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Articoli di riviste sul tema "Fetal malnutrition Complications"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 28 gennaio 2023

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1

Dolgova, Yu S., D. R. Eremeeva, and M. S. Zainulina. "Risks of reproductive loss and placenta-mediated pregnancy complications in women with antiphospholipid antibodies." Obstetrics, Gynecology and Reproduction 14, no. 6 (January 11, 2021): 592–601. http://dx.doi.org/10.17749/2313-7347/ob.gyn.rep.2020.181.

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Introduction. Antiphospholipid syndrome (AРS) is a multisystem disease characterized by elevated levels of antiphospholipid antibodies (AРA), arterial and/or venous thrombosis, thrombocytopenia, and habitual miscarriage. Various AРA types have multifactorial and indirect effects on pregnancy course from the earliest stages, leading to termination of pregnancy and putting the prerequisites for further obstetric complications. Aim: determine rate and relative risk of pregnancy complications in AРA carriers. Materials and Methods. The retrospective study, conducted between 2017 and 2019, included

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Pires, Isadora Garcia, Iluskhanney Gomes de Medeiros Nóbrega Miranda, Ingrid Rafaella Mauricio Silva Reis, and Juscelino Kubitschek Bevenuto Da Silva. "Doença falciforme, estado nutricional e sua relação com intercorrências obstétricas." STUDIES IN HEALTH SCIENCES 2, no. 2 (September 17, 2021): 25–37. http://dx.doi.org/10.54018/shsv2n2-001.

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A anemia falciforme (AF) é uma doença autossômica recessiva, que leva à produção de hemoglobina anormal, denominada hemoglobina S (HbS). Seus portadores sofrem com o crescimento deficiente, desde a infância, além de disfunções endócrinas, baixo consumo alimentar, alto requerimento energético, deficiência de minerais, que podem resultar em desnutrição. Durante a gestação, está associada ao aumento de complicações relacionadas à própria doença, morbimortalidade materna e perinatal mais elevada, nascimento de crianças com baixo peso e maiores taxas de complicações infecciosas puerperais. O objeti

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Mikhaylin, Yevgeniy Sergeyevich, Lada Anatolyevna Ivanova, and Aleksey Gennadyevich Savitskiy. "Comparative characteristic of pregnancy and delivery in adolescents and women of average reproductive age." Journal of obstetrics and women's diseases 63, no. 4 (September 15, 2014): 47–53. http://dx.doi.org/10.17816/jowd63447-53.

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The article provides a comparative characteristic the main clinical parameters of pregnancy and delivery in adolescents and women of average reproductive age. The results of this study generally confirm the literature data on the greater frequency of complications of pregnancy and childbirth in juvenile women than in women of average reproductive age. Thus, significantly more frequently in pregnant adolescents dated anemia, preeclampsia, fetal malnutrition, during delivery more frequently dated premature rupture of membranes, perineotomy and newborn injury. At the same time, significant differ

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Briana, Despina D., and Ariadne Malamitsi-Puchner. "Intrauterine growth restriction and adult disease: the role of adipocytokines." European Journal of Endocrinology 160, no. 3 (March 2009): 337–47. http://dx.doi.org/10.1530/eje-08-0621.

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Intrauterine growth restriction (IUGR) is the failure of the fetus to achieve his/her intrinsic growth potential, due to anatomical and/or functional disorders and diseases in the feto–placental–maternal unit. IUGR results in significant perinatal and long-term complications, including the development of insulin resistance/metabolic syndrome in adulthood.The thrifty phenotype hypothesis holds that intrauterine malnutrition leads to an adaptive response that alters the fetal metabolic and hormonal milieu designed for intrauterine survival. This fetal programming predisposes to an increased susc

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Brohi, Sumera, Shazia Ahmed Jatoi, Saeed U. Nisa Sangi, Shaista Tabasum Abro, Rukhsana Shaikh, and Ayesha Jalbani. "Prevalence of Teenage Pregnancy & Its Outcome at Shaikh Zaid Women Hospital Larkana." Pakistan Journal of Medical and Health Sciences 16, no. 5 (May 30, 2022): 1461–63. http://dx.doi.org/10.53350/pjmhs221651461.

