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1

Andracki, Thaddeus. "Just Jake by Jake Marcionette." Bulletin of the Center for Children's Books 67, no. 7 (2014): 366–67. http://dx.doi.org/10.1353/bcc.2014.0183.

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2

Chudnov, Daniel, Cynthia Crooker, and Kimberly Parker. "jake." Serials Review 26, no. 4 (December 2000): 12–17. http://dx.doi.org/10.1080/00987913.2000.10764619.

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3

Major, Genée Ciurus. "Everything’s Jake." English Journal 107, no. 2 (November 1, 2017): 31–34. http://dx.doi.org/10.58680/ej201729352.

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This article explores the compassion created when students ask essential questions about life and death. The author describes her personal journey with her students as they experience what it means to be human.
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4

Gonzalez-Traves, P., B. Murray, F. Campigotto, A. Meng, and J. A. DI Paolo. "THU0067 JAK SELECTIVITY AND THE IMPACT ON CYTOKINE SIGNALING INHIBITION AT CLINICAL RHEUMATOID ARTHRITIS DOSES." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 246.1–246. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2074.

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Background:Janus kinase 1 (JAK1) inhibitors are efficacious in rheumatoid arthritis (RA). Despite having similar efficacy, in vitro studies have shown differences in JAK selectivity profiles for the small-molecule JAK inhibitors (JAKi) baricitinib (BARI), tofacitinib (TOFA), and upadacitinib (UPA).1For example, BARI and UPA are JAK1/JAK2 selective, while TOFA is JAK1/JAK3 selective, but each JAKi has some activity against other JAKs. As JAKs form signaling pairs, differences in selectivity could lead to distinct pharmacologic profiles that may impact clinical efficacy and safety.Objectives:As
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5

Spaner, D., M. Iqbal, A. Navabi, K. Strenzke, and B. Beres. "Jake hard red spring wheat." Canadian Journal of Plant Science 100, no. 1 (February 1, 2020): 129–35. http://dx.doi.org/10.1139/cjps-2019-0130.

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Jake hard red spring wheat (Triticum aestivum L.) was developed using a modified bulk breeding method at the University of Alberta, Edmonton, AB. Jake is an awned, hollow-stemmed line with high yield potential, medium tall plants, and medium maturity. During the three years (2015–2017) of evaluation in the Parkland Wheat Cooperative test, Jake yielded 6% higher than the mean of all of the checks, and matured 0.7 and 1.7 d later than Parata and Splendor but 2.9 d earlier than Glenn. Jake was 91.2 cm tall, shorter than AC Splendor (95.8 cm), but similar in height to Glenn (91.8 cm) and Parata (9
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6

Nina Notman, special to C&EN. "Jacob “Jake” Eichhorn." C&EN Global Enterprise 100, no. 29 (August 22, 2022): 26. http://dx.doi.org/10.1021/cen-10029-obits3.

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7

MacDonald, Douglas. "Portrait of Jake." American Journal of Hospice and Palliative Medicine® 18, no. 4 (July 2001): 283–85. http://dx.doi.org/10.1177/104990910101800416.

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8

Weiss, Jillian. "Awakening to Jake." Missouri Review 41, no. 4 (2018): 116–33. http://dx.doi.org/10.1353/mis.2018.0050.

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9

Scaife, B. "John ("Jake") Stohlner." BMJ 324, no. 7352 (June 22, 2002): 1527e—1527. http://dx.doi.org/10.1136/bmj.324.7352.1527/e.

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10

Deverell, William, and Tom Sitton. "Forget it, Jake." Boom 3, no. 3 (2013): 3–7. http://dx.doi.org/10.1525/boom.2013.3.3.3.

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This article places the 1974 film Chinatown alongside the historical events that the film portrays. Rather than a simple comparison between fact and fiction, Deverell and Sitton instead explore what we can learn about the people, places, and events in both Chinatown and the history of the Los Angeles aqueduct.
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11

Lees, J. A., P. R. Bown, and J. R. Young. "Jake Hancock: reminiscences." Proceedings of the Geologists' Association 117, no. 2 (January 2006): 125–27. http://dx.doi.org/10.1016/s0016-7878(06)80004-0.

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12

Brent Chesley. "Jake, It's Chinatown." Fourth Genre: Explorations in Nonfiction 4, no. 1 (2002): 172–82. http://dx.doi.org/10.1353/fge.2013.0071.

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13

Kennedy, W. J. "Jake Hancock 1928–2004." Mineralogical Magazine 68, no. 4 (August 2004): 712–13. http://dx.doi.org/10.1180/s0026461x00041815.

