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1

Nguyen, Hien Van, Dung Thi Ngo, Dat Vinh Lieu, and Tuan Thanh Tran. "Combination of Anterior and Posterior Vaginal Mesh Implants and Delorme Procedure in a 94-year-old female with Pelvic Organ Prolapse." Nigerian Postgraduate Medical Journal 31, no. 2 (2024): 170–72. http://dx.doi.org/10.4103/npmj.npmj_32_24.

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Pelvic organ prolapse refers to the descent of pelvic floor organs resulting from the weakening of pelvic muscles, fascia and connective tissue. The overall prevalence of pelvic organ prolapse is approximately 41%, including bladder prolapse (25%–34%), uterine prolapse (4%–14%) and rectal prolapse (13%–19%). Various methods are currently employed to repair damaged structures and improve patient symptoms, consequently enhancing their quality of life. This report focuses on a 94-year-old female diagnosed with pelvic organ prolapse, specifically Grade 3 bladder prolapse, Grade 3 uterine prolapse
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Premaratne, Sobath, Jonathan Hopkins, Martin Duddy, et al. "Abdominal Aortic Aneurysm Repair in Renal and Liver Transplant Recipients." Vascular and Endovascular Surgery 54, no. 1 (2019): 51–57. http://dx.doi.org/10.1177/1538574419880673.

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Background: Abdominal aortic aneurysm (AAA) repair in patients with organ transplant remains a challenge. We looked at AAA repair in patients with organ transplants at our tertiary liver and kidney transplant unit. Methods: A retrospective analysis of a prospectively maintained database was undertaken from January 2008 to July 2018. We looked at patient demographics, type of repair, and technical success including reinterventions, perioperative transplant organ function, and 30-day and 1-year survival rate. Eight of 662 patients who underwent AAA repair had a solid organ transplant. Of these,
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Ofori, A. A., and H. S. Opare-Addo. "Surgical Management of Pelvic Organ Prolapse." Postgraduate Medical Journal of Ghana 10, no. 1 (2022): 60–65. http://dx.doi.org/10.60014/pmjg.v10i1.253.

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Pelvic organ prolapse (POP) is a common condition that affects the quality of life of affected women. A prevalence of 12% has been reported in Ghana with the condition affecting mainly the emotional wellbeing, sexual life and women’s relationship with their partners. This review discusses the adequacy of the available surgical options for managing POP and provide our expert opinion and recommendations based on our experience. Surgical management of POP is undertaken through 2 main approaches i.e., obliterative and reconstructive. Obliterative procedures should only be considered for women who
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Bussolati, Benedetta. "Stem cells for organ repair." Organogenesis 7, no. 2 (2011): 95. http://dx.doi.org/10.4161/org.7.2.16605.

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Miller, Gerald E. "Sensory Organ Replacement and Repair." Synthesis Lectures on Biomedical Engineering 1, no. 1 (2006): 1–65. http://dx.doi.org/10.2200/s00022ed1v01y200604bme003.

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Jackson, Kevin S., Kari Inoue, David A. Davis, Tyvette S. Hilliard, and Joanna E. Burdette. "Three-Dimensional Ovarian Organ Culture as a Tool to Study Normal Ovarian Surface Epithelial Wound Repair." Endocrinology 150, no. 8 (2009): 3921–26. http://dx.doi.org/10.1210/en.2008-1674.

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Ovarian cancers are primarily derived from a single layer of epithelial cells surrounding the ovary, the ovarian surface epithelium (OSE). Ovarian surface proliferation is associated with ovulation and has been suggested to play a role in ovarian surface transformation and cancer progression. Aspects of ovarian surface repair after ovulation include proliferation, migration, and surface regeneration. To study ovarian surface repair, an organ culture system was developed that supports the proliferation, encapsulation, and repair of an artificially wounded surface. Wounded mouse ovaries embedded
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Lallemant, Marine, Yasmine Clermont-Hama, Géraldine Giraudet, et al. "Long-Term Outcomes after Pelvic Organ Prolapse Repair in Young Women." Journal of Clinical Medicine 11, no. 20 (2022): 6112. http://dx.doi.org/10.3390/jcm11206112.

