Letteratura scientifica selezionata sul tema "DMCI"

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Articoli di riviste sul tema "DMCI":

1

Eppig, Joel, Denene Wambach, Christine Nieves, Catherine C. Price, Melissa Lamar, Lisa Delano-Wood, Tania Giovannetti et al. "Dysexecutive Functioning in Mild Cognitive Impairment: Derailment in Temporal Gradients". Journal of the International Neuropsychological Society 18, n. 1 (7 ottobre 2011): 20–28. http://dx.doi.org/10.1017/s1355617711001238.

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AbstractLibon et al. (2010) provided evidence for three statistically determined clusters of patients with mild cognitive impairment (MCI): amnesic (aMCI), dysexecutive (dMCI), and mixed (mxMCI). The current study further examined dysexecutive impairment in MCI using the framework of Fuster's (1997) derailed temporal gradients, that is, declining performance on executive tests over time or test epoch. Temporal gradients were operationally defined by calculating the slope of aggregate letter fluency output across 15-s epochs and accuracy indices for initial, middle, and latter triads from the Wechsler Memory Scale-Mental Control subtest (Boston Revision). For letter fluency, slope was steeper for dMCI compared to aMCI and NC groups. Between-group Mental Control analyses for triad 1 revealed worse dMCI performance than NC participants. On triad 2, dMCI scored lower than aMCI and NCs; on triad 3, mxMCI performed worse versus NCs. Within-group Mental Control analyses yielded equal performance across all triads for aMCI and NC participants. mxMCI scored lower on triad 1 compared to triads 2 and 3. dMCI participants also performed worse on triad 1 compared to triads 2 and 3, but scored higher on triad 3 versus triad 2. These data suggest impaired temporal gradients may provide a useful heuristic for understanding dysexecutive impairment in MCI. (JINS, 2012, 18, 20–28)
2

Miller, Victoria A., Richard F. Ittenbach, Diana Harris, William W. Reynolds, Tom L. Beauchamp, Mary Frances Luce e Robert M. Nelson. "The Decision Making Control Instrument to Assess Voluntary Consent". Medical Decision Making 31, n. 5 (14 marzo 2011): 730–41. http://dx.doi.org/10.1177/0272989x11398666.

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Background. The decision to participate in a research intervention or to undergo medical treatment should be both informed and voluntary. Objective. The aim of the present study was to develop an instrument to measure the perceived voluntariness of parents making decisions for their seriously ill children. Methods. A total of 219 parents completed questionnaires within 10 days of making such a decision at a large, urban tertiary care hospital for children. Parents were presented with an experimental form of the Decision Making Control Instrument (DMCI), a measure of the perception of voluntariness. Data obtained from the 28-item form were analyzed using a combination of both exploratory and confirmatory factor analytic techniques. Results. The 28 items were reduced to 9 items representing 3 oblique dimensions: Self-Control, Absence of Control, and Others’ Control. The hypothesis that the 3-factor covariance structure of our model was consistent with that of the data was supported. Internal consistency for the scale as a whole was high (0.83); internal consistency for the subscales ranged from 0.68 to 0.87. DMCI scores were associated with measures of affect, trust, and decision self-efficacy, supporting the construct validity of the new instrument. Conclusion. The DMCI is an important new tool that can be used to inform our understanding of the voluntariness of treatment and research decisions in medical settings.
3

Galbusera, Luca, Paolo Trucco e Georgios Giannopoulos. "Modeling interdependencies in multi-sectoral critical infrastructure systems: Evolving the DMCI approach". Reliability Engineering & System Safety 203 (novembre 2020): 107072. http://dx.doi.org/10.1016/j.ress.2020.107072.

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Park, Mi-Jeong, Doo-Nam Oh, Young-Lim Ham, Seung-Joo Lim e Young-Mi Lim. "Reliability and Validity of the Decision-Making-Competency Inventory (DMCI) in Korean Adolescents". Journal of Korean Academy of Child Health Nursing 18, n. 2 (2012): 53. http://dx.doi.org/10.4094/jkachn.2012.18.2.53.

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Putman, Sophie, Julien Dartus, Henri Migaud, Gilles Pasquier, Julien Girard, Cristian Preda e Alain Duhamel. "La différence minimale cliniquement importante (DMCI) peut-elle être identifiée sur un échantillon français d’arthroplasties totales de la hanche ? Méthode de mesure de la DMCI utilisant comme ancre un item du questionnaire". Revue de Chirurgie Orthopédique et Traumatologique 107, n. 3 (maggio 2021): 285–93. http://dx.doi.org/10.1016/j.rcot.2021.01.018.

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Wainberg, Zev A., Jennifer Robinson Diamond, Giuseppe Curigliano, Sanjeev Deva, Johanna C. Bendell, Sae-Won Han, Aparna Kalyan et al. "First-line durvalumab + monalizumab, mFOLFOX6, and bevacizumab or cetuximab for metastatic microsatellite-stable colorectal cancer (MSS-CRC)." Journal of Clinical Oncology 38, n. 4_suppl (1 febbraio 2020): 128. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.128.

