Accedi

Bibliografie tematiche / Sodium/calcium exchanger (NCX) / Tesi

Segui questo link per vedere altri tipi di pubblicazioni sul tema: Sodium/calcium exchanger (NCX).

Tesi sul tema "Sodium/calcium exchanger (NCX)"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 18 febbraio 2022

Cita una fonte nei formati APA, MLA, Chicago, Harvard e in molti altri stili

Scegli il tipo di fonte:

Vedi i top-23 saggi (tesi di laurea o di dottorato) per l'attività di ricerca sul tema "Sodium/calcium exchanger (NCX)".

Accanto a ogni fonte nell'elenco di riferimenti c'è un pulsante "Aggiungi alla bibliografia". Premilo e genereremo automaticamente la citazione bibliografica dell'opera scelta nello stile citazionale di cui hai bisogno: APA, MLA, Harvard, Chicago, Vancouver ecc.

Puoi anche scaricare il testo completo della pubblicazione scientifica nel formato .pdf e leggere online l'abstract (il sommario) dell'opera se è presente nei metadati.

Vedi le tesi di molte aree scientifiche e compila una bibliografia corretta.

1

Jeffs, Graham J. "The effect of sodium/calcium exchanger 3 (NCX3) knockout on neuronal survival following global cerebral ischaemia in mice." University of Western Australia. School of Biomedical, Biomolecular and Chemical Sciences, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0063.

Testo completo

Abstract (sommario):

Cerebral ischaemia is a leading cause of disability and death world-wide. The only effective treatments are thrombolytic therapy (plasminogen activator; tPA) and hypothermia (33?C). However, tPA has limited clinical application due to its short therapeutic time window and its specific application in thrombo-embolic stroke. Moderate hypothermia (33?C) is only being used following cardiac arrest in comatose survivors. Hence more treatments are urgently required. The first step in developing new treatments is the identification and characterisation of a potential therapeutic target. Since brain d

Gli stili APA, Harvard, Vancouver, ISO e altri

2

Reilly, Louise. "Palmitoylation of the cardiac sodium-calcium exchanger." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/37d8a92d-1536-4a05-85f6-a45f9c41a489.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

3

Sher, Anna. "Modelling local calcium dynamics and the sodium/calcium exchanger in ventricular myocytes." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670114.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

4

Bossuyt, Julie. "Sodium-calcium exchange and caveolins." MU has:, 2002. http://wwwlib.umi.com/cr/mo/fulltext?p3052149.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

5

Han, C. (Chunlei). "Intracellular calcium stores and sodium-calcium exchanger in cardiac myocytes:experimental and computer simulation study." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514265912.

Testo completo

Abstract (sommario):

Abstract Cytosolic Ca2+, [Ca2+]I , has a key role in intracellular signalling during excitation-contraction coupling (E-C coupling) in cardiac myocytes. The sarcoplasmic reticulum (SR) is a main intracellular Ca2+ store and the Na+-Ca2+ exchanger (NaCaX) is a major mechanism to extrude Ca2+ for balancing the Ca2+ influx via L-type Ca2+ channels during excitation. Furthermore, [Ca2+]I also affects the configuration of the action potential (AP). The present study, by combination of animal experiments and computer simulations, investigated the roles of [Ca2+]I, SR and NaCaX in car

Gli stili APA, Harvard, Vancouver, ISO e altri

6

Hung, Hsiao-Yu. "Spatial organization of sodium calcium exchanger and caveolin-3 in developing mammalian ventricular cardiomyocytes." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/791.

Testo completo

Abstract (sommario):

In adult cardiomyocytes, the established mechanism of excitation-contraction coupling is calcium-induced calcium release (CICR) mediated by L-type Ca2+ channels (Cav1.2). Briefly, membrane depolarization opens voltage-gated Cav1.2 to allow for the influx of extracellular Ca2+ into the cytosol. This small sarcolemmal (SL) Ca2+ influx is necessary for triggering a larger release of Ca2+ from the intracellular Ca2+ storage site, the sarcoplasmic reticulum (SR), through the SR Ca2+ release channel also known as the ryanodine receptor (RyR). RyR-mediated release of SR Ca2+ effectively raises the

Gli stili APA, Harvard, Vancouver, ISO e altri

7

Modgi, Amol Polo-Parada Luis. "The role of sodium-calcium exchanger in the electrical activity of embryonic chicken heart." Diss., Columbia, Mo. : University of Missouri--Columbia, 2008. http://hdl.handle.net/10355/6671.

