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1

Shireen Farhana. S, Usharani Boopathy, Shobana Chandrasekar, and Rohini Durairaj. "Qualitative And Quantitative Analysis of Cinnamomum Tamala Leaf Extract." Journal of Advanced Zoology 44, S5 (2023): 3071–81. http://dx.doi.org/10.17762/jaz.v44is5.2390.

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Objective: The purpose of the study is to assess the properties and bioactive components of Cinnamomum tamala leaves. Methods: The leaves of Cinnamomum tamala were extracted. Different experimental methods have been used to study the phytochemicals (qualitative and quantitative). The phytochemical screening was evaluated in different extractions such as aqueous, hexane, ethanol, petroleum ether and hydroethanolic to compare the solubility of various bioactive components. Further, high performance liquid chromatography (HPLC) and gas chromatography mass spectrometry (GC-MS) were also performed
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Zouheira, Djamila, Sylvie Lea Wansi Ngnokam, Sylviane Laure Poualeu Kamani, et al. "In Vitro Antilipidic and Antithrombotic Activities of Plectranthus glandulosus (Lamiaceae) Leaves Extracts and Fractions." BioMed Research International 2022 (February 7, 2022): 1–14. http://dx.doi.org/10.1155/2022/4145659.

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Objective. The present study investigated the effect of the leaves extracts and fractions of Plectranthus glandulosus on the inhibition of pancreatic lipase, cholesterol esterase, adipocytes lipid uptake, and antithrombotic activity which may be important in atherosclerosis development. Methods. Aqueous, ethanolic, and hydroethanolic extracts of Plactranthus glandulosus were prepared by maceration. The hydroethanolic extract was fractionated into n-hexane, ethylacetate, and n-butanol fractions and their inhibition of pancreatic lipase, cholesterol esterase, adipocytes lipid uptake, and antithr
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Ouattara, Anzoumana Lassinan, Ouattara Abou, Dominique Konan Tano, and Akissi Jeanne Koffi. "Phenolic Compound Content and Antioxidant Activity of Extracts from the Leaves of Anogeissus leiocarpus (Combretaceae), a Plant Used in the North of Côte d'Ivoire for the Traditional Treatment of Gastrointestinal Disorders in Broiler Chickens." International Journal of Biochemistry Research & Review 33, no. 4 (2024): 52–61. http://dx.doi.org/10.9734/ijbcrr/2024/v33i4869.

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Anogeissus leiocarpus (Combretaceae) (DC.) Guill. & Perr. is a plant found in West Africa, from Senegal to Cameroon and extending to Ethiopia and East Africa. In the north of Côte d’Ivoire, this plant is commonly used by livestock farmers to treat various pathologies, including digestive and gastrointestinal disorders. The aim of this study was to determine the phenolic compound content and antioxidant properties of 70% hydroethanol and aqueous extracts of A. leiocarpus’ leaves. Phenolic compound contents were determined by spectrophotometric methods. Antioxidant activities were assessed u
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EVENAMEDE, Kodjo Selom, Yaovi Samuel APETI, Mamatchi MELILA, Kafui KPEGBA, Amegnona AGBONON, and Oudjaniyobi SIMALOU. "Phytochemical Study and Evaluation of the Nutritional Potential of Glyphaea brevis Leaves from the Flora of Togo." Chemical Science International Journal 34, no. 3 (2025): 24–37. https://doi.org/10.9734/csji/2025/v34i3965.

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Glyphaea brevis is a food plant used in traditional medicine to treat hypertension and a number of infectious diseases. It has been the subject of very few studies and there is little data on its nutritional value. The aim of the present study is therefore to exploit the leaves of Glyphaea brevis from Togolese flora. Aqueous and hydroethanolic extracts were obtained by maceration of leaf powder. Phytochemical tests and polyphenol and flavonoid assays were carried out using colorimetric methods. Antioxidant activity was assessed in vitro using the DPPH radical scavenging test and the FRAP test.
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Rahayu, Ika, Susana Elya Sudrajat, Sancnia Sancnia, Monica Puspasari, and Kris Herawan Timotius. "The Phytochemical constituents and biological activities of sungkai (Peronema canescens Jack) leaves hydroethanolic extracts." JPBIO (Jurnal Pendidikan Biologi) 9, no. 1 (2024): 123–32. http://dx.doi.org/10.31932/jpbio.v9i1.3398.

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Peronema canescens, Jack commonly known as "sungkai," has been traditionally used as a herbal medicine for various health conditions. This study aimed to explore the bioactive compound of the P. canescens leaves hydroethanolic extract, along with assessing its antioxidant and antimutagenic properties. Liquid chromatography-mass spectrometry (LC-MS) was utilized for phytochemical analysis of the hydroethanolic extracts, while antioxidant activity was evaluated through the DPPH radical scavenging method. Quantification of total phenolic and flavonoid content was achieved via colorimetric analysi
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Ni Putu Ermi Hikmawanti, Hayati, and Yeni Andriyani. "Total Flavonoid Content in Hydro-ethanolic Extract of Sauropus androgynus (L.) Merr Leaves from Three Regions with Different Altitude." Jurnal Jamu Indonesia 6, no. 2 (2021): 61–67. http://dx.doi.org/10.29244/jji.v6i2.195.

