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1

Dyubko, Tetiana, Vasyl Pivovarenko, Valentina Chekanova, et al. "Study of Interaction of Glycerol Cryoprotectant and Its Derivatives with Dimethylacetamide in Aqueous Solution Using Fluorescent Probes." Problems of Cryobiology and Cryomedicine 31, no. 2 (2021): 139–50. http://dx.doi.org/10.15407/cryo31.02.139.

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In this paper we have studied the interaction of the mixtures of glycerol (GL) and its oxyethylated derivatives (OEG) with polymerization degree n = 3, 25 and 30 with dimethylacetamide (DMAc) in aqueous solution using 3-hydroxy-4´-(N, N dimethylaminoflavone) fluorescent probe. The combination of GL and its oxyethylated derivatives with DMAc was found to reduce the membranotropy of certain cryoprotective agents, forming a mixture. The combination of both GL and its low molecular weight derivative (OEGn=3) with DMAc reduced the membranotropy of the latter. At the same time, combining GL derivati
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2

Kasian, N. A., V. A. Pashynska, O. V. Vashchenko, et al. "Probing of the combined effect of bisquaternary ammonium antimicrobial agents and acetylsalicylic acid on model phospholipid membranes: differential scanning calorimetry and mass spectrometry studies." Mol. BioSyst. 10, no. 12 (2014): 3155–62. http://dx.doi.org/10.1039/c4mb00420e.

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Guarnieri, Daniela, Pietro Melone, Mauro Moglianetti, Roberto Marotta, Paolo A. Netti, and Pier Paolo Pompa. "Particle size affects the cytosolic delivery of membranotropic peptide-functionalized platinum nanozymes." Nanoscale 9, no. 31 (2017): 11288–96. http://dx.doi.org/10.1039/c7nr02350b.

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Vislobokov, A. I., Yu D. Ignatov, and K. N. Melnikov. "Membranotropic action of pharmacological agents." Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology 3, no. 3 (2009): 340. http://dx.doi.org/10.1134/s1990747809030507.

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Falanga, Annarita, Massimiliano Galdiero, Giancarlo Morelli, and Stefania Galdiero. "Membranotropic peptides mediating viral entry." Peptide Science 110, no. 5 (2018): e24040. http://dx.doi.org/10.1002/pep2.24040.

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6

Galdiero, Stefania, Mariateresa Vitiello, Annarita Falanga, Marco Cantisani, Novella Incoronato, and Massimiliano Galdiero. "Intracellular Delivery: Exploiting Viral Membranotropic Peptides." Current Drug Metabolism 13, no. 1 (2012): 93–104. http://dx.doi.org/10.2174/138920012798356961.

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7

Ayvazyan, Naira M. "Membranotropic properties of Viperidae snake venoms." Toxicon 158 (February 2019): S8. http://dx.doi.org/10.1016/j.toxicon.2018.10.035.

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8

Falanga, Annarita, Massimiliano Galdiero, and Stefania Galdiero. "Membranotropic Cell Penetrating Peptides: The Outstanding Journey." International Journal of Molecular Sciences 16, no. 10 (2015): 25323–37. http://dx.doi.org/10.3390/ijms161025323.

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9

Sukhodub, A. L. "Benzene membranotropic action in rat liver microsomes." Biopolymers and Cell 12, no. 6 (1996): 116–19. http://dx.doi.org/10.7124/bc.00045e.

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10

Babusenko, E. S., G. I. El'-Registan, N. B. Gradova, A. N. Kozlova, and G. A. Osipov. "Membranotropic autoregulatory factors in methane oxidising bacteria." Russian Chemical Reviews 60, no. 11 (1991): 1221–27. http://dx.doi.org/10.1070/rc1991v060n11abeh001140.

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11

Sokolova, S. M., G. N. Buzuk, M. Ya Lovkova, and Yu V. Tyutekin. "Membranotropic Compounds and Alkaloid Accumulation in Plants." Doklady Biochemistry and Biophysics 402, no. 1-6 (2005): 220–22. http://dx.doi.org/10.1007/s10628-005-0075-x.

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12

Villalaín, José, C. Reyes Mateo, Francisco J. Aranda, Stuart Shapiro, and Vicente Micol. "Membranotropic Effects of the Antibacterial Agent Triclosan." Archives of Biochemistry and Biophysics 390, no. 1 (2001): 128–36. http://dx.doi.org/10.1006/abbi.2001.2356.

