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1

Meyle, J., C. Ottenlinger, and A. Klumpp. "Microtopography and Soft Tissue Architecture." Implant Dentistry 5, no. 2 (1996): 125. http://dx.doi.org/10.1097/00008505-199600520-00027.

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Meyle, J., C. Ottenlinger, and A. Klumpp. "Microtopography and Soft Tissue Architecture." Implant Dentistry 4, no. 2 (1996): 125. http://dx.doi.org/10.1097/00008505-199605000-00027.

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De Francesco, Maurizio, Elisabetta Ferrara, Francesco Inchingolo, et al. "Soft-Tissue Management Dental Implants with Digitally Customized Healing Abutments: A Pilot Study." Prosthesis 6, no. 3 (2024): 596–618. http://dx.doi.org/10.3390/prosthesis6030042.

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Background: This pilot study aimed to evaluate the effectiveness of digitally crafted customized healing abutments in stabilizing peri-implant soft tissues following tooth extraction and assess the preservation of peri-implant soft tissue architecture over 5 years. Material and Methods: Forty patients (age ≥ 25 years) were divided into test (n = 20) and control (n = 20) groups. The test group received dental implants with immediate loading after tooth extraction, along with customized healing abutments fabricated using CAD/CAM technology. The control group received dental implants with immedia
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Carotenuto, Felicia, Sara Politi, Arsalan Ul Haq, et al. "From Soft to Hard Biomimetic Materials: Tuning Micro/Nano-Architecture of Scaffolds for Tissue Regeneration." Micromachines 13, no. 5 (2022): 780. http://dx.doi.org/10.3390/mi13050780.

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Failure of tissues and organs resulting from degenerative diseases or trauma has caused huge economic and health concerns around the world. Tissue engineering represents the only possibility to revert this scenario owing to its potential to regenerate or replace damaged tissues and organs. In a regeneration strategy, biomaterials play a key role promoting new tissue formation by providing adequate space for cell accommodation and appropriate biochemical and biophysical cues to support cell proliferation and differentiation. Among other physical cues, the architectural features of the biomateri
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Karp, Jeffrey M., Paul D. Dalton, and Molly S. Shoichet. "Scaffolds for Tissue Engineering." MRS Bulletin 28, no. 4 (2003): 301–6. http://dx.doi.org/10.1557/mrs2003.85.

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AbstractDevices for tissue engineering comprise scaffolds with the appropriate chemistry and architecture to promote cell infiltration and colonization. The scaffold is designed with biology in mind, and thus the architecture and chemistry differ according to tissue type. In this review, we focus on scaffolds for two tissue types—bone and nervous tissue—and describe different approaches used to create them. The appropriate scaffold for a hard tissue such as bone has a high degree of interconnected macroporosity and allows the rapid invasion of cells while maintaining a rigid structure. Several
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Manicone, Paolo Francesco, Luca Raffaelli, Marjan Ghassemian, and Antonio D'Addona. "Soft and Hard Tissue Management in Implant Therapy—Part II: Prosthetic Concepts." International Journal of Biomaterials 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/356817.

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The ongoing pursuit of aesthetic excellence in the field of implant therapy has incorporated prosthetic concepts in the early treatment-planning phase, as well as the previously discussed surgical concepts. The literature has addressed these prosthetic and laboratory approaches required to enhance and perfect the soft and hard tissue management (SHTM). After surgically providing an acceptable hard tissue architecture and adequate timing of loading of the implant, the prosthetic phase is responsible for the soft tissue modeling, through correctly planned and executed procedures, which induce a
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Raza, Iwan G. A., Sarah J. B. Snelling, and Jolet Y. Mimpen. "Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review." Bone & Joint Research 13, no. 12 (2024): 703–15. https://doi.org/10.1302/2046-3758.1312.bjr-2024-0020.r1.

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AimsExtracellular matrix (ECM) is a critical determinant of tissue mechanobiology, yet remains poorly characterized in joint tissues beyond cartilage in osteoarthritis (OA). This review aimed to define the composition and architecture of non-cartilage soft joint tissue structural ECM in human OA, and to compare the changes observed in humans with those seen in animal models of the disease.MethodsA systematic search strategy, devised using relevant matrix, tissue, and disease nomenclature, was run through the MEDLINE, Embase, and Scopus databases. Demographic, clinical, and biological data were
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Yang, Bing, Xi Chen, Xiang Yun Liao, Mian Lun Zheng, and Zhi Yong Yuan. "FEM-Based Modeling and Deformation of Soft Tissue Accelerated by CUSPARSE and CUBLAS." Advanced Materials Research 671-674 (March 2013): 3200–3203. http://dx.doi.org/10.4028/www.scientific.net/amr.671-674.3200.