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128 Background: Targeting multiple immune checkpoint pathways and combining checkpoint inhibition with chemotherapy may enhance response in MSS-CRC. In a Phase 1/2, multicenter, open-label study, the anti-PD-L1 antibody durvalumab (D) was added to monalizumab (M; an anti-NKG2A antibody). In dose-exploration cohorts, D+M was added to chemotherapy and a biologic agent (bevacizumab [DMCB] or cetuximab [DMCC]) for first-line treatment of advanced/metastatic MSS-CRC. Initial data showed DMCB was well tolerated and clinically active. Here we report updated efficacy and safety of DMCB and initial safety of DMCC. Methods: Eligible patients (pts) had MSS-CRC ( RAS/BRAF wt with a left-sided colon primary tumor in the DMCC cohort) and ECOG PS 0–1. They received D 1500 mg Q4W, M 750 mg Q2W, mFOLFOX6 Q2W and bevacizumab 5 mg/kg Q2W or cetuximab 250/400 mg/m2 QW (up to 500 mg/m2 Q2W) for up to 3 yr. The primary endpoint was safety and tolerability; secondary endpoints included antitumor activity. Results: As of Aug 26, 2019, 18 pts received DMCB and 17 pts received DMCC. Treatment-emergent adverse events (AEs) occurred in 100.0% of the DMCB cohort (most commonly fatigue, nausea and peripheral neuropathy) and 94.1% of the DMCC cohort (most commonly peripheral neuropathy, rash and dermatitis acneiform). The AEs were grade 3/4 in 77.8% of pts receiving DMCB and 70.6% of pts receiving DMCC, and were serious in 38.9% and 47.1%, respectively. Response was evaluable in 17 pts receiving DMCB; objective response rate was 41.2% (all PRs; Table). Responses occurred early and the median duration of response has not yet been reached. Conclusions: In advanced/metastatic MSS-CRC, first-line DMCB and DMCC had a manageable safety profile and DMCB showed promising preliminary activity. Clinical trial information: NCT02671435. [Table: see text]
7

El-Hendawy, Salah, Nasser Al-Suhaibani, Yaser Dewir, Salah Elsayed, Majed Alotaibi, Wael Hassan, Yahya Refay e Muhammad Tahir. "Ability of Modified Spectral Reflectance Indices for Estimating Growth and Photosynthetic Efficiency of Wheat under Saline Field Conditions". Agronomy 9, n. 1 (16 gennaio 2019): 35. http://dx.doi.org/10.3390/agronomy9010035.

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Hyperspectral sensing offers a quick and non-destructive alternative for assessing phenotypic parameters of plant physiological status and salt stress tolerance. This study compares the performance of published and modified spectral reflectance indices (SRIs) for estimating and predicting the growth and photosynthetic efficiency of two wheat cultivars exposed to three salinity levels (control, 6.0, and 12.0 dS m−1). Results show that individual SRIs based on visible- and near-infrared (VIS/VIS, NIR/VIS, and NIR/NIR) estimate and predict measured parameters considerably more efficiently than those based on shortwave-infrared (SWIR/VIS and SWIR/NIR), with the exception of some modified indices (the water balance index (WABI-1(1550, 482), WABI-2(1640, 482), and WABI-3(1650, 531)), normalized difference moisture index (NDMI(1660, 1742)), and dry matter content index (DMCI(1550, 2305)), which show moderate to strong relationships with measured parameters. Overall results indicate that modified SRIs can serve as rapid and non-destructive high-throughput alternative approaches for tracking growth and photosynthetic efficiency of wheat under salt stress field conditions.
8

Kerr, David, e Kent Koprowicz. "Special considerations of DMCs for oncology studies." Journal of Clinical Oncology 35, n. 15_suppl (20 maggio 2017): e20071-e20071. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e20071.

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e20071 Background: Data Monitoring Committees (DMCs) are an important component of the clinical trial process. They are charged with reviewing interim data and making recommendations to protect the safety of trial participants and ensure the scientific integrity of the study. Oncologists may be involved with the DMC process in a number of ways – as a DMC member, as an investigator, as a sponsor, or in a regulatory role. This presentation will discuss novel aspects of the DMC review process that are particularly relevant for oncology trials. Methods: The authors are leaders of a Contract Research Organization (CRO) that specializes in providing independent DMC services for government and industry sponsored trials. They have worked with hundreds of unique DMCs and facilitated approximately 1,000 DMC meetings. The proposed methodologies for maximizing the efficiency and thoroughness of DMC reviews are based on extensive experience and well-established principles. Results: Topics that will be covered include: Discrepant trends in PFS vs. OS PFS results that are inconsistent between local and central assessment, or are not yet centrally assessed Co-primary endpoints – OS, PFS, ORR, CR Multiple populations of interest – ITT and a biomarker subgroup Interim analyses – overwhelming efficacy and statistical futility Program-wide DMCs – interpreting trends across multiple studies and logistical details Safety assessment in a study with thousands of AEs – novel graphics and tables Laboratory values and vital signs – novel graphics and tables Multiple comparisons and/or multiple p-values Non-standard tables, listings, figures that are particularly useful for DMC review Open-label studies – immediate withdrawals for those randomized to control arm and other potential biases Single-arm studies – how to interpret safety with no control arm Novel therapies – immune-oncology, CAR-T, small sample sizes CIOMS reports or patient narratives Conclusions: DMCs will perform a more thorough and efficient review of accumulating data upon adapting the guidance provided. A more thorough review will enhance the protection of the trial participants while a more efficient review will allow DMCs to focus their efforts appropriately.
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Diener, Andrew C., e Gerald R. Fink. "DLH1 is a Functional Candida albicans Homologue of the Meiosis-Specific Gene DMC1". Genetics 143, n. 2 (1 giugno 1996): 769–76. http://dx.doi.org/10.1093/genetics/143.2.769.

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Abstract DMC1/LIM15 homologue 1 (DLH1), a gene related to meiosis-specific genes, has been isolated from Candida albicans, a fungus thought not to undergo meiosis. The deduced protein sequence of DLH1 contains 74% amino acid identity with Dmclp from Saccharomyces cermisiae and 63% with Liml5p from the plant Lilium long)lmm, meiosisspecific homologues of Escherichia coli RecA. Candida DLH1 complements a dmcl/dmcl null mutant in S. cermisiae: High copy expression of DLH1 restores both sporulation and meiotic recombination to a Saccharomyces dmclΔ/dmclΔ strain. Unlike the DMCl gene, which is transcribed only in meiotic cells, the heterologous Candida DLH1 gene is transcribed in both vegetative and meiotic cells of S. cermisiae. Transcription of DLH1 is not detected or induced in C. albicans under conditions that induce DMC1 and meiosis in S. cermisiae. The presence of an intact homologue of a meiosis-specific gene in C. albicans raises the possibility that this organism has a cryptic meiotic pathway.
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Huang, Jinxin, Xingguang Zhang, Juan Li, Liya Tang, Xiumin Jiao e Xiaofeng Lv. "Impact of Glucose Fluctuation on Acute Cerebral Infarction in Type 2 Diabetes". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 41, n. 4 (luglio 2014): 486–92. http://dx.doi.org/10.1017/s0317167100018539.

