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1

Lott, Donovan J., Katrina S. Maluf, David R. Sinacore, and Michael J. Mueller. "Relationship Between Changes in Activity and Plantar Ulcer Recurrence in a Patient With Diabetes Mellitus." Physical Therapy 85, no. 6 (2005): 579–88. http://dx.doi.org/10.1093/ptj/85.6.579.

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Abstract Background and Purpose. Although pressure-reducing interventions have been effective in the healing of neuropathic foot ulcers, these ulcers frequently recur in people with diabetes mellitus (DM). This case report illustrates how sudden changes in weight-bearing activity may have affected ulcer recurrence in a patient with DM and how the physical stress theory (PST) relates to ulcer recurrence for this patient. Case Description. The patient was a 66-year-old man with a history of DM, peripheral neuropathy, and recurrent plantar ulcers. His plantar ulcer healed after total contact cast
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Lv, Xiaoying, and Yaxiong Guo. "Research Progress on Traditional Chinese Medicine Treatment of Recurrent Oral Ulcers in Children." Journal of Contemporary Medical Practice 7, no. 1 (2025): 197–200. https://doi.org/10.53469/jcmp.2025.07(01).37.

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Objective: To analyze and discuss the treatment of recurrent oral ulcers with traditional Chinese medicine (TCM), in order to provide a reference for the treatment of recurrent oral ulcers and other related oral diseases with TCM in the future. Methods: The key words “recurrent oral ulcers in children” or “recurrent aphthous ulcers in children” and the Chinese medical names “aphthous ulcers”, “aphthous ulcers”, “mouth ulcer”, “mouth erosion”, etc., and secondary searches with “Chinese medicine”, “combination of Chinese and Western medicine”, etc. were performed. A secondary search with “Chines
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Christenson, J. T., C. Prins, and G. Gemayel. "Subcutaneous fasciotomy and eradication of superficial venous reflux for chronic and recurrent venous ulcers: mid-term results." Phlebology: The Journal of Venous Disease 26, no. 5 (2011): 197–202. http://dx.doi.org/10.1258/phleb.2010.010026.

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Objective Increased intramuscular and subcutaneous tissue pressures are often found in patients with severe chronic venous insufficiency venous ulcer disease. Additional subcutaneous para-tibial fasciotomy promotes early ulcer healing. This study evaluates the mid-term effect of eradication of superficial reflux with additional fasciotomy in patients with increased tissue pressures. Method Between January 2006 and June 2009, 58 patients underwent fasciotomy. Tissue pressures (intramuscular and subcutaneous) were measured. Sixty-nine limbs with 91 venous ulcers were treated. Mean duration of th
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Potra-Cicalău, G. I., I. Scrobotă, G. Iova, L. Todor, G. Ciavoi, and R. C. Iurcov. "Recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS) enigmatic etiopathology." Medicine in Evolution 29, no. 2 (2023): 136–41. http://dx.doi.org/10.70921/medev.v29i2.1011.

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Oral aphthous ulcer is a well-known condition that significantly affects the quality of life for patients by producing intense pain and difficulties in speaking and chewing. When recurrence is present we refer to them as recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS). Mouth ulcers are typically uncomfortable sores that can occur as a result of a variety of local and general disorders. It is one of the most prevalent oral ulcerative conditions.
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Tabanjeh, Sinan F., Dana Hyassat, Hashem Jaddou, Nidal A. Younes, Asirvatham A. Robert, and Kamel Ajlouni. "The Frequency and Risk Factors of Diabetic Foot Ulcer Recurrence Among Jordanian Patients with Diabetes." Current Diabetes Reviews 16, no. 8 (2020): 910–15. http://dx.doi.org/10.2174/1573399816666200109094329.

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Background: Diabetic foot is a major public health problem and their complications are an imperative cause of morbidity and mortality in diabetes. Objective: To evaluate the rate of recurrence of foot ulcers post two years of follow-up, including the associated risk factors in the patients attending the diabetic foot clinic at the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), Amman, Jordan. Methods: A historical cohort design was adopted for the patients who presented for the first time to the diabetic foot clinic at the NCDEG. Every patient who came to the clinic was revi
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Manggasa, Dafrosia Darmi, Agusrianto Agusrianto, and Rosamey Elleke Langitan. "Family Support As A Determinant Of Foot Care Compliance In Recurrent Diabetic Foot Wounds." Jurnal Riset Kesehatan 13, no. 2 (2024): 81–88. https://doi.org/10.31983/jrk.v13i2.11444.