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Realistic modeling and deformation of soft tissue is one of the key technologies of virtual surgery simulation which is a challenging research field that stimulates the development of new clinical applications such as the virtual surgery simulator. In this paper we adopt the linear FEM (Finite Element Method) and sparse matrix compression stored in CSR (Compressed Sparse Row) format that enables fast modeling and deformation of soft tissue on GPU hardware with NVIDIA’s CUSPARSE (Compute Unified Device Architecture Sparse Matrix) and CUBLAS (Compute Unified Device Architecture Basic Linear Alge
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Pardo-Zamora, Guillermo, José Antonio Moreno-Rodríguez, and Antonio J. Ortiz-Ruíz. "Non-Incised Papilla Surgical Approach and Leukocyte Platelet-Rich Fibrin in Periodontal Reconstruction of Deep Intrabony Defects: A Case Series." International Journal of Environmental Research and Public Health 18, no. 5 (2021): 2465. http://dx.doi.org/10.3390/ijerph18052465.

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We present the preliminary results of the treatment of teeth with a deep, non-contained periodontal residual defect, vestibular bone dehiscence, and soft tissue recession, by combining an apical non-incised papilla surgical approach (NIPSA) to the defect and leukocyte platelet-rich fibrin (L-PRF) in the vestibular aspect. Four patients (upper left first premolar, upper left central incisor, upper right central incisor and upper right lateral incisor) have been treated. At one year of follow up, all cases showed a considerable reduction in the periodontal pocket depth, a gain in clinical attach
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Tupkari, Jagdish Vishnu, Tabita Joy Chettiakandy, Dimple Padawe, Keshav Kumar, Manisha Sardar, and Nandita Gupta. "Intraoral Soft Tissue Fibrosarcoma: A Case Report and Review." Journal of Contemporary Dentistry 4, no. 2 (2014): 118–23. http://dx.doi.org/10.5005/jp-journals-10031-1080.

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ABSTRACT Adult fibrosarcoma (FS), defined by the World Health Organization as ‘malignant neoplasm composed of fibroblasts with variable collagen production and, in classical cases, a ‘herringbone’ architecture’, is a very rare soft tissue sarcoma. The earlier literature revealed that the adult fibrosarcoma was the most commonly occurring lesion, however the incidence of which has declined dramatically over the past several decades. This is due to evolution in the classification of soft tissue tumors, recognition of its subtypes and increased understanding of the many other mesenchymal and nonm
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Berghage, Robert D., Royal D. Heins, Meriam Karlsson, John Erwin, and William Carlson. "Pinching Technique Influences Lateral Shoot Development in Poinsettia." Journal of the American Society for Horticultural Science 114, no. 6 (1989): 909–14. http://dx.doi.org/10.21273/jashs.114.6.909.

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Abstract Lateral shoot growth and plant morphology of poinsettia (Euphorbia pulcherrima Willd.) were influenced by the pinching technique used for apical meristem removal. Plants were pinched in one of four ways: 1) soft (removal of the apical meristem plus stem and leaf tissue associated with leaves ≤2 cm long); 2) medium (removal of the apical meristem plus stem and leaf tissue associated with leaves up to 7 cm long); 3) hard (removal of the apical meristem plus stem and leaf tissue associated with all immature leaves); and 4) leaf removal (LR; soft pinch as defined above plus removal of all
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Baume, Alex, Nick Coleman, and Philip Boughton. "Methods for Achieving Soft Tissue Scaffold Sterility." Journal of Biomimetics, Biomaterials and Tissue Engineering 4 (December 2009): 59–69. http://dx.doi.org/10.4028/www.scientific.net/jbbte.4.59.

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The manufacturing process for in vitro tissue culture products and medical devices relies on a validated sterilization route for ensuring product sterility, safety and performance. Two key aspects that contribute toward final sterilization validation are (1) the reliable estimation of product bioburden and (2) the development of a proficient sterile packaging system. Bioabsorbable composite systems and architecture of tissue scaffolds can lead to numerous challenges for bioburden testing and packaging design. This study is concerned with the development of bioburden assessment methods and pack
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Louis, Fiona, Marie Piantino, Hao Liu, et al. "Bioprinted Vascularized Mature Adipose Tissue with Collagen Microfibers for Soft Tissue Regeneration." Cyborg and Bionic Systems 2021 (March 13, 2021): 1–15. http://dx.doi.org/10.34133/2021/1412542.

