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Letteratura scientifica selezionata sul tema "Qsp"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 1 febbraio 2022

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Articoli di riviste sul tema "Qsp"

McCausland, Beth, Nicola Minicozzi, Siobhan O'Halloran, Avril Ward e Kerry Elliott. "Increasing staff confidence about domestic abuse identification, disclosure and safeguarding in a community mental health team". BJPsych Open 7, S1 (giugno 2021): S146—S147. http://dx.doi.org/10.1192/bjo.2021.413.

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AimsTo increase staff confidence about identifying Domestic Abuse (DA), particularly regarding ‘how to ask’ to encourage disclosure and the pathways available for appropriately safeguarding survivors; in a Community Mental Health Team (CMHT) setting.BackgroundDA is bi-directionally associated with mental health (MH) disorders; 1:4 women in contact with MH services are currently experiencing DA. MH professionals (MHPs) are in a privileged position to identify DA and support survivors. However, this is dependent on MHPs receiving adequate training about DA. For this, we collaborated with Pathfinder, a national pilot project run by a consortium of five expert partners that aims to establish comprehensive health practice in relation to DA and Violence Against Women & Girls in Acute Hospital Trusts, MH Trusts and Primary Care. In Southampton, Pathfinder has funded two domestic and sexual abuse (DSA) advocates to both train MH staff and take a small caseload of MH service users who are experiencing abuse.MethodWe conducted a baseline survey of staff confidence across the following domains:Knowing the legal definition of DA,The process used to escalate a DA concern,How to make a referral,How to complete DASH forms,How and when to refer to Pathfinder,What the following acronyms mean: PIPPA, MAPPA, MARAC, IDVA, DASH,What HRDA and MASH mean,How to ask about DA,Who to signpost service users to if they make a disclosure, and when to involve the police.We presented the survey results at the regional Pathfinder strategic group, with Trust management representatives present. This project fits within the strategic group's sustainability aims to increase DA awareness and safeguarding processes across the Trust.The Pathfinder funded DSA Advisors delivered a four-hour training package targeting the surveyed questions and wider information on DA. We then re-surveyed to see if staff confidence had increased. We are currently analyzing the number of referrals to the Pathfinder service pre- and post-training.ResultStaff confidence increased across all domains following the training (% mean increase): Qs1 (35%), Qs2 (9%), Qs3 (45%), Qs4 (81%), Qs5 (25%), Qs6 (49%), Qs7 (89%), Qs8 (62%) and Qs9 (48%).We have now arranged a bi-monthly drop-in at the CMHT by the DSA advisor who provided the training, to embed the link between the services and maintain staff confidence. We will circulate these results to advocate that this training is provided across the Trust.

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Song, Yong-jia, Jia-min Bao, Long-yun Zhou, Gan Li, Kim Sia Sng, Yong-jun Wang, Qi Shi e Xue-jun Cui. "An Analysis of the Anti-Neuropathic Effects of Qi She Pill Based on Network Pharmacology". Evidence-Based Complementary and Alternative Medicine 2020 (5 maggio 2020): 1–15. http://dx.doi.org/10.1155/2020/7193832.

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Background. Qi She Pill (QSP) is a traditional prescription for the treatment of neuropathic pain (NP) that is widely used in China. However, no network pharmacology studies of QSP in the treatment of NP have been conducted to date. Objective. To verify the potential pharmacological effects of QSP on NP, its components were analyzed via target docking and network analysis, and network pharmacology methods were used to study the interactions of its components. Materials and Methods. Information on pharmaceutically active compounds in QSP and gene information related to NP were obtained from public databases, and a compound-target network and protein-protein interaction network were constructed to study the mechanism of action of QSP in the treatment of NP. The mechanism of action of QSP in the treatment of NP was analyzed via Gene Ontology (GO) biological process annotation and Kyoto Gene and Genomics Encyclopedia (KEGG) pathway enrichment, and the drug-like component-target-pathway network was constructed. Results. The compound-target network contained 60 compounds and 444 corresponding targets. The key active compounds included quercetin and beta-sitosterol. Key targets included PTGS2 and PTGS1. The protein-protein interaction network of the active ingredients of QSP in the treatment of NP featured 48 proteins, including DRD2, CHRM, β2-adrenergic receptor, HTR2A, and calcitonin gene-related peptide. In total, 53 GO entries, including 35 biological process items, 7 molecular function items, and 11 cell related items, were identified. In addition, eight relevant (KEGG) pathways were identified, including calcium, neuroactive ligand-receptor interaction, and cAMP signaling pathways. Conclusion. Network pharmacology can help clarify the role and mechanism of QSP in the treatment of NP and provide a foundation for further research.

