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Tesi sul tema "Molecule"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

Healey, Eleanor G. "Molecular mechanisms of Repulsive Guidance Molecule signalling." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:3ba6699b-7919-47db-a58e-95970e5e8fcf.

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Abstract (sommario):

Repulsive Guidance Molecules (RGMs) control fundamental and diverse cellular processes including axon guidance, immune cell regulation and systemic iron metabolism. RGM dysfunction has been linked to diseases such as multiple sclerosis, cancer and the iron overload disorder juvenile hemochromatosis (JHH). RGMs signal by binding directly to the transmembrane receptor Neogenin (NEO1) to trigger cytoskeleton rearrangements and subsequent axon repulsion. Additionally, RGMs are important activators of the essential developmental Bone Morphogenetic Protein (BMP) signalling pathway. RGM-activated BMP

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2

Brooke, Carly. "Synthesis, characterisation and single molecule conductance measurements of organic molecules." Thesis, University of Liverpool, 2012. http://livrepository.liverpool.ac.uk/9397/.

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Abstract (sommario):

The use of single molecules to construct electronic devices is an exciting prospect, and one that has long provided a driving force for research in the area of molecular scale electronics. In order for this emerging field to advance a deep understanding of the fundamental mechanisms that govern electron conduction at the molecular level is imperative. Recent developments in areas such as scanning tunnelling microscopy, have facilitated the determination of the electrical properties of single molecules tethered between two metallic contacts. The analysis and potentially tailoring of structure-p

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3

Rajbanshi, Arbin. "Supramolecular interactions from small-molecule selectivity to molecular capsules." Diss., Manhattan, Kan. : Kansas State University, 2010. http://hdl.handle.net/2097/3879.

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4

Becker, Jan Martin. "A molecule-up approach to chiral molecular inorganic solids." Thesis, University of Warwick, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495024.

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Abstract (sommario):

Chapter One gives an overview of molecular inorganic materials. The review focuses on areas such as metallo-organic frameworks (MOFs), organometallic Prussian Blue analogues and linear chain conductors in respect of their design. classification and potential applications. There is particular reference to the scope for the synthesis of chiral materials.

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5

Lowe, P. "Molecular de-wetting phenomena in adsorbed bio-molecule layers." Thesis, Cranfield University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269544.

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6

Rajagopal, Senthil Arun. "SINGLE MOLECULE ELECTRONICS AND NANOFABRICATION OF MOLECULAR ELECTRONIC DEVICES." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1155330219.

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7

Edman, Lars. "Single molecule dynamics /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4025-8/.

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8

Szumski, Douglas Stewart. "Single molecule spintronics." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535471.

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9

Davies, Eva Melari. "Single molecule microscopy." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-173355.

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10

Kirstein, Johanna, Christophe Jung, Christian Hellriegel, and Christoph Bräuchle. "Single molecule spectroscopy." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-196553.

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11

Aubin, Sheila Marie Josée. "Single-molecule magnets /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1997. http://wwwlib.umi.com/cr/ucsd/fullcit?p9820882.

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12

Martínez, Rodríguez Luis. "Molecule and catalyst design for recognition and activation of small molecules." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/398693.

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13

Sikor, Martin. "Single-molecule fluorescence studies of Protein Folding and Molecular Chaperones." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-138521.

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14

Grätz, Fabian [Verfasser]. "Molecule-Surface Scattering with Velocity-Controlled Molecular Beams / Fabian Grätz." Berlin : Freie Universität Berlin, 2014. http://d-nb.info/1060717735/34.

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15

Ökten, Zeynep. "Single molecule mechanics and the myosin family of molecular motors." [S.l.] : [s.n.], 2006. http://www.diss.fu-berlin.de/2006/6/index.html.

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16

Palaiokostas-Avramidis, Michail. "Molecular dynamics simulations of small molecule permeation through lipid membranes." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/31859.

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Abstract (sommario):

Passive permeation through biological membranes is an important mechanism for transporting molecules and regulating the cellular content. Studying and understanding passive permeation is also extremely relevant to many industrial applications, including drug design and nanotechnology. In vivo membranes typically consist of mixtures of lamellar and nonlamellar lipids. Lamellar lipids are characterised by their tendency to form lamellar bilayer phases, which are predominant in biology. Nonlamellar lipids, when isolated, instead form non-bilayer structures such as inverse hexagonal phases. While

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17

Zhao, Xiaotao. "The synthesis and single-molecule conductance of conjugated molecular wires." Thesis, Durham University, 2014. http://etheses.dur.ac.uk/10634/.

