Gotowe bibliografie tematyczne / Fetal teratogenicity

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Gotowa bibliografia na temat „Fetal teratogenicity”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Fetal teratogenicity"

Pop, Lucian, Nicolae Bacalbasa, Irina Balescu, Vlad Dima, and Roxana Elena Bohiltea. "Retinoids and teratogenicity." Romanian Journal of Pediatrics 70, no. 4 (2021): 219–20. http://dx.doi.org/10.37897/rjp.2021.4.3.

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For more than 30 years, retinoids have been used for acne treatment also their teratogenic effects are widely known. For any woman at a fertility age and under retinoid treatment, a contraception program should be in place. Pregnancy should be postponed until the completion of treatment and one month afterwards. Multiple fetal abnormalities are directly linked to isotretinoin.

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Cohen-Kerem, Raanan, and Gideon Koren. "Antioxidants and fetal protection against ethanol teratogenicity." Neurotoxicology and Teratology 25, no. 1 (2003): 1–9. http://dx.doi.org/10.1016/s0892-0362(02)00324-0.

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Chawla, Dr Sumit Pal Singh, Dr Sarabjot Kaur, Dr Mohit Garg, Dr Gurrajan Nikhanj, and Dr Gurveer Kaur. "Pregnancy with Epilepsy." Scholars Journal of Applied Medical Sciences 10, no. 7 (2022): 1073–77. http://dx.doi.org/10.36347/sjams.2022.v10i07.007.

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Epilepsy (Seizure disorder) is one of the most common neurological conditions encountered in pregnancy. The management of epilepsy during pregnancy is quite challenging. The goal of treatment is optimal seizure control with minimal or no in-utero fetal exposure to AEDs in order to minimize the risk of teratogenicity.

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Jain, Soniya A., Madhavi Awale, Sulabha Pathak, Geeta Vanage, Vandana B. Patravale, and Shobhona Sharma. "Teratogenicity of Artemether–Clindamycin Nanostructured Lipid Carriers in Rats." International Journal of Toxicology 35, no. 4 (2016): 420–28. http://dx.doi.org/10.1177/1091581816652605.

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Currently, artemisinin-based combination therapy is considered the best option in the treatment of malaria. However, toxicity of artemisinins limits their use in pregnancy. In the absence of sufficient toxicity data, the World Health Organization recommends that artemisinins are not to be used in the first trimester of pregnancy and can be used only in second and third trimesters, when other treatments are not available. We have recently observed that drugs loaded in nanolipid carriers are selectively taken up in Plasmodium-infected erythrocytes with a concomitant reduction in the dose require

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Nasreen, Noor Suhail Ahmed Almani Shafaq Nazia Muhammad Iqbal Shah* Aatir H. Rajput Muhammad Muneeb Syed Jehangir and Shahrukh Shaikh. "CROSS-SECTIONAL ANALYSIS OF DANGERS INHERENT WITH PRE AND POST PARTUM USE OF ANTICOAGULATION THERAPY." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1422–25. https://doi.org/10.5281/zenodo.817584.

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Background:The rate of thrombotic mal-events is three-fold to five-fold greater during pre-partum and post-partum phases than at any other time in a women’s life and thus many women receive anticoagulant therapy during pregnancy and puerperium, despite evidence suggesting that this therapy may pose grave danger to the well-being of the fetus and the mother. Objective: This research hopes to highlight the dangers inherent (to the mother and fetus) with the pre-partum and post-partum use of anti-coagulation therapy. Methodology This retrospective analysis is built upon the primary data, availabl

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Hari, Dr Anupama, Dr Bushra Shereen, and Dr J. Sreeja Shraddha. "Anti-Neoplastic Drug Exposure in Pregnancy and Fetal Haemorrhage: A Rare Teratogenicity." Scholars International Journal of Obstetrics and Gynecology 5, no. 3 (2022): 130–32. http://dx.doi.org/10.36348/sijog.2022.v05i03.011.

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Anti-neoplastic drugs are known to have teratogenic effects on the fetus. In this case report we are presenting a case of a patient who got operated for breast carcinoma, conceived while on chemotherapy and underwent termination of pregnancy in the second trimester. Fetal haemorrhage and ecchymosis lead to further evaluation of the case, which revealed fetal thrombocytopenia, a rare teratogenic effect of the anti-neoplastic drugs.

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Gupta, Rohini, Brij Mohan Gupta, and Apeksha Gupta. "Impact of educational intervention on the awareness of undergraduate medical students towards teratogenicity: an observational study." International Journal of Basic & Clinical Pharmacology 7, no. 9 (2018): 1842. http://dx.doi.org/10.18203/2319-2003.ijbcp20183500.