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Kling, Gerhard, Charles Harvey e Mairi Maclean. "Establishing Causal Order in Longitudinal Studies Combining Binary and Continuous Dependent Variables". Organizational Research Methods 20, n. 4 (30 novembre 2015): 770–99. http://dx.doi.org/10.1177/1094428115618760.

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Longitudinal studies with a mix of binary outcomes and continuous variables are common in organizational research. Selecting the dependent variable is often difficult due to conflicting theories and contradictory empirical studies. In addition, organizational researchers are confronted with methodological challenges posed by latent variables relating to observed binary outcomes and within-subject correlation. We draw on Dueker’s qualitative vector autoregression (QVAR) and Lunn, Osorio, and Whittaker’s multivariate probit model to develop a solution to these problems in the form of a qualitative short panel vector autoregression (QSP-VAR). The QSP-VAR combines binary and continuous variables into a single vector of dependent variables, making every variable endogenous a priori. The QSP-VAR identifies causal order, reveals within-subject correlation, and accounts for latent variables. Using a Bayesian approach, the QSP-VAR provides reliable inference for short time dimension longitudinal research. This is demonstrated through analysis of the durability of elite corporate agents, social networks, and firm performance in France. We provide our OpenBUGS code to enable implementation of the QSP-VAR by other researchers.

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van der Graaf, Piet. "SC3.1 - Introduction to QSP". Drug Metabolism and Pharmacokinetics 35, n. 1 (2020): S3. http://dx.doi.org/10.1016/j.dmpk.2020.04.277.

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Matteelli, Alberto, Nuccia Saleri, Zeno Bisoffi, Giampietro Gregis, Giovanni Gaiera, Raffaella Visonà, Simona Tedoldi, Carla Scolari, Stefania Marocco e Maurizio Gulletta. "Mefloquine versus Quinine plus Sulphalene-Pyrimethamine (Metakelfin) for Treatment of Uncomplicated Imported Falciparum Malaria Acquired in Africa". Antimicrobial Agents and Chemotherapy 49, n. 2 (febbraio 2005): 663–67. http://dx.doi.org/10.1128/aac.49.2.663-667.2005.

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ABSTRACT We conducted a multicenter, randomized, open-label trial to compare mefloquine with a 3-day quinine plus sulphalene-pyrimethamine (SP) regimen for the treatment of imported uncomplicated malaria acquired in Africa. The end points of the study were efficacy, tolerability, and length of hospital stay. From July 1999 to February 2003, 187 patients were enrolled in five centers in Italy, of whom 93 were randomized to receive mefloquine (the M group) and 94 were randomized to receive quinine plus SP (the QSP group). Immigrants and visiting relatives and friends represented 90% of the cases and were mainly from western African countries. A slightly increased proportion of cases in the QSP group had abnormal alanine aminotransferase levels at the baseline. The early cure rate was similar in the two groups: 98.9% (confidence interval [CI] = 97 to 100%) in the M group and 96.8% (CI = 93 to 100%) in the QSP group. The extended follow-up was completed by 135 subjects (72.2%), and no case of recrudescence was detected. There were no differences in the parasite clearance time, but patients in the M group had shorter mean fever clearance time (35.9 h versus 44.4 h for the QSP group; P = 0.05) and a shorter mean hospital stay (3.9 days versus 4.6 days for the QSP group; P = 0.007). The overall proportions of reported side effects were similar in the two groups, but patients in the M group had a significantly higher rate of central nervous system disturbances (29.0% versus 9.6% for the QSP group; P < 0.001).

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Meng, Fuxue, e Xiaomai Tao. "Application value of quantitative system pharmacology in drug discovery for traditional Chinese medicine". Journal of Medical Care Research and Review 3, n. 9 (1 settembre 2020): 425–36. http://dx.doi.org/10.15520/mcrr.v3i9.113.

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Quantitative system pharmacology (QSP) is a discipline that combines computational models of systems biology and systems pharmacology. With the development of high-throughput genomics techniques (genomics, transcriptomics, proteomics, and metabolomics) as well as computer and bioinformatics methods, systems biology and systems pharmacology modeling are widely used to comprehend human biology and disease progression, predict the effectiveness and safety of drug candidates. Due to the advancement of big data and high-quality database, the application of QSP, especially the pre-clinical stage that guides early drug discovery, is increasingly widespread. The traditional drug discovery process takes a long time yet has a low success rate. The early intervention and full participation of QSP in the development of new drugs discovery can form a model-led drug development model to improve the efficiency of drug discovery and scientific appraise, reduce the cost of research and development, and shorten the time to market for new drugs. This article reviews the differences between QSP and other quantitative pharmacology, the problems faced by traditional Chinese medicine research, and the value of QSP in traditional Chinese medicine research, with a view to providing reference and support for the research and development of new traditional Chinese medicine.

