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Articoli di riviste sul tema "Viral infection"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 25 luglio 2025

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1

BAR, Hassan. "Hematological Cancer and Viral Infection." Virology & Immunology Journal 8, no. 4 (2024): 1–5. http://dx.doi.org/10.23880/vij-16000353.

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Hematological cancer patients are particularly vulnerable to the morbidity and death caused by viral infections. But, it is not well known how common viral infections are or what effects they have on patients undergoing traditional nontransplant treatment. How severe and how long T-cell-mediated immune suppression is determines the variation in viral infection incidence and prognosis between patient groups. Topics covered in this mini-review article include late CMV infection, new viral pathogens (human herpesvirus-6, BK virus, adenovirus, and human metapneumovirus), advancements in molecular

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2

Kumar, Rajiv, and Fatemeh Mohammadipanah. "Nanomedicine, Viral Infection and Cytokine Stor." International Journal of Clinical Case Reports and Reviews 8, no. 4 (2021): 01–03. http://dx.doi.org/10.31579/2690-4861/156.

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Recently, emerged outbreaks of various viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MERS-CoV, and ZIKA infections, are fatal for human life. These life-threatening infections to public health pointed out as a major cause responsible for initiating severe diseases globally. These viral infections heightened the morbidity rates and thus, it is a deadly fear to human life. Researchers left no stone unturned for searching newer therapeutic targets and remedies to treat these viral infections and outbreaks. Simultaneously, some of the researchers have ga

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3

Han, Mingyuan, Charu Rajput, Tomoko Ishikawa, Caitlin Jarman, Julie Lee, and Marc Hershenson. "Small Animal Models of Respiratory Viral Infection Related to Asthma." Viruses 10, no. 12 (2018): 682. http://dx.doi.org/10.3390/v10120682.

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Respiratory viral infections are strongly associated with asthma exacerbations. Rhinovirus is most frequently-detected pathogen; followed by respiratory syncytial virus; metapneumovirus; parainfluenza virus; enterovirus and coronavirus. In addition; viral infection; in combination with genetics; allergen exposure; microbiome and other pathogens; may play a role in asthma development. In particular; asthma development has been linked to wheezing-associated respiratory viral infections in early life. To understand underlying mechanisms of viral-induced airways disease; investigators have studied

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4

Barroso-González, Jonathan, Laura García-Expósito, Isabel Puigdomènech, et al. "Viral infection." Communicative & Integrative Biology 4, no. 4 (2011): 398–408. http://dx.doi.org/10.4161/cib.16716.

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5

Bose, Avirup, Debabrata Saha, and Naba K. Gupta. "Viral Infection." Archives of Biochemistry and Biophysics 342, no. 2 (1997): 362–72. http://dx.doi.org/10.1006/abbi.1997.0138.

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6

Saha, Debabrata, Shiyong Wu, Avirup Bose, et al. "Viral Infection." Archives of Biochemistry and Biophysics 342, no. 2 (1997): 373–82. http://dx.doi.org/10.1006/abbi.1997.0139.

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7

Schabert, Vernon F., Essy Mozaffari, Yi-Chien Lee, and Roman Casciano. "Double-Stranded DNA (dsDNA) Viral Infections Among Allogeneic Hematopoietic Cell Transplant (HCT) Recipients in the First Year after Transplant." Blood 126, no. 23 (2015): 3296. http://dx.doi.org/10.1182/blood.v126.23.3296.3296.

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Abstract Introduction: Double-stranded DNA (dsDNA) viral infections (including cytomegalovirus, adenoviruses, BK virus, and Epstein-Barr virus) can lead to significant morbidity and mortality among immunocompromised patients following allogeneic hematopoietic stem cell transplant (HCT). The lack of a broad-spectrum antiviral with the safety and tolerability to prevent viral infections poses management challenges for patients at risk of multiple dsDNA viral infections. Using a large US insurance claims database, this study describes the incidence of dsDNA viral infections and co-infections amon

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8

Basmaci, Romain, Philippe Bidet, and Stéphane Bonacorsi. "Kingella kingae and Viral Infections." Microorganisms 10, no. 2 (2022): 230. http://dx.doi.org/10.3390/microorganisms10020230.

