Letteratura scientifica selezionata sul tema "Gene Expression RNA, Messenger"

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Articoli di riviste sul tema "Gene Expression RNA, Messenger"

1

Bøe, Sigurd, Stein Sæbøe-Larssen, and Eivind Hovig. "Light-Induced Gene Expression Using Messenger RNA Molecules." Oligonucleotides 20, no. 1 (2010): 1–6. http://dx.doi.org/10.1089/oli.2009.0209.

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Frye, Michaela, Bryan T. Harada, Mikaela Behm, and Chuan He. "RNA modifications modulate gene expression during development." Science 361, no. 6409 (2018): 1346–49. http://dx.doi.org/10.1126/science.aau1646.

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Abstract (sommario):
RNA modifications have recently emerged as critical posttranscriptional regulators of gene expression programs. They affect diverse eukaryotic biological processes, and the correct deposition of many of these modifications is required for normal development. Messenger RNA (mRNA) modifications regulate various aspects of mRNA metabolism. For example,N6-methyladenosine (m6A) affects the translation and stability of the modified transcripts, thus providing a mechanism to coordinate the regulation of groups of transcripts during cell state maintenance and transition. Similarly, some modifications
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Zhang, Jing, Fanghui Ding, Dan Jiao, Qiaozhi Li, and Hong Ma. "The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance." Technology in Cancer Research & Treatment 19 (January 1, 2020): 153303382091733. http://dx.doi.org/10.1177/1533033820917332.

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RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients with various types of cancer. Although gastric cancer is a relatively frequent and potentially fatal malignancy, the mechanism by which insulin-like growth factor 2 messenger RNA–binding protein 3 regulates the development of this cancer remains unclear. This study aimed to investigate the role and regulatory mechanism of insulin-like growth facto
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4

Weil, D., S. Brosset, and F. Dautry. "RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2." Molecular and Cellular Biology 10, no. 11 (1990): 5865–75. http://dx.doi.org/10.1128/mcb.10.11.5865.

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We have previously reported that tumor necrosis factor beta (TNF beta) expression is induced by interleukin-2 (IL-2) in the murine lymphocytic T-cell line CTLL-2. In this study, we have characterized the nuclear and cytoplasmic TNF beta transcript and assessed their role in TNF beta gene expression. A unique feature of TNF beta expression was the accumulation of nuclear precursors, which reflected a slow nuclear RNA processing. As a consequence, there was a delay in the appearance of cytoplasmic messengers after the transcriptional induction of TNF beta by IL-2. We also found that two messenge
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Weil, D., S. Brosset, and F. Dautry. "RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2." Molecular and Cellular Biology 10, no. 11 (1990): 5865–75. http://dx.doi.org/10.1128/mcb.10.11.5865-5875.1990.

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We have previously reported that tumor necrosis factor beta (TNF beta) expression is induced by interleukin-2 (IL-2) in the murine lymphocytic T-cell line CTLL-2. In this study, we have characterized the nuclear and cytoplasmic TNF beta transcript and assessed their role in TNF beta gene expression. A unique feature of TNF beta expression was the accumulation of nuclear precursors, which reflected a slow nuclear RNA processing. As a consequence, there was a delay in the appearance of cytoplasmic messengers after the transcriptional induction of TNF beta by IL-2. We also found that two messenge
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6

Lei, Sibei, Xueyan Zhang, Jingmei Li, et al. "Current Progress in Messenger RNA-Based Gene Therapy." Journal of Biomedical Nanotechnology 16, no. 7 (2020): 1018–44. http://dx.doi.org/10.1166/jbn.2020.2961.

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Based on its rapid expression, simple sequence composition, low immunogenicity, and flexible modification possibilities, in vitro synthesized mRNA has demonstrated strong potential as a candidate for gene therapy. Many efforts have been made to enhance its therapeutic efficacy and safety. Profiting from the development in pathogenesis and materials science, much progress has been achieved in mRNA-based therapy studies. Many mRNA-derived therapeutics including vaccines, antibodies, cytokines, and growth factors have emerged for the treatment of diverse diseases that have multiple modes of actio
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Fioravanti, Antonella, Luigi Pirtoli, Antonio Giordano, and Francesco Dotta. "Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology." International Journal of Molecular Sciences 21, no. 4 (2020): 1270. http://dx.doi.org/10.3390/ijms21041270.

