Letteratura scientifica selezionata sul tema "Suturectomy"
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Articoli di riviste sul tema "Suturectomy"
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Frazier, Brenda C., Mark P. Mooney, H. Wolfgang Losken, Tim Barbano, Amr Moursi, Michael I. Siegel e Joan T. Richtsmeier. "Comparison of Craniofacial Phenotype in Craniosynostotic Rabbits Treated with Anti–Tgf-β2 at Suturectomy Site". Cleft Palate-Craniofacial Journal 45, n. 6 (novembre 2008): 571–82. http://dx.doi.org/10.1597/07-095.1.
Testo completoAbstract (sommario):
Objective: Overexpression of transforming growth factor-beta 2 has been associated with craniosynostosis and resynostosis following surgery. We examined the effects of localized transforming growth factor-beta 2 inhibition on craniofacial phenotype in rabbits with craniosynostosis. Design: Twenty-five New Zealand white rabbits with bilateral coronal craniosynostosis were divided into three treatment groups: (1) suturectomy control (n = 8); (2) suturectomy with nonspecific, control immunoglobulin G antibody (n = 6); and (3) suturectomy with anti–transforming growth factor-beta 2 antibody (n = 11). At 10 days of age, a coronal suturectomy was performed on all rabbits. The sites in groups 2 and 3 were immediately filled with a slow-resorbing collagen gel mixed with either immunoglobulin G or anti–transforming growth factor-beta 2 antibody. Computed tomography scans of each rabbit were acquired at ages 10, 25, and 84 days. Craniofacial landmarks were collected from three-dimensional computed tomography reconstructions, and growth and form were compared among the three groups. Results: Rabbits treated with anti–transforming growth factor-beta 2 antibody differed in form at 84 days of age compared with suturectomy control rabbits, specifically in the snout and posterior neurocranium. Growth in some areas of the skull was greater in rabbits from the anti–transforming growth factor-beta 2 group than in suturectomy control rabbits, but not significantly greater than in IgG control rabbits. Conclusions: We find support for the hypothesis that transforming growth factor-beta 2 inhibition alters adult form, but these changes do not appear to be localized to the suturectomy region. Slight differences in form and growth between the two control groups suggest that the presence of the collagen vehicle itself may affect skull growth.
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Sood, Sandeep, Arlene Rozzelle, Blerina Shaqiri, Natasha Sood e Steven D. Ham. "Effect of molding helmet on head shape in nonsurgically treated sagittal craniosynostosis". Journal of Neurosurgery: Pediatrics 7, n. 6 (giugno 2011): 627–32. http://dx.doi.org/10.3171/2011.4.peds116.
Testo completoAbstract (sommario):
Object Sagittal craniosynostosis is traditionally considered to be a surgical condition. Poor results of simple suturectomy follow from early reclosure of the suture. A wider craniectomy or use of interposing materials has not improved the outcome. However, endoscopic suturectomy supplemented with postoperative use of a molding helmet has shown good results. Because suturectomy reunites within 8–12 weeks of surgery, the authors questioned if the improved outcome was primarily related to use of the helmet. Methods In 4 patients whose families opted for calvarial reconstruction when the infant was 4–6 months old, instead of endoscopic suturectomy, a molding helmet was used to minimize compensatory changes in the interim. Patients underwent 3D CT scanning to confirm craniosynostosis. Follow-up visits were made at intervals of 4 weeks for adjustment of the helmet, head circumference measurements, clinical photographs, and cranial index measurement. Results There was significant improvement in the head shape within 6 weeks of use of the molding helmet. The cranial index score improved from a mean (± SD) of 67% ± 3% to 75% ± 2%. Conclusions These cases demonstrate that molding helmets improve head shape even without a suturectomy in patients with sagittal craniosynostosis, challenging the traditional view.
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Mooney, Mark P., Annie M. Burrows, Timothy D. Smith, H. Wolfgang Losken, Lynne A. Opperman, Jason Dechant, Amy M. Kreithen et al. "Correction of Coronal Suture Synostosis Using Suture and Dura Mater Allografts in Rabbits with Familial Craniosynostosis". Cleft Palate-Craniofacial Journal 38, n. 3 (maggio 2001): 206–25. http://dx.doi.org/10.1597/1545-1569_2001_038_0206_cocssu_2.0.co_2.
