Letteratura scientifica selezionata sul tema "T cell"

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Articoli di riviste sul tema "T cell"

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Ohshima, Kôichi, Junji Suzumiya, and Masahiro Kikuchi. "T cell rich B cell lymphoma." Journal of the Japan Society of the Reticuloendothelial System 36, no. 5-6 (1996): 391–93. http://dx.doi.org/10.3960/jslrt1961.36.391.

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Y, Elshimali. "Chimeric Antigen Receptor T-Cell Therapy (Car T-Cells) in Solid Tumors, Resistance and Success." Bioequivalence & Bioavailability International Journal 6, no. 1 (2022): 1–6. http://dx.doi.org/10.23880/beba-16000163.

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CARs are chimeric synthetic antigen receptors that can be introduced into an immune cell to retarget its cytotoxicity toward a specific tumor antigen. CAR T-cells immunotherapy demonstrated significant success in the management of hematologic malignancies. Nevertheless, limited studies are present regarding its efficacy in solid and refractory tumors. It is well known that the major concerns regarding this technique include the risk of relapse and the resistance of tumor cells, in addition to high expenses and limited affordability. Several factors play a crucial role in improving the efficacy
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CPK, Cheung. "T Cells, Endothelial Cell, Metabolism; A Therapeutic Target in Chronic Inflammation." Open Access Journal of Microbiology & Biotechnology 5, no. 2 (2020): 1–6. http://dx.doi.org/10.23880/oajmb-16000163.

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The role of metabolic reprogramming in the coordination of the immune response has gained increasing consideration in recent years. Indeed, it has become clear that changes in the metabolic status of immune cells can alter their functional properties. During inflammation, stimulated immune cells need to generate sufficient energy and biomolecules to support growth, proliferation and effector functions, including migration, cytotoxicity and production of cytokines. Thus, immune cells switch from oxidative phosphorylation to aerobic glycolysis, increasing their glucose uptake. A similar metaboli
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Rimpo, Kenji, Yumiko Kagawa, and Tetsushi Yamagami. "T-cell-rich B-cell lymphoma in a dog." Journal of Japan Veterinary Cancer Society 4, no. 1 (2013): 1–5. http://dx.doi.org/10.12951/jvcs.2012-001.

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Toner, Keri, Catherine M. Bollard, and Hema Dave. "T-cell therapies for T-cell lymphoma." Cytotherapy 21, no. 9 (2019): 935–42. http://dx.doi.org/10.1016/j.jcyt.2019.04.058.

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Fitch, F. W. "T-cell clones and T-cell receptors." Microbiological Reviews 50, no. 1 (1986): 50–69. http://dx.doi.org/10.1128/mmbr.50.1.50-69.1986.

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Fitch, F. W. "T-cell clones and T-cell receptors." Microbiological Reviews 50, no. 1 (1986): 50–69. http://dx.doi.org/10.1128/mr.50.1.50-69.1986.

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Mohapatra, Manisha, and Yerraguntala Subramanya Sarma. "T-Cell/ Histiocyte-Rich Large B-Cell Lymphoma of Posterior Mediastinum." Annals of Pathology and Laboratory Medicine 6, no. 6 (2019): C63–66. http://dx.doi.org/10.21276/apalm.2389.

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Chinnikatti, Shravana kumar, Soumya shravan, H. N. Asikur Rahaman, and Shraavya Shraavya. "New Treatments for Synovial Cell Sarcoma with Genetically Modified T-Cell?" Cancer Research and Cellular Therapeutics 6, no. 3 (2022): 01–02. http://dx.doi.org/10.31579/2640-1053/113.

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Synovial cell sarcoma is rare but very aggressive tumour if not treated early, due to the painless nature of this tumour patients normally come in late and advances stage, can occur in bones, muscle cells, cartilages, ligaments and de-novo from pleuripotent stem cells from asnywhere in the body but most commonly arm, leg, or foot, and near joints such as the wrist or ankle and possibly from any joints in the body, even from soft tissues of lung and abdomen, the other name for this tumour is called malignant synovioma.The 5 year survival after the effective primary treatment is 30-75% and the s
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Udhayakumar, Venkatachalam, Bondada Subbarao, Aruna Seth, Mitzi Nagarkatti, and Prakash S. Nagarkatti. "Impaired autoreactive T cell-induced T cell-T cell interaction in aged mice." Cellular Immunology 116, no. 2 (1988): 299–307. http://dx.doi.org/10.1016/0008-8749(88)90232-8.

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Tesi sul tema "T cell"

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Sarris, Milka. "Dynamics of helper T cell and regulatory T cell interactions with dendritic cells." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611896.

