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Letteratura scientifica selezionata sul tema "ISOSATIVAN"

Autore: Grafiati

Pubblicato: 11 settembre 2023

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Articoli di riviste sul tema "ISOSATIVAN"

Sami, Bawazeer, Henry Okoro, Ngozichukwuka Igoli e John Igoli. "Isolation of Isosativan from Nigerian Red Propolis". Tropical Journal of Natural Product Research 4, n. 3 (30 marzo 2020): 77–79. http://dx.doi.org/10.26538/tjnpr/v4i3.3.

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Onay, M., e A. K. Onay. "Theoretical calculations and structural and electronic properties of isoflavanes: arvensan and isosativan". Acta Horticulturae, n. 1145 (novembre 2016): 97–100. http://dx.doi.org/10.17660/actahortic.2016.1145.15.

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Ingham, John L. "A Further Investigation of Phytoalexin Formation in the Genus Trifolium". Zeitschrift für Naturforschung C 45, n. 7-8 (1 agosto 1990): 829–34. http://dx.doi.org/10.1515/znc-1990-7-814.

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Abstract (sommario):

Abstract An earlier study of phytoalexin formation in the genus Trifolium has now been extended to include a further 61 species and subspecies. Using the drop-diffusate method, isoflavonoid phytoalexins were isolated from the fungus-inoculated leaflets of 55 accessions, whilst four others produced the stilbene derivative resveratrol. Phytoalexins could not be obtained from the leaflets of two species, T. billardieri and T. grandiflorum. The pterocarpan medicarpin was the most commonly encountered phytoalexin, occurring alone or in various combinations with the known Trifolium isofjavonoids maackiain (pterocarpan), vestitol, isovestitol, sativan, isosativan and arvensan (all isoflavans). Two additional pterocarpans, 4-methoxymedicarpin from T. cherleri and T. pallescens, and 4-hydroxyhomopterocarpin also from T. pallescens, were recognized for the first time as Trifolium phytoalexins. Re-examination of T. aureum re- vealed that this species produced resveratrol as a phytoalexin and not the isoflavan vestitol as previously described.

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Li, Qing, Dang Quan Zhang, Qi Mei Liu e Kuan Peng. "Determination of Bioactive Components of 60°С Volatiles from Cinnamomum camphora Branches by TD-GC/MS". Advanced Materials Research 230-232 (maggio 2011): 852–56. http://dx.doi.org/10.4028/www.scientific.net/amr.230-232.852.

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The chemical components of helium volatiles from the fresh branches of Cinnamomum camphora were studied by TD-GC/MS. The analytical result by 60°С-based TD-GC/MS showed that 55 peaks were obtained from the helium volatiles from the fresh branches of Cinnamomum camphora and 53 chemical compounds were identified. The results showed that the main components were as: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)- (15.4328%), 1,3-Benzodioxole, 5-(2-propenyl)- (14.881%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (12.694%), p-menth-1-en-8-ol (9.832%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3- pentenyl)-, (1S-exo)- (6.143%), 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- (5.365%), Bicyclo[3.1.1] hept-2-ene, 2,6-dimethyl-6-(4-methyl-3-pentenyl)- (4.527%), Naphthalene, 1,2,3,5,6,8a- hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1S-cis)- (4.129%), 3-Cyclohexen-1-ol, 4-methyl-1- (1-methylethyl)- (2.965%), Borneol (2.627%), Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, acetate, (1S-endo)- (2.586%), Copaene (2.534%), 1,6,10-Dodecatriene, 7,11-dimethyl-3-methylene-, (Z)- (1.612%), (-)-Isosativene (1.121%), etc. The analytical result suggested that the helium volatiles from the fresh branches of Cinnamomum camphora could be used as industrial materials of biomedicines and spicery.

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Аксенова (Aksenova), Юлия (Yuliya) Борисовна (Borisovna), Ирина (Irina) Викторовна (Viktorovna) Лапко (Lapko), Ольга (Ol'ga) Витальевна (Vital'evna) Кузнецова (Kuznetsova), Сергей (Sergej) Валерьевич (Valer'evich) Василевский (Vasilevskiy), Алексей (Аleksej) Вадимович (Vadimovich) Аксенов (Aksenov), Виктор (Viktor) Федорович (Fedorovich) Таранченко (Taranchenko), Андрей (Аndrej) Михайлович (Mikhajlovich) Антохин (Antochin), Игорь (Igor') Александрович (Аleksandrovich) Родин (Rodin) e Олег (Oleg) Алексеевич (Аlekseevich) Шпигун (Shpigun). "COMPARATIVE ANALYSIS OF QUALITATIVE AND QUANTITATIVE COMPOSITION OF DIFFERENT KINDS OF CINNAMON BARK (CINNAMOMUM)". chemistry of plant raw material, n. 3 (27 marzo 2018): 159–67. http://dx.doi.org/10.14258/jcprm.2018033805.