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As many as 15-25% of Diabetes Mellitus (DM) patients have the potential to experience diabetic foot ulcers and the rate of recurrence or recurrence of diabetic ulcers is 50% to 70% over 5 years. A quarter of patients with Diabetes Mellitus have the potential to develop diabetic foot sores or diabetic ulcers and more than half to 70% have a recurrence of diabetes mellitus over 5 years. Recurrent diabetic ulcers have various impacts such as reduced quality of life, economic burden, and psychological, and social effects, even if not treated properly, they can lead to infection, amputation, and ev
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7

Morgan, Earl P., and C. N. Williams. "Complete Response of Severe, Refractory, Gastric, Stomal and Sclerotherapy-Induced Esophageal Ulcer Disease to Omeprazole Therapy." Canadian Journal of Gastroenterology 3, no. 5 (1989): 179–81. http://dx.doi.org/10.1155/1989/293596.

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This report presents three unusual forms of resistant peptic ulcer disease, all healed completely with the use of a new class of anti-ulcer drug, a proton pump blocker, omeprazole. Each of these patients represents an unusual facet of acid-pepsin disease, namely, resistance to healing with current standard therapy, recurrence and rehealing with a second course of omcprazole, and a subsequent need for maintenance omeprazole to remain ulcer-free. The first patient had an unusual complication of a stomal ulcer after gastric bypass surgery for morbid obesity. This ulcer proved to be intractable, n
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8

Jin, Ying, Xiaoping Lin, Liming Song, et al. "The Effect of Pudilan Anti-Inflammatory Oral Liquid on the Treatment of Mild Recurrent Aphthous Ulcers." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/6250892.

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Recurrent aphthous ulcers are the most common recurrent oral mucosal lesions characterized by recurrence and pain. The aim of this research is to evaluate the short-term curative effect of the traditional Chinese medicine “Pudilan anti-inflammatory oral liquid” on mild recurrent aphthous ulcers. A total of 234 patients were divided into a treatment group and a control group. Both groups used vitamin B2 as the basis of treatment. The treatment group took a Pudilan anti-inflammatory oral solution for 8 days while the control group was given a liquid placebo. The ulcer size, pseudomembrane, perip
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9

Rujirekasuwan, Nuanwan, Panpicha Sattasathuchana, Natthanet Sritrakoon, and Naris Thengchaisri. "Recurrent vs. Nonrecurrent Superficial Non-Healing Corneal Ulcers in Cats: A Multifactorial Retrospective Analysis." Animals 15, no. 14 (2025): 2104. https://doi.org/10.3390/ani15142104.

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Feline superficial non-healing corneal ulcers are persistent lesions requiring individualized treatment to reduce recurrence. This retrospective study evaluated 136 affected eyes (113 nonrecurrent; 23 recurrent) to identify clinical and treatment-related factors associated with recurrence. Recurrent ulcers were more common in older cats (7.2 ± 4.3 vs. 5.1 ± 4.6 years; p = 0.026). Domestic Shorthairs were the most frequently affected breed (50%), and central ulcer location predominated in both groups. Recurrent cases required more intensive management, with 16.9% needing ≥ 2 treatment courses,
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10

Beiras, Camila G., Michael Marks, Llorenç Quintó, et al. "Yaws recurrence in children at continued risk of infection." PLOS Neglected Tropical Diseases 16, no. 3 (2022): e0010197. http://dx.doi.org/10.1371/journal.pntd.0010197.

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Background In yaws-endemic areas, children with Treponema pallidum subsp. pertenue infection may suffer recurrent episodes due to either reinfection or relapse. However, the possibility of infection with other cutaneous ulcer causative agents and difficulties in interpreting standard laboratory results challenges the estimation of yaws recurrence rates. Methods We estimated the rates of yaws recurrences in the Lihir Island (Papua New Guinea) using two approaches: passive surveillance based on a retrospective screening of electronic medical records of cutaneous ulcers diagnosed using serologica
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11

Vashishat, Bhart, Shruti Sinha, Tanmay Srivastava, et al. "Management of oral aphthous ulcer: A review." Bioinformation 20, no. 5 (2024): 434–38. http://dx.doi.org/10.6026/973206300200434.

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Aphthous ulcers, also known as canker sores, are a common oral condition characterized by recurrent, painful, small ulcers that typically arise on the non-keratinized mucous membranes within the mouth. Although the pathogenesis of aphthous ulcers is not completely understood; it is believed to be involved in a combination of genetic predisposition, local trauma, stress, hormonal changes, and certain environmental factors. Thus, management of aphthous ulcer revolves around reducing pain, promoting healing and preventing recurrence.
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12

Sari, Rina Kartika, Diah Savitri Ernawati, and Bagus Soebadi. "RECURRENT APHTHOUS STOMATITIS RELATED TO PSYCHOLOGICAL STRESS, FOOD ALLERGY AND GERD." ODONTO : Dental Journal 6 (July 11, 2019): 45. http://dx.doi.org/10.30659/odj.6.0.45-51.

