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Articoli di riviste sul tema "Immunoglobulins"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

Markina, Yuliya V., Elena V. Gerasimova, Alexander M. Markin, et al. "Sialylated Immunoglobulins for the Treatment of Immuno-Inflammatory Diseases." International Journal of Molecular Sciences 21, no. 15 (2020): 5472. http://dx.doi.org/10.3390/ijms21155472.

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Immunoglobulins are the potent effector proteins of the humoral immune response. In the course of evolution, immunoglobulins have formed extremely diverse types of molecular structures with antigen-recognizing, antigen-binding, and effector functions embedded in a single molecule. Polysaccharide moiety of immunoglobulins plays the essential role in immunoglobulin functioning. There is growing evidence that the carbohydrate composition of immunoglobulin-linked glycans, and especially their terminal sialic acid residues, provide a key effect on the effector functions of immunoglobulins. Possibly

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2

Okamoto, Yasuyuki, Noboru Hamada, Toshimichi Fujisawa, et al. "Why no simple relationship between thyroid peroxidase activity-inhibiting immunoglobulins and thyroid function in autoimmune thyroid disease?" Acta Endocrinologica 124, no. 4 (1991): 442–48. http://dx.doi.org/10.1530/acta.0.1240442.

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Abstract. We have reported that some anti-thyroid peroxidase antibodies inhibit the activity of thyroid peroxidase in vitro. These thyroid peroxidase activity-inhibiting immunoglobulins seem to inhibit thyroid function in some patients, but the relationship between thyroid peroxidase activity-inhibiting immunoglobulins and thyroid function is not simple. We designed this study to explore this lack of a simple relationship. We stained immunoglobulin G deposits by immunofluorescence staining or the peroxidase-antiperoxidase method, and stained endogenous thyroid peroxidase activity by enzyme his

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3

Almaghlouth, Ibrahim, Sindhu R. Johnson, Eleanor Pullenayegum, Dafna Gladman, and Murray Urowitz. "Immunoglobulin levels in systemic lupus erythematosus: A narrative review." Lupus 30, no. 6 (2021): 867–75. http://dx.doi.org/10.1177/09612033211004714.

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Immunoglobulins play a fundamental role in the protection of the human body against internal and external threats. They also contribute to the immune system homeostasis and maintenance of self-tolerance. Hypogammaglobulinemia is occasionally encountered in routine clinical practice by rheumatologists. Low levels of immunoglobulins can occur as primary or secondary issues and may predispose patients to various forms of infection. However, the impact of the low immunoglobulin level abnormality varies with the underlying condition. In this narrative review, we shed light on the overall types and

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4

DREW, M. D., and B. D. OWEN. "THE PROVISION OF PASSIVE IMMUNITY TO COLOSTRUM-DEPRIVED PIGLETS BY BOVINE OR PORCINE SERUM IMMUNOGLOBULINS." Canadian Journal of Animal Science 68, no. 4 (1988): 1277–84. http://dx.doi.org/10.4141/cjas88-143.

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Bovine and porcine serum immunoglobulins were obtained from abattoir blood by sodium polyphosphate fractionation and mixed with sow milk replacer to provide an IgG level of 20 mg mL−1 for diets fed on day 1 and 4 mg mL−1 for diets fed on days 2–14. Control piglets received only sow milk replacer. The control group had a survival rate of 22% compared to 75% for the piglets receiving bovine immunoglobulins and 92% for those receiving porcine immunoglobulins. Diarrhea was more severe in the control group for the first 21 d than in the other two groups. The bovine and porcine groups did not differ

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5

Goode, N. P., A. M. Davison, G. Gowland, and M. Shires. "Spontaneous glomerular immunoglobulin deposition in young Sprague-Dawley rats." Laboratory Animals 22, no. 4 (1988): 287–92. http://dx.doi.org/10.1258/002367788780746232.

