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Letteratura scientifica selezionata sul tema "Stage-specific framework"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 10 febbraio 2022

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Articoli di riviste sul tema "Stage-specific framework"

Hayes, Daniel, Miguel Moreira, Isabel Boavida, Melanie Haslauer, Günther Unfer, Bernhard Zeiringer, Franz Greimel, Stefan Auer, Teresa Ferreira, and Stefan Schmutz. "Life Stage-Specific Hydropeaking Flow Rules." Sustainability 11, no. 6 (March 14, 2019): 1547. http://dx.doi.org/10.3390/su11061547.

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Peak-operating hydropower plants are usually the energy grid’s backbone by providing flexible energy production. At the same time, hydropeaking operations are considered one of the most adverse impacts on rivers, whereby aquatic organisms and their life-history stages can be affected in many ways. Therefore, we propose specific seasonal regulations to protect ecologically sensitive life cycle stages. By reviewing hydropeaking literature, we establish a framework for hydrological mitigation based on life-history stages of salmonid fish and their relationship with key parameters of the hydrograp

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Mancini, Stephen, Laurie Iacono, Frank Hartle, Megan Garfinkel, Dana Horn, and Alison Sullivan. "Introducing the Common Attack Process Framework for Incident Mapping." International Journal of Cyber Research and Education 3, no. 2 (July 2021): 20–27. http://dx.doi.org/10.4018/ijcre.2021070102.

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The paper presents a new framework that allows both educators and operational personnel to better overlay incidents into a simplified framework. While other attack frameworks exist, they either lack simplicity or are too focused on specific types of attacks. Therefore, the authors have attempted to define a framework that can be used broadly across both physical and cyber incidents. Furthermore, the paper provides several high-profile examples wherein it is shown how this new framework more accurately represents the adversary's actions. Lastly, the framework allows room for expansion in that,

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van der Meij, Barbara S., Coline P. Schoonbeek, Egbert F. Smit, Maurizio Muscaritoli, Paul A. M. van Leeuwen, and Jacqueline A. E. Langius. "Pre-cachexia and cachexia at diagnosis of stage III non-small-cell lung carcinoma: an exploratory study comparing two consensus-based frameworks." British Journal of Nutrition 109, no. 12 (November 16, 2012): 2231–39. http://dx.doi.org/10.1017/s0007114512004527.

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Despite the development of consensus-based frameworks to define cancer cachexia, the validity and usefulness of these frameworks are relatively unknown. The aim of the present study was to study the presence of pre-cachexia and cachexia in patients with stage III non-small-cell lung carcinoma (NSCLC) by using a cancer-specific framework and a general framework for cachexia, and to explore the prognostic value of pre-cachexia and cachexia. In forty patients at diagnosis of stage III NSCLC, weight loss, fat-free mass, handgrip strength, anorexia and serum biochemistry, assessed before the first

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Yadav, Gunjan, Dinesh Seth, and Tushar N. Desai. "Analysis of research trends and constructs in context to lean six sigma frameworks." Journal of Manufacturing Technology Management 28, no. 6 (July 3, 2017): 794–821. http://dx.doi.org/10.1108/jmtm-03-2017-0043.

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Purpose The literature of lean six sigma (LSS) is flooded with frameworks. But to date, there has been no attempt to expose the inconsistencies in the existing frameworks and associated research trends. The purpose of this paper is to critically review 26 LSS frameworks and highlight inconsistencies. The study also helps in analysing research trends and constructs of LSS frameworks, and facilitates new applications. Design/methodology/approach It uses Scopus database and finalises 26 frameworks in the LSS domain considering a timeframe from 2000 to 2017, using a structured literature review ap

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Saarela, Martti, Anna-Mari Simunaniemi, Matti Muhos, and Pekka Leviäkangas. "Growth management of eHealth service start-ups." Journal of Advances in Management Research 15, no. 1 (February 5, 2018): 17–36. http://dx.doi.org/10.1108/jamr-06-2017-0073.

