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1

Acum, Michelle. "End of pathway cleft surgery : exploring the patient-reported outcomes and young people's decision making experiences." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/68908/.

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Objective: Literature exploring how young people (YP) experience cleft surgery at the end of the treatment pathway is limited, both in terms of their reported outcomes and their experience of deciding whether to undergo surgery. This thesis aimed to add to the cleft field by reviewing the patient-reported outcomes (PROs) of end of pathway cleft surgery and exploring YP’s experiences of deciding whether to undergo orthognathic surgery (OS; an end of pathway cleft surgery). Design: A systematic literature search identified studies measuring the PROs of undergoing end of pathway cleft surgery. To
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2

Jayakumar, Prakash. "Patient reported outcome (PRO) measurement of disability in orthopaedic trauma to the upper extremity." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:4f39d510-c902-4112-8806-4eefb9bf25d3.

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Patient reported outcome (PRO) measurement of disability is integral to a patient-centered approach to health care and gauging the biopsychosocial impact of health conditions from the patient's perspective. This thesis investigates disability after proximal humerus, elbow and distal radius fractures; conditions that constitute a major burden in musculoskeletal health care and a substantial impact on health-related quality of life (HrQoL). Disability is defined by the World Health Organisation (WHO) International Classification of Disability, Functioning and Health (ICF) as ‘a multi-dimension
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3

Crocker, Helen. "Coeliac disease : health-related quality of life and patients' experiences of health care services." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:7758bef9-d019-4b9f-b992-d7bf453ad427.

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Coeliac disease (CD) is a chronic gastrointestinal condition, the only treatment for which is a gluten-free diet (GFD). Following a GFD is restrictive, burdensome, and can impact health-related quality of life (HRQOL). People with CD can experience long delays to diagnosis and evidence suggests large variations in follow-up care, but the relationship between health care experiences and HRQOL is unknown. The main aim of this research was to develop a patient-reported outcome measure and patient experience questionnaire, and use these to investigate the relationship between adults' experiences o
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4

Fitzpatrick, Janet M. "Patient-based outcomes : older adults' perceptions of hospital and recovery experiences /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq54846.pdf.

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5

Larsson, Ing-Marie. "Post-Cardiac Arrest Care : Therapeutic Hypothermia, Patient Outcomes and Relatives’ Experiences." Doctoral thesis, Uppsala universitet, Institutionen för kirurgiska vetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-229758.

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The overall aim of the thesis was to study post-resuscitation care of cardiac arrest (CA) patients with a focus on therapeutic hypothermia treatment, outcomes up to six months post-CA and relatives’ experiences during the hospital stay. In Paper I, the aim was to asses effectiveness of hypothermia treatment with cold, 4°C, intravenous crystalloid infusion combined with ice packs. In conclusion, the described cooling method was found to be useful for inducing and maintaining hypothermia, allowed good temperature control during rewarming and to be feasible in clinical practice. The aim in Paper
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6

Wallin, Ewa. "Post Cardiac Arrest Care : Evaluation of prognostic tools, Patient outcomes and Relatives’ experiences at 6 months after the event." Doctoral thesis, Uppsala universitet, Anestesiologi och intensivvård, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-248044.

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The overall aim of the present thesis was to study post-resuscitation care of cardiac arrest (CA) patients treated with target temperature management 33°C with a focus on evaluation of two prognostic tools: variations in cerebral venous saturation and acute magnetic resonance imaging (MRI) findings on the brain post-CA. An additional aim was to investigate patients’ neurological outcome and relatives’ experiences 6 months after the event. Paper I describes the cerebral oxygen saturation of blood obtained from a jugular bulb (SjvO2) catheter The results showed that patients with poor outcome te
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7

Lundin, Karin. "Experiences from Cochlear Implantation and Auditory Brainstem Implantation in Adults and Children : Electrophysiological Measurements, Hearing Outcomes and Patient Satisfaction." Doctoral thesis, Uppsala universitet, Institutionen för kirurgiska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-275091.

