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Tesi sul tema "Gastrointestinal system Motility"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 30 luglio 2024

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1

Andrews, Jane Mary. "Relationships between motor and sensory function in the proximal gut, appetite, & nutrients in healthy human subjects." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09pha567.pdf.

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Abstract (sommario):

Bibliography: leaves 206-251. The motor and sensory interactions between nutrients and proximal gut in humans are not well understood, despite the pivotal importance of these interactions on appetite, absorption and thus, nutrition. In part, this lack of knowledge results from technical difficulties in studying motor function in the human gut. In particular, the inability to continuously measure intraluminal flow with any degree of temporal resolution, has impeded progress in this field. The studies described in this thesis focus on nutrient-gut interactions, and also on the development of nov

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2

Spear, Estelle Trego. "Altered Gastrointestinal Motility in Multiple Sclerosis." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/837.

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Abstract (sommario):

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that causes motor, visual, and sensory symptoms. Patients also experience constipation, which is not yet understood, but could involve dysfunction of the enteric nervous system (ENS). Autoimmune targeting of the ENS occurs in other autoimmune diseases that exhibit gastrointestinal (GI) symptoms, and similar mechanisms could lead to GI dysfunction in MS. Here, we characterize GI dysmotility in the experimental autoimmune encephalomyelitis (EAE) model of MS and test whether autoantibodies targeting the ENS are present

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3

Jones, Karen Louise. "Studies of normal and disordered gastric motility in humans /." Title page, table of contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phj777.pdf.

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4

Boillat, Carol Simone. "Investigation of gastrointestinal motility in dogs using a wireless capsule system /." [S.l.] : [s.n.], 2009. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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5

HIRNING, LANE DURAND. "MULTIPLE PEPTIDE RECEPTORS AND SITES OF ACTION IN THE CANINE SMALL INTESTINE (OPIOIDS, MOTILIN, TACHYKININS, INTESTINAL MOTILITY, SUBSTANCE P)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/188150.

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Motility of the small intestine is a result of complex neurochemical and hormonal interactions within the intestine. The net motility (contraction) of the intestine is a balance of the influences from the central nervous system, enteric nervous system and hormonal changes in the body. Recently, the discovery of several peptide neurotransmitters common to the brain and the intestine has stimulated new research into the influence of these novel neurotransmitter candidates on intestinal motility at the level of the enteric (intestinal) nervous system. The present studies examined the contractile

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6

Lo, Wing-joe. "Effects of neurotransmitters and peptides on gastrointestinal motility in the shark, hemiscyllium plagiosum (Bennett) /." [Hong Kong : University of Hong Kong], 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13597322.

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7

羅穎祖 and Wing-joe Lo. "Effects of neurotransmitters and peptides on gastrointestinal motilityin the shark, hemiscyllium plagiosum (Bennett)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B3123382X.

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8

Zhao, Ling. "Increased bile acid-metabolizing bacteria contributes to enhanced gastrointestinal motility in irritable bowel syndrome." HKBU Institutional Repository, 2018. https://repository.hkbu.edu.hk/etd_oa/561.

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Abstract (sommario):

Irritable bowel syndrome (IBS), majorly characterized by irregular bowel movements and abdominal pain, is one of the most prevalent functional gastrointestinal disorders (FGIDs) in the world. Disturbance of gut microbiota, closely linking with gut dysfunction, has been regarded as one of important pathogenetic factors for IBS. However, gut microbiota-driven mechanism underlying IBS remains unclear, which leads to inefficient and non-specific effects of current microbiota-oriented therapy. In this thesis, function-based microbiota investigation with combination of metagenomic and metabolomic an

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9

Fone, David R. "Studies of the function of the human pylorus : and its role in the regulation of gastric emptying / David R. Fone." Title page, contents and summary only, 1990. http://web4.library.adelaide.edu.au/theses/09MD/09mdf673.pdf.