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Sauropus androgynus (L.) Merr (Phyllanthaceae), also known as katuk in Indonesia, is a plant that grows in tropical climates. The study aimed to determine the total flavonoid levels of hydroethanolic extract of katuk leaves from three regions with different altitudes. Dried katuk leaves were macerated using hydroethanolic (the mixture of ethanol:H2O (7:3, v/v)) as solvent extraction at room temperature. Determination of flavonoid levels was carried out by the colorimetry method using AlCl3 reagent. Quercetin was used as a reference. A UV-Visible spectrophotometer measured the absorbance at the
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Tokoudagba, Kossi Jean Marie D., Alban G. Houngbèmè, Habib Ganfon, et al. "Isolation of Biomolecules from the Leaves of Lecaniodiscus cupanoides (Sapindaceae), a Plant used in Traditional Medicine in Benin." Asian Journal of Applied Chemistry Research 14, no. 3 (2023): 39–47. http://dx.doi.org/10.9734/ajacr/2023/v14i3269.

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The aim of the present study was to identify the structure of the bioactive molecules in the active ethyl acetate fraction of the hydroethanolic extract of Lecaniodiscus cupanoides (Sapindaceae), a Beninese plant used in the treatment of microbial infections. We prepared the hydroethanolic extract from powdered dried leaves. We fractionated the hydroethanol extract using the liquid-liquid extraction method with solvents of increasing polarity. The active ethyl acetate fraction obtained after bioguided fractionation of the hydroethanol extract on bacterial strains was purified by a series of at
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Moyo, Batanai, and Stanley Mukanganyama. "The Anticandidal and Toxicity Properties of Lampranthus francisci." Journal of Mycology 2015 (October 15, 2015): 1–15. http://dx.doi.org/10.1155/2015/898202.

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Fungal infections have been rising due to the increasing number of immunocompromised patients and intensive use of some antifungal agents. Lampranthus francisci is an ornamental succulent plant. In Zimbabwe, the fresh sap from the leaves is used to treat fungal scalp infections. The activity of L. francisci fresh and dry acetone, ethanol, hydroethanolic, and aqueous extracts against Candida albicans and Candida krusei was determined. Mouse peritoneal cavity cells and sheep red blood cells were used to investigate L. francisci’s toxicity profile. The hydroethanolic extracts were the most effect
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O R, Kasthuri, and Ramesh B. "PHYTOCHEMICAL SCREENING AND IN VITRO ANTIOXIDANT ACTIVITIES OF LEAF EXTRACTS OF ALTERNANTHERA BRASILIANA (L). KUNTZE AND ALTERNANTHERA BETTZICKIANA REGEL." Asian Journal of Pharmaceutical and Clinical Research 11, no. 6 (2018): 266. http://dx.doi.org/10.22159/ajpcr.2018.v11i6.25136.

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Objectives: The present study was carried out to determine the phytochemical constituents and in vitro antioxidant activities of leaf extracts of Alternanthera brasiliana (L). Kuntze (A. brasiliana) and Alternanthera bettzickiana regel (A. bettzickiana).Methods: Preliminary phytochemical screening was performed in petroleum ether, chloroform, acetone, ethanol, hydroethanolic and water extracts of leaves of A. brasiliana and A. bettzickiana. The level of alkaloids, flavonoids, total phenolic content, tannins, Vitamin C, Vitamin E, GSH, and total proteins were determined in hydroethanolic, ethan
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Antunes, Kátia Avila, Débora da Silva Baldivia, Paola dos Santos da Rocha, et al. "Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/4353604.

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Obesity is a worldwide epidemic that reduces life expectancy; therefore, the search for new alternative and effective treatments is ongoing. The aim of the present investigation was to identify the chemical compounds in the hydroethanolic extract of leaves of Jacaranda decurrens subsp. symmetrifoliolata and to evaluate their toxicity and antiobesity effects. High-performance liquid chromatography was used to identify the chemical constituents, and acute toxicity was evaluated in rats treated with doses of 2 and 5 g·kg−1 body mass. The antiobesity effect was determined in rats with hypercaloric
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Mbaye, Sène, Diouf Ibrahima, Ba Awa, et al. "<b>Antisickling effects of hydroethanolic extract of <i>Oxytenanthera abyssinica</i> leaves</b>." National Journal of Physiology, Pharmacy and Pharmacology 15, no. 6 (2025): 314. https://doi.org/10.5455/njppp.2025.v15.i6.3.

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Background: Sickle cell disease is a hereditary hemoglobinopathy. It is characterized by the presence of abnormal hemoglobin S (HbS) levels at high concentrations in red blood cells. Aim: This study aimed to investigate the potential of a hydroethanolic extract from Oxytenanthera abyssinica leaves to inhibit red blood cell sickling in individuals with sickle cell trait (HbAS) and sickle cell disease (HbSS). Methods: Ten (10) grams of powdered Oxytenanthera abyssinica leaves were macerated in 100 mL of a 60% hydroethanolic solution. Following filtration, the macerate was concentrated using a ro
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Sibri, Jean François, Joël Akakpo-Akue, Stéphane Claver Vanié, Tatiana Kangah Mireille Kple, M'Bèféhê Soro, and Obou Constantin Okou. "Phytochemical Evaluation and Determination of the Content of Some Natural Antioxidants (Polyphenols and Flavonoids) from Ficus Capensis, Newbouldia laevis and Carpolobia lutea." Asian Journal of Biology 19, no. 4 (2023): 29–37. http://dx.doi.org/10.9734/ajob/2023/v19i4374.

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Scientific interest in the search for natural antioxidants (secondary metabolites) from medicinal plants has increased considerably in recent years, due to the involvement of free radicals in the genesis of many diseases. The aim of the present study is to determine qualitatively and quantitatively the secondary metabolites of aqueous and hydroethanol extracts from the leaves of the medicinal plants under investigation. Qualitative determination is based on staining and/or precipitation reactions, while quantitative determination is based on the assay of secondary metabolites. The results of t
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Fanta Yadang, Sabine Adeline, Germain Taiwe Sotoing, Katoucha Sidoine Ngatcha Zouakeu, et al. "Quantification of Bioactive Compounds and Evaluation of the Antioxidant Activity of Carissa edulis Valh (Apocynaceae) Leaves." Scientific World Journal 2019 (May 15, 2019): 1–9. http://dx.doi.org/10.1155/2019/7549620.