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Background: Teenage adolescent pregnancy is an important community health issue globally. Research shows that mothers in teenage period are at a higher risk of maternal death and complications related with pregnancy in comparison to the mothers who are adult. Therefore, this research was directed to examine the sociodemographic profile and fetal and maternal outcomes related with teenage pregnancy and their comparison with mothers of 20-30 years of age. Study Design: A comparative cross-sectional study. Place and Duration: In the obstetrics and Gynecology department of Sheikh Zaid Women Hospit

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Brohi, Sumera, Shazia Ahmed Jatoi, Saeed U. Nisa Sangi, Shaista Tabasum Abro, Rukhsana Shaikh, and Ayesha Jalbani. "Prevalence of Teenage Pregnancy & Its Outcome at Shaikh Zaid Women Hospital Larkana." Pakistan Journal of Medical and Health Sciences 16, no. 5 (May 30, 2022): 1461–63. http://dx.doi.org/10.53350/pjmhs221651461.

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Background: Teenage adolescent pregnancy is an important community health issue globally. Research shows that mothers in teenage period are at a higher risk of maternal death and complications related with pregnancy in comparison to the mothers who are adult. Therefore, this research was directed to examine the sociodemographic profile and fetal and maternal outcomes related with teenage pregnancy and their comparison with mothers of 20-30 years of age. Study Design: A comparative cross-sectional study. Place and Duration: In the obstetrics and Gynecology department of Sheikh Zaid Women Hospit

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Zhuk, S. I., and O. D. Shchurevska. "Fetal macrosomia: obstetrical, psychological and social aspects." HEALTH OF WOMAN, no. 7(153) (September 29, 2020): 36–39. http://dx.doi.org/10.15574/hw.2020.153.36.

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One of the main markers of socially unfavorable pregnancy is anthropometric indicators of newborns. They reflect not only the narrow medical problems of complicated gestation but also social problems in general, the quality and access to the medical care. The objective: to determine the risk factors for fetal macrosomia in pregnancy with high levels of psychosocial stress. Materials and methods. The course of pregnancy and childbirth, demographic and medical risk factors for a fetal macrosomia were analyzed in 140 pregnant women with different levels of psychosocial stress. They were divided i

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Kachkovskii, M. A., O. V. Kosheleva, and G. M. Mingulova. "Liver diseases at new coronavirus infection in pregnant women of Samara region." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 11, no. 5 (October 27, 2021): 34–41. http://dx.doi.org/10.20340/vmi-rvz.2021.5.covid.1.

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The new coronavirus infection (COVID-19) is a life-threatening condition. The features of the treatment of COVID-19 in pregnant women are not sufficiently studied and contradictory, therefore, research in this area is relevant.Objective. Assess the presence of liver disease in pregnant women with COVID-19 infection during pregnancy and after childbirth, taking into account the treatment.Methods. A retrospective analysis of medical records of 43 pregnant women aged 19 to 39 years (mean age 29.1 ± 5.4 years) who were hospitalized with laboratory-confirmed COVID-19 infection was performed. The se

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Mishra, Seema Kumari, Roshan Pradhan, Roshan Pradhan, Hanoon P. Pokharel, and Surya B. Parajuli. "Maternal and Perinatal outcome in eclampsia at a teaching hospital of Eastern Nepal." Birat Journal of Health Sciences 5, no. 3 (December 30, 2020): 1186–90. http://dx.doi.org/10.3126/bjhs.v5i3.33692.

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Introduction: Eclampsia is a multisystem disorder with potential life-threatening complications that can result in significant maternal and fetal morbidity and mortality. The case fatality rate of eclampsia is 1.8% in developed countries, 17.7% in India and 13% in Nepal. The incidence of pre-eclampsia and eclampsia is high in developing countries due to hypoproteinemia, malnutrition and poor obstetric facilities. Objective: To assess the maternal and perinatal outcome in patients of eclampsia Methodology: This was a hospital based cross-sectional study where all the patients presen

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Kaminskyi, V. V., O. I. Zhdanovich, T. V. Kolomiychenko, and A. D. Derkach. "Pregnancy after influenza in the first trimester." HEALTH OF WOMAN, no. 7(153) (September 29, 2020): 14–18. http://dx.doi.org/10.15574/hw.2020.153.14.