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The development of soft tissue regeneration has recently gained importance due to safety concerns about artificial breast implants. Current autologous fat graft implantations can result in up to 90% of volume loss in long-term outcomes due to their limited revascularization. Adipose tissue has a highly vascularized structure which enables its proper homeostasis as well as its endocrine function. Mature adipocytes surrounded by a dense vascular network are the specific features required for efficient regeneration of the adipose tissue to perform host anastomosis after its implantation. Recently
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14

Sabharwal, Sanjeev, Robert D. Harten, Chris Sabatino, Jean S. Yun, and Kevin Munjal. "Selective Soft Tissue Release Preserves Growth Plate Architecture During Limb Lengthening." Journal of Pediatric Orthopaedics 25, no. 5 (2005): 617–22. http://dx.doi.org/10.1097/01.bpo.0000161835.65032.8c.

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Dipali, Pandey, Samaddar Souvik, Karmakar Arindam, and Taraphdar Sreetama. "Customized healing abutment for enhancing the emergence profile: A case report." Journal of Orofacial Rehabilitation 3, no. 2 (2023): 45–49. https://doi.org/10.5281/zenodo.8247318.

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<strong>Abstract</strong> <strong>Introduction: </strong>The esthetics of dental implants is dependent on the soft tissue form and emergence profile. The use of healing abutments has a history of producing the best aesthetic results and guiding the soft tissue. <strong>Case description: </strong>Healing abutments direct soft tissue recovery in proper shape. The round cross shape of traditional healing abutments and the same gingival architecture they produce might not be ideal for creating an attractive restoration. Therefore, in order to generate the ideal gingival architecture, a customized
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Nesic, Dobrila, Birgit M. Schaefer, Yue Sun, Nikola Saulacic, and Irena Sailer. "3D Printing Approach in Dentistry: The Future for Personalized Oral Soft Tissue Regeneration." Journal of Clinical Medicine 9, no. 7 (2020): 2238. http://dx.doi.org/10.3390/jcm9072238.

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Three-dimensional (3D) printing technology allows the production of an individualized 3D object based on a material of choice, a specific computer-aided design and precise manufacturing. Developments in digital technology, smart biomaterials and advanced cell culturing, combined with 3D printing, provide promising grounds for patient-tailored treatments. In dentistry, the “digital workflow” comprising intraoral scanning for data acquisition, object design and 3D printing, is already in use for manufacturing of surgical guides, dental models and reconstructions. 3D printing, however, remains un
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Villa-Campos, Oswaldo, Isabella Neme Ribeiro dos Reis, João Batista César-Neto, and Giuseppe Alexandre Romito. "Management of an extensive soft tissue deficiency prior to immediate implant in the aesthetic zone: a 4-year follow-up." BMJ Case Reports 17, no. 6 (2024): e259271. http://dx.doi.org/10.1136/bcr-2023-259271.

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Soft tissue deficiency in a tooth extraction site in the aesthetic area is a common and challenging clinical situation. This case report demonstrates the successful treatment of extensive gingival recession and buccal bone dehiscence associated with a hopeless tooth. Initially, a connective tissue graft was used to cover the root and thicken the soft tissue. After 2 months, the tooth was extracted, an implant was immediately placed, and a temporary restoration was installed. After 3 months, the soft tissue exhibited a natural and harmonious architecture. A custom zirconia abutment and crown we
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Moghe, Prabhas V. "Soft-Tissue Analogue Design and Tissue Engineering of Liver." MRS Bulletin 21, no. 11 (1996): 52–54. http://dx.doi.org/10.1557/s0883769400031857.

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Tissue engineering involves the application of physical and life sciences to develop functional substitutes for dysfunctional organs or tissue structures. From an engineering standpoint, tissues contain two basic components—the cells that are organized into proper units, and the material surrounding the cells, called the extracellular matrix (ECM). A third, frequently overlooked feature essential to the maintenance of the activity of the engineered tissue is the three-dimensional architecture of the cell-matrix composite.A comprehensive review of the scope and impact of tissue engineering has
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Won, Chiyun. "A Novel Framework for Optimizing Peri-Implant Soft Tissue in Subcrestally Placed Implants in Single Molar Cases: Integrating Transitional and Subcrestal Zones for Biological Stability." Journal of Clinical Medicine 14, no. 7 (2025): 2435. https://doi.org/10.3390/jcm14072435.

