Letteratura scientifica selezionata sul tema "Metastasis"

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Articoli di riviste sul tema "Metastasis"

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Al-Muqbel, Kusai M. "Bone Marrow Metastasis Is an Early Stage of Bone Metastasis in Breast Cancer Detected Clinically by F18-FDG-PET/CT Imaging." BioMed Research International 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/9852632.

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Objective. To determine the value of 18F-FDG PET/CT in detection of bone marrow (BM) metastasis in breast cancer which is considered an early stage of bone metastasis. Patients and Methods. Retrospectively, breast cancer patients with bone metastasis were included. BM metastasis was considered if the lesion was PET positive/CT occult while bone metastasis was considered if the lesion was PET positive/ CT positive. BM metastases were observed sequentially on F18-FDG PET/CT. Results. We included 35 patients. Eighteen patients (51%) had BM metastases in addition to other bone metastases. BM metas
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Rajae, Elaouni, Moutei Hassan, Bennis Ahmed, Chraibi Fouad, Abdellaoui Meriem, and Benatiya Andaloussi Idriss. "Unusual Case of Secondary Glaucoma: Uveal Metastasis from Breast Cancer." Scholars Journal of Medical Case Reports 13, no. 03 (2025): 378–82. https://doi.org/10.36347/sjmcr.2025.v13i03.010.

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Introduction: Uveal metastasis is the most common form of intraocular malignancy. Most uveal metastais occur in the posterior uvea, and iris metastasis are relatively rare. They may present as stromal nodules or ill-defined iris thickening, or they may be associated with atypical features such as pain or iridocyclitis. Objective and Methodes: We report the case of a 54-year-old patient whose ophthalmological examination revealed a relapse of her neoplastic disease. We emphasize the importance of a detailed medical history and a systematic general examination to establish an accurate diagnosis
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Qin, Lang, Xiangtian Yu, Chuang Xu, and Yangchen Liu. "Prognostic impact of metastatic patterns and treatment modalities on overall survival in lung squamous cell carcinoma: A population-based study." Medicine 102, no. 29 (2023): e34251. http://dx.doi.org/10.1097/md.0000000000034251.

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This study aimed to investigate the impact of distinct metastasis patterns on the overall survival (OS) of individuals diagnosed with organ metastatic lung squamous cell carcinoma (LUSC). OS was calculated using the Kaplan–Meier method, and univariate and multivariate Cox regression analyses were conducted to further assess prognostic factors. A total of 36,025 cases meeting the specified criteria were extracted from the Surveillance, Epidemiology, and End Results database. Among these patients, 30.60% (11,023/36,025) were initially diagnosed at stage IV, and 22.03% (7936/36,025) of these indi
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Fidler, Isaiah J. "Melanoma Metastasis." Cancer Control 2, no. 5 (1995): 398–404. http://dx.doi.org/10.1177/107327489500200503.

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Cancer metastasis requires a series of sequential steps, each of which is rate limiting. Neoplasms are biologically heterogeneous, and the process of metastasis is highly selective. Multiple metastases often differ in biologic characteristics and can change during the course of the disease. Clonal analysis of human melanoma suggest that systemic, physiologic signals can be recognized by neoplastic cells. Brain metastases are particularly common in patients with metastatic melanoma. The blood brain barrier does not prevent the invasion of the brain parenchyma by circulating metastatic cells, an
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Ali, Kamran, Sukki Cho, Hyo Jun Jang, Kwhanmien Kim, and Sanghoon Jheon. "Predictive Factors of Thoracic Lymph Node Metastasis Accompanying Pulmonary Metastasis from Colorectal Cancer." Thoracic and Cardiovascular Surgeon 67, no. 08 (2018): 683–87. http://dx.doi.org/10.1055/s-0038-1642602.