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14

Silver, Joel. "EXIT INTERVIEW: JAKE CHERNOFSKY." RBM: A Journal of Rare Books, Manuscripts, and Cultural Heritage 1, no. 1 (March 1, 2000): 77–82. http://dx.doi.org/10.5860/rbm.1.1.182.

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Jacob L. (“Jake”) Chernofsky recently retired from his position of editor and publisher of AB Bookman’s Weekly magazine, which he joined in 1973. AB, which was originally titled Antiquarian Bookman, was founded on January 3, 1948 by Sol. Malkin, and the magazine’s name was changed to AB Bookman’s Weekly in 1967, “in recognition of a readership comprising mostly specialist dealers.” AB, which had been widely read for several decades by people involved in the world of antiquarian books, suspended publication in December 1999. How did you get involved in antiquarian books and AB? I got involved i
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15

Sullivan, Jake. "Remarks by Jake Sullivan." Proceedings of the ASIL Annual Meeting 109 (2015): 341–42. http://dx.doi.org/10.5305/procannmeetasil.109.2015.0341a.

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16

Shannon, J. G., J. A. Wrather, D. A. Sleper, R. T. Robbins, H. T. Nguyen, and S. C. Anand. "Registration of ‘Jake’ Soybean." Journal of Plant Registrations 1, no. 1 (May 2007): 29–30. http://dx.doi.org/10.3198/jpr2006.05.0347crc.

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17

Tacchi, Derek. "James (“Jake”) Knox Russell." BMJ 334, no. 7594 (March 22, 2007): 643.5–643. http://dx.doi.org/10.1136/bmj.39155.563796.be.

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18

Spisak, April. "Nightfall by Jake Halpern." Bulletin of the Center for Children's Books 69, no. 4 (2015): 200. http://dx.doi.org/10.1353/bcc.2015.0914.

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19

Doḡu, Hikmet. "BREAKFAST SPECIAL. Jake Tilson." Art Documentation: Journal of the Art Libraries Society of North America 9, no. 3 (October 1990): 151. http://dx.doi.org/10.1086/adx.9.3.27948246.

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20

Sponsel, Valerie. "Jake MacMillan (1924–2014)." Phytochemistry 115 (July 2015): 271–72. http://dx.doi.org/10.1016/j.phytochem.2014.11.001.

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21

Batten, David J., and Jim Kennedy. "Jake Hancock: an appreciation." Cretaceous Research 25, no. 4 (August 2004): 435–37. http://dx.doi.org/10.1016/j.cretres.2004.06.001.

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22

Anderson, Donna S., John H. Melby, and James L. Folcik. "A Short History of the “Jake” Niobrara Horizontal Oil Discovery, Weld County, Colorado." Mountain Geologist 52, no. 3 (July 1, 2015): 5–12. http://dx.doi.org/10.31582/rmag.mg.52.3.5.

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In late 2009, the EOG Resources Jake 2-01H horizontal well (Sec. 1, T11N, R63W, Weld County, CO) re-opened the Niobrara oil play in the DJ basin. The play for EOG was built on comprehensive geologic scrutiny across the entire DJ basin of Colorado and Wyoming. Niobrara tests in the original Hereford field, four miles east of the Jake discovery, had bypassed Niobrara pay. This data, along with a 1991-vintage horizontal well with a vertical core through the Niobrara B Chalk in the original Hereford field, set up the prospect around the Jake discovery. A proprietary 40 square-mile 3-D seismic surv
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23

Spisak, April. "The Well by Jake Wyatt." Bulletin of the Center for Children's Books 75, no. 7 (2022): 235. http://dx.doi.org/10.1353/bcc.2022.0151.

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24

Shankar, Guha. "Discovering Rastafari! by Jake Homiak." American Anthropologist 113, no. 3 (August 24, 2011): 508–9. http://dx.doi.org/10.1111/j.1548-1433.2011.01363.x.

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25

Silverstone, Daniel, and Joe Whittle. "‘Forget it, Jake. It’s Chinatown’." Police Journal: Theory, Practice and Principles 89, no. 1 (February 26, 2016): 70–84. http://dx.doi.org/10.1177/0032258x16631566.

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26

Ebright, Ryan. "Moby-Dick by Jake Heggie." Notes 71, no. 1 (2014): 140–41. http://dx.doi.org/10.1353/not.2014.0102.

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27

Epp, Jake. "Address: The Honourable Jake Epp." Health Promotion International 1, no. 4 (1986): 413–17. http://dx.doi.org/10.1093/heapro/1.4.413.