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Cochlear implants (CIs) and auditory brainstem implants (ABIs) are prostheses for hearing used in patients with profound hearing impairment. A CI requires an operational cochlear nerve to function in contrast to an ABI. ABIs were initially designed for adult patients with neurofibromatosis type 2 (NF2), suffering from bilateral vestibular schwannomas. Now ABIs are also used for patients, both adults and children, with congenital cochlear malformations, cochlear nerve hypoplasia/aplasia, and cochlear ossification. The aims of this thesis are to evaluate hearing outcome in patients implanted wit
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8

Marx, Laura. "Parents’ Reflections of their Child’s Initial Visit to Metabolic Clinic: A Qualitative Study." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1553513682882592.

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9

Houweling, Taco August Wilhelm. "Description of outcomes, patient experiences and related costs of care in low back pain patients undergoing chiropractic treatment in the UK." Thesis, University of Portsmouth, 2013. https://researchportal.port.ac.uk/portal/en/theses/description-of-outcomes-patient-experiences-and-related-costs-of-care-in-low-back-pain-patients-undergoing-chiropractic-treatment-in-the-uk(fc402d9b-0521-4b42-a57b-43ee7f641238).html.

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Rationale: The prevalence of low back pain and associated costs to society are high. Despite this, the number of studies investigating observational data on the quality and costs of care in routine health care services, such as chiropractic, is relatively small in comparison to the clinical trial evidence available on the effectiveness and cost-effectiveness of manual therapies for low back pain. Objective: To document the quality and cost of care in low back pain patients undergoing routine chiropractic care in the United Kingdom. Design: Prospective single cohort multi-centre study. Particip
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10

Siddiq, Shabnaz. "Experiences of Parents of Children Diagnosed with Inherited Metabolic Diseases (IMD) in Canada: Qualitative Description and Identification of Patient- and Family-Centred Outcomes." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34273.

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Objectives: The objectives of this thesis were to: (i) understand the experiences of parents/caregivers of children with inherited metabolic diseases (IMDs), including perceptions of the health care system; and (ii) identify important patient/family-centred outcomes for measurement in future studies. Methods: A qualitative study used semi-structured interviews to gain in-depth insight into caregivers’ experiences. In an adapted meta-synthesis study, the qualitative findings were integrated with the results of related research to identify priority outcomes. Results: Twenty-one caregivers w
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11

Guo, Na. "Measuring patient-reported outcomes in tuberculosis." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/28757.

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Objectives: The primary objectives of this thesis were to: (1) measure health-related quality of life (HRQL) and health state utility values (HSUVs) among patients with active tuberculosis (TB) disease and latent tuberculosis infection (LTBI); (2) investigate the relationship betwee HRQL and adverse drug reactions (ADR)among active TB patients; (3) quantify patients' preferences for LTBI preventive treatment. Methods: Two groups of patients were administered questionnaires: (1) Short-Form 36 (SF-36), Health Utility Index (HUI) and a Visual Analog Scale (VAS) were administered to 119 LTBI and
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12

Lingard, Elizabeth Anne. "Patient-Reported Outcomes for Total Knee Arthroplasty." Thesis, University of Newcastle Upon Tyne, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506535.

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McColl, Elaine. "Patient reported outcomes : from selection to interpretation." Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417466.

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14

Inkrot, Simone [Verfasser]. "Patient-reported outcomes in heart failure / Simone Inkrot." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2016. http://d-nb.info/1100388184/34.

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Peroutka, Christopher Ryan. "Patient Reported Outcomes in a Physically Active Population." Thesis, North Dakota State University, 2018. https://hdl.handle.net/10365/28741.