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The frequency, age-onset and distribution of spontaneously deposited immunoglobulins (lgs) in glomeruli of Sprague-Dawley rats has been investigated. Groups of rats ( n=10) were examined at 4-7 day intervals from birth (presuckling) until 30 days of age. Findings were compared with circulating immunoglobulin concentrations in each age group. Immunoglobulins were undetectable in immature kidneys of newborn rats. However, as early as 5 days, scanty IgA and IgM deposits were observed predominantly in mesangial areas of mature glomeruli, corresponding to low circulating concentrations of these imm

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6

Srikumaran, S., E. A. Kluever, D. V. Onisk, and K. Hariharan. "Quantitation of bovine immunoglobulins in culture fluids by use of sandwich radioimmunoassay with monoclonal antibodies." American Journal of Veterinary Research 52, no. 2 (1991): 243–46. http://dx.doi.org/10.2460/ajvr.1991.52.02.243.

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SUMMARY Bovine immunoglobulin isotype-specific murine monoclonal antibodies were used in sandwich radioimmunoassays to detect and quantitate bovine IgG1, IgG2, IgM, and IgA in culture fluids. The concentrations of bovine immunoglobulins in unknown samples were extrapolated from standard curves generated with bovine monoclonal immunoglobulins. The lowest detection limits for the bovine immunoglobulin isotypes ranged from 65 to 270 ng/ml.

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7

Westhrin, Marita, Vlado Kovcic, Zejian Zhang, et al. "Monoclonal immunoglobulins promote bone loss in multiple myeloma." Blood 136, no. 23 (2020): 2656–66. http://dx.doi.org/10.1182/blood.2020006045.

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Abstract Most patients with multiple myeloma develop a severe osteolytic bone disease. The myeloma cells secrete immunoglobulins, and the presence of monoclonal immunoglobulins in the patient’s sera is an important diagnostic criterion. Here, we show that immunoglobulins isolated from myeloma patients with bone disease promote osteoclast differentiation when added to human preosteoclasts in vitro, whereas immunoglobulins from patients without bone disease do not. This effect was primarily mediated by immune complexes or aggregates. The function and aggregation behavior of immunoglobulins are p

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8

Gong, Yuxin, Bo Liao, Dejun Peng, and Quan Zou. "Accurate Prediction and Key Feature Recognition of Immunoglobulin." Applied Sciences 11, no. 15 (2021): 6894. http://dx.doi.org/10.3390/app11156894.

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Immunoglobulin, which is also called an antibody, is a type of serum protein produced by B cells that can specifically bind to the corresponding antigen. Immunoglobulin is closely related to many diseases and plays a key role in medical and biological circles. Therefore, the use of effective methods to improve the accuracy of immunoglobulin classification is of great significance for disease research. In this paper, the CC–PSSM and monoTriKGap methods were selected to extract the immunoglobulin features, MRMD1.0 and MRMD2.0 were used to reduce the feature dimension, and the effect of discrimin

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9

Hasegawa, Haruki. "Aggregates, Crystals, Gels, and Amyloids: Intracellular and Extracellular Phenotypes at the Crossroads of Immunoglobulin Physicochemical Property and Cell Physiology." International Journal of Cell Biology 2013 (2013): 1–22. http://dx.doi.org/10.1155/2013/604867.

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Recombinant immunoglobulins comprise an important class of human therapeutics. Although specific immunoglobulins can be purposefully raised against desired antigen targets by various methods, identifying an immunoglobulin clone that simultaneously possesses potent therapeutic activities and desirable manufacturing-related attributes often turns out to be challenging. The variable domains of individual immunoglobulins primarily define the unique antigen specificities and binding affinities inherent to each clone. The primary sequence of the variable domains also specifies the unique physicochem

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10

Спицын, А. Н., Д. В. Уткин, М. Н. Киреев та ін. "Спектрофотометрическая характеристика конъюгатов иммуноглобулинов для диагностики возбудителей особо опасных инфекций". Журнал технической физики 128, № 3 (2020): 430. http://dx.doi.org/10.21883/os.2020.03.49071.76-19.

