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Teses / dissertações sobre o tema "Chemist activity"

Autor: Grafiati

Publicado: 12 de outubro de 2024

Última modificação: 31 de julho de 2025

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1

Fournier, Etienne. "Intérêt de la prise en compte des variabilités de l’activité et de l’acceptabilité dans le cadre d’une conception centrée utilisateurs des situations de travail collaboratives Humain-Robot." Electronic Thesis or Diss., Université Grenoble Alpes, 2024. http://www.theses.fr/2024GRALH011.

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La Commission Européenne encourage l’utilisation de robots collaboratifs (cobots) pour assister l’humain dans son travail. Cependant, les cobots semblent avoir des difficultés à transformer favorablement les situations de travail lorsqu’ils ne prennent pas en compte les variabilités des situations. Cette thèse s’est donc donnée comme objectifs de caractériser les variabilités dans le cadre d’une l’implémentation cobotique et de guider une démarche de conception centrée sur les futurs utilisateurs en mobilisant les approches d’acceptabilité, d’acceptation et d’expérience utilisateur. Une analys

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2

Catti, Federica. "4,5-dihydropyrazoles : novel chemistry and biological activity." Thesis, St Andrews, 2007. http://hdl.handle.net/10023/351.

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3

Davidson, Nicola E. "Glucosinolates and isothiocyanates : chemistry and biological activity." Thesis, University of St Andrews, 1999. http://hdl.handle.net/10023/14230.

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The ability of glucosinolates to act as host recognition cues and oviposition stimulants for root flies has been previously established. To further investigate the interactions between pest and glucosinolate a number of simple and complex glucosinolates were synthesised and tested by contact chemoreception. A crude structure-activity relationship was identified whereby the stimulatory activity of the glucosinolate increased as the alkyl side chain was increased from propyl to pentyl, heptyl and nonyl. Comparison of the novel synthetic glucosinolate, naphthylmethyl glucosinolate, with glucobras

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4

Kulkarni, M. M. "Chemistry and biological activity of natural products." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1986. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3276.

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5

Li, Ju-Yun. "Quantitative structure-activity relationship studies in medicinal chemistry." Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1062596938.

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6

Pathirana, Navin Deepal. "Chemistry and biological activity of iron quinoneoximic complexes." Thesis, London Metropolitan University, 1990. http://repository.londonmet.ac.uk/2977/.

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The synthesis and structure of 1,2-quinone mono-oximes have been reviewed. The reaction of 3-hydroxyphenol, 3-hydroxy-2-aethylphenol, 3-hydroxy-5-methylphenol and N-acetyl-3-aminophenol with amyl nitrite/M(OEt) (M - Na or K) has been systematically examined. It has been found that the complex formed depends on the reaction temperature and phenol/M(OEt) ratio. Infra-red spectroscopic studies have shown that in the solid state 5-hydroxy-l,2-benzoquinone 2-oxime (hqoH,), 5-hydroxy-3-methyl-l,2-benzoquinone 2-oxime (3-MehqoH2), 5-hydroxy-6-methyl-l,2-benzoquinone 2-oxime (e-MehqoH,) and H-acetyl-5

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7

Cox, Kaleb Woodrow. "Synthesis and Biological Activity of Indolinones." Wright State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=wright1421165680.

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8

Nunes, R. J. "The chemistry and biological activity of cyclic imidobenzenesulphonyl derivatives." Thesis, University of Hertfordshire, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370823.

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9

Paige, Mikell Atkin. "Modular synthesis of Annonaceous acetogenins and their activity against H-116 human solid colon tumor cells." Full text, Acrobat Reader required, 2003. http://viva.lib.virginia.edu/etd/diss/ArtsSci/Chemistry/2003/Paige/Dissertation.pdf.

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10

Murphy, Veronica L. "Optical Activity of Achiral Molecules." Thesis, New York University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10192177.

