Accedi

Bibliografie tematiche / Nitric oxide – Physiological effect / Articoli di riviste

Segui questo link per vedere altri tipi di pubblicazioni sul tema: Nitric oxide – Physiological effect.

Articoli di riviste sul tema "Nitric oxide – Physiological effect"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 febbraio 2023

Cita una fonte nei formati APA, MLA, Chicago, Harvard e in molti altri stili

Scegli il tipo di fonte:

Vedi i top-50 articoli di riviste per l'attività di ricerca sul tema "Nitric oxide – Physiological effect".

Accanto a ogni fonte nell'elenco di riferimenti c'è un pulsante "Aggiungi alla bibliografia". Premilo e genereremo automaticamente la citazione bibliografica dell'opera scelta nello stile citazionale di cui hai bisogno: APA, MLA, Harvard, Chicago, Vancouver ecc.

Puoi anche scaricare il testo completo della pubblicazione scientifica nel formato .pdf e leggere online l'abstract (il sommario) dell'opera se è presente nei metadati.

Vedi gli articoli di riviste di molte aree scientifiche e compila una bibliografia corretta.

1

Smiljic, Sonja, Vojkan Nestorovic, and Sladjana Savic. "Modulatory role of nitric oxide in cardiac performance." Medical review 67, no. 9-10 (2014): 345–52. http://dx.doi.org/10.2298/mpns1410345s.

Testo completo

Abstract (sommario):

Nitric oxide is produced by almost all cardiac cells, endothelial cells, cardiomyocytes and nerve fibers. It is synthesized by an enzyme, a nitric oxide synthase, which occurs in endothelial, neural and inducible form. The distribution of nitric oxide synthase in the heart is characterized by a pronounced non-uniformity. Nitric oxide exerts its effects in physiological and pathophysiological conditions. The physiological effects of low concentrations of nitric oxide, which is released in the normal conditions under the influence of constituent enzymes, occur via cyclic guanosine monophosphate.

Gli stili APA, Harvard, Vancouver, ISO e altri

2

Ukeri, John, Michael T. Wilson, and Brandon J. Reeder. "Modulating Nitric Oxide Dioxygenase and Nitrite Reductase of Cytoglobin through Point Mutations." Antioxidants 11, no. 9 (September 15, 2022): 1816. http://dx.doi.org/10.3390/antiox11091816.

Testo completo

Abstract (sommario):

Cytoglobin is a hexacoordinate hemoglobin with physiological roles that are not clearly understood. Previously proposed physiological functions include nitric oxide regulation, oxygen sensing, or/and protection against oxidative stress under hypoxic/ischemic conditions. Like many globins, cytoglobin rapidly consumes nitric oxide under normoxic conditions. Under hypoxia, cytoglobin generates nitric oxide, which is strongly modulated by the oxidation state of the cysteines. This gives a plausible role for this biochemistry in controlling nitric oxide homeostasis. Mutations to control specific pr

Gli stili APA, Harvard, Vancouver, ISO e altri

3

Sibgatullin, I. T., R. Ya Gilmutdinov, and T. M. Zakirov. "The Effect of the Drug Estrofan on the Content of Nitric Oxide (II), Sex Hormones, Biochemical Parameters and Their Relationship in Cows." BIO Web of Conferences 37 (2021): 00170. http://dx.doi.org/10.1051/bioconf/20213700170.

Testo completo

Abstract (sommario):

The physiological functions of nitric oxide (II) are diverse, and its therapeutic uses continue to expand. Many methods have been found to regulate the production of this compound, both physiological, regulated by the body itself, and as a result of various, drug and non-drug, external influences, correcting the ability of cells, organs and tissues to produce nitric oxide (II). The drug estrophan (synthetic prostaglandin PGF2α) has an activating effect on the nitric oxide (II) system and on sex hormones that regulate the reproductive functions of cows. The introduction of estrophan to cows is

Gli stili APA, Harvard, Vancouver, ISO e altri

4

Jovic, Slavoljub, Jelka Stevanovic, Suncica Borozan, Blagoje Dimitrijevic, Svetlana Fister, and Jelena Aleksic. "Useful and harmful effects of nitric oxide." Veterinarski glasnik 67, no. 3-4 (2013): 245–57. http://dx.doi.org/10.2298/vetgl1304245j.

Testo completo

Abstract (sommario):

In living sistems synthesis of nitric oxide occurs during metabolism from Larginin, nitrite and ascorbate. Being very significant carrier of information within numerous both physiological and pathological proceses in mammals' organisms, nitric oxid could possibly be useful as well as harmful. Nitric oxide synthesis is adjuvant in a healthy organism because it represents the basic molecule for understanding numerous processes in neurology, psychology, immunology and varios related fields. In other words, nitric oxide participate in number of physiological processes, such as: transmission of ner

Gli stili APA, Harvard, Vancouver, ISO e altri

5

Muftin, Najlaa Qassim, Asma Jameil Al-Lamei, Suzanne Jubair, Abdalla Raied Jabber, and Rasha Shakir Mahmood. "The Role Of Nitric Oxide In Cancer Development & it`s Therapy." Journal of advanced Sciences and Engineering Technologies 3, no. 1 (January 3, 2020): 21–34. http://dx.doi.org/10.32441/jaset.03.01.02.

Testo completo

Abstract (sommario):

The Nitric oxide is a free radical belongs to reactive nitrogen species, acts as a signal molecule in many physiological and pathological processes as well as plays a significant role in a variety of biological processes including its action as a regulator to programmed cell death (apoptosis). In addition to its role in tumor formation, proliferation, and metastasis, Nitric oxide has also been stated to have tumoricidal effects. Therefore this review deals with the effect of nitric oxide on different types of cancer and its use in cancer drugs

Gli stili APA, Harvard, Vancouver, ISO e altri

6

Suschek, Christoph V., Dennis Feibel, Maria von Kohout, and Christian Opländer. "Enhancement of Nitric Oxide Bioavailability by Modulation of Cutaneous Nitric Oxide Stores." Biomedicines 10, no. 9 (August 29, 2022): 2124. http://dx.doi.org/10.3390/biomedicines10092124.