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The possibility of using spectrophotometric analysis to characterize fluorescent immunoglobulins as a control method was considered. A comparative analysis of the optical properties of fluorescent immunoglobulin preparations and their constituent components - immunoglobulins, fluorochrome was carried out. The results suggest that the proposed methodological approach of optical detection of labeled immunoglobulin molecules is promising for controlling the preparation of conjugates used in the formulation of immunological reactions to identify specific antigens of pathogens of particularly dange

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11

Shehzad, Muzzamil, Tayyab Ali, Nusrat Bibi, and Shoaib Shafique. "A comprehensive review on preparation of pure immunoglobulins Authors." International Journal of Natural Medicine and Health Sciences 2, no. 1 (2022): 48–55. http://dx.doi.org/10.52461/ijnms.v2i1.1372.

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Immunoglobulins are also known as antibodies. Plasma cells are responsible for the production of immunoglobulins. Beta cells are activated against a pathogenic attack and facilitated the formation of different types of immunoglobulins naturally. These immunoglobulins are also artificially synthesized by non-specific laboratorial techniques include fractionation precipitation, electrophoretic methods, gel filtration chromatography, ion exchange chromatography, hydrophobic chromatography and by the specific immuno- adsorbent methods. Third generation immunoglobulins are effectively used for ther

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12

Lock, R. J., and D. J. Unsworth. "Immunoglobulins and immunoglobulin subclasses in the elderly." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 40, no. 2 (2003): 143–48. http://dx.doi.org/10.1258/000456303763046067.

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Background: Published data imply that adult concentrations are achieved for all Ig isotypes and plateau by 15--18 years of age. Recent data, however, suggest that these results are not applicable in the elderly. There are no equivalent data for IgG subclasses. We present reference range data for an elderly UK patient population, for IgG, IgA, IgM and IgG subclasses. Methods: Serum immunoglobulins were reviewed on samples from 1146 patients > 60 years of age and 925 patients aged 18--60 years. Serum IgG subclasses were reviewed on samples from 498 patients >60 years and 484 patients aged

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13

Walther, Stefanie, Tamara V. Rusitzka, Ulrike S. Diesterbeck, and Claus-Peter Czerny. "Equine immunoglobulins and organization of immunoglobulin genes." Developmental & Comparative Immunology 53, no. 2 (2015): 303–19. http://dx.doi.org/10.1016/j.dci.2015.07.017.

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14

Butler, J. E., and W. R. Brown. "The immunoglobulins and immunoglobulin genes of swine." Veterinary Immunology and Immunopathology 43, no. 1-3 (1994): 5–12. http://dx.doi.org/10.1016/0165-2427(94)90114-7.

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15

Wagner, Bettina. "Immunoglobulins and immunoglobulin genes of the horse." Developmental & Comparative Immunology 30, no. 1-2 (2006): 155–64. http://dx.doi.org/10.1016/j.dci.2005.06.008.

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16

Korhonen, Hannu, P. Marnila, and H. S. Gill. "Milk immunoglobulins and complement factors." British Journal of Nutrition 84, S1 (2000): 75–80. http://dx.doi.org/10.1017/s0007114500002282.

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The importance of colostrum for the growth and health of newborn offspring is well known. In bovine colostrum, the antibody (immunoglobulin) complement system provides a major antimicrobial effect against a wide range of microbes and confers passive immunity until the calf's own immune system has matured. Bovine serum and lacteal secretions contain three major classes of immunoglobulins: IgG, IgM and IgA. The immunoglobulins are selectively transported from the serum into the mammary gland, as a result of which the first colostrum contains very high concentrations of immunoglobulins (40–200 mg

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17

Wiese, Rick, Aliya Gessling, and David Hayes. "Multiplex immunoglobulin isotyping assays for human, mouse or rat serum samples (65.25)." Journal of Immunology 186, no. 1_Supplement (2011): 65.25. http://dx.doi.org/10.4049/jimmunol.186.supp.65.25.

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Abstract The determination of serum immunoglobulin isotype concentrations is an important indicator of immunological health. We have constructed several multiplex isotyping assays on the Luminex® assay platform. These assays allow for the analysis of human, mouse and rat serum, tissue culture or body fluid samples. The human isotyping assay enables the quantification of immunoglobulins A, M, G1, G2, G3 and G4 in a single assay well. While the mouse isotyping assay cover immunoglobulins A, M, G1, G2A, G2B, and G3, and the rat isotyping immunoglobulins A, E, M, G1, G2A, G2B, G2C. Since the conce

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18

Conti, Francesca, Mattia Moratti, Lucia Leonardi, et al. "Anti-Inflammatory and Immunomodulatory Effect of High-Dose Immunoglobulins in Children: From Approved Indications to Off-Label Use." Cells 12, no. 19 (2023): 2417. http://dx.doi.org/10.3390/cells12192417.