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Carissa edulis is a plant used in the management of oxidative stress and inflammatory related disorders such as malaria, rheumatism inflammation, and cardiovascular diseases. The present study evaluates the total phenolic content, antioxidant capacity (DPPH, ABTS, and FRAP), and the bioactive compounds present in the various extracts of C. edulis (HEC, MEC, AEC, and PC). An HPLC analysis determined the different compounds present in the extracts. High concentration of total phenolic content was observed in aqueous and methanolic extracts more than in the hydroethanolic extract though not signi
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14

Ayéna, Aimé Cézaire T., Kossivi Dosseh, Kokou Idoh, Amegnona Agbonon, and Messanvi Gbeassor. "Comparative Physicochemical Screening and Toxicology of Hydroethanol Extracts of the Parts of Pterocarpus santalinoides l’Hér. ex DC. (Fabaceae) in Wistar Rats." Scientific World Journal 2022 (February 25, 2022): 1–7. http://dx.doi.org/10.1155/2022/5953094.

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Aims. The aim of this study was to compare the phytochemical profile and acute and chronic toxicity of hydroethanolic extracts of three parts of P. santalinoides. Methods. Seven major chemical groups (alkaloids, flavonoids, saponosides, coumarins, tannins, triterpenes, and steroids) were studied. The single dose limit test of 5000 mg/kg body weight was used to evaluate the acute toxicity of each organic extract. Subacute toxicity was evaluated after daily oral doses of 500 and 1000 mg/kg body weight were administered to rats for 28 days. Results. At a single dose of 5000 mg/kg, none of the ext
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Rabha, Kushal, Pritam Mohan, Sumitra Debnath, et al. "Formulation and Evaluation of Hydroethanolic and Chloroform Extracts of Zanthoxyllum oxyphyllum for Analgesic and Wound Healing Activities." Advances in Research 26, no. 2 (2025): 33–44. https://doi.org/10.9734/air/2025/v26i21272.

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Zanthoxylum oxyphyllum under the family Rutaceae, commonly known as Mezenga in Assam grow in tropical and temperate regions. Hydroethanolic and chloroform extracts of leaves of the plant were screened for analgesic activity and wound healing property by hot plate test and excision, incision wound model. The acute toxicity study revealed that both the plant extracts were non-toxic and safe for oral dosing. Both the extracts were non-sensitizing to rabbit skin and caused very little or no irritation in intact and damaged skin rabbits treated with single and multiple doses. Irritation scores did
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Itou RDG, Elion, Etou Ossibi AW, Morabandza CJ, Kiessé D.S., Mayela Nkouka S.H.J, and Abena AA. "Toxicité Aigüe Et Effets Des Extraits Des Feuilles De Cogniauxia Podolaena Bail. (Cucurbitaceae) Sur L’excrétion Fécale Et La Motilité Intestinale." European Scientific Journal, ESJ 13, no. 27 (2017): 355. http://dx.doi.org/10.19044/esj.2017.v13n27p355.

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This work aims to estimate acute toxicity and to evaluate the effects of the aqueous and hydroethanolic extracts of leaves (Cucurbitaceae) of Cogniauxia podolaena on the fecal excretion and the intestinal motility. The estimation of the acute toxicity was made by oral administration of the aqueous and hydroéthanolique extracts in the doses of 2000 and 500 mg/kg in mice in order to determine the lethal dose 50 (LD50) and the experimental doses. No sign of toxicity was observed with the hydroethanolic extract in mice. The aqueous extract of Cogniauxia podolaena is slightly toxic with a lethal do
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Pauline, Deguenon Memonsso Pierrette, Houngbeme Gouton Alban, Ahoyo Carlos Cédric, Ombouma Joanna Grâce, Gbaguidi Ahokanou Fernand, and Houinato Marcel Romuald Benjamin. "Chemical Identification, In vitro Antidiarrheal Potential, and Toxicological Study of the Leaves of Combretum grandiflorum G. Don (Combretaceae), a Beninese Medicinal Plant." International Journal of Plant & Soil Science 35, no. 22 (2023): 954–77. http://dx.doi.org/10.9734/ijpss/2023/v35i224207.

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Combretum grandiflorum G. Don is traditionally used in ethnic medicines for the treatment of different diseases in Benin. Despite its wide use, no studies have been undertaken on its potential toxicity. The study was designed to assess the antimicrobial activity and potential toxicity of aqueous and hydroethanolic extracts of C. grandiflorum.&#x0D; Qualitative phytochemistry was carried out by a differential staining or precipitation method. The antibacterial and antifungal effects were evaluated by the solid medium diffusion method. Cytotoxicity was evaluated on Artemia salina larvae while ac
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Fokam Tagne, Michel Archange, Hypolyte Akaou, Paul Aimé Noubissi, et al. "Effect of the Hydroethanolic Extract of Bixa orellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice." Gastroenterology Research and Practice 2019 (December 1, 2019): 1–8. http://dx.doi.org/10.1155/2019/6963548.

