Letteratura scientifica selezionata sul tema "Leukemia inhibitory factor"

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Articoli di riviste sul tema "Leukemia inhibitory factor"

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Nicola, Nicos A., and Jeffrey J. Babon. "Leukemia inhibitory factor (LIF)." Cytokine & Growth Factor Reviews 26, no. 5 (2015): 533–44. http://dx.doi.org/10.1016/j.cytogfr.2015.07.001.

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Metcalf, Donald. "The leukemia inhibitory factor (LIF)." International Journal of Cell Cloning 9, no. 2 (1991): 95–108. http://dx.doi.org/10.1002/stem.5530090201.

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Pehlivan, Melek, Ceyda Caliskan, Zeynep Yuce, and Hakkı Ogun Sercan. "Forced expression of Wnt antagonists sFRP1 and WIF1 sensitizes chronic myeloid leukemia cells to tyrosine kinase inhibitors." Tumor Biology 39, no. 5 (2017): 101042831770165. http://dx.doi.org/10.1177/1010428317701654.

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Abstract (sommario):
Chronic myeloid leukemia is a clonal myeloproliferative disorder that arises from the neoplastic transformation of the hematopoietic stem cell, in which the Wnt/β-catenin signaling pathway has been demonstrated to play an important role in disease progression. However, the role of Wnt signaling antagonists in therapy resistance and disease progression has not been fully investigated. We aimed to study the effects of Wnt/β-catenin pathway antagonists—secreted frizzled-related protein 1 and Wnt inhibitory factor 1—on resistance toward tyrosine kinase inhibitors in chronic myeloid leukemia. Respo
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Na, Bon Hyang, Thi Xoan Hoang та Jae Young Kim. "Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-κB Activation in Human Myeloid Leukemia THP-1 Cells". BioMed Research International 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/4319369.

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Tumors highly express active heat shock protein 90 (Hsp90), which is involved in tumor survival and progression. Enhanced Toll-like receptor (TLR) 5 expression and signaling were reported to be associated with acute myeloid leukemia. In the present study, we investigated the possible modulatory effects of Hsp90 inhibitors on TLR5 expression and signaling in the human myeloid leukemia cell line THP-1. Cells were pretreated with various concentrations of the Hsp90 inhibitor geldanamycin (GA) or the Hsp70 inhibitor VER155008, followed by stimulation with bacterial flagellin. Flagellin-induced nuc
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Vanchieri, C. "Leukemia Inhibitory Factor Has Multiple Personalities." JNCI Journal of the National Cancer Institute 86, no. 4 (1994): 262. http://dx.doi.org/10.1093/jnci/86.4.262.

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Hinds, Mark G., Till Maurer, Jian-Guo Zhang, Nicos A. Nicola, and Raymond S. Norton. "Solution Structure of Leukemia Inhibitory Factor." Journal of Biological Chemistry 273, no. 22 (1998): 13738–45. http://dx.doi.org/10.1074/jbc.273.22.13738.

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Senturk, Levent M., and Aydin Arici. "Leukemia Inhibitory Factor in Human Reproduction." American Journal of Reproductive Immunology 39, no. 2 (1998): 144–51. http://dx.doi.org/10.1111/j.1600-0897.1998.tb00346.x.

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RAY, DAVID W., SONG-GUANG REN, and SHLOMO MELMED. "Leukemia Inhibitory Factor Regulates Proopiomelanocortin Transcriptiona." Annals of the New York Academy of Sciences 840, no. 1 (1998): 162–73. http://dx.doi.org/10.1111/j.1749-6632.1998.tb09560.x.

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Lass, Amir, Weishui Weiser, Alain Munafo, and Ernest Loumaye. "Leukemia inhibitory factor in human reproduction." Fertility and Sterility 76, no. 6 (2001): 1091–96. http://dx.doi.org/10.1016/s0015-0282(01)02878-3.

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Hilton, Douglas J., and Nicholas M. Gough. "Leukemia inhibitory factor: A biological perspective." Journal of Cellular Biochemistry 46, no. 1 (1991): 21–26. http://dx.doi.org/10.1002/jcb.240460105.

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Tesi sul tema "Leukemia inhibitory factor"

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Voyle, Roger Bruce. "Mechanisms of intracellular and extracellular cytokine production from the human leukaemia inhibitory factor gene." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phv975.pdf.

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Abstract (sommario):
Addendum attached to back facing leaves. Includes bibliographical references (leaves 172-199). The findings establish leukemia inhibitory factor, and possibly oncostatin M, as new members of a small but growing class of cytokines produced in an intracellularly active form and also suggest that the production of alternate transcripts and intercellularly-retained proteins may be a common and important feature of cytokines of the IL-6 and other families.
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Haines, Bryan Peter. "Alternate transcription and translation of the LIF gene produces a novel intracellular protein /." Title page, contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phh1518.pdf.