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13

Panda, Gayatree, Sabyasachi Dash, and Santosh Kumar Sahu. "Harnessing the Role of Bacterial Plasma Membrane Modifications for the Development of Sustainable Membranotropic Phytotherapeutics." Membranes 12, no. 10 (2022): 914. http://dx.doi.org/10.3390/membranes12100914.

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Abstract (sommario):
Membrane-targeted molecules such as cationic antimicrobial peptides (CAMPs) are amongst the most advanced group of antibiotics used against drug-resistant bacteria due to their conserved and accessible targets. However, multi-drug-resistant bacteria alter their plasma membrane (PM) lipids, such as lipopolysaccharides (LPS) and phospholipids (PLs), to evade membrane-targeted antibiotics. Investigations reveal that in addition to LPS, the varying composition and spatiotemporal organization of PLs in the bacterial PM are currently being explored as novel drug targets. Additionally, PM proteins su
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14

Nemésio, Henrique, and José Villalaín. "Membranotropic Regions of the Dengue Virus prM Protein." Biochemistry 53, no. 32 (2014): 5280–89. http://dx.doi.org/10.1021/bi500724k.

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15

Poralo, I. V., G. V. Ostrovskaya, and V. K. Rybal'chenko. "Membranotropic properties of cardiotonic drugs, suphan and maglucord." Neurophysiology 32, no. 3 (2000): 230–31. http://dx.doi.org/10.1007/bf02506591.

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16

Dubinin, Mikhail V., Vyacheslav A. Sharapov, Alena A. Semenova, et al. "Effect of Modified Levopimaric Acid Diene Adducts on Mitochondrial and Liposome Membranes." Membranes 12, no. 9 (2022): 866. http://dx.doi.org/10.3390/membranes12090866.

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Abstract (sommario):
This paper demonstrates the membranotropic effect of modified levopimaric acid diene adducts on liver mitochondria and lecithin liposomes. We found that the derivatives dose-dependently reduced the efficiency of oxidative phosphorylation of mitochondria due to inhibition of the activity of complexes III and IV of the respiratory chain and protonophore action. This was accompanied by a decrease in the membrane potential in the case of organelle energization both by glutamate/malate (complex I substrates) and succinate (complex II substrate). Compounds 1 and 2 reduced the generation of H2O2 by m
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17

Potemkin, V. A., M. A. Grishina, O. V. Fedorova, G. L. Rusinov, I. G. Ovchinnikova, and R. I. Ishmetova. "Theoretical Investigation of the Antituberculous Activity of Membranotropic Podands." Pharmaceutical Chemistry Journal 37, no. 9 (2003): 468–72. http://dx.doi.org/10.1023/b:phac.0000008246.07413.d9.

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18

BEAUGÉ, FRANÇOISE. "Membranotropic Effects of Ethanol Related to Tolerance and Dependence." Annals of the New York Academy of Sciences 625, no. 1 Molecular and (1991): 548–50. http://dx.doi.org/10.1111/j.1749-6632.1991.tb33887.x.

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19

Trikash, I. O., Ya T. Terletskaya, L. I. Kolchinskaya, and M. K. Malysheva. "Membranotropic properties of latrotoxin-like protein: Studies on liposomes." Neurophysiology 30, no. 2 (1998): 72–75. http://dx.doi.org/10.1007/bf02463054.

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20

Nemésio, Henrique, Francis Palomares-Jerez, and José Villalaín. "NS4A and NS4B proteins from dengue virus: Membranotropic regions." Biochimica et Biophysica Acta (BBA) - Biomembranes 1818, no. 11 (2012): 2818–30. http://dx.doi.org/10.1016/j.bbamem.2012.06.022.

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21

Yurin, V. M., G. D. Matusov, Ya F. Freimanis, V. V. Kudryashova, and K. I. Dikovskaya. "Surface activity and membranotropic action of 11-deoxyprostaglandins E1." Pharmaceutical Chemistry Journal 20, no. 9 (1986): 604–8. http://dx.doi.org/10.1007/bf01148630.

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22

Markova, M. V., I. V. Tatarinova, O. A. Tarasova, K. A. Apatrsin, V. V. Kireeva, and B. A. Trofimov. "Cationic copolymerisation of cholesterol vinyl ether with N-allenylpyrrolidone; a route to pharmacologically promising oligomers." Доклады Академии наук 485, no. 6 (2019): 697–700. http://dx.doi.org/10.31857/s0869-56524856697-700.