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10

Branstutter, Joseph W. "The role of nitric oxide in altering intestinal motility in lipopolysaccharide-injected rats : a morphological and functional assessment." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1136700.

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Nitric oxide, a short-lived free radical and neurotransmitter, is responsible for decreased smooth muscle contractility in vitro. When in excess, NO can cause hypotension and is believed to mediate altered intestinal motility. Not enough evidence is available for morphological changes in gastrointestinal smooth muscle and its correlation with motility disorders caused by Escherichia coli-induced NO production. Male Lewis rats were treated with injections of 10 mg/kg LPS from E. coli with or without 12.5 mg/kg of NOS inhibitor, LNMMA. Eighteen to 24 hours following injection, duodenum, ileum, c

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11

Jiang, Qi 1957. "Site of clonidine action to inhibit gut propulsion in mice: Demonstration of a central component." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/291819.

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The role of supraspinal, spinal and peripheral alpha-2 adrenoceptors in the regulation of gastrointestinal motility in mice was investigated using anatomically site specific administration of clonidine and adrenoceptor antagonists. Clonidine produced a dose-dependent inhibition of gastrointestinal transit when given by the i.c.v., i.th., or s.c. routes, and was most potent when given i.c.v. Yohimbine, an alpha-2 adrenoceptor antagonist, but not the alpha-1 antagonist prazosin, antagonized the antitransit effects of clonidine. Yohimbine was most potent in antagonizing i.c.v. clonidine; increase

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12

Flachsenberger, Wolfgang Arthur. "Studies on the peristaltic reflex /." Title page, contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phf571.pdf.

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13

Zhang, Man. "Modulatory effect of magnolol in colonic motility dysfunction induced by neonatal maternal separation in rats." HKBU Institutional Repository, 2010. http://repository.hkbu.edu.hk/etd_ra/1149.

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14

Treacy, Peter John. "Pyloric motor function in the control of gastric emptying /." Title page, contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09MD/09mdt784.pdf.

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15

Anvari, Mehran. "Mechanics of gastric emptying and the influence of gastric surgery /." Title page, contents and introduction only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09pha637.pdf.

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16

Huang, Tao. "Toward novel therapeutics for functional constipation: from traditional Chinese medicine herbal formula MaZiRenWan to cyclic spexin analogues." HKBU Institutional Repository, 2017. https://repository.hkbu.edu.hk/etd_oa/388.

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Abstract (sommario):

Functional constipation (FC) is a major gastrointestional (GI) disorder which affects about 14% population worldwide. However, due to efficacy and safety concerns, more than 50% FC patients are not completely satisfied with current conventional therapies, thus alternative therapies are needed. A substantial part of FC patients have symptom of slow colonic motility, while therapy targeting a single pathway cannot benefit all of them. In this thesis, we searched for novel FC therapeutics from two distinct sources, both of which can improve colonic motility significantly: (1) MaZiRenWan (MZRW), a

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17

Törnblom, Hans. "Pathogenetic mechanisms in irritable bowel syndrome /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-287-3/.

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18

Bobna, Aline Rosa Marosti. "Efeitos da isquemia/reperfusão intestinal sobre o receptor P2X2 e neurônios entéricos do íleo de ratos." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-15032012-163503/.

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A isquemia aguda mesentérica é uma condição de grande emergência vascular, que é fatal na população mundial em 60% a 80% dos casos. O objetivo desse trabalho foi estudar, os efeitos da isquemia/reperfusão intestinal sobre o receptor P2X2 e diferentes classes neuronais no plexo mioentérico. Foram analisados o íleo de ratos: controle, Sham e isquemia/reperfusão intestinal (I/R-i) com de 24h e 1 semana de reperfusão. Foram realizadas colocalização do receptor P2X2 com a NOS, ChAT, Calb, Calr, S100 e anti-HuC/D. Os resultados mostraram diminuição de neurônios P2X2-ir colocalizados com a NOS, ChAT

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19

May, Alexander T. "Identification of Expression and Function of the Glucagon-like Peptide-1 Receptor in Gastrointestinal Smooth Muscle." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4886.