Testo completo

Abstract (sommario):

The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on September 25, 2009). Thesis advisor: Dr. Luis Polo Parada. Includes bibliographical references.

Gli stili APA, Harvard, Vancouver, ISO e altri

8

Elliott, Elspeth B. A. "Investigation of factors affecting the sodium/calcium exchanger in a rabbit model of left ventricular dysfunction." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433518.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

9

Guan, Yinzheng. "Blebbistatin Protects Rodent Myocytes from Death in Primary Culture via Inhibiting the Sodium/ Calcium Exchanger and the L-type Calcium Channel." Master's thesis, Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/150014.

Testo completo

Abstract (sommario):

Physiology<br>M.S.<br>Introduction: Cardiac disease is a leading cause of mortabity and morbidity in the developed countries. Cultured cardiac myocytes are widely used for exploring the underlying pathophysiology of cardiac disease. Rodents, especially mice with transgenes or gene ablation, have become popular animal models for heart disease research. However, it has been long recognized that rodent myoyctes die during long-term primary culture, which limits the use of genetically altered myocytes for signaling studies. Blebbistatin (BLB), a myosin II ATPase inhibitor, has been used to protect

Gli stili APA, Harvard, Vancouver, ISO e altri

10

Yuan, Jiaqi. "Investigations of macromolecules and small biomolecules by solution NMR: applications to the intracellular loop structure of the sodium-calcium exchanger and metabolite identification methods." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1542630633935356.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

11

Nguidjoe, Evrard. "Etude de la fonction de la cellule bêta pancréatique dans un modèle de souris présentant une mutation nulle partielle de l'échangeur sodium/calcium." Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209833.

Testo completo

Abstract (sommario):

Précédemment, nous avons montré que la surexpression de l'échangeur Na/Ca NCX1), une protéine responsable de la sortie de calcium (Ca2+) des cellules, augmentait la mort cellulaire programmée ou « apoptose » et réduisait la prolifération des cellules β. Afin d’étudier plus en profondeur le rôle de l’échangeur dans les cellules β in vivo, nous avons développé et caractérisé des souris présentant une inactivation de NCX1.<p>Des méthodes biologiques et morphologiques (imagerie du Ca2+, capture de Ca2+, métabolisme du glucose, sécrétion d'insuline et morphométrie par comptage de points) ont été ut

Gli stili APA, Harvard, Vancouver, ISO e altri

12

Vierheller, Janine. "Modelling excitation coupling in ventricular cardiac myocytes." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19158.

Testo completo

Abstract (sommario):

Um die Kontraktion einer Herzmuskelzelle durch den Kalziumeinstrom zu ermöglichen, ist die Kopplung von Erregung und Kontraktion (ECC) von zentraler Bedeutung. Durch das elektrische Signal einer Nachbarzelle wird die Depolarisation des Sarkolemmas verursacht, wodurch sich die L-Typ-Kalziumkanäale (LKK) öffnen und der Amplifizierungsprozess eingeleitet wird. Letzterer ist bekannt als Kalzium induzierte Kalzium Freisetzung (CICR). Durch die LKK wird ein Kalziumeinstrom in die Zelle ermöglicht, welcher zur Öffnung der Ryanodinrezeptoren (RyR) des Sarkoplasmatischen Retikulums (SR) führt. D

Gli stili APA, Harvard, Vancouver, ISO e altri

13

de, Moissac Danielle. "Structure-function studies of the sodium-calcium exchanger isoforms, NCX1 and NCX2." 2009. http://hdl.handle.net/1993/3158.