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Background: The large-scale utilization of immunoglobulins in patients with inborn errors of immunity (IEIs) since 1952 prompted the discovery of their key role at high doses as immunomodulatory and anti-inflammatory therapy, in the treatment of IEI-related immune dysregulation disorders, according to labelled and off-label indications. Recent years have been dominated by a progressive imbalance between the gradual but constant increase in the use of immunoglobulins and their availability, exacerbated by the SARS-CoV-2 pandemic. Objectives: To provide pragmatic indications for a need-based app

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19

Sokołowska, J., J. Micuń, K. Zabielska, E. Malicka, and R. Lechowski. "Immunohistochemical study of expression of immunoglobulins in canine B-cell lymphomas." Polish Journal of Veterinary Sciences 13, no. 4 (2010): 623–28. http://dx.doi.org/10.2478/v10181-010-0004-5.

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Immunohistochemical study of expression of immunoglobulins in canine B-cell lymphomasNineteen canine lymphomas were included in this study. Tumors were classified according to the updated Kiel classification adapted for canine lymphomas by Fournel-Fleury et al. Immunoglobulin light chains (κ and λ) and IgM and IgG expression were determined by immunohistochemical method. In all examined cases neoplastic cells were positive for one of the immunoglobulin light chains. Expression of λ light chains and κ light chains was observed in 18/19 and 1/19 tumors, respectively. In the majority of neoplasti

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20

Tsavaris, N., D. Tsigalacis, C. Kosmas, et al. "Preliminary Evaluation of the Potential Prognostic Value of Serum Levels of Immunoglobulins (IgA, IgM, IgG, IgE) in Patients with Gastric Cancer." International Journal of Biological Markers 13, no. 2 (1998): 87–91. http://dx.doi.org/10.1177/172460089801300204.

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Sixty patients with advanced gastric carcinoma who refused to receive cytotoxic chemotherapy were examined for serum immunoglobulin levels (IgG, IgM, IgA, IgE). Three samples were obtained every two months thereafter. The group of patients who had above-normal values of one or more of the examined immunoglobulins had a longer survival than the other (p<0.024). Immunoglobulin values were independent of the Helicobacter pylori antibody titer and of acute phase reactants. It is concluded that survival potentially correlates with serum immunoglobulin levels. Further studies including larger num

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21

Kouvalainen, K., and I. Moilanen. "Intrapair Similarity of Immunoglobulin Levels in Twins." Acta geneticae medicae et gemellologiae: twin research 36, no. 4 (1987): 509–15. http://dx.doi.org/10.1017/s0001566000006887.

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AbstractLevels of immunoglobulins IgG, IgA, IgM and IgE were determined in 8 MZ and 14 DZ twin pairs at the ages of 6-11 years, 12-17 years and 15-20 years. Intrapair similarity in immunoglobulin levels was found to be higher in the MZ than in the DZ twins, especially in the case of immunoglobulins IgA and IgM.

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Zweig, M. H., G. Csako, C. C. Benson, B. D. Weintraub, and B. B. Kahn. "Interference by anti-immunoglobulin G antibodies in immunoradiometric assays of thyrotropin involving mouse monoclonal antibodies." Clinical Chemistry 33, no. 6 (1987): 840–44. http://dx.doi.org/10.1093/clinchem/33.6.840.

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Abstract "Sandwich"-type assays are subject to positive interference by the patient's "heterophile" antibodies. If present, these bind to the animal immunoglobulins in the assay reagents, forming artefactual sandwiches indistinguishable from those formed with the analyte itself. Immunoglobulins from non-immunized animals, added to the assay reagents, can diminish this effect by blocking the patient's antibodies. Elsewhere, we studied several patients with anti-mouse immunoglobulin activity, whose serum gave spuriously high results for thyrotropin (TSH) concentrations. Here we have studied this

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Machado Neto, Raul, Irineu Umberto Packer, Gladys Villas Boas do Prado, Rosana Bessi, and Patricia Pauletti. "Colostral immunoglobulins absorption in Canchim and Nelore calves." Revista Brasileira de Zootecnia 33, no. 6 (2004): 1544–47. http://dx.doi.org/10.1590/s1516-35982004000600021.