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Objective. The treatment of diarrheal diseases is a serious problem in developing countries, where population generally uses medicinal plants. The leaves of Bixa orellana have been reported to be traditionally used in the treatment of diarrhea by local people in the district of Khulna in Bangladesh. The aim of this study was to investigate the effects of the hydroethanolic extract of Bixa orellana leaves on castor oil-induced diarrhea in mice. Methods. The powder of the leaves of Bixa orellana was macerated in ethanol/water mixture (20/80) for 48 hours and then filtered. The filtrate obtained
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NOUDAMADJO, Amandine, Bénédicta KPADONOU-KPOVIESSI, Bienvenu GLINMA, et al. "Phytochemical Profiling and Evaluation of Antioxidant and Anti-inflammatory Activities In vitro of Newbouldia laevis and Flueggea virosa Leaf Extracts." Chemical Science International Journal 34, no. 3 (2025): 87–98. https://doi.org/10.9734/csji/2025/v34i3970.

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Traditional medicine use has surged over the past 20 years, with many people using it to treat various health issues. Ethnobotanical and pharmaceutical surveys revealed their application in many areas. Ethnobotanical and pharmaceutical surveys have revealed their application in many areas. Analyzing the antioxidant and anti-inflammatory properties and quantifying the polyphenol, flavonoid, and tannin contents of the methanolic and hydroethanolic extracts from the leaves of Flueggea virosa and Newbouldia laevis.is the goal of this study. All extracts exhibited notable antioxidant activity. Amon
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Efoé, Sossou, Domedjui Komi L, Novidzro Kosi M, Ocansey Bright, Dorkenoo Ameyo M, and Gbogbo Koffi A. "Antifungal Properties and Phytochemical Composition of Ficus platyphylla Stem Bark and Leaves Extracts." Journal of International Research in Medical and Pharmaceutical Sciences 20, no. 2 (2025): 13–23. https://doi.org/10.56557/jirmeps/2025/v20i29343.

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Introduction: Ficus platyphylla is a plant species used in traditional medicine to treat microbial diseases. The leaves and stem bark are the most widely used parts of this plant. Stady Design: It was a prospective study. Objective: The aim of the present study was to investigate alternative plant-based treatments for mycoses in Togo. Methods: Hydroethanolic and aqueous extracts of the bark and leaves of F. platyphylla were tested in a comparative approach on five reference strains (Candida albicans ATCC90028, Candida krusei ATCC6258, Candida parapsilosis ATCC 22019, Trichophyton mentagrophyte
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Moungang, Luciane Marlyse, Brigitte Ndemangou, Roland Ndifor Ache, et al. "Phytochemical Screening and Potential Antibacterial, Antifungi and Antioxidative Activities of the Leaves Extracts of Piperomia pellucida (Piperaceae)." Journal of Applied Life Sciences International 26, no. 5 (2023): 35–46. http://dx.doi.org/10.9734/jalsi/2023/v26i5617.

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The hexane, ethanolic, hydroethanolic and aqueous leaves extracts of Piperomia pellucida were evaluated in vitro for their antimicrobial activity against five gram negative bacilli (Klebsiella pneumoniae CHUY, Escherichia coli ATCC 35218, Pseudomonas aeruginosa ATCC 27853, Salmonella typhi CHUY and Salmonella enterica CHUY), two cocci gram positive (Staphylococcus aureus ATCC 25923 and Enterococcus faecalis ATCC 5199) and two fungi (Candida albicans CHUY and Candida albicans 20231) using microdilution techniques. The extracts were also assayed for their antioxidant properties by DPPH and FRAP
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Sibri, Jean François, Joël Akakpo-Akue, Obou Constantin Okou, and Tatiana Kangah Mireille Kple. "Evaluation of the Antioxidant Activity of Aqueous and Hydro-Ethanolic Extracts of Ficus capensis, Newbouldia laevis and Carpolobia lutea." Asian Journal of Research in Biochemistry 13, no. 4 (2023): 9–15. http://dx.doi.org/10.9734/ajrb/2023/v13i4267.

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Scientific interest in the search for natural antioxidants (secondary metabolites) in medicinal plants has increased considerably in recent years, as free radicals are at the root of many diseases. The aim of this study was to evaluate the antioxidant activity of aqueous and hydroethanol extracts from the leaves of a basic plant product consisting of equal quantities of Ficus capensis, Newbouldia laevis and Carpolobia lutea. Quantitative determination of antioxidant activity was based on the flavonoid content of the base plant product. It was assessed by DPPH (2, 2-diphenyl-l-picrylhydrazyl) r
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de Sousa, João Paulo B., Ana Paula S. Brancalion, Milton G. Júnior, and Jairo K. Bastos. "A Validated Chromatographic Method for the Determination of Flavonoids in Copaifera langsdorffii by HPLC." Natural Product Communications 7, no. 1 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700110.

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Hydroethanolic extracts of C. langsdorffii leaves have therapeutic potential. This work reports a validated chromatographic method for the quantification of polar compounds in the hydroethanolic extract of C. langsdorffii leaves. A reliable HPLC method was developed using two monolithic columns linked in series (100 × 4.6 mm – C18), with nonlinear gradient elution, and UV detection set at 257 nm. A procedure for the extraction of flavonols was also developed, which involved the use of 70% aqueous ethanol and the addition of benzophenone as the internal standard. The developed method led to a g
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Aabideen, Zain Ul, Muhammad Waseem Mumtaz, Muhammad Tayyab Akhtar, et al. "Cassia fistula Leaves; UHPLC-QTOF-MS/MS Based Metabolite Profiling and Molecular Docking Insights to Explore Bioactives Role towards Inhibition of Pancreatic Lipase." Plants 10, no. 7 (2021): 1334. http://dx.doi.org/10.3390/plants10071334.

