Letteratura scientifica selezionata sul tema "MALDI"

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Articoli di riviste sul tema "MALDI"

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Osa, Morichika, Maria Cecilia Belo, Zita Dela Merced, et al. "Performance of MALDI–TOF Mass Spectrometry in the Philippines." Tropical Medicine and Infectious Disease 6, no. 3 (2021): 112. http://dx.doi.org/10.3390/tropicalmed6030112.

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Identification of the causative pathogen in infectious diseases is important for surveillance and to guide treatment. In low- and middle-income countries (LMIC), conventional culture and identification methods, including biochemical methods, are reference-standard. Biochemical methods can lack sensitivity and specificity and have slow turnaround times, causing delays in definitive therapy. Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI–TOF MS) is a rapid and accurate diagnostic method. Most studies comparing MALDI–TOF MS and biochemical methods are from hig
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KAWABATA, Shin-ichirou. "MALDI-TOFMS." Journal of the Japan Society of Colour Material 79, no. 6 (2006): 257–62. http://dx.doi.org/10.4011/shikizai1937.79.257.

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Kajiwara, Hideyuki. "MALDI biotyping." Nippon Shokuhin Kagaku Kogaku Kaishi 65, no. 11 (2018): 541. http://dx.doi.org/10.3136/nskkk.65.541.

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Wisztorski, Maxence, Rémi Lemaire, Jonathan Stauber, et al. "Imagerie MALDI." médecine/sciences 23 (March 2007): 31–38. http://dx.doi.org/10.1051/medsci/2007231s31.

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Chakrabarti, A. "MALDI-TOF." International Journal of Infectious Diseases 45 (April 2016): 26. http://dx.doi.org/10.1016/j.ijid.2016.02.090.

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Chin, Jefferson, Elizabeth Wood, Grace S. Peters, and Dieter M. Drexler. "Acoustic Sample Deposition MALDI-MS (ASD-MALDI-MS)." Journal of Laboratory Automation 21, no. 1 (2016): 204–7. http://dx.doi.org/10.1177/2211068215594769.

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Rim, John Hoon, Yangsoon Lee, Sung Kuk Hong, et al. "Insufficient Discriminatory Power of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Dendrograms to Determine the Clonality of Multi-Drug-ResistantAcinetobacter baumanniiIsolates from an Intensive Care Unit." BioMed Research International 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/535027.

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While pulsed-field gel electrophoresis (PFGE) is recognized as the gold standard method for clonality analysis, MALDI-TOF MS has recently been spotlighted as an alternative tool for species identification. Herein, we compared the dendrograms of multi-drug-resistant (MDR)Acinetobacter baumanniiisolates by using MALDI-TOF MS with those by using PFGE. We used direct colony and protein extraction methods for MALDI-TOF MS dendrograms. The isolates with identical PFGE patterns were grouped into different branches in MALDI-TOF MS dendrograms. Among the isolates that were classified as very close isol
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Chen, Xin-Fei, Xin Hou, Meng Xiao, et al. "Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) Analysis for the Identification of Pathogenic Microorganisms: A Review." Microorganisms 9, no. 7 (2021): 1536. http://dx.doi.org/10.3390/microorganisms9071536.

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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used in the field of clinical microbiology since 2010. Compared with the traditional technique of biochemical identification, MALDI-TOF MS has many advantages, including convenience, speed, accuracy, and low cost. The accuracy and speed of identification using MALDI-TOF MS have been increasing with the development of sample preparation, database enrichment, and algorithm optimization. MALDI-TOF MS has shown promising results in identifying cultured colonies and rapidly detecting samples. MALDI-
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Oluwatosin Ogundairo, Oluwatoyin Ayo-Farai, Chinedu Paschal Maduka, Chiamaka Chinaemelum Okongwu, Abdulraheem Olaide Babarinde, and Olamide Tolulope Sodamade. "REVIEW ON MALDI MASS SPECTROMETRY AND ITS APPLICATION IN CLINICAL RESEARCH." International Medical Science Research Journal 3, no. 3 (2023): 108–26. http://dx.doi.org/10.51594/imsrj.v3i3.642.