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Background: Recurrent Aphthous Stomatitis (RAS) is inflammation in oral mucosa characterized by recurrent single or multiple ulcers that usually affected in non keratinized mucosa. Etiology RAS is unknown but psychological stress, allergy, and gastrointestinal disease can be predisposing factors Case Management: A 23rd years old complained recurrent oral ulcer with free ulcer period for 3-5 days. The patient had a history of food allergy, GERD and psychological stress. Intraoral examination showed recurrent multiple ulcers in variation site of the mouth. DASS 42 screening showed high stress an
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13

Kathirvel, Manikandan, Viswakumar Prabakaran, Jayalakshmi Jayarajan, Ajay Sivakumar, and Vimalkumar Govindan. "Risk factors for the diabetic foot infection with multidrug-resistant microorganisms in South India." International Surgery Journal 5, no. 2 (2018): 675. http://dx.doi.org/10.18203/2349-2902.isj20180374.

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Background: To analyse the risk-factors contributing to infection with multidrug-resistant organisms.Methods: 150 diabetic patients with foot ulcer were prospectively studied. Detailed clinical history and clinical examination of the ulcer were done for all patients. The microbiological profile was analyzed for each patient. Using internationally accepted criteria, the multidrug-resistant organisms were identified. Risk factors for acquiring MDRO infection were identified using appropriate statistical tools.Results: MDRO were isolated from 99 patients of 150 (66%). 54.8% (153 out of 279) of is
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14

Leichliter, Jami S., and David A. Lewis. "Correlates of bacterial ulcers and acute HSV-2 infection among men with genital ulcer disease in South Africa: age, recent sexual behaviours, and HIVi,ii." Southern African Journal of Infectious Diseases 31, no. 2 (2016): 61–65. http://dx.doi.org/10.4102/sajid.v31i2.92.

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Data from baseline surveys and STI/HIV laboratory tests (n=615 men) were used to examine correlates of bacterial ulcers (Treponema pallidum, Haemophilus ducreyi, or Chlamydia trachomatis L1-L3 detected in ulcers) and acute HSV-2 ulcers (HSV-2 positive ulcer specimen, HSV-2 sero-negative, and negative for bacterial pathogens) versus recurrent HSV-2 ulcers (seropositive), separately. Men with bacterial ulcers had larger ulcers compared to men with recurrent HSV-2 ulcers, but were less likely to be HIV-positive; whereas, men with acute HSV-2 ulcers were younger with fewer partners. Acute HIV was
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15

Burm, Jin Sik, Eunchoang Cha, and Jun Park. "Consistent Reconstruction of Sacrococcygeal Pressure Ulcers using Modification of En Bloc Sliding Gluteus Maximus Myocutaneous Flap Technique." Journal of Wound Management and Research 20, no. 1 (2024): 46–54. http://dx.doi.org/10.22467/jwmr.2023.02838.

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Background: The en bloc sliding gluteus maximus myocutaneous flap was introduced to preserve the vasculature, muscular integrity, sensory innervation, and normal gluteal contour with a midline scar in sacrococcygeal pressure ulcer reconstruction. However, its critical disadvantages include incomplete detachment of the origin of the gluteus maximus and central tension of the closed wound due to round ulcer excision. Therefore, we reviewed the surgical anatomy and applied modifications to achieve sufficient flap mobilization and to decrease complications.Methods: After fusiform or rocket-shaped
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16

Manukonda, Deepthi Chandrika, Pavan Kumar Yellarthi, Suresh Kumar Pakki, N. V. V. Satya Bhushan, G. V. Radha, and Venkata Ramani Chintada. "Comparative Evaluation of Tacrolimus 0.1% in Orabase and Triamcinolone Acetonide 0.1% in the Management of Recurrent Apthous Stomatitis (RAS) – A Case Control Study." Journal of Pharmacy and Bioallied Sciences 16, Suppl 4 (2024): S4107—S4110. https://doi.org/10.4103/jpbs.jpbs_1498_24.

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ABSTRACT Background: Recurrent apthous stomatitis (RAS) and recurrent apthous ulcers are common oral ulcers which are associated with a significant amount of pain and reduction in quality of life, where traditional mainstay of treatment is topical steroids. Methodology: A case control study was undertaken on 90 patients seeking treatment for minor RAS and was divided into three groups. An index ulcer was selected and treated with 0.1% tacrolimus, 0.1% triamcinolone acetonide, and placebo, respectively, for 1 week. Results: At the end of day 2, the mean percentage reduction was 44.16%, 79.82% a
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17

Udovichenko., О. V., A. Yu Tokmakova, M. B. Antsiferov, P. V. Yushkov, and I. I. Dedov. "Clinical and morphological features of reparative processes in patients with the diabetic foot syndrome." Problems of Endocrinology 49, no. 1 (2003): 20–25. http://dx.doi.org/10.14341/probl11402.