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The present work was aimed at investigating hydroethanolic leaf extracts of Cassia fistula for their antioxidant and pancreatic lipase (PL) enzyme inhibitory properties. The most active extract was selected to profile the phytoconstituents by UHPLC-QTOF-MS/MS technique. Among the tested extracts, the 80% hydroethanolic extract exhibited the maximum levels of total phenolic and flavonoid contents (TPC and TFC) with a contribution of 201.3 ± 2.6 mg of gallic acid equivalent per gram of extract (GAE/g extract), and 116.3 ± 2.4 mg of rutin equivalent per gram of extract (RE/g extract), respectivel
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Mahamadou N. H, BALLO, Youl Estelle N.H, Traore Karim, et al. "study of antiradical activity, phospholipase A and 15-lipoxygenase inhibitory activity of eight malian medicinal plants used by traditional healers to treat inflammatory diseases." Indian Journal of Pharmacy and Pharmacology 9, no. 3 (2022): 174–79. http://dx.doi.org/10.18231/j.ijpp.2022.031.

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Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-inflammatory drugs. In this study, the objective was to evaluate the antiradical activity of the extracts and their ability to inhibit phospholipase A and 15-lipoxygenase activity. The hydroethanolic extract of revealed the strongest reducing power with an IC of 7.29 ± 0.61 µg/mL. The three most active extracts on PLA were hydroethanolic extracts of (IC of 21.43 ± 0.66 μg/mL), (IC of 23.72 ± 0.71 µg/mL), (IC of 24.49 ± 0.39 µg/mL). The best inhibitory activity on 15-lipoxigenase was obtained wi
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El Khomsi, Mostafa, Mohammed Kara, Anouar Hmamou, et al. "In Vitro Studies on the Antimicrobial and Antioxidant Activities of Total Polyphenol Content of Cynara humilis from Moulay Yacoub Area (Morocco)." Plants 11, no. 9 (2022): 1200. http://dx.doi.org/10.3390/plants11091200.

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In Morocco, Cynara humilis L. is used in traditional medicine. The objective of this research was to research the antioxidant and antimicrobial properties of hydroethanolic extracts from the C. humilis plant’s leaves and roots. The content of polyphenols and flavonoids was evaluated using Folin–Ciocalteu’s and aluminum chloride assays. Two techniques were used to evaluate antioxidant properties: antioxidant capacity in total (TAC) and 2,2-diphenyl-1-picrylhdrazyl (DPPH). In antimicrobial assays, five pathogenic microbial strains were studied including two Escherichia coli, one coagulase-negati
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Fankibe, Nakpane, Yendubé T. Kantati, Kossi Metowogo, et al. "Antioxidant, Anti-Inflammatory and Wound Healing Activities of Cochlospermum planchonii Hook. F." Journal of Drug Delivery and Therapeutics 12, no. 2-S (2022): 63–71. http://dx.doi.org/10.22270/jddt.v12i2-s.5267.

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Objective: The medicinal plant Cochlospermum planchonii Hook.f. is used in the management of various ailments in Togolese pharmacopoeia. In this study, we aimed to evaluate the antioxidant and anti-inflammatory activities of roots and leaves of C. planchonii, and burn wound healing activity of its leaf hydroethanolic extracts in rodents.&#x0D; Materials and Methods: Antioxidant activities were assessed using Phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) test and the reducing power assay. Visceral pain model, formaldehyde-induced paw edema and vascular permeability test were per
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Fankibe, Nakpane, Yendubé T. Kantati, Kossi Metowogo, et al. "Antioxidant, Anti-Inflammatory and Wound Healing Activities of Cochlospermum planchonii Hook. F." Journal of Drug Delivery and Therapeutics 12, no. 2-S (2022): 63–71. http://dx.doi.org/10.22270/jddt.v12i2-s.5267.

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Objective: The medicinal plant Cochlospermum planchonii Hook.f. is used in the management of various ailments in Togolese pharmacopoeia. In this study, we aimed to evaluate the antioxidant and anti-inflammatory activities of roots and leaves of C. planchonii, and burn wound healing activity of its leaf hydroethanolic extracts in rodents.&#x0D; Materials and Methods: Antioxidant activities were assessed using Phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) test and the reducing power assay. Visceral pain model, formaldehyde-induced paw edema and vascular permeability test were per
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Fankibe, Nakpane, Yendubé T. Kantati, Kossi Metowogo, et al. "Antioxidant, Anti-Inflammatory and Wound Healing Activities of Cochlospermum planchonii Hook. F." Journal of Drug Delivery and Therapeutics 12, no. 2-S (2022): 63–71. http://dx.doi.org/10.22270/jddt.v12i2-s.5267.

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Objective: The medicinal plant Cochlospermum planchonii Hook.f. is used in the management of various ailments in Togolese pharmacopoeia. In this study, we aimed to evaluate the antioxidant and anti-inflammatory activities of roots and leaves of C. planchonii, and burn wound healing activity of its leaf hydroethanolic extracts in rodents.&#x0D; Materials and Methods: Antioxidant activities were assessed using Phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) test and the reducing power assay. Visceral pain model, formaldehyde-induced paw edema and vascular permeability test were per
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Zouhri, Aziz, Toufik Bouddine, Naoual El Menyiy, et al. "Chemical composition and potential antioxidant, anti-inflammatory, and analgesic efficacy of Cistus albidus L." Acta Pharmaceutica 74, no. 1 (2024): 81–99. http://dx.doi.org/10.2478/acph-2024-0002.