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28

Browne, Ray B. "Jake Page's Indian Crime Fiction." Journal of American Culture 26, no. 3 (September 2003): 291–312. http://dx.doi.org/10.1111/1542-734x.00093.

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29

Chauvier, Éric. "Amy et Jake. Care, réflexivité, négativité." Recherche en soins infirmiers N° 122, no. 3 (2015): 97. http://dx.doi.org/10.3917/rsi.122.0097.

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30

Stojanović, Đorđe, and Živojin Đurić. "TEORETSKO ZASNIVANJE KONTINUUMA JAKE-SLABE DRŽAVE." Srpska politička misao 38, no. 4 (2012): 95–120. http://dx.doi.org/10.22182/spm.3842012.5.

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31

Gussow, Leon. "The Jake Walk and Limber Trouble." Emergency Medicine News 26, no. 10 (October 2004): 48. http://dx.doi.org/10.1097/00132981-200410000-00045.

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32

Morrison, Hope. "Jake at Gymnastics by Rachel Isadora." Bulletin of the Center for Children's Books 68, no. 2 (2014): 110. http://dx.doi.org/10.1353/bcc.2014.0826.

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33

Krygier, John. "Jake Barton’s Performance Maps: An Essay." Cartographic Perspectives, no. 53 (March 1, 2006): 41–50. http://dx.doi.org/10.14714/cp53.361.

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Jake Barton, a New York-based designer, creates public maps that generate social interaction, personal expression, and collaborative storytelling. Barton’s work is centered on performance, drawing attention to the performative capacity of maps, a seldom-explored facet of cartographic design and theory. Examples of Barton’s projects, realized and unrealized, are detailed, with a focus on the manner in which maps are designed to evoke performance.
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34

O’Connell, Mark. "Review of A Kid Like Jake." Journal of the American Psychoanalytic Association 62, no. 2 (April 2014): 363–72. http://dx.doi.org/10.1177/0003065114527612.

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35

Shanley, James B., James M. Buttle, and Richard P. Hooper. "Preface for Jake Peters' special issue." Hydrological Processes 34, no. 8 (February 8, 2020): 1680–81. http://dx.doi.org/10.1002/hyp.13710.

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36

Lovensheimer, Jim. "Mormons, Musical Theater, and Belonging in America, Jake Johnson (2019) Lying in the Middle: Musical Theater and Belief at the Heart of America, Jake Johnson (2021)." Studies in Musical Theatre 16, no. 3 (December 1, 2022): 248–51. http://dx.doi.org/10.1386/smt_00110_5.

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Review of: Mormons, Musical Theater, and Belonging in America, Jake Johnson (2019) Urbana, Chicago and Springfield, IL: University of Illinois Press, 199 pp., ISBN 978-0-25208-433-1, p/bk, $25.00 Lying in the Middle: Musical Theater and Belief at the Heart of America, Jake Johnson (2021) Urbana, Chicago and Springfield, IL: University of Illinois Press, 159 pp., ISBN 978-0-25208-599-4, p/bk, $24.95
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37

Avouac, Jérôme. "Janus Kinase Inhibitor Selectivity in Rheumatoid Arthritis: Where Do We Stand?" Rheumatology 1, no. 1 (2022): 5. http://dx.doi.org/10.17925/rmd.2022.1.1.5.

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The selectivity of Janus kinase inhibitors (JAKis) is still a matter of debate, as no JAKi is specific for only one Janus kinase (JAK) isoform. Currently approved JAKis in rheumatoid arthritis (RA) all inhibit JAK1, which is an effective therapeutic target in RA. Although selective JAK1 inhibition seems not to decrease drug efficacy, JAKi selectivity may modify the safety profile of this class. Indeed, the balance of benefit and risk of inhibiting JAK2, JAK3 and tyrosine kinase 2 is not certain and should be carefully evaluated in the future.
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38

Bangerter, Abigail, Nikolay V. Manyakov, David Lewin, Matthew Boice, Andrew Skalkin, Shyla Jagannatha, Meenakshi Chatterjee, et al. "Caregiver Daily Reporting of Symptoms in Autism Spectrum Disorder: Observational Study Using Web and Mobile Apps." JMIR Mental Health 6, no. 3 (March 26, 2019): e11365. http://dx.doi.org/10.2196/11365.