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Kingella kingae (K. kingae) is an oropharyngeal commensal agent of toddlers and the primary cause of osteoarticular infections in 6–23-month-old children. Knowing that the oropharynx of young children is the reservoir and the portal of entry of K. kingae, these results suggested that a viral infection may promote K. kingae infection. In this narrative review, we report the current knowledge of the concomitance between K. kingae and viral infections. This hypothesis was first suggested because some authors described that symptoms of viral infections were frequently concomitant with K. kingae in

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9

Uluğ, Mehmet. "A viral infection of the hands: Orf." Journal of Microbiology and Infectious Diseases 03, no. 01 (2013): 41–44. http://dx.doi.org/10.5799/ahinjs.02.2013.01.0078.

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10

Karathanasi, Vassiliki, Malamatenia Bourazani, Christina Orfanou, et al. "Common oral viral infections." ACTA MICROBIOLOGICA HELLENICA 59, no. 1 (2014): 29–37. https://doi.org/10.5281/zenodo.10012687.

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Oral cavity as being an "open gate" of the human body comprises an appropriate field for the establishment of varying infections. Oral viral infections can be either primary and localized or secondary to systematic infection. The most common oral viral infections are caused by herpes viruses, enteroviruses and human papilloma viruses. Among herpes viruses, herpes simplex virus 1(HSV-1), vericella-zoster virus (VZV) and Epstein-Barr virus (EBV) affect the oral cavity more frequently. HSV-1 and VZV appear in the form of vesicles that break leaving secondary painful ulcerations. EBV within the de

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11

Mandelia, Yamini, Gary W. Procop, Sandra S. Richter, Sarah Worley, Wei Liu, and Frank Esper. "2627. Dynamics of Respiratory Viral Co-infections: Predisposition for and Clinical Impact of Viral Pairings in Children and Adults." Open Forum Infectious Diseases 6, Supplement_2 (2019): S916—S917. http://dx.doi.org/10.1093/ofid/ofz360.2305.

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Abstract Background The clinical relevance of respiratory viral co-infections is unclear. Few studies determine epidemiology and impact of specific co-infection pairings. Here we assess the dynamics of respiratory viral co-infections, determine any predisposition for specific pairings to occur and evaluate resulting clinical impact on hospitalization. Methods We reviewed respiratory viral panel results collected at The Cleveland Clinic between November 2013 to Jun 2018. Monthly prevalences, mono-infections and co-infections of 13 viral pathogens were tabulated. Employing a mathematical model w

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12

Cyr, Peggy R., and William Dexter. "Viral Skin Infection." Physician and Sportsmedicine 32, no. 7 (2004): 33–38. http://dx.doi.org/10.3810/psm.2004.07.444.

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13

Dykxhoorn, Derek M., and Judy Lieberman. "Silencing Viral Infection." PLoS Medicine 3, no. 7 (2006): e242. http://dx.doi.org/10.1371/journal.pmed.0030242.

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14

CARROLL, D., P. KAMATH, and L. STEWART. "Congenital viral infection?" Lancet 365, no. 9464 (2005): 1110. http://dx.doi.org/10.1016/s0140-6736(05)74237-9.

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15

Carroll, DN, P. Kamath, and L. Stewart. "Congenital viral infection?" Lancet 365, no. 9464 (2005): 1110. http://dx.doi.org/10.1016/s0140-6736(05)71149-1.

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16

Zeng, Wenwen, and Zhijian J. Chen. "MITAgating Viral Infection." Immunity 29, no. 4 (2008): 513–15. http://dx.doi.org/10.1016/j.immuni.2008.09.010.

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17

Ennis, Chris. "Preventing viral infection." Computer Fraud & Security Bulletin 11, no. 12 (1989): 11–13. http://dx.doi.org/10.1016/0142-0496(89)90145-8.

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18

Charles Povey, R. "Persistent Viral Infection." Veterinary Clinics of North America: Small Animal Practice 16, no. 6 (1986): 1075–95. http://dx.doi.org/10.1016/s0195-5616(86)50130-3.