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Purpose The purpose of this paper is to focus on the early development of eHealth service start-ups. To elaborate the research problem, the study addresses the following research questions: How do managerial experiences in eHealth service start-ups relate to the central findings of the recent empirically based stages-of-growth literature? What context-specific viewpoints should be considered when using the stage framework in relation to eHealth service start-ups? Design/methodology/approach In this explorative multiple case study, the authors test a growth framework describing the early stages

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Ota, Helen C. U., Brandon G. Smith, Alexander Alamri, Faith C. Robertson, Hani Marcus, Allison Hirst, Marike Broekman, Peter Hutchinson, Peter McCulloch, and Angelos Kolias. "The IDEAL framework in neurosurgery: a bibliometric analysis." Acta Neurochirurgica 162, no. 12 (July 10, 2020): 2939–47. http://dx.doi.org/10.1007/s00701-020-04477-5.

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Abstract Background The Idea, Development, Exploration, Assessment and Long-term study (IDEAL) framework was created to provide a structured way for assessing and evaluating novel surgical techniques and devices. Objectives The aim of this paper was to investigate the utilization of the IDEAL framework within neurosurgery, and to identify factors influencing implementation. Methods A bibliometric analysis of the 7 key IDEAL papers on Scopus, PubMed, Embase, Web of Science, and Google Scholar databases (2009–2019) was performed. A second journal-specific search then identified additional papers

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Amaldass, Nareyus, Cormac Lucas, and Nenad Mladenovic. "A heuristic hybrid framework for vector job scheduling." Yugoslav Journal of Operations Research 27, no. 1 (2017): 31–45. http://dx.doi.org/10.2298/yjor150416013a.

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We examine the first phase of a known NP-hard 2-stage assembly problem. It consists of sequencing a set of jobs having multiple components to be processed. Each job has to be worked on independently on a specific machine. We consider these jobs to form a vector of tasks. Our objective is to schedule jobs on the particular machines in order to minimize the completion time before the second stage starts. We first develop a new mathematical programming formulation of the problem and test it on a small problem instance using an integer programming solver. Then, we develop a heuristic algorithm bas

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Corbo, Leonardo, Shadi Mahassel, and Alberto Ferraris. "Translational mechanisms in business model design: introducing the continuous validation framework." Management Decision 58, no. 9 (May 30, 2020): 2011–26. http://dx.doi.org/10.1108/md-10-2019-1488.

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PurposeThis paper aims at proposing knowledge translation as an element of business model design that can support entrepreneurs in achieving alignment and collaboration between entrepreneurial teams and external stakeholders.Design/methodology/approachThe conceptual model presented in the paper is developed from the literature review and draws mainly on two streams of work as follows: first, the contributions related to the lean start-up methodology initially developed by Blank and Ries and second, the work of Osterwalder and Pigneur on business models and its subsequent developments. In addit

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McLean, Richard Scott, and Jiju Antony. "A conceptual continuous improvement implementation framework for UK manufacturing companies." International Journal of Quality & Reliability Management 34, no. 7 (August 7, 2017): 1015–33. http://dx.doi.org/10.1108/ijqrm-02-2016-0022.

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Purpose The purpose of this paper is to review current continuous improvement implementation models and frameworks, and present a new conceptual framework tailored specifically to the needs of UK manufacturing companies. Design/methodology/approach The paper details the in-depth review of 20 existing models or frameworks for continuous improvement implementation, demonstrating the need for a new industry and region specific solution. Through the incorporation of previous findings from literature, coupled with the positive aspects of the current offerings, a new conceptual framework for continu

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Wiese, Lisa, Anna E. Pohlmeyer, and Paul Hekkert. "Design for Sustained Wellbeing through Positive Activities—A Multi-Stage Framework." Multimodal Technologies and Interaction 4, no. 4 (September 29, 2020): 71. http://dx.doi.org/10.3390/mti4040071.

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In this paper, we introduce a framework that conceptualizes a multi-stage process through which technology can promote sustained wellbeing. Intentional wellbeing-enhancing activities form the centerpiece linking direct product interaction to, ultimately, wellbeing. The framework was developed following a bottom-up–top-down approach by integrating theoretical knowledge from positive psychology, behavioral science and human–computer interaction (HCI)/design with empirical insights. We outline (a) the framework, (b) its five main stages including their multidisciplinary theoretical foundations, (

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Più fonti

Tesi sul tema "Stage-specific framework"

Gravuer, Kelly. "Determinants of the introduction, naturalisation, and spread of Trifolium species in New Zealand." Master's thesis, Lincoln University. Bio-Protection and Ecology Division, 2004. http://theses.lincoln.ac.nz/public/adt-NZLIU20071015.060329/.