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<p> Optical activity is typically first introduced to a prospective chemist in her sophomore year organic chemistry course. Here, she is taught that optical activity is a consequence of chirality, for example, <i> L-</i>tartaric acid has a specific rotation of +12° at the sodium <i> D-</i>line. However, this leaves said chemist with a wildly skewed and rather vague understanding of the concept of optical activity. There are two major problems with the current understanding of optical activity. The first is that both theory and experiment have shown that optical activity is, in fact, not a

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11

Fitzpatrick, Matthew F. "The interfacial chemistry and environmental degradation of adhesively bonded galvanised steel." Thesis, University of Surrey, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322539.

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12

Miller, Matthew Dean Holder Andrew J. "Applications of quantum chemistry to polymerization reactions and biological activity." Diss., UMK access, 2004.

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Thesis (Ph. D.)--Dept. of Chemistry and School of Pharmacy. University of Missouri--Kansas City, 2004.<br>"A dissertation in chemistry and pharmaceutical science." Advisor: Andrew J. Holder. Typescript. Vita. Description based on contents viewed Feb. 27, 2006; title from "catalog record" of the print edition. Includes bibliographical references (leaves 206-221). Online version of the print edition.

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13

Roberts, Glyn. "The influence of catalyst precursor chemistry on methanol synthesis activity." Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317194.

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14

Srivastava, Sanjay. "Structure-activity relationship studies in medicinal chemistry and drug design." Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1056054628.

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15

Ptchelintsev, Dmitri Stanislav. "Structure-activity relationship studies in chemoreception, toxicology and medicinal chemistry." Case Western Reserve University School of Graduate Studies / OhioLINK, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=case1060866168.

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16

Cavagnero, Silvia 1962. "Structure-activity studies of delta-selective opioid analogues." Thesis, The University of Arizona, 1990. http://hdl.handle.net/10150/278183.

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The two structurally different peptides DPDPE and Dermenkephalin show a similar remarkably high affinity and selectivity for the delta opioid receptor subtype. An effort has been made to gain some insight into the factors responsible for the recognition ability of these two molecules by synthesizing some DPDPE-Dermenkephalin peptide hybrids and some conformationally restricted Dermenkephalin analogues. The results of the binding and the in-vitro bioassays have been compared with those of the parent peptides. A general decrease in receptor affinity has been observed in the peptide hybrids while

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17

Ramsamy, Tanya A. "The regulation of hepatic lipase activity." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/29156.

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Human hepatic lipase (HL) is a 66-kDa glycoprotein that plays an important role in the metabolism of apoB-containing lipoproteins and high density lipoproteins (HDL). Both the lipid and apolipoprotein composition of lipoproteins have been shown to modulate HL activity. In this study, very low density lipoproteins (VLDL) were found to be the best lipoprotein substrates for HL followed by low density lipoproteins (LDL) and HDL. Only 1% of the fatty acids released from HDL3 by HL are derived from triglycerides (TG) whereas the remainder of fatty acids produced are from the lipolysis of diglycerid

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18

Rabindran, Ray 1964. "Inhibition of tau kinase activity by ATP." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47691.

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19

Moi, Giulia. "Chemistry and biological activity of Kigelia pinnata relevant to skin conditions." Thesis, King's College London (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.601502.

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20

Mathabathe, Kgadi Clarrie. "Manifestations of metacognitive activity in an upper undergraduate organic chemistry laboratory." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/60839.

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This study was carried out to investigate how metacognitive activity, particularly cognitive regulation, manifests in the collaborative planning of chemistry practical investigations by senior undergraduate students in a simulated industrial project. The participating students worked in home groups to evaluate three synthetic routes for a given compound, and decided on a preferred route while considering the criteria of cost, technical challenge, and environmental impact. This is consistent with the jigsaw learning technique. During the planning session, the students who were evaluating the sa

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21

Price, Craig Justin. "Structure-activity relationships in olefin polymerization catalysts." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1678.

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22

Escribano, Rivero Juan Ricardo. "Studies on natural Raman optical activity." Thesis, University of Glasgow, 1985. http://theses.gla.ac.uk/8690/.