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Zhang, Xiyuan. "The expression of human leukemia inhibitory factor in Pichia pastoris." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29919.

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Abstract (sommario):
Background: Leukemia inhibitory factor (LIF) is an interleukin 6 class cytokine that inhibits cell differentiation during cell development. LIF is widely used as an important component in stem cell culture medium for cell therapy and tissue engineering applications, to inhibit spontaneous cell differentiation. However, commercially available recombinant LIF proteins are expensive, unstable, and prone to degradation in prolonged tissue culture, which has limited its applications. Purpose: We aim to develop a lab-scale method, using a yeast cell, namely, P. pastoris, to produce recombinant hL
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Hsu, Li-Wei. "Structure and expression of murine leukemia inhibitory factor (LIF) gene." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334839.

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Davis, Stephanie. "Leukemia Inhibitory Factor as a Neuroprotective Agent against Focal Cerebral Ischemia." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6218.

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Previous publications from this laboratory demonstrated that administration of leukemia inhibitory factor (LIF) (125 µg/kg) to young, male Sprague-Dawley rats at 6, 24, and 48 h after middle cerebral artery occlusion (MCAO) reduced infract volume, improved sensimotor skills, and alleviated damage to white matter at 72 h after the injury. In vitro studies using cultured oligodendrocytes (OLs) showed that LIF (200 ng/ml) also protects against 24 h of oxygen-glucose deprivation through activation of Akt signaling and upregulation of the antioxidant enzymes peroxiredoxin IV and metallothionein III
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Schiemann, William Paul. "Determination and characterization of leukemia inhibitory factor receptor signal transduction systems /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/6277.

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Ng, Yu Pong. "Leukemia inhibitory factor receptor signaling in NGF-induced neuronal differentiation of PC12 cells /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BICH%202004%20NG.

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Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2004.<br>Includes bibliographical references (leaves 134-172). Also available in electronic version. Access restricted to campus users.
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Alberti, Kristin. "Biologische Verfügbarkeit des Zytokins Leukemia inhibitory factor nach kovalenter Ankopplung an Polymeroberflächen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-65099.

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Für medizinische Anwendungen sind Stammzellen aufgrund ihrer Eigenschaften (Selbsterneuerung, hohe Proliferationsrate und Differenzierungsmöglichkeit in verschiedene Zelltypen) beispielsweise in den Bereichen des regenerativen Gewebeersatzes und der Zelltherapie sehr interessant. In vivo umgibt die Stammzellen eine definierte Mikroumgebung, die sie unterstützt sich zu teilen, ihren undifferenzierten Status aufrecht zu erhalten und Tochterzellen für das Wachstum, die routinemäßige Erneuerung oder den Ersatz von Gewebe zu produzieren. Diese Mikroumgebungen werden als Stammzellnischen bezeichnet.
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Port, Martha D. "Regulation of expression and function of neurokine receptors /." Thesis, Connect to this title online; UW restricted, 2008. http://hdl.handle.net/1773/6283.

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Gascan, Hugues. "Caracterisation du facteur de croissance hilda : leukemia inhibitory factor produit par des cellules tumorales humaines." Nantes, 1988. http://www.theses.fr/1988NANT04VS.

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Libri sul tema "Leukemia inhibitory factor"

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Paglia, Diana. The role of leukemia inhibitory factor in skin biology. National Library of Canada, 1996.

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2

Athanasius, Anagostou, Dainiak Nicholas, Najman Albert, and International Conference on Negative Regulators of Hematopoiesis, (2nd : 1990 : Providence, R.I.), eds. Negative regulators of hematopoiesis: Studies of their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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Oppmann, Birgit. Struktur- und Funktionsanalyse des humanen Leukemia Inhibitory Factor-Rezeptors. 1998.

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Gutenberg-Universität, Johannes, ed. Die Funktion von leukemia inhibitory factor in humanen hämatopoetischen In-vitro-Stammkulturen. 1997.

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Göllner, Gerhard. Regulation von Granulocyte-Makrophage Colony Stimulating Factor (GM-CSF) und Leukemia Inhibitory Factor (LIF) in murinen Knochenmark-Stromazellen. 1996.

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Negative regulators of hematopoiesis: Studies on their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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Anagnostou, Athanasius, and Nicholas Dainiak. Negative Regulators of Hematopoiesis: Studies on Their Nature, Action, and Potential Role in Cancer Therapy (Annals of the New York Academy of Scien). New York Academy of Sciences, 1991.

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Najman, Albert, Athanasius Anagnostou, and Nicholas Dainiak. Negative regulators of hematopoiesis : Studies on their nature, action, and potential role in cancer therapy. New York Academy of Sciences, 1991.

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Capitoli di libri sul tema "Leukemia inhibitory factor"

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Ratajczak, Mariusz Z. "Leukemia Inhibitory Factor." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_3324-4.