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Abstract (sommario):
Cationic copolymerization of cholesterol vinyl ether with N-allenylpyrrolidone yielded co-oligomers with molecular mass of 1200-2100. The polymerization of N-allenylpyrrolidone involves both 1,2- and 2,3-positions of the allenyl substituent to give four types of units as a result of prototropic isomerization of the initially formed structures. In the developed method, the composition of co-oligomers can be controlled and, hence, their hydrophilic/hydrophobic balance, solubility, and membranotropic properties can also be controlled to change the potential biological activity of the products.
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23

Safronova, Victoria N., Pavel V. Panteleev, Stanislav V. Sukhanov, Ilia Y. Toropygin, Ilia A. Bolosov та Tatiana V. Ovchinnikova. "Mechanism of Action and Therapeutic Potential of the β-Hairpin Antimicrobial Peptide Capitellacin from the Marine Polychaeta Capitella teleta". Marine Drugs 20, № 3 (2022): 167. http://dx.doi.org/10.3390/md20030167.

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Among the most potent and proteolytically resistant antimicrobial peptides (AMPs) of animal origin are molecules forming a β-hairpin structure stabilized by disulfide bonds. In this study, we investigated the mechanism of action and therapeutic potential of the β-hairpin AMP from the marine polychaeta Capitella teleta, named capitellacin. The peptide exhibits a low cytotoxicity toward mammalian cells and a pronounced activity against a wide range of bacterial pathogens including multi-resistant bacteria, but the mechanism of its antibacterial action is still obscure. In view of this, we obtain
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24

Mirgorodskaya, Alla B., Farida G. Valeeva, Dinar R. Gabdrakhmanov, et al. "Novel quinoxaline derivative: Solubilization by surfactant solutions and membranotropic properties." Tetrahedron 73, no. 34 (2017): 5115–21. http://dx.doi.org/10.1016/j.tet.2017.07.002.

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25

Eremeev, S. A., K. A. Motovilov, E. M. Volkov, and L. S. Yaguzhinsky. "SkQ3: The new member of the class of membranotropic uncouplers." Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology 5, no. 4 (2011): 310–15. http://dx.doi.org/10.1134/s1990747811050047.

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26

Faingol’d, I. I., D. A. Poletaeva, R. A. Kotelnikova, et al. "Membranotropic and relaxation properties of water-soluble gadolinium endometallofullerene derivatives." Russian Chemical Bulletin 63, no. 5 (2014): 1107–12. http://dx.doi.org/10.1007/s11172-014-0556-0.

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27

Pavlova, M., A. Serbin, N. Fedorova, E. Karaseva, E. Klimova, and A. Kushch. "Anti-cytomegalovirus Activity of Membranotropic Polyacidic Agents Effects In Vitro." Antiviral Research 82, no. 2 (2009): A50—A51. http://dx.doi.org/10.1016/j.antiviral.2009.02.115.

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28

Azouzi, Slim, Karim El Kirat, and Sandrine Morandat. "Hematin loses its membranotropic activity upon oligomerization into malaria pigment." Biochimica et Biophysica Acta (BBA) - Biomembranes 1848, no. 11 (2015): 2952–59. http://dx.doi.org/10.1016/j.bbamem.2015.08.010.

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29

Kalinovych, Viacheslav, and Volodymyr Berest. "Similarity of Gramicidin S and Cryoprotectant Polyethylene Glycol Membranotropic Effects." Problems of Cryobiology and Cryomedicine 29, no. 2 (2019): 161. http://dx.doi.org/10.15407/cryo29.02.161.

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30

Spasov, A. A., V. V. Nedogoda, O. V. Ostrovskii, and Kuame Konan. "Membranotropic effect of low-intensity laser radiation of the blood." Bulletin of Experimental Biology and Medicine 126, no. 4 (1998): 1010–13. http://dx.doi.org/10.1007/bf02447306.

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31

Vashchenko, O. V. "Model lipid bilayers as sensor bionanomaterials for characterization of membranotropic action of water-soluble substances." Functional materials 25, no. 3 (2018): 422–31. http://dx.doi.org/10.15407/fm25.03.422.

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32

Roman’ko, M. Y. "Biochemical markers of safety of nano-particles of metals on the model of isolated subcultural fractions of eukaryotes." Regulatory Mechanisms in Biosystems 8, no. 4 (2017): 564–68. http://dx.doi.org/10.15421/021787.