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Abstract This study aims to assess the chemical composition of the aqueous extract of Cistus albidus L. leaves, as well as the potential of aqueous and hydroethanol extracts of the leaves and seeds as analgesic, anti--inflammatory, and antioxidant agents. The contents of phenolics and inorganic constituents were determined in C. albidus seeds and leaves; antioxidant capacity was assessed by 3 complementary and diverse tests. The carrageenan-induced paw edema technique was used to investigate the anti-inflammatory effect in vivo, and albumin denaturation to evaluate the anti-inflammatory effect
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Malú, Quintino, Katelene Lima, Maryam Malmir, et al. "Contribution to the Preclinical Safety Assessment of Lannea velutina and Sorindeia juglandifolia Leaves." Plants 12, no. 1 (2022): 130. http://dx.doi.org/10.3390/plants12010130.

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Dried leaves of Lannea velutina A. Rich. and Sorindeia juglandifolia (A. Rich.) Planch. ex Oliv. (family Anacardiaceae) are used in African traditional medicine. Although these medicinal plants have widespread use in the treatment of inflammatory diseases, there is no scientific data concerning their preclinical or clinical safety. This work aimed to investigate the phytochemical properties of the leaves of both species using HPLC-UV/DAD, as well as the in vivo oral repeated-dose toxicity of 70% hydroethanolic leaf extract of S. juglandifolia and the in vitro genotoxicity of 70% hydroethanolic
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Luquis, Fernando, Andréia Aparecida Oliveira Silva, Nilsa Sumie Yamashita Wadt, Edgar Matias Bach Hi, Ana Maria Cristina CRPF Martins, and Erna Elisabeth Bach. "Arctium lappa L.: Chemical composition, antioxidants, phytochemical compounds and use for healing activity." South Florida Journal of Development 2, no. 2 (2021): 2063–71. http://dx.doi.org/10.46932/sfjdv2n2-073.

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Arctium lappa L, popularly known as burdock, is a medicinal plant with wide application in chinese folk medicine. The objective of the present work was to proceed hydroethanolic extraction of the leaves, to analyze the chemical compounds as proteins, phenols, antioxidants, phytochemical and its skin healing potential in exposed cutaneous lesions in rats treated with gel containing the extract. For preparation the extract, fresh leaves of the burdock plant were obtained from Sitio Wadt located in Valinhos, SP and dried. 50g of dry leaves was subjected to percolation. Extract was tested to quant
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Feudjio, Huguette Bocanestine Laure, Marie Stéphanie Chekem Goka, Josias Djenguemtar, et al. "Antityphoid and Antioxidant Activities of Leaf Extracts of Dracaena deisteliana Eng. (Dracaenaceae)." International Journal of TROPICAL DISEASE & Health 44, no. 22 (2023): 1–18. http://dx.doi.org/10.9734/ijtdh/2023/v44i221494.

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Salmonellosis is a major public health problem in developing countries where it is endemic. The genus Salmonella express the oxyR gene that codes for several proteins that allow them to resist free radicals. To investigate the antioxidant activity in vitro (aqueous and hydroethanolic extracts in vivo (of the 55% hydroethanolic extract)) of Dracaena deisteliana leaves in albino’s rats of Wistar strain previously infected with the Salmonella Typhi ATCC 6539 strain. The in vitro antioxidant activity of these extracts was determined by studying their anti-radical power with DPPH●, then their iron-
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Celaya, Liliana, Carmen Viturro, and Luís R. Silva. "Acantholippia salsoloides: Phytochemical Composition and Biological Potential of a Thujonic Population." Natural Product Communications 14, no. 6 (2019): 1934578X1985854. http://dx.doi.org/10.1177/1934578x19858542.

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Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine. A. salsoloides attributes its common name “rica-rica” to the fresh and sweet fragrance of the plant. In this work, 2 different polar extracts and the essential oil of a selected rica-rica population were studied. The phenolic composition was analyzed by high-performance liquid chromatography diode array detector; the essential oil profile was determined by
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DERMANE ET AL., Affo. "Antioxidant and antimicrobial activities of Momordica charantia L. leaves." International Journal of Pharmaceutical, Physico-chemical and Nutritional Analysis 1, no. 2 (2023): 3–8. http://dx.doi.org/10.61585/ucad-ijppna-v1i202.

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Momordica charantia L. is used as a broad-spectrum antibacterial agent to fight infections. This work aimed at evaluating antioxidant and antimicrobial activities of hydroethanolic extract of Momordica charantia leaves. The extract was obtained by maceration of crude leaf powder (hydroethanolic 30:70). The phytochemical screening was focused on the detection of major chemical groups. The total flavonoid contents were studied using the aluminum chloride colorimetric method. The antioxidant capacity was carried out by the phosphomolybdate reduction method and by FRAP method. The antimicrobial ac
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Ouattara, Abou, Youssouf Traore, Gboko Abiba Ouattara, Gnidian Konate, Karamoko Ouattara, and Adama Coulibaly. "Antioxidant and anti-gastroenteritis activities of Funtumia elastica (Apocynaceae) and Caesalpinia bonduc (Caeasalpiniaceae)." International Journal of Biological and Chemical Sciences 14, no. 1 (2020): 170–80. http://dx.doi.org/10.4314/ijbcs.v14i1.14.

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Oxidative stress and infectious diseases are health problems on a global scale. The aim of this study was to evaluate the antioxidant and anti-gastroenteritis activities of hydroethanolic extracts of leaves of Funtumia elastica and Caesalpinia bonduc. After obtaining the hydroethanolic extracts, the phytochemical tests were carried out. The antioxidant activity was evaluated by different assays using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and lipid peroxidation inhibition (FTC and TBARS methods). The agar well diffusion method was used to determine the antibacterial activity to the plant extract
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Itakpe, Josephine Iruolagbe, Beatrice E. Imananaghe Amene, Robinson Ohanador, et al. "Hydroethanolic Leaves Extract of Bryophyllum pinnatum Modulates Kim-1 Expression in Methyl Mercury Induced Kidney Damage." Scholars Journal of Applied Medical Sciences 13, no. 04 (2025): 833–37. https://doi.org/10.36347/sjams.2025.v13i04.001.