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Katritzky, Alan R., Svetoslav Slavov, Maksim Radzvilovits, Iva Stoyanova-Slavova e Mati Karelson. "Computational Chemistry Approaches for Understanding how Structure Determines Properties". Zeitschrift für Naturforschung B 64, n. 6 (1 giugno 2009): 773–77. http://dx.doi.org/10.1515/znb-2009-0625.

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The establishment of quantitative relationships between numerous molecular properties and chemical structures is now of great importance to society in understanding and improving environmental, medicinal and technological aspects of life. Quantitative structure-activity (property) relationships (QSA(P)R) relate physical, chemical, physico-chemical, technological and biological properties of compounds to their structure. A major factor driving the widespread use of QSP(A)R models is the rational estimation of properties of new compounds, without first synthesizing and testing them. Some of our recent findings in the field are briefly discussed below.

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Stern, Andrew M., Mark E. Schurdak, Ivet Bahar, Jeremy M. Berg e D. Lansing Taylor. "A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine". Journal of Biomolecular Screening 21, n. 6 (8 marzo 2016): 521–34. http://dx.doi.org/10.1177/1087057116635818.

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Drug candidates exhibiting well-defined pharmacokinetic and pharmacodynamic profiles that are otherwise safe often fail to demonstrate proof-of-concept in phase II and III trials. Innovation in drug discovery and development has been identified as a critical need for improving the efficiency of drug discovery, especially through collaborations between academia, government agencies, and industry. To address the innovation challenge, we describe a comprehensive, unbiased, integrated, and iterative quantitative systems pharmacology (QSP)–driven drug discovery and development strategy and platform that we have implemented at the University of Pittsburgh Drug Discovery Institute. Intrinsic to QSP is its integrated use of multiscale experimental and computational methods to identify mechanisms of disease progression and to test predicted therapeutic strategies likely to achieve clinical validation for appropriate subpopulations of patients. The QSP platform can address biological heterogeneity and anticipate the evolution of resistance mechanisms, which are major challenges for drug development. The implementation of this platform is dedicated to gaining an understanding of mechanism(s) of disease progression to enable the identification of novel therapeutic strategies as well as repurposing drugs. The QSP platform will help promote the paradigm shift from reactive population-based medicine to proactive personalized medicine by focusing on the patient as the starting and the end point.

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Gong, Chang, Alvaro Ruiz-Martinez, Holly Kimko e Aleksander S. Popel. "A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor–Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy". Cancers 13, n. 15 (26 luglio 2021): 3751. http://dx.doi.org/10.3390/cancers13153751.

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Quantitative systems pharmacology (QSP) models have become increasingly common in fundamental mechanistic studies and drug discovery in both academic and industrial environments. With imaging techniques widely adopted and other spatial quantification of tumor such as spatial transcriptomics gaining traction, it is crucial that these data reflecting tumor spatial heterogeneity be utilized to inform the QSP models to enhance their predictive power. We developed a hybrid computational model platform, spQSP-IO, to extend QSP models of immuno-oncology with spatially resolved agent-based models (ABM), combining their powers to track whole patient-scale dynamics and recapitulate the emergent spatial heterogeneity in the tumor. Using a model of non-small-cell lung cancer developed based on this platform, we studied the role of the tumor microenvironment and cancer–immune cell interactions in tumor development and applied anti-PD-1 treatment to virtual patients and studied how the spatial distribution of cells changes during tumor growth in response to the immune checkpoint inhibition treatment. Using parameter sensitivity analysis and biomarker analysis, we are able to identify mechanisms and pretreatment measurements correlated with treatment efficacy. By incorporating spatial data that highlight both heterogeneity in tumors and variability among individual patients, spQSP-IO models can extend the QSP framework and further advance virtual clinical trials.

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Sobha, Varsha V., NK Sapna Varma e VV Ajith. "Comparative Evaluation of Laser Etching and Acid Etching: An in vitro Study". International Journal of Laser Dentistry 6, n. 1 (2016): 6–11. http://dx.doi.org/10.5005/jp-journals-10022-1079.