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Two conceptual approaches which offer promise for improved understanding of biological invasions are conceptualizing the invasion process as a series of distinct stages and explicitly incorporating human actions into analyses. This study explores the utility of these approaches for understanding the invasion of Trifolium (true clover) species in New Zealand. From the published literature, I collected a range of Trifolium species attributes, including aspects of global transport and use by humans, opportunistic association with humans in New Zealand, native range attributes, habitat character

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Libri sul tema "Stage-specific framework"

Oakes, Lisa M., and David H. Rakison. Developmental Cascades. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780195391893.001.0001.

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Children take their first steps, produce their first words, and become able to solve many new problems seemingly overnight. Yet, each change reflects many other previous developments that occurred in the whole child across a range of domains, and each change, in turn, will provide opportunities for future development. This book proposes that all change can be explained in terms of developmental cascades such that events that occur at one point in development set the stage, or cause a ripple effect, for the emergence or development of different abilities, functions, or behaviors at another poin

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Arent, Douglas, Channing Arndt, Mackay Miller, Finn Tarp, and Owen Zinaman, eds. The Political Economy of Clean Energy Transitions. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198802242.001.0001.

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The 21st Conference of the Parties (CoP21) to the United Nations Framework Convention on Climate Change (UNFCCC) shifted the nature of the political economy challenge associated with achieving a global emissions trajectory that is consistent with a climate. The shifts generated by CoP21 place country decision-making and country policies at centre stage. Under moderately optimistic assumptions concerning the vigour with which CoP21 objectives are pursued, nearly every country in the world will set about to design and implement the most promising and locally relevant policies for achieving their

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Richard, Kreindler, Wolff Reinmar, and Rieder Markus S. Commercial Arbitration in Germany. Oxford University Press, 2016. http://dx.doi.org/10.1093/law/9780199676811.001.0001.

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This book provides a detailed commentary on and analysis of German arbitration law and practice. This title covers both domestic and international arbitration in all its stages. The work details the legal framework for German-related arbitration and provides practical guidance on the appropriate choices, with a specific focus on particularities of German law and practice. The book navigates along the life cycle of an arbitration, commencing with the arbitration agreement, continuing with the arbitral tribunal, the arbitral proceedings and interim relief, and concluding with the arbitral award

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Capitoli di libri sul tema "Stage-specific framework"

Reimers, Fernando M. "The Role of Universities Building an Ecosystem of Climate Change Education." In Education and Climate Change, 1–44. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-57927-2_1.

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AbstractThis chapter introduces the field of climate change education, noting the paradox that in spite of many efforts at incorporating climate change in education policy and curriculum frameworks, and a diversity of practices in schools, there is little evidence that such efforts are contributing to adaptation, mitigation or reversal of climate change. The chapter reviews the role of international development organizations advocating for and developing frameworks in support of climate change education. This is followed by an analysis of ongoing efforts of climate change education.The chapter argues that more effective education for climate change at the primary and secondary education levels around the world requires context specific strategies that align the specific learning outcomes with the impacts of climate change in that context. Implementing those strategies requires the development of institutional capacity in schools that is aligned to the stage of institutional development of the school. The chapter explains how a multidisciplinary framework that accounts for the cultural, psychological, professional, institutional and political dimensions of the change process can support the development of collaboration and coherence in implementing those climate change education strategies. Those strategies need to also specify the particular populations that need to develop such competencies and the optimal means of delivery. The chapter also situates the literature on climate change education within the larger context of the literature on deeper learning, twenty first century skills and education system change, explaining how deeper learning in climate change education might influence attitudes and behaviors in ways that prevailing didactic approaches focused principally on the transmission of scientific knowledge do not.To develop such context specific climate change education strategies and to build the institutional capacity to implement them, the chapter makes the case for more intentional engagement of universities, in partnership with schools and non-formal education organizations. This would serve the dual role of providing support for schools in advancing climate change education, while also educating higher education students on climate change through problem based, participatory and contextually situated approaches.

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Verstraete, Jonas, Freya Acar, Grazia Concilio, and Paola Pucci. "Turning Data into Actionable Policy Insights." In The Data Shake, 73–89. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63693-7_6.