Testo completo

Abstract (sommario):

The sodium-calcium exchanger (NCX) is a countertransporter of Na+ and Ca2+ across most cell membranes. It has been identified as an essential component of Ca2+ homeostasis in physiological and disease conditions in both cardiovascular and neurological settings. The exchanger not only transports Na+ and Ca2+, but is also regulated by these ions. Although ionic regulatory profiles differ between NCX isoforms, similar regulatory domains have been identified. Previous structure-function studies have determined key residues within these domains, particularly in the eXchanger Inhibitory Peptide reg

Gli stili APA, Harvard, Vancouver, ISO e altri

14

Chen, Shao-Hong, and 陳紹弘. "A Study of the Sodium Calcium Ion Exchange Mechanism in NCX." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/06903241036428583046.

Testo completo

Abstract (sommario):

碩士<br>國立新竹教育大學<br>應用數學系碩士班<br>103<br>Biological sodium calcium ion exchange channel (NCX) removes calcium ions very rapidly from cell inside in exchange with sodium ions from outside. The Poisson-Fermi theory is used to analyze the binding potentials of NCX. It allows us to mathematically investigate the sodium-calcium ion exchange mechanism in NCX. Numerical results have been shown to agree with the experimental results of the sodium-calcium ion exchange.

Gli stili APA, Harvard, Vancouver, ISO e altri

15

Schwarz, Erich Marquard. "Calx, A Sodium-Calcium Exchanger of Drosophila melanogaster." Thesis, 1996. https://thesis.library.caltech.edu/11872/12/schwarz-em-1996.pdf.

Testo completo

Abstract (sommario):

<p>Calcium extrusion is necessary for cellular survival and suspected to modulate cellular activity. <i>Drosophila</i> phototransduction is a promising system in which to study calcium export, since it is dominated by calcium activity yet, unlike most calcium-dependent signalling pathways, genetically pliable. The multiple roles of calcium flux in <i>Drosophila</i> phototransduction are reviewed in Chapter One.</p> <p><i>Calx</i>, a <i>Drosophila</i> ortholog of mammalian 3Na<sup>+</sup>/1Ca<sup>2+</sup> exchangers, was isolated and characterized (Chapter Two). <i>Calx</i>'s gene product ha

Gli stili APA, Harvard, Vancouver, ISO e altri

16

Yang, Ya-Chi, and 楊雅琪. "Regulation of Sodium-Calcium Exchanger Activity by Creatine Kinase." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/17885972289537598732.

Testo completo

Abstract (sommario):

博士<br>國立陽明大學<br>生化暨分子生物研究所<br>98<br>Abstract Na+/Ca2+ exchanger (NCX) is one of the major mechanisms for removing Ca2+ from the cytosol especially in cardiac myocytes and neurons, where their physiological activities are triggered by an influx of Ca2+. NCX contains a large intracellular loop (NCXIL) that is responsible for regulating NCX activity. Recent evidence has shown that proteins, including kinases and phosphatases, associate with NCX1IL to form a NCX1 macromolecular complex. To search for the molecules that interact with NCX1IL and regulate NCX1 activity, we used the yeast two-hybr

Gli stili APA, Harvard, Vancouver, ISO e altri

17

Chen, Lih-Woan, and 陳麗婉. "Presence of Sodium-Calcium Exchanger in Bovine Chromaffin Cells." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/50026187259025119413.

Testo completo

Abstract (sommario):

碩士<br>國立陽明大學<br>生物化學研究所<br>87<br>Calcium ion plays important roles in many physiological reactions. It is therefore important to understand how cells regulate their intracellular calcium concentration ([Ca2+ ]i). We have used bovine adrenal chromaffin cells as a model system to study the regulation of [ Ca2+ ]i. Previous results from our laboratory have shown that Na+/Ca2+ exchanger is the major mechanism that is responsible for removing Ca2+ from the cytosol and bringing the [ Ca2+ ]i to the resting level, after the [ Ca2+ ]i is increased by an influx of extracellular Ca2+. There are two

Gli stili APA, Harvard, Vancouver, ISO e altri

18

Brittain, Matthew K. "THE ROLE OF THE NMDA RECEPTOR AND REVERSE SODIUM CALCIUM EXCHANGER IN CALCIUM DYSREGULATION IN GLUTAMATE-EXPOSED NEURONS." Thesis, 2012. http://hdl.handle.net/1805/3042.