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Background/Objectives: The peri-implant soft tissue seal is crucial for the long-term success of subcrestally placed implants (SPIs). However, conventional biologic width—now referred to as supracrestal tissue attachment (STA)—models, originally developed for natural teeth, fail to account for the three-dimensional nature of peri-implant soft tissue adaptation. This study introduces a novel framework integrating the concepts of the transitional zone (TZ) and subcrestal zone (SZ) to systematically optimize peri-implant soft tissue architecture. Methods: A mathematical model was developed to det
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Prokic, Aleksandra, Minja Milicic-Lazic, and Igor Djordjevic. "Soft tissue management at delayed implant loading in the aesthetic zone: A case report." Serbian Dental Journal 70, no. 4 (2023): 196–202. http://dx.doi.org/10.2298/sgs2304196p.

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Emergence profile of implant-supported crowns is defined by the characteristics of supracrestal connective tissue (SCT), located between the implant platform and cervical soft tissue margin. This paper reflects the soft tissue contour management of implant-supported screw-retained crowns and the transfer of emergence profile using an indirectly customized impression coping. A 27-year-old male was referred for endosseus implant placement (Straumann BLT 0 4.1 mm ? 12 mm) in a region of a maxillary right central and lateral incisor. Teeth were extracted due to a cystic formation in the mentioned
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Nikoloudaki, Georgia, Sarah Brooks, Alexander P. Peidl, Dylan Tinney, and Douglas W. Hamilton. "JNK Signaling as a Key Modulator of Soft Connective Tissue Physiology, Pathology, and Healing." International Journal of Molecular Sciences 21, no. 3 (2020): 1015. http://dx.doi.org/10.3390/ijms21031015.

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In healthy individuals, the healing of soft tissues such as skin after pathological insult or post injury follows a relatively predictable and defined series of cell and molecular processes to restore tissue architecture and function(s). Healing progresses through the phases of hemostasis, inflammation, proliferation, remodeling, and concomitant with re-epithelialization restores barrier function. Soft tissue healing is achieved through the spatiotemporal interplay of multiple different cell types including neutrophils, monocytes/macrophages, fibroblasts, endothelial cells/pericytes, and kerat
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Srivastava, Sumedha, Veena Kalburgi, Nilojjawala Banerjee, Bimmi Tripathi, Milan Jain, and Shivam Singh. "Biological Width around One- and Two-piece Implants: A Systematic Review." Journal of Head & Neck Physicians and Surgeons 12, no. 1 (2024): 28–37. http://dx.doi.org/10.4103/jhnps.jhnps_45_24.

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The concept of biological width (BW) around dental implants is crucial for the long-term success of implant placement. This systematic review aimed to investigate the differences in BW around one- and two-piece dental implants and to assess the impact of implant design on peri-implant soft tissues. To compare biological width around one-piece and two-piece implant in a population undergone implant treatment. A comprehensive search of MEDLINE (via PubMed), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, Web of Science, CINAHL, PsycINFO, and Google Scholar was conducted
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Doxtader, Erika E., Sydney C. Butts, James W. Holsapple, and Christine E. Fuller. "Aggressive Pediatric Meningioma with Soft Tissue and Lymph Node Metastases: A Case Report." Pediatric and Developmental Pathology 12, no. 3 (2009): 244–48. http://dx.doi.org/10.2350/08-07-0501.1.

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Metastatic meningioma is extremely rare, occurring in an estimated 0.1% of cases. We report a case of pediatric meningioma metastatic to cervical soft tissue and lymph nodes. An 8-year-old boy presented with headaches, dizziness, and involuntary eye flickering. Magnetic resonance imaging (MRI) revealed a 7.5-cm parasagittal, dural-based mass with venous sinus encasement. Therapeutic embolization was followed by bilateral craniotomy, achieving subtotal resection. Histopathologic examination revealed an atypical meningioma with regions of hypercellularity, small cell morphology, sheeting archite
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Hawkins, Will C., Ryan M. Thiele, John P. Vardiman, and Philip M. Gallagher. "Effects of Instrument Assisted Soft Tissue Mobilization on Biceps Femoris Muscle Architecture." Medicine & Science in Sports & Exercise 50, no. 5S (2018): 352–53. http://dx.doi.org/10.1249/01.mss.0000536242.90290.41.

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Censi, Rachele, Virna Vavassori, Andrea Enrico Borgonovo, and Dino Re. "Esthetic Rehabilitation of a Severely Compromised Anterior Area: Combined Periodontal and Restorative Approach." Case Reports in Dentistry 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/658790.

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The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the execution of a coronally advanced flap for the treatment of multiple recession defects. Once complete healing
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Samad, Abduljaleel, Jodal Ahmed, Hundren M. Ali, Omed Shihab, Ahmed Haider, and Dainius Karpavicius. "Extraction Socket Seal Technique for Socket Preservation after Tooth Extraction: An Innovative Approach." Erbil Dental Journal 7, no. 1 (2024): 101–10. http://dx.doi.org/10.15218/edj.2024.12.