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Objective:This study aimed to describe the frequency and temporal profile of acute cerebral infarction (ACI) using a continuous glucose monitoring system (CGMS) in patients with and without type 2 diabetes mellitus (T2DM) and explore the impact of blood glucose fluctuations on the short-term prognosis of ACI.Methods:The subjects were divided into four groups: T2DM with acute cerebral infarction (DMCI, Group A, n=56); T2DM without acute cerebral infarction (DM-NCI, Group B, n=36); Acute cerebral infarction patients without T2DM (NDM-CI, Group C, n=54); Healthy control group (NG, Group D, n=36). The National Institutes of Health Stoke Scale (NIHSS) and modified Rankin scale (mRs) were collected in Group A and C. All subjects were monitored for 72 hours using the CGMS. Indices such as fasting blood glucose (FBG) and mean amplitude of glycemic excursions (MAGE) were calculated. Glycemic excursions were compared between Group A, B, C and Group D, respectively. Multiple linear regression analysis and logistic analysis was applied.Results:MAGE is related to NIHSS, homocysteine (HCY), HOMA-IR, FBG, CRP and IMT, while NIHSS is related to CRP, HCY, HOMA-IR, IMT. The factors impacting the short-term prognosis of ACI were NIHSS, HBA1C and MAGE.Conclusion:Larger glucose fluctuations are associated with more stroke risk factors and are associated with a poorer short-term prognosis. More attention should be paid to glucose fluctuations in patients with ACI and a history of T2DM.

Tesi sul tema "DMCI":

1

Ilustrisimo, Tom. "Characterization of the DMCI and Rad51 homologues and the process of meiosis in trichomonas vaginalis". Scholarly Commons, 2013. https://scholarlycommons.pacific.edu/uop_etds/861.

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Trichomonas vaginal is is the sexually transmitted agent of trichomoniasis. Although the organism is believed to only reproduce via binary fission, genes specific to 5 Meiosis and Homologous Recombination have been identified in its genome. It is unclear whether the organism has the ability to undergo sexual reproduction or if it has lost that ability over time. Aside from meiosis, these genes could be expressed for use in antigenic variation and in the creation or transfer of resistance genes to other cells. In this study, we induced the expression ofDMCl and Rad51 homologues-key players in Homologous Recombination-using a system of tetracycline induction. We localized DMCl to both the cytoplasm and the nucleus, while Rad51 is localized to the nucleus. We performed a DNA strand exchange that suggests DMCl may be capable of DNA strand exchange. We also developed a system to determine whether haploid cells of Trichomonas vaginal is are capable of cytoplasmic fusion through the use of fluorescent proteins. Specifically, this study focuses on a line of Green Fluorescent Protein-expressing cells.
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Ilustrisimo, Tom. "Characterization of the DMCI and Rad51 homologues and the process of meiosis in trichomonas vaginalis : a thesis". Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/861.

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Trichomonas vaginal is is the sexually transmitted agent of trichomoniasis. Although the organism is believed to only reproduce via binary fission, genes specific to 5 Meiosis and Homologous Recombination have been identified in its genome. It is unclear whether the organism has the ability to undergo sexual reproduction or if it has lost that ability over time. Aside from meiosis, these genes could be expressed for use in antigenic variation and in the creation or transfer of resistance genes to other cells. In this study, we induced the expression ofDMCl and Rad51 homologues-key players in Homologous Recombination-using a system of tetracycline induction. We localized DMCl to both the cytoplasm and the nucleus, while Rad51 is localized to the nucleus. We performed a DNA strand exchange that suggests DMCl may be capable of DNA strand exchange. We also developed a system to determine whether haploid cells of Trichomonas vaginal is are capable of cytoplasmic fusion through the use of fluorescent proteins. Specifically, this study focuses on a line of Green Fluorescent Protein-expressing cells.
3

Franca, Aline Aguiar da. "Controle preditivo DMC". reponame:Repositório Institucional da UFSC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/100763.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2012.
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Este trabalho tem por objetivo apresentar um estudo relacionado ao controlador preditivo DMC (Dynamic Matrix Control) em suas formas linear e não-linear. O DMC é um controlador preditivo baseado em modelo (MPC - Model Predictive Control) que emprega os elementos da resposta ao degrau para gerar as predições da saída do processo. A ampla utilização de sua forma linear ocorre devido à simplicidade dos modelos lineares empregados para representar o comportamento do processo, mas estes se tornam inadequados quando é necessária uma representação mais realística de um processo complexo. Os processos reais geralmente apresentam características não-lineares que devem ser representadas por modelos não-lineares. O modelo de Hammerstein, que é formado por uma parcela estática não-linear e uma parcela dinâmica linear, é o selecionado para representar os processos não-lineares desta dissertação. Este modelo apresenta propriedades que simplificam o projeto do controlador DMC não-linear e possibilitam a determinação de uma solução analítica para o problema de minimização da função custo (caso sem restrições). Primeiramente, é realizado um estudo sobre o efeito da sintonia dos parâmetros do controlador DMC e sobre métodos para realizar estas sintonias de forma eficiente. Além disto, são apresentadas novas estruturas para o controlador DMC (DMC-RST e DMC-IMC), considerando também os casos com restrição de controle. Através de modelos de Hammerstein, é comprovada a ineficiência do controlador DMC linear em meio a sistemas não-lineares. E como solução para este problema são introduzidos o controle linearizante e o controle DMC não-linear baseado em modelo de Hammerstein. Também é exposto neste trabalho métodos de resolução do problema da multiplicidade de soluções de controle para o sinal de controle não-linear.

