajectory, and domains of cognitive change that might be affected. The authors hypothesized that patients with delirium would experience greater cognitive decline at 1 month and 1 yr after cardiac surgery compared to those without delirium. Methods Patients who underwent coronary artery bypass and/or valve surgery with cardiopul

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Rahkonen, Terhi, Helena Mäkelä, Satu Paanila, Pirjo Halonen, Juhani Sivenius, and Raimo Sulkava. "Delirium in Elderly People Without Severe Predisposing Disorders: Etiology and 1-Year Prognosis After Discharge." International Psychogeriatrics 12, no. 4 (2000): 473–81. http://dx.doi.org/10.1017/s1041610200006591.

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Background: The etiologic factors of delirium have been frequently studied in hospitalized elderly patients who usually have an underlying disorder, i.e., hip fracture or dementia predisposing to delirium. The etiologic factors of delirium and prognosis in healthy elderly remain unstudied. The aim of our study was to detect the primary and additional etiologic factors contributing to delirium among community-dwelling healthy elderly people without predisposing disorders to delirium and to evaluate 1-year prognosis after discharge to home. Method: The study subjects consisted of 51 community-dw

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Wood, MD, D. Maslove, J. Muscedere, and JG Boyd. "E.04 Coma and delirium are associated with low levels of brain tissue oxygen in critically ill patients." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 43, S2 (2016): S17. http://dx.doi.org/10.1017/cjn.2016.88.

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Background: The cause of ICU delirium is unknown. We used near infrared spectroscopy (NIRS) to measure brain tissue oxygenation (BtO2) in critically ill patients, to test the hypothesis that poor cerebral oxygen delivery contributes to ICU delirium. Methods: Adult patients were enrolled if they required mechanical ventilation for >24 hours, and/or vasoactive agents. Patients were excluded if they had previous cognitive dysfunction, brain injury on admission, or a life expectancy <24 hours. BtO2 was measured for the first 24 hours of ICU admission. The confusion assessment method-ICU (CAM

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Stevens, Lee E., Gregory M. de Moore, and Judy M. Simpson. "Delirium in Hospital: Does it Increase Length of Stay?" Australian & New Zealand Journal of Psychiatry 32, no. 6 (1998): 805–8. http://dx.doi.org/10.3109/00048679809073869.

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Objective: To determine the effect of delirium, as a comorbid diagnosis in hospitalised patients, on patient length of stay (LOS). Method: Prospective study comparing LOS of delirious patients with controls matched by age, gender, principal diagnosis and date of admission. Medical and surgical inpatients of Westmead Hospital with delirium were identified from a Consultation Liaison (CL) psychiatry database and were matched with controls from the hospital medical records. Results: Delirious patient LOS was found to be significantly longer (2.2-fold; 95% confidence interval 1.5-3.3) than matched

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Reznik, Michael E., Scott Moody, Kayleigh Murray, et al. "The impact of delirium on withdrawal of life-sustaining treatment after intracerebral hemorrhage." Neurology 95, no. 20 (2020): e2727-e2735. http://dx.doi.org/10.1212/wnl.0000000000010738.

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ObjectiveTo determine the impact of delirium on withdrawal of life-sustaining treatment (WLST) after intracerebral hemorrhage (ICH) in the context of established predictors of poor outcome, using data from an institutional ICH registry.MethodsWe performed a single-center cohort study on consecutive patients with ICH admitted over 12 months. ICH features were prospectively adjudicated, and WLST and corresponding hospital day were recorded retrospectively. Patients were categorized using DSM-5 criteria as never delirious, ever delirious (either on admission or later during hospitalization), or p

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Aitken, Sarah Joy, Fiona M. Blyth, and Vasi Naganathan. "Incidence, prognostic factors and impact of postoperative delirium after major vascular surgery: A meta-analysis and systematic review." Vascular Medicine 22, no. 5 (2017): 387–97. http://dx.doi.org/10.1177/1358863x17721639.

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Although postoperative delirium is a common complication and increases patient care needs, little is known about the predictors and outcomes of delirium in patients having vascular surgery. This review aimed to determine the incidence, prognostic factors and impact of postoperative delirium in vascular surgical patients. MEDLINE and EMBASE were systematically searched for articles published between January 2000 and January 2016 on delirium after vascular surgery. The primary outcome was the incidence of delirium. Secondary outcomes were contributing prognostic factors and impact of delirium. S

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Kotfis, Katarzyna, Wojciech Witkiewicz, Aleksandra Szylińska, et al. "Delirium Severely Worsens Outcome in Patients with COVID-19—A Retrospective Cohort Study from Temporary Critical Care Hospitals." Journal of Clinical Medicine 10, no. 13 (2021): 2974. http://dx.doi.org/10.3390/jcm10132974.

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Delirium is a sign of deterioration of homeostasis and worse prognosis. The aim of this study was to investigate the frequency, risk factors and prognosis of delirium in patients with COVID-19 in a temporary acute setting hospital. A retrospective cohort analysis of data collected between October 2020 and February 2021 from two temporary acute care hospitals was performed. All consecutive hospitalized patients ≥18 years old with COVID-19 were included. An assessment of consciousness was carried out at least two times a day, including neurological examination. Delirium was identified through re

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Cyr, Monica, S. Casey Laizure, and Carl M. daCunha. "Methazolamide‐Induced Delirium." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 17, no. 2 (1997): 387–89. http://dx.doi.org/10.1002/j.1875-9114.1997.tb03726.x.

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A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. This is the first case reported of delirium associated with methazolamide not accompanied by a metabolic imbalance.

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Landreville, Philippe, Philippe Voyer, and Pierre-Hugues Carmichael. "Relationship between delirium and behavioral symptoms of dementia." International Psychogeriatrics 25, no. 4 (2012): 635–43. http://dx.doi.org/10.1017/s1041610212002232.

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ABSTRACTBackground: Persons with dementia frequently present behavioral and psychological symptoms as well as delirium. However, the association between these has received little attention from researchers and current knowledge in this area is limited. The purpose of this study was to examine the relation between delirium and behavioral symptoms of dementia (BSD).Methods: Participants were 155 persons with a diagnosis of dementia, 109 (70.3%) of whom were found delirious according to the Confusion Assessment Method. BSD were assessed using the Nursing Home Behavior Problem Scale.Results: Parti

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Kajawo, S., D. Flynn, and M. Buckley. "221 PREVALENCE AND DOCUMENTATION OF DELIRIUM IN A UNIVERSITY HOSPITAL." Age and Ageing 50, Supplement_3 (2021): ii9—ii41. http://dx.doi.org/10.1093/ageing/afab219.221.

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Abstract Background Delirium can complicate approximately 10% of all medical admissions and prevalence increases in those with cognitive impairment, increasing age and medical complexity. Delirium is associated with increased morbidity and mortality as well as increased length of stay. Prompt recognition and treatment is essential. The National Delirium Care Bundle suggests assessment and recognition at the earliest opportunity and documentation of delirium if patients screen positive. Methods We carried out an audit among patients admitted in all medical wards to identify delirium and assess

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