Testo completo

Abstract (sommario):

The generation of nitric oxide (NO) in the skin plays a critical role in wound healing and the response to several stimuli, such as UV exposure, heat, infection, and inflammation. Furthermore, in the human body, NO is involved in vascular homeostasis and the regulation of blood pressure. Physiologically, a family of enzymes termed nitric oxide synthases (NOS) generates NO. In addition, there are many methods of non-enzymatic/NOS-independent NO generation, e.g., the reduction of NO derivates (NODs) such as nitrite, nitrate, and nitrosylated proteins under certain conditions. The skin is the lar

Gli stili APA, Harvard, Vancouver, ISO e altri

7

Suresh, Vinod, David A. Shelley, Hye-Won Shin, and Steven C. George. "Effect of heterogeneous ventilation and nitric oxide production on exhaled nitric oxide profiles." Journal of Applied Physiology 104, no. 6 (June 2008): 1743–52. http://dx.doi.org/10.1152/japplphysiol.01355.2007.

Testo completo

Abstract (sommario):

Elevated exhaled nitric oxide (NO) in the breath of asthmatic subjects is thought to be a noninvasive marker of lung inflammation. Asthma is also characterized by heterogeneous bronchoconstriction and inflammation, which impact the spatial distribution of ventilation in the lungs. Since exhaled NO arises from both airway and alveolar regions, and its level in exhaled breath depends strongly on flow, spatial heterogeneity in flow patterns and NO production may significantly affect the exhaled NO signal. To investigate the effect of these factors on exhaled NO profiles, we developed a multicompa

Gli stili APA, Harvard, Vancouver, ISO e altri

8

Cui, X. M., Y. K. Zhang, X. B. Wu, and C. S. Liu. "The investigation of the alleviated effect of copper toxicity by exogenous nitric oxide in tomato plants." Plant, Soil and Environment 56, No. 6 (June 3, 2010): 274–81. http://dx.doi.org/10.17221/98/2009-pse.

Testo completo

Abstract (sommario):

As a bioactive signal, nitric oxide (NO) is involved in multiple plant physiological responses, especially under some abiotic stress. Here, we investigated the effects of exogenous nitric oxide on both the reactive oxygen species (ROS) scavenging metabolism and regulating functions of plasma membrane and tonoplast in tomato plants treated with 50&micro;M CuCl<sub>2</sub>. Copper stress induced significant accumulation of H<sub>2</sub>O<sub>2</sub>, led to serious lipid peroxidation, and finally markedly decreased shoot height and fresh weight of tomato p

Gli stili APA, Harvard, Vancouver, ISO e altri

9

Nenasheva, N. M., and N. M. Nenasheva. "ROLE OF NITRIC OXIDE IN EXHALED AIR IN BRONCHIALASTHMA." Russian Journal of Allergy 7, no. 1 (March 15, 2010): 26–31. http://dx.doi.org/10.36691/rja871.

Testo completo

Abstract (sommario):

In this review the main physiological effects of nitric oxide in the human body have been considered, as well as its pathophysiologic role in bronchial asthma. Methods for determination of nitric oxide in exhaled air have been described. The importance of determining the level of nitric oxide in patients with bronchial asthma has been analyzed.

Gli stili APA, Harvard, Vancouver, ISO e altri

10

Satoh, Nobuhiko, Motonobu Nakamura, Atsushi Suzuki, Hiroyuki Tsukada, Shoko Horita, Masashi Suzuki, Kyoji Moriya, and George Seki. "Effects of Nitric Oxide on Renal Proximal Tubular Na+Transport." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/6871081.

Testo completo

Abstract (sommario):

Nitric oxide (NO) has a wide variety of physiological functions in the kidney. Besides the regulatory effects in intrarenal haemodynamics and glomerular microcirculation,in vivostudies reported the diuretic and natriuretic effects of NO. However, opposite results showing the stimulatory effect of NO on Na+reabsorption in the proximal tubule led to an intense debate on its physiological roles. Animal studies have showed the biphasic effect of angiotensin II (Ang II) and the overall inhibitory effect of NO on the activity of proximal tubular Na+transporters, the apical Na+/H+exchanger isoform 3,

Gli stili APA, Harvard, Vancouver, ISO e altri

11

Kharitonov, Sergei A., Gert Lubec, Barbara Lubec, Magnus Hjelm, and Peter J. Barnes. "l-Arginine Increases Exhaled Nitric Oxide in Normal Human Subjects." Clinical Science 88, no. 2 (February 1, 1995): 135–39. http://dx.doi.org/10.1042/cs0880135.

Testo completo

Abstract (sommario):

1. Endogenous nitric oxide plays an important physiological role and is synthesized by several isoforms of nitric oxide synthase from the semiessential amino acid l-arginine. Nitric oxide is detectable in the exhaled air of normal individuals and may be used to monitor the formation of nitric oxide in the respiratory tract. 2. We have investigated the effect of orally administered l-arginine (0.05, 0.1, 0.2 g/kg) compared with matched placebo on the concentration of nitric oxide in the exhaled air in 23 normal individuals. 3. l-Arginine caused significant increases in the concentration of nitr

Gli stili APA, Harvard, Vancouver, ISO e altri

12

Bautista, A. P., and J. J. Spitzer. "Inhibition of nitric oxide formation in vivo enhances superoxide release by the perfused liver." American Journal of Physiology-Gastrointestinal and Liver Physiology 266, no. 5 (May 1, 1994): G783—G788. http://dx.doi.org/10.1152/ajpgi.1994.266.5.g783.