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19

McIlwain, Benjamin. "Scrambling viral infection." Nature Chemical Biology 19, no. 10 (2023): 1173. http://dx.doi.org/10.1038/s41589-023-01441-z.

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20

Cukuranovic, Jovana, Sladjana Ugrenovic, Ivan Jovanovic, Milan Visnjic, and Vladisav Stefanovic. "Viral Infection in Renal Transplant Recipients." Scientific World Journal 2012 (2012): 1–18. http://dx.doi.org/10.1100/2012/820621.

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Viruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility. Although cytomegalovirus is the most common opportunistic pathogen seen in transplant recipients, numerous other viruses have also affected outcomes. In some cases, preventive measures such as pretransplant screening, prophylactic antiviral therapy, or posttransplant viral monitoring may limit the impact of thes

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21

Tong-Minh, Kirby, Katrijn Daenen, Henrik Endeman, et al. "Performance of the FebriDx Rapid Point-of-Care Test for Differentiating Bacterial and Viral Respiratory Tract Infections in Patients with a Suspected Respiratory Tract Infection in the Emergency Department." Journal of Clinical Medicine 13, no. 1 (2023): 163. http://dx.doi.org/10.3390/jcm13010163.

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FebriDx is a rapid point-of-care test combining qualitative measurements of C-reactive protein (CRP) and Myxovirus Resistance Protein A (MxA) using a disposable test device to detect and differentiate acute bacterial from viral respiratory tract infections. The goal of this study was to investigate the diagnostic accuracy of FebriDx in patients with suspected respiratory tract infections in the emergency department (ED). This was an observational cohort study, performed in the ED of an academic hospital. Patients were included if they had a suspected infection. The primary outcome was the pres

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22

Aksoy, S., H. Harputluoglu, S. Kilickap, et al. "Rituximab-induced viral infections in lymphoma patients." Journal of Clinical Oncology 25, no. 18_suppl (2007): 18509. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.18509.

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18509 Background: Recently, a chimeric mouse human monoclonal antibody, rituximab, has been used successfully to treat cases of B-cell non-Hodgkin’s lymphoma (NHL) and some autoimmune diseases. However, several viral infections related to rituximab have been reported in literature, but not well characterized. Methods: To further investigate this topic, relevant English language studies were identified through Medline. For our search we used the generic name rituximab, and the key phrases virus/virus infection. The references from the identified articles were reviewed for additional sources. Re

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23

Yamaya, Mutsuo. "Virus Infection-Induced Bronchial Asthma Exacerbation." Pulmonary Medicine 2012 (2012): 1–14. http://dx.doi.org/10.1155/2012/834826.

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Infection with respiratory viruses, including rhinoviruses, influenza virus, and respiratory syncytial virus, exacerbates asthma, which is associated with processes such as airway inflammation, airway hyperresponsiveness, and mucus hypersecretion. In patients with viral infections and with infection-induced asthma exacerbation, inflammatory mediators and substances, including interleukins (ILs), leukotrienes and histamine, have been identified in the airway secretions, serum, plasma, and urine. Viral infections induce an accumulation of inflammatory cells in the airway mucosa and submucosa, in

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24

Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. http://dx.doi.org/10.3390/v15091860.

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Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here, we systematically review peer-reviewed literature r

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Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. https://doi.org/10.5281/zenodo.13446073.

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(Uploaded by Plazi for the Bat Literature Project) Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here,

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Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. https://doi.org/10.5281/zenodo.13446073.

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Abstract (sommario):

(Uploaded by Plazi for the Bat Literature Project) Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here,

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27

Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. https://doi.org/10.5281/zenodo.13446073.

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Abstract (sommario):

(Uploaded by Plazi for the Bat Literature Project) Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here,

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Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. https://doi.org/10.5281/zenodo.13446073.

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Abstract (sommario):

(Uploaded by Plazi for the Bat Literature Project) Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here,

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Jones, Brent D., Eli J. Kaufman, and Alison J. Peel. "Viral Co-Infection in Bats: A Systematic Review." Viruses 15, no. 9 (2023): 1860. https://doi.org/10.5281/zenodo.13446073.

