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Tesi sul tema "Eosinophil"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

Konikoff, Michael R. "Non-Invasive Biomarkers of Eosinophilic Esophagitis: Blood Eosinophil Level, Eosinophil-Derived Neurotoxin, and Eotaxin-3." Cincinnati, Ohio : University of Cincinnati, 2006. http://www.ohiolink.edu/etd/view.cgi?acc_num=ucin1148043525.

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Thesis (M.S.)--University of Cincinnati, 2006.<br>Advisor: Dr. James E. Heubi. Title from electronic thesis title page (viewed June 3, 2009). Includes abstract. Keywords: Eosinophilic esophagitis; biomarker; eosinophil; eosinophil-derived neurotoxin; eotaxin-3. Includes bibliographical references.

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2

Seton, Kristina. "Eosinophil Apoptosis." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3427.

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<p>Apoptosis or programmed cell death is crucial for the resolution of inflammation, and phagocytosis of apoptotic cells initiates the release of actively anti-inflammatory responses from the phagocytes. Eosinophils are one of the most potent inflammatory cells in the body and is involved in a number of diseases, most commonly associated with parasitic infections and allergic diseases. Apoptosis in eosinophils is therefore one of the most important systems to avoid inflammation. This aim of the present investigation was to examine the mechanisms behind, and the consequences of this process in

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3

Dewson, Grant. "Regulation of human eosinophil apoptosis." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29380.

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Eosinophils play a pivotal role in the pathogenesis of asthma and allergic disease. The accumulation and persistence of eosinophils at sites of inflammation are mediated at least in part by the extended survival of eosinophils in response to circulating hematopoietins IL-3, IL-5 and GM-CSF. The apoptosis and subsequent clearance of eosinophils without histotoxic mediator release is thought to be crucial in the resolution of airway inflammation in asthma. This study characterised the morphological and biochemical events of human eosinophil apoptosis in vitro and investigated the mechanism by wh

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4

Al-Khabuli, JumaÊ¾. "Role of eosinophil in oral squamous cell carcinoma and traumatic ulcerative granuloma with stromal eosinophilia." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418167.

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5

Humbles, Alison Anita. "The relationship between the generation of an eosinophil-selective chemoattractant, ecotoxin and eosinophil accumulation in vivo." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267879.

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6

Byström, Jonas. "Eosinophil Cationic Protein : Expression Levels and Polymorphisms." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2059.

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<p>The eosinophil cationic protein (ECP) is usually associated with the eosinophil granulocyte. In this thesis the presence and production of this protein has been studied in two other cells. The circulating monocyte was found to contain ECP mRNA and small amounts of ECP, one thousand times less than that found in the eosinophil. The production decreased by differentiation of the myelomonoblastic cell line U937 into a macrophage phenotype. Submucosal lung macrophages did not stain for ECP and alveolar macrophages did not contain ECP mRNA. The circulating neutrophil contains ECP at a level hund

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7

Admiraal, Claudia Johanna. "Eosinophil degranulation as an allergy activation marker." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/59048.

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8

Sandig, Hilary. "CRTH2 and its ligands in eosinophil biology." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430475.

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9

Hallsworth, Matthew Pearce. "GM-CSF and eosinophil survival in asthma." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341883.

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10

Flemmig, Jörg, Johannes Remmler, Josefin Zschaler, and Jürgen Arnhold. "Detection of the halogenating activity of heme peroxidases in leukocytes by aminophenyl fluorescein." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-201836.

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The formation of hypochlorous and hypobromous acids by heme peroxidases is a key property of certain immune cells. These products are not only involved in defense against pathogenic microorganisms and in regulation of inflammatory processes, but contribute also to tissue damage in certain pathologies. After a short introduction about experimental approaches for the assessment of the halogenating activity in vitro and in cell suspensions, we are focusing on novel applications of fluorescent dye systems to detect the formation of hypochlorous acid (HOCl) in leukocytes. Special attention is direc

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11

Egesten, Arne. "On storage and release of eosinophil granule proteins." Lund : Division of Hematology, Dept. of Medicine, University of Lund, 1995. http://catalog.hathitrust.org/api/volumes/oclc/39104245.html.

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12

Kottyan, Leah Claire. "Airway Acidification in Asthma." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1280778640.