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ABSTRACT Introduction Recent innovations in bonding propose laser ablation as an alternative method to acid etching. Objectives The objective of this study is to compare the effect of laser irradiation at medium-short pulse (MSP) mode, quantum-square pulse (QSP) mode, and acid etching on the shear bond strength (SBS) of orthodontic brackets to enamel. Materials and methods Forty-two premolars were allocated to three groups (14 each): (1) 37% phosphoric acid etching; (2) erbium-doped yttrium aluminum garnet (Er:YAG) laser etching with MSP mode; (3) Er:YAG laser etching with quantum-square pulse mode. Metallic brackets were bonded with Transbond XT. After photo polymerization, the SBS values were recorded with universal testing machine. Surface morphology was evaluated with scanning electron microscopy (SEM). The remaining adhesive was assessed using adhesive remnant index (ARI). Results Nonparametric test was used to analyze the statistical significance. A mean rank of 18.29 and 10.71 was obtained for QSP mode and acid etching with p = 0.015, 18.14; and 10.86 for MSP mode and acid etching with p = 0.019; and 14 and 15 for QSP mode and MSP mode with p = 0.748. Statistically significant difference was found between laser and acid-etched group. The SEM scan showed MSP mode with regular and uniform surface, like acid-etched sample, whereas QSP samples had irregular and severely rough surface. The ARI indicates that failure sites are mainly at the enamel/adhesive interface in the acid-etched and MSP mode group and at the bracket base/adhesive interface in QSP mode group. Conclusion Laser etching in MSP mode is a successful alternative to acid etching, and provides a safer debonding of the brackets from the enamel surface without causing fractures. How to cite this article Sobha VV, Varma NKS, Ajith VV. Comparative Evaluation of Laser Etching and Acid Etching: An in vitro Study. Int J Laser Dent 2016;6(1):6-11.

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Tesi sul tema "Qsp"

SANTOS, MARCO ANTONIO CETALE. "PHASE-SHIFT DEPTH MIGRATION FOR QP AND QSV WAVEFIELDS ON LOCALLY TRANSVERSE ISOTROPIC (LTI) MEDIA". PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2003. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=4373@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
Este trabalho propõe uma técnica do tipo rotação de fase para migração em profundidade de dados sísmicos para meios com simetria polar local (localmente transversalmente isotrópicos, LTI), nos quais a direção do eixo de simetria varia continuamente ao longo das camadas. São testadas, através de simulações numéricas de levantamentos sísmicos, a precisão e a estabilidade do método, em função da variação do eixo de simetria. Para a realização das simulações, desenvolveu-se um método a partir da solução da equação elástica da onda usando-se a técnica das diferenças finitas, que possibilita a modelagem em meios LTI, onde cada ponto da malha tem suas características definidas pelas velocidades de fase P e SV, parâmetros de Thomsen, densidade e inclinação do eixo de simetria. Na separação dos modos de onda qP e qSV dos sismogramas, implementou-se um algoritmo baseado na solução da equação de Christoffel para determinar os operadores de separação. A migração para cada família de tiro comum é realizada por soluções da equação da onda usando somente técnicas de rotações de fase. De fato, tanto a depropagação do campo registrado quanto a geração das matrizes de tempo utilizadas na condição de imageamento, são realizadas por soluções que envolvem rotações de fase para cada conjunto de parâmetros, em cada nível de profundidade. Nos resultados das migrações usando reflexões dos tipos qP-qP, e qP-qSV, os horizontes foram localizados precisamente e verificou-se que o processo é estável em relação à variação do eixo de simetria. Vale ressaltar que o método não está restrito a aquisições sísmicas multicomponentes, podendo ser aplicado em dados sísmicos marítimos convencionais, como também em dados provenientes de aquisições do tipo OBC (Ocean Bottom Cable) e com cabo vertical. Como o método proposto se baseia em algoritmos que utilizam técnicas de rotação de fase, a sua implementação conta com o beneficio de ser altamente paralelizável.
This work proposes a technique based on the phase-shift method to implement pre-stack depth migration on locally transverse isotropic media (LTI), in which the direction of the symmetry axis varies continually along the layers. Through numerical seismic data simulations the methods robustness and stability were tested in relation to the axis symmetry variations. For seismic modeling, a generalization of the finite differences method for the solution of the elastic wave equation was used. With this procedure, it was possible to accommodate seismic modeling on LTI media defined by six parameters at each grid point, i.e., density, P and S wave propagation velocities along the local symmetry axis, Thomsen parameters and, the direction of the local symmetry axis itself. In order to separate from the seismograms the qP and qSV wavefields, an algorithm based on the Christoffel equation was implemented. The migration for each common shot gather is implemented solely by phase-shift based algorithms, which means that not only the depropagation of the registered wavefield, but also the generation of the time matrices involved in the imaging condition were obtained in this manner for each set of parameters at each depth level. The migration results using qP-qP and qP-qSV reflections show that the horizons were located precisely, and that the process is stable in relation to the symmetry axis variations. The proposed method is not restricted to multicomponent seismic acquisitions, but it can be applied to marine seismic data using streamers, or Ocean Bottom Cables or vertical cables. Since the proposed method uses phaseshift algorithms, its parallel implementation can be highly efficient.