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Abstract (sommario):

The qualitative and quantitative composition of four types of cinnamon bark (Cinnamomum) was studied by gas chromatography with mass spectrometric detection.Found in these samples were 72 compounds of various classes, including terpenes, aldehydes, alcohols, organic acids, coumarins, esters, catechins, vitamins, sterols, and sugars. As a result of the comparative analysis, the specific compounds were found that are characteristic for Cinnamomum zeylanicum (3-tuyen, 4 (10) -tuyen, eugenol, (-)-α-curcumen, linolenic acid and for a group of Cinnamomum burmannii, Cinnamomum loureiroi and Cinnamomum Cassia, namely, sativene, isosativene, longicyclene, β-elemen, γ-mourolen, α-mourolen, α-calacorene, syrinaldehyde, and syringol. The presence of common compounds with certain concentration variability was revealed for all four types of cinnamon. The selection of the most informative compounds allowing species differentiation of the cinnamon bark has been carried out by the method of main components. Among these, four components (eugenol, α-mourolen, syrinaldehyde and linolenic acid) and specific and 12 components, such as cinnamic aldehyde, α-fellandrene, limonene, linalool, copaene, caryophyllene, coumarin, benzyl benzoate, cinnamic acid, palmitic acid, linoleic acid, and disaccharides, have common origin. Further research will be directed toward establishing the criteria that would allow species differentiation of the cinnamon bark of Cinnamomum zeylanicum, Cinnamomum burmannii, Cinnamomum loureiroi and Cinnamomum Cassia types.

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Liu, Qi Mei, e Wan Xi Peng. "80°С-Based TD-GC/MS Analysis of Chemical Components from Branches of Cinnamomum camphora". Key Engineering Materials 480-481 (giugno 2011): 466–71. http://dx.doi.org/10.4028/www.scientific.net/kem.480-481.466.

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Abstract (sommario):

The analytical result by 80°С-based TD-GC/MS showed that 65 peaks were obtained from the helium volatiles from the fresh branches of Cinnamomum camphora and 60 chemical compounds were identified. The results showed that the main components were as: 1,3-Benzodioxole, 5-(2-propenyl)- (12.629%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (10.302%), 3-Cyclohexene-1-methanol, .alpha.,.alpha.4-trimethyl- (9.084%), Bicyclo[2.2.1] heptan-2-one, 1,7,7-trimethyl-, (1R)- (7.406%), Nerolidol (6.695%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3-pentenyl)-, (1S-exo)- (6.017%), Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (.+/-.)- (4.885%), Bicyclo[3.1.1]hept-2-ene, 2,6-dimethyl-6-(4-methyl-3-pentenyl)- (4.680%), Naphthalene, 1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1S-cis)- (4.139%), 3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-, (R)- (3.538%), Copaene (2.749%), Bicyclo[2.2.1] heptan-2-ol, 1,7,7-trimethyl-, (1S-endo)- (2.643%), Acetic acid, 1,7,7-trimethyl-bicyclo [2.2.1]hept-2-yl ester (2.536%), Cyclohexane, bromo- (2.530%), 1,6,10-Dodecatriene, 7,11- dimethyl-3-methylene-, (E)- (1.725%), Naphthalene, 1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4- methylene-1-(1-methylethyl)-, (1.alpha.,4a.beta.,8a.alpha.)- (1.265%), Bicyclo[4.4.0]dec-1-ene, 2-isopropyl-5-methyl-9-methylene- (1.174%), (-)-Isosativene (1.149%), 11-Tetradecen-1-ol acetate (1.118%), .alpha.-Cadinol (1.061%), etc. The analytical result suggested that the helium volatiles from the fresh branches of C. camphora could be used as industrial materials of biomedicines, spicery and food industry.

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Liu, Qi Mei, Dang Quan Zhang, Kuan Peng e Wan Xi Peng. "Deep Analysis on Bioindustry Prospects of 40°С Volatiles of Cinnamomum camphora Branches". Key Engineering Materials 480-481 (giugno 2011): 266–71. http://dx.doi.org/10.4028/www.scientific.net/kem.480-481.266.