Testo completo

Abstract (sommario):

Nitric oxide, a known scavenger of toxic oxygen-derived radicals, has been shown to have a protective effect against tissue injury in endotoxemia. Based on the hypothesis that under normal physiological conditions, a balance between superoxide and nitric oxide exists in vivo, this work examines hepatic superoxide release after nitric oxide formation is inhibited in vivo. Male Sprague-Dawley rats were treated intravenously with N omega-nitro-L-arginine methyl ester (L-NAME; 50 mg/kg body wt), an inhibitor of nitric oxide synthase. One hour later, superoxide anion release by the perfused liver w

Gli stili APA, Harvard, Vancouver, ISO e altri

13

Okudaira, Mariko, Yasuo Ontachi, Tomoe Mizutani, Mika Omote, Tomotaka Yoshida, Minori Kaneda, Masahide Yamazaki, et al. "Antithrombotic role of nitric oxide in rats under physiological conditions." Thrombosis and Haemostasis 91, no. 01 (2004): 71–75. http://dx.doi.org/10.1160/th03-05-0292.

Testo completo

Abstract (sommario):

SummaryAlthough sepsis-induced release of nitric oxide (NO) is known to have an antithrombotic effect, it is unknown if NO exerts this same effect under physiological conditions. We have therefore attempted to determine whether or not NO protects against thrombus formation in normal Wistar rats injected with various amounts (0.8, 4.0, 20.0 and 100mg/kg/4hr) of L-NAME (N (omega)-nitro-l-arginine methyl ester), an NO synthase inhibitor, via the tail vein. Plasma levels of D-dimer fragments of fibrin were significantly increased in rats receiving L-NAME (0.21±0.04, 0.22±0.05, 0.26±0.07, 0.59±0.17

Gli stili APA, Harvard, Vancouver, ISO e altri

14

Reid, MB. "Reactive Oxygen and Nitric Oxide in Skeletal Muscle." Physiology 11, no. 3 (June 1, 1996): 114–19. http://dx.doi.org/10.1152/physiologyonline.1996.11.3.114.

Testo completo

Abstract (sommario):

Skeletal muscle produces oxygen radicals, nitric oxide, and a variety of redox-active derivatives that modulate muscle function under physiological conditions. In unfatigued muscle, reactive oxygen intermediates and nitric oxide exert opposing effects on excitation-contraction coupling. During strenuous exercise, oxidants accumulate in the tissue and accelerate the fatigue process.

Gli stili APA, Harvard, Vancouver, ISO e altri

15

Lefer, Allan M., and David J. Lefer. "II. Nitric oxide protects in intestinal inflammation." American Journal of Physiology-Gastrointestinal and Liver Physiology 276, no. 3 (March 1, 1999): G572—G575. http://dx.doi.org/10.1152/ajpgi.1999.276.3.g572.

Testo completo

Abstract (sommario):

This article examines the evidence for nitric oxide (NO) as a protective agent in splanchnic ischemia-reperfusion and other forms of acute intestinal inflammation. Four major points emerge from this body of data. First, acute intestinal inflammation results in an early (i.e., <5 min) and severe decrease in endothelium-derived NO. Thus the early trigger event in this condition is a functional loss of NO. Second, administration of exogenous NO, NO donors, or NO precursors ameliorate splanchnic ischemia-reperfusion and other forms of acute intestinal inflammation (i.e., splanchnic trauma). The

Gli stili APA, Harvard, Vancouver, ISO e altri

16

Murad, Ferid. "Discovery of Some of the Biological Effects of Nitric Oxide and its Role in Cell Signaling." Bioscience Reports 19, no. 3 (June 1, 1999): 133–54. http://dx.doi.org/10.1023/a:1020265417394.

Testo completo

Abstract (sommario):

The role of nitric oxide in cellular signaling in the past 22 years has become one of the most rapidly growing areas in biology with more than 20,000 publications to date. Nitric oxide is a gas and free radical with an unshared electron that can regulate an ever-growing list of biological processes. In many instances nitric oxide mediates its biological effects by activating guanylyl cyclase and increasing cyclic GMP synthesis from GTP. However, the list of effects of nitric oxide that are independent of cyclic GMP is also growing at a rapid rate. For example, nitric oxide can interact with tr

Gli stili APA, Harvard, Vancouver, ISO e altri

17

Murad, Ferid. "Discovery of Some of the Biological Effects of Nitric Oxide and its Role in Cell Signaling." Bioscience Reports 24, no. 4-5 (August 10, 2004): 452–74. http://dx.doi.org/10.1007/s10540-005-2741-8.

Testo completo

Abstract (sommario):

The role of nitric oxide in cellular signaling in the past 22 years has become one of the most rapidly growing areas in biology with more than 20,000 publications to date. Nitric oxide is a gas and free radical with an unshared electron that can regulate an ever-growing list of biological processes. In many instances nitric oxide mediates its biological effects by activating guanylyl cyclase and increasing cyclic GMP synthesis from GTP. However, the list of effects of nitric oxide that are independent of cyclic GMP is also growing at a rapid rate. For example, nitric oxide can interact with tr

Gli stili APA, Harvard, Vancouver, ISO e altri

18

Romero, J. C., V. Lahera, M. G. Salom, and M. L. Biondi. "Role of the endothelium-dependent relaxing factor nitric oxide on renal function." Journal of the American Society of Nephrology 2, no. 9 (March 1992): 1371–87. http://dx.doi.org/10.1681/asn.v291371.

Testo completo

Abstract (sommario):

The role of nitric oxide in renal function has been assessed with pharmacologic and physiologic interventions. Pharmacologically, the renal vasodilation and, to some extent, the natriuresis produced by endothelium-dependent vasodilators such as acetylcholine and bradykinin are mediated by nitric oxide and also by prostaglandins. However, prostaglandins and nitric oxide do not participate in the renal effects produced by endothelium-independent vasodilators such as atrial natriuretic peptide, prostaglandin I2, and nitroprusside. Physiologically, nitric oxide and prostaglandins exert a strong re

Gli stili APA, Harvard, Vancouver, ISO e altri

19

Karthikesh, Madhumithra Subramanian, and Xinmai Yang. "The effect of ultrasound cavitation on endothelial cells." Experimental Biology and Medicine 246, no. 7 (January 18, 2021): 758–70. http://dx.doi.org/10.1177/1535370220982301.