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Abstract (sommario):

In response to ingestion of nutrients, enteroendocrine L cells secrete the incretin hormone, glucagon-like peptide-1 (GLP-1), to enhance glucose-dependent insulin release. Therapies related to GLP-1 are approved for type 2 diabetes. The GLP-1 receptor (GLP-1R) is expressed in cells of the gastrointestinal tract and elsewhere. In pancreatic beta cells, GLP-1R are coupled to the Gs/cAMP/PKA pathway. The expression and function of GLP-1R in gastrointestinal smooth muscle are not known. Aim. To test the hypothesis that GLP-1 regulates smooth muscle function by acting on GLP-1R expressed on smooth

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20

Marosti, Aline Rosa. "Análise morfoquantitativa e ultraestrutural dos componentes do plexo mioentérico do intestino delgado de ratos submetidos à dieta padrão de Moçambique nos períodos pré e pós-natal." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-08092016-095400/.

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Admite-se que mais de 40% das crianças são acometidas pela desnutrição crônica em Moçambique (África Oriental). A doença pode estar relacionada, entre outros fatores, à qualidade da dieta que é oferecida à população, já que é bastante precária, pois exibe sérias deficiências de ferro, gordura e, principalmente, proteína animal em sua composição. Essa insuficiência proteica poderia acarretar em prejuízo ao desenvolvimento do organismo, pois a proteína animal é considerada uma boa fonte de aminoácidos essenciais, em decorrência de sua maior digestibilidade e absorção no intestino delgado, quando

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21

Ngwainmbi, Joy. "Effects of HIV-1 Tat on the enteric nervous." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3752.

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More than 1.2 million people are estimated to be currently living with the human immunodeficiency virus (HIV) in the United States of America. The gastrointestinal (GI) tract is both a major target and an important component of HIV pathogenesis. The GI processes that are dysregulated during HIV infection are controlled by the enteric nervous system (ENS). Indeed, both clinical and experimental studies have implicated the ENS in HIV and simian immunodeficiency virus (SIV) pathogenesis. In addition to direct viral effects, the HIV virus also indirectly affects the GI tract via cellular and/or vi

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22

Palombit, Kelly. "Estudo do receptor P2X7 nas classes neuronais do íleo de ratos submetidos à isquemia intestinal com reperfusão." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42131/tde-05082010-103508/.

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Dor abdominal pode ser consequente a inúmeras causas, entre as várias possibilidades precisamos ficar atentos aos quadros de isquemia intestinal. No trato digestório a isquemia/reperfusão intestinal (I/R-i) acarreta alterações morfológicas nos neurônios entéricos. Este trabalho tem como objetivo analisar o comportamento das diferentes classes neuronais e do receptor P2X7 no plexo mioentérico do íleo de ratos Wistar submetidos à I/R-i. A isquemia intestinal foi obtida pela obstrução do fluxo sanguíneo das artérias ileais no período de 35 minutos, seguida pelos períodos de reperfusão de 6, 24, 7

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23

Elsenbruch, Sigrid. "Psychological and physiological responses to food intake and mental stress in the irritable bowel syndrome /." Oklahoma City : [s.n.], 1999. http://library.ouhsc.edu/epub/dissertations/Elsenbruch-Sigrid.pdf.

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24

MASTROPAOLO, Mariangela. "ANALISI DEI MECCANISMI DI CONTROLLO DELLA MOTILITA’ GASTROINTESTINALE DA PARTE DI ORMONI COINVOLTI NEL BILANCIO IDRICO-SALINO." Doctoral thesis, Università degli Studi di Palermo, 2014. http://hdl.handle.net/10447/91008.