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Background The aim of this study was to identify the factors predicting thoracic lymph node (LN) metastases for pulmonary resection from colorectal cancer (CRC). Methods The records of 160 patients who underwent pulmonary metastasectomy for CRC were retrospectively reviewed. Clinicopathologic factors were analyzed with chi-square test or t-test and logistic regression to identify predictable factors for LN metastases. Results Sixty patients (37.5%) underwent LN dissection during pulmonary metastasectomy, and LN metastases were found in five patients. Twenty-three patients had LN recurrence amo
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Isidro, Ulysses, Liam M. O'Brien, and Ronnie Sebro. "Linear mixed-effects models for estimation of pulmonary metastasis growth rate: implications for CT surveillance in patients with sarcoma." British Journal of Radiology 93, no. 1114 (2020): 20190856. http://dx.doi.org/10.1259/bjr.20190856.

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Objectives: Sarcoma patients often undergo surveillance chest CT for detection of pulmonary metastases. No data exist on the optimal surveillance interval for chest CT. The aim of this study was to estimate pulmonary metastasis growth rate in sarcoma patients. Methods: This was a retrospective review of 95 patients with pulmonary metastases (43 patients with histologically confirmed metastases and 52 with clinically diagnosed metastases) from sarcoma treated at an academic tertiary-care center between 01 January 2000 and 01 June 2019. Age, sex, primary tumor size, grade, subtype, size and volu
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Choi, Hee Jun, Jai Min Ryu, Byung Joo Chae, et al. "Is Sentinel Lymph Node Biopsy for Breast Cancer with Cytology-Proven Axillary Metastasis Safe? A Prospective Single-Arm Study." Journal of Clinical Medicine 10, no. 20 (2021): 4754. http://dx.doi.org/10.3390/jcm10204754.

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The purpose of this study was to evaluate pathologic lymph node metastasis in breast cancer with cytology-proven axillary metastasis. This study was designed prospectively. We performed axillary lymph node dissections (ALND) after lymphatic mapping by near-infrared (NIR) fluorescence imaging with Indocyanine Green (ICG). We evaluated 72 breast cancer patients with cytology-proven axillary metastasis by curative surgery at the Samsung Medical Center between May of 2016 and December of 2017. Among the 72 patients with cytology-proven axillary metastasis, 14 of 39 patients (35.9%) with one or two
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Park, Hyung Kyu, Joungho Han, Ghee Young Kwon, Min-Kyung Yeo, and Go Eun Bae. "Patterns of Extrathoracic Metastasis in Lung Cancer Patients." Current Oncology 29, no. 11 (2022): 8794–801. http://dx.doi.org/10.3390/curroncol29110691.

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Metastasis is a major cause of death in lung cancer patients. Therefore, a deeper understanding of the metastatic mechanisms is important for developing better management strategies for lung cancer patients. This study evaluated the patterns of extrathoracic metastases in lung cancer. We retrieved data for 25,103 lung cancer patients from an institutional database and then evaluated the impacts of clinicopathologic factors on metastasis patterns. We found that 36.5% of patients had extrathoracic metastasis. Younger patients had a significantly higher extrathoracic metastasis rate in most histo
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Pisani, P., G. Angeli, M. Krengli, and F. Pia. "Renal carcinoma metastasis to the parotid gland." Journal of Laryngology & Otology 104, no. 4 (1990): 352–54. http://dx.doi.org/10.1017/s0022215100112691.

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AbstractMetastatic tumours in major salivary glands are uncommon with a higher incidence of primary sites from the head and neck. The lungs and breast are the common primary sites, while metastases from the kidney are very rarely found. The authors describe a case of renal clear-cell carcinoma with metastastis to the parotid gland. The incidence of a metastasis in the parotid gland from a primary renal carcinoma, even if rare, should not be overlooked in making a correct differential diagnosis with acinic cell carcinoma and monomorphic clear cell adenoma.
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Li, Chuang, Zhao-zhong Meng, Jian-wu Qin, and Xin-guang Qiu. "Analysis of Risk Factors of Level V Lymphatic Metastasis for Papillary Thyroid Carcinoma with pN1b." Journal of Oncology 2021 (August 18, 2021): 1–5. http://dx.doi.org/10.1155/2021/5562065.