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OBJECTIVE: To examine the efficacy of patient-reported outcome measures in the physically active and to determine whether a relationship exists between general health-related quality of life and specific outcome measures. Instruments used were the DPA, the SF-36, the QuickDASH, and the ASES. METHODS: 42 NCAA Division I athletes completed outcome measures three separate times. Repeated-measures ANOVA was performed and bivariate Pearson correlations were calculated. Additionally, test-retest reliability and minimal detectable change were assessed. Significance was set at ? ? 0.05. RESULTS: Signi
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16

Lauck, Sandra Béatrice. "Change in patient-reported outcomes after cardioverter-defibrillator implantation." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/43914.

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Some people, because they have a genetic predisposition or heart disease, are at high risk for cardiac arrhythmias that could cause their hearts to stop. The implantable cardioverter-defibrillator (ICD) is an effective therapy that recognises abnormal heart beats, can administer an electrical shock to stop a potentially lethal heart rhythm, and affords protection from the devastating consequences of sudden cardiac arrest. Patient-reported outcomes (PROs) are assessments provided directly by patients about various aspects of their health and quality of life. We sought to study the change in PRO
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17

Field, Jonathan Roger. "Collecting and predicting patient reported outcomes in chiropractic practice." Thesis, University of Portsmouth, 2016. https://researchportal.port.ac.uk/portal/en/theses/collecting-and-predicting-patient-reported-outcomes-in-chiropractic-practice(29fdc29d-f462-4dd7-a3ac-a65876736cdb).html.

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The eight refereed publications and four abstracts of presentations which form the basis of this PhD each deal with patient health outcomes. The publications are drawn predominantly from practice based research in chiropractic services. In a systematic review of the impact of Patient Reported Outcome Measures (PROMs) on the process and outcomes of care for a single patient, Paper 1 describes this occurring across four domains; patient assessment and initial clinical decision making, tracking progress and evaluating current treatment efficacy, influencing the patient / clinician relationship an
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18

Aroney, Christine Margaret. "Patient Reported Outcomes From Clinical Trials in Medical Retina." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16054.

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Purpose: To determine the patient-centred effectiveness of treatment with the slow release dexamethasone intravitreal implant (DEX implant) and intravitreal bevacizumab using the Impact of Vision Impairment Questionnaire (IVI), a vision-related quality of life (VRQoL) measure, in patients with visual impairment secondary to centre-involving diabetic macular edema (DMO). Methods: Patients with DMO were enrolled in a phase 2, prospective, multicenter, randomized, single-masked clinical trial and received either DEX implant 4 monthly or bevacizumab monthly, both pro re nata. VRQoL was measured
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Roberts, Natasha. "Implementing patient: Reported outcomes in a medical oncology setting." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/208324/1/Natasha_Roberts_Thesis.pdf.

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This program of research implemented routine symptom self-reporting for oncology patients. Before this program of work, standardised reporting of symptoms had been reported in the research setting as promising to improve quality of life and survival. However it was unknown if this could also be done in the very complex setting of routine cancer care. Doctors, nurses, allied health professionals and patients were interviewed and surveyed to make this intervention useful and usable. The study team facilitated successful integration of this intervention into the allocated clinics, which improved
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20

Gutacker, Nils. "Four essays on performance measures based on patient-reported outcomes." Thesis, University of York, 2015. http://etheses.whiterose.ac.uk/11620/.

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Agency relationships, and associated information symmetries, exist in many areas of economic activity including healthcare. Information on healthcare providers’ relative performance can be used to reduce information asymmetries and hold providers to account. This collection of essays focuses on the appropriate derivation and use of performance measures to incentivise healthcare providers in the English National Health Service (NHS). It gives special consideration to the role of patient self-reported health status measures to assess the differential effect of healthcare providers’ care on their
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21

Klooster, Peter Meindert ten. "Interpreting patient reported outcomes in rheumatology Peter Meindert ten Klooster." Enschede : University of Twente [Host], 2008. http://doc.utwente.nl/59001.

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22

Iyasere, Osasuyi Uyigue. "Cognitive impairment and patient reported outcomes in advanced kidney disease." Thesis, Imperial College London, 2017. http://hdl.handle.net/10044/1/56211.