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Background and objectives: Tooth extraction triggers the loss of surrounding alveolar soft tissue and bone. Numerous socket preservation techniques have been used by clinical surgeons; the issue with all existing techniques is the loss of soft tissue anatomy, resulting in a flat soft tissue architecture. Our study introduces an innovative ridge preservation technique that addresses this problem; it involved using an anatomically shaped composite resin lid that acts as a graft sealant and an approach for maintaining the soft tissue cervical profile. Material and Methods: The Extraction Socket S
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Neetu, Vanapalli, Brindha S., and C. Shashikala. "Evaluation of the Role of Imprint Cytology and Frozen Section in Soft Tissue Lesions with Histopathological Correlation." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 359–65. https://doi.org/10.5281/zenodo.12554350.

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<strong>Introduction:</strong>&nbsp;Frozen section and imprint cytology are important intraoperative diagnostic procedures. Performance of frozen section is useful in determining the type of neoplasm, degree of malignancy and the adequacy of surgical margins. Imprint cytology has also been shown to be quite reliable in diagnosis of various soft tissue tumours. The tissue architecture seen in frozen section is close to the sections made in histopathology while imprint cytology provides a better cellular detail of tissue. Both the procedures show high degree of accuracy, in this study we have pl
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Ayadi, Lobna, and Abdelmajid Khabir. "Pediatric Angiosarcoma of Soft Tissue: A Rare Clinicopathologic Entity." Archives of Pathology & Laboratory Medicine 134, no. 3 (2010): 481–85. http://dx.doi.org/10.5858/134.3.481.

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Abstract Angiosarcomas are rare tumors that predominantly affect adults and elderly patients. Although angiosarcomas are well described in a variety of clinical settings, they have been poorly studied in children and little is known about their biology, natural history, or optimal treatment. Childhood angiosarcomas are exceedingly rare. The head and neck region and mediastinum seem to be the preferred locations. Most tumors are high-grade tumors. Vasoformative architecture is not always obvious on light microscopy requiring the benefit of immunohistochemical study. The differential diagnosis i
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Lazić, Vojkan, Ana Todorović, Igor Djordjević, Nataša Milošević, Danica Popović, and Ana Miletić. "Contouring the Emergence Profile of Peri-implant Soft Tissue by Provisionals on Implants – Case Report." Stomatoloski glasnik Srbije 62, no. 4 (2015): 196–201. http://dx.doi.org/10.1515/sdj-2015-0020.

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Summary Aesthetic outcome of implant therapy involves the appropriate architecture of peri-implant soft tissue and interdental papilla. The dynamic compression technique of soft tissue is mentioned in contemporary literature as one of the methods for achieving optimal emergence profile. The aim of this case report was to present soft tissue prosthetic modeling with temporary crowns on implants for obtaining an emergence profile of final restoration. A 25-year-old female patient with missing left maxillary central incisor was referred to the Department of Oral Surgery School of Dental Medicine
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BRESCOVITT, Ronaldo Antonio, Geninho THOMÉ, Ana Claúdia Moreira MELO, and Ricarda Duarte da SILVA. "Soft tissue behavior around dental implants placed in fresh extraction sockets and immediately restored in esthetic area: a preliminary short-term evaluation." Revista de Odontologia da UNESP 46, no. 4 (2017): 196–202. http://dx.doi.org/10.1590/1807-2577.21216.

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Abstract Objective To assess the behavior of the peri-implant soft margin after immediate implant placement with immediate function, by (1) direct clinical measurements of peri-implant soft margin height and thickness, (2) measurements of peri-implant soft margin height on photographs and (3) the perception of dental professionals regarding the results considering esthetic parameters. Material and method The study included 8 patients with central or lateral incisors indicated to be extracted. Direct measurements of peri-implant soft margin height and thickness were done immediately before extr
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Chella Krishnan, Karthickeyan, Santhosh Mukundan, Jeyashree Alagarsamy, et al. "Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse." PLOS Pathogens 12, no. 7 (2016): e1005732. http://dx.doi.org/10.1371/journal.ppat.1005732.

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Yin, Zi, Junxin Lin, Ruojin Yan, et al. "Atlas of Musculoskeletal Stem Cells with the Soft and Hard Tissue Differentiation Architecture." Advanced Science 7, no. 23 (2020): 2000938. http://dx.doi.org/10.1002/advs.202000938.