Abstract : This work aims to present a study related to the predictive controller DMC (Dynamic Matrix Control) in its linear and nonlinear forms. The DMC is a model predictive controller (MPC) that employs elements of the step response to generate predictions of the process output. The wide use of its linear form is due to the simplicity of linear models used to represent the process behavior, but these become inadequate when it is necessary a more realistic representation of a complex process. Real processes generally exhibit nonlinear characteristics that must be represented by nonlinear models. The Hammerstein model, which is composed by a nonlinear static portion and a linear dynamic portion, is selected to represent the nonlinear processes of this dissertation. This model has properties that simplify the nonlinear DMC design and enable the determination of an analytical solution for the problem of minimizing the cost function (unrestricted case). First of all, a study about the effect of tuning the DMC parameters and the methods for performing these tuning efficiently is accomplished. In addition, new structures are presented to the DMC (DMC-RST and DMC-IMC), also considering the cases with restricted control. Through Hammerstein models is shown the inefficiency of the linear DMC among nonlinear systems. As a solution to this problem is introduced the linearizing control and the nonlinear DMC based on a Hammerstein model. It is also exposed in this work methods of solving the problem of multiplicity of control solutions for the nonlinear control signal.
4

Fai, Yu Chuen. "Utvärdering av övervakningsapplikationen DMCG i SL Access". Thesis, Högskolan i Borås, Institutionen Ingenjörshögskolan, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20266.

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Syftet med detta examensarbete ”Utvärdering av övervakningsapplikation DMCG i SL Access” är att vara ett underlag för en ny version av programmet. En kartläggning av applikationens uppbyggnad, funktionalitet och gränssnitt gjordes. Synpunkter och förslag från operatörer som använder programmet samlades in och sammanfattas i rapporten.Den nuvarande versionen av programmet har ett antal brister i de tre områdena. Detta presenteras i examensarbetet så att SL kan använda detta för att skriva ett ändringsförslag till leverantören ERG. Flödet för larm från fo-enheterna visas i en schematisk bild. Ett förslag på förändrad uppbyggnad av larmfunktionalitet, övriga funktioner samt gränssnittet presenteras.DMCG är ett verktyg som kommer att användas av personal som övervakar fo-enheterna, Bärbar biljettmaskin, Biljettmaskin (TP5000, bussvarianten och ombudsvarianten), Kortläsaren (CP5000), SL Access biljettautomat samt automatspärrar. Totalt är det över 2000 enheter som skall övervakas. SL Access är tänkt att leva i minst 15 år och mängden enheter medför att existerande funktionalitet behövs ses över för att verktyget blir så optimerat så möjligt.
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Grisot, Giorgia. "Validation of dMRI techniques for mapping brain pathways". Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122194.

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This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Thesis: Ph. D., Harvard-MIT Program in Health Sciences and Technology, 2019
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 201-222).
Diffusion magnetic resonance imaging (dMRI) tractography is the only non-invasive tool for studying the connectional architecture of the brain in vivo. By measuring the diffusion of water molecules dMRI provides unique information about white matter pathways and their integrity, making it an invaluable neuroimaging tool that has improved our understanding of the human brain and how it is affected by disease. A major roadblock to its acceptance into clinical practice has been the difficulty in assessing its anatomical accuracy and reliability. In fact, obtaining a map of brain pathways is a multi-step process with numerous variables, assumptions and approximations that can influence the veracity of the generated pathways. Validation is, thus, necessary and yet challenging because there is no gold standard which dMRI can be compared to, since the configuration of human brain connections is largely unknown. Which aspects of tractography processing have the greatest effect on its performance? How do mapping methods compare? Which one is the most anatomically accurate? We tackle these questions with a multi-modal approach that capitalizes on the complementary strengths of available validation strategies to probe dMRI performance on different scales and across a wide range of acquisition and analysis parameters. The outcome is a multi-layered validation of dMRI tractography that 1) quantifies dMRI tractography accuracy both on the level of brain connections and tissue microstructure; 2) highlights the strengths and weaknesses of different modeling and tractography approaches, offering guidance on the issues that need to be resolved to achieve a more accurate mapping of the human brain.
by Giorgia Grisot.
Ph. D.
Ph.D. Harvard-MIT Program in Health Sciences and Technology
6

Monasterios, Morales Daniel Santos. "Sintonia de controladores DMC utilizando algoritmos geneticos". [s.n.], 1995. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261671.

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Orientador: Wagner Caradori do Amaral
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica
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Resumo: Este trabalho descreve a aplicação de um algoritmo genético para a sintonia de controladores DMC (Dynamic Matrix Control). Sintonizar um controlador DMC consiste no ajuste de certos parâmetros (horizontes de previsão e controle, ponderações nas ações de controle e nos erros das saídas em relação às respectivas referências). Este ajuste é realizado normalmente por um especialista, a partir de sua experiência anterior na utilização do algoritmo. Em vista disto, é proposta neste trabalho, uma metodologia que possa dar ao usuário bons valores para os parâmetros do controlador DMC. Esta metodologia de sintonia utiliza um algoritmo genético que seleciona um conjunto restrito de valores para os horizontes de previsão e controle do algoritmo DMC. O ajuste das ponderações é feito de forma iterativa, a partir da observação da resposta do sistema em malha fechada. Este algoritmo é completamente independente da natureza do processo a ser controlado pelo algoritmo DMC, sendo igualmente válido para a simulação de processos com modelos lineares e não lineares. A metodologia proposta foi utilizada na sintonia de dois processos: uma coluna de destilação de alta pureza e uma coluna fracionadora de óleo pesado. Os resultados obtidos permitiram avaliar o desempenho do algoritmo genético utilizado na sintonia dos controladores DMC
Abstract: This work describes the application of a genetic algorithm to the tuning of DMC (Dynamic Matrix ControQ controllers. Tuning a DMC controller consists of adjusting some parameters (prediction and controI horizons, weights for the control actions and for the errors between the outputs and corresponding reference signals). This adjustment is generally achieved by an expert, based on his past experience using the algorithm. In this work is proposed a methodology to give the user good values for the DMC controller parameters. This methodology uses a genetic algorithm to select a small set of values to the prediction and control horizons of the DMC algorithm. The weights' adjustment is interactive, based on the observation of the response for. the closed Ioop system. This algorithm is completely independent from the nature of the process to be controlled by the DMC algorithm, being equally valid for the simulation of processes with linear and nonlinear models. The proposed methodology was applied to the tuning of two processes: a high purity distillation column and a heavy oil fractionator column. The obtained results allowed an performance analysis of the genetic algorithm used to tune DMC controllers
Mestrado
Mestre em Engenharia Elétrica
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Dechechi, Eduardo Cesar. "Controle avançado preditivo adaptativo"DMC multivariavel adaptativo"". [s.n.], 1998. http://repositorio.unicamp.br/jspui/handle/REPOSIP/267233.