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Abstract (sommario):

The past decades have seen the fast development of electronic devices in the industrial sector. There is increasingly rapid growth in the demand for alternative electronic building blocks to compliment, and possibly replace, the conventional silicon-based products. Electronic devices based on organic molecules, especially those based on single molecules, receive intense studies both theoretically and experimentally. In this presented work, a new family of oligo(aryleneethenylene)s (OAE)s with molecular lengths (N…N distance) of ca. 2-6 nm were designed to investigate the length dependence of c

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18

Pantos, Stefan D. "New refinement strategies for meso-molecular and small molecule crystallography." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490343.

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CRYSTALS is a well known and widely used software package for the refinement of x-ray crystallographic data and the solution of crystal structures containing small to medium size molecules in the unit cell. Its development at the Chemical Crystallography Laboratory in Oxford has been in progress for several years, initiated by J.R. Carruthers and further developed by many others most notably RW. Betteridge, R.L Cooper, K. Front, and D.J. Watkin assisted by a number of postgraduate students.

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19

Halbert, Jason Paul. "A New Chromophoric Organic Molecule Toward Improved Molecular Optoelectronic Devices." Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc177207/.

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Abstract (sommario):

The characterization of 2,3,6,7,10,11-hexabromotriphenylene, Br6TP, is presented toward its potential use as an n-type organic semiconductor and metal-free room temperature phosphor. The crystal structure shows both anisotropic two-dimensional BrBr interactions and inter-layer ?-stacking interactions. Photophysical characteristics were evaluated using solid-state photoluminescence and diffuse reflectance spectroscopies, revealing significantly red-shifted excitations in the visible region for the yellow solid material (compared to ultraviolet absorption bands for the colorless dilute solutio

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20

Peiris, Malwattage Chandramalika Rukmali. "Covalently linked molecule–electrode contacts toward robust molecular-electronics circuits." Thesis, Curtin University, 2020. http://hdl.handle.net/20.500.11937/84186.

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Abstract (sommario):

The use of molecules as active components in electronic devices is a trend in current electronics and a potential alternative to the semiconductor-based nanoelectronics. This thesis provides a step forward in terms of potential chemistries for molecular electronics on silicon. Different molecule-electrode contacts were investigated at the macro and nano-scale using electrochemical techniques and single-molecule circuits. The work also explored the potential of silicon oxide layers as alternative materials in molecular electronics, as both a static and dynamic material.

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21

Mitsari, Efstratia. "Guest-molecule dynamics and conductivity effects in carbon-based molecular solids." Doctoral thesis, Universitat Politècnica de Catalunya, 2016. http://hdl.handle.net/10803/397721.

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Abstract (sommario):

Disordered systems are abundant in everyday life and so their study is of importance from a scientific and a technological point of view. The most common non-crystalline solid phases are structural glasses (e.g. window glass), in which both translational and orientational degrees of freedom are disordered. While at low temperature (in the glass state) the disorder is static, at higher temperature a viscous state is reached, where the disorder is dynamic (as in a liquid). Other systems exist, namely molecular solids, which display different types of disorder (either static or dynamic depending

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22

Inverarity, Iain Andrew. "Marked small molecule libraries : a new approach to molecular probe design." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/14147.

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Abstract (sommario):

This thesis documents a new approach for the identification of a small biologically active molecule’s site of interaction, through the rapid synthesis of molecular probes. A marked library approach has been developed whereby a biocompatible marker is attached onto the small molecule’s molecular scaffold. This marker plays no role in the screening process itself, but facilitates the formation of a range of molecular probes from active marked library members. As an example of molecular probe formation, site selective biotinylation will be discussed in the introduction. This marked library concep

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23

Liu, Jing. "Heterocyclic small molecule peptidomimetics." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3125.

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24

Wan, Yanjun. "Simple Molecule Mercury Sensor." NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-08082008-132023/.