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Barrow, L., M. S. Tanner, and D. R. Critchley. "Expression of the Caeruloplasmin Gene in the Adult and Neonatal Rat Liver." Clinical Science 77, no. 3 (1989): 259–63. http://dx.doi.org/10.1042/cs0770259.

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1. It has been suggested that low levels of serum caeruloplasmin in Wilson's disease result from the failure to switch from a fetal to an adult mode of caeruloplasmin gene expression. To investigate postnatal expression of the caeruloplasmin gene, steady-state levels of caeruloplasmin messenger RNA in adult and neonatal rat liver were measured. 2. Copper parameters observed in neonatal rats were similar to those seen in Wilson's disease: hepatic copper concentration was significantly elevated (neonatal 164 ± 35 μg/g, adults 50 ± 8 μg/g, P < .001) and serum copper and caeruloplasmin levels w
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Carrier, T. A., and J. D. Keasling. "Controlling Messenger RNA Stability in Bacteria: Strategies for Engineering Gene Expression." Biotechnology Progress 13, no. 6 (1997): 699–708. http://dx.doi.org/10.1021/bp970095h.

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Straub, Bernd, Markus Müller, Hans Krause, Mark Schrader, Carsten Goessl, and Kurt Miller. "Receptor Gene Messenger RNA Expression in Metastatic Lesions of Prostate Cancer." Journal of Urology 168, no. 3 (2002): 1212–14. http://dx.doi.org/10.1016/s0022-5347(05)64627-7.

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Tesi sul tema "Gene Expression RNA, Messenger"

1

Taylor, David C. "SELEX targeting mRNAs : the hunt for novel riboregulators /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3013032.

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Brown, Justin Travis. "MRNA degradation in the control of gene expression in yeast." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3024999.

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Turk, Casey M. "Paralemmin splice variants and mRNA and protein expression in breast cancers." Connect to this title, 2008. http://scholarworks.umass.edu/theses/194/.

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Loushin, Newman Carrie Lee. "Characterization of QKI RNA binding function /." Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004323.

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Jenh, Chung-Her. "Thymidylate synthase gene amplification and messenger RNA expression in fluorodeoxyuridine-resistant mouse cells /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261919111867.

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Soop, Teresa. "Assembly and transport of messenger and ribosomal RNP particles in the dipteran Chironomus tentans /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-521-2/.

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Forrest, Megan E. "Regulation of Mammalian Messenger RNA Stability via the Open Reading Frame." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1579862741902687.

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Howe, Whitney M. "The mechanism of gene expression regulation by the ykkCD putative riboswitch." Muncie, Ind. : Ball State University, 2009. http://cardinalscholar.bsu.edu/652.

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Almasoudi, Kholoud S. "The fate of nonsense-mediated RNA decay factors and their substrates during neuronal differentiation." Thesis, University of Aberdeen, 2018. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=238313.

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Marshall, Elizabeth. "Mathematical modelling of the effect of ribosome recycling on messenger RNA translation and degradation in Saccharomyces cerevisiae." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=216334.

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Abstract (sommario):
I present the results of my analysis of the final stage of gene expression, the translation of messenger RNA. Translation is carried out by large molecular motors called ribosomes, which move along the mRNA molecule in a stepwise fashion, producing a polypeptide chain. Translation can be modelled as a driven diffusion process, and I extend the Totally Asymmetric Simple Exclusion Process (TASEP) to consider the possibility that ribosomes that terminate from the lattice can rejoin the lattice to reinitiate translation, known as ribosome recycling. Inclusion of recycling leads to marked changes i
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Libri sul tema "Gene Expression RNA, Messenger"

1

F, Gesteland Raymond, and SpringerLink (Online service), eds. Recoding: Expansion of Decoding Rules Enriches Gene Expression. Springer Science+Business Media, LLC, 2010.

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2

Riboswitches: Methods and protocols. Humana, 2009.

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3

Maxim, Golovkin, and SpringerLink (Online service), eds. Nuclear pre-mRNA Processing in Plants. Springer-Verlag Berlin Heidelberg, 2008.

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4

EMBO/INSERM Workshop on Regulation of Gene Expression by RNA Structure and Anti-messengers (1988 Les Arcs,Savoie). Papers presented atthe EMBO/INSERM Workshop on Regulation of Gene Expression by RNA Structure and Anti-messengers, Les Arcs, Savoie (France), 28 february-4 March 1988. Elsevier Science, 1988.

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Clouet-d'Orval, Béatrice, ed. RNA Metabolism and Gene Expression in Archaea. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-65795-0.