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The endpoint of the negative impact of adverse processes in the mother’s body with influenza is the formation of placental insufficiency, the basis of which is a violation of the uteroplacental blood flow. The objective: to study the features of the course of pregnancy, the state of the fetus and the newborn after the influenza in the first trimester of pregnancy. Materials and methods. 120 women who had the influenza in the first trimester of pregnancy were examined. In 68 (56.7%) pregnant women signs of feto-placental dysfunction were observed, 2 groups were distinguished: the main group - 6

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Weckman, Andrea M., Chloe R. McDonald, Jo-Anna B. Baxter, Wafaie W. Fawzi, Andrea L. Conroy, and Kevin C. Kain. "Perspective: L-arginine and L-citrulline Supplementation in Pregnancy: A Potential Strategy to Improve Birth Outcomes in Low-Resource Settings." Advances in Nutrition 10, no. 5 (May 10, 2019): 765–77. http://dx.doi.org/10.1093/advances/nmz015.

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ABSTRACT The available data support the hypothesis that L-arginine or L-citrulline supplementation would be suitable for implementation in resource-constrained settings and will enhance placental vascular development and improve birth outcomes. In resource-constrained settings, the rates of adverse birth outcomes, including fetal growth restriction, preterm birth, and low birth weight, are disproportionately high. Complications resulting from preterm birth are now the leading cause of mortality in children <5 y of age worldwide. Despite the global health burden of adverse birth outcomes, fe

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Muratova, Nigora J., and Nargiza G. Shokirova. "TREATMENT OF PLACENTAL INSUFFICIENCY IN PREGNANT WOMEN WITH ANTIPHOSPHOLIPID SYNDROME AND VARICOSE VEINS." Oriental Journal of Medicine and Pharmacology 02, no. 02 (April 1, 2022): 46–54. http://dx.doi.org/10.37547/supsci-ojmp-02-02-06.

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In recent years, there has been an increase in the frequency of placental insufficiency (PI) in pregnant women with obstetric and somatic pathology, including in patients with varicose veins, especially in the presence of autoimmune antibodies of various etiologies. The antiphospholipid syndrome (APS) attracts more and more attention of scientists, which significantly increases both maternal and perinatal mortality [8, 9]. Most of the adverse outcomes in APS are associated with PI. One of the reasons for the development of PI are disorders of the hemostasis system in pregnant women with the pr

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Budhewar, Amita, Sunita Ubale, Mamta Anand, Priti Naykodi, and Jaynarayan Senapati. "Study of fetomaternal outcome in eclampsia." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 5 (April 27, 2022): 1555. http://dx.doi.org/10.18203/2320-1770.ijrcog20221293.

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Background: Eclampsia is preventable and treatable cause of maternal mortality and morbidity with poor fetomaternal outcomes in developing countries. Poor knowledge, lack of education, malnutrition and lack of antenatal care major causative factors for increase in eclampsia in developing countries.Methods: This was a retrospective single center observational study including 106 pregnant women with eclampsia in antenatal, intranatal and postnatal period over period of one year in our institute.Results: 106 women included in this study. In present study mean age of the study population was 25.41

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Moreno-Fernandez, Jorge, Julio J. Ochoa, Magdalena Lopez-Frias, and Javier Diaz-Castro. "Impact of Early Nutrition, Physical Activity and Sleep on the Fetal Programming of Disease in the Pregnancy: A Narrative Review." Nutrients 12, no. 12 (December 20, 2020): 3900. http://dx.doi.org/10.3390/nu12123900.

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Early programming is the adaptation process by which nutrition and environmental factors alter development pathways during prenatal growth, inducing changes in postnatal metabolism and diseases. The aim of this narrative review, is evaluating the current knowledge in the scientific literature on the effects of nutrition, environmental factors, physical activity and sleep on development pathways. If in utero adaptations were incorrect, this would cause a mismatch between prenatal programming and adulthood. Adequate caloric intake, protein, mineral, vitamin, and long-chain fatty acids, have been

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15

Chhetry, Manisha, Shanti Subedi, and Basudeb Banerjee. "Risk factors for post caesarean surgical site infection at a tertiary care center in Eastern Nepal." Journal of College of Medical Sciences-Nepal 13, no. 3 (October 19, 2017): 314–17. http://dx.doi.org/10.3126/jcmsn.v13i3.18402.