Testo completo

Abstract (sommario):

Acoustic cavitation has been widely explored for both diagnostic and therapeutic purposes. Ultrasound-induced cavitation, including inertial cavitation and non-inertial cavitation, can cause microstreaming, microjet, and free radical formation. The acoustic cavitation effects on endothelial cells have been studied for drug delivery, gene therapy, and cancer therapy. Studies have demonstrated that the ultrasound-induced cavitation effect can treat cancer, ischaemia, diabetes, and cardiovascular diseases. In this minireview, we will review the impact of ultrasound-induced cavitation on the endot

Gli stili APA, Harvard, Vancouver, ISO e altri

20

Garthwaite, John. "Nitric oxide as a multimodal brain transmitter." Brain and Neuroscience Advances 2 (January 2018): 239821281881068. http://dx.doi.org/10.1177/2398212818810683.

Testo completo

Abstract (sommario):

One of the simplest molecules in existence, nitric oxide, burst into all areas of biology some 30 years ago when it was established as a major signalling molecule in the cardiovascular, nervous and immune systems. Most regions of the mammalian brain synthesise nitric oxide and it has many diverse roles both during development and in adulthood. Frequently, nitric oxide synthesis is coupled to the activation of NMDA receptors and its physiological effects are mediated by enzyme-linked receptors that generate cGMP. Generally, nitric oxide appears to operate in two main modes: first, in a near syn

Gli stili APA, Harvard, Vancouver, ISO e altri

21

Kamosinska, B., M. W. Radomski, M. Duszyk, A. Radomski, and S. F. Man. "Nitric oxide activates chloride currents in human lung epithelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 272, no. 6 (June 1, 1997): L1098—L1104. http://dx.doi.org/10.1152/ajplung.1997.272.6.l1098.

Testo completo

Abstract (sommario):

Epithelial Cl- channels are regulated by various physiological factors, including guanosine 3',5'-cyclic monophosphate (cGMP). Because cGMP mediates many of the physiological actions of nitric oxide (NO), we have studied both the presence of endogenous NO and the effects of exogenous NO on Cl- currents in A549 human lung epithelial cells. We have detected Ca(2+)-dependent NO synthase activity in A549 cells. Using the perforated patch-clamp technique, we have shown that inhibition of this enzyme by NG-monomethyl-L-arginine decreased Cl- current, an effect that was reversed by the NO donor S-nit

Gli stili APA, Harvard, Vancouver, ISO e altri

22

Akanji, Musbau A., Anne A. Adeyanju, Damilare Rotimi, and Oluyomi S. Adeyemi. "Nitric Oxide Balance in Health and Diseases: Implications for New Treatment Strategies." Open Biochemistry Journal 14, no. 1 (July 31, 2020): 25–32. http://dx.doi.org/10.2174/1874091x02014010025.

Testo completo

Abstract (sommario):

Nitric Oxide (NO) is an essential signaling molecule with diverse physiological functions in humans. The steady-state concentration and site of production of nitric oxide determine its effects in biological systems. The human cells are exposed to both beneficial and harmful effects of NO. These dual effects of NO could depend on its local concentration in the cells. Additionally, the rate of synthesis, translocation, direct interaction with other molecules, and signals contribute to the biochemical and physiological effects of NO. In this review, the biochemical and physiological role of NO, p

Gli stili APA, Harvard, Vancouver, ISO e altri

23

French, Stephanie, Cecilia Giulivi, and R. S. Balaban. "Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity." American Journal of Physiology-Heart and Circulatory Physiology 280, no. 6 (June 1, 2001): H2863—H2867. http://dx.doi.org/10.1152/ajpheart.2001.280.6.h2863.

Testo completo

Abstract (sommario):

The capacity of isolated porcine heart mitochondria to produce nitric oxide (NO) via mitochondrial NO synthase (NOS) was evaluated. The mitochondrial NOS content and activity (0.2 nmol NO · mg mitochondrial protein−1 · min−1) were ∼10 times lower than previously reported for the rat liver. No evidence for mitochondrial NOS-generated NO was found in mitochondrial suspensions based on the lack of NO production and the lack of effect of eitherl-arginine or NOS inhibitors on the rate of respiration. The reason that even the low mitochondrial NOS activity did not result in net NO production and met

Gli stili APA, Harvard, Vancouver, ISO e altri

24

Borikov, Oleksii, Nataliia Gorbenko, Olha Ivanova, K. V. Taran, T. S. Litvinova, and Tetiana Kiprich. "SEX DIFFERENCES OF ENDOTHELIAL DYSFUNCTION MARKERS — NITRIC OXIDE SYNTHASE AND HEME OXYGENASE IN RATS WITH 2 TYPE DIABETES MELLITUS." Problems of Endocrine Pathology 66, no. 4 (December 3, 2018): 37–43. http://dx.doi.org/10.21856/j-pep.2018.4.04.

Testo completo

Abstract (sommario):

The effect of type 2 diabetes on the markers of endothelial dysfunction — nitric oxide synthase and heme oxygenase has been studied in rats, depending on sex. It was established that the activity of nitric oxide synthase in the blood vessels of female rats is significantly higher in comparison with males under physiological conditions. Type 2 diabetes leads to the different depression of the nitric oxide synthase activity in the blood vessels of females and males, which eliminates sexual differences in the activity of this enzyme. It was found that in contrast to nitric oxide synthase, the act

Gli stili APA, Harvard, Vancouver, ISO e altri

25

Sibmooh, Nathawut, Barbora Piknova, and Alan N. Schechter. "Ascorbic Acid Catalyzes Nitric Oxide Production from Nitrite Ions." Blood 108, no. 11 (November 16, 2006): 1574. http://dx.doi.org/10.1182/blood.v108.11.1574.1574.

Testo completo

Abstract (sommario):

Abstract We have previously shown that nitrite ions can be reduced by hemoglobin to nitric oxide (NO), a ubiquitous signaling molecule and potent vasodilator. Nitrite serves as a stable tissue and vascular source for NO production; the reduction reaction is maximal at about 50% oxygen saturation values and is enhanced at low pH but little is known about other effectors of this reaction. In the current work, we studied the effect of ascorbic acid on nitrite reduction under physiological conditions using chemiluminescence to quantify NO production. In physiological buffer, this reaction has a ra

Gli stili APA, Harvard, Vancouver, ISO e altri

26

Mabrouk, Nesrine, Silvia Ghione, Véronique Laurens, Stéphanie Plenchette, Ali Bettaieb, and Catherine Paul. "Senescence and Cancer: Role of Nitric Oxide (NO) in SASP." Cancers 12, no. 5 (May 2, 2020): 1145. http://dx.doi.org/10.3390/cancers12051145.