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13

Felton, Jennifer Marie. "Investigation of the role of Mcl-1 and Mer in the regulation of eosinophil apoptosis and efferocytosis." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28833.

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Abstract (sommario):

Regulation of the inflammatory response is essential for the successful resolution of inflammation, and restoration of normal tissue homeostasis. Eosinophils are granulocytic cells of the innate immune system historically considered to be primarily involved in the defence against parasitic infection. Eosinophils are also key effector cells in the allergic inflammatory response, initiation of which is associated with the recruitment and activation of eosinophils culminating in the release of their intracellular granule contents. Eosinophil granules contain a range of cytotoxic proteins (major b

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14

Costain, Darren James. "Hypodense eosinophil tumouricidal activity, an in vitro analysis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0022/MQ36419.pdf.

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15

Jenkins, Gareth Raymond. "Neutrophil and eosinophil mediated inflammation in childhood asthma." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407789.

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16

Ali, Shahina. "Molecular mechanisms of eosinophil recruitment to breast carcinoma sites." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ64939.pdf.

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17

De, Souza Patricia Manuela. "Signal transduction mechanisms regulating human eosinophil and neutrophil apoptosis." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397695.

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18

Palframan, Roger Thomas. "Regulation of acute eosinophil mobilisation from the bone marrow." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314279.

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19

Teran, Luis Manuel. "Identification of neutrophil and eosinophil chemotactic factors in asthma." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295930.

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20

Bourne, Andrew D. "Investigation of transduction mechanisms for agonist-induced eosinophil responses." Thesis, University of Bath, 1995. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296317.

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21

Davis, Benjamin. "Genetic and Functional Analysis of Calpain-14 in Eosinophilic Esophagitis." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1447688593.

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22

Kämpe, Mary. "Eosinophil Inflammation in Allergic Disease : Clinical and experimental studies in allergic asthma and allergic rhinitis." Doctoral thesis, Uppsala universitet, Lungmedicin och allergologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-130949.

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Abstract (sommario):

Allergic diseases are chronic inflammatory conditions, characterised by eosinophil inflammation systemically and in target organs, where cytotoxic granule proteins are responsible for tissue injury. Allergic rhinitis is known to be a risk factor for the development of asthma, yet not all with rhinitis develop asthma. The overall aim was to investigate the involvement of eosinophils in allergic rhinitis and allergic asthma in vivo and in experimental settings, with a focus on differences between rhinitis and asthma. Birch pollen allergy was used as a model and patients were studied during polle

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23

Flemmig, Jörg, Johannes Remmler, Josefin Zschaler, and Jürgen Arnhold. "Detection of the halogenating activity of heme peroxidases in leukocytes by aminophenyl fluorescein." Free radical research (2015) 49, S. 768-776, 2015. https://ul.qucosa.de/id/qucosa%3A14678.

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Abstract (sommario):

The formation of hypochlorous and hypobromous acids by heme peroxidases is a key property of certain immune cells. These products are not only involved in defense against pathogenic microorganisms and in regulation of inflammatory processes, but contribute also to tissue damage in certain pathologies. After a short introduction about experimental approaches for the assessment of the halogenating activity in vitro and in cell suspensions, we are focusing on novel applications of fluorescent dye systems to detect the formation of hypochlorous acid (HOCl) in leukocytes. Special attention is direc

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24

Sanmugalingam, Devika. "Human lung mast cell and eosinophil adhesion to bronchial epithelium." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29394.

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Abstract (sommario):

Asthma is initiated at the mucosal surface upon aeroallergen exposure and mast cell activation. Release of eosinophil cationic proteins is thought to be responsible for epithelial damage. In this study, human peripheral blood eosinophil and human lung mast cell (HLMC) adhesion to bronchial epithelium were investigated. A high proportion of HLMC adhered to epithelial cell monolayers compared to eosinophils. In both cases, adhesion was cation-independent, and was not inhibited by function-blocking ICAM-1 mAb, despite increased basal epithelial ICAM-1 expression upon cytokine activation. HLMC adh

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25

McNulty, Clare A. "Studies on the molecular basis of eosinophil adhesion to endothelium." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29391.