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Koloteva, Nadejda. Regulation of eukaryotic gene expression via RNA-RNA and RNA-protein interactions. UMIST, 1997.

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Wang, Zhiguo. MicroRNA expression detection methods. Springer, 2010.

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8

J, Kay, Ballard F. J, and Mayer R. J, eds. Gene expression: Regulation at the RNA and protein levels. Biochemical Society, 1989.

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9

NATO/CEC, Advanced Research Workshop on "Post-Transcriptional Control of Gene Expression" (1990 Goslar Germany). Post-transcriptional control of gene expression. Springer-Verlag, 1990.

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10

Next-generation MicroRNA expression profiling technology: Methods and protocols. Humana Press, 2012.

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Capitoli di libri sul tema "Gene Expression RNA, Messenger"

1

Theil, Elizabeth C. "Storage and Translation of Ferritin Messenger RNA." In Translational Regulation of Gene Expression. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5365-2_7.

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2

Subramanian, A. R. "Ribosomal Protein S1: “The Messenger RNA-Catching Arm” of Escherichia Coli Ribosome." In Gene Manipulation and Expression. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-6565-5_28.

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Fladung, Matthias, Hely Häggman, and Suvi Sutela. "Application of RNAi technology in forest trees." In RNAi for plant improvement and protection. CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0054.

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Abstract A diverse set of small RNAs is involved in the regulation of genome organization and gene expression in plants. These regulatory sRNAs play a central role for RNA in evolution and ontogeny in complex organisms, including forest tree species, providers of indispensable ecosystem services. RNA interference is a process that inhibits gene expression by double-stranded RNA and thus causes the degradation of target messenger RNA molecules. Targeted gene silencing by RNAi has been utilized in various crop plants in order to enhance their characteristics. For forest tree species, most of the successful RNAi modification has been conducted in poplar. Over the past 20 years, successful RNAi-mediated suppression of gene expression has been achieved with a variety of economically important traits. Moreover, the stability of RNAi-mediated transgene suppression has been confirmed in field-grown poplars. In this chapter, we describe examples of successful RNAi applications mainly in poplar but also provide some information about application of RNAi in pest control in forest tree species. Advantages and disadvantages of this technology with respect to the particular features of forest tree species will be discussed.
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Fladung, Matthias, Hely Häggman, and Suvi Sutela. "Application of RNAi technology in forest trees." In RNAi for plant improvement and protection. CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0007.

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Abstract (sommario):
Abstract A diverse set of small RNAs is involved in the regulation of genome organization and gene expression in plants. These regulatory sRNAs play a central role for RNA in evolution and ontogeny in complex organisms, including forest tree species, providers of indispensable ecosystem services. RNA interference is a process that inhibits gene expression by double-stranded RNA and thus causes the degradation of target messenger RNA molecules. Targeted gene silencing by RNAi has been utilized in various crop plants in order to enhance their characteristics. For forest tree species, most of the successful RNAi modification has been conducted in poplar. Over the past 20 years, successful RNAi-mediated suppression of gene expression has been achieved with a variety of economically important traits. Moreover, the stability of RNAi-mediated transgene suppression has been confirmed in field-grown poplars. In this chapter, we describe examples of successful RNAi applications mainly in poplar but also provide some information about application of RNAi in pest control in forest tree species. Advantages and disadvantages of this technology with respect to the particular features of forest tree species will be discussed.
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5

Gehrke, Lee, and Stephen A. Jobling. "Untranslated Leader Sequences and Enhanced Messenger RNA Translational Efficiency." In Post-Transcriptional Control of Gene Expression. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75139-4_36.

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Laz, Thomas, John Clements, and Fred Sherman. "The Role of Messenger RNA Sequences and Structures in Eukaryotic Translation." In Translational Regulation of Gene Expression. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5365-2_19.

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Rosenthal, Eric, and Fred Wilt. "Selective Messenger RNA Translation in Marine Invertebrate Oocytes, Eggs, and Zygotes." In Translational Regulation of Gene Expression. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5365-2_5.

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Edery, Isaac, Jerry Pelletier, and Nahum Sonenberg. "Role of Eukaryotic Messenger RNA Cap-Binding Protein in Regulation of Translation." In Translational Regulation of Gene Expression. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5365-2_15.

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Gehrke, Lee. "Differential Translation of Eukaryotic Messenger RNAs." In Translational Regulation of Gene Expression. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5365-2_16.