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Background: The term teratogenicity is defined as any morphological, behavioral or biochemical effect induced during embryonic life or fetal life detected at birth or later. the factors that lead to teratogenicity include both non-genetic and genetic factors. The objective of the present study was to assess the impact of educational interventions on the awareness of undergraduate medical students towards teratogenicityMethods: The present study was a questionnaire-based comparative observational study carried out at Department of Pharmacology and Therapeutics, Government Medical College, Jammu

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Koren, Gideon, and Sheri Nickel. "Sources of bias in signals of pharmaceutical safety in pregnancy." Clinical & Investigative Medicine 33, no. 6 (2010): 349. http://dx.doi.org/10.25011/cim.v33i6.14585.

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Every year scores of new pharmaceuticals enter the market, almost never with human fetal safety data. Such data typically accumulate during the first years of clinical use, in the form of case reports, case series, prospective and retrospective cohorts and case control studies. All of these methods suffer from serious sources of bias, often leading to alarming signals of teratogenicity that are later found to be false. This review highlights major sources of bias, including the bias against the null hypothesis in its different forms, ascertainment and recall bias, in fetal exposure to pharmace

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Olegård, Ragnar. "Alcohol and Narcotics:Epidemiology and Pregnancy Risks." International Journal of Technology Assessment in Health Care 8, S1 (1992): 101–5. http://dx.doi.org/10.1017/s0266462300012988.

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AbstractAmong alcohol and narcotics, alcohol is most comprehensively documented as a teratogen. However, for all other narcotics, data are continuously accumulating, convincingly displaying the teratogenic effects. The proportions between “somatic” teratogenicity and “behavioral” teratogenicity vary between the different agents. Preventive work in prenatal clinics and among social workers, as well as objective mass media attention to the problem, seems to have lowered the incidence of severe fetal alcohol syndrome where the above-mentioned activities have been practiced. The female alcohol con

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Flentke, George R., and Susan M. Smith. "The avian embryo as a model for fetal alcohol spectrum disorder." Biochemistry and Cell Biology 96, no. 2 (2018): 98–106. http://dx.doi.org/10.1139/bcb-2017-0205.

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Prenatal alcohol exposure (PAE) remains a leading preventable cause of structural birth defects and permanent neurodevelopmental disability. The chicken (Gallus gallus domesticus) is a powerful embryological research model, and was possibly the first in which the teratogenicity of alcohol was demonstrated. Pharmacologically relevant exposure to alcohol in the range of 20–70 mmol/L (20–80 mg/egg) disrupt the growth of chicken embryos, morphogenesis, and behavior, and the resulting phenotypes strongly parallel those of mammalian models. The avian embryo’s direct accessibility has enabled novel i

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Rozprawy doktorskie na temat "Fetal teratogenicity"

Henrique, Breno Schumaher. "Efeitos tóxicos da \"Ipomoea carnea\" em caprinos. II - estudos de teratogenicidade." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-18092007-094808/.

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A Ipomoea carnea, pertencente à família das Convolvulaceae, é uma planta tóxica que tem ampla distribuição pelo país, tendo como principal princípio ativo a suainsonina. É uma das poucas plantas que se conserva verde durante a seca, podendo servir como fonte de matéria verde para bovinos, ovinos e caprinos, é nesse período, quando normalmente ocorrem os casos de intoxicação, sendo a espécie caprina a mais susceptível. Até o momento, não há relatos sobre efeitos tóxicos desta planta em conseqüência da possível passagem transplacentária da suainsonina. Assim, o objetivo do presente estudo foi av

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Napier, J. D., Phillip R. Scheuerman, and Rebecca A. Pyles. "The Effect of Water Hardness and Humic Acid on the Teratogenicity and Toxicity of Atrazine Using FETAX." Digital Commons @ East Tennessee State University, 1998. https://dc.etsu.edu/etsu-works/2920.

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Summers, Brooke Lee. "Ethanol-related teratogenicity and neurobehavioural impairments: influence of dietary zinc supplementation during pregnancy." Thesis, 2009. http://hdl.handle.net/2440/55042.