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Orientador: Rubens Maciel Filho
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica
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Resumo: O assunto principal deste trabalho é o desenvolvimento e a aplicação da técnica de controle avançado preditivo DMC (Dynamic Matrix Control) desde o controlador monovariável, DMC-SISO, ao controlador multivariável DMC-MIMO, e também do controlador multivariável adaptativo, DMC-MIMO adaptativo, denominado neste trabalho de D-AMPC. O controle multivariável desenvolvido neste trabalho foi testado, via simulação por computador, em um processo complexo encontrado em aplicações industriais de Engenharia Química, processo fermentativo industrial para produção de Etanol, operado sob condições severas de operação. O controle multivariável preditivo adaptativo, D-AMPC, foi testado no reator de hidrogenação de Fenol para Cic1ohexanol (RHODIA - Paulínia SP). Este teste foi feito em um breve intervalo de tempo, sendo o processo controlado em tempo real e sob condições normais de operação. O processo fermentativo considerado neste trabalho é um processo de dinâmica lenta e que apresenta fortes não linearidades, características de sistemas distribuídos, as quais juntamente com a presença de atraso nos instrumentos de medida da variável controlada (concentração de açúcares) dificultam, em muito, o projeto do controlador. O reator de hidrogenação de Fenol para Ciclohexanol, da Usina Química de Paulínia (RHODIA) é um reator trifásico, com a presença do catalisador sólido na mistura. Possui fenômenos complexos de transferência de calor e dinâmica rápida quando comparado com o processo fermentativo industrial. Além do mais é um processo distribuído que apresenta, entre outras dificuldades, a desativação do catalisador ...Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digital
Abstract: The main subject of this work is the application and development of the advanced predictive control strategy, DMC 'Dynamic Matrix Control', from the monovariable approach (DMC-SISO) to the multivariable (DMC-MIMO) as well as the multivariable with adaptive capabilities, described in this work as D-AMPC. The multivariable controller developed in this work was tested by computer simulation in a complex industrial process application, to know, the industrial fermentation process to produce Ethanol under hard operational conditions. The multivariable predictive/adaptive controller was tested in the Phenol hydrogenation reactor to produce Cyclohexanol (RHODIA - Paulínia - SP - Brazil). This test could be made in a short time interval and the process was controlled in Real time under typical operational conditions. The fermentation process considered in this work is a process with low dynamic response, high non-linearities with typical characteristic of distributed systems. This behaviour and the large time delay in the measurement of the controlled variable (total sugar reductor) contribute to make the design of the controller very difficult. The Phenol hydrogenation reactor to obtain Cyclohexanol, a RHODIA unit in Paulínia SP (Brazil), is a three phase reactor with solid catalyst in the reaction mixture. This process has complex heat transfer mechanisms and fast dynamic behaviour when compared with the industrial fermentation process considered in this work ...Note: The complete abstract is available with the full electronic digital thesis
Doutorado
Desenvolvimento de Processos Químicos
Doutor em Engenharia Química
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Putman, Sophie. "Les scores hanche et genou en orthopédie : validation d’un score, définition d’une différence minimale cliniquement importante et méthodes de Mapping". Thesis, Lille 2, 2020. http://www.theses.fr/2020LIL2S014.