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Platt, T., C. A. Brennan, J. S. Butler, et al. "Messenger RNA 3′ End Formation in E. Coli and S. Cerevisiae." In Post-Transcriptional Control of Gene Expression. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75139-4_14.

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Atti di convegni sul tema "Gene Expression RNA, Messenger"

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Verdugo, Anael, and Richard H. Rand. "Delay Differential Equations in the Dynamics of Gene Copying." In ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/detc2007-34214.

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We analyze a model of gene transcription and protein synthesis which has been previously presented in the biological literature. The model takes the form of an ODE (ordinary differential equation) coupled to a DDE (delay differential equation), the state variables being concentrations of messenger RNA and protein. The delay is assumed to depend on the concentration of mRNA and is therefore state-dependent. Linear analysis gives a critical time delay beyond which a periodic motion is born in a Hopf bifurcation. Lindstedt’s method is applied to the nonlinear system, resulting in closed form appr
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Wu, Q. Y., B. R. Bahnak, L. Coulombel, J. P. Caen, G. Pietu, and D. Meyer. "VON WILLEBRAND FACTOR mRNA IS SEVERELY REDUCED IN PIGS WITH HOMOZYGOUS VON WILLEBRAND DISEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644113.

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Porcine von Willebrand disease (vWD), an autosomal recessive disorder, is similar to some of the severe forms of vWD in humans and is characterized by a prolonged bleeding time and very low or undetectable amounts of von Willebrand factor (vWF) antigen and activity in plasma, platelets and endothelial cells. The molecular events that control the lack of expression of vWF in the vWD pigs is not known and could be at the transcriptional or post-transcriptional level. Lungs from normal and two homozygous vWD pigs were extracted immediately after harvesting of the animals and placed on dry ice. Ti
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Liu, Xian Shuang, Baoyan Fan, Xinli Wang, Michael Chopp, and Zheng Gang Zhang. "Differential long noncoding RNA and messenger RNA expression profiling and functional network analysis in stroke-induced neurogenesis." In 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2019. http://dx.doi.org/10.1109/bibm47256.2019.8983210.

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Migneault, Francis, Andre Dagenais, and Yves Berthiaume. "Cycloheximide And Lipopolysaccharides (LPS): Inhibitors Of Epithelial Sodium Channel (±-ENaC) Messenger RNA Expression." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3517.

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Harati, Sahar, John H. Phan, and May D. Wang. "Investigation of factors affecting RNA-seq gene expression calls." In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2014. http://dx.doi.org/10.1109/embc.2014.6944805.

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Wang, Tianyu, and Sheida Nabavi. "Differential gene expression analysis in single-cell RNA sequencing data." In 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2017. http://dx.doi.org/10.1109/bibm.2017.8217650.

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He, Mu-yang, Hao-jie Cao, Le Wang, and Shou-jing Zhao. "Construction of Ginseng CS Gene RNA Interference Plant Expression Vector." In 2012 International Conference on Biomedical Engineering and Biotechnology (iCBEB). IEEE, 2012. http://dx.doi.org/10.1109/icbeb.2012.115.

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Po-Yen Wu, J. H. Phan, Fengfeng Zhou, and M. D. Wang. "Evaluation of normalization methods for RNA-Seq gene expression estimation." In 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW). IEEE, 2011. http://dx.doi.org/10.1109/bibmw.2011.6112354.

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Ei-Wen Yang, Thomas Girkes, and Tao Jaing. "Differential gene expression analysis using coexpression and RNA-Seq data." In 2013 IEEE 3rd International Conference on Computational Advances in Bio and Medical Sciences (ICCABS). IEEE, 2013. http://dx.doi.org/10.1109/iccabs.2013.6629222.

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Yang, Cheng, Po-Yen Wu, Li Tong, John Phan, and May Wang. "The impact of RNA-seq aligners on gene expression estimation." In BCB '15: ACM International Conference on Bioinformatics, Computational Biology and Biomedicine. ACM, 2015. http://dx.doi.org/10.1145/2808719.2808767.

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Rapporti di organizzazioni sul tema "Gene Expression RNA, Messenger"

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Ljungman, Mats. Use of Nascent RNA Microarrays to Study Inducible Gene Expression in Breast Cancer Cells. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443027.

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Vang, Lindsay K., P. Scott Pine, Sarah A. Munro, and Marc L. Salit. Preparation of a set of total RNA benchmarking samples for performance assessment of genome-scale differential gene expression. National Institute of Standards and Technology, 2017. http://dx.doi.org/10.6028/nist.sp.1200-23.

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