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The aim of the study was to describe the long-term outcomes of Pelvis Organ Prolapse (POP) repair in women under 40 years old. A retrospective chart review of all POP repairs performed in women ≤40 years old between January 1997 and December 2015 in the Gynecologic Surgery Department of Lille University Hospital was performed. Inclusion criteria were all women ≤40 years old who underwent a POP repair with a stage ≥2 POP according to the Baden and Walker classification. The study population was separated into three groups: a sacrohysteropexy group, a vaginal native tissue repair (NTR) group, an
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Burdick, Jason A. "Injectable gels for tissue/organ repair." Biomedical Materials 7, no. 2 (2012): 020201. http://dx.doi.org/10.1088/1748-6041/7/2/020201.

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Baddour, Joëlle A., Konstantinos Sousounis, and Panagiotis A. Tsonis. "Organ repair and regeneration: An overview." Birth Defects Research Part C: Embryo Today: Reviews 96, no. 1 (2012): 1–29. http://dx.doi.org/10.1002/bdrc.21006.

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ROGERS, ROBERT M., and CHARLES E. MILLER. "Pelvic Organ Prolapse Repair With Prolift." Ob.Gyn. News 44, no. 3 (2009): 16–17. https://doi.org/10.1016/s0029-7437(09)70038-2.

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Fairclough, Emily, Julia Segar, Jenny Myers, Anthony Smith, and Fiona Reid. "Surgical technique used in the UK for native tissue anterior pelvic organ prolapse repair (VaST)." International Urogynecology Journal 31, no. 8 (2019): 1519–25. http://dx.doi.org/10.1007/s00192-019-04103-8.

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Abstract Introduction The PROSPECT study found that outcomes for native tissue and mesh prolapse repairs are similar but mesh repairs have a 10% risk of exposure. The current UK surgical mesh pause has led to renewed interest in native tissue surgery. Previous studies of native tissue anterior repair surgical techniques have been limited by the questionnaire study design. The objective of this study was to describe and categorise native tissue anterior repair surgical techniques. Methods This prospective qualitative study used a purposive sampling strategy to recruit surgeons. Data were collec
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Dion, Vincent. "Tissue specificity in DNA repair: lessons from trinucleotide repeat instability." Trends In Genetics : Tig 30, no. 6 (2014): 220–29. https://doi.org/10.1016/j.tig.2014.04.005.

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DNA must constantly be repaired to maintain genome stability. Although it is clear that DNA repair reactions depend on cell type and developmental stage, we know surprisingly little about the mechanisms that underlie this tissue specificity. This is due, in part, to the lack of adequate study systems. This review discusses recent progress toward understanding the mechanism leading to varying rates of instability at expanded trinucleotide repeats (TNRs) in different tissues. Although they are not DNA lesions, TNRs are hotspots for genome instability because normal DNA repair activities cause ch
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Sawant, Aditi, Anuja Bhalerao, and Kritika Bhalerao. "Effect of traditional versus site specific anterior repair in reduction of urinary symptoms in women with pelvic organ prolapse." Indian Journal of Obstetrics and Gynecology Research 8, no. 4 (2021): 507–12. http://dx.doi.org/10.18231/j.ijogr.2021.105.

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The present study was undertaken to evaluate effect of traditional anterior repair versus site specific anterior repair in reduction of urinary symptoms in women with Pelvic organ Prolapse. During the study period of 2 years 140 women belonging to reproductive, peri-menopausal and postmenopausal age groups were included in the study. Employing past literature, the sample size calculated was 140. All women were assessed pre-operatively by the assessment method – Pelvic organ prolapse quantification (POP-Q) system. 70 women belonging to Group A were treated according to vaginal hysterectomy with
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Kalkan, U., T. Yoldemir, E. S. Ozyurek, and A. Daniilidis. "Native tissue repair versus mesh repair in pelvic organ prolapse surgery." Climacteric 20, no. 6 (2017): 510–17. http://dx.doi.org/10.1080/13697137.2017.1366978.

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ORAZOV, M. R., V. E. RADZINSKIY, and F. F. MINNULLINA. "Mechanisms of pelvic organ prolapse recurrence." Practical medicine 22, no. 6 (2024): 23–28. https://doi.org/10.32000/2072-1757-2024-6-23-28.