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Abstract (sommario):
Les scores d’autoévaluation (PROM = Patient Reported Outcome Measurement) font partie intégrante de l’évaluation moderne des patients. Ils permettent par exemple en orthopédie de définir un statut de base pour ces patients et ensuite après un traitement chirurgical ou médical, de définir une amélioration. Ces scores nécessitent des étapes de validation permettant leur utilisation (validité interne et externe, effet plancher et plafond, répétabilité, sensibilité au changement, traduction dans différentes langues,). Une fois ces étapes effectuées, la différence minimale cliniquement importante (DMCI ou MCID pour Minimal Clinical Important Difference) pour le patient peut être définie afin de fixer un niveau minimum d’amélioration. La DMCI, qui est une notion variable d’un pays à l’autre, peut être calculée par différentes méthodes notamment la méthode des ancres nécessitant une question supplémentaire afin de définir si le patient se juge comme amélioré ou non. Malgré ces données, le manque d’harmonisation dans le choix des scores rend difficile la comparaison de ces scores notamment pour les méta-analyses ou les revues de la littérature. Ainsi pour cette thèse, une cohorte prospective de patients souffrant d’une arthrose de hanche et du genou a été créée afin : 1) de valider différents scores, 2) de définir la DMCI pour ces scores en France, 3) de permettre d’obtenir par un processus statistique, un moyen de connaitre le résultat d’un score en n’ayant à sa disposition que le résultat d’un autre score (mapping ou crosswalk). A l’occasion de cette thèse, les score HOOS-12 et KOOS-12, version réduite à 12 items du score HOOS (40 items) et du score KOOS (42 items) ont bénéficié d’une validation en français. La DMCI pour les scores HOOS et Oxford-12 hanche a pu être définie. Cette thèse a permis d’explorer une option de calcul de la DMCI en utilisant un item du score lui-même permettant d’envisager l’usage de la méthode des ancres en l’absence d’une question supplémentaire. Différentes méthodes de mapping ont été testées sur le score HOOS et tous ses dérivés afin de définir la méthode la plus optimale ainsi que le score le plus adapté pour obtenir un mapping avec le score Oxford-12. La méthode equipercentile a permis de réaliser une table de conversion entre le score Oxford-12 Hanche et le score HOOS-12
Patient reported outcome measurement scores (PROMs) are part of modern patient’s assessment. For example, in orthopedics they are used to define a baseline level and after a surgical or medical treatment, to define an improvement. These scores require a validation procedure (internal and external validity, Responsiveness, reliability, translation in different languages, assessment of floor and ceiling effect…). Patient’s satisfaction after a surgical procedure can be measured through MCID (Minimal Clinical Important Difference). The MCID represents the minimum clinically relevant difference for the patient but is different between countries. MCID can be calculated by various methods, including the anchor method requiring an additional question to define the improvement. Despite these data, the lack of harmonization in the choice of scores makes difficult to compare these scores, especially for meta-analyzes or systematic reviews. In this thesis, a prospective hip and knee cohort was created to: 1) validate different scores, 2) define the MCID of these scores in France, 3) define a statistical process to deduct a score result from another score (Mapping or crosswalk).The HOOS-12 and KOOS-12 scores (abridged versions to 12 items of the HOOS score (40 items) and the KOOS score (42 items)) were validated in French. The MCID for HOOS and hip Oxford scores has been defined for the French population. An option to calculate the MCID using a score item itself was explored, which allowed us to consider using the anchor method in the absence of additional questions. Different methods have been tested to define the most optimal method and the most optimal score for mapping between HOOS and Oxford-12. A conversion table was created between the Oxford-12 hip score and HOOS-12 by the equipercentile method
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George, Susan. "The distribution of DMC1 epitopes in lilies with normal and aberrant meioses". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58737.pdf.

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Fick, Rutger. "Modélisation avancée du signal dMRI pour la caractérisation de la microstructure tissulaire". Thesis, Université Côte d'Azur (ComUE), 2017. http://www.theses.fr/2017AZUR4006/document.

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Cette thèse est dédiée à améliorer la compréhension neuro-scientifique à l'aide d'imagerie par résonance magnétique de diffusion (IRMd). Nous nous concentrons sur la modélisation du signal de diffusion et l'estimation par IRMd des biomarqueurs liés à la microstructure, appelé «Microstructure Imaging». Cette thèse est organisée en trois parties. Dans partie I nous commençons par la base de l'IRMd et un aperçu de l'anisotropie en diffusion. Puis nous examinons la plupart des modèles de microstructure utilisant PGSE, en mettant l'accent sur leurs hypothèses et limites, suivi par une validation par l'histologie de la moelle épinière de leur estimation. La partie II présente nos contributions à l'imagerie en 3D et à l’estimation de microstructure. Nous proposons une régularisation laplacienne de la base fonctionnelle MAP, ce qui nous permet d'estimer de façon robuste les indices d'espace q liés au tissu. Nous appliquons cette approche aux données du Human Connectome Project, où nous l'utilisons comme prétraitement pour d'autres modèles de microstructure. Enfin, nous comparons les biomarqueurs dans une étude ex-vivo de rats Alzheimer à différents âges. La partie III présente nos contributions au représentation de l’espace qt - variant sur l'espace q 3D et le temps de diffusion. Nous présentons une approche initiale qui se concentre sur l'estimation du diamètre de l'axone depuis l'espace qt. Nous terminons avec notre approche finale, où nous proposons une nouvelle base fonctionnelle régularisée pour représenter de façon robuste le signal qt, appelé qt-IRMd. Ce qui permet l'estimation des indices d’espace q dépendants du temps, quantifiant la dépendance temporelle du signal IRMd
This thesis is dedicated to furthering neuroscientific understanding of the human brain using diffusion-sensitized Magnetic Resonance Imaging (dMRI). Within dMRI, we focus on the estimation and interpretation of microstructure-related markers, often referred to as ``Microstructure Imaging''. This thesis is organized in three parts. Part I focuses on understanding the state-of-the-art in Microstructure Imaging. We start with the basic of diffusion MRI and a brief overview of diffusion anisotropy. We then review and compare most state-of-the-art microstructure models in PGSE-based Microstructure Imaging, emphasizing model assumptions and limitations, as well as validating them using spinal cord data with registered ground truth histology. In Part II we present our contributions to 3D q-space imaging and microstructure recovery. We propose closed-form Laplacian regularization for the recent MAP functional basis, allowing robust estimation of tissue-related q-space indices. We also apply this approach to Human Connectome Project data, where we use it as a preprocessing for other microstructure models. Finally, we compare tissue biomarkers in a ex-vivo study of Alzheimer rats at different ages. In Part III, we present our contributions to representing the qt-space - varying over 3D q-space and diffusion time. We present an initial approach that focuses on 3D axon diameter estimation from the qt-space. We end with our final approach, where we propose a novel, regularized functional basis to represent the qt-signal, which we call qt-dMRI. Our approach allows for the estimation of time-dependent q-space indices, which quantify the time-dependence of the diffusion signal

Libri sul tema "DMCI":

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Jorro, Francisco Aura. Diccionario micénico (DMic.). Madrid: Consejo Superior de Investigaciones Cientifícas, Instituto de Filología, 1985.

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Gessel, John. DMI mathematics systems. Monterey, Calif. :(Del Monte Research Park, 2500 Garden Rd., Monterey 93940): CTB/McGraw-Hill, 1985.

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Islam, Dunia Melayu Dunia. Wajah wajah DMDI (Dunia Melayu Dunia Islam: Faces of DMDI : (Malay and Islamic world). Melaka, Malaysia: Dunia Melayu Dunia Islam, 2014.

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Lummis, Michael. DMC: Devil may cry. Indianapolis, Ind: DK/BradyGames, 2012.

