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Tesi sul tema "Multiple myeloma Chemotherapy"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 30 gennaio 2023

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1

Turner, Joel G. "Drug resistance to topoisomerase directed chemotherapy in human multiple myeloma." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002446.

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2

Redzepovic, Jasmina [Verfasser]. "Meta-analysis in context : Chemotherapy versus chemotherapy combined with bisphosphonate therapy in multiple myeloma patients / Jasmina Redzepovic." Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023664585/34.

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3

Viziteu, Elena. "RECQ1 Helicase Involvement in the Resistance to Replication Stress and Chemotherapy in Multiple Myeloma Myélome Multiple." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTT008.

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Abstract (sommario):

Le myélome multiple (MM) est une néoplasie B caractérisée par l’accumulation d’un clone plasmocytaire dans la moelle osseuse. Des études ont démontré que les modifications épigénétiques comme la méthylation de l’ADN jouent un rôle dans la régulation d’expression de différents gènes associés au cancer. Dans une étude récente, nous avons pu décrire un score génique de méthylation de l’ADN permettant de prédire la sensibilité des cellules de MM aux inhibiteurs de DNMT (DNA methyltranfexrase) (Moreaux, et al 2012). Parmi les gènes dont l’expression est inhibée par les inhibiteurs de DNMT et associ

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4

Pan, Beiqing. "Mechanisms of skeletal disease mediated by haematological malignancies /." Title page, table of contents and abstract only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09php1871.pdf.

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Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine and The Hanson Centre, Institute of Medical and Veterinary Science, 2004.<br>"August 2004" Errata inside front cover. Bibliography: leaves 126-159.

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5

Pan, Beiqing. "Molecular and cellular studies of zoledronic acid : a potent inhibitor of multiple myeloma-induced osteolysis." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09MSM/09msmp187.pdf.

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Bibliography: leaves 86-103. Investigates the effect of zoledronic acid on myeloma cells and osteoblast-like cells to establish the molecular and cellular mechanisms responsible for the clinical effectiveness of bisphosphonates in the treatment of patients with myelomatosis. Concludes that zoledronic acid inhibits myelomatosis-induced osteolysis thorugh the mechanisms of myeloma cell death and proliferation and maturation of osteoblasts.

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6

Nikolich‐Zugich, Tijana. "Effects of High Vs. Reduced‐Dose Melphalan For Autologous Bone Marrow Transplantation in Multiple Myeloma On Pulmonary Function: A Longitudinal Study." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/623514.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.<br>Bone marrow transplants (BMT, also hematopoietic stem cell transplants or HSCT/SCT) are one of the greatest medical achievements of the 20th century. They offer a treatment for a host of malignant and nonmalignant hematopoietic disorders, genetic diseases and solid tumors that could otherwise be fatal. Studies have found that 60% of patients undergoing BMT develop pulmonary complications (PC), and 1/3 of those require intensive care a

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7

Sezer, Orhan. "Angiogenese und Knochenstoffwechsel beim multiplen Myelom." Doctoral thesis, [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963183303.

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8

Andrews, S. W. "Genotoxicity and functionality assessment of a bone marrow stromal cell line following chemotherapy exposure in an in vitro model of multiple myeloma." Thesis, University of the West of England, Bristol, 2017. http://eprints.uwe.ac.uk/30035/.

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Abstract (sommario):

Multiple myeloma (MM) is a haematological malignancy characterized by terminally differentiated plasma cells and their accumulation in the bone marrow (BM). Despite significant advances in therapeutic strategies it currently remains incurable. The interactions between the BM microenvironment and malignant plasma cells have been pivotal to understanding this disease. Previous reports have shown that patients with a haematological malignancy sustain “damage” to their BM, but how much of this is due to the disease and/or the treatment is currently unknown. Furthermore MM plasma cells have been do

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9

Cachia, Elaine. "The involvement of the central nervous system in chemotherapy-induced peripheral neuropathy, and the symptom burden and health-related quality of life in patients with multiple myeloma." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/3885/.