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Optical activity associated with vibrations of chiral molecules can provide much stereochemical information. There are two techniques which observe vibrational optical activity (VOA), namely: infrared circular dichroism (IRCD) and vibrational Raman optical activity (VROA). The first, IRCD, is an extension of circular dichroism into the infrared and measures a difference in absorbance of incident left and right circularly polarized infrared radiation. VROA is concerned with a difference in the intensity of Raman scattering when the chiral system is illuminated with left and right circularly pol

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23

Wilson, Mark James. "Activity relationships for aromatic crown ethers." Thesis, University of Strathclyde, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249872.

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24

Poisot, Vazquez Martha Emilia [Verfasser]. "Studies to develop high activity MoS2 : crystallography, thermal analysis and catalytic activity / Martha Emilia Poisot Vazquez." Kiel : Universitätsbibliothek Kiel, 2008. http://d-nb.info/1019613386/34.

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25

Saran, Dayal. "Novel phosphotransferase ribozyme with ATPgammaS hydrolase activity." [Bloomington, Ind.] : Indiana University, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3215205.

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Thesis (Ph. D.)--Indiana University, Dept. of Chemistry, 2006.<br>Source: Dissertation Abstracts International, Volume: 67-04, Section: B, page: 1995. Adviser: Donald H. Burke. "Title from dissertation home page (viewed June 20, 2007)."

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26

Mukherjee, Herschel. "On the Biological Activity of the Natural Product (+)-Avrainvillamide." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467289.

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Nucleophosmin (NPM1) is a multifunctional phosphoprotein localized predominantly within the nucleoli of eukaryotic cells. Mutations within its C-terminal domain are frequently observed in patients with acute myeloid leukemia (AML), are thought to play a key role in the initiation and progression of the disease, and result in aberrant, cytoplasmic localization of the mutant protein. It has previously been demonstrated that the electrophilic antiproliferative natural product (+)-avrainvillamide binds to proteins, including nucleophosmin, by ¬S-alkylation of cysteine residues. In this thesis we r

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27

He, Qing 1973. "Understanding and improving the anticancer activity of cisplatin." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/44508.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2001.<br>Vita.<br>Includes bibliographical references.<br>The purpose of this thesis is to further our understanding of the mechanism of action of cis-diamminedichloroplatinum(II) (cisplatin), one of the most effective anticancer drugs. Since its serendipitous discovery in 1970, cisplatin has served to help cure testicular cancer and treat a variety of human malignancies. It is widely accepted that DNA is the cellular target for cisplatin. Prior to this work, several structures of duplex DNA modified by cisplatin reveal

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28

Moore, Madeleine Henrietta. "Structure-activity relationships in Werner clathrates." Doctoral thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/17038.

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Includes bibliographical references.<br>The synthesis and characterization of a series of inorganic coordination compounds which, upon crystallization, have the ability to include solvent or guest molecules spatially within the lattice are reported. The compounds have the following general formula: [NiX2B4] - where X is isothiocyanate or bromine and B is 4-ethylpyridine, 4-vinylpiridine or 3,5-dimethylpyridine; [NiX2B2]n - where X is isothiocyanate, B is 2-aminopyridine and n indicates it is a polymer; [NiX2AB2]2 - where X is isothiocyanate, B is 3-aminopyridine (two of these four ligands in t

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29

Caporali, Roberto. "Understanding the activity and the chemistry of Pd-based diesel oxidation catalysts." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669674.

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Several technologies offer a promising strategy for the exhaust after-treatment of diesel engines in which continuing to further thrift Pt/Pd alloy diesel oxidation catalysts (DOC) by increasing Pd content, the prospect of an essentially Pt-free DOC catalyst is very attractive because Pd is cheaper than Pt. However, to determine the viability of this approach a much better understanding of PdO/AI20 3 chemistry and reactivity is needed. Therefore, the aim of this work is (1) to improve the catalytic performance of the Pd based ?iesel oxidation catalyst by using different preparation method and

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30

Salem, M. A. A. "Electron transfer activity of some oxide catalysts." Thesis, Queen's University Belfast, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374993.

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31

Harries, C. M. "Antidepressant activity of N-desmethylclomipramine." Thesis, Cardiff University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370790.