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AbstractIt is becoming clearer that data-supported input is essential in the policy making process. But at which point of the process, and in which format, can data aid policy making? And what does an organisation need to turn data into relevant insights? This paper explores the role of data from two perspectives. In the first part, data and data analysis are situated in the policy making process by mapping them onto the data supported policy making model and highlighting the different roles they can assume in each stage and step of the process. The second part discusses a practical framework for policy-oriented data activities, zooming in on the data-specific actions and the actors performing them in each data-supported step of the policy making process. We observe that a close collaboration between the policy maker and data scientist in the framework of an iterative approach permits to transform the policy question into a suited data analysis question and deliver relevant insights with the flexibility desired by decision makers. In conclusion, for data to be turned into actionable policy insights it is vital to set up structures that ensure the presence and the collaboration of policy-oriented and data-oriented competences.

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"Evaluation of IT Governance in Middle East and North African Large Organizations." In Advances in Business Information Systems and Analytics, 92–136. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-7826-0.ch003.

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This chapter provides a deeper understanding of IT governance frameworks and their adoption, drawing on established information systems theories. A mixed two-stage approach using quantitative and qualitative studies is used to examine the feasibility of developing an IT governance assessment framework based on COBIT to assess IT governance in a specific context. The first step seeks to identify key COBIT best practices within organizations. A survey of 20 large organizations in the MENA region was adopted. In the second phase, a case study used to explore the factors that influence the adoption of the adapted IT governance assessment framework.

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Khan, Umraz, Graeme Perks, Rhidian Morgan-Jones, Peter James, Colin Esler, Vince Smyth, and Vanya Gant. "Specific microbiology issues relating to prosthetic joint infection." In Pathways in Prosthetic Joint Infection, 41–50. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198791881.003.0007.

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This chapter discusses specific microbiology issues relating to prosthetic joint infection (PJI) and includes discussion on antibiotic prophylaxis (including elective joint replacement in the uninfected case), choice of ‘prophylaxis/treatment’ in the infected, or presumed, infected case, a suggested framework for a safe practice, antibiotic use in PJI in the age of resistance, background on rising antibiotic resistance, approach to one- and two-stage surgical management, outpatient antibiotic therapy and when to use it, monitoring/stopping rules, the particular problems of Pseudomonas and Candida in PJI, and myths and facts about what ‘immunosuppression’ actually means in practice (including MRSA), and a conclusion.

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Muralidharan, Etayankara, and Saurav Pathak. "Home Country Institutions and International Entrepreneurship." In Handbook of Research on Approaches to Alternative Entrepreneurship Opportunities, 291–314. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1981-3.ch014.

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The extent of internationalization by early-stage entrepreneurial firms may depend upon home country institutional conditions. Using insights from institutional theory, this chapter suggests that national-level institutional conditions facilitate or constrain the efforts made by early-stage entrepreneurs to internationalize. Given the strong linkages between entrepreneurs and the enterprises they drive, the multi-level framework proposed in this study suggests that a strong national system of innovation and better regulatory quality, which supports early internationalization by new entrepreneurial firms. Smaller domestic markets induce such firms to explore overseas markets for their products. The framework also suggests that a strong regulatory environment positively moderates the effects of national innovation systems and domestic market size on the extent of early internationalization. While implications for the internationalization process are discussed, specific reference to the importance of policy to support internationalization by early entrepreneurial firms is made.

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Lee, One-Ki ("Daniel"), Mo ("Winnie") Wang, Kai H. Lim, and Zeyu ("Jerry") Peng. "Knowledge Management Systems Diffusion in Chinese Enterprises." In Information Resources Management, 1370–85. IGI Global, 2010. http://dx.doi.org/10.4018/978-1-61520-965-1.ch424.

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With the recognition of the importance of organizational knowledge management (KM), researchers have paid increasing attention to knowledge management systems (KMS). However, since most prior studies were conducted in the context of Western societies, we know little about KMS diffusion in other regional contexts. Moreover, even with the increasing recognition of the influence of social factors in KM practices, there is a dearth of studies that examine how unique social cultural factors affect KMS diffusion in specific countries. To fill in this gap, this study develops an integrated framework, with special consideration on the influence of social cultures, to understand KMS diffusion in Chinese enterprises. In our framework, we examine how specific technological, organizational, and social cultural factors can influence the three-stage KMS diffusion process, that is, initiation, adoption, and routinization. This study provides a holistic view of the KMS diffusion in Chinese enterprises with practical guidance for successful KMS implementation.