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The efficiency of absorption of colostral immunoglobulins was evaluated in five Canchim and seven Nelore calves. They received colostrum pools with concentration of 70.20 ± 6.14 mg/mL through esofageal feeder at 2, 12, 24 and 36 hours after birth. The immunoglobulins concentrations of the pools were estimated through specific gravity and measured by radial immunodifusion. In the blood collection at birth and during the first 70 days of life, the total protein was assayed by biuret method and the immunoglobulins were assayed by radial immunodifusion. Data were analysed as a randomized split-plo

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Dimitroglou, Margarita, Rozeta Sokou, Nicoletta Iacovidou, et al. "Anti-SARS-CoV-2 Immunoglobulins in Human Milk after Coronavirus Disease or Vaccination—Time Frame and Duration of Detection in Human Milk and Factors That Affect Their Titers: A Systematic Review." Nutrients 15, no. 8 (2023): 1905. http://dx.doi.org/10.3390/nu15081905.

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Human milk (HM) of mothers infected with or vaccinated against SARS-CoV-2 contains specific immunoglobulins, which may protect their offspring against infection or severe disease. The time frame and duration after infection or vaccination, during which these immunoglobulins are detected in HM, as well as the major factors that influence their levels, have not been fully elucidated. This systematic review aimed to collect the existing literature and describe the immune response, specifically regarding the immunoglobulins in HM after COVID-19 disease or vaccination in non-immune women. We conduc

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Pohanka, M. "Evaluation of Immunoglobulin Production during Tularaemia Infection in BALB/c Mouse Model." Acta Veterinaria Brno 76, no. 4 (2007): 579–84. http://dx.doi.org/10.2754/avb200776040579.

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The chromatographic technique was used for assay of time-dependent content of antibodies in mice BALB/c infected by tularaemia. The assay was consequently performed on two types of chromatographic sorbents. The first was commercial CBindTM specific for serum immunoglobulins IgM, IgG and IgA. The second was originally prepared sorbent including protein G covalently bound on EnzacrylRAH particles. This sorbent has specificity for immunoglobulin IgG and its subclasses only. Finally, mass concentration of immunoglobulins in serum was determined. Two curves expressing time behavior of immunoglobuli

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Campos-Neto, Antonio, Isabelle Suffia, Karen A. Cavassani, et al. "Cloning and Characterization of a Gene Encoding an Immunoglobulin-Binding Receptor on the Cell Surface of Some Members of the Family Trypanosomatidae." Infection and Immunity 71, no. 9 (2003): 5065–76. http://dx.doi.org/10.1128/iai.71.9.5065-5076.2003.

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ABSTRACT Several members of the Trypanosomatidae family, when freshly isolated from their mammalian hosts, have immunoglobulins adsorbed to their cell surfaces. However, a significant portion of these antibody molecules is not parasite specific, i.e., the immunoglobulins are bound to the parasite's cell surface molecules via noncognitive interactions. It has been proposed that this noncognitive adsorption of immunoglobulins to the parasite is mediated by an Fc-like receptor present in several members of the Trypanosomatidae family. However, the molecular identification of this receptor has nev

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Kim, Hwan Keun, Fabiana Falugi, Dominique Missiakas, and Olaf Schneewind. "Expression of two immunoglobulin binding proteins is necessary for S. aureus to avoid host mediated innate and adaptive immune systems (P3138)." Journal of Immunology 190, no. 1_Supplement (2013): 186.16. http://dx.doi.org/10.4049/jimmunol.190.supp.186.16.