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Objective. To explore the risk factors of level V lymphatic metastasis in papillary thyroid carcinoma (PTC) patients with pN1b. Methods. Patients were selected if they presented with a suspicious level III or IV lymph node metastasis and underwent surgery by hemi or total thyroidectomy with a lymph node dissection (levels III, IV, VI, and VII). For these patients, if frozen section showed a positive level III or IV node, then levels II and V nodes were resected. Univariate analysis was performed using the chi-square test for some factors, including age, sex, tumor location, multifocal lesions,
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Tesi sul tema "Metastasis"

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Wander, Seth A. "p27 and Metastatic Progression: Molecular Mechanisms Underlying Bone Metastasis." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/690.

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The complex PI3K/mTOR pathway regulates tumor progression via effects on cellular proliferation, apoptosis, autophagy, and motility. New drugs that inhibit the catalytic site of both PI3K and mTOR have shown promise in clinical trials. Here, we report the first use of a novel, dual PI3K/mTOR catalytic site inhibitor (PF-04691502, PF1502) in a xenograft model of breast cancer metastasis to bone. Metastatic MDA-MB-1833 cells showed PI3K/mTOR activation relative to parental MDA-MB-231. Low-dose PF1502 significantly impaired tumor cell motility and invasion in vitro without causing cell cycle arre
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Björndahl, Meit A. "Lymphangiogenesis and lymphatic metastasis /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-562-3/.

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Chiang, Yan Ting. "Identification of metastasis-driving genes as potential therapeutic targets/ biomarkers for metastatic prostate cancer." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/52901.

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Metastatic prostate cancer is currently incurable. Metastasis is thought to result from changes in the expression of specific metastasis-driving genes, leading to a cascade of activated downstream genes setting the metastatic process in motion. As such, metastasis-driving genes could provide effective therapeutic targets and prognostic biomarkers for improved disease management. In search of potential metastasis-driving genes, genes with elevated expression in patient-derived metastatic LTL-313H prostate cancer tissues, as distinct from non-metastatic LTL-313B tissues, were identified. Among t
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Nielsen, S. R. "Metastasis-associated macrophages orchestrate the formation of a hospitable metastatic niche in pancreatic cancer." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3007527/.

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Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with an overall 5-year survival rate < 5%, a rate that has not improved for a long time. The dismal prognosis for PDAC is part due to late detection, often at advanced stages of the disease where patients have developed distant metastases, but also due to chemotherapeutical resistance. Patients eligible for surgical resection of the pancreatic tumour has the best prognosis, but even when resection is successful, patients often relapse with distant metastases within 2 years after surgery. Macrophages promote tumourigenesi
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Yuzhalin, Arseniy. "Proteomic profiling of metastatic matrisome reveals citrullination as a marker of colorectal liver metastasis." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:2612ba4b-b311-4802-84ae-ab60472bfe02.

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Colorectal cancer is one of the most frequently occurring malignancies and a major cause of cancer death. Distant metastases in this disease most commonly develop in the liver and are often untreatable. Here, we use proteomics to characterise, qualitatively and quantitatively, extracellular matrix (ECM) from colorectal cancer liver metastases. We show that citrullination of the ECM by cancer cell derived peptidyl arginine deiminase 4 (PAD4) is important for the growth of liver metastases. Citrullination of proteins, a posttranslational conversion of arginine residues to citrulline, is well rec
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Stitzlein, Russell Neil. "The role of ezrin in osteosarcoma metastasis and its potential use in early identification of metastases." Miami University Honors Theses / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1177692826.

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Clark, S. R. "The investigation of tumour metastasis." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370241.