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Surowka, Artur D., A. Gianoncelli, G. Birarda, et al. "Soft X-ray induced radiation damage in thin freeze-dried brain samples studied by FTIR microscopy." Journal of Synchrotron Radiation 27, no. 5 (2020): 1218–26. http://dx.doi.org/10.1107/s1600577520010103.

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In order to push the spatial resolution limits to the nanoscale, synchrotron-based soft X-ray microscopy (XRM) experiments require higher radiation doses to be delivered to materials. Nevertheless, the associated radiation damage impacts on the integrity of delicate biological samples. Herein, the extent of soft X-ray radiation damage in popular thin freeze-dried brain tissue samples mounted onto Si3N4 membranes, as highlighted by Fourier transform infrared microscopy (FTIR), is reported. The freeze-dried tissue samples were found to be affected by general degradation of the vibrational archit
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Spyridon Maragkos and Giampietro Bertasi. "The use of Dermacell on a leg skin tear (ST)." GSC Advanced Research and Reviews 12, no. 3 (2022): 174–77. http://dx.doi.org/10.30574/gscarr.2022.12.3.0240.

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Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as extracellular matrix. Dermacell preserves 3D architecture and provides the necessary scaffolding to allow for cellular penetration and revascularization of the hADM into the patient.
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Spyridon, Maragkos, and Bertasi Giampietro. "The use of Dermacell on a leg skin tear (ST)." GSC Advanced Research and Reviews 12, no. 3 (2022): 174–77. https://doi.org/10.5281/zenodo.7179803.

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Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as extracellular matrix. Dermacell preserves 3D architecture and provides the necessary scaffolding to allow for cellular penetration and revascularization of the hADM into the patient.
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Khatami, Amir H., Mohammed Al-Ajmi, and Alejandro Kleinman. "Preservation of the Gingival Architecture With the Scalloped Implant Design: A Clinical Report." Journal of Oral Implantology 32, no. 4 (2006): 167–70. http://dx.doi.org/10.1563/798.1.

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Abstract Replacing the missing maxillary anterior teeth with dental implants and maintaining the soft tissue structure and alveolar profile is an esthetic challenge for the restorative dentist. This clinical report describes the immediate provisional placement and prosthetic rehabilitation of 2 missing maxillary central incisors with scalloped dental implants.
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Raheem, Ansheed A., Pearlin Hameed, Ruban Whenish, et al. "A Review on Development of Bio-Inspired Implants Using 3D Printing." Biomimetics 6, no. 4 (2021): 65. http://dx.doi.org/10.3390/biomimetics6040065.

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Biomimetics is an emerging field of science that adapts the working principles from nature to fine-tune the engineering design aspects to mimic biological structure and functions. The application mainly focuses on the development of medical implants for hard and soft tissue replacements. Additive manufacturing or 3D printing is an established processing norm with a superior resolution and control over process parameters than conventional methods and has allowed the incessant amalgamation of biomimetics into material manufacturing, thereby improving the adaptation of biomaterials and implants i
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38

Neumann, Erica E., Sean Doherty, James Bena, and Ahmet Erdemir. "Role of multi-layer tissue composition of musculoskeletal extremities for prediction of in vivo surface indentation response and layer deformations." PLOS ONE 18, no. 4 (2023): e0284721. http://dx.doi.org/10.1371/journal.pone.0284721.

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Emergent mechanics of musculoskeletal extremities (surface indentation stiffness and tissue deformation characteristics) depend on the underlying composition and mechanics of each soft tissue layer (i.e. skin, fat, and muscle). Limited experimental studies have been performed to explore the layer specific relationships that contribute to the surface indentation response. The goal of this study was to examine through statistical modeling how the soft tissue architecture contributed to the aggregate mechanical surface response across 8 different sites of the upper and lower extremities. A public
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39

Jorge, Eduardo Barragán Morales. "Role of Surgical Debridement in Wound Management." International Journal Of Medical Science And Clinical Research Studies 02, no. 11 (2022): 1238–40. https://doi.org/10.5281/zenodo.7309931.

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A wound is a disturbance of the skin&#39;s and soft tissue architecture&#39;s normal structure and function. Prior to further wound treatment, wounds with devitalized tissue, contamination, or leftover suture material benefit from debridement. Wound base preparation allows for the orderly healing and regeneration of injured tissue and may improve the performance of specialist wound care products and sophisticated biologic tissue replacements. There are now many approaches for treating individuals with Dupuytren&#39;s contracture; each case must be carefully selected to provide the most benefit
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Liu, Sijia, Yingjie Wang, Zhennan Li, Miao Jin, Lei Ren, and Chunbao Liu. "A fluid-driven soft robotic fish inspired by fish muscle architecture." Bioinspiration & Biomimetics 17, no. 2 (2022): 026009. http://dx.doi.org/10.1088/1748-3190/ac4afb.