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Bryophyllum pinnatum is a perennial herb native to Madagascar, it is used locally in the treatment of several conditions in folklore medicine. The aim of this study is to investigate the efficacy of Bryophyllum pinnatum leaves aqueous extract in Methyl mercury-induced kidney damage in wistar albino rat model. Methyl mercury, an environmental toxicant has the potential to cause kidney damage when exposed in a large quantity. Twenty five adult male wistar albino rats were given 2 mg/kg of methyl mercury to induce kidney damage. Group B received 2mg/kg of methyl mercury without treatment, animals
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Zabbey, VZ, OM Adienbo, SO Ojeka, and DV Dapper. "PHYTOCHEMICAL SCREENING AND GC–MS ANALYSIS OF BIOACTIVE COMPOUNDS PRESENT IN HYDROETHANOLIC LEAF EXTRACT OF SOLANUM AETHIOPICUM (L)." GPH-International Journal of Biological & Medicine Science 05, no. 01 (2022): 01–09. https://doi.org/10.5281/zenodo.6849713.

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<em>Solanum aethiopicum</em> is a popular traditional vegetable cultivated widely in tropical Africa. It is a species of garden egg grown mostly for the nutritional and medicinal values of its leaves and fruits. This research was carried out to investigate the phytochemicals and GC-MS analysis of the hydroethanolic leaf extract of <em>Solanum aethiopicum</em>. Fresh, healthy, and young leaves of the plant were collected from a farm in Omuokiri in Aluu, Port Harcourt, Rivers State, Nigeria. These collected leaves were air-dried and grounded into a powdered form and subjected to selective sequen
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Ashim, Aizhan, Lama Ismaiel, Benedetta Fanesi, et al. "Food-Grade Polar Extracts from Sea Fennel (Crithmum maritimum L.) By-Products: Unlocking Potential for the Food Industry." Foods 14, no. 13 (2025): 2304. https://doi.org/10.3390/foods14132304.

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Crithmum maritimum L. is a halophyte with antioxidant and antimicrobial potential for the food industry. Pruning generates a by-product composed of woody stems, old leaves, and flowers. To valorize this underutilized and largely unexplored biomass, food-grade polar extraction (hydroethanolic vs. aqueous) was applied. The extracts were characterized for their bioactive compounds (polyphenols, tocopherols, carotenoids, total phenols (TPC) and total flavonoids (TFC)). Further, the extracts were assessed for their in vitro antioxidant activity (ABTS, DPPH, FRAP, and β-carotene bleaching) and antim
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Kumari, Anjana, Vinit Prakash, Dinesh Gupta, et al. "Identification and evaluation of antimicrobial and anti-arthritis activities of hydroethanolic extract of Rubus ellipticus leaves." Narra J 3, no. 3 (2023): e152. https://doi.org/10.52225/narra.v3i3.152.

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Rubus ellipticus is a native plant to India's tropical and subtropical regions and has been used as a traditional medicinal. The aim of the study was to identify and evaluate the antimicrobial and anti-arthritis activities of hydroethanolic extract of R. ellipticus leaves (HEERE). The leaves were collected from the Narkanda Valley, India and were shade-dried and finely ground to produce the powder. The hydroethanolic extract was utilized for phytochemical analysis to determine the existence of carbohydrate, phenolic, terpenoid, flavonoid, saponin, glycoside, tannin, protein, and alkaloid. The
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Mihai, Sebastian, Denisa Dumitrescu, Madalina Ana Raducanu, Iuliana Stoicescu, and Victoria Badea. "Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract." Revista de Chimie 70, no. 1 (2019): 23–26. http://dx.doi.org/10.37358/rc.19.1.6843.

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The scope of this work is a phytochemical analysis and antioxidant activity assay of a Sempervivum ruthenicum Koch hydroethanolic extract. The hydroethanolic extract was prepared from the dried leaves of the plant by maceration in a water and methanol mixture (50:50 v/v). The total phenolic content of the extract was calculated to be 3.0501�0.0272 mg/mL and the total flavonoid content was determined in a concentration of 3.113�0.0394 mg/mL. The HPLC-DAD analysis revealed phenolic acids and flavonoids, which were quantified. The most prevalent phenolic acids in the extracts were gallic and ella
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Azevedo, Sthéfanny Caroline Mendes, Bruno Sampaio Amorim, Rogéria Cristina Zauli, et al. "The Antileishmanial, Antioxidant and Cytotoxic Potential of Cecropia concolor Willd (Urticaceae), an Amazonian Species." Processes 12, no. 10 (2024): 2237. http://dx.doi.org/10.3390/pr12102237.

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Cecropia sp. (Urticaceae) are commonly used in traditional medicine in South American countries for the treatment of different diseases. To date, the species Cecropia concolor Willd, of Amazonian occurrence, has not been investigated for its pharmacological potential. In this study, we described the chemical profile and the antileishmanial, antioxidant and cytotoxic activities of extracts of the leaves of C. concolor. The ethanolic extract and its partition phases (hexane, ethyl acetate and hydroethanolic) were analyzed for their chemical classes and phenolic content. Antileishmanial activity
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Ouadja, Batcha, Gnatoulma Katawa, Gerard A. Toudji, et al. "Anti-inflammatory, antibacterial and antioxidant activities of Chenopodium ambrosioides L. (Chenopodiaceae) extracts." Journal of Applied Biosciences 162 (June 30, 2021): 16764–94. http://dx.doi.org/10.35759/jabs.162.7.