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The long-term results of surgical treatment of pelvic organ prolapse (POP) do satisfy neither doctors nor patients: after surgery successful in short term, the risk of recurrence reaches 50%, and the rate of repeated interventions is 30%. Currently, practical medicine is in urgent need of strategies aimed at improving postoperative repair of pelvic floor soft tissues in order to prevent recurrence of genital prolapse. The purpose — to search and analyze the evidence on the mechanisms of pelvic floor soft tissue repair disorders after POP surgical treatment as a key aspect of genital prolapse r
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Cohen, Erez, Jessica K. Sawyer, Nora G. Peterson, Julian A. T. Dow, and Donald T. Fox. "Physiology, Development, and Disease Modeling in the Drosophila Excretory System." Genetics 214, no. 2 (2020): 235–64. http://dx.doi.org/10.1534/genetics.119.302289.

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The insect excretory system contains two organ systems acting in concert: the Malpighian tubules and the hindgut perform essential roles in excretion and ionic and osmotic homeostasis. For over 350 years, these two organs have fascinated biologists as a model of organ structure and function. As part of a recent surge in interest, research on the Malpighian tubules and hindgut of Drosophila have uncovered important paradigms of organ physiology and development. Further, many human disease processes can be modeled in these organs. Here, focusing on discoveries in the past 10 years, we provide an
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Whitson, BryanA, and SylvesterM Black. "Regional organ Assessment and Repair Centers (ARCs)." Ibnosina Journal of Medicine and Biomedical Sciences 5, no. 5 (2013): 243. http://dx.doi.org/10.4103/1947-489x.210552.

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Turner, Lindsay C., Halina M. Zyczynski, and Jonathan P. Shepherd. "Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair." Obstetrics & Gynecology 133, no. 3 (2019): 492–502. http://dx.doi.org/10.1097/aog.0000000000003102.

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Keshavjee, Shaf. "Human organ repair centers: Fact or fiction?" JTCVS Open 3 (September 2020): 164–68. http://dx.doi.org/10.1016/j.xjon.2020.05.001.

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Cronjé, H. S., and J. A. A. de Beer. "Culdocele repair in female pelvic organ prolapse." International Journal of Gynecology & Obstetrics 100, no. 3 (2007): 262–66. http://dx.doi.org/10.1016/j.ijgo.2007.08.016.

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Osborn, David J., W. Stuart Reynolds, and Roger Dmochowski. "Vaginal approaches to pelvic organ prolapse repair." Current Opinion in Urology 23, no. 4 (2013): 299–305. http://dx.doi.org/10.1097/mou.0b013e3283619e1a.

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Jiang, Guojing, Bin Yan, Yu Wang, and Qingliang Ma. "Transvaginal mesh repair for pelvic organ prolapse." Journal of Obstetrics and Gynaecology Research 40, no. 4 (2014): 1046–50. http://dx.doi.org/10.1111/jog.12279.

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Rangwala, Fatima, Alessia Omenetti, and Anna Mae Diehl. "Cancer Stem Cells: Repair Gone Awry?" Journal of Oncology 2011 (2011): 1–11. http://dx.doi.org/10.1155/2011/465343.

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Because cell turnover occurs in all adult organs, stem/progenitor cells within the stem-cell niche of each tissue must be appropriately mobilized and differentiated to maintain normal organ structure and function. Tissue injury increases the demands on this process, and thus may unmask defective regulation of pathways, such as Hedgehog (Hh), that modulate progenitor cell fate. Hh pathway dysregulation has been demonstrated in many types of cancer, including pancreatic and liver cancers, in which defective Hh signaling has been linked to outgrowth of Hh-responsive cancer stem-initiating cells a
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Li, Ying, Shu Jiang Zhang, and Huo Yan Wu. "Progress in Cartilage Tissue Engineering with Nanostructured Extracellular Matrix." Advanced Materials Research 643 (January 2013): 144–48. http://dx.doi.org/10.4028/www.scientific.net/amr.643.144.

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Tissue defects and organ failure have seriously threatened the health and life of human beings and are challenges in modern medicine we have been trying to overcome. They are often treated with tissue and organ transplantation. Although autologous tissue transplantation is not bothered by immune rejection, it could cause defects of the donor site and create new pains. Therefore, scientists are striving to explore more ideal principles and methods while working hard to improve the existing treatments as most as possible. The rise and development of tissue engineering will be possible to provide
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Aloba, Christianah Oreoluwa. "Organ-on-a-Chip in Regenerative Medicine: Advancing Tissue Repair and Personalized Therapies." International Journal of Research Publication and Reviews 6, no. 1 (2025): 2427–46. https://doi.org/10.55248/gengpi.6.0125.0438.