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Abstract (sommario):

(Uploaded by Plazi for the Bat Literature Project) Co-infection is an underappreciated phenomenon in contemporary disease ecology despite its ubiquity and importance in nature. Viruses, and other co-infecting agents, can interact in ways that shape host and agent communities, influence infection dynamics, and drive evolutionary selective pressures. Bats are host to many viruses of zoonotic potential and have drawn increasing attention in their role as wildlife reservoirs for human spillover. However, the role of co-infection in driving viral transmission dynamics within bats is unknown. Here,

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Ghafouri-Fard, Soudeh, Bashdar Mahmud Hussen, Hazha Hadayat Jamal, Mohammad Taheri, and Guive Sharifi. "The Emerging Role of Non-Coding RNAs in the Regulation of Virus Replication and Resultant Cellular Pathologies." International Journal of Molecular Sciences 23, no. 2 (2022): 815. http://dx.doi.org/10.3390/ijms23020815.

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Non-coding RNAs, particularly lncRNAs and miRNAs, have recently been shown to regulate different steps in viral infections and induction of immune responses against viruses. Expressions of several host and viral lncRNAs have been found to be altered during viral infection. These lncRNAs can exert antiviral function via inhibition of viral infection or stimulation of antiviral immune response. Some other lncRNAs can promote viral replication or suppress antiviral responses. The current review summarizes the interaction between ncRNAs and herpes simplex virus, cytomegalovirus, and Epstein–Barr i

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31

Khajuria, Atul, Parmila Malik, Jyotsana Khattri, Lalit Singh, and Veeresh VG. "Prevalence of thrombocytopenia in patients with viral infection across different cities in India." Panacea Journal of Medical Sciences 14, no. 3 (2024): 771–74. https://doi.org/10.18231/j.pjms.2024.137.

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Thrombocytopenia, which signifies a low platelet count usually below 150 × 109/L, is a common finding following or during many viral infections. Viral infection innate and adapt immune response where platelets play a passive role in antiviral activity. The patients with viral infection are at risk of developing decreased platelet count and develop the chance of bleeding. The present study designed to find the prevalence of thrombocytopenia in patients with viral infection. : A descriptive cross section survey design used to identify the prevalence rate of thrombocytopenia in patients with vira

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32

Teng, Shaolei, and Qiyi Tang. "ACE2 enhance viral infection or viral infection aggravate the underlying diseases." Computational and Structural Biotechnology Journal 18 (2020): 2100–2106. http://dx.doi.org/10.1016/j.csbj.2020.08.002.

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Wilson, Elizabeth, and David Brooks. "Blockade of chronic type I interferon signaling to control persistent virus infection (P6048)." Journal of Immunology 190, no. 1_Supplement (2013): 49.7. http://dx.doi.org/10.4049/jimmunol.190.supp.49.7.

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Abstract While both immunostimulatory and inhibitory signals are triggered by acute viral infections, persistent infections are characterized by sustained expression of an immunosuppressive program that inhibits antiviral immunity, interferes with viral clearance, and poses a barrier to effective antiviral therapeutics. However, the signals that govern the immunosuppressive program are not understood. Viral infections elicit type I interferons (IFN-I) and these proteins have potent direct antiviral effects. However, IFN-I expression has also been associated with hyper immune activation and inc

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Kwok, Chun Shing, Kirellos Said Abbas, Adnan I. Qureshi, Duwarakan Satchithananda, and Josip Andelo Borovac. "The Impact of Concomitant Diagnosis of Viral Infections on in-Hospital Mortality in Patients Hospitalized with a Diagnosis of Heart Failure in the United States: Insights from the National Inpatient Sample." Viruses 14, no. 11 (2022): 2418. http://dx.doi.org/10.3390/v14112418.

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The impact of viral infections on patients admitted with a diagnosis of heart failure is not well understood. We conducted a retrospective cohort study using data from the National Inpatient Sample in the United States to evaluate the proportion of admissions with a diagnosis of heart failure and viral infections, and we explored how viral infections had impact on in-hospital mortality and length of stay. There were a total of 20,713,539 admission records with a diagnosis of heart failure included in the analysis and 3.8% had a concomitant diagnosis of viral infection. The mean length of stay

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Baz, Rachid, Sagar Lonial, Mohamad Hussein, Arlene S. Swern, and Meletios A. Dimopoulos. "Lenalidomide (LEN) Therapy In Combination with Dexamethasone (DEX) Is Associated with a Low Incidence of Viral Infections." Blood 116, no. 21 (2010): 1950. http://dx.doi.org/10.1182/blood.v116.21.1950.1950.