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Unique sizes and a high level of bioavailability allow nanoparticles of metals (NPMe) to come into direct contact with biological systems, with infectious agents, toxins, as well as with different chemical compounds and separate cell structures (proteins, lipids, nucleic acids). Other biological effects, including less toxicity than in microscopic substances, require attention to be paid to the study of the potential risk of using nanoparticles of each type in a particular way, therefore scientific support is absolutely necessary in this direction. It is believed that the cytotoxicity of nanom
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33

Makhmutov, B. B., B. S. Abdrasilov, and Yu A. Kim. "ANTIRADICAL AND MEMBRANOTROPIC ACTIONS OF QUERCETIN AND ITS COMPLEX WITH ALUMINUM." International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований), no. 7 2022 (2022): 83–88. http://dx.doi.org/10.17513/mjpfi.13417.

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34

Ivanova, Tetiana. "EFFECTS OF MEMBRANOTROPIC MICROFERTILIZERS TO GROW THE MYCELIUM OF LENTINULA EDODES." Journal of Microbiology, Biotechnology and Food Sciences 9, no. 3 (2019): 605–9. http://dx.doi.org/10.15414/jmbfs.2019/20.9.3.605-609.

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35

Kuyukina, M. S., O. A. Kochina, S. V. Gein, I. B. Ivshina, and V. A. Chereshnev. "Mechanisms of Immunomodulatory and Membranotropic Activity of Trehalolipid Biosurfactants (a Review)." Applied Biochemistry and Microbiology 56, no. 3 (2020): 245–55. http://dx.doi.org/10.1134/s0003683820030072.

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36

de Alteriis, E., L. Lombardi, A. Falanga, et al. "Polymicrobial antibiofilm activity of the membranotropic peptide gH625 and its analogue." Microbial Pathogenesis 125 (December 2018): 189–95. http://dx.doi.org/10.1016/j.micpath.2018.09.027.

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37

Walrant, Astrid, Sébastien Cardon, Fabienne Burlina, and Sandrine Sagan. "Membrane Crossing and Membranotropic Activity of Cell-Penetrating Peptides: Dangerous Liaisons?" Accounts of Chemical Research 50, no. 12 (2017): 2968–75. http://dx.doi.org/10.1021/acs.accounts.7b00455.

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38

Lisetski, L., O. Vashchenko, A. Tolmachev, and K. Vodolazhskiy. "Effects of membranotropic agents on mono- and multilayer structures of dipalmitoylphosphatidylcholine." European Biophysics Journal 31, no. 7 (2002): 554–58. http://dx.doi.org/10.1007/s00249-002-0244-0.

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39

Faingol’d, I. I., A. D. Lozhkin, A. V. Smolina, et al. "Membranotropic properties of fullerene-containing amphiphilic (co)polymers of N-vinylpyrrolidone." Russian Chemical Bulletin 67, no. 5 (2018): 800–805. http://dx.doi.org/10.1007/s11172-018-2140-5.

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40

Galdiero, Stefania, Annarita Falanga, Giancarlo Morelli, and Massimiliano Galdiero. "gH625: A milestone in understanding the many roles of membranotropic peptides." Biochimica et Biophysica Acta (BBA) - Biomembranes 1848, no. 1 (2015): 16–25. http://dx.doi.org/10.1016/j.bbamem.2014.10.006.

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41

Andreev, Sergei, Igor Andreev, Elena Nikolaeva, Anna Petrukhina, Vladimir Zemskov, and Mariam Vafina. "Membranotropic effects of peptides from the V3 loop of HIV-1." Letters in Peptide Science 5, no. 2-3 (1998): 63–66. http://dx.doi.org/10.1007/bf02443439.

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42

Parshina, E. Yu, L. Ya Gendel’, and A. B. Rubin. "Influence of hydrophobic properties of IKhFAN antioxidants on their membranotropic activity." Pharmaceutical Chemistry Journal 46, no. 2 (2012): 82–85. http://dx.doi.org/10.1007/s11094-012-0738-8.

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43

Semina, I. G., I. I. Semina, D. A. Faizyllin, et al. "Membranotropic effect of 2(chloroethoxy)-para-N-dimethylaminophenyl phosphinylacetyl hydrazide (CAPAH)." Bulletin of Experimental Biology and Medicine 126, no. 2 (1998): 797–99. http://dx.doi.org/10.1007/bf02446913.