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Abstract (sommario):

Cinnamomum camphora has been used to heal some specific diseases in the Chinese Folk for a long time. In order to explore the wide utilization in biomedicine and spicery, the chemical components of helium volatiles from the fresh branches of C. camphora were studied by TD-GC/MS. The analytical result by TD-GC/MS showed that 50 peaks were obtained from the helium volatiles from the fresh branches of C. camphora and 46 chemical compounds representing 99.993% of the total areas were identified. The results showed that the main components were as: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)- (9.620%), 3-Cyclohexene-1- methanol, .alpha.,.alpha.4-trimethyl- (9.425%), 1,3-Benzodioxole, 5-(2-propenyl)- (8.223%), Bicyclo[2.2.1]heptane, 2-methyl-3-methylene-2-(4-methyl-3-pentenyl)-, (1S-exo)- (7.541%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7-(4-methyl-3-pentenyl)-, (-)- (6.884%), Bicyclo[3.1.1] hept-2-ene, 2,6-dimethyl-6-(4-methyl-3-pentenyl)- (6.050%), Bicyclo[2.2.1]heptan-2-one, 1,7,7- trimethyl-, (1S)- (4.678%), 1,3-Benzodioxole, 5-(2-propenyl)- (4.500%), Naphthalene, 1,2,3,5,6,8a- hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1S-cis)- (4.491%), 3-Cyclohexen-1-ol, 4-methyl-1- (1-methylethyl)-, (R)- (4.254%), Copaene (4.120%), Tricyclo[2.2.1.0(2,6)]heptane, 1,7-dimethyl-7- (4-methyl-3-pentenyl)-, (-)- (4.097%), Acetic acid, 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester (3.574%), Borneol 3.334%), 3-(4-N,N-Dimethylaminophenyl)propenoic acid, 2- (diethoxyphosphinyl)-, ethyl ester (2.809%), Eucalyptol (2.096%), 1,6,10-Dodecatriene, 7,11- dimethyl-3-methylene-, (Z)- (1.885%), (-)-Isosativene (1.664%), 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl- (1.407%), Cyclohexene, 1-methyl-4-(5-methyl-1-methylene-4-hexenyl)-, (S)- (1.218%), 1,4-Methanoazulene, decahydro-4,8,8-trimethyl-9-methylene-, [1S-(1.alpha.,3a.beta., 4.alpha.,8a.beta.)]- (1.174%), .alpha.-Caryophyllene (1.156%), etc. The analytical result suggested that the helium volatiles from the fresh branches of C. camphora can be applicable to biomedicine and spicery industrial materials.

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Tesi sul tema "ISOSATIVAN"

SINGH, SIMRAN. "EXPLORING NATURAL COMPOUNDS TARGETING THE HIPPO PATHWAY FOR POTENTIAL TREATMENT OF MENINGIOMA". Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/19944.

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Abstract (sommario):

Drug development which is a bit challenging and complex process that involves the development, discovery, design, and assessment of potential therapeutic agents. Meningioma, most common among the brain tumor which are generally asymptomatic in nature is characterized by the NF2 gene loss. The current treatment options such as resection and radiotherapy have limitations, with high rates of relapse or recurrence. The lack of FDA-approved drugs specific to meningioma necessitates the exploration of alternative approaches. Currently combination of FDA approved drug for other cancer were given to patients but the side effects and failure rates were high. To battle meningioma, natural substances are being researched as potential inhibitors of particular pathways, such as the YAP/TEAD complex in the Hippo signaling pathway. YAP/TEAD complex is responsible for uncontrolled cell progression in meningioma , by targeting this complex we can make a drug or treatment of meningioma. In this study, molecular docking was used to undertake in silico work and inhibition approach was used to find naturally occurring molecules with comparable structures that might potentially interact with the target receptor. out of 50 phytochemical,10 were selected on the basis of bioavailability test and lead likeness The white mulberry Morus alba plant's bark flavonoid, sanggenon N, was discovered to be the study's lead substance. Sanggenon N may have lesser negative effects than synthetic medications because the Sanggenon family of chemicals has demonstrated therapeutic potential. Another flavonoid called isostaivan showed the second-highest binding affinity.. Further analysis confirmed that Sanggenon N could act as an inhibitor of the 6UYC protein, which is the TEAD complex in Homo sapiens, thereby inhibiting the YAP/TEAD complex. This inhibition can potentially suppress cell proliferation and tumor growth in meningioma. It is crucial to emphasize that these results are based on in silico work and that additional validation through wet lab research is required.

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