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Abstract (sommario):

Selective adhesion may be important for the preferential accumulation of eosinophils in asthma and allergic diseases. The Stamper-Woodruff frozen section assay (FSA) was used to define the adhesion of human peripheral blood eosinophils and neutrophils to endothelium in a model of chronic airway inflammation, the nasal polyp. Eosinophil and neutrophil adhesion to nasal polyp endothelium (NPE) was (32 integrin-dependent. Eosinophil adhesion was inhibited to a lesser extent by mAbs against pi integrins and VCAM-1. Adhesion of both eosinophils and neutrophils to NPE was activation-dependent. as sh

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26

Turner, Darryl Griffith. "The characterisation of haeomonchus contortus products which affect eosinophil activity." Thesis, Edinburgh Napier University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506341.

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27

Foweraker, J. E. "A study of eosinophil granule proteins and in vitro degranulation." Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377204.

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28

Maziero, Aline Mendes 1981. "Inibição da agregação de plaquetas humanas por eosinófilos." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312670.

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Orientador: Gilberto De Nucci<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-24T16:13:57Z (GMT). No. of bitstreams: 1 Maziero_AlineMendes_D.pdf: 2175096 bytes, checksum: b3e712ed8baf6a7f7d4ef12131b9e85a (MD5) Previous issue date: 2014<br>Resumo: Os eosinófilos participam de processos inflamatórios e alérgicos. Estando relacionados com o sistema de imunidade inata do organismo, eles representam uma linha fundamental de defesa contra invasão microbiana e, quando ativados, produzem uma série de mediadores solúveis qu

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29

Lampinen, Maria. "Cytokine-regulated eosinophil migration in inflammatory disorders : Clinical and experimental studies." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-528.

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<p>The accumulation of eosinophil granulocytes (EOS) at sites of inflammation is a common feature of astma, allergic rhinitis and inflammatory bowel disease. The aim of the present investigation was to study the mechanisms involved in this accumulation.</p><p>Bronchoalveolar lavage (BAL) fluid obtained from patients with birch-pollen allergy lavaged during season exhibited increased eosinophil chemotactic activity compared with pre-season BAL fluid from the same patients. We identified IL-5, IL-8 and RANTES as the main eosinophil chemotactic agents in the BAL fluid. Only EOS from allergic dono

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30

Nopp, Anna. "Characterisation of eosinophil activity markers : relation to allergic inflammation and apoptosis /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-129-2.

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31

Farahi, Neda. "Characterisation of a pulmonary artery endothelium cell-derived eosinophil survival activity." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615872.

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32

Lee, Elaine. "The effect of leukotriene inhibition in neutrophil, eosinophil and monocyte apoptosis." Thesis, University of Sunderland, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399656.

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33

Grix, Suzanna Peta. "Pharmacological characterisation of the role of Ca²⁺ in human eosinophil activation." Thesis, University of Bath, 1995. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295455.

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34

Ferreira, Lauren. "Cytokine properties of CD23 on human Eosinophilic cells." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/503.

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Abstract (sommario):

CD23, the low affinity IgE receptor, is expressed by various cell types and has numerous functions depending on the form of the protein, its interaction with various ligands and the type of cell involved. CD23 is pivotal in the regulation of IgE, with the soluble form involved in up-regulation, while the membrane bound form is involved in the down-regulation. It is clear why it is believed to be a central molecule in allergic responses, and a therapeutic target for the treatment of allergic disease. In this study a recombinant form of the entire extracellular domain of the protein, exCD23, was

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35

Toor, Iqbal Singh. "Investigating the role of eosinophils in cardiac remodelling following myocardial infarction." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31187.

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Myocardial infarction (MI) occurs following acute thrombotic occlusion of a coronary artery, and triggers a robust inflammatory response. Within hours, neutrophils are recruited to the infarcted myocardium followed by the infiltration of pro-inflammatory Ly6Chi monocytes. Transition from the pro-inflammatory macrophage phenotype (M1) to an anti-inflammatory, pro-resolution phenotype (M2-like) is critical to successful infarct healing. Interventions that polarize macrophages towards an anti-inflammatory 'M2-like' phenotype improve infarct healing in the experimental MI mouse model and reduce su

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36

Lilliehöök, Inger. "Studies of blood eosinophil and neutrophil granulocytes in healthy and diseased dogs /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5409-3.pdf.