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Mass spectrometry has emerged as a powerful analytical tool in various scientific disciplines, and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) has gained significant prominence, particularly in the field of clinical research. This review provides a comprehensive overview of MALDI-MS, its principles, and its applications in clinical research settings. This study delves into the technical aspects of MALDI-MS, discussing key components such as the matrix, sample preparation methods, and mass analyzers. It highlights recent advancements and innovations in MALDI-MS tech
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Madhavan, Anitha, Arun Sachu, Nandini Sethuraman, Anil Kumar, and Jayalakshmi Vasudevapanicker. "Evaluation of Matrix-assisted laser desorption/ionization Time-of flight Mass spectrometry (MALDI TOF MS) and VITEK 2 in routine microbial identification." Ghana Medical Journal 55, no. 4 (2021): 308–10. http://dx.doi.org/10.4314/gmj.v55i4.12.

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Background: Microbial Identification was done by phenotypic methods. VITEK-2 and Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) are now being increasingly used in laboratories.Objectives: To compare and evaluate the usefulness of MALDI-TOF MS and VITEK-2 in routine microbial identification.Methods: The performances of MALDI-TOF MS and VITEK 2 were compared for identifying microorganisms.Results: MALDI- TOF MS and VITEK-2 correctly identified 96 % (96/100) and 97% (97/100) of the isolates upto the genus level.Conclusion: MALDI TOF MS and VITEK -2 gav
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Tesi sul tema "MALDI"

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Rodrigues, Lívia Riberti 1988. "Análise de impurezas de formas farmacêuticas sólidas por MALDI Mass Spectrometry Imaging (MALDI-MSI)." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312437.

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Orientador: Rodrigo Ramos Catharino<br>Texto em português e inglês<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-25T05:33:49Z (GMT). No. of bitstreams: 1 Rodrigues_LiviaRiberti_M.pdf: 1203619 bytes, checksum: a17baf81fa013532bd6c9d451b2336f2 (MD5) Previous issue date: 2014<br>Resumo: Atualmente, as doenças cardiovasculares constituem uma das primeiras causas de mortes no Brasil e no mundo. Neste cenário, as estatinas constituem uma notável classe de medicamentos redutores de colesterol e têm sido associadas
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Lai-Rowcroft, Lindsay Ling Gi. "Novel surfaces for MALDI-MS." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/novel-surfaces-for-maldims(331dd97a-881e-4ed0-908f-d5947f3ebeba).html.

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Matrix assisted laser desorption/ionisation mass spectrometry (MALDI-MS) for small molecule analysis has been plagued with inherent problems associated with matrix interference. The matrix plays an important role in MALDI-MS where it has the ability to absorb UV energy from the laser employed and transfer it to the analyte, acts as a proton donor and protecting the analytes from being obliterated. For decades, research has been performed to eradicate matrix interference by matrix avoidance, finding alternative matrices, suppression through sample preparation methods and via chemical modificati
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Tandina, Fatalmoudou. "Mise au point et application de technologies innovantes pour l'étude des moustiques, de leur préférence trophique et de leur microbiote." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0277/document.

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Les moustiques sont les principaux vecteurs incriminés dans la transmission d’agents pathogènes à l’homme. L’identification précise des espèces de moustiques est importante pour distinguer les espèces vectrices des non vectrices. La détermination de l’origine du repas sanguin des moustiques vecteurs est indispensable dans la compréhension du comportement des espèces vectrices. Nous avons mise à jour la littérature actuelle sur la faune Culicidienne du Mali. Ainsi, nous avons listé 106 espèces de moustiques actuellement enregistrée au Mali dont 28 Anophelinae et 78 Culicinae. Nous avons ensuite
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Krüger, Ralf. "Untersuchungen zum Einbau von Analytionen in MALDI-Matrizes sowie zur Ionisation und Adduktbildung in der MALDI-Massenspektrometrie." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969681682.

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Kirmess, Kristopher Michael. "Investigation of Primary Ion Formation Mechanisms in UV-MALDI-MS Using Excited State Dynamics of Common MALDI Matrices." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1110.