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Abstract Artificial fish-like robots developed to date often focus on the external morphology of fish and have rarely addressed the contribution of the structure and morphology of biological muscle. However, biological studies have proven that fish utilize the contraction of muscle fibers to drive the protective flexible connective tissue to swim. This paper introduces a pneumatic silicone structure prototype inspired by the red muscle system of fish and applies it to the fish-like robot named Flexi-Tuna. The key innovation is to make the fluid-driven units simulate the red muscle fiber bundle
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41

Betini, Niteesha, Alana M. Munger, Douglas Rottmann, Andrew Haims, José Costa, and Dieter M. Lindskog. "Rare Presentation of Rosai-Dorfman Disease in Soft Tissue: Diagnostic Findings and Surgical Treatment." Case Reports in Surgery 2022 (March 30, 2022): 1–6. http://dx.doi.org/10.1155/2022/8440836.

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Introduction and Importance. Rosai-Dorfman disease (RDD) is a rare, benign type II histiocytosis characterized by the infiltration of S100+ histiocytes and emperipolesis. The disease may present in the lymph nodes (nodal RDD), in extranodal sites, or in both nodal and extranodal sites. Among those patients who present exclusively in extranodal sites, only a minority of cases present in the soft tissue. Case Presentation. An 18-year-old female presented to orthopedic oncology clinic with a chief complaint of a mass located in her lower back. The patient underwent excision of the lumbosacral mas
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R, Priavadhana, Meenakshisundaram K, Rajeswari T, and Kunnumbrath A. "Demographic and histopathologic study of soft tissue lesions in a tertiary care hospital in South India." Journal of Medical and Scientific Research 11, no. 3 (2023): 245–49. http://dx.doi.org/10.17727/jmsr.2023/11-45.

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The term soft tissue tumors (STT) encompass a wide range of tumors arising from the mesenchymal tissues. In this study, we have retrospectively analysed the various STTs occurring in the Department of Pathology and included all cases with a confirmed histopathological diagnosis of soft tissue lesions received during the study period of January 2018 – December 2019. These cases were further analysed for the site of the lesion, number of lesions, age and gender of the patients and the results tabulated. A total of 207 cases of soft tissue tumors with confirmed histopathological diagnosis were in
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43

Liguori, Anna, Alessandro De Vita, Giulia Rossi, et al. "A Modular Composite Device of Poly(Ethylene Oxide)/Poly(Butylene Terephthalate) (PEOT/PBT) Nanofibers and Gelatin as a Dual Drug Delivery System for Local Therapy of Soft Tissue Tumors." International Journal of Molecular Sciences 23, no. 6 (2022): 3239. http://dx.doi.org/10.3390/ijms23063239.

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In the clinical management of solid tumors, the possibility to successfully couple the regeneration of injured tissues with the elimination of residual tumor cells left after surgery could open doors to new therapeutic strategies. In this work, we present a composite hydrogel–electrospun nanofiber scaffold, showing a modular architecture for the delivery of two pharmaceutics with distinct release profiles, that is potentially suitable for local therapy and post-surgical treatment of solid soft tumors. The composite was obtained by coupling gelatin hydrogels to poly(ethylene oxide)/poly(butylen
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Martonosi, Ágnes Rita, Márió Mikóczi, Diana Molnár, László Szabó, and Zsuzsanna Zsófia Szalai. "Toxic shock syndrome in childhood – focusing on necrotising fasciitis." Bőrgyógyászati és Venerológiai Szemle 99, no. 5 (2023): 396–401. http://dx.doi.org/10.7188/bvsz.2023.99.5.10.

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Toxic Shock Syndrome (TSS) is an acute, toxin-mediated, severe illness with fever, hypotension, multi-organ failure, diffuse rash (diffuse macular erythroderma) and desquamation. Necrotizing fasciitis (NF) is a rapidly progressive soft tissue infection associated with fulminant tissue destruction, severe systemic toxicity and a high rate of mortality. It frequently is a diagnostic challenge because the initial symptoms are aspecific and superficial tissues may appear intact. Antibiotic therapy and early surgical intervention form the basis of appropriate treatment.
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Garcia-Torres, Francisco, Carlos A. Jurado, Silvia Rojas-Rueda, Clint Conner, Ali Abulkasim Mohamed, and Francisco X. Azpiazu-Flores. "Immediate Implant Therapy with Full-Digital Workflow to Replace a Central Incisor." Dentistry Journal 13, no. 2 (2025): 73. https://doi.org/10.3390/dj13020073.