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The purpose of the study was to examine structural abnormalities in the skin and granulation tissue, which explain long-term heal­ing and recurrent trophic ulcers in patients with the neuropathic diabetic foot syndrome who received adequate treatment. Biopsy specimens were taken from the granulation tissue and skin of the edge of a trophic ulcer in 12 patients (mean age 48.4+6.6 years) with types 1 and 2 diabetes mellitus (its duration was 14.0+4. 7 years). All the patients were treated for the neuropathic diabetic foot syndrome according to the generally accepted recommenda­tions. According t
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18

Al Abri, MD, Maather, Ghaitha Al Mahruqi, MD, and Hani Al Qadhi, FRCSC. "Recurrent Peptic Ulcer Perforation: A Case Report." International Journal of Innovative Research in Medical Science 7, no. 01 (2022): 62–65. http://dx.doi.org/10.23958/ijirms/vol07-i01/1329.

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Background: Refractory peptic ulcers are ulcers in the stomach or duodenum that do not heal after eight to twelve weeks of medical/surgical treatment or those that are associated with complications despite medical tssreatment. We herein present a case of a 44 year old man with a recurrent perforated duodenal ulcer requiring emergent surgical intervention.
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Mueller, Michael J., Kirk E. Smith, Paul K. Commean, Douglas D. Robertson, and Jeffrey E. Johnson. "Use of Computed Tomography and Plantar Pressure Measurement for Management of Neuropathic Ulcers in Patients With Diabetes." Physical Therapy 79, no. 3 (1999): 296–307. http://dx.doi.org/10.1093/ptj/79.3.296.

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AbstractBackground and Purpose. Total contact casting is effective at healing neuropathic ulcers, but patients have a high rate (30%–57%) of ulcer recurrence when they resume walking without the cast. The purposes of this case report are to describe how data from plantar pressure measurement and spiral x-ray computed tomography (SXCT) were used to help manage a patient with recurrent plantar ulcers and to discuss potential future benefits of this technology. Case Description. The patient was a 62-year-old man with type 1 diabetes mellitus (DM) of 34 years' duration, peripheral neuropathy, and
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20

Wilson, Anushka, Bandhavi Muppalla, Yamini Vijaya Sai Koneru, et al. "A clinicoepidemiological study of chronic and recurrent leg ulcers." IP Indian Journal of Clinical and Experimental Dermatology 10, no. 3 (2024): 328–32. http://dx.doi.org/10.18231/j.ijced.2024.058.

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Chronic leg ulcers (CLU) are chronic diseases, which are associated with significant morbidity and exert health burden on the patients. Varied heterogeneity in the type of aetiology, risk factors, and comorbidities have been observed in individuals with CLU. Aprospective, cross-sectional, observational type of descriptive study carried out in the department of Dermatology, Venereology and Leprosy at a tertiary care teaching hospital in Navi Mumbai. Adult patients with clinical evidence of chronic leg ulcer were enrolled. Patient’s quality of life (QOL) was assessed by Dermatology Life Quality
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21

Prathoshini, Manthra. "Management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements." Bioinformation 16, no. 12 (2020): 992–98. http://dx.doi.org/10.6026/97320630016992.

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Recurrent Aphthous ulcers are the most common oral lesions among dental patients. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and swallowing. Therefore, it is of interest to report data on the management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements. Case sheets of 76 patients who underwent treatment for recurrent aphthous ulcer between June 2019 and March 2020 at the Saveetha Dental College, India were used in this analysis. Data was analyzed using Chi
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Prathoshini, Manthra. "Management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements." Bioinformation 16, no. 12 (2020): 992–98. http://dx.doi.org/10.6026/97320630016992.

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Recurrent Aphthous ulcers are the most common oral lesions among dental patients. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and swallowing. Therefore, it is of interest to report data on the management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements. Case sheets of 76 patients who underwent treatment for recurrent aphthous ulcer between June 2019 and March 2020 at the Saveetha Dental College, India were used in this analysis. Data was analyzed using Chi
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23

Wang, Dan. "New Progress in the Integrated Treatment of Traditional Chinese and Western Medicine for Recurrent Aphthous Ulcer in the Oral Cavity." International Journal of Public Health and Medical Research 1, no. 3 (2024): 85–87. http://dx.doi.org/10.62051/ijphmr.v1n3.12.

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Recurrent aphthous ulcer in the oral cavity is a common oral mucosal disease with periodic, recurrent, and self-limiting characteristics. This article aims to explore the new progress of integrated traditional Chinese and Western medicine in the treatment of recurrent aphthous ulcers in the oral cavity. Through a comprehensive analysis of relevant research, the advantages and mechanisms of integrated traditional Chinese and Western medicine in improving efficacy, reducing symptoms, and reducing recurrence rates are elaborated, providing reference for clinical treatment.
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24

Kenneweg, K. A., M. C. Welch, and P. J. Welch. "A 9-year retrospective evaluation of 102 pressure ulcer reconstructions." Journal of Wound Care 29, Sup9a (2020): S48—S56. http://dx.doi.org/10.12968/jowc.2020.29.sup9a.s48.