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Shared decision making is now an integral part of renal practice. Quality of life is therefore an important consideration, especially for older patients. This thesis provides insight into the influence of dialysis modality on quality of life in older people with advanced kidney disease. It also explores the relationship between cognitive impairment and dialysis. Firstly, quality of life measures were compared between older patients on assisted peritoneal dialysis and haemodialysis. Patients on assisted peritoneal dialysis were matched to haemodialysis patients by baseline characteristics. Qual
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23

Glenn, L. Lee. "Patient-Reported Medical Outcomes According to Physician Type and Region." Digital Commons @ East Tennessee State University, 1995. https://dc.etsu.edu/etsu-works/7548.

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The purpose of the present study was to determine whether patients with common foot disorders have different medical outcomes depending on whether podiatrists, orthopedic surgeons, or other physicians provided their medical care in rural or urban areas. A validated medical effectiveness score was formulated using indirect standardization of risk-adjusted morbidity, based on patient reports from a national random household interview survey of 3,270 subjects. Patients in rural and urban areas did not differ significantly in medical outcomes across provider types, but there was a trend for patien
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24

El-Wahsh, Sarah Medhat Mounir Megally Adelsayed. "Uncovering Communication Changes In Multiple Sclerosis: Understanding The Patient Experience And A Way Forward." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29694.

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Multiple sclerosis (MS) is one of the most common neurological conditions affecting young and middle-aged individuals worldwide. There is growing recognition that communication can be affected in MS. Communication is an essential feature of everyday life. We communicate for many reasons; to convey information, share stories, and for social closeness. Accordingly, communication changes can negatively impact relationships, employment, and psychological wellbeing. Nevertheless, communication changes in MS have been under-investigated, with greater emphasis often placed on medical and physical sym
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Singh, Jeshika. "Development of a descriptive system for patient experience." Thesis, Brunel University, 2018. http://bura.brunel.ac.uk/handle/2438/16385.

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Efficient allocation of public resources requires identification, measurement and quantification of costs and benefits of alternative programs. Patient reported outcomes (PROs) are routinely incorporated into economic evaluations of health technologies, but patient experience is often overlooked. This thesis aims to develop a descriptive system for patient experience that can be valued and used to inform economic evaluation. The generation and selection of items is key in the development of any PRO measure. The thesis provides a contemporary overview of recommended methods and those actually u
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Parameswaran, Rajeev. "Clinical and patient-reported outcomes after minimally invasive oesophagectomy for cancer." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544337.

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Froud, Robert. "Improving interpretation of patient-reported outcomes in low back pain trials." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511378.

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Reininghaus, Ulrich. "Improving the measurement of patient-reported outcomes in patients with psychosis." Thesis, Queen Mary, University of London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535513.

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Henderson, Alastair. "Low dose-rate brachytherapy for early prostate cancer : patient selection and assessment of patient reported outcomes." Thesis, University of Surrey, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486095.

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Introduction I Low dose-rate brachytherapy is an accepted treatment for early prostate cancer in the UK. This thesis reports studies of clinical outcome from this treatment in a UK centre. Patients and Methods Prospective observational study in three areas of outcome for patients undergoing low' dose-rate (LDR) seed brachytherapy implants: . 1. Quality of life questionnaires were used to prospectively assess toxicity of 3 LDR brachytherapy treatments: monotherapy+l- androgen deprivation+lexternal beam radiotherapy in a longitudinal study. ii. Post-implant catheter use was correlated with preop
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Turk, E. (Eva). "Patient reported outcomes in elderly patients with Diabetes Mellitus Type 2 in Slovenia." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526203263.