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Pappas, Tasso. To be or not to be a DMC? [S.l.]: SITE, 1996.

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Spona, Helma. Panasonic Lumix DMC-FZ100: Mit 12-seitiger Klappkarte. [S.l.]: Markt+Technik Verlag, 2012.

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Matsumoto, Brian. The Panasonic Lumix DMC-G2: The unofficial quintessential guide. Santa Barbara, CA: Rocky Nook, 2011.

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Adler, B. Tougher than leather: The authorized biography of RUN-DMC. New York: Signet, 1987.

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Maier, Rolf. Development of a river navigation pilot using a DMC controller. Manchester: UMIST, 1997.

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DMC. King of rock: Respect, responsibility, and my life with Run-DMC. New York: St. Martin's Press, 2001.

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Capitoli di libri sul tema "DMCI":

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Metze, Dieter, Tam Nguyen, Birgit Haack, Alexander K. C. Leung, Noriko Miyake, Naomichi Matsumoto, A. J. Larner et al. "DMC". In Encyclopedia of Molecular Mechanisms of Disease, 540–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6872.

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Mazin, Alexander V., e Olga M. Mazina. "Rad51 and Dmc1 Recombinases". In Molecular Life Sciences, 1009–16. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_67.

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Gratz, Joseph C. "The DMCA Safe Harbor". In The Routledge Companion to Copyright and Creativity in the 21st Century, 289–92. New York, NY; Milton Park, Abingdon, Oxon: Routledge, 2021.: Routledge, 2020. http://dx.doi.org/10.4324/9781315658445-42.

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Reed, Christopher S. "The DMCA Safe Harbor". In The Routledge Companion to Copyright and Creativity in the 21st Century, 293–97. New York, NY; Milton Park, Abingdon, Oxon: Routledge, 2021.: Routledge, 2020. http://dx.doi.org/10.4324/9781315658445-43.

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Mazin, Alexander V., e Olga M. Mazina. "Rad51 and Dmc1 Recombinases". In Molecular Life Sciences, 1–8. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_67-2.

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Donzellini, Giuliano, Andrea Mattia Garavagno e Luca Oneto. "La Programmazione Del DMC8". In Introduzione al Progetto di Sistemi a Microprocessore, 191–321. Milano: Springer Milan, 2020. http://dx.doi.org/10.1007/978-88-470-4004-5_3.

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Morton-Jones, David H., e John W. Ellis. "DMC Vehicle Headlamps". In Polymer Products, 196–210. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4101-4_18.

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Larbani, Moussa, e Po-Lung Yu. "Expansion of Habitual Domains and DMCS". In Wonderful Solutions and Habitual Domains for Challenging Problems in Changeable Spaces, 89–121. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-1981-4_4.

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Larbani, Moussa, e Po-Lung Yu. "Innovation Dynamics as a DMCS Problem". In Wonderful Solutions and Habitual Domains for Challenging Problems in Changeable Spaces, 241–55. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-1981-4_9.

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Huang, Wei, Zhe Wang e Jie Ma. "Design of DMPI on DAWNING-3000". In Recent Advances in Parallel Virtual Machine and Message Passing Interface, 314–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45825-5_48.

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Atti di convegni sul tema "DMCI":

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Trucco, Paolo, Pietro Maggia e Boris Petrenj. "Adapting Public Transport to COVID-19 Contingencies: Evaluating Unlock Policies in the Metropolitan Area of Milan Through DMCI Simulation". In Proceedings of the 29th European Safety and Reliability Conference (ESREL). Singapore: Research Publishing Services, 2020. http://dx.doi.org/10.3850/978-981-14-8593-0_5706-cd.

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Drobyshevski, Y., H. Wadhwa e J. R. Whelan. "Response Based Design Metocean Conditions for an FPSO by the Extremum Search Within Joint Metocean PDF". In ASME 2015 34th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/omae2015-41658.

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Abstract (sommario):
The response based analysis of a floating system aims at the prediction of extreme N-year return period responses by analysing their statistics in site-specific metocean conditions. After the extreme responses have been determined the inverse problem is solved: the most probable design metocean conditions (DMC) should be determined which cause these responses. The most probable DMC associated with a given response can be determined by using the joint probability density function (PDF) of metocean parameters. Mathematically, the most probable DMC is equivalent to a “design point”, at which the joint metocean PDF has a conditional maximum. This paper presents a method for finding the most probable DMC by the extremum search. Several numerical examples are presented to demonstrate finding the most probable DMCs for typical responses of an FPSO in North Sea environment, including global motions, wave loads, turret motions and relative wave motions. The most probable DMCs are found by the search process implemented in the space of physical metocean variables, which allows for easy interpretation of the results and exploring the response sensitivity to variability of metocean parameters.
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Drobyshevski, Y., J. R. Whelan, H. Wadhwa e V. Anokhin. "Determination of Design Metocean Conditions by Response Based Analysis". In ASME 2014 33rd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/omae2014-24657.

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Response Based Analysis (RBA) aims at prediction of the long term distributions of critical responses such as motions, accelerations, wave loads, which have significant impact on the design of a floating system. As compared with the conventional analysis, which predicts the responses of the facility to the N-year return period metocean conditions, RBA provides directly the N-year return period responses by analysing the statistics of their long term time histories. Another outcome of RBA is the Design Metocean Conditions (DMCs) which are combinations of sea state, wind and current causing the corresponding N-year response. The knowledge of the DMCs enables the more detail time domain analysis and model tests to be performed for a set of critical combinations of metocean parameters. It also enables all the associated responses to be determined. The RBA framework is generally well addressed in the literature, but the DMC identification methods are not necessarily clearly established. The objective of this paper is to present the theoretical background, numerical method and an example for the determination of the N-year return period responses and the associated DMCs for a floating facility. The method includes prediction of the N-year response, identification of the metocean combinations within the available time history which produce this response, determination of the required percentile of the short term response to match the N-year response, and the search for the most probable DMC within the joint probability density of the metocean parameters. Features of the method are discussed and results are presented for several critical responses of a weather vaning vessel.
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Xu, Cai, Ziyu Guan, Wei Zhao, Yunfei Niu, Quan Wang e Zhiheng Wang. "Deep Multi-View Concept Learning". In Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California: International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/402.