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• Objective: Several pressure ulcer (PU) risk factors including paralysis and age greater than 70 have been identified, while others such as nutrition are debated. The object of this study is to identify perioperative risk factors that may predict improved outcomes and reduced complications in primary and recurrent PU reconstructions. • Method: A retrospective chart review of patients treated surgically for PUs from 2004 to 2013 at the University of Toledo Medical Center, Toledo, Ohio, US, was completed. Data collected included ulcer and medical history, as well as risk factors, complications
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Zhu, Wei, and Huapei Song. "A Rare Case of Recurrent Lower Extremity Ulcer." International Journal of Lower Extremity Wounds 18, no. 4 (2019): 389–92. http://dx.doi.org/10.1177/1534734619870098.

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Venous leg ulcers are a manifestation of lower extremity chronic venous disorder. Venous hypertension caused by abnormal venous blood flow is considered to be the primary mechanism of venous ulcers. The etiology of lower extremity venous ulcer is complicated, and it is difficult to be treated. At present, it has achieved a certain effect for venous leg ulcers through the combination of drugs, pressure therapy, and surgical treatment. Budd-Chiari syndrome is a rare syndrome characterized by portal hypertension and/or inferior vena cava syndrome. Treatment of Budd-Chiari syndrome includes antico
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26

Yuan, Mandi. "Comparative analysis of the therapeutic effect of traditional chinese medicine and western medicine on ROU." Theoretical and Natural Science 66, no. 1 (2024): 135–40. https://doi.org/10.54254/2753-8818/2024.17999.

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The prevalence of recurrent oral ulcer is as high as 50%. It is generally more prevalent in women than in men, and it typically occurs between the ages of 10 and 30. Surveys indicate that at least 10% to 25% of people have experienced this disease. This disease is characterized by cyclical, recurrent, self-limited symptoms of burning pain. Currently, there is no specific drug treatment available for recurrent oral ulcers, making it a major challenge in the academic field. This paper examines the efficacy of different medications in treating recurrent oral ulcers through literature review, data
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Nzhad Mustafa, Bero, and Ali Fakhree Alzubaidee. "Comparative Evaluation of The Efficacy of Topical Hyaluronic Acid ( 0.2%) and Topical Triamcinolone Acetonide( 0.1%) in The Treatment of Recurrent Aphthous Stomatitis." Diyala Journal of Medicine 19, no. 2 (2020): 107–17. http://dx.doi.org/10.26505/djm.19025470628.

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Background: Recurrent aphthous ulcers are the most common oral lesion. They are classified into minor, major, and herpetiform ulcers. More than 85% of recurrent aphthous stomatitis presents as a minor ulcer. Hyaluronic acid is a biomaterial and it is a major carbohydrate component that can be found in many tissues and recently introduced as an alternative approach to enhance wound healing. Triamcinolone acetonide is a synthetic corticosteroid and it has two forms for topical use cream (0.1%) and ointment (0.1%). Objective: To make a comparison between the effectiveness of hyaluronic acid (0.2%
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Wong, Grace L. H., Louis H. S. Lau, Jessica Y. L. Ching, et al. "Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial." Gut 69, no. 4 (2019): 652–57. http://dx.doi.org/10.1136/gutjnl-2019-318715.

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ObjectivePatients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have a considerable risk of recurrent ulcer complications. We hypothesised that a proton pump inhibitor (lansoprazole) is superior to a histamine 2 receptor antagonist (famotidine) for the prevention of recurrent ulcer bleeding in such patients.DesignIn this industry-independent, double-blind, randomised trial, we recruited patients with a history of idiopathic bleeding ulcers. After ulcer healing, we randomly assigned (1:1) patients to receive oral lansoprazole 30 mg or famotidine 40 mg daily for 24 mo
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Haryanto, Haryanto, Makoto Oe, Tutur Kardatun, et al. "Risk Factors of Recurrent Diabetic Foot Ulcers Based on the Delphi Method." Iranian Journal of Nursing and Midwifery Research 29, no. 1 (2024): 56–59. http://dx.doi.org/10.4103/ijnmr.ijnmr_391_21.

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Abstract Background: The risk factors for recurrence are poorly understood. The purpose of study is to investigate the risk factors that contribute to the recurrence of diabetic foot ulcers. Materials and Methods: This is a cross-sectional study, and the two-phase Delphi method was used. A category was developed to investigate the risk factors of recurrent diabetic foot ulcers by experts. The recurrent items with risk factors were analyzed. Furthermore, the risk factor variables were clinically tested for inter-rater reliability agreement. Fourteen experts and two patients were included from F
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Chen, Wen-Chi, Yun-Da Li, Po-Hung Chiang, et al. "Comparison of Proton Pump Inhibitor and Histamine-2 Receptor Antagonist in the Prevention of Recurrent Peptic Ulcers/Erosions in Long-Term Low-Dose Aspirin Users: A Retrospective Cohort Study." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/693567.