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Abstract (sommario):

Several molecules previously produced from a nitrile-based cascade cyclization were examined as potential mercury sensors. Various analytical parameters, including fluorescence quantum yield, UV shift, fluorescence quenching, binding constant, binding ratio, and lowest detection limit, were measured. The best mercury sensor molecule was found to be molecule 3c, which could be easily synthesized in gram quantities (3 steps, 55% overall yield). This molecule has a very high fluorescence quantum yield (Î¦ = 0.87), high sensitivity and selectivity towards mercury ion in both organic and aqueous me

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25

Lillehei, Peter Thomas. "Single molecule mechanical testing." Diss., Georgia Institute of Technology, 2001. http://hdl.handle.net/1853/31044.

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26

Cooper, James Neil. "Positron hydrogen molecule scattering." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/12240/.

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In this thesis, we present Kohn variational calculations of scattering and annihilation parameters for very low energy interactions of positrons with molecular hydrogen. Our analysis includes the first application of the Kohn method for this system in which the interelectronic potential in the molecular target is treated explicitly. All previous Kohn calculations on positron hydrogen molecule scattering have avoided this complication by the use of the method of models. The advantage of the explicit treatment over the method of models is that it allows approximate target wavefunctions of a very

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27

Phillips, Laurie James. "Molecule-inserted silicon nanogaps." Thesis, Bangor University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540412.

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28

Wadoos, Abdul. "Lysozyme-small molecule interactions." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264109.

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29

Pugh, Sara Dorothy. "Single molecule protein folding." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441320.

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30

Marsden, David Michael. "3D small-molecule microarrays." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611660.

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31

Cluzel, Philippe. "L'adn, une molecule extensible." Paris 6, 1996. http://www.theses.fr/1996PA066519.

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Abstract (sommario):

Dans la partie i, il s'agit essentiellement de l'observation sous microscope de molecules d'adn fluorescentes isolees. On decrit une transition de phase de conformation de l'adn : la molecule est etiree dans un ecoulement visqueux et adopte une forme de batonnet. Si l'on arrete l'ecoulement, la molecule relaxe par ses extremites qui changent de conformation, et adoptent une forme de pelote. Dans la partie ii on mesure, grace a un nouvel appareil (le picodynamometre), la reponse elastique d'une molecule unique d'adn quand elle estsoumise a un etirement extreme. Nous montrons qu'un fort etiremen

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32

Kirk, Sarah Ruth. "RNA-small molecule interactions /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2000. http://wwwlib.umi.com/cr/ucsd/fullcit?p9979970.

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33

Maleki, Parastoo. "Investigation of G-quadruplex and Small Molecule Interactions at the Single Molecule Level." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1543944037378098.

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34

Howle, Christopher Roy. "Decay processes of photoexcited molecules in the VUV : comparison with ion/molecule reactions." Thesis, University of Birmingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421712.

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35

Rüttinger, Steffen. "Confocal microscopy and quantitative single molecule techniques for metrology in molecular medicine." [S.l.] : [s.n.], 2006. http://opus.kobv.de/tuberlin/volltexte/2007/1434.

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36

Sikor, Martin [Verfasser]. "Single-molecule fluorescence studies of Protein Folding and Molecular Chaperones / Martin Sikor." München : Verlag Dr. Hut, 2012. http://d-nb.info/1020298650/34.

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37

Tampi, Girish. "Investigating small molecule modulators of bio-molecular interactions : an in-silico study." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/12511/.

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Abstract (sommario):

Small molecule inhibitors are commonly used to target protein targets that assist in the spread of diseases such as AIDS, cancer and deadly forms of influenza. Despite drug companies spending millions on R&D, the number of drugs that pass clinical trials is limited due to difficulties in engineering optimal non-covalent interactions. As many protein targets have the ability to rapidly evolve resistance, there is an urgent need for methods that rapidly identify effective new compounds. The thermodynamic driving force behind most biochemical reactions is known as the Gibbs free energy and it con

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38

Mowrey, Richard Carlton. "Theoretical studies of inelastic molecule-surface and resonant electron-atom and electron-molecule scattering /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu148725958026243.

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39

McHugh, Toni. "Single molecule mechanics of Kif15." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/77516/.