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Carson, Bryan David. "Impaired T cell receptor signaling in regulatory T cells /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8337.

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Lloyd, Angharad. "Gene editing in T-cells and T-cell targets." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/98512/.

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Recent years have witnessed a rapid proliferation of gene editing in mammalian cells due to the increasing ease and reduced cost of targeted gene knockout. There has been much excitement about the prospect of engineering T-cells by gene editing in order to provide these cells with optimal attributes prior to adoptive cell therapy for cancer and autoimmune disease. I began by attempting to compare short hairpin RNA (shRNA) and zinc finger nuclease (ZFN) approaches using the CD8A gene as a target for proof of concept of gene editing in Molt3 cells. During the course of my studies the clustered r
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Stefkova, Martina. "Regulatory T cells control the CD4 T cell repertoire." Doctoral thesis, Universite Libre de Bruxelles, 2016. https://dipot.ulb.ac.be/dspace/bitstream/2013/233151/3/Table.pdf.

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Des études récentes menées chez l’homme et la souris ont suggéré que la diversité du répertoire TCR pourrait jouer un rôle dans la protection contre des pathogènes à haut pouvoir mutagène. Afin d’étudier le répertoire des lymphocytes T CD4, nous avons utilisé un modèle de souris TCRβ transgéniques exprimant une chaine β spécifique du peptide env122-141 dans le contexte du MHCII. Suite à l’immunisation des souris TCRβ transgéniques avec des cellules dendritiques pulsées avec le peptide env, une rapide prolifération et une restriction du répertoire des lymphocytes T Vα2 CD4 spécifiques est obser
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Smith, Trevor Robert Frank. "Modulation of CD4+ T cell responses by CD4+CD25+ regulatory T cells and modified T cell epitopes." Thesis, Imperial College London, 2004. http://hdl.handle.net/10044/1/11317.

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Sommermeyer, Daniel. "Generation of dual T cell receptor (TCR) T cells by TCR gene transfer for adoptive T cell therapy." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2010. http://dx.doi.org/10.18452/16051.

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Die Herstellung von T-Zellen mit definierten Spezifitäten durch den Transfer von T-Zellrezeptor (TCR) Genen ist eine effiziente Methode, um Zellen für eine Immuntherapie bereitzustellen. Eine besondere Herausforderung ist dabei, ein ausreichend hohes Expressionsniveau des therapeutischen TCR zu erreichen. Da T-Zellen mit einem zusätzlichen TCR ausgestattet werden, entsteht eine Konkurrenzsituation zwischen dem therapeutischen und dem endogenen TCR. Bevor diese Arbeit begonnen wurde war nicht bekannt, welche TCR nach einem Gen-Transfer exprimiert werden. Daher haben wir Modelle etabliert, in de
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Tyznik, Aaron Jacob. "CD4+ T cell help for CD8+ T cell responses /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8314.

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Butcher, Sarah A. "T cell receptor genes of influenza A haemagglutinin specific T cells." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315271.

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Raeiszadeh, Mohammad. "Reconstitution of CMV-specific T-cells following adoptive T-cell immunotherapy and haematopoietic stem cell transplantation." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6968/.

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This thesis investigated reconstitution of CMV-specific T-cells in two cohorts of HSCT patients and studied the potential role of Tumour Necrosis Factor Receptor 2 (TNFR2) in regulation of CMV-specific T-cell expansion post HSCT. The first cohort included patients of a randomized phase II trial of adoptive cellular therapy for CMV-specific CD8\(^+\) T-cells. Cellular therapy resulted in earlier and greater expansion of CMV-specific CD8\(^+\) T cells and also reconstitution of CMV-specific CD4\(^+\) and non-infused CMV-specific CD8\(^+\) T-cells. The number of infused therapeutic T-cells and ci
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Kanazawa, Nobuo. "Fractalkine and macrophage-derived chemokine : T cell attracting chemokines expressed in T cell area dendritic cells." Kyoto University, 2000. http://hdl.handle.net/2433/180886.

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Libri sul tema "T cell"

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1956-, Zhang Jingwu, and Cohen Irun R, eds. T-cell vaccination. Nova Biomedical Books, 2008.

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Kearse, Kelly P. T Cell Protocols. Humana Press, 1999. http://dx.doi.org/10.1385/1592596827.

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Lugli, Enrico, ed. T-Cell Differentiation. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6548-9.

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Rainger, George Edward, and Helen M. Mcgettrick, eds. T-Cell Trafficking. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6931-9.

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Foss, Francine, ed. T-Cell Lymphomas. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-170-7.