Testo completo

Abstract (sommario):

Cellular senescence is a cell state involved in both physiological and pathological processes such as age-related diseases and cancer. While the mechanism of senescence is now well known, its role in tumorigenesis still remains very controversial. The positive and negative effects of senescence on tumorigenesis depend largely on the diversity of the senescent phenotypes and, more precisely, on the senescence-associated secretory phenotype (SASP). In this review, we discuss the modulatory effect of nitric oxide (NO) in SASP and the possible benefits of the use of NO donors or iNOS inducers in c

Gli stili APA, Harvard, Vancouver, ISO e altri

27

Becerril, Sara, Amaia Rodríguez, Victoria Catalán, Beatriz Ramírez, Xabier Unamuno, Piero Portincasa, Javier Gómez-Ambrosi, and Gema Frühbeck. "Functional Relationship between Leptin and Nitric Oxide in Metabolism." Nutrients 11, no. 9 (September 6, 2019): 2129. http://dx.doi.org/10.3390/nu11092129.

Testo completo

Abstract (sommario):

Leptin, the product of the ob gene, was originally described as a satiety factor, playing a crucial role in the control of body weight. Nevertheless, the wide distribution of leptin receptors in peripheral tissues supports that leptin exerts pleiotropic biological effects, consisting of the modulation of numerous processes including thermogenesis, reproduction, angiogenesis, hematopoiesis, osteogenesis, neuroendocrine, and immune functions as well as arterial pressure control. Nitric oxide (NO) is a free radical synthesized from L-arginine by the action of the NO synthase (NOS) enzyme. Three N

Gli stili APA, Harvard, Vancouver, ISO e altri

28

Cabilla, Jimena P., Sonia A. Ronchetti, Silvana I. Nudler, Eliana A. Miler, Fernanda A. Quinteros, and Beatriz H. Duvilanski. "Nitric oxide sensitive-guanylyl cyclase subunit expression changes during estrous cycle in anterior pituitary glands." American Journal of Physiology-Endocrinology and Metabolism 296, no. 4 (April 2009): E731—E737. http://dx.doi.org/10.1152/ajpendo.90795.2008.

Testo completo

Abstract (sommario):

17β-Estradiol (E2) exerts inhibitory actions on the nitric oxide pathway in rat adult pituitary glands. Previously, we reported that in vivo E2 acute treatment had opposite effects on soluble guanylyl cyclase (sGC) subunits, increasing α1- and decreasing β1-subunit protein and mRNA expression and decreasing sGC activity in immature rats. Here we studied the E2 effect on sGC protein and mRNA expression in anterior pituitary gland from adult female rats to address whether the maturation of the hypothalamus-pituitary axis influences its effects and to corroborate whether these effects occur in ph

Gli stili APA, Harvard, Vancouver, ISO e altri

29

Amarnani, Saral, Belinda Sangrat, and Gautam Chaudhuri. "Effects of selected endothelium-dependent vasodilators on fetoplacental vasculature: physiological implications." American Journal of Physiology-Heart and Circulatory Physiology 277, no. 2 (August 1, 1999): H842—H847. http://dx.doi.org/10.1152/ajpheart.1999.277.2.h842.

Testo completo

Abstract (sommario):

The endothelium-dependent vasodilators ACh, histamine, and bradykinin were studied in the isolated, perfused human placental cotyledon. Histamine caused a decrease in perfusion pressure that was attenuated by cimetidine. Bradykinin, at lower concentrations (10−20 to 10−14 M), produced a concentration-dependent decrease in perfusion pressure, whereas at higher concentrations it produced an increase in perfusion pressure. ACh was without any effect. The decrease in perfusion pressure observed with bradykinin was potentiated by captopril and was significantly attenuated in the presence of HOE-140

Gli stili APA, Harvard, Vancouver, ISO e altri

30

Naseem, K. M., and K. R. Bruckdorfer. "Hydrogen peroxide at low concentrations strongly enhances the inhibitory effect of nitric oxide on platelets." Biochemical Journal 310, no. 1 (August 15, 1995): 149–53. http://dx.doi.org/10.1042/bj3100149.

Testo completo

Abstract (sommario):

Simultaneous application of NO and H2O2 to human platelets at physiologically relevant concentrations increased inhibition of platelet aggregation by NO almost 100-fold. If NO and H2O2 were mixed before the addition to platelets, the inhibitory effect remained but still depended on the presence of NO. This suggested an enhanced sensitivity of the platelets to residual NO in the presence of H2O2. The inhibition by the NO/H2O2 mixture was not due to peroxynitrite and was only partly reversed by radical scavengers. The mechanism includes enhanced formation of cyclic GMP in response to NO in the p

Gli stili APA, Harvard, Vancouver, ISO e altri

31

Bradley, Sophie A., and Joern R. Steinert. "Nitric Oxide-Mediated Posttranslational Modifications: Impacts at the Synapse." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/5681036.

Testo completo

Abstract (sommario):

Nitric oxide (NO) is an important gasotransmitter molecule that is involved in numerous physiological processes throughout the nervous system. In addition to its involvement in physiological plasticity processes (long-term potentiation, LTP; long-term depression, LTD) which can include NMDAR-mediated calcium-dependent activation of neuronal nitric oxide synthase (nNOS), new insights into physiological and pathological consequences of nitrergic signalling have recently emerged. In addition to the canonical cGMP-mediated signalling, NO is also implicated in numerous pathways involving posttransl

Gli stili APA, Harvard, Vancouver, ISO e altri

32

Grant, Melissa M., and Daniel Jönsson. "Next Generation Sequencing Discoveries of the Nitrate-Responsive Oral Microbiome and Its Effect on Vascular Responses." Journal of Clinical Medicine 8, no. 8 (July 26, 2019): 1110. http://dx.doi.org/10.3390/jcm8081110.