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37

Warren, David John. "Studies on an eosinophil differentiation factor produced by a T-hybrid line." Thesis, Brunel University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290954.

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38

Li, Ming-Shi. "Structure and expression of the gene encoding human eosinophil major basic protein." Thesis, St George's, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307257.

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39

Stevenson, Lesley Margaret. "Studies on the role of the eosinophil leukocyte in ovine nematode infections." Thesis, Edinburgh Napier University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386225.

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40

Maxwell, M. H. "Studies on the avian eosinophil leucocyte with special reference to its stimulation." Thesis, University of Strathclyde, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371960.

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41

Song, Wei. "MASS SPECTROMETRY-BASED HIGH THROUGHPUT APPROACH FOR IDENTIFICATION OF MOLECULAR MODIFICATION OF OXIDATIVE PROCESS IN RESPIRATORY." Cleveland State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1226685494.

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42

Guay, Caroline. "Expression et rôle d'une nouvelle protéase à sérine: l'«eosinophil serine protease»-1." Thesis, Université Laval, 2007. http://www.theses.ulaval.ca/2007/24677/24677.pdf.

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43

Ara, Bilquis Ferdous. "Direct and eosinophil dependent mechanisms underlying mistletoe therapy in the treatment of melanoma." Doctoral thesis, importedStudentThesis, 2017. https://researchprofiles.canberra.edu.au/en/studentTheses/8c55390e-5b70-412c-9762-8218bc083e58.

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44

NOEL, RICHARD JOSEPH. "DEMOGRAPHIC ANALYSIS OF ESOPHAGITIS: A POPULATION-BASED STUDY." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1085675249.

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45

Davies, Dawn. "The role of calcitonin gene related peptide in the activation of the eosinophil leukocyte." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240801.

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46

Greenaway, Elona Clare. "Protein kinase C in eosinophils from normal and allergic ponies." Thesis, Royal Veterinary College (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367564.

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47

Stamatiou, Panagiota. "5-oxo-ETE and its effect on eosinophil recruitment in the Brown Norway rat lung." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ50886.pdf.

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48

Stamatiou, Panagiota. "5-oxo-ETE and its effect on eosinophil recruitment in the Brown Norway rat lung." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21646.

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Abstract (sommario):

The 5-lipoxygenase product 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is a potent eosinophil chemoattractant in vitro. To determine whether it is active in vivo, 5-oxo-ETE was administered intratracheally to BN rats and pulmonary eosinophils were immunostained with an antibody to major basic protein. 5-Oxo-ETE induced a dramatic increase in eosinophils, which reached maximal levels (5 times control) between 15 and 24 h following administration, and thereafter declined. LTB4 had a similar effect to 5-oxo-ETE but appeared to be somewhat less effective. In contrast, LTD4 and LTE4 were inac

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49

Lavinskienė, Simona. "Peripheral blood neutrophil and eosinophil activity during allergen-induced late-phase airway inflammation in asthma." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2015. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20150106_083713-90371.

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There is no doubt that eosinophils and neutrophils are important cells participating in asthma pathogenesis. The most prominent feature reflecting asthma pathogenesis is late-phase airway inflammation, which occurs a few hours after allergen inhalation. The worldwide published studies on asthma show that most attention is paid to individual, not complex, functions of neutrophils and eosinophils in the airways. Moreover, associations between peripheral blood neutrophil and eosinophil activity and infiltration of these cells in the airways during asthma have not been com¬pletely elucidated yet.

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50

Milne, Elodie Marie. "Characterisation of the receptor subtype and mechanism by which PGE2 inhibits neutrophil and eosinophil activation." Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/21424.

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The aim of this thesis was to identify the EP-receptor subtype(s) mediating: - inhibition of the superoxide anion generation in human neutrophils stimulated by formyl methionyl leucine phenylalanine (FMLP), - inhibition of eosinophil cationic protein (ECP) release in a mixed population of PMN stimulated by FMLP, - inhibition of ECP release of superoxide anion generation in a pure population of human eosinophils stimulated by FMLP and C5a respectively, Another part of this study was to test the hypothesis that cAMP is the second messenger mediating inhibition of neutrophil and eosinophil activa

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