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Background. Proton pump inhibitor and histamine-2 receptor antagonist can prevent aspirin-related ulcers/erosions but few studies compare the efficacy of these two agents.Aims. We evaluated the efficacy of omeprazole and famotidine in preventing recurrent ulcers/erosions in low-dose aspirin users.Methods. The 24-week clinical outcomes of the patients using low-dose aspirin for cardiovascular protection with a history of ulcers/erosions and cotherapy of omeprazole or famotidine were retrospectively reviewed. The incidence of gastrointestinal symptoms, recurrent ulcers/erosions, erosive esophagi
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Yavuz, Celal, Sinan Demirtas, Orkut Guclu, et al. "An Alternative Therapy for Recurrent Stasis Ulcers in Chronic Venous Insufficiency: Venocuff." Case Reports in Vascular Medicine 2012 (2012): 1–2. http://dx.doi.org/10.1155/2012/315147.

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Chronic venous insufficiency may cause stasis ulcers that significantly impact on the quality of life. Many methods have been described for preventing or treating these ulcers. However, stasis ulcers often recur as a result of continuing venous insufficiency. Here we report a 30-year-old male patient with chronic venous insufficiency. He was admitted to the hospital owing to recurrent stasis ulcers. He had a history of various flavonoid drug usage and compression therapies over the previous six years. Venous Doppler sonography revealed combined saphenofemoral and deep femoral venous insufficie
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Arwyn-Jones, James, and Ashwin Kerai. "Recurrent mouth ulcers." InnovAiT: Education and inspiration for general practice 12, no. 3 (2019): 137–43. http://dx.doi.org/10.1177/1755738018794719.

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Mouth ulcers are common and produce a variety of symptoms, ranging from intermittent discomfort to debilitating pain with effects on speech, chewing and swallowing. Clinically, mouth ulcers can be challenging, as a wide range of diagnoses can give rise to lesions of similar appearance. Although the majority of lesions are benign and require little clinical input, others may signify undiagnosed systemic disease or malignancy, warranting prompt investigation and treatment. Separation of differential diagnoses is driven largely by a thorough history and identification of malignant features on exa
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Field, Anne, and Jennifer Field. "Recurrent Mouth Ulcers." InnovAiT: Education and inspiration for general practice 4, no. 1 (2010): 12–15. http://dx.doi.org/10.1093/innovait/inq149.

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Aderaye, G. "Recurrent aphthous ulcers." Tobacco Control 4, no. 4 (1995): 399–400. http://dx.doi.org/10.1136/tc.4.4.399b.

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Bhanja, Dibyendu Bikash, Abheek Sil, Avik Panigrahi, and Surajit Kumar Biswas. "Recurrent Genital Ulcers." Urology 147 (January 2021): 33–34. http://dx.doi.org/10.1016/j.urology.2020.10.019.

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Johnston, David, and Richard L. Blackett. "Recurrent peptic ulcers." World Journal of Surgery 11, no. 3 (1987): 274–82. http://dx.doi.org/10.1007/bf01658103.

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Stoopler, Eric T., and Thomas P. Sollecito. "Recurrent Oral Ulcers." JAMA 313, no. 23 (2015): 2373. http://dx.doi.org/10.1001/jama.2015.1637.

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Drumm, Brendan, J. Marc Rhoads, David A. Stringer, Phillip M. Sherman, Lynda E. Ellis, and Peter R. Durie. "Peptic Ulcer Disease in Children: Etiology, Clinical Findings, and Clinical Course." Pediatrics 82, no. 3 (1988): 410–14. http://dx.doi.org/10.1542/peds.82.3.410.

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The records of all children with peptic ulcer disease at the Hospital for Sick Children were retrospectively evaluated, excluding neonates, throughout a 5-year period. Only cases with a definite ulcer crater identified either at endoscopy or at surgery were included. There were 36 patients, 20 boys and 16 girls. Duodenal ulcers were more common than gastric ulcers (2.8:1). Ages ranged from 3 months to 17 years, with a mean age of 10 years. Patients were reviewed with respect to etiology of peptic ulcer disease, age when first examined, initial symptoms, and clinical course. Patients were divid
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Al-Bayati, Sura Ali Ahmed Fuoad. "A Case Report of Major Aphthous Ulcer." International Journal of Membrane Science and Technology 10, no. 2 (2023): 3390–95. http://dx.doi.org/10.15379/ijmst.v10i2.3124.