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Solli-Sæther, Hans, and Petter Gottschalk. "Maturity in Outsourcing Relationships." In Managing IT Outsourcing Performance, 98–117. IGI Global, 2010. http://dx.doi.org/10.4018/978-1-60566-796-6.ch005.

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Stages of growth models have been used widely in both organizational research and information technology management research. According to King and Teo (1997), these models describe a wide variety of phenomena – the organizational life cycle, product life cycle, biological growth, stages of growth in information systems, growth model for integration between business planning and information systems planning, electronic commerce evolution, stages of knowledge management technology, and a number of other interesting developments in time perspectives. These models assume that predictable patterns (conceptualized in terms of stages or levels) exist in the growth of organizations and organizational parts, the sales levels of products, and the growth of living organisms. These stages are (1) sequential in nature, (2) occur as a hierarchical progression that is not easily reversed, and (3) evolve a broad range of organizational activities and structures. This chapter starts with an introduction to stages of growth models. In the following sections we present the three-stage model for the evolution of IT outsourcing relationships (Gottschalk & Solli-Sæther, 2006). The three stages are labelled cost stage, resource stage, and partnership stage respectively. Theory-based benchmark variables for measuring maturity in IT outsourcing relationships are presented, followed by the stage hypothesis and a description of how benchmark variables are used to indicate characteristics at each stage of growth. Finally in this chapter, we present results from an exploratory study testing the stage model. The purpose of this chapter is to develop a framework for improved understanding of the current situation in an IT outsourcing relationship in terms of a specific stage, to develop strategies for moving to a higher stage in the future, and to learn from earlier stage experience.

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Merriam, Sharan B. "Qualitative Research." In Handbook of Research on Scholarly Publishing and Research Methods, 125–40. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-7409-7.ch007.

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This chapter takes the reader on a step-by-step journey through the process of conducting a qualitative research study using research conducted with Traditional Healers (THs) in Malaysia and how they diagnose and treat cancer. Upwards of 80% of Malaysians consult traditional healers before seeing a medical doctor, resulting in late-stage diagnoses and thus higher mortality rates. However, prior to our research, little was known about the role of healers and their willingness to work with, rather than outside, the Western medical system. Within this context, the theoretical framework, the specific research problem and the research questions were identified. Next, the author discusses purposive sampling and data collection strategies, which included interviews, documents, and observations. She then presents a data analysis exhibit showing how they captured specific data from the interviews to address the research questions. Finally, the author discusses writing and publishing the results of the research.

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Aligica, Paul Dragos, Peter J. Boettke, and Vlad Tarko. "Introduction." In Public Governance and the Classical-Liberal Perspective, 1–14. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190267032.003.0001.

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The introduction sets up the stage for the rest of the book by asking a series of key questions: Does classical liberalism entail a systematic framework of principles regarding public governance? If so, what are its broad recommendations and how does this perspective differ from other, more well-known perspectives on public administration? Classical liberalism accepts a wide range of collective arrangements and activities ranging from certain types of regulation to the provision of specific public goods and even to specific welfare policies. As such, the question arises, within the range of government activities accepted as legitimate, or at least not entirely beyond the pale, what are the particular classical-liberal views on the instruments and procedures of the administration of collective affairs? What kind of doctrine of governance and public administration does classical liberalism inspire? Is it possible to reconstruct or piece together such a position using the existing literature and practice?

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Streefkerk, Jan Willem, Myra P. van Esch-Bussemakers, Mark A. Neerincx, and Rosemarijn Looije. "Evaluating Context-Aware Mobile Interfaces for Professionals." In Handbook of Research on User Interface Design and Evaluation for Mobile Technology, 759–79. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-871-0.ch045.

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Evaluation refines and validates design solutions in order to establish adequate user experiences. For mobile user interfaces in dynamic and critical environments, user experiences can vary enormously, setting high requirements for evaluation. This chapter presents a framework for the selection, combination, and tuning of evaluation methods. It identifies seven evaluation constraints, that is, the development stage, the complexity of the design, the purpose, participants, setting, duration, and cost of evaluation, which influence the appropriateness of the method. Using a combination of methods in different settings (such as Wizard-of-Oz, game-based, and field evaluations) a concise, complete, and coherent set of user experience data can be gathered, such as performance, situation awareness, trust, and acceptance. Applying this framework to a case study on context-aware mobile interfaces for the police resulted in specific guidelines for selecting evaluation methods and succeeded to capture the mobile context and its relation to the user experience.