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Ethanol consumption during pregnancy can result in wide range of negative outcomes, including pre-and post-natal mortality, growth retardation, physical abnormalities and brain deficits, manifested as behavioural impairments. These outcomes can result from “binge-drinking” (generally defined as >5 standard drinks on a single occasion) or chronic ethanol consumption. Ethanol-induced zinc (Zn) deficiency is one of the mechanisms proposed as a cause of ethanol teratogenicity. We have previously demonstrated in mice that ethanol exposure on gestational day (GD)8 (during organogenesis) can alter

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Summers, Brooke Lee. "Ethanol-related teratogenicity and neurobehavioural impairments: influence of dietary zinc supplementation during pregnancy." 2009. http://hdl.handle.net/2440/55042.

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Wijayawardhane, Nayana. "Therapeutic effects of aniracetam on cognitive deficits induced by ethanol teratogenicity a novel treatment approach through synaptic AMPA receptor modulation /." 2007. http://repo.lib.auburn.edu/2007%20Spring%20Dissertations/WIJAYAWARDHANE_NAYANAKANTHI_21.pdf.

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Carey, Luke Charles. "Ethanol teratogenicity : the aetiological importance of zinc and metallothionein / by Luke Charles Carey." Thesis, 2002. http://hdl.handle.net/2440/21909.

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"August 2002" Bibliography: leaves 141-176. ix, 179 leaves : ill. (some col.) ; 30 cm Changes in maternal-foetal zinc homeostasis resulting in a foetal deficiency may be an important contributing factor in ethanol-realted teratogenicity. Ethanol induces expression of hepatic metallothionein, causing zinc transfer from the plasma to the liver. Rodent studies show that changes in plasma zinc correlate with a high incidence of abnormal fetuses in MT+/+ mice. Demonstrates a clear link between maternal hepatic MT induction, decreased foetal zinc supply, and teratogenicity, which has major

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Carey, Luke Charles. "Ethanol teratogenicity : the aetiological importance of zinc and metallothionein / by Luke Charles Carey." 2002. http://hdl.handle.net/2440/21909.

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"August 2002" Bibliography: leaves 141-176. ix, 179 leaves : ill. (some col.) ; 30 cm Title page, contents and abstract only. The complete thesis in print form is available from the University Library. Changes in maternal-foetal zinc homeostasis resulting in a foetal deficiency may be an important contributing factor in ethanol-realted teratogenicity. Ethanol induces expression of hepatic metallothionein, causing zinc transfer from the plasma to the liver. Rodent studies show that changes in plasma zinc correlate with a high incidence of abnormal fetuses in MT+/+ mice. Demonstrates

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Książki na temat "Fetal teratogenicity"

E, Norton Dale, and Washington (State). Toxics Cleanup Program., eds. Frog embryo teratogenesis assay Xenopus (FETAX) for soil toxicity screening. Environmental Investigations and Laboratory Services Program, Washington State, Dept. of Ecology, 1996.

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Lynch, Tara A., and J. Christopher Glantz. Seizure Medications Effects on Fetus, Neonate, and Lactation. Edited by Emma Ciafaloni, Cheryl Bushnell, and Loralei L. Thornburg. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190667351.003.0021.

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Medication use in pregnancy requires a careful balance between the risks of fetal teratogenicity and the maternal benefits of disease treatment. For women with epilepsy, there are many antiepileptic medications available for use in pregnancy. Each varies in their safety profile, risk for fetal anomalies, and effectiveness of seizure control. In most scenarios, the benefits of maternal treatment outweigh the risk of fetal effects, especially in cases of refractory epilepsy or severe disease. Many of the newer anti-epileptic drugs appear to have less teratogenic risk than the older medications.

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Berman, David, and Ben Touré. Neurosurgery in Pregnancy. Edited by David E. Traul and Irene P. Osborn. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850036.003.0022.

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Pregnancy is a time of significant physiologic change that affects the vast majority of organ systems. Pregnant patients occasionally present for nonobstetric surgery, with complication rates of the procedure increased as well as the potential for fetal loss or damage as a result of the underlying disease process. Typical steps in diagnosis (such as imaging modalities) often need to be adjusted in pregnancy, and the medical or surgical treatment of neurologic disease will often change as well. A thorough understanding of pregnancy physiology, pharmacology, and teratogenicity will be important

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Części książek na temat "Fetal teratogenicity"

Bertrand, Jacquelyn, and Elizabeth Parra Dang. "Fetal Alcohol Spectrum Disorders: Review of Teratogenicity, Diagnosis and Treatment Issues." In Handbook of Children with Special Health Care Needs. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-2335-5_12.

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Akan, Ayse Sule. "Advanced Cardiac Life Support in Pregnancy." In Special Circumstances in Resuscitation. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358923.3.