Testo completo

Abstract (sommario):

Cardiovascular disease is a worldwide human condition which has multiple underlying contributing factors: one of these is long-term increased blood pressure—hypertension. Nitric oxide (NO) is a small nitrogenous radical species that has a number of physiological functions including vasodilation. It can be produced enzymatically through host nitric oxide synthases and by an alternative nitrate–nitrite–NO pathway from ingested inorganic nitrate. It was discovered that this route relies on the ability of the oral microbiota to reduce nitrate to nitrite and NO. Next generation sequencing has been

Gli stili APA, Harvard, Vancouver, ISO e altri

33

Ferreira, Leonardo Cesar, and Ana Catarina Cataneo. "Nitric oxide in plants: a brief discussion on this multifunctional molecule." Scientia Agricola 67, no. 2 (April 2010): 236–43. http://dx.doi.org/10.1590/s0103-90162010000200017.

Testo completo

Abstract (sommario):

Several studies were carried out in order to improve the knowledge about the occurrence and activity of nitric oxide (NO) in plants. Thus, this review discusses some aspects related to NO in plants such as chemical properties, synthesis pathways, physiological effects, antioxidant action, signal transduction, interaction with plant hormones and gene expression. In the last years, many advances have been obtained regarding NO synthesis and its physiological effects in plants. However, the molecular mechanisms underlying its effects remain poorly understood. It is signalized that tight interplay

Gli stili APA, Harvard, Vancouver, ISO e altri

34

Ortiz, Pablo A., and Jeffrey L. Garvin. "Role of nitric oxide in the regulation of nephron transport." American Journal of Physiology-Renal Physiology 282, no. 5 (May 1, 2002): F777—F784. http://dx.doi.org/10.1152/ajprenal.00334.2001.

Testo completo

Abstract (sommario):

Nitric oxide (NO) plays an important role in various physiological processes in the kidney. In vivo experiments first suggested that the natriuretic and diuretic effects caused by NO may be due to decreased NaCl and fluid absorption by the nephron. In the last 10 years, several reports have directly demonstrated a role for NO in modulating transport in different tubule segments. The effects of NO on proximal tubule transport are still controversial. Both stimulation and inhibition of net fluid and bicarbonate have been reported in this segment, whereas only inhibitory effects of NO have been f

Gli stili APA, Harvard, Vancouver, ISO e altri

35

Martusevich, Andrew K., Lida K. Kovaleva, Konstantin A. Karuzin, Alexandra V. Surovegina, and Mikhail Yu Artamonov. "Influence of Physiological Donor of Nitric Oxide on Blood Serum Crystallostasis in Rats." Biomedical and Pharmacology Journal 15, no. 1 (March 31, 2022): 499–504. http://dx.doi.org/10.13005/bpj/2390.

Testo completo

Abstract (sommario):

The aim of the work was to study the effect of intraperitoneal administration of dinitrosyl iron complexes with glutathione ligands on the initiated crystallogenesis of rat blood serum. The experiment was performed on 70 male Wistar rats divided into 7 equal groups. The first group of animals was intact (without any manipulation). Rats included in the other groups were administered intraperitoneal injection of 1 ml. 0.9% sodium chloride solution daily for 10 days. At the same time, animals of the third to sixth groups were additionally added to the injected solution with dinitrosyl iron comple

Gli stili APA, Harvard, Vancouver, ISO e altri

36

Raoofi, Amir, Ayoob Rostamzadeh, Reza Ahmadi, and Mahdi Heydari. "Effects of nitric oxide on reproductive organs and related physiological processes." Asian Pacific Journal of Reproduction 9, no. 4 (2020): 159. http://dx.doi.org/10.4103/2305-0500.288583.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

37

Mehta, Bhupesh, Gulnaz Begum, Nanda B. Joshi, and Preeti G. Joshi. "Nitric Oxide–mediated Modulation of Synaptic Activity by Astrocytic P2Y Receptors." Journal of General Physiology 132, no. 3 (August 25, 2008): 339–49. http://dx.doi.org/10.1085/jgp.200810043.

Testo completo

Abstract (sommario):

We investigated the mechanism of synaptic suppression by P2Y receptors in mixed hippocampal cultures wherein networked neurons exhibit synchronized Ca2+ oscillations (SCO) due to spontaneous glutamatergic synaptic transmission. Pharmacological studies suggested that SCO suppression was mediated by P2Y2/P2Y4 receptors. Immunostaining studies and characterization of ATP/UTP-stimulated Ca2+ responses in solitary neurons and astrocytes revealed that the SCO attenuation was effectuated by astrocytes. We demonstrate that nitric oxide released from activated astrocytes causes synaptic suppression by

Gli stili APA, Harvard, Vancouver, ISO e altri

38

Prado, Carla M., Edna A. Leick-Maldonado, David I. Kasahara, Vera L. Capelozzi, Milton A. Martins, and Iolanda F. L. C. Tibério. "Effects of acute and chronic nitric oxide inhibition in an experimental model of chronic pulmonary allergic inflammation in guinea pigs." American Journal of Physiology-Lung Cellular and Molecular Physiology 289, no. 4 (October 2005): L677—L683. http://dx.doi.org/10.1152/ajplung.00010.2005.

Testo completo

Abstract (sommario):

Endogenously produced nitric oxide is a recognized regulator of physiological lung events, such as a neurotransmitter and a proinflammatory mediator. We tested the differences between chronic and acute nitric oxide inhibition by Nω-nitro-l-arginine methyl ester (l-NAME) treatment in lung mechanics, inflammation, and airway remodeling in an experimental asthma model in guinea pigs. Both acute and chronic l-NAME treatment reduced exhaled nitric oxide in sensitized animals ( P < 0.001). Chronic l-NAME treatment increased baseline and maximal responses after antigen challenge of respiratory sys

Gli stili APA, Harvard, Vancouver, ISO e altri

39

Chang, Jason Y. H., W. Daniel Stamer, Jacques Bertrand, A. Thomas Read, Catherine M. Marando, C. Ross Ethier, and Darryl R. Overby. "Role of nitric oxide in murine conventional outflow physiology." American Journal of Physiology-Cell Physiology 309, no. 4 (August 15, 2015): C205—C214. http://dx.doi.org/10.1152/ajpcell.00347.2014.