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Abstract Abstract 1950 Background: Multiple myeloma (MM) is associated with compromised immune function, involving both humoral and cellular mechanisms, and infections are a common problem. The risk of opportunistic infection is higher in relapsed/refractory (RR) MM due to the cumulative immunosuppression associated with prior therapies. Opportunistic viral infections, such as herpes zoster, occur in 5–13% of MM patients (pts) versus < 1% in the general population. LEN improves immune function by enhancing antigen-specific CD8+ T-cell proliferation, cytokine production and cytotoxicity, and

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Fournier, P. E., R. Charrel, and D. Raoult. "Viral Endocarditis or Simple Viral Disseminated Infection?" Clinical Infectious Diseases 53, no. 12 (2011): 1298. http://dx.doi.org/10.1093/cid/cir681.

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Brooks, David G., Dorian B. McGavern, and Michael B. Oldstone. "IL-10 blockade resurrects T cell activity and eliminates a persistent viral infection (46.3)." Journal of Immunology 178, no. 1_Supplement (2007): S61. http://dx.doi.org/10.4049/jimmunol.178.supp.46.3.

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Abstract By definition persistent viral infections are accompanied by immune evasion, and most notably the failure to sustain robust T cell responses, responses that are essential to control of these infections. Identifying and understanding the immunoregulatory mechanisms that direct productive versus abortive T cell responses to viral infections is critical, but currently unclear. Using the model of persistent lymphocytic choriomeningitis virus (LCMV) infection, we found that upregulation of interleukin (IL)-10 early during infection induces T cell exhaustion and directly leads to viral pers

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Imanbayeva, Lira. "A CLINICAL CASE OF A LETHAL OUTCOME OF VIRAL HEPATITIS A AGAINST THE BACKGRAUND OF SEVERE FORM OF HERPES INFECTION." Alatoo Academic Studies 21, no. 3 (2021): 354–59. http://dx.doi.org/10.17015/aas.2021.213.038.

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To date, among viral infections, herpes infections in terms of morbidity occupy a leading position in both children and adults. According to the WHO, this infection is the second most common viral infection after influenza. Herpes viruses are capable of infecting almost all organs and systems of the human body, causing acute, chronic and latent forms of infection. Herpes viruses are hepatotropic and can cause severe fatal hepatitis. In recent decades, not only an increase in morbidity has been observed everywhere, but, unfortunately, there has been an increase in the number of mortalities, whi

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Kane, Melissa, and Tatyana Golovkina. "Common Threads in Persistent Viral Infections." Journal of Virology 84, no. 9 (2009): 4116–23. http://dx.doi.org/10.1128/jvi.01905-09.

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ABSTRACT Most viral infections are self-limiting, resulting in either clearance of the pathogen or death of the host. However, a subset of viruses can establish permanent infection and persist indefinitely within the host. Even though persisting viruses are derived from various viral families with distinct replication strategies, they all utilize common mechanisms for establishment of long-lasting infections. Here, we discuss the commonalities between persistent infections with herpes-, retro-, flavi-, arena-, and polyomaviruses that distinguish them from acutely infecting viral pathogens. The

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Steele, Harrison, Andrew J. Tague, and Danielle Skropeta. "The Role of Sialylation in Respiratory Viral Infection and Treatment." Current Medicinal Chemistry 28, no. 26 (2021): 5251–67. http://dx.doi.org/10.2174/0929867328666210201153901.