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Cardiopulmonary arrest during pregnancy is a rare occurrence. Approximately 10% of maternal deaths are attributed to cardiopulmonary arrest. The AHA guideline advises manually placing the uterus in the left lateral position during pregnant resuscitation and perimortem cesarean section. While there are many causes of cardiopulmonary arrest in the general population, in pregnant patients, causes can arise from pre-existing conditions as well as physiopathological conditions induced by pregnancy. Managing cardiopulmonary arrest during pregnancy is a challenging clinical situation. While maternal

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Islas-Flores, Hariz, Itzayana Pérez-Alvaréz, and Leobardo M. Gómez-Oliván. "Evaluation of Teratogenicity of Pharmaceuticals Using FETAX." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7883-0_15.

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Güngördü, Abbas, and Duygu Ozhan Turhan. "Biochemical Studies to Understand Teratogenicity and Lethality Outcomes in Modified-FETAX." In Methods in Molecular Biology. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3625-1_19.

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Bharadwaj, Shobana, and Jessica Galey. "Anesthesia in a Pregnant Patient Presenting for Urgent Nonobstetric Surgery." In Anesthesiology: A Problem-Based Learning Approach, edited by Tracey Straker and Shobana Rajan. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850692.003.0028.

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For obstetric patients undergoing nonobstetric surgeries, the anesthesiologist has to take into consideration both maternal and fetal safety during the pre-, intra-, and postoperative periods. The goal of the anesthetic management should be to apply maternal physiologic changes, avoid teratogenic agents, avoid decreased uteroplacental perfusion and/or fetal oxygenation, and prevent preterm labor. Decisions on the timing of the procedure and intraoperative fetal and uterine monitoring must be multidisciplinary. The chapter uses a case study of a 24-year-old woman who is admitted at 33 weeks ges

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Salimi, Nayema K., and Kristen L. Fardelmann. "Pregnant Patient for Non-Obstetric Surgery." In Perioperative Medicine, edited by Deborah C. Richman, Debra D. Pulley, and Adriana D. Oprea. Oxford University PressNew York, 2025. https://doi.org/10.1093/med/9780190902001.003.0031.

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Abstract Non-obstetric surgery occurs in up to 2% of all pregnancies in the United States and most commonly involves abdominal and orthopedic procedures. A multidisciplinary approach to care including experts in surgery, obstetrics, anesthesia, and neonatology provides the framework to optimize maternal and fetal outcomes. Medically necessary surgery in the pregnant patient should never be delayed because delaying care is associated with significant maternal and fetal morbidity and mortality. Although significant concern regarding anesthetic exposure in pregnancy and the potential for adverse

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Walter, Elizabeth A., and C. Neill Epperson. "Psychopharmacology during pregnancy: infant considerations." In Pediatric Psychopharmacology: Principles and Practice. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780195141733.003.0048.

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Abstract Over 10 million women in the United States will suffer from the symptoms of mental illness during their childbearing years (Bourdon et al., 1992; U.S. Census Bureau, 2000) and more than 50% of pregnancies are unplanned. These two facts emphasize the importance of educating women’s health care providers regarding the risks associated with mental illness and the medications used to treat these disorders. As all psychoactive medications readily cross the placenta, the impact on the fetus of any medication prescribed to a pregnant woman must be considered and discussed. Documentation that

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Ainsworth, Sean. "Maternal medication and its effect on the baby." In Neonatal Formulary, edited by Sean Ainsworth. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198840787.003.0037.

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All too often the pregnant or breastfeeding mother is told that she cannot receive a drug because the manufacturer has advised against its use. Such information is usually derived from the Summary of Product Characteristics and reflects a lack of information of such use during the early stages of drug development and licensing. These statements are always cautious, seldom very informative, and often merely designed to meet the minimum requirement laid down by the licensing authority. While there are a small number of drugs whose use during pregnancy and lactation is extremely unwise, for most

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Mudgal, Arya, Payal Rani Chaudhary, and Yogesh Joshi. "A CONCISE OVERVIEW ON TERATOGENIC DRUGS." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 10. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bgpn10p2ch2.

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A small percentage of documented congenital malformations with a recognised aetiology, about 1%, are problems related to pharmacological therapy. This shows that responsible and cautious drug use is a viable way of prevention among fertile women, especially pregnant women. It takes careful consideration of both experimental data from animals and human experience to identify a drug's teratogenic effect. 40% of pregnancies are unplanned, therefore it stands to reason that any medication with teratogenic potential should only be administered under close medical supervision. Also, adequate awarene

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