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Background & Objectives:Post cesarean surgical site infection (SSI) is one of the commonly encountered complications which considerably increase the burden to health care. It is caused due to the interplay of various patient related, procedure related and iatrogenic factors. This study aims at identifying common risk factors for post cesarean SSI at our centre.Materials & Methods:This was a prospective observational study conducted from July 2015 to December 2015, in which all patients who were admitted with post cesarean SSI or developed SSI during their stay were included and their r

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Suismaya, Ni Luh Gede Wahyuni, I. Made Kardana, and Kadek Deddy Ariyanta. "Annular pancreas in two cases after diamond-shaped anastomosis duodenoduodenostomy: case reports." Intisari Sains Medis 11, no. 2 (August 1, 2020): 445–51. http://dx.doi.org/10.15562/ism.v11i2.581.

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Background: Annular pancreas is an infrequent congenital disorder characterized as a partial or complete pancreatic tissue around the descending part of the duodenum. Prenatal control is essential in the early detection of the annular pancreas. Initial management might increase better prognosis. We report two cases of the annular pancreas in Sanglah General Hospital, Denpasar, Bali in 2016-2019 to describe the clinical characteristics and outcome of different ages in annular pancreas managed by diamond-shaped duodenoduodenostomy.Case Description: The first case was a six days old baby boy with

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Lassi, Zohra S., Zahra A. Padhani, Amna Rabbani, Fahad Rind, Rehana A. Salam, Jai K. Das, and Zulfiqar A. Bhutta. "Impact of Dietary Interventions during Pregnancy on Maternal, Neonatal, and Child Outcomes in Low- and Middle-Income Countries." Nutrients 12, no. 2 (February 19, 2020): 531. http://dx.doi.org/10.3390/nu12020531.

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Optimal nutrition plays a crucial role in pregnancy. Maternal malnutrition is a risk factor for maternal, fetal, and neonatal complications and is more prevalent in low and middle-income countries (LMICs). This review aims to study the effectiveness of antenatal macronutrient nutritional interventions on maternal, neonatal, and child outcomes. We searched the CENTRAL, PubMed, Embase, and other databases for randomized controlled trials and quasi-experimental designs on healthy pregnant women in LMICs. We also searched grey literature and reports from Google Scholar, Web of Science, and website

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Mariko, Seydou, Mamadou Haidara, Pierre Coulibaly, Mahamoud Coulibaly, Kalilou Samaké, Soumana Oumar Traoré, and Alou Samaké. "Severe Anemia during Pregnancy in the Maternity Ward of the Kalabancoro Reference Health Center." Scholars International Journal of Obstetrics and Gynecology 5, no. 4 (April 23, 2022): 192–97. http://dx.doi.org/10.36348/sijog.2022.v05i04.010.

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Introduction: The main objective was to determine the maternal and fetal consequences of severe anemia in pregnancy at the maternity ward of the Kalabancoro Reference Health Center. Methods: Our descriptive cross-sectional study with prospective data collection was conducted from January 1, 2019 to September 30, 2019 at the maternity ward of the Kalabancoro Health Center. Eligible patients were all consenting pregnant women presenting for prenatal consultation or in the delivery room in which the diagnosis of severe anemia was retained. The anemia was considered severe when the hemoglobin leve

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Lebovitz, Harold E. "Type 2 Diabetes: An Overview." Clinical Chemistry 45, no. 8 (August 1, 1999): 1339–45. http://dx.doi.org/10.1093/clinchem/45.8.1339.

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Abstract Type 2 diabetes is a heterogeneous disorder. Clinical expression of the disorder requires both genetic and environmental factors. One theory concerning its etiology is that it is the result of the evolution of a thrifty genotype that had survival benefits in the past but is detrimental in the current environment. An opposing theory is that it represents an adult metabolic response to fetal malnutrition. Hyperglycemia in type 2 diabetes results from absolute or relative insulin deficiency. Most often relative insulin deficiency is attributable to an inability to adequately compensate f

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Denkl, Barbara, Nada Cordasic, Hanna Huebner, Carlos Menendez-Castro, Marius Schmidt, Alexander Mocker, Joachim Woelfle, Andrea Hartner, and Fabian B. Fahlbusch. "No evidence of the unfolded protein response in the placenta of two rodent models of preeclampsia and intrauterine growth restriction." Biology of Reproduction 105, no. 2 (May 6, 2021): 449–63. http://dx.doi.org/10.1093/biolre/ioab087.