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32

Gabrielli, William Fullard. "Structure activity relationship studies of ochratoxin A analogues." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53070.

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Thesis (MSc)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: Mycotoxins have assumed worldwide importance due to the ubiquitous occurrence of toxigenic fungi, their infestation of plant-based foods and feeds and the subsequent economical and health impact it because of their contamination of commercial products. Ochratoxin A (OA) is a nephrotoxic mycotoxin produced by isolates of Aspergillus ochraceus and Penicillium verrucosum and occurs frequently in nature. The major target for toxicity of OA in mammalian species is the kidneys and it has been the major cause of Danish Porcine N

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33

Mah, Wayne. "Single molecule study of RecA recombinase enzyme activity." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18743.

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Homologous recombination is an essential pathway in the repair of DNA damage during the DNA replication process. RecA protein promotes the central steps in homologous recombination, after coating single-stranded DNA (ssDNA), RecA carries out a pairing and strand exchange reaction involving homologous DNA. This research project aims to characterize RecA function in homologous recombination using single molecule tethered particle motion (TPM). Using TPM to observe RecA extension along DNA, the RecA extension rate on ssDNA was determined for the first time. The rate obtained for dsDNA was

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34

Hsu, Bryan Boen. "Investigation of microbicidal activity of surface-immobilized hydrophobic polycations." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/62728.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Hydrophobic polycations have been shown to completely kill bacterial, fungal, and viral pathogens, on-contact. Herein we describe advances with this technology on two fronts: (1) innovation of a polycationic-derivative that simplifies the labor-intensive covalent-immobilization procedure, and (2) elucidation of the current mechanistic understanding of this phenomenon. First, we developed and characterized a novel polycationic polyme

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35

Centani, Luyanda. "Structure activity and structure property relationships of antimalarial imidazopyridazines." Master's thesis, Faculty of Science, 2019. http://hdl.handle.net/11427/31315.

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Malaria is one of the most pressing human health issues. Despite being an ancient disease, it is estimated to have an annual death rate of 445 000 with out of 216 million malaria related cases in 2016. Malaria is most widespread in developing regions of the world. Forty percent of the world’s population is exposed to varying degrees of malaria. Malaria is caused by different species of the Plasmodium genus and the disease is vector-borne. The disease may be cured if diagnosed early. Most drugs that were once effective in the treatment of malaria have become ineffective due to the emergence of

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36

Briscoe, N. A. "Ultrastructure and catalytic activity of some complex oxides." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355717.

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37

Lau, S. "Cobalt(III) acetate - its structures and catalytic activity." Thesis, University of Hull, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233969.

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38

Wilson, Gary. "Vibrational Raman optical activity of peptides and proteins." Thesis, University of Glasgow, 1996. http://theses.gla.ac.uk/6144/.

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Vibrational Raman optical activity (ROA) which is the difference in the Raman scattering of left and right circularly polarised incident light, has recently emerged as a new and incisive probe of biomolecular structure. This thesis is based on new applications of ROA to some current biochemical problems. The first chapter is a brief explanation of the origin of chirality and the development of vibrational optical activity with special emphasis on ROA. Chapter 2 is a theoretical analysis of ROA and provides a fundamental explanation of the phenomenon. This involves a description as to how the R

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39

McDonald, Russell Walker. "Synthesis and anticancer activity of NDGA and analogues." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274867.

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40

Lear, Tim. "Structure/activity correlations in alumina supported palladium catalysts." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275617.

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41

Park, Seongsoon. "Enhancing hydrolase activity and selectivity by medium, substrate, and protein engineering." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=83088.

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Researchers use enzymes for enantio- and regioselective reactions because of their high selectivity and activity toward natural substrates. However, researchers sometimes need to modify the reaction system or the enzyme itself to get reliable selectivity and activity when they deal with unnatural substrates. To obtain researcher's need, one can change the solvent, modify the substrates, or alter the enzyme itself. These processes are called medium, substrate, and protein engineering, respectively.<br>This thesis deals with hydrolases, which are classified by EC 3. We applied the proper

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42

Torrie, Joan P. "Extracellular beta-D-mannanase activity from Trichoderma harzianum E58." Thesis, University of Ottawa (Canada), 1991. http://hdl.handle.net/10393/7732.