Testo completo

Abstract (sommario):

Indiana University-Purdue University Indianapolis (IUPUI)<br>Introduction: During glutamate excitotoxicity, overstimulation of glutamate receptors leads to sustained elevation in cytosolic Ca2+ ([Ca2+]c), or delayed Ca2+ dysregulation (DCD), which is causally linked to cell death. There are two major hypothetical mechanisms for DCD: the continuous activation of N-methyl-D-aspartate-subtype of the ionotropic glutamate receptors (NMDAR) and the reversal of the plasmalemmal Na+/Ca2+ exchanger. However, the contribution of each of these mechanisms in DCD is not completely established. Major re

Gli stili APA, Harvard, Vancouver, ISO e altri

19

Xu, Li-Song, and 許立松. "Characteriztation of sodium-calcium exchanger activity in neuroblastoma x glioma hybrid NG108-15 cells." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/63476016161848014396.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

20

Pellman, Jessica J. "Regulation of neuronal calcium homeostasis in Huntington's." Diss., 2015. http://hdl.handle.net/1805/10975.

Testo completo

Abstract (sommario):

Indiana University-Purdue University Indianapolis (IUPUI)<br>Huntington’s Disease (HD) is an inherited, autosomal dominant, neurodegenerative disorder. There is no cure for HD and the existing therapies only alleviate HD symptoms without eliminating the cause of this neuropathology. HD is linked to a mutation in the huntingtin gene, which results in an elongation of the poly-glutamine stretch in the huntingtin protein (Htt). A major hypothesis is that mutant Htt (mHtt) leads to aberrant Ca2+ homeostasis in affected neurons. This may be caused by increased Ca2+ influx into the cell via the N-me

Gli stili APA, Harvard, Vancouver, ISO e altri

21

Hussain, Munir, and A. Chorvatova. "Effects of caffeine on potassium currents in isolated rat ventricular myocytes." 2009. http://hdl.handle.net/10454/3003.

Testo completo

Abstract (sommario):

No<br>Rapid exposure of cardiac muscle to high concentrations of caffeine releases Ca 2+ from the sarcoplasmic reticulum (SR). This Ca 2+ is then extruded from the cell by the Na +/Ca 2+ exchanger. Measurement of the current carried by the exchanger ( I Na/Ca) can therefore be used to estimate of the Ca 2+ content of the SR. Previous studies have shown that caffeine, however, can also inhibit K + currents. We therefore investigated whether the inhibitory effects of caffeine on these currents could contaminate measurements of I Na/Ca. Caffeine caused partial inhibition of the inward rectifier K

Gli stili APA, Harvard, Vancouver, ISO e altri

22

Soliman, Daniel. "Ion transport pharmacology in heart disease and type-2 diabetes." Phd thesis, 2010. http://hdl.handle.net/10048/1629.

Testo completo

Abstract (sommario):

The cardiac sodium-calcium exchanger (NCX) is an important membrane protein which regulates cellular calcium necessary for the optimal contractile function of the heart. NCX has become a focal point in ischemic heart disease (IHD) research as evidence suggests that reactive oxygen species (ROS) produced during IHD can cause NCX to malfunction resulting in an intracellular calcium overload leading to cardiac contractile abnormalities. Therefore, I hypothesized that NCX function is mediated by ROS increasing NCX1 activity during cardiac ischemia-reperfusion. To research this hypothesis, I invest

Gli stili APA, Harvard, Vancouver, ISO e altri

23

Bellmann, Sarah. "Die Bedeutung der Ca2+/Calmodulin-abhängigen Proteinkinase IIδ für die zytosolische Natrium- und Kalziumüberladung sowie Arrhythmogenese in Herzmuskelzellen". Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-000D-F0E3-D.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

Offriamo sconti su tutti i piani premium per gli autori le cui opere sono incluse in raccolte letterarie tematiche. Contattaci per ottenere un codice promozionale unico!