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Verma, Navin Kumar, ed. T-Cell Motility. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9036-8.

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Libero, Gennaro, ed. T Cell Protocols. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-527-9.

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Marelli-Berg, Federica M., and Sussan Nourshargh, eds. T-Cell Trafficking. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-461-6.

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Bosselut, Rémy, and Melanie S. Vacchio, eds. T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5.

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Bosselut, Remy, and Melanie S. Vacchio, eds. T-Cell Development. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2740-2.

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Capitoli di libri sul tema "T cell"

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Gooch, Jan W. "T Cell." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14928.

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Bland, P. W. "Mucosal T Cell-Epithelial Cell Interactions." In Mucosal T Cells. KARGER, 1998. http://dx.doi.org/10.1159/000058714.

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Simmons, Amie, and José Alberola-Ila. "Retroviral Transduction of T Cells and T Cell Precursors." In T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5_8.

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Chen, C. H., A. Six, T. Kubota, et al. "T Cell Receptors and T Cell Development." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80057-3_5.

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Yamaguchi, Motoko, and Kensei Tobinai. "NK-Cell Neoplasms." In T-Cell Lymphomas. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-170-7_6.

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Sarris, Milka, and Alexander G. Betz. "Live Imaging of Dendritic Cell–Treg Cell Interactions." In Regulatory T Cells. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61737-979-6_7.

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Vacchio, Melanie S., Thomas Ciucci, and Rémy Bosselut. "200 Million Thymocytes and I: A Beginner’s Survival Guide to T Cell Development." In T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5_1.

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Wohlfert, Elizabeth A., Andrea C. Carpenter, Yasmine Belkaid, and Rémy Bosselut. "In Vitro Analyses of T Cell Effector Differentiation." In T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5_10.

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Ross, Jenny O., Heather J. Melichar, Joanna Halkias, and Ellen A. Robey. "Studying T Cell Development in Thymic Slices." In T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5_11.

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Cunningham, Cody A., Emma Teixeiro, and Mark A. Daniels. "FTOC-Based Analysis of Negative Selection." In T-Cell Development. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2809-5_12.

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Atti di convegni sul tema "T cell"

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Mamonkin, Maksim. "Abstract IA17: CAR T cells for T-cell lymphoma." In Abstracts: AACR Virtual Meeting: Advances in Malignant Lymphoma; August 17-19, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2643-3249.lymphoma20-ia17.

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van der Stegen, Sjoukje J. C., Maria Themeli, Justin Eyquem, Jorge Mansilla-Soto, and Michel Sadelain. "Abstract 2309: T-cell development from T cell-derived induced pluripotent stem cell." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2309.

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Duan, Zhipu, Zhuohui Lin, and Shijie Zhou. "Universal CAR T cell: engineering of universal T cell, modular CAR system, and applications." In 2021 International Conference on Medical Imaging, Sanitation and Biological Pharmacy. Clausius Scientific Press, 2021. http://dx.doi.org/10.23977/misbp.2021036.

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Universal Chimeric Antigen Receptor T cells (CAR T), an alternative design based on conventional CAR T cells, uses a switchable adaptor for a better redirection towards the target site. This technology overcomes the obstacles of the conventional Car T cells system, such as immunogenicity, massive expression of cytokine and fixed antigen specificity. This article introduces universal CAR T cells from both the perspectives of the universal T cells and its modular CAR systems, illustrating the advancement of universal CAR T cells to overcome the limitation of conventional CAR T cells and serve as
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Jakobsen, Bent. "Abstract 2802: Fine-tuning T cell receptors for adoptive T cell therapy." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2802.

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Wilking, Alice, Lili Wang, Benjamin K. Chen, Thomas Huser, and Wolfgang Hubner. "Resolving T cell — T cell transfer of HIV-1 by optical nanoscopy." In 2017 Conference on Lasers and Electro-Optics Europe (CLEO/Europe) & European Quantum Electronics Conference (EQEC). IEEE, 2017. http://dx.doi.org/10.1109/cleoe-eqec.2017.8087773.

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Kristensen, Nikolaj Pagh, Christina Heeke, Siri A. Tvingsholm, et al. "Abstract A14: Neoepitope-specific CD8+ T cells in adoptive T-cell transfer." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a14.

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Chen, Gregory M., Changya Chen, Rajat K. Das, et al. "Abstract 4236: A subtype-specific T-cell transcriptomic atlas reveals determinants of T-cell dysfunction in CAR T-cell therapy resistance." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-4236.

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Ho, Chen-Ta, and Cheng-Hsien Liu. "Micro T-Switches for Cell Sorting Applications." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-61427.