Testo completoAbstract (sommario):
Objective: Resynostosis following surgical correction of craniosynostosis is a common clinical correlate. Recent studies suggest that the dura mater is necessary to maintain suture patency. It has also been hypothesized that dura mater from synostotic individuals may provide aberrant biochemical signals to the osteogenic fronts of the calvaria, which result in premature suture fusion and subsequent resynostosis following surgery. This study was designed to test this hypothesis by surgically manipulating the coronal suture and dura mater in rabbits with familial craniosynostosis to prevent postsurgical resynostosis. Design: Craniofacial growth and histomorphometric data were collected from 129 rabbits: 72 normal controls and 57 rabbits with bilateral coronal suture synostosis (15 unoperated on controls; 13 surgical controls; 9 dura mater transplant only; 10 suture transplant only; and 10 suture and dura mater transplant). At 10 days of age, all rabbits had radiopaque amalgam markers placed on either side of the coronal, frontonasal, and anterior lambdoidal sutures. At 25 days of age, 42 synostosed rabbits had a 3 to 5-mm wide coronal suturectomy. Coronal sutures and/or underlying dura mater allografts were harvested from same-aged, wild-type, isohistogenic control rabbits and transplanted onto the dura mater of synostosed host rabbits. Serial radiographs were taken at 10, 25, 42, and 84 days of age, and the suturectomy sites were harvested at 84 days of age in 44 rabbits and serially sectioned for histomorphometric examination. Results: Results revealed that cranial vault growth was significantly (p < .05) improved following surgical release of the fused coronal suture compared with synostosed rabbits who were not operated on but was still significantly different (p < .05) from that of normal control rabbits. By 84 days of age, significant (p < .05) differences were noted in calvarial suture marker separation, cranial vault shape indices, and cranial base angles between rabbits with and without dura mater allografts, probably as a result of resynostosis of the suturectomy site or suture-only allografts. Qualitative histological examination revealed that at 84 days of age rabbits with suture and dura allografts had patent coronal sutures, suture-only allografts had fused coronal sutures with extensive endosteal hyperostosis, dura mater–only allografts had some new bone in the suturectomy site that resembled rudimentary osteogenic fronts, and suturectomy controls had extensive endosteal bone formation and resynostosis of the suturectomy site. Significantly (p < .05) more bone was found in the suturectomy sites of rabbits without dura mater allografts compared with rabbits with dura mater allografts. Conclusions: Results support the initial hypothesis that normal dura mater allografts will maintain suture or suturectomy site patency and allow unrestricted craniofacial growth. However, it is still unclear whether the dura mater from normal rabbits was providing biochemical signals to the transplanted sutures or suturectomy sites or simply acting as a barrier to prevent abnormal biochemical signals from the dura mater of synostosed rabbits from reaching the calvaria. The clinical and therapeutic implications of these procedures are discussed.
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McDowell, Michael M., Robert Kellogg, Jesse A. Goldstein e Taylor J. Abel. "Endoscope-assisted right coronal suturectomy". Neurosurgical Focus: Video 4, n. 2 (aprile 2021): V11. http://dx.doi.org/10.3171/2021.1.focvid20130.
Testo completoAbstract (sommario):
Endoscopic suturectomy combined with supplementary techniques such as spring-assisted expansion and cranial molding helmets for the correction of craniosynostosis is growing in popularity due to the reduced scar burdened, decreased morbidity, and reduced overall cost. The authors present their technique for the correction of isolated coronal craniosynostosis. The use of dedicated endoscopic tools and lit endoscopes permits enhanced visualization and technical ability, particularly at the distal portions of the suturectomy, and may reduce operative time and cerebrospinal fluid leak risk. The video can be found here: https://vimeo.com/515401366.
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Tombeng, Marthinson Andrew, e I. Wayan Niryana. "Open suturectomy management in craniosynostosis of bilateral coronal and metopic suture". Neurologico Spinale Medico Chirurgico 4, n. 1 (31 marzo 2021): 15–18. http://dx.doi.org/10.36444/nsmc.v4i1.145.