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Recurrent aphthous ulceration (RAU) is the most common ulcerative condition following traumatic ulcer that affects the oral cavity. It has three clinical presentations, major, minor and herpitiform aphthous ulceration, all are painful and mostly occur on non-keratinized mucosa. If not secondary infected it will heal spontaneously without leaving scar. Our patient was suffering from recurrent ulcers and one single large ulcer that prevent him from swallowing. Following a comprehensive history and clinical examination, interpreting the clinical findings, the ulcers had been diagnosed as aphthous
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Borst, Johanna, and Lawrence Ma. "Oral ulcerations in a patient with autosomal dominant hyper-IgE syndrome (AD-HIES)." BMJ Case Reports 13, no. 11 (2020): e236705. http://dx.doi.org/10.1136/bcr-2020-236705.

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A 23-year-old woman with autosomal dominant hyper-IgE syndrome complicated by recurrent pneumonia and sinusitis presented with 1 week of multiple painful oral ulcers unresponsive to empiric antiviral and antifungal treatment. Her ulcers progressively worsened and she required hospitalisation for intravenous hydration and pain control. PCR swab of an ulcer was positive for varicella-zoster virus. Her symptoms never fully resolved despite antiviral therapy, and within 2 weeks, she relapsed with new and worsening ulcers. Biopsy revealed chronic active inflammation with no evidence of viral inclus
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He, Yuqi, Zhiqiang Xu, Zhuwen Qiu, Dechun Zheng, and Liting Xie. "Evaluation of the Efficacy and Performance of a New Nano-Drug Carrier in the Treatment of Recurrent Oral Ulcerper." Journal of Nanoscience and Nanotechnology 21, no. 2 (2021): 1107–17. http://dx.doi.org/10.1166/jnn.2021.18679.

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Recurrent oral ulcer is a common oral mucosal disease. Due to its periodic and recurrent characteristics, the onset of burning pain is unbearable, which brings great inconvenience to the patient’s life and seriously affects the patient’s quality of life. There are certain limitations to conventional drug therapy. With the rapid development of nanotechnology, the obvious advantages of nanotechnology such as targeting, controlled release, biocompatibility is obviously shown. The combination of nanotechnology and medical research has led to the emergence of polymer nanoparticles and ligands. Nano
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Hariprasad, Shetty, and Laxmi Shankar Yadav Subhash. "The Effect of Continuing Aspirin at a Low Dose in Peptic Ulcer Bleeding." International Journal of Pharmaceutical and Clinical Research 14, no. 12 (2022): 1105–11. https://doi.org/10.5281/zenodo.13882424.

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<strong>Introduction:</strong>&nbsp;Aspirin was once used to reduce swelling and pain, but because of its capacity to prevent blood vessels from clotting, this application has now changed. Many studies have found that patients who get a combination of antiplatelet drugs are more prone to experience gastrointestinal bleeding. Asymptomatic ulcers are nevertheless a major problem since they can injure the GI tract permanently even though they are commonly spotted and acknowledged. In particular, among the elderly population, aspirin use has increased to treat cardiovascular and brain conditions.&
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Sayani, J., and M. Tiruveedhula. "A TWO-STAGE APPROACH IN MANAGING DIABETIC FOREFOOT ULCERS." Orthopaedic Proceedings 106-B, SUPP_13 (2024): 16. http://dx.doi.org/10.1302/1358-992x.2024.13.016.

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AimForefoot ulcers in patients with diabetic neuropathy are a result of factors that result in increased forefoot plantar pressures. Progressive hindfoot equinus from contraction of gastrocnemius-soleus-tendo-Achilles complex and progressive plantar flexed metatarsal heads secondary to claw toe deformity results callus at the metatarsal heads which break down to ulceration. The aim is to describe 2-stage treatment pathway for managing these ulcers.MethodsConsecutive patients, who presented with forefoot ulcers since February 2019 were treated with a 2-stage treatment pathway. The first stage o
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Apelqvist, Jan, Gunnel Ragnarson-Tennvall, Jan Larsson, and Ulf Persson. "Long-Term Costs for Foot Ulcers in Diabetic Patients in a Multidisciplinary Setting." Foot & Ankle International 16, no. 7 (1995): 388–94. http://dx.doi.org/10.1177/107110079501600702.

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The purpose of this study was to analyze long-term costs for foot ulcers in diabetic patients. Patients were treated and followed prospectively by a foot care team. A retrospective economic analysis was performed of costs for 274 patients during 3 years from healing of an initial foot ulcer, with or without amputation. Costs were estimated for inpatient care, outpatient care, home care, and social service. The cost calculations include costs due to complications and disability related to the initial ulcer, costs related to recurrence of ulcer, and costs for prevention of new ulcers. Expected t
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Fomina, L. A. "Calcium imbalance in comorbid gastroduodenal ulcers." Medical alphabet, no. 35 (December 18, 2021): 30–33. http://dx.doi.org/10.33667/2078-5631-2021-35-30-33.