Testo completo

Abstract (sommario):

Elevated intraocular pressure (IOP) is the main risk factor for glaucoma. Exogenous nitric oxide (NO) decreases IOP by increasing outflow facility, but whether endogenous NO production contributes to the physiological regulation of outflow facility is unclear. Outflow facility was measured by pressure-controlled perfusion in ex vivo eyes from C57BL/6 wild-type (WT) or transgenic mice expressing human endothelial NO synthase (eNOS) fused to green fluorescent protein (GFP) superimposed on the endogenously expressed murine eNOS (eNOS-GFPtg). In WT mice, exogenous NO delivered by 100 μM S-nitroso-

Gli stili APA, Harvard, Vancouver, ISO e altri

40

Asiimwe, Nicholas, Seung Geun Yeo, Min-Sik Kim, Junyang Jung, and Na Young Jeong. "Nitric Oxide: Exploring the Contextual Link with Alzheimer’s Disease." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/7205747.

Testo completo

Abstract (sommario):

Neuronal inflammation is a systematically organized physiological step often triggered to counteract an invading pathogen or to rid the body of damaged and/or dead cellular debris. At the crux of this inflammatory response is the deployment of nonneuronal cells: microglia, astrocytes, and blood-derived macrophages. Glial cells secrete a host of bioactive molecules, which include proinflammatory factors and nitric oxide (NO). From immunomodulation to neuromodulation, NO is a renowned modulator of vast physiological systems. It essentially mediates these physiological effects by interacting with

Gli stili APA, Harvard, Vancouver, ISO e altri

41

Hadi, Faheem, Tahir Maqbool, Tahir Muhammad, Shabana Akhtar, Muhammad Rafiq, Sana Javed Awan, Tania Ahmad Shakoori, and Asima Tayyeb. "A Review on anticancer potential of Nitric Oxide." International Journal of Natural Medicine and Health Sciences 1, no. 4 (September 30, 2022): 31–35. http://dx.doi.org/10.52461/ijnms.v1i4.1018.

Testo completo

Abstract (sommario):

Nitrous oxide (N2O; laughing gas) is clinically used as a safe anesthetic (dentistry, ambulance, childbirth) and is appreciated for its anti-anxiety effect. Nitrous oxide (N2O) is a free radical gas that performs various physiological and pathological processes in the body. NO is produced by different enzymatic pathways and plays a role in homeostasis. Over the past years, NO has emerged as a molecule of interest in many ailments including cancer. But its role in cancer is still controversy. It can display dose-dependent anticancer therapy on the one hand and induce pro-cancer properties on th

Gli stili APA, Harvard, Vancouver, ISO e altri

42

Korokin, Mikhail, Oleg Gudyrev, Vladimir Gureev, Liliya Korokina, Anna Peresypkina, Tatyana Pokrovskaia, Galina Lazareva, Vladislav Soldatov, Mariya Zatolokina, and Mikhail Pokrovskii. "Studies to Elucidate the Effects of Furostanol Glycosides from Dioscorea deltoidea Cell Culture in a Rat Model of Endothelial Dysfunction." Molecules 25, no. 1 (December 31, 2019): 169. http://dx.doi.org/10.3390/molecules25010169.

Testo completo

Abstract (sommario):

Currently, there is no doubt surrounding a theory that the cardiotropic effects of sex hormones can be due to their direct effect on the cardiovascular system. In recent years, interest in the study of steroid glycosides has increased. We studied the effects of furostanol glycosides (protodioscin and deltozid) from the cell culture of the Dioscorea deltoidea (laboratory code DM-05) on the physiological and biochemical parameters of vascular endothelial function in hypoestrogen-induced endothelial dysfunction after bilateral ovariectomy. It was shown that the use of DM-05 at a dose of 1 mg/kg m

Gli stili APA, Harvard, Vancouver, ISO e altri

43

Thomas, Jeffrey E. "Molecular biological considerations in cerebral vasospasm following aneurysmal subarachnoid hemorrhage." Neurosurgical Focus 3, no. 3 (September 1997): E5. http://dx.doi.org/10.3171/foc.1997.3.3.6.

Testo completo

Abstract (sommario):

Chronic delayed cerebral vasospasm (CDCV) remains a serious and often fatal complication of aneurysmal subarachnoid hemorrhage (SAH). The current understanding of its fundamental mechanisms and molecular biological characterization is rudimentary. Two important vasoactive substances have been implicated in CDCV: endothelin-1 (ET-1) and nitric oxide (NO). A 21-amino acid vasoconstrictor peptide, ET-1 has generated interest as a possible important contributor to cerebral vasospasm on the basis of both clinical and experimental evidence suggesting abnormally enhanced production. Nitric oxide is a

Gli stili APA, Harvard, Vancouver, ISO e altri

44

Arnal, J. F., J. Yamin, S. Dockery, and D. G. Harrison. "Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth." American Journal of Physiology-Cell Physiology 267, no. 5 (November 1, 1994): C1381—C1388. http://dx.doi.org/10.1152/ajpcell.1994.267.5.c1381.

Testo completo

Abstract (sommario):

Cell growth influences the expression of several important tissue-specific functions. We sought to examine the effect of cell proliferation on nitric oxide (NO) synthase gene expression in cultured aortic bovine endothelial cells. Western and Northern blot analysis revealed three- and sixfold increases in NO synthase protein and mRNA, respectively, in growing compared with growth-arrested cells. The release of nitrogen oxides was also increased in proliferating cells compared with growth-arrested cells, as was the NO synthase activity assessed by L-arginine/L-citrulline conversion. Neither NO

Gli stili APA, Harvard, Vancouver, ISO e altri

45

Triastuti, Nenny, Muhammad Perdana Airlangga, and Muhammad Anas. "Usage of Inhaled Nitric Oxides in Cases of Eisenmenger Syndrome." Indonesian Journal of Medical Sciences and Public Health 1, no. 1 (June 30, 2020): 13–19. http://dx.doi.org/10.11594/ijmp.01.01.03.