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Outram, Philip James. "QSO absorption systems". Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624575.

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Webb, J. K. "QSO absorption lines". Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234000.

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The absorption lines found in the spectra of distant quasars provide a unique method of probing the physical conditions in the universe at early epochs. This thesis describes a study of the Lyman alpha forest absorption systems seen in the spectra of high redshift QSOs. The Anglo-Australian Telescope has been used to obtain high resolution spectra of several bright QSOs. Considerable effort has gone into developing statistical techniques for profile fitting to the data to objectively and reliably extract the parameters associated with each absorbing cloud. The distribution functions for these are given and discussed. Particular attention has been paid to the clustering properties of the Lyman alpha clouds and it is found that they are weakly (but significantly) clustered on small velocity scales. Possible interpretations of this result are discussed. One especially interesting aspect of QSO absorption systems concerns the potential for measuring, or obtaining limits on, the deuterium to hydrogen abundance at high redshifts. A knowledge of this quantity is important for constraining cosmological models and can also help us to understand the chemical evolution of light elements in galaxies. A series of numerical simulations has been carried out to explore the potential for such measurements and an absorption system has been analysed to obtain an upper limit to D/H at z = 3.

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Smith, Robert James. "QSO clustering and environments". Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624809.

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Jahnke, Knud. "Stellar populations of QSO host galaxies". [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965227995.

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Zare, Haidi. "On spherical classes in H*QSⁿ". Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499135.

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We consider the problem of determining spherical classes In H*QS¹. We take a geometrical approach and show how existence of specific classes as a spherical class In H*QS¹ will determine the type of homology operations that can detect the related homotopy class. Most of our results here are quite general, and can be applied to H*QX, with X an arbitrary path connected space. We see this as an approach to attack the conjecture of Ed Curtis about spherical classes in H*Q₀S⁰.

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Ellison, S. L. "The chemical evolution of QSO absorbers". Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598835.

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Using quasar absorption lines as a probe of the high redshift universe is a powerful tool in the field of chemical evolution. In this thesis, I consider the elemental abundances in absorbers that correspond to a variety of environments, ranging from high redshift galaxies to the low density intergalactic medium. I firstly address the question of abundances in intermediate redshift (z_abs < 1.5) damped Lyα systems (DLAs), objects believed to correspond to the progenitors of present day massive galaxies. I present Hubble Space Telescope (HST) spectra of six intermediate redshift DLAs which have been supplemented with high resolution spectroscopy obtained with the high resolution echelle spectrograph (HIRES) on the Keck telescope. The chemical abundances of a range of elements are investigated and compared with local Galactic values in order to gain an insight into the metallicities, dust-to-gas ratios and star formation histories of these systems. The results from this work have inspired a new survey for DLAs based on a radio-selected sample of QSOs. The motivation for this endeavour has been to determine the extent to which our current view of distant galaxies is obscured by dust. I present intermediate resolution spectra obtained at the Anglo-Australian Telescope (AAT) from which DLAs may be identified. The number statistics of the newly discovered DLAs are analysed in order to determine whether obscuration by dust of background QSOs causes a significant observational bias. Finally, I consider the metallicity of the IGM by studying C IV systems associated with the Lyα forest at z ~ 3. The extent to which the IGM has been polluted with metals will provide important clues to the enrichment mechanism. I firstly investigate the column density distribution function of strong C IV absorbers associated with high column density Lyα clouds. This work is then extended to consider the C IV/H 1 ratio in low column density absorbers which are associated with physically less dense material. The spectra of two high redshift QSOs are analysed using two different techniques, both of which are critically assessed using synthetic spectra.

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Larrea, Erik Aris Stengler. "Cosmological evolution of QSO absorption systems". Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339588.

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Natale, Louis, e John Roach. "The F-22A Quick Response Package-QRP". International Foundation for Telemetering, 2011. http://hdl.handle.net/10150/595676.

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ITC/USA 2011 Conference Proceedings / The Forty-Seventh Annual International Telemetering Conference and Technical Exhibition / October 24-27, 2011 / Bally's Las Vegas, Las Vegas, Nevada
The F-22 Quick Response Package was designed to efficiently solve aircraft anomalies in the field. Providing this capability would enhance aircraft combat availability and lower maintenance costs. Using the current F-22 instrumentation flight test system design package as a baseline, a smaller, and much more versatile, version of the system was designed. This new design concept includes a data acquisition and recording system on a single pallet called the Quick Response Package (QRP). The QRP can be installed in any operational F-22 war fighter in a single production shift with no intrusion to the aircraft's systems readiness. The data acquisition and recording capabilities provide a near real-time field solution without excessive downtime or pilot intervention. This paper describes the design requirements, the design concept and packaging details of the QRP.