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The motivation of this dissertation is to provide insight towards primary ionization mechanisms within MALDI mass spectrometry. Albeit MALDI-MS is an extensively used analytical technique, the mechanism in which primary ions are created is still under scrutiny. Two current models of primary ionization exist which claim to elucidate the ion formation mechanisms within MALDI. In this work, excited state dynamics of MALDI matrices are shown to play an important role in the ionization mechanism. Upon inspection of the thermodynamic properties of commonly used MALDI matrices, no correlation was
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Collazo, Verena. "Reverse Sanger-Sequenzierung mittels MALDI-TOF-Massenspektrometrie." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964226871.

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Enebro, Jonas. "Characterization of carboxymethyl cellulose by MALDI-TOFMS /." Stockholm : [Fiber och polymerteknologi, Kungliga Tekniska högskolan], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4376.

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Leander, Ellinor. "Artidentifiering av mögelsvamp med MALDI-TOF MS." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-80166.

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Snabb och korrekt artidentifiering är avgörande för effektiv behandling av svampinfektioner, särskilt bland immunsupprimerade patienter. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) används rutinmässigt på kliniska laboratorier för identifiering av karaktäristiska proteinmönster hos bakterier och jästsvampar genom tolkning av proteinspektra i en masspektradatabas för korrekt artidentifiering. Mögelsvamparnas hårda cellvägg och heterogena växtsätt med varierande proteinuttryck beroende på mognadsstadie, försvårar identifiering med MALDI-TOF MS. Met
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Stauber, Jonathan. "Imagerie MALDI : nouveaux développements et applications cliniques." Lille 1, 2007. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/2007/50376-2007-379.pdf.

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Les avancées de la biologie moléculaire se sont également réalisées avec l’évolution des techniques d’imagerie dans les domaines de la génomique. La transcriptomique et plus récemment de la protéomique grâce ù l'essor d'un outil essentiel, la spectrométrie de masse. Cette technique a trouvé sa place pour générer des profils protéiques caractéristiques de l'état physiologique de la cellule, de fluides complexes tels que le sang ou les urines. Elle apparaît aujourd'hui comme un outil indissociable de la recherche en biologie et en médecine. Les nouveaux développements tendent à conduire la spect
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Jacksén, Johan. "Improved techniques for CE-MALDI-MS off-line coupling and MALDI-MS analysis of primarily hydrophobic proteins and peptides." Licentiate thesis, KTH, Chemistry, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4599.

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<p>Due to the hydrophobic nature of integral membrane proteins (IMP) they give rise to several difficulties concerning handling and analysis, which is not the case for the most water soluble proteins. New analysis methods are needed, where the insolubility problems of the hydrophobic proteins due to aggregation and adhesion are tackled. Those problems also affect digestion performance and equipment compatibility for the analysis.</p><p>Protocols for analysis and separation specified for IMP are presented in <b>Paper I</b> and<b> III</b>.</p><p>The instrumentation used in this work was capillar
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Libri sul tema "MALDI"

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Hillenkamp, Franz, and Jasna Peter-Katalinic, eds. MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.

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Porta Siegel, Tiffany, ed. MALDI Mass Spectrometry Imaging. Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839165191.

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Cole, Richard B., ed. Electrospray and MALDI Mass Spectrometry. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470588901.

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Cai, Zongwei, and Shuying Liu, eds. Applications of MALDI-TOF Spectroscopy. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35665-0.

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Hosseini, Samira, and Sergio O. Martinez-Chapa. Fundamentals of MALDI-ToF-MS Analysis. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-2356-9.

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Li, Liang, ed. Maldi Mass Spectrometry for Synthetic Polymer Analysis. John Wiley & Sons, Inc., 2009. http://dx.doi.org/10.1002/9780470567234.

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Pasch, Harald, and Wolfgang Schrepp. MALDI-TOF Mass Spectrometry of Synthetic Polymers. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05046-0.

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Pasch, Harald. MALDI-TOF Mass Spectrometry of Synthetic Polymers. Springer Berlin Heidelberg, 2003.