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Ratajczak, Mariusz Z. "Leukemia Inhibitory Factor." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_3324.

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Ratajczak, Mariusz Z. "Leukemia Inhibitory Factor." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_3324.

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Agca, Cavit, and Christian Grimm. "Leukemia Inhibitory Factor Signaling in Degenerating Retinas." In Retinal Degenerative Diseases. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-3209-8_49.

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Hooper, Marcus J., and John D. Ash. "Müller Cell Biological Processes Associated with Leukemia Inhibitory Factor Expression." In Retinal Degenerative Diseases. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-75402-4_59.

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Ravandi, Farhad, and Zeev Estrov. "The Role of Leukemia Inhibitory Factor in Cancer and Cancer Metastasis." In Growth Factors and their Receptors in Cancer Metastasis. Springer Netherlands, 2001. http://dx.doi.org/10.1007/0-306-48399-8_1.

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Tanaka, Masato, Tatsuya Yamashita, and Satoshi Terada. "The Effect of Interleukin-6 and Leukemia Inhibitory Factor on Hybridoma Cells." In Animal Cell Technology: Basic & Applied Aspects. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-9646-4_8.

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Ash, John D. "Leukemia Inhibitory Factor Prevents Photoreceptor Cell Death in rd-/- Mice by Blocking Functional Differentiation." In New Insights Into Retinal Degenerative Diseases. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1355-1_16.

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Torchinsky, A., U. R. Markert, and V. Toder. "TNF-&agr;-Mediated Stress-Induced Early Pregnancy Loss:A Possible Role of Leukemia Inhibitory Factor." In Chemical Immunology and Allergy. KARGER, 2005. http://dx.doi.org/10.1159/000087913.

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Fletcher, Frederick A., Kateri A. Moore, Douglas E. Williams, Dirk Anderson, Charles Maliszewski, and John W. Belmont. "Effects of Leukemia Inhibitory Factor (LIF) on Gene Transfer Efficiency into Murine Hematolymphoid Progenitors." In Mechanisms of Lymphocyte Activation and Immune Regulation III. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5943-2_15.

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Atti di convegni sul tema "Leukemia inhibitory factor"

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Quinton, Lee J., Joseph P. Mizgerd, Matthew R. Jones, and Eri Allen. "Endogenous Leukemia Inhibitory Factor Limits Acute Lung Injury During Pneumonia." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1090.

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Nair, Hareesh B., Bindu Santhamma, Surya Viswanadhapa, and Klaus J. Nickisch. "Abstract LB-208: First-in-class steroidal leukemia inhibitory factor (LIF) inhibitor in targeted cancer therapy." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-208.

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Poon, J., M. A. Campos, R. F. Foronjy, et al. "Cigarette Smoke Exposure Reduces Leukemia Inhibitory Factor Levels During Respiratory Syncytial Viral Infection." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4517.

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Chang, Xiaofei, Yong G. Cho, Il-Seok Park, et al. "Abstract 4799: Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4799.

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Nair, Hareesh B., Bindu Santhamma, Suryavathi Viswanadhapalli, et al. "Abstract LB-B04: Development of a first-in-class leukemia inhibitory factor (LIF)/LIFR inhibitor, EC359 for targeted therapy." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b04.

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Na, E., K. E. Traber, F. T. Korkmaz, et al. "Determining Epithelial-Specific Roles for the Lung-Protective Cytokine Leukemia Inhibitory Factor (LIF) During Pneumonia." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6166.

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Krasnapolski, Martin A., Ana Quaglino, Edith Kordon, and Elisa D. Bal de Kier Joffe. "Abstract 3121: Study of leukemia inhibitory factor (LIF) system in a murine mammary tumor comprising luminal and myoepithelial cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3121.

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Kamohara, Hidenobu, Yoshiharu Hiyoshi, Junji Kurashige, Koichi Kinoshita, Masaaki Iwatsuki, and Hideo Baba. "Abstract 4111: Induction of CXCL8 by TNFalpha and LIF (Leukemia Inhibitory Factor) in pancreatic carcinoma cells: Impact of CXCL8 as an autocrine growth factor." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4111.

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Banerjee, Priyanka, Baidyanath Chakravarty, and Koel Chaudhury. "Expression of αvβ3 integrin, leukemia inhibitory factor and pinopodes as markers of endometrial receptivity in idiopathic recurrent spontaneous miscarriage." In 2010 International Conference on Systems in Medicine and Biology (ICSMB). IEEE, 2010. http://dx.doi.org/10.1109/icsmb.2010.5735419.

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Iorns, Elizabeth J., Toby M. Ward, Sonja Dean, et al. "Abstract 4979: Whole genome in vivo RNA interference screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4979.

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Rapporti di organizzazioni sul tema "Leukemia inhibitory factor"

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Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

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The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env
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