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Respiratory infections caused by viruses such as influenza and coronavirus are a serious global problem due to their high infection rates and potential to spark pandemics, such as the current COVID-19 pandemic. Although preventing these infections by using vaccines has been the most successful strategy to date, effective vaccines are not always available. Therefore, developing broad-spectrum anti-viral drugs to treat such infections is essential, especially in the case of immunocompromised patients or for outbreaks of novel virus strains. Sialic acids have been highlighted as a key molecule in

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Tobagar, Mawladad, Saeed Khan Sadaqat, and Karimullah Tobagar. "Viral Hepatitis." Journal for Research in Applied Sciences and Biotechnology 2, no. 6 (2024): 232–40. http://dx.doi.org/10.55544/jrasb.2.6.33.

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Background: The primary goals of conducting surveillance for viral hepatitis are to direct prevention and control activities for these diseases and to evaluate the impact of these activities. Any person with a hepatitis virus infection is a potential source of infection to others. Surveillance would help accomplish the goals by providing information on:  Creating a network of laboratories for diagnosis of viral hepatitis. 2. Monitor trends in incidence of and risk factors for disease. Assess burden of disease 4. Identify infected persons requiring counseling and /or post expo

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Ephraim, Richard K. D. "Prevalence of Hepatitis B, C and HIV infections among haemodialysis patients at the Cape Coast Teaching Hospital, Ghana; A retrospective study." Annals of Medical Laboratory Science 2, no. 1 (2022): 42–51. http://dx.doi.org/10.51374/annalsmls.2022.2.1.0057.

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Background: End stage renal disease (ESRD) patients undergoing hemodialysis could be at a higher risk of acquiring viral infections such as hepatitis B, C (HBV, HCV) and human immunodeficiency virus (HIV). The study investigated the prevalence of HBV, HCV, HIV and identified the determinants of these viral infections among end stage renal disease (ESRD) patients undergoing hemodialysis at the Cape Coast Teaching Hospital (CCTH). Methods: This retrospective hospital-based record review was conducted at the CCTH among 89 patients who underwent hemodialysis in at the renal unit of the hospital. T

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Buonsenso, Danilo, Rosa Morello, Francesco Mariani, et al. "Utility of Rapid Nasopharyngeal Swab for Respiratory Pathogens in the Diagnosis of Viral Infections in Children Hospitalized with Fever: A Prospective Validation Study to Improve Antibiotic Use." Children 11, no. 2 (2024): 225. http://dx.doi.org/10.3390/children11020225.

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Introduction: Fever is among the most common reason for medical assessment and antibiotic prescription in practice. The aim of this study was to evaluate positive and negative predictive values of rapid nasopharyngeal swabs for respiratory pathogens to discriminate viral from bacterial infections. Methods: We prospectively tested children with signs and/or symptoms of infections (e.g., fever, cough, wheezing, suspected urinary tract infection) admitted to a paediatric department. Following discharge, clinical phenotypes were assigned defining a cohort of children having probable/certain viral

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A. P., Krithika, and Ramya R. "Acute Pancreatitis: a late complication of dengue fever." International Journal of Contemporary Pediatrics 5, no. 2 (2018): 676. http://dx.doi.org/10.18203/2349-3291.ijcp20180581.

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Abstract (sommario):

Acute pancreatitis following viral infection is rare in children. Acute pancreatitis complicating viral infections has been described in the form of isolated case reports and small series. The commonly implicated viral infections have been coxsackie virus, hepatitis viruses, mumps, varicella, herpes simplex and cytomegalovirus. However, the etio- pathogenesis of pancreatitis in viral infections remains unclear. Also, the natural history of such pancreatitis has not been adequately studied. Here we present a case of acute pancreatitis following dengue infection.

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Liang, Zhuoxin, Wenqiang Zhang, Yongjiang Jiang, et al. "Clinical Impact of Combined Viral and Bacterial Infection in Pediatric Mycoplasmal Community-Acquired Pneumonia in Western China." Nanoscience and Nanotechnology Letters 12, no. 11 (2020): 1315–22. http://dx.doi.org/10.1166/nnl.2020.3237.