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Liang, Li, ed. MALDI mass spectrometry for synthetic polymers analysis. Wiley, 2010.

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Shah, Haroun N., and Saheer E. Gharbia, eds. MALDI-TOF and Tandem MS for Clinical Microbiology. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118960226.

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Capitoli di libri sul tema "MALDI"

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Morgan, Michael M., MacDonald J. Christie, Thomas Steckler, et al. "MALDI." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4339.

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Hillenkamp, Franz, Thorsten W. Jaskolla, and Michael Karas. "The MALDI Process and Method." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch1.

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Pham, Thang V., and Connie R. Jimenez. "Computational Analysis of High-Throughput MALDI-TOF-MS-Based Peptide Profiling." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch10.

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Kostrzewa, Markus. "Biotyping of Microorganisms." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch11.

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O'Connor, Peter B., Klaus Dreisewerd, Kerstin Strupat, and Franz Hillenkamp. "MALDI Mass Spectrometry Instrumentation." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch2.

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Hjernø, Karin, and Ole N. Jensen. "MALDI-MS in Protein Chemistry and Proteomics." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch3.

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Spengler, Bernhard. "MALDI-Mass Spectrometry Imaging." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch4.

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Berkenkamp, Stefan, Dirk van den Boom, and Daniele Fabris. "Analysis of Nucleic Acids, and Practical Implementations in Genomics and Genetics." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch5.

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Perreault, Hélène, Erika Lattová, Dijana Šagi, and Jasna Peter-Katalinic. "MALDI-MS of Glycans and Glycoconjugates." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch6.

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Schiller, Jürgen, and Beate Fuchs. "Lipids." In MALDI MS. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527335961.ch7.

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Atti di convegni sul tema "MALDI"

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Murray, Kermit K., Michelle D. Beeson, and David H. Russell. "Laser Ionization of Biomolecules in Solution." In Laser Applications to Chemical Analysis. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/laca.1994.tha.5.

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Many powerful laser based methods are unavailable for the analysis of molecules in solution. Techniques for the analysis of liquids are particularly important for the study of biomolecules, whose natural environment is a water solution. Mass spectrometry is a powerful analytical technique, but liquids and mass spectrometers are fundamentally incompatible. We have developed a technique for laser ionization of biomolecules in solution by applying matrix-assisted laser desorption ionization (MALDI) to liquid aerosols. In the typical MALDI experiment, the analyte biomolecule is deposited from solu
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Kinsel, Gary R., Kent Gillig, Ricky Edmondson, and David H. Russell. "Fundamental Investigations of the Mechanism of Laser Desorption and Ionization in Matrix Assisted Laser Desorption / Ionization." In Laser Applications to Chemical Analysis. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/laca.1994.thb.1.

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The recent development of Matrix Assisted Laser Desorption / Ionization (MALDI) has sparked a revolution in the field of high molecular weight mass spectrometry.1 Time-of-flight (TOF) mass spectra of proteins weighing up to 300,000 Da are now routinely produced and this achievement has fostered a variety of bioanalytical applications which were previously unapproachable using conventional mass spectrometric techniques. These successful applications have burgeoned in spite of a poor understanding of the mechanism of analyte desorption and ionization under MALDI conditions. An improved understan
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Puapaiboon, Uraiwan, Jaran Jai-nhuknan, and James A. Cowan. "Exonuclease reactivity using MALDI-TOF mass spectrometry." In BiOS 2000 The International Symposium on Biomedical Optics, edited by Darryl J. Bornhop and Kai Licha. SPIE, 2000. http://dx.doi.org/10.1117/12.384247.

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Ding, Li, Eizoh Kawatoh, Koichi Tanaka, Alan J. Smith, and Sumio Kumashiro. "High-efficiency MALDI-QIT-ToF mass spectrometer." In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, edited by Eric Munro. SPIE, 1999. http://dx.doi.org/10.1117/12.370125.