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Kinesin-12 is a motor protein that has a role in the processes of mitotic spindle formation and maintenance. The human Kinesin-12, Kif15, has been shown to have some functional redundancy with Eg5, a Kinesin-5 that plays key roles in the formation of the bipolar spindle and is a potential target for anti-cancer drugs. Eg5 is thought to contribute to spindle formation by cross-linking and sliding microtubules, however little is known about the mechanism of Kif15. We have used laser tweezers to investigate the mechanical properties of Kif15 compared to those of kinesin-1. We have found that Kif1

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40

O'Sullivan, Antoinette C. "Modelling of cellulose-molecule interactions." Thesis, Bangor University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296178.

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41

Pánek, Dalibor. "Developments for single molecule studies." Thesis, University of Strathclyde, 2010. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=16933.

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Single molecule fluorescence spectroscopy has attracted considerable attention over the past two decades. Measurement on a single entity provides an opportunity to avoid ensemble averaging which is always present in conventional bulk fluorescence measurements. This makes single molecule spectroscopy particularly interesting for biophysics and biochemistry where heterogeneous systems are often encountered. The general interest of this thesis is in studies of single immobilised molecules carried out at room temperature. One of t.he major issues of single molecule spectroscopy is finding a suitab

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42

Jeranko, Timo. "Photodissociation of the oxygen molecule." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492508.

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The aim of this work was to determine the distribution of photofragments of the O2 molecule in the Schumann-Runge continuum and bands, as well as their vector correlations and alignment parameters. Pontential energy curves were calculated ab initio using variational methods both in the equilibrium geometry and in the long range dissociation limit. To obtain the distribution of products, the molecule was dissociated in a molecular dynamics calculation, and the resulting vibrational wavepackets were analysed in the long range to obtain absorption cross-sections, yielding product distribution for

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43

Lu, Siran. "Single molecule kinetic isotope effect." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526483.

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44

Hanna, Thomas Mark. "Dynamics of Feshbach molecule production." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:676c8932-9c30-4776-a264-67405fe61c0c.

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The variation of a magnetic field in the vicinity of a zero-energy resonance allows highly vibrationally excited molecules (‘Feshbach molecules’) to be produced from an ultracold atomic gas. In this thesis, we study the dynamics of this process. We begin by studying the dissociation of Feshbach molecules, showing that in the limit of a sudden jump the shape of the spectrum of dissociated atoms can act as a probe of the zero-energy resonance. For some resonances, such jumps are within reach of current experiments. We also study the intermediate region between sudden jumps and asymptotically wid

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45

Boxwell, Clive. "Small molecule models of metalloproteins." Thesis, University of York, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323507.

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46

Napoleon, Raeanne L. "Understanding small molecule-protein interactions." Thesis, Boston University, 2012. https://hdl.handle.net/2144/31592.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>The binding of small molecules to a protein is among the most important phenomena in the chemistry of life; the activity and functionality of many proteins depend critically on binding small molecules. A deep

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47

Rabinovich, Daniel. "A molecule for football fans." Revista de Química, 2016. http://repositorio.pucp.edu.pe/index/handle/123456789/99465.

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Una molécula para los aficionados al fútbol (El descubrimiento de los Fullerenos y su aparición en las estampillas del Reino Unido)<br>A molecule for football fans (The discovery of fullerenes and their appearance on stamps UK)

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48

Bhasin, Deepak. "Small Molecule Inhibitors asAnticancer Agents." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1305826098.

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49

Li, Yang. "Single Molecule Spintronics and Friction." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou151561792063398.

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50

Luccarelli, James. "Small Molecule Modulators of Apoptosis." Thesis, Harvard University, 2017. http://nrs.harvard.edu/urn-3:HUL.InstRepos:32676118.

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Abstract (sommario):

Control of cell survival relies on a delicate balance between pro-apoptotic and anti-apoptotic signalling. In humans, the key regulatory proteins are those of the BCL-2 family, which include effector proteins such as BAX and BAK, anti-apoptotic proteins including BCL-2 and MCL-1, and pro-apoptotic proteins including BID and BIM. Dysregulation of apoptosis is among the Hallmarks of Cancer, and modulation of apoptosis holds promise as an effective therapeutic strategy for a range of malignancies. This thesis advances new strategies for modulating apoptosis using small molecules. The first secti

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