Testo completoAbstract (sommario):
Craniosynostosis is a cranial deformation that is characterized by the premature fusion of one or more of the cranial sutures. Synostosis of multiple suture is a rare case and can be treated with open suturectomy procedure which is one of the surgical management by removing the fused suture with the purpose to allow the constricted area to expand with the growing brain. We present a case of a 2-month-old male infant with abnormal head shape since birth with a non-contrast 3D computed tomography (CT) scan of the head confirmed closure of the bilateral coronal and metopic suture. Open suturectomy was performed with no post operative complications. Open suturectomy technique can be performed in the management of multisutural craniosynostosis as indicated. The diagnosis of which suture are affected, the timing of surgery, and the prevention of surgical complication such as excessive blood loss are the important factors need to be considered.
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Ridgway, Emily B., John Berry-Candelario, Ronald T. Grondin, Gary F. Rogers e Mark R. Proctor. "The management of sagittal synostosis using endoscopic suturectomy and postoperative helmet therapy". Journal of Neurosurgery: Pediatrics 7, n. 6 (giugno 2011): 620–26. http://dx.doi.org/10.3171/2011.3.peds10418.
Testo completoAbstract (sommario):
Object Suturectomy as a treatment for craniosynostosis was largely replaced in the late twentieth century by more extensive, but predictable, cranial remodeling procedures. Recent technical innovations, such as using the endoscope combined with postoperative orthotic reshaping, have led to a resurgence of interest in suturectomy as a safer, less invasive method. Methods A retrospective chart review was performed for all cases of sagittal synostosis treated with endoscopic sagittal suture strip craniectomy and helmet therapy between 2004 and 2008. Data collected included gestational age, genetic evaluations and syndromic status, age at operation, duration of procedure, need for blood transfusions, length of hospital stay, preoperative and postoperative head circumference percentile and cranial index, duration of helmet use, length of follow-up, complications, and revisions. Results Fifty-six patients with isolated sagittal synostosis were treated using endoscopic suturectomy and completed helmet therapy. Mean age at time of procedure was 3.24 months. Mean operative duration was 45.32 minutes. Mean hospital stay was 1.39 days. There were 2 transfusions and no deaths. The mean length of follow-up was 2.34 years. Helmet therapy was instituted for a mean of 7.47 months. Head circumference percentile increased from 61.42% to 89.27% over 2 years of follow-up. Cranial index increased from a preoperative mean of 0.69 to 0.76 over 2 years of follow-up. Reoperations for synostosis included 1 sagittal suture refusion and 2 cases in which other sutures fused. Conclusions Sagittal synostosis can be safely treated with endoscopic suturectomy and helmet therapy. Improvements in cranial volume and shape are comparable to open procedures and are enduring.
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McGahan, Ben G., Joravar Dhaliwal, Gregory D. Pearson, Ibrahim Khansa e Annie I. Drapeau. "A Case Series of the Use of Piezosurgery Instrument for Minimally Invasive Metopic Suturectomy". Operative Neurosurgery 20, n. 6 (6 febbraio 2021): 529–34. http://dx.doi.org/10.1093/ons/opab006.
Testo completoAbstract (sommario):
Abstract BACKGROUND Minimal invasive suturectomy is one of the many surgical approaches to treat isolated single suture craniosynostosis. This approach can be technically challenging in metopic craniosynostosis given the narrow corridor and steep angle of the forehead. New instruments such as the Piezosurgery device (Mectron) have the potential to improve the ability to safely perform minimal invasive surgery in metopic craniosynostosis. OBJECTIVE To demonstrate the safety and efficacy of Piezosurgery technology in minimal invasive suturectomy for nonsyndromic metopic suture craniosynostosis and to describe our technique. METHODS A retrospective chart review was performed of all the single metopic suturectomies performed at our single institution from March 2018 to November 2019. Pre-, intra-, and postoperative data were collected to assess the safety of Piezosurgery. RESULTS The cohort consisted of 12 patients with an average of 95.25 d old and an average weight of 6.2 kg. A total of 91.7% were male, and 91.7% were Caucasian. There were no intraoperative or postoperative Piezosurgery device-related complications in the entire cohort. CONCLUSION The use of the Piezosurgery instrument was safe in this cohort of minimal invasive metopic suturectomy. This device has greatly increased the ease of this procedure in our hands.