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Objective: Chenopodium ambrosioides is an aromatic plant widely used in the Togolese traditional medicine. However, little is known about its pharmacological properties. The present study aimed to investigate the anti-inflammatory, antibacterial and antioxidant activities of its extracts. Methodology and results: Thus, an ethnopharmacological survey was undertaken in Kara town in the northern part of Togo to assess the main uses in the traditional medicine and Gas Chromatography coupled with Mass Spectral Analysis (GC-MS) was used to identify several compounds in the extracts. Antioxidant acti
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Michalak, Monika, Małgorzata Stryjecka, Paulina Żarnowiec, Martyna Zagórska-Dziok, and Anna Kiełtyka-Dadasiewicz. "Chemical Composition of Extracts from Various Parts of Feverfew (Tanacetum parthenium L.) and Their Antioxidant, Protective, and Antimicrobial Activities." International Journal of Molecular Sciences 25, no. 22 (2024): 12179. http://dx.doi.org/10.3390/ijms252212179.

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Tanacetum parthenium is a medicinal plant from the Asteraceae family that can be applied externally in the case of various skin diseases. The aim of the study was to perform a phytochemical analysis of hydroethanolic extracts from the aerial parts (herb), flower heads, and leaves of feverfew and to assess their biological properties. Hydrodistilled oils were analyzed using GC-MS. The chemical composition of the extracts was estimated using spectrophotometry and the HPLC method. Moreover, the extracts were evaluated to determine their antioxidant potential using DPPH and FRAP and measuring the
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Puthallath, Rejeesh Edavan, Sridevi Kotekar, S. N. Rao, Megha Rani Narayana, and Roopa P. Nayak. "Effect on anxiety of Coriandrum sativum leaf hydroethanolic extract oil and aqueous fraction in swiss albino mice." International Journal of Basic & Clinical Pharmacology 9, no. 7 (2020): 1032. http://dx.doi.org/10.18203/2319-2003.ijbcp20202936.

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Background: Anxiety is a protective reflex and the most common disorder. This study was done to evaluate the effect of anxiolytic property of oil and aqueous fractions isolated from hydroethanolic extracts of Coriandrum sativum leaf by novel freezing technique with swiss albino mice.Methods: Hydroethanolic extract of Coriandrum sativum leaves was prepared. Oil and aqueous part were separated with freezing technique. Animals were divided into six groups. Ist group served as control and 1% DMSO was administered orally. IInd to Vth group were administered with Coriandrum sativum oil fraction and
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Gupta, Vijeta, and Vijender Singh. "ANTIPSYCHOTIC ACTIVITY ON HYDROETHANOLIC EXTRACT OF LEAVES OF CITRUS LIMON LINN." International Journal of Research in Ayurveda & Pharmacy 8, no. 3 (2017): 217–19. http://dx.doi.org/10.7897/2277-4343.083203.

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Casagrande, Junior Cesar, Luis Fernando Benitez Macorini, Katia Avila Antunes, et al. "Antioxidant and Cytotoxic Activity of Hydroethanolic Extract from Jacaranda decurrens Leaves." PLoS ONE 9, no. 11 (2014): e112748. http://dx.doi.org/10.1371/journal.pone.0112748.

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Lopes, Rafael Henrique Oliveira, Luis Fernando Benitez Macorini, Katia Ávila Antunes, et al. "Antioxidant and Hypolipidemic Activity of the Hydroethanolic Extract ofCuratella americanaL. Leaves." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/9681425.

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High levels of reactive oxygen species in the body and hyperlipidemia are key factors for the development of cardiovascular diseases such as atherosclerosis. The present study investigated the antioxidant and hypolipidemic activity of hydroethanolic extract ofCuratella americanaL. leaves (ExC). The antioxidant activity of ExC was assessed by 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH) scavenging capacity and protection against hemolysis induced by 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH), followed by quantification of malondialdehyde (MDA). Wistar rats with hyperlipidemia ind
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Youssef, Seria, Luisa Custódio, Maria João Rodrigues, et al. "Harnessing the Bioactive Potential of Limonium spathulatum (Desf.) Kuntze: Insights into Enzyme Inhibition and Phytochemical Profile." Plants 12, no. 19 (2023): 3391. http://dx.doi.org/10.3390/plants12193391.

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This study assessed the halophyte species Limonium spathulatum (Desf.) as a possible source of natural ingredients with the capacity to inhibit enzymes related to relevant human health disorders and food browning. Extracts using food-grade solvents such as water and ethanol were prepared by maceration from dried L. spathulatum leaves. They were evaluated for in vitro inhibition activity of enzymes such as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), α-glucosidase, tyrosinase and lipase, related to Alzheimer’s disease, type-2-diabetes mellitus, skin hyperpigmentation, and obesi
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Emmanuel Orou Doro Bakrou, Yaya Alain Koudoro, Sophie Reine Gbedossou Bogninou, et al. "Phytochemical screening and evaluation of antiradical and antimicrobial activities of Annona senegalensis and Detarium microcarpum leaves used in Benin to treat urinary infections." GSC Biological and Pharmaceutical Sciences 29, no. 1 (2024): 214–23. http://dx.doi.org/10.30574/gscbps.2024.29.1.0387.

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The challenge of resistance to synthetic antimicrobials necessitates new alternative solutions. Medicinal plants are rich in active compounds with various medicinal properties that can be used in treatment of urinary infections. This work aims to highlight the value of Annona senegalensis and Detarium microcarpum by evaluating phytochemical and antimicrobial potentials of their leaf extracts. Qualitative and quantitative analyses were carried out using color and precipitation reactions and spectrophotometric assays. The antiradical activity was evaluated using the DPPH test, and the antimicrob
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