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aziz, dalya. "MESH REPAIR FOR SACROCOCCYGEAL HERNIA: A CASE REPORT." Journal of Sulaimani Medical College 14, no. 1 (2024): 187–90. https://doi.org/10.17656/jsmc.10464.

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INTRODUCTION A hernia will happen when the body’s parts or internal tissues pass through the muscle’s weakness or the wall of the surrounding tissue. Hernia could be congenital or acquired. Most cases of hernia occur in the chest and posterior part of the pelvis. They are usually asymptomatic or have few symptoms, and depending on the organ involved, mass or swelling can be the most common symptom (1). A sacrococcygeal hernia is located between the rectum and the end part of the presacral spine (2). In general, the development of lesions such as tumors, cysts, and hernias in the presacral regi
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Majumder, Sreyosi. "The Comprehensive Review on the Approach of Kidney Regeneration; Using Stem Cells." International Journal for Research in Applied Science and Engineering Technology 10, no. 7 (2022): 1700–1707. http://dx.doi.org/10.22214/ijraset.2022.45546.

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Abstract: Organ regeneration is an area of biomedical study that focuses on replacing an organ's cells to repair tissues and organs and partly or totally restore their original function. This article provides an overview of organ regeneration using stem cells and their potential use for treating kidney disorders. Compared to other organs, the kidney is a sensitive organ with a relatively low capability for regeneration. Renal disorder is becoming a public health concern. There are many progressive therapies to deal with such problems, but still mortality rates among subjects remained above ave
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Tvarožek, Samuel, Martina Szypulová, Anežka Šteflová, Martin Huser, and Zdeněk Rušavý. "Sexual function in women with pelvic organ prolapse." Česká gynekologie 90, no. 1 (2025): 64–70. https://doi.org/10.48095/cccg202564.

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A woman's sexuality is a complex phenomenon involving several factors, among which age and health are the most important. However, other aspects are not negligible. The impact of pelvic organ prolapse on sexual function cannot be ignored, as the reported prevalence of pelvic organ prolapse in female population exceeds 50%. This article presents a systematic review of articles dealing with the impact of pelvic organ prolapse on female sexual function. Sexual dysfunction is common in women with pelvic organ prolapse, regardless of prolapse stage or the compartment affected. Estrogen therapy has
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Jiang, Dongsheng, Ruiji Guo, Ruoxuan Dai, et al. "The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair." International Journal of Molecular Sciences 25, no. 2 (2024): 1179. http://dx.doi.org/10.3390/ijms25021179.

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The transient receptor potential vanilloid 4 (TRPV4) specifically functions as a mechanosensitive ion channel and is responsible for conveying changes in physical stimuli such as mechanical stress, osmotic pressure, and temperature. TRPV4 enables the entry of cation ions, particularly calcium ions, into the cell. Activation of TRPV4 channels initiates calcium oscillations, which trigger intracellular signaling pathways involved in a plethora of cellular processes, including tissue repair. Widely expressed throughout the body, TRPV4 can be activated by a wide array of physicochemical stimuli, t
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Hart, David A. "One of the Primary Functions of Tissue-Resident Pluripotent Pericytes Cells May Be to Regulate Normal Organ Growth and Maturation: Implications for Attempts to Repair Tissues Later in Life." International Journal of Molecular Sciences 23, no. 10 (2022): 5496. http://dx.doi.org/10.3390/ijms23105496.

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Adult mesenchymal stem cells were reported more than 30 years ago. Since then, their potential to repair and regenerate damaged or diseased tissues has been studied intensively in both preclinical models and human trials. Most of the need for such tissue repair/regeneration is in older populations, so much of the effort has been performed with autologous cells in older patients. However, success has been difficult to achieve. In the literature, it has been noted that such progenitor cells from younger individuals often behave with more vigorous activity and are functionally enhanced compared t
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Neupane, Bhanubhakta, Gyanendra Man Singh Karki, Hanoon Pokhrel, and Ashim Adhikari. "Assessment of Safety of Vaginal Repair of Pelvic Organ Prolapse in Elderly at Birat Medical College Teaching Hospital, Nepal." Journal of Nobel Medical College 10, no. 2 (2021): 20–25. http://dx.doi.org/10.3126/jonmc.v10i2.41580.