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Atti di convegni sul tema "Stage-specific framework"

Carmichael, Marc G., Richardo Khonasty, and Dikai Liu. "A multi-stage design framework for the development of task-specific robotic exoskeletons." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7318576.

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Ameta, Gaurav, Mahesh Mani, and He Huang. "A Design Framework for Bi-Level Estimation of Machining Energy for Parts and Assemblies." In ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/detc2009-86805.

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This paper presents a framework and approach for the computation of machining energy for parts and assemblies, at two levels — early design stage and manufacturing stage. Energy estimation at an early design stage can be useful for redesign strategies and improving manufacturing efficiency. At the manufacturing stage, energy estimations allow for asset management based on energy efficient process planning and scheduling, thereby reducing the negative impacts of the product to the environment. To facilitate the computation of the machining energy, at an early design stage, we first automate the

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Deng, Y. M., and W. F. Lu. "A Conceptual Design Synthesis Framework for Micro-Electro-Mechanical Systems (MEMS)." In ASME 2004 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/detc2004-57235.

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It is well recognized that conceptual design is the most critical stage of product development process. Yet, existing MEMS (Micro-Electro-Mechanical Systems) design synthesis models or methods are very restrictive in supporting MEMS conceptual design, in that they are only applicable to specific or specific types of designs, where building blocks for design synthesis have to be pre-specified by the designers. To address this problem, this paper proposes a MEMS conceptual design synthesis framework, which consists of a behavior representation that caters for the multidisciplinary MEMS design ch

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Hosangadi, Ashvin, Vineet Ahuja, and Ronald J. Ungewitter. "Generalized Numerical Framework for Cavitation in Inducers." In ASME/JSME 2003 4th Joint Fluids Summer Engineering Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/fedsm2003-45408.

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In this paper we present a capability to predict pump performance in cavitating flow regimes. Simulations of cavitating flowfields in a single-stage inducer type pump have been carried out. The pump used in this paper is the Simplex inducer geometry that has been extensively tested at NASA Marshall. We follow our turbomachinery simulations up with an extension of our cavitation model to cryogenic flow regimes, where temperature effects begin to play a significant role. Our framework encompasses an acoustically accurate, compressible multiphase model that has been previously validated. The mode

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Trachet, Bram, Marjolijn Renard, Gianluca De Santis, Steven Staelens, Julie De Backer, Luca Antiga, Bart Loeys, and Patrick Segers. "A Quantitative Comparison Between Baseline Hemodynamics and End-Stage Aneurysm Formation in ApoE −/− Mice." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53452.

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The pathogenesis of abdominal aortic aneurysm (AAA) formation still remains debated. Hemodynamics have been suggested to play a (modulating) role, but no follow-up studies have been performed due to (a.o.) a lack of human data before disease initiation. We therefore used an established mouse model of AAA [1] to study whether AAA develops at locations experiencing disturbed flow. We set up a framework to obtain mouse-specific Computational Fluid Dynamics (CFD) simulations of the mouse abdominal aorta, combining: (i) an in vivo assessed geometric model [2] and (ii) in vivo measured boundary cond

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Messer, Matthias, Ju¨rgen Grotepaß, Ulrich K. Frenzel, and Jitesh H. Panchal. "Towards a Function-Based Collective Innovation Framework." In ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/detc2009-86792.

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In this paper, we present a work-in-progress web-based framework to enable collective innovation via a combination of top-down structural and bottom-up self-organized processes in global enterprises. Problem: In current organizations, expertise is usually locked in discipline-specific project teams or departments based on existing product portfolios which restricts collective innovation through distributed networks of peers translating into increased innovation. Innovation projects are managed in stage gate processes using tools (such as proprietary project workspaces or product data managemen

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Iacob, Robert, Peter Mitrouchev, and Jean-Claude Le´on. "A Simulation Framework for Assembly/Disassembly Process Modeling." In ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/detc2007-34804.