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SILVA, J. A. DA, L. NAGY, and L. G. AGUIAR. "CARACTERIZAÇÃO DE POLIÓIS INDUSTRIAIS POR MALDI-TOF." In Congresso Brasileiro de Engenharia Química em Iniciação Científica. Editora Blucher, 2017. http://dx.doi.org/10.5151/chemeng-cobeqic2017-312.

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NAOMI TAMI, MARIANA, RODRIGO RAMOS CATHARINO, and DIOGO N. OLIVEIRA. "Avaliação de corantes alimentares por MALDI-Imaging." In XXIV Congresso de Iniciação Científica da UNICAMP - 2016. Galoa, 2016. http://dx.doi.org/10.19146/pibic-2016-50969.

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Aguiar, Paula Augusta Dias Fogaça de. "Caracterização de Candida spp. isoladas da corrente sanguínea em um hospital de referência no Brasil: o uso de MALDI-TOF/MS para identificar espécies incomuns de Candida." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.10212.

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Objetivo: Candidemia é um problema de saúde com alta taxa de mortalidade. C. albicans é a espécie mais frequentemente encontrada; no entanto, espécies não albicans (CNA) têm sido cada vez mais frequentes, e essas espécies são associadas à maior resistência aos antifúngicos. As metodologias tradicionais para identificação de leveduras não são capazes de identificar corretamente todas as espécies; além disso, casos de identificação incorreta também foram relatados. Sendo assim, a utilização do MALDI-TOF/MS aprimorou a identificação de leveduras em laboratórios clínicos. O objetivo deste estudo f
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Waśko, Joanna, Aleksandra Ryk, Wojciech Fendler, and Beata Kolesińska. "Application of the MALDI-MS and MALDI-IMS in the identification of the GPR146 receptor in tissue preparations." In 37th European Peptide Symposium. The European Peptide Society, 2024. http://dx.doi.org/10.17952/37eps.2024.p1272.

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Jabbour, Rabih, Ashish Tripathi, Erik D. Emmons, et al. "Advancements in MOF characterization for enhanced MALDI sensing." In Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XIX, edited by Augustus W. Fountain, Jason A. Guicheteau, and Chris R. Howle. SPIE, 2018. http://dx.doi.org/10.1117/12.2303501.

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Kolibal, J., and D. Howard. "Novel Algorithm for MALDI-TOF Baseline Drift Removal." In 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology. IEEE, 2005. http://dx.doi.org/10.1109/cibcb.2005.1594946.

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Rapporti di organizzazioni sul tema "MALDI"

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Waite, J. H. Direct Analysis of Marine Interfaces: Mussels and MALDI. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada397968.

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Gillman, Amelie R. Correlating MALDI and MRI Biomarkers of Breast Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada540714.

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Wahl, Karen L., Kristin H. Jarman, Nancy B. Valentine, et al. Analysis of Hazardous Biological Materials by MALDI Mass Spectrometry. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/15002705.

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Samaraweera, Himali, Sun Hee Moon, and Dong U. Ahn. Characterization of Phosvitin Phosphopeptides using MALDI-TOF Mass Spectrometry. Iowa State University, 2016. http://dx.doi.org/10.31274/ans_air-180814-1389.

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KL Wahl, KH Jarman, NB Valentine, et al. Analysis of hazardous biological material by MALDI mass spectrometry. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/752459.

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Puretzky, A. A., and D. B. Geohegan. LIF-imaging and gas-phase diagnostics of laser desorbed MALDI-matrix plumes. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/563317.

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Feenstra, Adam D. Technological Development of High-Performance MALDI Mass Spectrometry Imaging for the Study of Metabolic Biology. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1409181.

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Korte, Andrew R. Development of matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) for plant metabolite analysis. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1226566.

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Sriram, Subramaniam. MALDI/Mass Spectrometry of Normal Appearing and Dystrophic Axons in Spinal Cord of Multiple Sclerosis (MS). Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada582356.

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Sriram, Subramaniam. MALDI/Mass Spectrometry of Normal Appearing" and Dystrophic Axons in Spinal Cord of Multiple Sclerosis (MS)". Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada592436.

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