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Liu, Hui Ph D. Massachusetts Institute of Technology. "Identification of a novel metastasis enhancer, CDCP1, and analysis of its functions during melanoma metastasis." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/47881.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2009.<br>Includes bibliographical references.<br>Nearly 90% of cancer mortality from solid tumors is due to metastasis of malignant cells to the distant vital organs. It is now well established that a plethora of stromal cells are present within the tumor, and contribute in various ways to tumor initiation and progression, and plasma membrane proteins are the mediators for tumor-stromal communications. In this thesis, I focused on plasma membrane proteins that may contribute to tumor metastasis. I applied quantitative ma
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Onder, Tamer T. "Role of e-cadherin in tumor metastasis and discovery of compounds targeting metastasis cancer cells." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43226.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2008.<br>Includes bibliographical references.<br>The epithelial cell adhesion molecule E-cadherin is often downregulated during carcinoma progression and metastatic spread of tumors. However, the precise mechanism and molecular basis of metastasis promotion by E-cadherin loss is not completely understood. To investigate its role in metastasis, I utilized two distinct methods of E-cadherin inhibition that distinguish between E-cadherin's cell-cell adhesion and intracellular signaling functions. While the disruption of cel
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Gooding, Alex Joseph. "Characterizing a Role for the lncRNA BORG during Breast Cancer Progression and Metastasis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1528462540265762.

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Libri sul tema "Metastasis"

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Stein, Ulrike S., ed. Metastasis. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1350-4.

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Casserez, Raimundo Gómez. Metastasis. Fundación Cultural Héctor Rojas Herazo, 1988.

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Gregory, Bock, Whelan Julie, and Symposium on Metastasis (1988 : Ciba Foundation), eds. Metastasis. Wiley, 1988.

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Singh, Gurmit, and Shafaat A. Rabbani, eds. Bone Metastasis. Humana Press, 2005. http://dx.doi.org/10.1385/1592598927.

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Prodi, Giorgio, Lance A. Liotta, Pier-Luigi Lollini, Spiridione Garbisa, Sergio Gorini, and Kurt Hellmann, eds. Cancer Metastasis. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-5037-6.

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Schirrmacher, Volker, and Reinhard Schwartz-Albiez, eds. Cancer Metastasis. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74236-1.

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Lyden, David, Danny R. Welch, and Bethan Psaila, eds. Cancer Metastasis. Cambridge University Press, 2009. http://dx.doi.org/10.1017/cbo9780511976117.

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Gorelik, Elizier L., ed. Metastasis / Dissemination. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-2534-2.

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Elieser, Gorelik, ed. Metastasis/dissemination. Kluwer Academic Publishers, 1989.

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Brooks, Susan A., and Udo Schumacher. Metastasis Research Protocols. Humana Press, 2001. http://dx.doi.org/10.1385/1592591361.

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Capitoli di libri sul tema "Metastasis"

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Popper, Helmut, and Bruno Murer. "Metastasis." In Essentials of Diagnostic Pathology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-22664-0_19.

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Popper, Helmut. "Metastasis." In Pathology of Lung Disease. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50491-8_18.

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Armstrong, Carol L. "Metastasis." In Encyclopedia of Clinical Neuropsychology. Springer New York, 2011. http://dx.doi.org/10.1007/978-0-387-79948-3_129.

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Armstrong, Carol L. "Metastasis." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56782-2_129-2.

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Armstrong, Carol L. "Metastasis." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_129.

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Muschel, Ruth J. "Metastasis." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_3671-2.

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Banfalvi, Gaspar. "Metastasis." In Homeostasis - Tumor - Metastasis. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-7335-6_5.

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Brockhausen, Inka, and William Kuhns. "Metastasis." In Glycoproteins and Human Disease. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-21960-7_26.

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Davis, Barbara J. "Metastasis." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1587.

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Tu, Shi-Ming. "Metastasis." In Cancer Treatment and Research. Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-5968-3_13.

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Atti di convegni sul tema "Metastasis"

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Costa, Rafael Everton Assunção Ribeiro da, Fergus Tomás Rocha de Oliveira, Eduarda Norberto Siqueira, Ana Lúcia Nascimento Araújo, and Sabas Carlos Vieira. "CUTANEOUS AND BONE METASTASIS OF OCCULT BREAST CANCER: CASE REPORT." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2078.