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Background: Pelvic organ prolapse in elder women causes sufficient morbidity and decreased quality of life. Despite age related comorbidities and decreased physiological capabilities, elder women with pelvic organ prolapse may be benefitted by surgical repair via vaginal route.The purpose of this study is to evaluate the safety of vaginal repair of pelvic organ prolapse in women of age 60 years or older.
 Materials and Methods: This hospital based analytical study was carried out in Birat Medical College Teaching Hospital from September 2020 to September 2021. Fifty-four patients aged 60
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Liu, Shu Q., Xin‐Liang Ma, Gangjian Qin, Qingping Liu, Yan‐Chun Li, and Yu H. Wu. "Trans‐System Mechanisms Against Ischemic Myocardial Injury." Comprehensive Physiology 5, no. 1 (2015): 167–92. https://doi.org/10.1002/j.2040-4603.2015.tb00606.x.

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AbstractA mammalian organism possesses a hierarchy of naturally evolved protective mechanisms against ischemic myocardial injury at the molecular, cellular, and organ levels. These mechanisms comprise regional protective processes, including upregulation and secretion of paracrine cell‐survival factors, inflammation, angiogenesis, fibrosis, and resident stem cell‐based cardiomyocyte regeneration. There are also interactive protective processes between the injured heart, circulation, and selected remote organs, defined as trans‐system protective mechanisms, including upregulation and secretion
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Shi, Donglu, Rigwed Tatu, Qing Liu, and Hossein Hosseinkhani. "Stem Cell-Based Tissue Engineering for Regenerative Medicine." Nano LIFE 04, no. 02 (2014): 1430001. http://dx.doi.org/10.1142/s1793984414300015.

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The applications of stem cells in tissue engineering will show great promise in generating tailor-made tissue/organs for clinical applications. This paper gives a review on a broad spectrum of areas in stem cell-based tissue engineering including neuron repair, cardiac patches, skin regeneration, gene therapy and cartilage tissue engineering. This paper is intended to serve as an informative tutorial for scientists and physicians from fields other than stem cells and tissue engineering. It will shed light on various strategies of target tissue/organ repair involving stem cells.
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Mungadi, IsmailaA. "Bioengineering Tissue for Organ Repair, Regeneration, and Renewal." Journal of Surgical Technique and Case Report 4, no. 2 (2012): 77. http://dx.doi.org/10.4103/2006-8808.110247.

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Vannella, Kevin M., and Thomas A. Wynn. "Mechanisms of Organ Injury and Repair by Macrophages." Annual Review of Physiology 79, no. 1 (2017): 593–617. http://dx.doi.org/10.1146/annurev-physiol-022516-034356.

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Cundiff, Geoffrey W., and Julia Van Rooyen. "Vaginal versus Abdominal Repair of Pelvic Organ Prolapse." Postgraduate Obstetrics & Gynecology 19, no. 23 (1999): 1–7. http://dx.doi.org/10.1097/00256406-199919230-00001.

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Purnell, B. "New Release: The Complete Guide to Organ Repair." Science 322, no. 5907 (2008): 1489. http://dx.doi.org/10.1126/science.322.5907.1489.

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Johnson, Justine R., Rachel A. High, Olivia Dziadek, et al. "Overactive Bladder Symptoms After Pelvic Organ Prolapse Repair." Female Pelvic Medicine & Reconstructive Surgery 26, no. 12 (2019): 742–45. http://dx.doi.org/10.1097/spv.0000000000000700.

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Vickers, Alison E. M., Robyn Fisher, Peter Olinga, and Sharon Dial. "Repair pathways evident in human liver organ slices." Toxicology in Vitro 25, no. 7 (2011): 1485–92. http://dx.doi.org/10.1016/j.tiv.2011.04.029.

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Tupikina, N. V., G. R. Kasyan, M. Gvozdev, B. Godunov, and D. Y. Pushkar. "70 Urgent incontinence after pelvic organ prolapse repair." European Urology Supplements 14, no. 2 (2015): e70. http://dx.doi.org/10.1016/s1569-9056(15)60072-0.

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Matalanis, George, and Brian F. Buxton. "Retrograde vital organ perfusion during aortic arch repair." Annals of Thoracic Surgery 56, no. 4 (1993): 981–83. http://dx.doi.org/10.1016/0003-4975(93)90374-q.

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Scheuerlein, H., F. Rauchfuss, A. Gharbi, M. Heise, and U. Settmacher. "Laparoscopic Incisional Hernia Repair After Solid-Organ Transplantation." Transplantation Proceedings 43, no. 5 (2011): 1783–89. http://dx.doi.org/10.1016/j.transproceed.2011.03.082.