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Abstract In humans, intrauterine growth restriction (IUGR) and preeclampsia (PE) are associated with induction of the unfolded protein response (UPR) and increased placental endoplasmic reticulum (ER) stress. Especially in PE, oxidative stress occurs relative to the severity of maternal vascular underperfusion (MVU) of the placental bed. On the premise that understanding the mechanisms of placental dysfunction could lead to targeted therapeutic options for human IUGR and PE, we investigated the roles of the placental UPR and oxidative stress in two rodent models of these human gestational path

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Alka and Kavita Dudhrejia. "An observational study of feto-maternal outcome in cases of abruptio placentae." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 8 (July 26, 2017): 3264. http://dx.doi.org/10.18203/2320-1770.ijrcog20173173.

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Background: Abruptio placentae defined as the preterm partial or complete separation of normally situated placenta from the uterine wall, complicating 1 in every 200 pregnancies (0.5-1%) in western nations, with rates as high as 4% in developing nations.Methods: This was a descriptive observational hospital-based study design with a follow-up component conducted over a period of 16 months, from January 2015 to April 2016 in the department of Obstetrics and Gynecology at RZH, PDU Medical College and hospital, Rajkot comprising of 83 cases.Results: A total of 83 cases of abruption placentae were

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Kuntal, Neha, Madhu Patni Bhat, Amit Nimawat, Munmun Yadav, and Mahendra Kumar Verma. "Feto-maternal outcomes following caesarean section: a prospective comparative study at tertiary care centre in North-Western Rajasthan." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 6 (May 26, 2018): 2311. http://dx.doi.org/10.18203/2320-1770.ijrcog20182341.

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Background: Caesarean section (CS) is employed when vaginal delivery is not feasible or hazardous to the mother and/or her baby. The procedure, however, is not without risk. We determined the fetomaternal outcomes of CS conducted at P.B.M Tertiary hospital situated in the North-Western region of Rajasthan.Methods: This is a Hospital based prospective comparative study of all CSs performed for various indications at the Dept. of Gynaecology and Obst., S.P. Medical College and P.B.M Hospital, Bikaner, India, from August 01, 2016, to July 31, 2017. All patients who had CS at any time within the 2

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Ayensu, Jessica, Reginald Adjetey Annan, Anthony Edusei, and Eric Badu. "Impact of maternal weight on pregnancy outcomes: a systematic review." Nutrition & Food Science 46, no. 4 (July 11, 2016): 542–56. http://dx.doi.org/10.1108/nfs-11-2015-0146.

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Purpose The nutritional status of a woman before and during pregnancy is important for a healthy pregnancy outcome. The increasing prevalence of maternal overweight and obesity worldwide has become a problem of concern among public health professionals. The purpose of this paper is to review the evidence regarding the impact of maternal weight on pregnancy outcomes to facilitate the provision of evidence-based information to pregnant women during antenatal clinics in Ghana. Design/methodology/approach A search was conducted in PubMed, PLOS ONE, Cochrane, Embase and bibliographies for all studi

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Vyalkova, A. A., B. A. Frolov, E. V. Savelyeva, and S. A. Chesnokova. "Prenatal stress and its role in children's pathology: historical aspects and the current status of the question (review of literature)." Nephrology (Saint-Petersburg) 24, no. 3 (April 23, 2020): 28–41. http://dx.doi.org/10.36485/1561-6274-2020-24-3-28-41.

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The article presents an analysis of fundamental data on the problem of stress and its role in the development of stressful diseases. Scientific evidence on the role of stress in childhood pathology indicates the extreme pathogenetic significance of stress. It is proved that stress has three interconnected faces: stress as a link in the adaptation mechanism, stress as a link in the pathogenesis of diseases and adaptation to stressful situations as a natural prevention of stressful diseases. The scientific substantiation of the main evolutionarily determined role of stress as an adaptation link

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Zhelezov, D. N., and O. M. Platonova. "Perinatal pregnancy outcomes with uterine scar." Ukrainian journal of Perinatology and Pediatrics, no. 1(85) (March 29, 2021): 11–16. http://dx.doi.org/10.15574/pp.2021.85.11.