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Abstract The aim of this thesis was to measure patient reported outcomes, such as health related quality of life and general diabetes knowledge of elderly diabetes mellitus type 2 (DMT2) patients in Slovenia. Patient reported outcomes demonstrate patient perspectives when evaluating the delivery of care. In Slovenia, a new, multidisciplinary model of chronic care was introduced in 2011, which yet needs to demonstrate the efficiency, care improvement and cost reduction. Thus, another aim of the study was to research if multidisciplinary teams in diabetes care are economically viable. To achieve
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Andijani, Reem Ibrahim. "Lip Repositioning Surgery for Excessive Gingival Display: Clinical, Radiographic, and Patient-Reported Outcomes." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1530635995724862.

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Chang, Sungwon. "An integrated approach to outcome evaluation : incorporating patient reported outcomes in heart failure." Thesis, Curtin University, 2012. http://hdl.handle.net/20.500.11937/2606.

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Globally individuals and health care systems are facing the burden of chronic illness. The impact of the increasing burden of non-communicable diseases is experienced by individuals and health care systems. Across the globe health care systems are struggling to meet the increasing demands for services within the confines of rising costs and needs for accountability. Beyond costs and treatment allocations, there is an increasing mandate to provide care that is patient centred and appropriate to the needs of the individual. The Innovative Care in Chronic Condition (ICCC) framework has been succe
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LO, MONACO Marika. "Relationship between clinical variables and Patient-Reported Outcomes in patients with psoriatic disease." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/499644.

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Background Psoriatic Arthritis (PsA) is a chronic inflammatory form of Arthritis associated with enthesitis, dactylitis, nail dystrophy, uveitis, and osteitis. PsA is strongly associated with comorbidities such as obesity, metabolic syndrome, and cardiovascular disease. As usual PsA patients are assessed either by rheumatologist or dermatologist but a multiprofessional assessment for those subjects is important to improve their disease control and their quality-of-life. The multidimensional assessment is a new model of care for PsA patients in which a multiprofessional team (rheumatolog
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Patel, Neil. "Evaluation of saliva biomarkers in chronic obstructive pulmonary disease : correlation to patient reported outcomes." Thesis, Keele University, 2016. http://eprints.keele.ac.uk/2467/.

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COPD is a debilitating chronic respiratory disease with a systemic footprint. COPD is a highly heterogeneous disease but invariably its management involves a one-size fits all approach. This fails to address individual variations in disease progression, symptom burden and functional decline. There remains a need for sensitive monitoring tools that could provide personalised care based on patients’ particular phenotypes and informative self-management. This thesis has standardised collection protocols and processing for saliva, a complex bodyfluid which is readily accessible and user-friendly f
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Wahlgren, Thomas. "High dose rate brachytherapy boost for localized prostate cancer : clinical and patient-reported outcomes/." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-931-9/.

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Baldwin, Jennifer Naomi. "1000 Norms Project: self-reported outcome measures across the lifespan." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/16451.

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In healthcare, patient-reported outcome measures (PROs) provide valuable information from the individual’s perspective. Normative reference data for PROs are essential to enable comparisons of results with ‘normal’ scores, however data for many PROs are limited. The aim of this thesis was to develop normative reference data for PROs assessing musculoskeletal symptoms, physical function and health-related quality of life, as well as investigate biopsychosocial factors associated with musculoskeletal symptoms and physical function. An observational study collecting PROs and over 50 physical meas
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Manera, Karine. "Standardised Outcomes in Nephrology – Peritoneal Dialysis (SONG-PD): establishing a core outcome set in peritoneal dialysis." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23662.

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Worldwide, approximately 11% of patients on dialysis receive peritoneal dialysis (PD). Whilst PD may offer more autonomy to patients compared with hemodialysis, patient and caregiver burnout, technique failure, and peritonitis remain major challenges to the success of PD. Improvements in care and outcomes are likely to be mediated by randomised trials of innovative therapies, but will be limited if the outcomes measured and reported are not important for patients and clinicians. The aim of the Standardised Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD) study is to establish a set of core
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Olariu, Elena 1984. "Using patient reported outcomes (PROs) to improve recognition of common mental disorders in primary care." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/459066.