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Abstract Human or animal infections with S. aureus do not elicit protective immunity against staphylococcal diseases. Staphylococci are notorious to deploy a wide spectrum of strategies to avoid host immune system. Previous work revealed that both innate and adaptive immune systems are hampered by the expression of two immunoglobulin binding proteins; staphylococcal protein A (SpA) and staphylococcal binder of immunoglobulins (Sbi). Staphylococcal protein A, a molecule that associates with both Fc and Fab portions of immunoglobulins, is necessary 1) to neutralize the antibody mediated opsonoph

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Westhrin, Marita, Vlado Kovcic, Albert Bondt, et al. "Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma." Blood 134, Supplement_1 (2019): 4324. http://dx.doi.org/10.1182/blood-2019-122542.

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About 80% of patients with multiple myeloma develop a severe osteolytic bone disease causing pain and fractures. The myeloma cells secrete immunoglobulins and the presence of monoclonal immunoglobulins in serum is a hallmark of the disease. Immunoglobulins play a role in bone loss, but have not been linked with the bone disease in multiple myeloma. In this work, we isolated immunoglobulins from serum of myeloma patients using protein G coupled magnetic beads and columns. We found that immunoglobulins from patients with bone disease (n=16) promoted osteoclast differentiation when added to human

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Olaniyan, Mathew Folaranmi, and Musa Abidemi Muhibi. "Immunoglobulins as Tools for Passive Immunization in Preventive Healthcare." Journal of Primary Care Specialties 5, no. 3 (2024): 141–50. http://dx.doi.org/10.4103/jopcs.jopcs_24_23.

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Immunoglobulins have emerged as an important tool in passive immunization for the prevention and treatment of infectious diseases. Immunoglobulins are the proteins produced by B cells that bind to specific pathogens, neutralize them, and facilitate their removal by the immune system. In preventive healthcare, immunoglobulins are used for primordial, primary, secondary, tertiary, and quaternary prevention of infectious diseases. This work was designed to carry out an extensive literature search to provide useful information on immunoglobulins as the tools of passive immunization in preventive h

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Mehdiratta, N. K., and H. P. Singh. "Immunogobulins and Thermal Burns Infections." Indian Journal of Plastic Surgery 20, no. 01 (1987): 018–22. http://dx.doi.org/10.1055/s-0043-1772536.

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SummaryBurns patients have higher susceptibility to infections, causes of which are many fold. Leakage of immunoglobulins in blister fluid is one of them. The present work was undertaken to find out the relationship between the types of infections and the levels of various immunoglobulins in the sera of burn patients. Radial immunodiffusion technique of Mancini was utilized to measure the levels. It was observed that all types of infections produced rise in immunoglobulin levels. In mixed and Pseudomonas infections the rise of all major immunoglobulins was found statistically insignificant whi

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Wijetilleka, Sonali, David Jayne, Chetan Mukhtyar, and Mohammed Yousuf Karim. "Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases." Lupus Science & Medicine 6, no. 1 (2019): e000337. http://dx.doi.org/10.1136/lupus-2019-000337.

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B-cell targeted therapies (BCTT) are now widely used in autoimmune rheumatic diseases, including SLE, antineutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis. Early studies suggested that rituximab did not influence serum immunoglobulins. However, subsequently, with increased patient numbers, longer follow-up duration and many patients having received multiple BCTT courses, multiple subsequent studies have identified hypogammaglobulinaemia as a potential side effect. Patients developing hypogammaglobulinaemia appear to fit into two principal categories: the majority

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Ha, Seungmin, Sangjin Lee, Yeiju Park, et al. "The Association between Colostral density and immunoglubulin concentrations of Dairy Cattle." Journal of Immunology 204, no. 1_Supplement (2020): 92.6. http://dx.doi.org/10.4049/jimmunol.204.supp.92.6.

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Abstract The colostrum contains diverse and numerous immunoglobulins. The neonatal calf obtains majority of passive immunity from colostrum, which especially has huge effects on calf health. Historically, the amount of immunoglobulins in colostrum has been predicted through the density of the colostrum, but this correlation has not yet been clearly determined. In this study, we determined the correlation between the density and the immunoglobulin concentration, the difference between Holstein and Jersey cattle, and the impact by parity number. Densities were measured with Cruise densimeter. Th

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Lü, F. Xusheng, Zhongmin Ma, Tracy Rourke, Seema Srinivasan, Michael McChesney, and Christopher J. Miller. "Immunoglobulin Concentrations and Antigen-Specific Antibody Levels in Cervicovaginal Lavages of Rhesus Macaques Are Influenced by the Stage of the Menstrual Cycle." Infection and Immunity 67, no. 12 (1999): 6321–28. http://dx.doi.org/10.1128/iai.67.12.6321-6328.1999.