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Abstract (sommario):
Multi-view data is common in real-world datasets, where different views describe distinct perspectives. To better summarize the consistent and complementary information in multi-view data, researchers have proposed various multi-view representation learning algorithms, typically based on factorization models. However, most previous methods were focused on shallow factorization models which cannot capture the complex hierarchical information. Although a deep multi-view factorization model has been proposed recently, it fails to explicitly discern consistent and complementary information in multi-view data and does not consider conceptual labels. In this work we present a semi-supervised deep multi-view factorization method, named Deep Multi-view Concept Learning (DMCL). DMCL performs nonnegative factorization of the data hierarchically, and tries to capture semantic structures and explicitly model consistent and complementary information in multi-view data at the highest abstraction level. We develop a block coordinate descent algorithm for DMCL. Experiments conducted on image and document datasets show that DMCL performs well and outperforms baseline methods.
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"Preface to DMMI 2014". In 2014 IEEE International Conference on Data Mining Workshop (ICDMW). IEEE, 2014. http://dx.doi.org/10.1109/icdmw.2014.199.

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Polyanskiy, Yury. "On dispersion of compound DMCs". In 2013 51st Annual Allerton Conference on Communication, Control, and Computing (Allerton). IEEE, 2013. http://dx.doi.org/10.1109/allerton.2013.6736501.

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Nasser, Rajai, e Emre Telatar. "Polarization theorems for arbitrary DMCs". In 2013 IEEE International Symposium on Information Theory (ISIT). IEEE, 2013. http://dx.doi.org/10.1109/isit.2013.6620436.

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Akkaya, Ali, e Tuna Tugcu. "dMCS: Distributed Molecular Communication Simulator". In 8th International Conference on Body Area Networks. ACM, 2013. http://dx.doi.org/10.4108/icst.bodynets.2013.253576.

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"DMC Organizing Committee". In 2008 IEEE 17th Workshop on Enabling Technologies: Infrastructure for Collaborative Enterprises. IEEE, 2008. http://dx.doi.org/10.1109/wetice.2008.71.

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"DMC Organzing Committee". In 2009 18th IEEE International Workshops on Enabling Technologies: Infrastructures for Collaborative Enterprises. IEEE, 2009. http://dx.doi.org/10.1109/wetice.2009.54.

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Rapporti di organizzazioni sul tema "DMCI":

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Dray, Eloise, Myun Hwa Dunlop, Liisa Kauppi, Joseph San San Filippo, Claudia Wiese, Miaw-Sheue Tsai, Sead Begovic et al. Molecular Basis for Enhancement of the Meiotic DMCI Recombinase by RAD51AP1. Office of Scientific and Technical Information (OSTI), novembre 2010. http://dx.doi.org/10.2172/1011037.

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Saleh, Tarik A., Matthew Estevan Quintana e Tobias J. Romero. UCSB ATR-­NSUF Irradiation DMC Sample Inspection Report. Office of Scientific and Technical Information (OSTI), febbraio 2015. http://dx.doi.org/10.2172/1170627.

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Abercrombie-Thomas, Patrice L., James H. Buchanan, Ann Brozena e David E. Tevault. Selected Thermophysical Properties of 2,2 Dimethylcyclopentyl Methylphosphonofluoridate (GP) and 2,2 Dimethylcyclopentanol (DMCP). Fort Belvoir, VA: Defense Technical Information Center, settembre 2016. http://dx.doi.org/10.21236/ad1018281.

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ARMY WAR COLL CARLISLE BARRACKS PA. Department of the Navy (DON) Data Management and Interoperability (DMI) Strategic Plan. Fort Belvoir, VA: Defense Technical Information Center, novembre 2000. http://dx.doi.org/10.21236/ada389811.

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Bruggeman, David Alan, e Carl Mazzola. LANL Meteorological Program Self-Assessment to Address Recommendations from the 2015 DOE Meteorological Coordinating Council (DMCC) Assist Visit. Office of Scientific and Technical Information (OSTI), gennaio 2019. http://dx.doi.org/10.2172/1493526.

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Guidotti, R. A., e B. J. Johnson. Temperature effects on the performance of PMAN-derived carbon anodes in 1M LiPF{sub 6}/EC-DMC solution. Office of Scientific and Technical Information (OSTI), aprile 1998. http://dx.doi.org/10.2172/672103.

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Trenchard, Michael E., Stephanie A. Myrick, Maura C. Lohrenz, Marlin L. Gendron e Jessica L. Watkins. Moving-Map Composers System Version 3.4P Acceptance Test Procedures Developed for the Finnish Air Force Modification for FIAF MMC System Without DMUI/DMU. Fort Belvoir, VA: Defense Technical Information Center, novembre 2004. http://dx.doi.org/10.21236/ada429998.

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Guidotti, R. A., e B. J. Johnson. Effect of solution additives on the performance of PMAN carbon anodes in 1M LiPF{sub 6}/EC-DMC solutions. Office of Scientific and Technical Information (OSTI), dicembre 1996. http://dx.doi.org/10.2172/486068.

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Guidotti, R. A. Effects of partial oxidation of PMAN carbon on their performance as anodes in 1M LiPF{sub 6}/EC-DMC solutions. Office of Scientific and Technical Information (OSTI), dicembre 1996. http://dx.doi.org/10.2172/486069.

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Shimizu, Yusuke, Satoshi Kato e Takashi Fujita. Study on PCCI Engine With Direct Fuel Injection Impingement and Distribution (OSKA) Systems~Investigation on Combustion Chamber Shapes and DMC-Added Fuel. Warrendale, PA: SAE International, settembre 2005. http://dx.doi.org/10.4271/2005-08-0439.

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