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25

Blakeney, Bryan Adam. "Branched Short Chain Fatty Acid Isovaleric Acid Causes Smooth Muscle Relaxation via cAMP/PKA Pathway, Inhibits Gastrointestinal Motility, and Disrupts Peristaltic Movement." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5548.

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Isovaleric Acid (IVA) is a 5-carbon branched chain fatty acid present in fermented foods and produced by the fermentation of leucine by colonic bacteria. IVA activates G-protein coupled receptors such as FFAR2, FFAR3, and OR51E1 known to be expressed on enteric neurons and enteroendocrine cells. We previously reported that the shorter, straight chain fatty acids acetate, propionate and butyrate, differentially affect colonic propulsion; however, the effect of branched chain fatty acids on gastrointestinal motility is unknown. We hypothesize that IVA relaxes smooth muscle in a cAMP/PKA dependen

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26

Chaikomin, Reawika. "Gastrointestinal motility and glycaemic control in diabetes." 2006. http://hdl.handle.net/2440/37887.

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Gastric emptying, and small intestinal glucose exposure and absorption, are potentially important determinants of postprandial blood glucose homeostasis and energy intake. The studies presented in this thesis were designed to provide novel insights into the interrelationships of upper gastrointestinal function with glycaemia and appetite in both health and type 2 diabetes. The issues which were addressed relate in particular to : ( i ) the physiology, regulation and measurement of gastric and small intestinal motility, ( ii ) the relationships between small intestinal glucose exposure, increti

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27

Andrews, Jane M. "Relationships between motor and sensory function in the proximal gut, appetite, & nutrients in healthy human subjects / by Jane Mary Andrews." 1999. http://hdl.handle.net/2440/19606.

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Bibliography: leaves 206-251.<br>xii, 251 leaves : ill. ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>The motor and sensory interactions between nutrients and proximal gut in humans are not well understood, despite the pivotal importance of these interactions on appetite, absorption and thus, nutrition. In part, this lack of knowledge results from technical difficulties in studying motor function in the human gut. In particular, the inability to continuously measure intraluminal flow with any degree of tempora

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28

Rayner, Christopher Keith. "Regulation of upper gastrointestinal motility and sensation in health and disease / a thesis submitted by Christopher Keith Rayner." Thesis, 2000. http://hdl.handle.net/2440/19862.

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Includes bibliographical references (leaves 349-440).<br>440 leaves : ill. ; 30 cm.<br>The broad areas addressed are: the effect of physiological changes in the blood glucose concentration in the regulation of gastroduodenal motor and sensory function; the effect of acute hyperglycaemia on gastric motor and sensory function in patients with diabetes mellitus and the motor response to prokinetic therapy; the relationships between small intestinal nutrient exposure, gastrointestinal peptide hormone release, antropyloric motility and appetite; and, the effect of aging on the proximal gastric resp

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29

Rayner, Christopher Keith. "Regulation of upper gastrointestinal motility and sensation in health and disease / a thesis submitted by Christopher Keith Rayner." 2000. http://hdl.handle.net/2440/19862.

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Includes bibliographical references (leaves 349-440).<br>440 leaves : ill. ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>The broad areas addressed are: the effect of physiological changes in the blood glucose concentration in the regulation of gastroduodenal motor and sensory function; the effect of acute hyperglycaemia on gastric motor and sensory function in patients with diabetes mellitus and the motor response to prokinetic therapy; the relationships between small intestinal nutrient exposure, gastrointest

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30

Chapman, Marianne. "Gastro-duodenal motility & nutrition in the critically ill." Thesis, 2008. http://hdl.handle.net/2440/50961.

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Inadequate delivery of nutrition to the critically ill is common, and may adversely affect clinical outcomes, including survival. This thesis reports studies designed to characterise the gastrointestinal dysfunction underlying feed intolerance in the critically ill, as well as the pathophysiology of these dysfunctions, and investigate potential therapeutic measures. While it has been established that enteral nutrition is frequently unsuccessful in the critically ill, assessment of the success of feeding in an Australian intensive care unit (ICU) had not been performed previously. A prospecti

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31

Chapman, Marianne. "Gastro-duodenal motility & nutrition in the critically ill." 2008. http://hdl.handle.net/2440/50961.