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Seman, E., R. T. O'Shea, J. Cook, F. Behnia-Willison, C. Lam, and R. Vanspauwen. "Posterior Compartment Pelvic Organ Prolapse – Laparoscopic Supralevator Repair." Journal of Minimally Invasive Gynecology 15, no. 6 (2008): 36S. http://dx.doi.org/10.1016/j.jmig.2008.09.135.

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Sung, Vivian W., Rebecca G. Rogers, Joseph I. Schaffer, et al. "Graft Use in Transvaginal Pelvic Organ Prolapse Repair." Obstetrics & Gynecology 112, no. 5 (2008): 1131–42. http://dx.doi.org/10.1097/aog.0b013e3181898ba9.

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Patel, Bhavin N., Alvaro Lucioni, and Kathleen C. Kobashi. "Anterior Pelvic Organ Prolapse Repair Using Synthetic Mesh." Current Urology Reports 13, no. 3 (2012): 211–15. http://dx.doi.org/10.1007/s11934-012-0246-0.

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Kennealey, Peter T. "Laparoscopic Incisional Hernia Repair After Solid-Organ Transplantation." Archives of Surgery 144, no. 3 (2009): 228. http://dx.doi.org/10.1001/archsurg.2008.571.

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Yokoi, Akiko. "Could a Two-Staged Repair Be the Solution to the Dilemma of Repair Timing for Severe Congenital Diaphragmatic Hernia Requiring Extracorporeal Membrane Oxygenation?" Children 11, no. 10 (2024): 1255. http://dx.doi.org/10.3390/children11101255.

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Purpose of review: Congenital diaphragmatic hernia (CDH) remains a significant challenge, particularly in severe cases with persistent pulmonary hypertension (PPHN) and hypoplastic lungs and heart. For patients unresponsive to conventional therapies, ECMO is required. While the surgical repair is relatively simple, determining the optimal timing for surgery in patients requiring ECMO is particularly challenging. This review explores the dilemma of surgical timing and proposes a two-staged approach: a reduction in herniated organs and the creation of a silo to relieve abdominal pressure before
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48

Martins, Francisco E. "Pelvic Organ Prolapse and Sexual Dysfunction." Société Internationale d’Urologie Journal 6, no. 1 (2025): 19. https://doi.org/10.3390/siuj6010019.

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Introduction: This narrative review aims to investigate the intricacy of human sexuality, the prevalence and effect of pelvic organ prolapse (POP) repair on overall sexual function and dyspareunia, and the subsequent repercussions on body image self-perception and quality of life. Methods: A MEDLINE and PUBMED search was conducted for studies evaluating the effect of POP surgery on sexual function and dyspareunia in sexually active women as well as its impact on body image self-perception and QoL. We included both observational and randomized controlled studies evaluating this subject. We eval
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Buggs, Jacentha, Anthony Brando, Julio Sokolich, Ebonie Rogers, Ambuj Kumar, and Victor Bowers. "Incisional Hernia Repairs after Abdominal Organ Transplantation." American Surgeon 85, no. 8 (2019): 918–22. http://dx.doi.org/10.1177/000313481908500848.

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Incisional hernias occur after abdominal organ transplantation with rates of 1.6 per cent to 18 per cent in kidney transplants (KTs) and 1.7 to 32.4 per cent in liver transplants (LTs). We hypothesized a difference in KTand LToutcomes in patients with and without repair of incisional hernias. We conducted a retrospective cohort study of abdominal transplants from 2012 through 2016. The difference across compared groups for continuous variables was assessed using the independent sample t test, and for binary variables, using the chi-squared test. A total of 1518 transplants were performed, incl
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Jin, Zhirui. "Research Progress on Tissue Engineering of Main Tissues and Organs of Human Body." E3S Web of Conferences 245 (2021): 03043. http://dx.doi.org/10.1051/e3sconf/202124503043.

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The injury and failure diseases of human tissues and organs, such as heart failure and chronic kidney disease, seriously threaten human health and life safety. At present, however, organ transplantation has obvious limitations, and tissue engineering is considered as a potential alternative therapy. Tissue engineering uses the construction of cells, biomaterials and bioreactors to develop three-dimensional artificial tissues and organs for the enhancement, repair and replacement of damaged or diseased tissues and organs, which contributes to the fundamental solutions of diseases of tissues and
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