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A new micro-T-switch actuated by electrochemical bubbles for cells sorting has been proposed and successfully demonstrated by MEMS micromachining technique. We take advantage of electrolysis-bubbles, which have the features of low operation temperature and high surface-tension force, to actuate the micro T- switches in our device. The micro-T-switch is placed at the junction of the T-shapes microchannel. The movable T-structure design makes cell sorting active and programmable compared with other passive cell sorting mechanism such as micro-filters. Furthermore, the low operation temperature f
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Eun, So-Young. "Abstract 1645: CEACAM1-blockade for T-cell activation and antitumor T-cell response." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1645.

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Takahashi, Hideyuki, Paulina Pathria, Ryan Shepard, Ann Shih, Tiani L. Louis та Judith A. Varner. "Abstract A86: PI3Kγ inhibition activates T cell memory and relieves T cell exhaustion". У Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 27-30, 2018; Miami Beach, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm18-a86.

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Rapporti di organizzazioni sul tema "T cell"

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HLADEK, K. L. T Plant Cell Investigation. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/807319.

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Bonnett, Megan. CAR T Cell Therapy. Iowa State University, 2019. http://dx.doi.org/10.31274/cc-20240624-337.

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Yompakdee, Chulee, and Sittiruk Roytrakul. Molecular target of an anti-cancer compound from leaves of Clausena harmandiana (Pierre). Chulalongkorn University, 2016. https://doi.org/10.58837/chula.res.2016.32.

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Clausena harmandiana (Pierre) Guillaumin or Song faa dong (in Thai), is classified in Family Rutaceae. Previous study, a coumarin compound designated CHA-01 was isolated from leave extract of C. harmandiana with inhibitory activity against calcium signaling in a ZDS1 null mutant yeast Saccharomyces cerevisiae (delta zds1). However, not much has been known on biological activity of this coumarin. In the past, some other coumarins were reported to contain anti-cancer activity. The aim of this research was to study molecular mechanism on antiproliferation activity of CHA-01 in Jurkat T cells. The
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Dotti, Gianpietro. Improve T Cell Therapy in Neuroblastoma. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada610046.

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Dotti, Gianpietro. Improve T Cell Therapy in Neuroblastoma. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada612327.

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Dotti, Gianpietro. Improve T Cell Therapy in Neuroblastoma. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada594698.

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Dotti, Gianpietro. Improve T Cell Therapy in Neuroblastoma. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada550874.

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Medof, M. E. Augmentation of Antitumor T-Cell Responses by Increasing APC T-Cell C5a/C3a-C5aR/C3aR Interactions. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada585489.

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หังสสูต, ปกรัฐ, та ญาดา ตันสิริ. การวิเคราะห์การยับยั้งการเพิ่มจำนวนของไวรัสเอชไอวีโดยทีเซลล์ : การทดสอบที่ใช้วิเคราะห์ภูมิคุ้มกันที่ได้จากการกระตุ้นด้วยวัคซีนป้องกัน HIV : รายงานการวิจัย. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2013. https://doi.org/10.58837/chula.res.2013.14.

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Introduction and Objective: Among HIV infected donors, the natural history of HIV infection is different and HIV load is the one of factors resulting in the different clinical outcome. We have been characterized HIV infected donors into 2 groups: controllers (HIV loads< 2,000 copies/ml) and noncontrollers (HIV loads > 2,000 copies/ml). In our previous study, we found that controllers who naturally control HIV infection have the higher number of HIV-gag p24 specific T cells than noncontrollers significantly. Thus, we hypothesized that these polyfunctional T cells can effectively suppress
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หังสสูต, ปกรัฐ, та ญาดา ตันสิริ. การวิเคราะห์การยับยั้งการเพิ่มจำนวนของไวรัสเอชไอวีโดยทีเซลล์ : การทดสอบที่ใช้วิเคราะห์ภูมิคุ้มกันที่ได้จากการกระตุ้นด้วยวัคซีนป้องกัน HIV : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2014. https://doi.org/10.58837/chula.res.2014.19.

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Introduction and Objective: Among HIV infected donors, the natural history of HIV infection is different and HIV load is the one of factors resulting in the different clinical outcome. We have been characterized HIV infected donors into 2 groups: controllers (HIV loads <2,000 copies/ml) and noncontrollers (HIV loads >2,000 copies/ml).In our previous study, we founded that controllers who naturally control HIV infection have the higher number of HIV-gag p24 specific T cells than noncontrollers significantly. Thus, We hypothesized that these polyfunctional T cells can effectively suppress
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