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Inadequate delivery of nutrition to the critically ill is common, and may adversely affect clinical outcomes, including survival. This thesis reports studies designed to characterise the gastrointestinal dysfunction underlying feed intolerance in the critically ill, as well as the pathophysiology of these dysfunctions, and investigate potential therapeutic measures. While it has been established that enteral nutrition is frequently unsuccessful in the critically ill, assessment of the success of feeding in an Australian intensive care unit (ICU) had not been performed previously. A prospective

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32

Fraser, Robert J. L. "Relationship between gastric emptying and organisation of antropyloroduodenal pressure waves / R.J.L. Fraser." 1992. http://hdl.handle.net/2440/20556.

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Bibliography: leaves 258-294.<br>xv, 294 leaves : ill. (1 col.) ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Examines the organisation and control of the antropyloroduodenal motor unit in both healthy human volunteers and patients with gastroparesis.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1992

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33

Maddern, Guy John. "Upper gastro-intestinal motility and gastro-oesophageal reflux." Thesis, 1985. http://hdl.handle.net/2440/115120.

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34

Kwiatek, Monika Agnieszka. "Transpyloric flow and associated motility in health and following pharmacologic modulation." 2006. http://arrow.unisa.edu.au:8081/1959.8/46310.

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Transpyloric flow is the final step in gastric emptying prior to intestinal absorption of nutrients and medications. The details of this process are still incompletely understood. Transpyloric flow is bi-directional, contrasting with the general perception of solely forward flow implied by studies of gross gastric emptying. The degree to which the patterns of bi-directional transpyloric flow reflect emptying of meals of varied physicochemical composition, its mechanical determinants and effect on delivery of oral medications have been evaluated by the studies presented in this thesis.

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35

"Studies on the absorption of Schisandra chinensis and its pharmacological effects on gut motility and visceral sensation." Thesis, 2009. http://library.cuhk.edu.hk/record=b6075318.

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In an irritable bowel syndrome (IBS) rat model, S. chinensis reversed the exaggerated visceral nocicptive responses (judged by abdominal withdrawal reflex and electromyographic measurement) to colorectal distension induced by neonatal maternal separation. Relief of visceral hypersensitivity by S. chinensis could be related to the decrease of elevated 5-HT level and the reduction in 5-HT3 receptor expression in colon.<br>In summary, given the modulatory effects on intestinal motility and visceral sensation, Schisandra chinensis would be potentially useful for the treatment of relieving diarrhe

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36

Flachsenberger, Wolfgang Arthur. "Studies on the peristaltic reflex / by Wolfgang Arthur Flachsenberger." Thesis, 1985. http://hdl.handle.net/2440/20368.

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37

"An investigation into gastric myoelectrical activity in response to drug treatment during ageing and in a mouse model of Alzheimer's disease." 2013. http://library.cuhk.edu.hk/record=b5884352.

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Wang, Hui Chuan.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 184-202).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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38

Bartlett, Ellis Rebecca J. "In vitro comparison of gastric aspirate methods and feeding tube properties on the quantity and reliability of obtained aspirate volume." Thesis, 2013. http://hdl.handle.net/1805/3690.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Gastric residual volume (GRV) is a clinical assessment to evaluate gastric emptying and enteral feeding tolerance. Factors such as the tube size, tube material, tube port configuration, placement of the tube in the gastric fluid, the amount of fluid and person completing the assessment may influence the accuracy of residual volume assessment. Little attention has been paid to assessing the accuracy of GRV measurement when the actual volume being aspirated is known, and no studies have compared the accuracy in obtaining RV using the t

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