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The main objective of this thesis was to generate evidence on the recognition of common mental disorders (mood and anxiety disorders) in non-specialized healthcare settings and to explore solutions for its improvement. We systematically reviewed the worldwide recognition of anxiety disorders by general practitioners over a period of 34 years. The data we used to investigate ways to improve the detection levels of common mental disorders in this setting came from the Inventory of Depression and Anxiety Symptoms (INSAyD) project. This is a prospective study conducted in a convenience sample of
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Liu, Shao-Hsien. "Impact of Intra-Articular Injection Use on Patient-Reported Outcomes Among Patients with Knee Osteoarthritis." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/897.

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Background: Knee osteoarthritis (OA) is the most common type of OA and is a major cause of pain and thus results in disability for daily activities among persons living in the community. OA currently has no cure. In addition to the conflicting recommendations from clinical guidelines, evidence about the extent to which long-term use of intra-articular injections improves patient outcomes is also lacking. Methods: Using data from the Osteoarthritis Initiative (OAI), marginal structural models (MSMs) applying inverse probability treatment weights (IPTW) were used to examine the effectiveness of
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Liu, Shao-Hsien. "Impact of Intra-Articular Injection Use on Patient-Reported Outcomes Among Patients with Knee Osteoarthritis." eScholarship@UMMS, 2003. http://escholarship.umassmed.edu/gsbs_diss/897.

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Background: Knee osteoarthritis (OA) is the most common type of OA and is a major cause of pain and thus results in disability for daily activities among persons living in the community. OA currently has no cure. In addition to the conflicting recommendations from clinical guidelines, evidence about the extent to which long-term use of intra-articular injections improves patient outcomes is also lacking. Methods: Using data from the Osteoarthritis Initiative (OAI), marginal structural models (MSMs) applying inverse probability treatment weights (IPTW) were used to examine the effectiveness of
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Liegl, Gregor [Verfasser]. "Construct validity of item banking approaches for the assessment of patient-reported outcomes / Gregor Liegl." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1176635220/34.

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Vanier, Antoine. "The concept measurement, and integration of response shift phenomenon in Patient-Reported Outcomes data analyses : on certain methodological and statistical considerations." Thesis, Nantes, 2016. http://www.theses.fr/2016NANT1009/document.

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Les données rapportées par les patients sont maintenant fréquemment utilisées en recherche biomédicale. Ces instruments permettent la mesure de concepts subjectifs tels que la qualité de vie, les niveaux d’anxiété, de douleur, de fatigue. L’interprétation d’une différence de score au cours du temps était basée sur l’hypothèse que le sens des concepts et échelles restai stable au cours du temps dans l’esprit des individus. Cette hypothèse semble aujourd’hui dépassée. L’auto-évaluation d’un concept est maintenant comprise comme contingente de la représentation subjective qu’à un sujet du dit con
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Gates, Lucy. "Do clinical foot and ankle assessments improve the prediction of patient reported outcomes in knee arthroplasty?" Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/388299/.

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Knee arthroplasty (KA) has been considered to be a successful and cost-effective intervention for individuals with severe end stage Osteoarthritis (OA). A number of clinically important predictors of outcomes following KA have been established, however there are still other factors to be identified to improve our ability to recognise patients at risk of poor KA outcomes. Although the relationship between foot, ankle and knee kinematics has become widely accepted, it is not known whether foot and ankle status affect KA outcomes. This thesis therefore aims to determine whether clinical foot and
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Straiton, Nicola. "The acceptability of heart valve replacement procedures, and patient-reported outcomes in adults with aortic stenosis." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29843.

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The incidence of aortic stenosis (AS) is high and increasing alongside the aging of populations in developed countries. Yet the impact of severe AS and associated treatments on the lives of people and their carers who provide support, is poorly understood. This thesis aims to investigate patient-reported outcomes of severe AS and valve replacement for adults living with AS and the acceptability of these replacement procedures for individuals and their carers. A multi-method study was conducted, consisting of two systematic reviews one of which synthesised the evidence for functional ca
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Gilbert, Alexandra Jane. "Optimising individual treatment regimes and patient outcomes through the use of patient-reported toxicity assessments in patients treated with pelvic radiotherapy." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/13268/.