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López-Corredoira, M., F. Melia, E. Lusso e G. Risaliti. "Cosmological test with the QSO Hubble diagram". World Scientific Publishing, 2016. http://hdl.handle.net/10150/615119.

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A Hubble diagram (HD) has recently been constructed in the redshift range $0\lesssim z\lesssim 6.5$ using a non-linear relation between the ultraviolet and X-ray luminosities of QSOs. The Type Ia SN HD has already provided a high-precision test of cosmological models, but the fact that the QSO distribution extends well beyond the supernova range ($z\lesssim 1.8$), in principle provides us with an important complementary diagnostic whose significantly greater leverage in $z$ can impose tighter constraints on the distance versus redshift relationship. In this paper, we therefore perform an independent test of nine different cosmological models, among which six are expanding, while three are static. Many of these are disfavoured by other kinds of observations (including the aforementioned Type Ia SNe). We wish to examine whether the QSO HD confirms or rejects these earlier conclusions. We find that four of these models (Einstein-de Sitter, the Milne universe, the Static Universe with simple tired light and the Static universe with plasma tired light) are excluded at the $>99\%$ C.L. The Quasi-Steady State Model is excluded at $>95$\% C.L. The remaining four models ($\Lambda$CDM/$w$CDM, the $R_{\rm h}=ct$ Universe, the Friedmann open universe and a Static universe with a linear Hubble law) all pass the test. However, only $\Lambda$CDM/$w$CDM and $R_{\rm h}=ct$ also pass the Alcock-Paczy\'nski (AP) test. The optimized parameters in $\Lambda$CDM/$w$CDM are $\Omega _m=0.20^_$ and $w_{de}=-1.2^_$ (the dark-energy equation-of-state). Combined with the AP test, these values become $\Omega _m=0.38^_$ and $w_{de}=-0.28^_$. But whereas this optimization of parameters in $\Lambda$CDM/$w$CDM creates some tension with their concordance values, the $R_=ct$ Universe has the advantage of fitting the QSO and AP data without any free parameters.

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Più fonti

Libri sul tema "Qsp"

Kleinman, Joel, e Zack Lau. QRP power: The best recent QRP articles from QST, QEX, and the ARRL handbook. Newington, CT: American Radio Relay League, 1996.

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Dobbs, George. QRP basics. Potters Bar, Herts: Radio Society of Great Britain, 2003.

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DeMaw, Doug. W1FB's QRP notebook. 2^a ed. Newington, CT: American Radio Relay League, 1991.

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Meylan, Georges, a cura di. QSO Absorption Lines. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-540-49458-4.

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Martell, Dan. QaP: Queer AIDS poems. Port Carling, Ont., Canada: D. Martell, 1995.

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Programme, Quality Assurance. QAP topical reading lists. London: King's Fund Centre, Quality Assurance Programme, 1990.

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Projects, Quaker International Social. QISP opportunities abroad 1992. London: QISP, 1992.

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Martell, Dan. QaP: Queer AIDS poems. Port Carling, Ont., Canada: D. Martell, 1995.

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Tennant, Allyn F. The QDP/PLT user's guide. Marshall Space Flight Center, Ala: George C. Marshall Space Flight Center, 1991.

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Márquez, Isabel, Josefa Masegosa, Ascensión del Olmo, Lucas Lara, Emilio García e Josefina Molina, a cura di. QSO Hosts and Their Environments. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-0695-9.

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Capitoli di libri sul tema "Qsp"

Smith, James, e Kai Xu. "Serial & parallel algorithms for QSP problems". In Parallel Processing of Discrete Optimization Problems, 353–74. Providence, Rhode Island: American Mathematical Society, 1995. http://dx.doi.org/10.1090/dimacs/022/16.

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Weik, Martin H. "QST". In Computer Science and Communications Dictionary, 1381. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_15181.

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Petroianu, Georg, e Peter Michael Osswald. "Querschnittsyndrom (QSS)". In Anästhesie in Frage und Antwort, 151–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-05716-2_60.

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Schlobohm, Bernd. "QSC AG". In Deutsche Standards, 284–87. Wiesbaden: Gabler Verlag, 2005. http://dx.doi.org/10.1007/978-3-322-93425-3_69.

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Schlobohm, Bernd. "QSC AG". In Deutsche Standards Beispielhafte Geschäftsberichte, 268–71. Wiesbaden: Gabler Verlag, 2004. http://dx.doi.org/10.1007/978-3-322-99378-6_65.