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Introduction: Occult breast cancer (OBC) is defined as a metastatic carcinoma that occurs mainly in the axillary lymph nodes, derived from a primary malignant breast tumor undetectable by clinical and radiological analyses. OBC is a rare disease accounting for 0.3%–1.0% of all breast cancers, which occurs more commonly at the age of around 55 years. The OBC represents a rare event (especially with the manifestation of systemic metastases) and a major diagnostic challenge. Thus, the aim of this study was to report a case of OBC with the primary manifestation of cutaneous metastases and the subs
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Singh, Gajender, Sant Parkash Kataria, and Rajeev Sen. "Carcinoma uterine cervix metastasis to the skin: A rare case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685280.

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Introduction: Most common site of metastasis from carcinoma cervix is lung, liver, bone and brain. Cutaneous metastasis is rare occurrence in carcinoma cervix. Incidence reported ranges from 0.1 to 2%. Common morphological pattern of skin metastases are nodules, plaques and inflammatory telangiectatic lesions. Materials and Methods: A 68 years old postmenopausal female diagnosed as squamous cell carcinoma of cervix stage III B. She was given chemotherapy and radiotherapy and on regular follow up without no evidence of disease locally. After two years she presented with a sub cutaneous nodule o
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Merello, Paula Nunes, Thais Vicentine Xavier, Angela Erguy Zucatto, Jorge Villanova Biazus, and Andre Pires Souto Damin. "Metastasis of mammary carcinoma in endometrial polyp." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2053.

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Introduction: Metastases of mammary carcinomas to female genital tract organs are rare, and when present, the most common site is the ovaries (88%), followed by the vagina (6%). The estimated prevalence for uterine metastases is about 8%, with the majority occurring in the myometrium. Endometrial metastases occur in 4% of cases but are uncommon in the form of a polyp, with few cases described in the literature. Lobular tumors, although less frequent than ductal tumors in terms of overall prevalence, are the ones that most metastasize to the genital tract, accounting for about 80% of cases. Of
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Tang, Xin, and Taher Saif. "In Vitro Cancer Metastasis Induced by Mechanical Force." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93130.

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Based on the American Cancer Society’s report at 2004, after 50-year’s efforts in bio-chemical medicine development, the U.S.A. cancer mortality is 193.9 per 100,000 persons, which is not significantly reduced from that at 1950, 185.8 per 100,000 persons. One critical reason for the clinical inefficacy is that it is not identified what signals trigger the onset of metastasis. 90% of cancer deaths are caused by metastases (1–6). During metastasis, malignant cancer cells detach from the parent cancer tumor to invade new organs (5–7). Although the primary tumor can be readily removed by surgery i
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Shareef, Sarah J., Mihai Nita-Lazar, and Maria A. Kukuruzinska. "E-cadherin N-glycosylation Modulates the Strength of Adherens Junctions." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13013.

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Metastasis, the spread of cancer cells throughout the body, claims 90% of solid tumor deaths. During metastasis, cancer cells undergo discohesion. An understanding of how to control and strengthen cell adhesion through junction formation could lead to methods for decreasing metastatic tendencies.
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Moreno, Marcelo, Amauri de Oliveira, Tália Cássia Boff, Gabriela Nogueira Matschinski, and Izadora Czarnobai. "SQUAMOUS CELL CARCINOMA METASTASIS OF THE MAMMARY GLAND: CASE REPORT." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1007.

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Introduction: Primary squamous cell carcinoma (SCC) of the breast is a rare neoplasm, which represents less than 0.1% of invasive breast cancers. Therefore, it is essential to discriminate between a primary SCC and a metastatic SCC. In order to be considered a primary carcinoma of the breast, a histological examination of the lesion must show more than 90% of squamous neoplastic cells, in addition to the absence of cutaneous SCC or other anatomical sites. Extra-mammary neoplasm metastases are uncommon, representing 0.5% to 2% of breast malignancies. Metastatic SCC in the mammary gland is an un
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Kraning-Rush, Casey M., Shawn P. Carey, and Cynthia A. Reinhart-King. "Molded Collagen Microchannels for the Study of Cancer Cell Invasion." In ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icnmm2012-73093.