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Dlouhy, Brian J., Dennis C. Nguyen, Kamlesh B. Patel, Gwendolyn M. Hoben, Gary B. Skolnick, Sybill D. Naidoo, Albert S. Woo e Matthew D. Smyth. "Endoscope-assisted management of sagittal synostosis: wide vertex suturectomy and barrel stave osteotomies versus narrow vertex suturectomy". Journal of Neurosurgery: Pediatrics 18, n. 6 (dicembre 2016): 674–78. http://dx.doi.org/10.3171/2016.6.peds1623.
Testo completoAbstract (sommario):
OBJECTIVE Endoscope-assisted methods for treatment of craniosynostosis have reported benefits over open calvarial vault reconstruction. In this paper, the authors evaluated 2 methods for endoscope-assisted correction of sagittal synostosis: wide vertex suturectomy and barrel stave osteotomies (WVS+BSO) and narrow vertex suturectomy (NVS). METHODS The authors evaluated patients with nonsyndromic sagittal synostosis treated with either wide vertex suturectomy (4–6 cm) and barrel stave osteotomies (WVS+BSO) or narrow vertex suturectomy (NVS) (approximately 2 cm) between October 2006 and July 2013. Prospectively collected data included patient age, sex, operative time, estimated blood loss (EBL), postoperative hemoglobin level, number of transfusions, complications, and cephalic index. Fourteen patients in the NVS group were age matched to 14 patients in the WVS+BSO group. Descriptive statistics were calculated, and Student t-tests were used to compare prospectively obtained data from the WVS+BSO group with the NVS group in a series of univariate analyses. RESULTS The mean age at surgery was 3.9 months for WVS+BSO and 3.8 months for NVS. The mean operative time for patients undergoing NVS was 59.0 minutes, significantly less than the 83.4-minute operative time for patients undergoing WVS+BSO (p < 0.05). The differences in mean EBL (NVS: 25.4 ml; WVS+BSO: 27.5 ml), mean postoperative hemoglobin level (NVS: 8.6 g/dl; WVS+BSO: 8.0 g/dl), mean preoperative cephalic index (NVS: 69.9; WVS+BSO: 68.2), and mean cephalic index at 1 year of age (NVS: 78.1; WVS+BSO: 77.2) were not statistically significant. CONCLUSIONS The NVS and WVS+BSO produced nearly identical clinical results, as cephalic index at 1 year of age was similar between the 2 approaches. However, the NVS required fewer procedural steps and significantly less operative time than the WVS+BSO. The NVS group obtained the final cephalic index in a similar amount of time postoperatively as the WVS+BSO group. Complications, transfusion rates, and EBL were not different between the 2 techniques.
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Kyutoku, Shigeo, Masahiro Iwanaga, Toyoko Okamoto, Atsuko Harada e Koichi Ueda. "Wider Suturectomy Before Posterior Distraction for Craniosynostosis". Journal of Craniofacial Surgery 30, n. 1 (2019): 71–73. http://dx.doi.org/10.1097/scs.0000000000004911.
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Harada, Atsuko, Shigeo Kyutoku, Yuki Kimoto, Reina Utsugi, Takahiro Fujinaga, Hideyuki Arita, Kazushige Maeno e Koichi Ueda. "Preliminary Report on Endoscopy-assisted Suturectomy for Craniosynostosis". Japanese Journal of Neurosurgery 29, n. 7 (2020): 498–505. http://dx.doi.org/10.7887/jcns.29.498.
Testo completoTesi sul tema "Suturectomy"
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Thwin, May. "Comparative outcomes of craniectomy versus cranial remodelling in the human infant with isolated sagittal synostosis". Thesis, 2015. http://hdl.handle.net/2440/92541.