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44

Purygin, P. P., A. A. Danilin, N. A. Klenova, N. V. Makarova, and I. K. Moiseev. "Synthesis and membranotropic activity of N-adamantanoylamino and N-adamantylacetylamino acids." Pharmaceutical Chemistry Journal 33, no. 3 (1999): 132–33. http://dx.doi.org/10.1007/bf02508448.

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45

Logashenko, E. B., I. L. Kuznetsova, E. I. Ryabchikova, V. V. Vlassov, and M. A. Zenkova. "Mechanism of the toxicity of the artificial ribonucleases for the different human cancer cell lines." Biomeditsinskaya Khimiya 56, no. 2 (2010): 230–43. http://dx.doi.org/10.18097/pbmc20105602230.

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Abstract (sommario):
The ability of artificial ribonucleases to cause in the concentration-dependent manner death of cancer cells has been studied. The cytotoxic activity of artificial ribonucleases is observed at rather low concentration of these compounds (10-5 М). Analysis of the mechanism of artificial ribonucleases citotoxicity revealed that compounds under the study exhibit membranotropic activity in addition to ribonucleases activity found earlier. This activity is responsible for effective penetration of these compounds inside cells. The results obtained show that artificial ribonucleases induce cell death
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46

Akhmedov, Alan A., Dmitriy N. Shurpik, Zainab R. Latypova, Rustem R. Gamirov, and Ivan I. Stoykov. "Synthetic meroterpenoids based on terpene alcohols: synthesis, self-assembly, and membranotropic properties." Butlerov Communications 63, no. 7 (2020): 11–18. http://dx.doi.org/10.37952/roi-jbc-01/20-63-7-11.

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Abstract (sommario):
Currently, targeted drug delivery is of great interest in the field of medicine. The study of compounds capable of permeating cell membranes is a major problem in this area. The synthesis of pharmacologically active compounds includes the formation of structures with various combinations of pharmacophore fragments and properties. Amphiphilic compounds tend to exhibit membranotropic activity. From this point of view, the modification of natural products, especially terpenoids, is of particular interest. Terpenoid structures are used as membrane anchors in the development of modulators for membr
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47

Kushnazarova, R. A., A. B. Mirgorodskaya, A. D. Voloshina, et al. "Dicarbamate Surfactant – Tween 80 Binary Systems: Aggregation, Antimicrobial Activity and Membranotropic Properties." Liquid Crystals and their Application 22, no. 2 (2022): 6–18. http://dx.doi.org/10.18083/lcappl.2022.2.6.

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48

Kondakova, H. K., H. O. Semko, O. V. Levytska, and V. M. Tsymbal. "State of antioxidant system in urogenital trichomoniasis and membranotropic effect of metronidazole." Dermatology and Venerology, no. 2 (June 4, 2021): 8–11. http://dx.doi.org/10.33743/2308-1066-2021-2-8-11.

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Abstract (sommario):
The objective of this work was to study the activity of glutathione peroxidase, glutathione reductase and the level of sulfhydryl groups in erythrocytes of patients with urogenital trichomoniasis and the effect of metronidazole on the degree of osmotic and peroxide resistance of erythrocytes from healthy donors. We examined 15 patients with urogenital trichomoniasis and 20 healthy volunteers. We studied native preparations, and also carried out a culture method using the Johnson-Trussel nutrient medium (CPLM) to identify Trichomona vaginalis. The activity of glutathione reductase, glutathione
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49

Bogdanov, G. N., R. A. Kotel'nikova, E. S. Frog, V. N. Shtol'ko, V. S. Romanova, and Yu N. Bubnov. "Enantiomers of the Amino Acid Derivatives of Fullerene C60Possess Stereospecific Membranotropic Properties." Doklady Biochemistry and Biophysics 396, no. 1-6 (2004): 165–67. http://dx.doi.org/10.1023/b:dobi.0000033519.39539.89.

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50

Gerasimenko, E. N., V. N. Meshchaninov, E. M. Zvezdina, U. E. Katireva, E. L. Tkachenko, and I. V. Gavrilov. "Comparative analysis of geroprophylactic efficiency and membranotropic action of various gas therapies." Advances in Gerontology 5, no. 1 (2015): 12–17. http://dx.doi.org/10.1134/s207905701501004x.

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