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The primary objectives of this thesis are to develop a systematic method for patients to self-report pelvic radiotherapy adverse events (AE) using electronically collected patient reported outcomes (PROs) in clinical practice and to evaluate patient-reported toxicity in association with radiotherapy dosimetric data and clinical factors. Before testing the research objectives in two observational studies, important practical and methodological issues were addressed. Analysis from systematic and literature reviews, content analysis of three validated PRO systems and interviews with health profes
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Razvi, Salman Syed. "L-thyroxine therapy in subclinical hypothyroidism : effect on cardiovascular risk factors, endothelial function and patient-reported outcomes." Thesis, University of Newcastle Upon Tyne, 2007. http://hdl.handle.net/10443/701.

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Context: It is controversial whether the treatment of subclinical hypothyroidism (SCH) with L-thyroxine improves cardiovascular (CV) risk factors and quality of life (QoL). Objective: To determine whether CV risk factors, endothelial function and patient-reported outcomes improve in people with SCH with L-thyroxine treatment. Design: Randomised double blind, cross-over study. Setting: Patients from primary care practices identified from laboratory database. Patients: One hundred patients (81 females) with mild SCH, and no existing thyroid or vascular disease, mean (SD) age 53.8 (12) years, thy
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Archer, Stephanie. "Treatment beyond treatment : exploring the effects of two complementary interventions on patient reported outcomes of gynaecological cancer." Thesis, University of Derby, 2013. http://hdl.handle.net/10545/305905.

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Gynaecological cancers (which include cancers of the ovary, cervix, uterus, vagina, endometrium, vulva and fallopian tube) account for 19% of all female cancers, and there are approximately 942,000 new cases diagnosed per year worldwide. Treatment for gynaecological cancer is often multi modal and consists of surgery, radiotherapy and chemotherapy. Current government policy has highlighted the need to focus on improving patient reported outcomes, including the patient experience of all aspects of cancer (including treatment), and the quality of life (QoL) of patients living with and beyond a c
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HIGHFILL, TINA C. "PATIENT OUTCOMES AND MANAGED CARE: WHAT WAS THE IMPACT OF THE STATE REGULATORY BACKLASH?" VCU Scholars Compass, 2017. https://scholarscompass.vcu.edu/etd/4854.

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Hundreds of state regulations were passed during the “managed care backlash” of the late 1990s and early 2000s. Many of these anti-managed care regulations eased or eliminated constraints on patient utilization of health care services imposed by managed care organizations. Other regulations gave managed care providers more flexibility in the way they practiced care or helped patients appeal denials of claims. Despite the effort undertaken to pass these regulations, limited research exists on whether the regulations achieved their goal. To fill this gap, this study takes advantage of the variet
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Kaur, Harsimran. "Digitally Enabled, Wearable Remote Patient Monitoring of Clinical Trials to Assess Patient Reported Outcomes-A Systematic Review : Shifting Paradigm from Site-Centric to Patient Centric Health Care." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-45283.

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Summary: Although the digital revolution has transformed many niches of human activity, healthcare sector and pharmaceutical drug development has been relatively slow in embracing emerging technologies to optimize health efficacy, especially in Nordic Countries. The topic is of more importance now owing to the present scenario of the corona virus (COVID-19)outbreak, which has caused unparalleled disruption in the conduct of clinical trials and presented challenges as well as opportunities for clinical trialists and data analysts. In this master thesis, the potential opportunity with virtual or
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ZINI, ELISA MARIA. "Exploitation of Patient-Reported Outcomes in the management of cancer outpatients: integration of mobile technology and digital guidelines." Doctoral thesis, Università degli studi di Pavia, 2019. http://hdl.handle.net/11571/1242426.

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