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The increase in the frequency of surgical interventions on the uterus in women of fertile age caused increasing occurrence of pregnancies with one or more scars on the uterus. Purpose — to evaluate perinatal outcomes in women with a uterine scar. Materials and methods. The study involved 120 pregnant women who had a history of reconstructive surgery. The total sample was divided into the following clinical groups: I (n=70) — women who underwent conservative myomectomy, including 6 12 months before conception (group IA, n=30) and more than 1 year before conception (IB group, n=40); Group II (n=

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Kaminsky, Viacheslav, Tetiana Anoshina, and Tetiana Kolomiychenko. "Social and Medical Aspects of the Association HIV and Herpes Virus Infection in Pregnant Women." Family Medicine, no. 6 (December 30, 2016): 25–29. http://dx.doi.org/10.30841/2307-5112.6.2016.249003.

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The objective: to evaluate the social and health aspects of the association of HIV and herpes infections (GVI) in pregnant women. Patients and methods. Clinical and statistical analysis of 1177 individual cards of pregnant women with HIV for 5 years. The control group consisted of 200 pregnant women with physiological pregnancy. Results. Analysis of individual cards of pregnant women with HIV found insufficient to TORCH-infection survey (74,7%). The frequency of herpes infections in HIV-infected patients was 42,3%. The most common laboratory revealed HSV1/2 – 41,9%, CMV – 22,4% and

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Lumbala, Paul Kabuyi, Gloire Mbayabo, Mamy Nzita Ngole, Aimé Lumaka, Valerie Race, Gert Matthijs, Chris Van Geet, Prosper Tshilobo Lukusa, Koenraad Devriendt, and Tite Minga Mikobi. "Clinical and laboratory characterization of adult sickle cell anemia patients in Kinshasa." PLOS ONE 17, no. 12 (December 16, 2022): e0278478. http://dx.doi.org/10.1371/journal.pone.0278478.

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Background Sickle cell anemia (SCA) is a monogenic hemoglobinopathy associated with severe acute and chronic complications, with the highest incidence worldwide in Sub-Saharan Africa. The wide variability in clinical manifestations suggest that a uniform response to hydroxurea may not be attained. In view of a potential treatment with hydroxyurea (HU), we assessed the variability of clinical and hematological manifestations in a cohort of adults with SCA in Kinshasa, capital of the DR Congo in Central Africa. Methods A cross-sectional study was conducted in a hospital dedicated to SCA manageme

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Fiorentini, Elisa, Edda Russo, Amedeo Amedei, and Silvia Bellando Randone. "Fecal microbiome in systemic sclerosis, in search for the best candidate for microbiota-targeted therapy for small intestinal bacterial overgrowth control." Journal of Scleroderma and Related Disorders 7, no. 3 (September 25, 2022): 163–67. http://dx.doi.org/10.1177/23971983221118871.

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Gastrointestinal involvement is a common complication in systemic sclerosis patients and must be suspected and investigated already in the early stages of the disease. Gastrointestinal symptoms and complications—such as gastroesophageal reflux disease, intestinal pseudo-obstruction, malnutrition, diarrhea, constipation, and small intestinal bacterial overgrowth—severely impair systemic sclerosis patients’ quality of life and affect their prognosis. Although some pathogenetic aspects of the gastrointestinal involvement in systemic sclerosis remain unclear, defining the characteristics of the mi

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Nakanishi, Takehisa, Kento Mizutani, Shohei Iida, Yoshiaki Matsushima, Ai Umaoka, Makoto Kondo, Koji Habe, and Keiichi Yamanaka. "Janus Kinase Inhibitors Ameliorated Gastrointestinal Amyloidosis and Hypoalbuminemia in Persistent Dermatitis Mouse Model." International Journal of Molecular Sciences 23, no. 1 (December 21, 2021): 28. http://dx.doi.org/10.3390/ijms23010028.

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Malnutrition is not only regarded as a complication of rheumatoid arthritis and inflammatory bowel disease but also that of inflammatory skin disease; however, the mechanisms and efficacy of its treatment have not been elucidated. Using a mouse model of dermatitis, we investigated the pathophysiology of malnutrition in inflammatory skin conditions and efficacy of its treatment. We employed spontaneous skin inflammation mice models overexpressing human caspase-1 in the epidermal keratinocytes. Body weight, nutrition level, and α1-antitrypsin fecal concentration were measured. The gastrointestin

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Xie, Yan-Chun, Xu-Bin Jing, Xiang Chen, Ling-Zi Chen, Shao-Hui Zhang, and Xian-Bin Cai. "Fecal microbiota transplantation treatment for type 1 diabetes mellitus with malnutrition: a case report." Therapeutic Advances in Chronic Disease 13 (January 2022): 204062232211174. http://dx.doi.org/10.1177/20406223221117449.