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Background: Modern treatments extend life expectancy in patients with multiple myeloma (MM) and a high incidence of chemotherapy-induced peripheral neuropathy (CIPN) has evolved. The impact of disease and treatment on health-related quality of life (HRQoL) in MM is poorly characterised. This work aimed to investigate (i) the neuroanatomical functional correlates of pain processing in CIPN and (ii) HRQoL and symptom burden in advanced, intensively-treated myeloma. Methods: First study: twelve neurophysiologically assessed patients with CIPN and 12 healthy volunteers underwent fMRI to determine

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10

Strifler, Susanne [Verfasser], and Stefan [Gutachter] Knop. "Eine späte, dritte Hochdosis-Chemotherapie als wirksame Rezidivbehandlung des fortgeschrittenen multiplen Myeloms / Susanne Strifler ; Gutachter: Stefan Knop." Würzburg : Universität Würzburg, 2018. http://d-nb.info/1159881219/34.

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11

Herzog, Christine. "Prädiktiver Wert des G-CSF-stimulierten Leukozytenwertes für die Blutstammzellsammlung nach IEV-Chemotherapie bei Lymphomen und multiplem Myelom." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-28990.

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12

Neubauer, Florian [Verfasser], Roland [Akademischer Betreuer] Fenk, and Stephan [Akademischer Betreuer] Steiner. "Düsseldorfer Ergebnisse zur Hochdosis-Chemotherapie mit autologer Blutstammzelltransplantation bei Patienten mit Multiplem Myelom / Florian Neubauer. Gutachter: Roland Fenk ; Stephan Steiner." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2012. http://d-nb.info/1021218995/34.

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13

Eckhardt, Matthias [Verfasser], Alexander [Gutachter] Baraniskin, and Christian [Gutachter] Teschendorf. "Einfluss einer Bortezomib-haltigen Induktions-Therapie auf das Outcome bei Multiplen Myelom nach Hochdosis-Chemotherapie / Matthias Eckhardt ; Gutachter: Alexander Baraniskin, Christian Teschendorf ; Medizinische Fakultät." Bochum : Ruhr-Universität Bochum, 2020. http://d-nb.info/1217859632/34.

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14

Pan, Beiqing. "Mechanisms of skeletal disease mediated by haematological malignancies / Beiqing Pan." Thesis, 2004. http://hdl.handle.net/2440/22124.

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Abstract (sommario):

"August 2004"<br>Errata inside front cover.<br>Bibliography: leaves 126-159.<br>xi, 159, [12] leaves : ill., plates ; 30 cm.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine and The Hanson Centre, Institute of Medical and Veterinary Science, 2004

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15

Strifler, Susanne. "Eine späte, dritte Hochdosis-Chemotherapie als wirksame Rezidivbehandlung des fortgeschrittenen multiplen Myeloms." Doctoral thesis, 2018. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-149373.

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Abstract (sommario):

Das multiple Myelom muss trotz aller Therapierfolge in den letzten drei Jahrzehnten seit Einführung der Melphalan-basierten Hochdosistherapie mit autologer Stammzell-Transplantation als eine unheilbare maligne hämatologische Systemerkrankung angesehen werden. Trotz einer großen Anzahl vielversprechender neuer Therapieoptionen im Bereich von IMiDs, PIs und gänzlich neuer immuntherapeutischer Behandlungsansätze stellt dabei die Behandlung eines Myelom-Patienten im späten Krankheitsrezidiv nach Versagen von Lenalidomid und Bortezomib eine therapeutische Herausforderung dar. Daneben erweisen sich

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16

Winterberg, Torsten. "Klinische Parameter und deren Einfluss auf den Verlauf der primären Hochdosischemotherapie mit autologer Stammzelltransplantation beim Multiplen Myelom." Doctoral thesis, 2011. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-71203.

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Abstract (sommario):

In dieser Arbeit wurden die Daten von 90 konsekutiven Patienten mit Multiplem Myelom, welche im Zeitraum vom 11.04.2005 bis zum 08.11.2010 mit einer Hochdosischemotherapie und autologer Stammzelltransplantation in den Kliniken Essen Süd behandelt wurden, retrospektiv untersucht und statistisch ausgewertet. Es konnte gezeigt werden, dass ein gutes Ansprechen nach den Induktionstherapien mit einem guten Ansprechen sechzig Tage nach der Transplantation korreliert. Einen Zusammenhang zwischen dem initialen Ausmaß der Endorganschäden und dem Verlauf oder dem Ansprechen der Hochdosischemotherapie mi

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17

Herzog, Christine [Verfasser]. "Prädiktiver Wert des G-CSF-stimulierten Leukozytenwertes für die Blutstammzellsammlung nach IEV-Chemotherapie bei Lymphomen und multiplem Myelom / vorgelegt von Christine Herzog, geb. von Osten." 2004. http://d-nb.info/973265787/34.

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