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Metastasis is the cause of 90% of cancer-related deaths and yet the precise mechanism of metastasis is poorly understood[1]. To metastasize, cells break free from the primary tumor, migrate through the surrounding tissue, and enter the vascular system to move to a secondary site. To migrate through the stroma, cell can both degrade the tissue and use physical force to move the tissue from its path. However, the relative roles of matrix degradation and cellular force are not well-understood. Previous work has shown that as cell move through the matrix, they create channels that other cells can
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Hoskins, Meghan H., Shile Liang, Payal Khanna, Robert F. Kunz, and Cheng Dong. "Cytokine Convection Affects Cancer Metastasis by a Shear Rate Dependent Mechanism." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192904.

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Hoskins, Meghan H., Shile Liang, Robert F. Kunz, and Cheng Dong. "Cellular Mechanics and Biology of Tumor Cell-Leukocyte Interactions in the Near Wall Region Under Shear Flow Conditions." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176376.

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Malignant melanoma has a high propensity for metastatic spread, making it the most deadly form of skin cancer. Currently, no effective treatment exists to prevent melanoma metastasis or to inhibit metastatic tumors growing in distant organs [1,2].
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Andrade, Gustavo Moreira, Leonardo Chaves de Oliveira Moraes, Diogo Casagrande Nunes de Souza, Isadora de Sousa Gomes, Marcos Vinícius Milki, and Izabela Ramos Nascimento. "Angiogenesis, heroine, or villain? The expression and significance of vascular endothelial growth factor when dealing with the prognosis of patients with breast cancer." In Brazilian Breast Cancer Symposium 2024. Mastology, 2024. http://dx.doi.org/10.29289/259453942024v34s1086.

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Objective: Vascular endothelial growth factor (VEGF) is an important signaling protein that acts in muscle and tissue regeneration and promotes angiogenesis. However, it can help spread the tumor through metastases. Therefore, the objective of this review was to evaluate the expression and significance of VEGF when dealing with the prognosis of patients with breast cancer. Methodology: We comprehensively searched the PubMed database for studies and trials that included expression of VEGF and breast cancer prognosis in their papers. Our systematic review followed the PRISMA statement guidelines
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Rapporti di organizzazioni sul tema "Metastasis"

1

Zhao, Hao, Chunhao Liu, Yanlong Li, and Xiaoyi Li. Prognostic factors for survival in differentiated thyroid cancer with pulmonary metastases: a protocol of systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0026.

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Pulmonary metastasis (PM) is the most common form of distance metastasis in differentiated thyroid cancer (DTC), which has a poor prognosis. However, the prognostic risk factors are not yet well identified and analyzed. This systematic review and meta-analysis aims to fill this blank though identifying and discussing survival prognostic risk factors systematically for DTC patients with PM. Pulmonary metastasis (PM) is the most common form of distance metastasis in differentiated thyroid cancer (DTC), which has a poor prognosis. However, the prognostic risk factors are not yet well identified a
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2

Welch, Danny R. Metastasis Genes in Breast Cancer Metastasis to Bone. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427647.

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3

Teng, Yong. Targeting Prostate Cancer Metastasis. Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ada621823.

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4

Pettaway, Curtis A. Angiogenesis Regulates Prostate Cancer Metastasis. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada398034.

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5

Wang, Weigang. Hypoxia in Invasion and Metastasis. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada485743.

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6

Massague, Joan. Dissecting and Targeting Latent Metastasis. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada605186.

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7

Keller, Evan. Novel Aptamers to Target Metastasis. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada534850.

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8

Zhang, Yan. Antibody Microchips to Study Metastasis. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada418683.

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9

Keller, Evan, and Greg Shelley. Novel Aptamers to Target Metastasis. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada569358.

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10

Pettaway, Curtis A. Angiogenesis Regulates Prostate Cancer Metastasis. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada378066.

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