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Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease. Not only genetics, but the intestinal environment affected by gut microbiota is also the key to pathogenesis. Besides the occurrence of diabetes, gut microbiota dysbiosis may also contribute to the development of diabetes-related complications. Fecal microbiota transplantation (FMT) is an emerging technique that had shown its potential as a treatment for metabolic disease. Here, we report the first case of T1DM with malnutrition and gastrointestinal symptoms treated with FMT. A 24-year-old T1DM patient suffered from poor blood gl

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Sibarani, Abraham Talent Bawadi, Hesti Triwahyu Hutami, Nani Maharani, and Yora Nindita. "Antidiarrheal Effect of Lime Peel Extract on Bisacodyl-Induced Mice." DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) 10, no. 6 (November 30, 2021): 438–44. http://dx.doi.org/10.14710/dmj.v10i6.32144.

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Background: Diarrhea is a condition of increased fecal water content of more than 200 grams or 200 ml/24 hours with a liquid or semi-liquid consistency. Complications of diarrhea, dehydration and malnutrition are still world health problems. Lime peel extract contains tannins which have astringent properties. Tannins are indicated as an alternative anti-diarrheal agent by tightening and forming a protective layer on the intestinal mucosa thereby reducing osmolarity.Aim: To examine the consistency, fecal water content, and frequency of defecation of bisacodyl-induced diarrhea in mice that are g

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Lesage, J., D. Hahn, M. Leonhardt, B. Blondeau, B. Breant, and JP Dupouy. "Maternal undernutrition during late gestation-induced intrauterine growth restriction in the rat is associated with impaired placental GLUT3 expression, but does not correlate with endogenous corticosterone levels." Journal of Endocrinology 174, no. 1 (July 1, 2002): 37–43. http://dx.doi.org/10.1677/joe.0.1740037.

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Fetal intrauterine growth restriction (IUGR) is a frequently occurring and serious complication of pregnancy. Infants exposed to IUGR are at risk for numerous perinatal morbidities, including hypoglycemia in the neonatal period, as well as increased risk of later physical and/or mental impairments, cardiovascular disease and non-insulin-dependent diabetes mellitus. Fetal growth restriction most often results from uteroplacental dysfunction during the later stage of pregnancy. As glucose, which is the most abundant nutrient crossing the placenta, fulfills a large portion of the fetal energy req

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Bhattacharya, Saptarshi, Lakshmi Nagendra, Aishwarya Krishnamurthy, Om J. Lakhani, Nitin Kapoor, Bharti Kalra, and Sanjay Kalra. "Early Gestational Diabetes Mellitus: Diagnostic Strategies and Clinical Implications." Medical Sciences 9, no. 4 (September 23, 2021): 59. http://dx.doi.org/10.3390/medsci9040059.

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Preexisting diabetes mellitus (DM) should be ruled out early in pregnancy in those at risk. During screening, a significant proportion of women do not reach the threshold for overt DM but fulfill the criteria used for diagnosing conventional gestational DM (cGDM). There is no consensus on the management of pregnancies with intermediate levels of hyperglycemia thus diagnosed. We have used the term early gestational DM (eGDM) for this condition and reviewed the currently available literature. Fasting plasma glucose (FPG), oral glucose tolerance test, and glycated hemoglobin (HbA1c) are the commo

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Minwuyelet, Awoke, Yibeltal Aschale, and Solomon Ayenew. "Extraintestinal Amoebiasis in Women after 6th Day of Delivery." Case Reports in Gastrointestinal Medicine 2021 (September 20, 2021): 1–4. http://dx.doi.org/10.1155/2021/1395404.