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Simulations of Assembly/Disassembly (A/D) processes covers a large range of objectives, i.e. A/D sequencing, path finding, ergonomic analysis …, where the 3D shape description of the component plays a key role. In addition, the A/D simulations can be performed either from an automated or interactive point of view using standard computer equipment or through immersive and real-time simulation schemes. In order to address this diversity of configurations, this paper presents a simulation framework for A/D analysis based on a new simulation preparation process which allows a simulation process to

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Guan, Ziyu, Fei Xie, Wanqing Zhao, Xiaopeng Wang, Long Chen, Wei Zhao, and Jinye Peng. "Tag-based Weakly-supervised Hashing for Image Retrieval." In Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California: International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/525.

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We are concerned with using user-tagged images to learn proper hashing functions for image retrieval. The benefits are two-fold: (1) we could obtain abundant training data for deep hashing models; (2) tagging data possesses richer semantic information which could help better characterize similarity relationships between images. However, tagging data suffers from noises, vagueness and incompleteness. Different from previous unsupervised or supervised hashing learning, we propose a novel weakly-supervised deep hashing framework which consists of two stages: weakly-supervised pre-training and sup

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Lee, Jinwook, Choon S. Tan, Borislav T. Sirakov, Chris Wilkins, Hong-Sik Im, Martin Babak, and Denis Tisserant. "Performance Characterization of Twin Scroll Turbine Stage for Vehicular Turbocharger Under Unsteady Pulsating Flow Environment." In ASME Turbo Expo 2016: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/gt2016-56401.

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Unsteady three-dimensional computations have been implemented on a turbocharger twin-scroll turbine system (volute-turbine wheel-diffuser). The flow unsteadiness in a turbocharger turbine system is essentially driven by a highly pulsating flow from the upstream combustor which causes a pulsating stagnation pressure boundary condition at the inlet to the turbine system. Computed results have been post-processed and interrogated in depth in order to infer the significance of the induced flow unsteadiness on performance. The induced flow unsteadiness could be deemed important since the reduced fr

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Saha, Bidyut B., Ibrahim I. El-Sharkawy, Anutosh Chakraborty, Shigeru Koyama, and Kim Choon Ng. "Study on Single- and Multi-Stage Adsorption Cooling Cycles Working at Sub and Above Atmospheric Conditions." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68616.

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This study deals with the performance analysis of single- and multi-stage adsorption cooling cycles working at partial vacuum and pressurized conditions for cooling applications. Four adsorbent-refrigerant pairs namely activated carbon fiber-ethanol, silica gel-water, Maxsorb II-R134a and Fluka-R134a pairs have been investigated. The former two pairs are deemed to be suitable for adsorption cycles working at pressures ranging from 1 to 11 kPa while the latter two are suitable for those working at above atmospheric pressure conditions typically between about 0.3 and 0.8 MPa. Invoking the adsorp

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Rapporti di organizzazioni sul tema "Stage-specific framework"

Bagley, Margo. Genome Editing in Latin America: CRISPR Patent and Licensing Policy. Inter-American Development Bank, July 2021. http://dx.doi.org/10.18235/0003409.

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The power and promise of genome editing, CRISPR specifically, was first realized with the discovery of CRISPR loci in the 1980s.i Since that time, CRISPR-Cas systems have been further developed enabling genome editing in virtually all organisms across the tree of life.i In the last few years, we have seen the development of a diverse set of CRISPR-based technologies that has revolutionized genome manipulation.ii Enabling a more diverse set of actors than has been seen with other emerging technologies to redefine research and development for biotechnology products encompassing food, agriculture

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Kuiken, Todd, and Jennifer Kuzma. Genome Editing in Latin America: Regional Regulatory Overview. Inter-American Development Bank, July 2021. http://dx.doi.org/10.18235/0003410.

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Abstract (sommario):

The power and promise of genome editing, CRISPR specifically, was first realized with the discovery of CRISPR loci in the 1980s.3 Since that time, CRISPR-Cas systems have been further developed enabling genome editing in virtually all organisms across the tree of life.3 In the last few years, we have seen the development of a diverse set of CRISPR-based technologies that has revolutionized genome manipulation.4 Enabling a more diverse set of actors than has been seen with other emerging technologies to redefine research and development for biotechnology products encompassing food, agriculture,

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