Testo completoAbstract (sommario):
BACKGROUND Craniosynostosis is a congenital condition characterised by the premature closure of one or more cranial sutures. The sagittal suture is the most common site, comprising 40-60% of cases. Premature fusion of this suture can cause scaphocephaly, seen morphologically as a narrow elongated skull with a decreased cephalic index. Diagnosis is made clinically and/or radiologically. The goals of surgical correction and the techniques used have evolved over time. Whilst there has been a general move from limited craniectomy to calvarial remodelling, in recent times there has been a return towards less invasive methods. OBJECTIVES The objectives were to identify and synthesize the best available evidence on the morphological, functional and neurological outcomes of craniectomy compared to cranial vault remodelling and compare this to existing results. METHODS A systematic review of the literature was conducted using the Joanna Briggs Institute methodology. The review considered studies of infants with primary isolated sagittal synostosis operated on before a mean of two years of age. The intervention of interest was sagittal craniectomy; this was compared to cranial vault remodelling. Morphological, functional and neurological outcomes were included. Mortality, complications and aesthetic outcome were included as tertiary outcomes. A comprehensive search was undertaken across major databases. Retrieved studies were assessed by two independent reviewers for methodological validity. Data was extracted and where possible, pooled in statistical meta-analysis. Where this was not possible, findings were presented in narrative form. RESULTS Based on critical appraisal 27 studies, all descriptive in nature, were of suitable quality for inclusion. Meta-analysis was only possible for the primary morphological outcome (mean change in cephalic index post-operatively) based on two studies. This showed that at one year post-operative follow-up remodelling offers an advantage over craniectomy (Z = 4.16, P<0.0001). Narrative synthesis suggests that improvements of cephalic index to varying degrees were seen in patients receiving either procedure; whilst the mean change appears to peak early in patients who have undergone remodelling procedures, the trend suggests it may improve in the longer term after craniectomy. Whilst global IQ scores may be comparable to an age-matched population, narrative review suggests that patients with sagittal synostosis who have undergone a surgical correction of any type may have discrepancies in specific domains and may be at risk of developing learning disorders. There is insufficient primary research with inter-procedure comparison of pre-operative and post-operative cognitive or neurological outcome. CONCLUSIONS At one year follow-up, remodelling is superior to craniectomy in terms of mean change in cephalic index. However both procedures were seen to give improvements in the short, medium and long term. Neither procedure offers a distinct sustained advantage; longer follow-up is required to assess the comparative improvement over time. There is insufficient evidence whether craniectomy or remodelling procedures offer superior functional or neurological outcome. Patients who have had surgical repair (any type) may have deficiencies in different subdomains and be at risk of learning disorders, whilst maintaining an age-appropriate global IQ and school performance. It is unknown if either surgery impart any restorative or protective benefit.Thesis (M.Clin.Sc.) -- University of Adelaide, School of Translational Health Science, 2015
Capitoli di libri sul tema "Suturectomy"
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Caycedo, Diego José, Marcela Cabal Castro e Luís Fernando Santacruz. "Telescoping with Multiple Revolution Cranial Osteotomies in Patients with Simple Craniosynostosis". In Spina Bifida - New Perspectives and Clinical Applications [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94926.
Testo completoAbstract (sommario):
Simple craniosynostosis is a cranial deformity that occurs secondary to a premature closure of one or more sutures, with a consequent alteration in cranial growth and cerebral expansion. The cranial alteration presents as flattening parallel to the compromised suture, with compensatory bulging in a perpendicular vector. The surgical treatment consists in cranial decompressions with suturectomies and simultaneous cranioplasties. Dynamic multiple revolution osteotomies allow the design of bone flaps that can help with decompression and correct secondary deformities caused by the synostosis. This multicenter descriptive case series study assessed 52 patients (12 plagiocephaly, 29 scaphocephaly, 7 brachycephaly and 4 trigonocephaly) operated in Cali, Colombia. In each case, suturectomy and telescoping with multiple revolution cranial osteotomies were designed to correct each particular deformity. No clinical complications were observed in the postoperative period (1, 90, and 180 days), and excellent outcomes with no re ossification of sutures and maintenance of the cranioplasty, based on clinical observation and findings in the 3D reconstruction scans.
Atti di convegni sul tema "Suturectomy"
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Silva, Dulanka, Jonathan Halim, Curtis Budden, David Dunaway, Owase Jeelani, Juling ONg e Greg James. "116 Initial UK series of endoscopic suturectomy with post-operative helmet therapy for craniosynostosis: early report of peri-operative experience". In GOSH Conference 2020 – Our People, Our Patients, Our Hospital. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2020. http://dx.doi.org/10.1136/archdischild-2020-gosh.116.
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