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Background Currently, no medications are approved to treat core symptoms of autism spectrum disorder (ASD). One barrier to ASD medication development is the lack of validated outcome measures able to detect symptom change. Current ASD interventions are often evaluated using retrospective caregiver reports that describe general clinical presentation but often require recall of specific behaviors weeks after they occur, potentially reducing accuracy of the ratings. My JAKE, a mobile and Web-based mobile health (mHealth) app that is part of the Janssen Autism Knowledge Engine—a dynamically update
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39

Palumbo, Matthew D., Francisco J. Vilella, Bronson K. Strickland, Guiming Wang, and Dave Godwin. "Brood Surveys and Hunter Observations Used to Predict Gobbling Activity of Wild Turkeys in Mississippi." Journal of Fish and Wildlife Management 5, no. 1 (January 1, 2014): 151–56. http://dx.doi.org/10.3996/032013-jfwm-023.

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Abstract The Mississippi Department of Wildlife, Fisheries, and Parks utilize data from turkey hunter observations and brood surveys from across the state to manage wild turkey Meleagris gallopavo populations. Since 1995, hunters have collected gobbling and jake observation data, while the Mississippi Department of Wildlife, Fisheries, and Parks' personnel and cooperating wildlife managers of several natural resource agencies throughout the state have collected brood survey data. Both sources of data serve to forecast poult recruitment and gobbling activity. The objective of this study was to
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40

Hernandez, Josefino. "Jacob S. Matubis, MD (1950-2022) “Bye, Jake!”." Philippine Journal of Otolaryngology Head and Neck Surgery 37, no. 1 (June 5, 2022): 63. http://dx.doi.org/10.32412/pjohns.v37i1.1943.

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 Those words reverberate in our minds as we remember how Dr. Nati Almazan, president of the Philippine Board of Otolaryngology- Head and Neck Surgery, bid Jake goodbye on many occasions, also being a member of the board.
 
 
 
 
 
 Dr. Jacob Sadang Matubis, a colleague, a brother in the Mu Sigma Phi fraternity, and a batchmate during our residency in Otolaryngology-Head and Neck Surgery at the University of the Philippines-Philippine General Hospital from 1981 to 1984, was a friend to many of us. Jake, as we fondly called him, was a memb
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41

Trihanto, Agung. "An Analysis on Directive Speech Act Found in Jumanji: The Next Level Movie Directed by Jake Kashan." International Journal of English Linguistics, Literature, and Education (IJELLE) 4, no. 1 (June 30, 2022): 13. http://dx.doi.org/10.32585/ijelle.v4i1.2175.

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Directive speech acts are words to order someone so the other people take action according to the request of the speaker both directly and indirectly. This study discusses about An Analysis of Directive Speech Acts Found in Jumanji: The Next Level Movie Directed by Jake Kashan. The purpose of this study is to identify the kinds and the forms of directive speech acts found in Jumanji: The Next Level movie directed by Jake Kashan. This research was conducted using qualitative method. The main instrument of this research is the researcher himself. The researcher as a human instrument used laptop,
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42

Danese, Silvio, Marjorie Argollo, Catherine Le Berre, and Laurent Peyrin-Biroulet. "JAK selectivity for inflammatory bowel disease treatment: does it clinically matter?" Gut 68, no. 10 (June 21, 2019): 1893–99. http://dx.doi.org/10.1136/gutjnl-2019-318448.

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The two major forms of inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), are chronic immune-mediated conditions characterised by an increased production of pro-inflammatory cytokines that act as critical drivers of intestinal inflammation. Anti-cytokine therapy has been shown to improve clinical outcomes in IBD. Janus kinases (JAKs) are tyrosine kinases that bind different intracellular cytokine receptors, leading to phosphorylation of signal transducer and activation of transcription molecules implicated on targeted gene transcription. Four isofo
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43

Constantinescu, Stefan N., Emilie Leroy, Vitalina Gryshkova, Christian Pecquet, and Alexandra Dusa. "Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers." Biochemical Society Transactions 41, no. 4 (July 18, 2013): 1048–54. http://dx.doi.org/10.1042/bst20130084.

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The discovery of the highly prevalent activating JAK (Janus kinase) 2 V617F mutation in myeloproliferative neoplasms, and of other pseudokinase domain-activating mutations in JAK2, JAK1 and JAK3 in blood cancers, prompted great interest in understanding how pseudokinase domains regulate kinase domains in JAKs. Recent functional and mutagenesis studies identified residues required for the V617F mutation to induce activation. Several X-ray crystal structures of either kinase or pseudokinase domains including the V617F mutant of JAK2 pseudokinase domains are now available, and a picture has emerg
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Wang, H. Y., J. Zamorano, J. L. Yoerkie, W. E. Paul, and A. D. Keegan. "The IL-4-induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK1 expression in human fibrosarcoma cells." Journal of Immunology 158, no. 3 (February 1, 1997): 1037–40. http://dx.doi.org/10.4049/jimmunol.158.3.1037.