Testo completo

Abstract (sommario):

Eisenmenger Syndrome is congenital heart disease with pulmonary hypertension and shunting turning from right to left. The resistance of pulmonary vascular more than 7.5 mmHg/L/min. The right ventricle and pulmonary artery always enlarge. Physiological effects of inhaled nitric oxide therapy cause selective pulmonary vasodilation: Hypoxia alveoli causes reversible vasoconstriction, thereby increasing pulmonary wedge pressure. Inhaled nitric oxide can lower it. Moderate cardiac output and systematic arterial pressure are not affected; Selective in pulmonary because it is activated by hemoglobin;

Gli stili APA, Harvard, Vancouver, ISO e altri

46

Balon, Thomas W., and Jerry L. Nadler. "Evidence that nitric oxide increases glucose transport in skeletal muscle." Journal of Applied Physiology 82, no. 1 (January 1, 1997): 359–63. http://dx.doi.org/10.1152/jappl.1997.82.1.359.

Testo completo

Abstract (sommario):

Balon, Thomas W., and Jerry L. Nadler. Evidence that nitric oxide increases glucose transport in skeletal muscle. J. Appl. Physiol. 82(1): 359–363, 1997.—Nitric oxide synthase (NOS) is expressed in skeletal muscle. However, the role of nitric oxide (NO) in glucose transport in this tissue remains unclear. To determine the role of NO in modulating glucose transport, 2-deoxyglucose (2-DG) transport was measured in rat extensor digitorum longus (EDL) muscles that were exposed to either a maximally stimulating concentration of insulin or to an electrical stimulation protocol, in the presence of N

Gli stili APA, Harvard, Vancouver, ISO e altri

47

BALDRIDGE, WILLIAM H., and ANDY J. FISCHER. "Nitric oxide donor stimulated increase of cyclic GMP in the goldfish retina." Visual Neuroscience 18, no. 6 (November 2001): 849–56. http://dx.doi.org/10.1017/s0952523801186013.

Testo completo

Abstract (sommario):

Nitric oxide (NO) activates soluble guanylyl cyclase (sGC) and the resulting increase in cyclic guanosine monophosphate (cGMP) is an important intracellular signalling pathway in the vertebrate retina. Immunocytochemical detection of cGMP following exposure to NO donors has proven an effective method of identifying cells that express sGC. While such an approach has proven useful for the study of several vertebrate retinas, it has not been applied to the well-characterized teleost retina. Therefore, in the present study, we have applied this approach to the retina of the goldfish (Carassius aur

Gli stili APA, Harvard, Vancouver, ISO e altri

48

Zemel, Esther, Orly Eyal, Bo Lei, and Ido Perlman. "NADPH diaphorase activity in mammalian retinas is modulated by the state of visual adaptation." Visual Neuroscience 13, no. 5 (September 1996): 863–71. http://dx.doi.org/10.1017/s0952523800009111.

Testo completo

Abstract (sommario):

AbstractNADPH diaphorase histochemistry is commonly used to identify cells containing nitric oxide synthase (NOS), the enzyme catalyzing the production of nitric oxide from L-arginine. NADPH diaphorase activity and NOS immunostaining was demonstrated in different cells of the vertebrate retina; photoreceptors, horizontal cells, amacrine cells, ganglion cells, and Müller cells. However, the physiological role of nitric oxide (NO) in the retina has yet to be elucidated. In this study, we tested the assumption that NADPH diaphorase activity in the retinas of rabbits and rats depended on the state

Gli stili APA, Harvard, Vancouver, ISO e altri

49

Miller, N., R. Saada, S. Markovich, I. Hurwitz, and A. J. Susswein. "l-arginine via nitric oxide is an inhibitory feedback modulator of Aplysia feeding." Journal of Neurophysiology 105, no. 4 (April 2011): 1642–50. http://dx.doi.org/10.1152/jn.00827.2010.

Testo completo

Abstract (sommario):

An increase in l-arginine hemolymph concentration acts as a postingestion signal inhibiting Aplysia feeding. At physiological concentrations (a 10-μM increase over background), the inhibitory effect of l-arginine is too weak to block feeding in hungry animals. However, a 10-μM increase in l-arginine concentration acts along with another inhibitory stimulus, the sustained presence of food odor, to inhibit feeding after a period of access to food. A physiological concentration of l-arginine also blocked the excitatory effect of a stimulus enhancing feeding, pheromones secreted by mating conspeci

Gli stili APA, Harvard, Vancouver, ISO e altri

50

Henson, Sarah E., Timothy C. Nichols, V. Michael Holers та David R. Karp. "The Ectoenzyme γ-Glutamyl Transpeptidase Regulates Antiproliferative Effects of S-Nitrosoglutathione on Human T and B Lymphocytes". Journal of Immunology 163, № 4 (15 серпня 1999): 1845–52. http://dx.doi.org/10.4049/jimmunol.163.4.1845.

Testo completo

Abstract (sommario):

Abstract Expression of the ectoenzyme γ-glutamyl transpeptidase (GGT) is regulated on T lymphocytes. It is present at a low level on naive T cells, at a high level on activated T cells, and at an intermediate level on resting memory T cells. GGT cleaves the glutamyl group from glutathione, which is the first step in the uptake of extracellular glutathione. In vitro, purified GGT also metabolizes the naturally occurring nitrosothiol, S-nitrosoglutathione (GSNO). Because of this relationship, the effects of cellular GGT on the metabolism of and cellular response to GSNO were tested. The GGT-nega

Gli stili APA, Harvard, Vancouver, ISO e altri

Offriamo sconti su tutti i piani premium per gli autori le cui opere sono incluse in raccolte letterarie tematiche. Contattaci per ottenere un codice promozionale unico!