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Background. Extraintestinal amoebiasis is more common in countries with lower socioeconomic status. Complication related to amoebiasis is common in pregnant patients with malnutrition and others. Severe cases can be associated with high fatality rates. We would like to report a patient with a presumptive diagnosis of extraintestinal amoebiasis who was on the 6th postpartum day after intrauterine fetal death (IUFD). Case Presentation. The patient was a 31 year-old female who was on 6th postpartum day after IUFD after the 9th month of amenorrhea. She presented with severe epigastric pain, hiccup

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Ritivoiu, Mirela-Elena, Cristina Manuela Drăgoi, Dumitru Matei, Iustina Violeta Stan, Alina Crenguţa Nicolae, Mihai Craiu, Ion-Bogdan Dumitrescu, and Alina Angelica Ciolpan. "Current and Future Therapeutic Approaches of Exocrine Pancreatic Insufficiency in Children with Cystic Fibrosis in the Era of Personalized Medicine." Pharmaceutics 15, no. 1 (January 3, 2023): 162. http://dx.doi.org/10.3390/pharmaceutics15010162.

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This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of new therapies, such as cystic fibrosis transmembrane conductance regulator modulator therapies. Few articles evaluate the efficacy of pancreatic enzyme replacement therapy in the pediatric population, and most studies also included children and adults with cystic fibrosis. Approximately 85% of cystic fibrosis patients have exocrine pancreatic i

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Gramaglia, S. M. C., U. Cucinotta, V. Dipasquale, S. Arrigo, P. Gandullia, and C. Romano. "P263 Very early onset Inflammatory Bowel Diseases: Review of the Genoa-Messina joint clinical experience. Clinical history: Part I." Journal of Crohn's and Colitis 16, Supplement_1 (January 1, 2022): i304. http://dx.doi.org/10.1093/ecco-jcc/jjab232.390.

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Abstract Background Pediatric inflammatory bowel diseases (pIBD) have specific phenotypes compared to Inflammatory Bowel Diseases (IBD) in adults. The Very Early Onset-IBD (VEO-IBD) is considered a diagnosis of IBD in children before age 6 years old with 15% of prevalence. Methods The objective of this study was to compare the clinical and endoscopic features of VEO-IBD compared to pediatric IBD (diagnosis &gt; 6 years old) also in terms of natural history and response to treatment. The VEO patients followed at the IBD-Centers of Messina and Gaslini were enrolled retrospectively. We compar

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O’Higgins, Amy C., Anne Doolan, Laura Mullaney, Niamh Daly, Daniel McCartney, and Michael J. Turner. "The relationship between gestational weight gain and fetal growth: time to take stock?" Journal of Perinatal Medicine 42, no. 4 (January 1, 2014). http://dx.doi.org/10.1515/jpm-2013-0209.

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AbstractThe aim of this article is to review the current evidence on gestational weight gain (GWG). Maternal obesity has emerged as one of the great challenges in modern obstetrics as it is becoming increasingly common and is associated with increased maternal and fetal complications. There has been an upsurge of interest in GWG with an emphasis on the relationship between excessive GWG and increased fetal growth. Recent recommendations from the Institute of Medicine in the USA have revised downwards the weight gain recommendations in pregnancy for obese mothers. We believe that it is time to

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Snoek, Katinka M., Régine P. M. Steegers-Theunissen, Eric J. Hazebroek, Sten P. Willemsen, Sander Galjaard, Joop S. E. Laven, and Sam Schoenmakers. "The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis." Human Reproduction Update, August 13, 2021. http://dx.doi.org/10.1093/humupd/dmab022.

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Abstract BACKGROUND Worldwide, the prevalence of obesity in women of reproductive age is increasing. Bariatric surgery is currently viewed as the most effective, long-term solution for this problem. Preconception bariatric surgery can reduce the prevalence of obesity-related subfertility and adverse maternal, pregnancy and birth outcomes. Maternal health during the periconception period is crucial for optimal gametogenesis and for embryonic and fetal development which also affects health in the later lives of both mother and offspring. Although preconception bariatric surgery improves several

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Leung, Alexander K. C., Amy A. M. Leung, Alex H. C. Wong, and Kam L. Hon. "Human Ascariasis: An Updated Review." Recent Patents on Inflammation & Allergy Drug Discovery 14 (July 5, 2020). http://dx.doi.org/10.2174/1872213x14666200705235757.

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Background: Ascaris lumbricoides is the most common helminthic infection. More than 1.2 billion people have ascariasis worldwide. Objective: This article aimed to provide an update on the evaluation, diagnosis, and treatment of ascariasis. Methods: A PubMed search was conducted in February 2020 in Clinical Queries using the key terms “ascariasis” OR "Ascaris lumbricoides". The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews published within the past 10 years. The search was restricted to the English literature. The infor

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