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Abstract (sommario):

Community-acquired pneumonia (CAP) refers to an infection contracted outside the hospital that leads to lung parenchyma inflammation. The clinical characteristics of Mycoplasma pneumoniae (M. pneumoniae) infection in CAP patients were rarely reported. The aim of this study was to describe the clinical characteristic and the impact of co-infections of M. pneumoniae with viral and bacterial pathogens in hospitalized children with CAP in Liuzhou, China. This study retrospects children diagnosed with CAP due to M. pneumoniae infection at a tertiary maternal and child health care hospital. Data rel

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Czuppon, Peter, Florence Débarre, Antonio Gonçalves, et al. "Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action." PLOS Computational Biology 17, no. 3 (2021): e1008752. http://dx.doi.org/10.1371/journal.pcbi.1008752.

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Abstract (sommario):

Repurposed drugs that are safe and immediately available constitute a first line of defense against new viral infections. Despite limited antiviral activity against SARS-CoV-2, several drugs are being tested as medication or as prophylaxis to prevent infection. Using a stochastic model of early phase infection, we evaluate the success of prophylactic treatment with different drug types to prevent viral infection. We find that there exists a critical efficacy that a treatment must reach in order to block viral establishment. Treatment by a combination of drugs reduces the critical efficacy, mos

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Zawitkowska, Joanna, Katarzyna Drabko, Krzysztof Czyżewski, et al. "Viral Infection Profile in Children Treated for Acute Lymphoblastic Leukemia—Results of Nationwide Study." Pathogens 11, no. 10 (2022): 1091. http://dx.doi.org/10.3390/pathogens11101091.

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Abstract (sommario):

Viral infections can be a serious complication of therapy in children with acute lymphoblastic leukemia (ALL). In this study, we focused on the incidence and the profile of viral infection in children with ALL treated in 17 pediatric oncology centers in Poland in the two-year periods of 2018–2019 and 2020–2021. We also compared the frequency of viral infections in 2018–2019 to that in 2020–2021. In 2020–2021, a total of 192 children with ALL had a viral infection during intensive chemotherapy. A total number of 312 episodes of viral infections were diagnosed. The most common infections detecte

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Yao, W., L. Hertel, and L. M. Wahl. "Dynamics of recurrent viral infection." Proceedings of the Royal Society B: Biological Sciences 273, no. 1598 (2006): 2193–99. http://dx.doi.org/10.1098/rspb.2006.3563.

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Abstract (sommario):

In chronic viral infection, low levels of viral replication and infectious particle production are maintained over long periods, punctuated by brief bursts of high viral production and release. We apply well-established principles of modelling virus dynamics to the study of chronic viral infection, demonstrating that a model which incorporates the distinct contributions of cytotoxic T lymphocytes (CTLs) and antibodies exhibits long periods of quiescence followed by brief bursts of viral production. This suggests that for recurrent viral infections, no special mechanism or exogenous trigger is

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Diniz, Edna Maria de Albuquerque, Renata Amato Vieira, Maria Esther Jurfest Ceccon, Maria Akiko Ishida, and Flávio Adolfo Costa Vaz. "Incidence of respiratory viruses in preterm infants submitted to mechanical ventilation." Revista do Instituto de Medicina Tropical de São Paulo 47, no. 1 (2005): 37–44. http://dx.doi.org/10.1590/s0036-46652005000100007.

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Abstract (sommario):

The objectives of this study were to determine the incidence of infection by respiratory viruses in preterm infants submitted to mechanical ventilation, and to evaluate the clinical, laboratory and radiological patterns of viral infections among hospitalized infants in the neonatal intensive care unit (NICU) with any kind of acute respiratory failure. Seventy-eight preterm infants were studied from November 2000 to September 2002. The newborns were classified into two groups: with viral infection (Group I) and without viral infection (Group II). Respiratory viruses were diagnosed in 23 preterm

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Miller, Sara E. "Aids-Associated Viral Infections." Microscopy and Microanalysis 5, S2 (1999): 1098–99. http://dx.doi.org/10.1017/s143192760001881x.

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Abstract (sommario):

Infection with human immunodeficiency virus (HIV) eventually causes a profound decrease in the body's ability to eradicate or control infections with microorganisms, including viruses. Some infections in AIDS patients are due to common organisms which are of little significance in immunocompetent individuals. Other organisms can be harbored continuously, occasionally causing disease, but normally being suppressed after a heightened immune defense; in AIDS patients, these infections can be life-threatening. Further, practices that predispose to HIV infection also permit entry of other organisms

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