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Sippl, Wolfgang, e Dina Robaa. "QSAR/QSPR". In Applied Chemoinformatics, 9–52. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527806539.ch2.

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Petroianu, Georg, e Peter Michael Osswald. "Querschnittsyndrom (QSS)". In Anästhesie in Frage und Antwort, 233–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-05717-9_99.

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Petroianu, Georg, e Peter Michael Osswald. "Querschnittsyndrom (QSS)". In Anästhesie in Frage und Antwort, 393–94. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-05715-5_139.

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Cordell, Andrea, e Ian Thompson. "Q:P Tender Evaluation". In The Procurement Models Handbook, 33–35. Third edition. | Abingdon, Oxon ; New York, NY : Routledge, 2019. | Earlier editions published as: Purchasing models handbook: a guide to the most popular business models used in purchasing / Andrea Reynolds and Ian Thompson.: Routledge, 2019. http://dx.doi.org/10.4324/9781351239509-11.

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Roy, Kunal, Supratik Kar e Rudra Narayan Das. "QSAR/QSPR Methods". In SpringerBriefs in Molecular Science, 61–103. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17281-1_3.

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Atti di convegni sul tema "Qsp"

Abraham, J. Dani, R. M. Sasiraja e D. Prince Winston. "Quality Span Prediction (QSP) of Solar Photovoltaic Panels". In 2021 Third International Conference on Intelligent Communication Technologies and Virtual Mobile Networks (ICICV). IEEE, 2021. http://dx.doi.org/10.1109/icicv50876.2021.9388537.

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Elisseyeva, I. S., I. G. Giorgadze, N. N. Kodzhebash, E. S. Kojevnicova, V. V. Nasedkin, V. N. Shuval-Sergeyev e K. A. Jovinski. "Some Problems Can Be Solved by the QSP-Method". In 59th EAGE Conference & Exhibition. European Association of Geoscientists & Engineers, 1997. http://dx.doi.org/10.3997/2214-4609-pdb.131.gen1997_p191.

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S. Elysseieva, I., N. P. Zvetkova, V. V. Nasedkin e R. V. Lobzova. "The QSP method for investigation of Baltic Shield and Barents Sea Shelf". In 55th EAEG Meeting. European Association of Geoscientists & Engineers, 1993. http://dx.doi.org/10.3997/2214-4609.201411689.

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Wilkins, A. Katharina, Andrew Matteson, Lore Gruenbaum, Jennifer Park, John M. Burke e Joshua F. Apgar. "Abstract 4266: Computational exploration of mechanistic determinants of ADC pharmacokinetics using QSP modeling strategies". In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-4266.

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S. Elysseïeva, I. "Technique of Operative Revealing of Rock Solidity Sites for Nuclear Wastes Burial by the QSP-Method Updating". In 60th EAGE Conference and Exhibition. European Association of Geoscientists & Engineers, 1998. http://dx.doi.org/10.3997/2214-4609.201408358.

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Lili, Liu, Zhang Ming e Deng Jian. "Analysis of RCS Depressurization Effects on Containment Temperature for Qinshan Phase II Nuclear Power Plant". In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30649.

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A severe accident code was applied for modeling of a typical pressurized water reactor (PWR) nuclear power plant, and the effects of RCS depressurization on the gas temperature of the relief tank cell in the containment during a station blackout (SBO) induced accident was analyzed. The sensitivity calculation indicated that the hydrogen generation rate obviously increased due to RCS depressurization in a critical stage. The results show that RCS depressurization can play an important role in hydrogen generation rate and total accumulation, and the temperature of the containment atmosphere is highly influenced by hydrogen combustion. High temperature induced by hydrogen combustion may degrade the equipment and instruments capabilities. Based on this analysis, a feasible strategy of RCS depressurization for mitigating the accident consequence is provided for developing the capacity of the SBO treatment of Qinshan Phase Nuclear Power Plant (QSP-II NPP).

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Pierre, Kamau, Lin Lin, Lore Gruenbaum, Carissa Young, Joshua Apgar, Christian Hotz, Timothy Wagenaar e Spyros K. Stamatelos. "Abstract 685: Development of a multiscale QSP model to characterize the tumor suppressive effects of a cytokine mRNA immunotherapy in a preclinical melanoma mouse model". In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-685.

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Johnson, Kaitlyn E., Maria Veronica Ciocanel, Josua Aponte, Nicolas Bajeux, Fanwang Meng e Dean Bottino. "Abstract 231: Evaluation of pharmacologic mechanisms to overcome IgG1 antibody (Ab) resistance via quantitative systems pharmacology (QSP) modeling of antibody-dependent cell mediated cytotoxicity (ADCC)". In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-231.