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ABSTRACT The levels of antigen-specific antibodies (Abs) and immunoglobulins in the cervical mucus of women vary with the menstrual cycle; the highest levels occur during menses, and the lowest occur during the periovulatory period. The rhesus macaque is a widely used animal model of female genital tract immunity. We sought to determine whether rhesus macaques have a cyclical pattern of changing cervicovaginal Ab and immunoglobulin levels that is similar to that of the human female. This study examined the relationship of the stages of the menstrual cycle to genital mucosal and systemic immuno

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Stenfors, Lars-Eric, Helga-Marie Bye, and Simo Räisänen. "Bacterial coating with immunoglobulins on the palatine tonsils during infectious mononucleosis: immunocytochemical study with gold markers." Journal of Laryngology & Otology 115, no. 2 (2001): 101–5. http://dx.doi.org/10.1258/0022215011907686.

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Epithelial cells and bacteria were sampled from the tonsillar surfaces of seven patients (six males, one female; median age 16 years, range 10 to 21 years) suffering from acute infectious mononucleosis with concomitant pharyngotonsillitis. By using gold-labelled antiserum to human IgG and secretory IgA (sIgA), micro-organisms on the tonsillar surfaces coated with these immunoglobulins could be identified by tracing the gold particles in the transmission electron microscope. The patients harboured significantly fewer bacteria coated with immunoglobulins than did healthy controls. More bacteria

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Dimopoulos, Meletios A., Argiris S. Symeonidis, Flora Zagouri, et al. "Preserved Levels Of Uninvolved Immunoglobulins Are Associated With Better Overall Survival In Patients With Multiple Myeloma Independently Of Disease Burden: A Role For The Immune System?" Blood 122, no. 21 (2013): 1866. http://dx.doi.org/10.1182/blood.v122.21.1866.1866.

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Abstract Suppression of uninvolved immunoglobulins is a common finding in MM patients. The prognostic importance of this finding has not been extensively studied in patients with MM and current data come from older series which included limited number of patients. Recent publications indicated that a novel immunoassay, which measures serum concentrations of the Ig heavy chain/light chain subsets IgGκ, IgGλ, IgAκ and IgAλ and which also identifies suppression of the uninvolved (polyclonal) Ig of the same isotype as the tumor was of prognostic significance for progression free survival in a sele

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 693 (1998): 12. http://dx.doi.org/10.2165/00128415-199806930-00040.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 709 (1998): 7. http://dx.doi.org/10.2165/00128415-199807090-00025.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 719 (1998): 8. http://dx.doi.org/10.2165/00128415-199807190-00026.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 727 (1998): 8. http://dx.doi.org/10.2165/00128415-199807270-00024.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 734 (1999): 8. http://dx.doi.org/10.2165/00128415-199907340-00022.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 737 (1999): 8. http://dx.doi.org/10.2165/00128415-199907370-00027.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 749 (1999): 9. http://dx.doi.org/10.2165/00128415-199907490-00022.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 1170 (2007): 21–22. http://dx.doi.org/10.2165/00128415-200711700-00053.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 1170 (2007): 22. http://dx.doi.org/10.2165/00128415-200711700-00058.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 1193 (2008): 17. http://dx.doi.org/10.2165/00128415-200811930-00053.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 540 (1995): 9. http://dx.doi.org/10.2165/00128415-199505400-00029.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 547 (1995): 7. http://dx.doi.org/10.2165/00128415-199505470-00019.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 553 (1995): 8. http://dx.doi.org/10.2165/00128415-199505530-00029.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 559 (1995): 8. http://dx.doi.org/10.2165/00128415-199505590-00021.

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&NA;. "Immunoglobulins." Reactions Weekly &NA;, no. 589 (1996): 8. http://dx.doi.org/10.2165/00128415-199605890-00024.

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