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Purpose of the study. To study the level of blood calcium, reflecting the functional state of the calcium-regulating system (CRS), in the comorbid course of gastroduodenal ulcers (GDU) with chronic erosive gastritis / chronic erosive duodenitis (CEG/CED), arterial hypertension (AH), their symptomatic nature when taking non-steroidal drugs (NSAIDs) and find out its effect on the activity of the ulcerous process, the state of regional microcirculation and the secretory function of the stomach.Materials and methods. 132 patients with GDU were examined. All patients were divided into groups: the f
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Taher, Aya K., and Nada Jafer MH Radhi. "Gingival health status in relation to salivary irisin in oral ulcerative patients of Diyala city, Iraq." Sumer 1 8, CSS 1 (2023): 1–6. http://dx.doi.org/10.21931/rb/css/s2023.08.01.11.

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Background: Gingivitis is the inflammation of the gingival tissue around the teeth initiated by bacteria. Irisin is a newly identified novel anti-inflammatory effect of adipocytokine. Recurrent aphthous ulcer (RAU) remains the most common ulcerative disease in the mucosa tissue of the oral cavity, existing as repeated onset of single or multiple painful ulcers. The study aims to evaluate gingival health status in relation to salivary irisin in oral ulcerative patients of Diyala City/ Iraq. The total sample consists of 200 patients taken from the specialized dental center in Ba'aquba / Diyala g
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Berardi, Rosemary R., Maureen E. Savitsky, and Timothy T. Nostrant. "Maintenance Therapy for Prevention of Recurrent Peptic Ulcers." Drug Intelligence & Clinical Pharmacy 21, no. 6 (1987): 493–501. http://dx.doi.org/10.1177/106002808702100602.

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Peptic ulcer disease is a chronic, relapsing disease. Successful healing of duodenal and gastric ulcers with antacids, cimetidine, ranitidine, famotidine, or sucralfate is frequently followed by ulcer recurrence. The need for long-term, low-dose maintenance therapy is based on disease severity, ulcer history, complications, therapeutic intervention, response to treatment, and potential risk factors. Comparison of ulcer maintenance trials requires consideration of important factors such as frequency of endoscopy, duration of follow-up period, and the method used to calculate ulcer recurrence ra
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Hernawati, Sri. "Management of Recurrent Aphthous Stomatitis in a Patient with High Recurrence Frequency." Health Notions 4, no. 4 (2020): 102–8. http://dx.doi.org/10.33846/hn40401.

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RAS (Recurrent Aphthous Stomatitis) is an inflammation of soft tissues of the oral cavity characterized by recurrent and painful ulcers. These lesions can be marked early on with a burning sensation, and when the wound has formed, the pain is getting worse. Occasional symptoms of precursors, paresthesia and hyperesthesia, are sometimes reported. Pain and discomfort arise along movement around the ulcer e.g. eating, talking and swallowing. Characteristics of RAS are usually single or multiple ulcers occurring recursively on the oral mucosa, round or oval in shape, clearly demarcated, with a gra
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Larsen, K., P. Holstein, and T. Deckert. "Limb salvage in diabetics with foot ulcers." Prosthetics and Orthotics International 13, no. 2 (1989): 100–103. http://dx.doi.org/10.3109/03093648909078221.

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The healing results in 491 ulcers in 272 diabetic patients are reported. Soft moulded insoles and shoe corrections were the main part of the therapy. There were 329 (67%) neuropathic, 87 (17%) traumatic, 44 (9%) ischaemic and 31 (6%) ulcers of other various pathogenesis. Thirty seven per cent of the ulcers were complicated with invasive infection. Within the period of observation of 18 months (3-39 months) healing was obtained in 79% of the patients (88% of the ulcers) and major amputation was carried out in 8% (4% of the ulcers). There were 21 major amputations, which in 18 cases was due to i
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Yammine, Kaissar, Marc Nahed, and Chahine Assi. "Metatarsal Osteotomies for Treating Neuropathic Diabetic Foot Ulcers: A Meta-analysis." Foot & Ankle Specialist 12, no. 6 (2018): 555–62. http://dx.doi.org/10.1177/1938640018819784.

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Diabetic foot ulcers (DFUs) are usually treated with conservative management based on debridement, topical agents, and nonsurgical off-loading; however, the recurrence rate following such standard care is reported to be high. In the case of recalcitrant or recurrent ulcers, a surgical off-loading technique such as the metatarsal osteotomy (MO) is indicated. Thus, the aim of this study is to conduct a meta-analysis evaluating the efficacy of MO in treating DFUs. Four relevant studies were identified, including 119 patients with 129 DFUs; all wounds were refractory to a previous conservative tre
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