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Abstract It has been shown that IL-4 induces the tyrosine phosphorylation of JAK1 and JAK3 in the majority of hemopoietic cell types, and JAK2 and TYK2 in several other types. However, the significance of this tyrosine phosphorylation in regulating IL-4 signaling has not been shown. To determine whether JAKs play a role in activating a signal transduction pathway different from the classical JAK/STAT pathway, we analyzed the ability of huIL-4 to stimulate the tyrosine phosphorylation of one of its major cellular substrates, the insulin receptor substrate (IRS). Using human fibrosarcoma cell li
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45

Evans, Colin. "Jake Thackray, Translator and Interpreter of Brassens." Équivalences 22, no. 1 (1992): 73–90. http://dx.doi.org/10.3406/equiv.1992.1153.

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Cowell, Eva Lynn. "UNDERSTANDING COMMUNICATION AND AGING By Jake Harwood." Educational Gerontology 34, no. 11 (October 22, 2008): 1034–35. http://dx.doi.org/10.1080/03601270802432332.

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47

Ramsey, Sarah Schwartzman. "Yekl to Jake: Reading Cahan with Arendt." Studies in American Jewish Literature (1981-) 42, no. 2 (September 1, 2023): 141–57. http://dx.doi.org/10.5325/studamerijewilite.42.2.0141.

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Abstract In Abraham Cahan’s 1896 novella, Yekl: A Tale of the New York Ghetto, Yekl/Jake is a Russian Jewish immigrant who repeats loud and self-aggrandizing accounts of himself as a proudly assimilated American. This article uses Hannah Arendt’s writing on cliché and her 1943 essay “We Refugees” to argue that Cahan’s depiction of Jake exemplifies a type of performance, one that Arendt witnessed among Jewish refugees during her own experiences of displacement: a pattern of narrative erasure and fabrication, alienation from community, and “insane optimism which is next door to despair” (Arendt
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48

Zhong, Haizhen A., and Suliman Almahmoud. "Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors." International Journal of Molecular Sciences 24, no. 7 (March 23, 2023): 6023. http://dx.doi.org/10.3390/ijms24076023.

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The Janus kinases (JAKs) are a family of non-receptor cytosolic protein kinases critical for immune signaling. Many covalently bound ligands of JAK3 inhibitors have been reported. To help design selective JAK inhibitors, in this paper, we used five model proteins to study the subtype selectivity of and the mutational effects on inhibitor binding. We also compared the Covalent Dock programs from the Schrodinger software suite and the MOE software suite to determine which method to use for the drug design of covalent inhibitors. Our results showed that the docking affinity from 4Z16 (JAK3 wild-t
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Liu, X., F. Tan, and C. Liang. "THU0080 PRECLINICAL CHARACTERIZATION OF TLL018, A NOVEL, HIGHLY POTENT AND SELECTIVE JAK1/TYK2 INHIBITOR FOR TREATING AUTOIMMUNE DISEASES." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 252.1–252. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1547.

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Background:Janus kinases (JAKs) are important regulators of intracellular responses triggered by many key proinflammatory cytokines and are clinically validated therapeutic targets for treating various autoimmune diseases. However, current approved JAK inhibitors failed to achieve maximal clinical benefit in part due to their unfavorable selectivity for individual JAKs such as JAK2 and/or JAK3, leading to dose-limiting toxicities or severe toxicities (e.g., thrombosis, anemia, immune suppression). Selective inhibition of JAK1 and/or TYK2 may minimize or avoid some of the toxicities and potenti
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50

Widayanto, Mutinda Teguh. "Sosialisasi Pembuatan Pokak Jahe Untuk Meningkatkan Imunitas Dimasa Pandemi Covid-19 di Sumberkedawung Leces Probolinggo." Dharma: Jurnal Pengabdian Masyarakat 1, no. 2 (June 10, 2021): 93–110. http://dx.doi.org/10.35309/dharma.v1i2.4531.

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Pandemi Covid-19 yang melanda hampir seluruh wilayah di dunia telah mempengaruhi berbagai sektor kehidupan masyarakat. Pembatasan kegiatan masyarakat karena menghindari penyebaran virus menyebabkan aqktivitas tidak bisa dilaksanakan sebagaimana mestinya. Bidang pendidikan, sosial dan ekonomi tak luput dari pengaruh tersebut. Upaya untuk mengatasi penularan virus juga dilakukan. Berbagai penelitian dilakukan untuk mengatasi permasalahan tersebut. Salah satu faktor yang dapat mengatasi dampak dari serangan virus adalah adanya imunitas tubuh yang baik. Minuman tradisional Pokak Jahe diketahui men
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