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In this work, 4 yeasts (Pichia wickerhammi, Candida wickerhammi, Pichia stipitis CBS5776, Pichia stipitis CBS5876), and 5 fungi (Theivalia spp., Thermoascus aurantiacus, Tyromyces palustris A, Aspergillus niger, Trichoderma harzianum), known to excrete enzymes capable of hydrolyzing polysaccharides found in association with $\beta$-D-mannans, were assessed for their ability to degrade $\beta$-D-mannans. The $\beta$-D-mannanase activity found in the culture filtrate of T. harzianum was selected for further study and a 'cellulase-free' $\beta$-D-mannanase isolated from culture filtrates of T. ha

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43

Auer, Erich Nicholaus. "Methods of blocking efflux pump activity in Escherichia coli." University of Dayton / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1524660216368043.

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44

Howes, Melanie-Jayne Rosemarie. "Chemistry and biological activity of plants with traditional uses relevant to Alzheimer's disease." Thesis, King's College London (University of London), 2001. https://kclpure.kcl.ac.uk/portal/en/theses/chemistry-and-biological-activity-of-plants-with-traditional-uses-relevant-to-alzheimers-disease(57cd4b39-dee2-445e-b6f8-74bb88d30437).html.

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45

Techatanawat, Isariya. "Chemistry and cytotoxic activity of some Thai medicinal plants used to treat cancer." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427990.

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46

Stoerzinger, Kelsey A. (Kelsey Ann). "Understanding the catalytic activity of oxides through their electronic structure and surface chemistry." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104113.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references.<br>The intermittent nature of renewable energy sources requires a clean, scalable means of converting and storing energy. Water electrolysis can sustainably achieve this goal by storing energy in the bonds of oxygen and hydrogen molecules. T

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47

Al-Salihi, Suhad Adnam Ahmed. "Unlocking the genetics and the chemistry behind the antimicrobial activity of Hypholoma species." Thesis, University of Bristol, 2018. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752777.

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48

Vignes, Maéva. "Development and activity of in vitro neuronal networks : learning organic chemistry through games." Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05T080/document.

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Ma thèse comporte deux grandes parties, la première en biophysique et la seconde en science de l’éducation. La première partie présente des travaux à la frontière entre neurobiologie et microfluidique. Le but de ces travaux est de pouvoir reconstruire et étudier des réseaux complexes de neurones in vitro avec une topologie de connections synaptiques bien contrôlées. Une série de micro-structures mécanique et/ou chimique ont été étudiées pour leur capacité à (i) positionner les corps cellulaires des neurones, (ii) orienter la pousse des neurites, et (iii) différencier les axones des dendrites.

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49

De, Nisi Assunta <1987&gt. "Novel insights into gold(I) chemistry: from anticancer activity to new synthetic methodologies." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8597/1/DNA%20PhDFull14mar18.pdf.

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The work herein presented, embraces various aspects of gold chemistry: the documentation of novel [alkynyl(triphenylphosphine)gold(I)] complexes carrying differently substituted propargylic amines and their pharmacological investigation on a series of cancer cell lines and the investigation of the dearomative cycloaddition reaction of indoles with electron-rich allenes catalysed by commercially available gold(I) complexes that show competence in performing the chemo-, regio- and diastereoselective formal [2+2]-cycloaddition between a wide range of substrates under mild conditions. It has als

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50

McFadyen, Iain James. "Structure-activity relationships of opioid ligands." Thesis, Loughborough University, 1999. https://dspace.lboro.ac.uk/2134/33189.

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There are three different types of opioid receptor, namely mu, delta and kappa. Morphine and related clinically useful analgesics exert their actions through the mu opioid receptor. Such compounds represent a huge structural diversity, including both peptides and alkaloids. Nevertheless, there exists a common pharmacophore comprising two critical features, namely an amine nitrogen and an aromatic ring, usually with a hydroxyl substituent; the spatial relationship between them is also vital.

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