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Background: Replacing a maxillary central incisor and immediately placing an implant represents a clinical challenge. Methods: This case report demonstrates a full digital workflow to achieve a predictable implant placement and esthetically pleasing restoration for a 35-year-old male patient who suffered a horizontal root fracture after a sports accident. The patient’s treatment included digital implant planning, minimally traumatic tooth extraction, computer-guided implant placement, soft tissue augmentation, and a provisional restoration to contour the augmented gingival tissues. The process
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Chen, Huanhuan, Guangying Song, Tianmin Xu, et al. "Biomaterial Scaffolds for Periodontal Tissue Engineering." Journal of Functional Biomaterials 15, no. 8 (2024): 233. http://dx.doi.org/10.3390/jfb15080233.

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Advanced periodontitis poses a significant threat to oral health, causing extensive damage and loss of both hard and soft periodontal tissues. While traditional therapies such as scaling and root planing can effectively halt the disease’s progression, they often fail to fully restore the original architecture and function of periodontal tissues due to the limited capacity for spontaneous regeneration. To address this challenge, periodontal tissue engineering has emerged as a promising approach. This technology centers on the utilization of biomaterial scaffolds, which function as three-dimensi
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47

Peeples, Joshua K., Julie F. Jameson, Nisha M. Kotta, Jonathan M. Grasman, Whitney L. Stoppel, and Alina Zare. "Jointly Optimized Spatial Histogram UNET Architecture (JOSHUA) for Adipose Tissue Segmentation." BME Frontiers 2022 (June 25, 2022): 1–14. http://dx.doi.org/10.34133/2022/9854084.

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Objective. We aim to develop a machine learning algorithm to quantify adipose tissue deposition at surgical sites as a function of biomaterial implantation. Impact Statement. To our knowledge, this study is the first investigation to apply convolutional neural network (CNN) models to identify and segment adipose tissue in histological images from silk fibroin biomaterial implants. Introduction. When designing biomaterials for the treatment of various soft tissue injuries and diseases, one must consider the extent of adipose tissue deposition. In this work, we analyzed adipose tissue accumulati
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48

Rosano, Gabriele, Silvio Taschieri, and Massimo Del Fabbro. "Immediate Postextraction Implant Placement Using Plasma Rich in Growth Factors Technology in Maxillary Premolar Region: A New Strategy for Soft Tissue Management." Journal of Oral Implantology 39, no. 1 (2013): 98–102. http://dx.doi.org/10.1563/aaid-joi-d-11-00043.

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Achieving an excellent aesthetic outcome in postextraction dental implant placement in the anterior maxilla is a challenging procedure for clinicians. In fact, there is an increased risk for soft tissue recession at the facial aspect which may require supplementary connective tissue grafts to accomplish the final aesthetic result. The aim of this case report is to describe a regenerative technique using autologous plasma rich in growth factors fibrin plug for preservation of soft tissue architecture around an implant immediately placed into an extraction site in the anterior maxilla. Such a pr
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Bedolla, Diana E., Andrea Mantuano, Arissa Pickler, et al. "Effects of soft X-ray radiation damage on paraffin-embedded rat tissues supported on ultralene: a chemical perspective." Journal of Synchrotron Radiation 25, no. 3 (2018): 848–56. http://dx.doi.org/10.1107/s1600577518003235.

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Radiation damage is an important aspect to be considered when analysing biological samples with X-ray techniques as it can induce chemical and structural changes in the specimens. This work aims to provide new insights into the soft X-ray induced radiation damage of the complete sample, including not only the biological tissue itself but also the substrate and embedding medium, and the tissue fixation procedure. Sample preparation and handling involves an unavoidable interaction with the sample matrix and could play an important role in the radiation-damage mechanism. To understand the influen
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Bülow, Astrid, Benedikt Schäfer, and Justus P. Beier. "Three-Dimensional Bioprinting in Soft Tissue Engineering for Plastic and Reconstructive Surgery." Bioengineering 10, no. 10 (2023): 1232. http://dx.doi.org/10.3390/bioengineering10101232.

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Skeletal muscle tissue engineering (TE) and adipose tissue engineering have undergone significant progress in recent years. This review focuses on the key findings in these areas, particularly highlighting the integration of 3D bioprinting techniques to overcome challenges and enhance tissue regeneration. In skeletal muscle TE, 3D bioprinting enables the precise replication of muscle architecture. This addresses the need for the parallel alignment of cells and proper innervation. Satellite cells (SCs) and mesenchymal stem cells (MSCs) have been utilized, along with co-cultivation strategies fo
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