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DARSHANI, CHARIKA, K. I. RIDMIKA e B. A. K. S. PERERA. "LIFE MANAGEMENT OF CONTRACTOR’S SITE QUANTITY SURVEYOR". In 13th International Research Conference - FARU 2020. Faculty of Architecture Research Unit (FARU), University of Moratuwa, 2020. http://dx.doi.org/10.31705/faru.2020.11.

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Life management controls the quality of one’s work while ensuring one’s quality of life with minimum conflicts. The contractor’s site quantity surveyor (QS), who has to shoulder many responsibilities on-site amongst time constraints, can most probably experience a life imbalance. Because the personal responsibilities of female and male site QSs differ, the aim of this study was to identify the strategies that will enhance the life management of contractor’s site quantity surveyors. The qualitative approach was adopted in the study, and the required empirical data were collected by interviewing 20 females and 20 males contractor’s site QSs. The interview findings were analysed using manual content analysis. Thirty-one and twenty-eight causes of life imbalance in male and female QSs respectively were identified. In addition, 50 and 48 strategies that will facilitate satisfactory life management in male and female QSs, respectively were identified. Some of the identified causes and strategies were common to both male and females QSs.

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Rapporti di organizzazioni sul tema "Qsp"

Hausel, J. M. Questionnaire for sensitive positions (QSP) version 4.0 -- Users guide document. Office of Scientific and Technical Information (OSTI), maggio 1996. http://dx.doi.org/10.2172/251338.

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Sherlock, R. L., e D. W. Lindsay. Volcanic stratigraphy of the QSP area, Hope Bay volcanic belt, Nunavut. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2002. http://dx.doi.org/10.4095/213182.

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Hartman, Andrea, William Long e Lisa Veitch. Quiet Supersonic Platform (QSP) Materials and Structures Focus Group Meeting, 26 June 2001. Fort Belvoir, VA: Defense Technical Information Center, luglio 2001. http://dx.doi.org/10.21236/ada408538.

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Comstock, John, e Wallace Eakes. Qualified Recycling Program (QRP) Guide. Fort Belvoir, VA: Defense Technical Information Center, luglio 2000. http://dx.doi.org/10.21236/ada381043.

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Chen, Jie, Robert Edwards e William Watson. QMP: LQCD Message Passing API. Office of Scientific and Technical Information (OSTI), marzo 2003. http://dx.doi.org/10.2172/808810.

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Mills, Jeffrey D. IL QC QSPR - Preliminary Results. Fort Belvoir, VA: Defense Technical Information Center, febbraio 2004. http://dx.doi.org/10.21236/ada422511.

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Edwards, Robert. QDP++: Data Parallel Interface for QCD. Office of Scientific and Technical Information (OSTI), marzo 2003. http://dx.doi.org/10.2172/808809.

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Reiersen, W., P. Heitzenroeder, G. Neilson, B. Nelson, M. Zarnstorff, T. Brown, M. Cole et al. Progress In NCSX and QPS Design and Construction. Office of Scientific and Technical Information (OSTI), ottobre 2005. http://dx.doi.org/10.2172/899587.

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Gillen, Emily, Olivia Berzin, Adam Vincent e Doug Johnston. Certified Electronic Health Record Technology Under the Quality Payment Program. RTI Press, gennaio 2018. http://dx.doi.org/10.3768/rtipress.2018.pb.0014.1801.

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The 2016 Quality Payment Program (QPP) is a Medicare reimbursement reform designed to incentivize value-based care over volume-based care. A core tenet of the QPP is integrated utilization of certified electronic health record technology (CEHRT). Adopting and implementing CEHRT is a resource-intensive process, requiring both financial capital and human capital (in the form of knowledge and time). Adoption can be especially challenging for small or rural practices that may not have access to such capital. In this issue brief, we discuss the role of CEHRT in the QPP and offer policy recommendations to help small and rural practices improve their health information technology (IT) capabilities with regards to participation in value-based care. The QPP requires practices to have health IT capabilities, both as a requirement for a complete performance score and to facilitate reporting. Practices that are unable to implement CEHRT will have difficulty complying with the new reimbursement system, and will likely incur financial losses. We recommend monetary support and staff training to small and rural practices for the adoption of CEHRT, and we recommend assistance to help practices comply with the requirements of the QPP and coordinate with other small and rural practices for reporting purposes.

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THOMAS, W. K. AZ-101 Mixer Pump Test Qualification Test Procedures (QTP). Office of Scientific and Technical Information (OSTI), gennaio 2000. http://dx.doi.org/10.2172/801140.

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