Добірка наукової літератури з теми "Innate IELs"
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Статті в журналах з теми "Innate IELs":
Qiu, Yuan, Aimin Pu, Hong Zheng, Minqiang Liu, Weigang Chen, Wensheng Wang, Weidong Xiao, and Hua Yang. "TLR2-Dependent Signaling for IL-15 Production Is Essential for the Homeostasis of Intestinal Intraepithelial Lymphocytes." Mediators of Inflammation 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/4281865.
Hummel, Jonas F., Patrice Zeis, Karolina Ebert, Jonas Fixemer, Philip Konrad, Christian Schachtrup, Sebastian J. Arnold, Dominic Grün, and Yakup Tanriver. "Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1− T-bet+ intraepithelial lymphocyte precursors." Mucosal Immunology 13, no. 2 (November 11, 2019): 257–70. http://dx.doi.org/10.1038/s41385-019-0220-y.
Kooy-Winkelaar, Yvonne M. C., Dagmar Bouwer, George M. C. Janssen, Allan Thompson, Martijn H. Brugman, Frederike Schmitz, Arnoud H. de Ru, et al. "CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes." Proceedings of the National Academy of Sciences 114, no. 6 (January 3, 2017): E980—E989. http://dx.doi.org/10.1073/pnas.1620036114.
Jiang, Wei, Xiaqiong Wang, Benhua Zeng, Lei Liu, Aubry Tardivel, Hong Wei, Jiahuai Han, et al. "Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes." Journal of Experimental Medicine 210, no. 11 (September 23, 2013): 2465–76. http://dx.doi.org/10.1084/jem.20122490.
Losurdo, Giuseppe, Domenico Piscitelli, Federica Pezzuto, Francesco Fortarezza, Claudia Covelli, Antonella Marra, Andrea Iannone, et al. "T Helper Lymphocyte and Mast Cell Immunohistochemical Pattern in Nonceliac Gluten Sensitivity." Gastroenterology Research and Practice 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/5023680.
Kisielow, Jan, Luigi Tortola, Jacqueline Weber, Klaus Karjalainen та Manfred Kopf. "Evidence for the divergence of innate and adaptive T-cell precursors before commitment to the αβ and γδ lineages". Blood 118, № 25 (15 грудня 2011): 6591–600. http://dx.doi.org/10.1182/blood-2011-05-352732.
Billiet, Lore, Glenn Goetgeluk, Sarah Bonte, Stijn De Munter, Laurenz De Cock, Melissa Pille, Joline Ingels, et al. "Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a– CD95+ CD28– CCR7– Developmental Stage." International Journal of Molecular Sciences 21, no. 22 (November 20, 2020): 8785. http://dx.doi.org/10.3390/ijms21228785.
Clarizio, A. V., H. J. Galipeau, J. Jury, L. Rondeau, J. Godbout, L. Williams, B. Anderson, and E. Verdu. "A19 NOVEL HLA-DQ2 TRANSGENIC MICE DEVELOP GLUTEN-IMMUNOPATHOLOGY FOLLOWING GLUTEN SENSITIZATION." Journal of the Canadian Association of Gastroenterology 3, Supplement_1 (February 2020): 22–23. http://dx.doi.org/10.1093/jcag/gwz047.018.
Bhinder, Ganive, Martin Stahl, Ho Pan Sham, Shauna M. Crowley, Vijay Morampudi, Udit Dalwadi, Caixia Ma, Kevan Jacobson, and Bruce A. Vallance. "Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses." Infection and Immunity 82, no. 9 (June 23, 2014): 3753–63. http://dx.doi.org/10.1128/iai.02045-14.
Hosomi, Shuhei, Joep Grootjans, Markus Tschurtschenthaler, Niklas Krupka, Juan D. Matute, Magdalena B. Flak, Eduardo Martinez-Naves, et al. "Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation." Journal of Experimental Medicine 214, no. 10 (July 26, 2017): 2985–97. http://dx.doi.org/10.1084/jem.20162041.
Дисертації з теми "Innate IELs":
Hariss, Fatima. "Etude du rôle des Lymphocytes Intraépithéliaux innés dans la réponse immune protectrice contre Cryptosporidium parvum." Thesis, Université de Lille (2018-2021), 2021. http://www.theses.fr/2021LILUS047.
Intraepithelial lymphocytes (IEL) reside between intestinal epithelial cells and thus are the first immune cells to contact intestinal pathogens. In addition to respond rapidly to infection, they regulate intestinal homeostasis and maintain the epithelial barrier. This wide range of functions is achieved by distinct subsets of T and innate lymphocytes. Innate IEL which share many features with NK/ILC1 cells have been identified recently. These cells dominate the gut epithelium at birth and when the adaptive immunity is compromised. Their role in the immune response against intestinal pathogens remains however poorly studied.During my PhD thesis, I have investigated the role of innate IEL subsets in Crysptosporidium infection. Crysptosporidium is a common parasite that infects the gut epithelium. The infection is self-limiting in immunocompetent individuals, but it can be severe in immunocompromised individuals and children in whom innate IEL dominate.To study the specific role of innate IEL, we have developed an in vitro model that consist to co-culture mice 3D intestinal organoids infected with C parvum with innate IELs from RAG2-/- mice. Thanks to this original model, we demonstrated that innate IELs control parasite proliferation. We further showed that although innate IEL secrete IFN-ƴ in response to C parvum infection, the IFN-ƴ secretion was not sufficient to inhibit parasite proliferation. The protective effect of innate IELs was in fact mediated by a cytotoxic, granzyme-dependent mechanism. Moreover, transcriptomic analysis revealed that infected epithelial cells down regulated serpinb9b, a granzyme inhibitor, and thus may be more sensitive to cytotoxic attack
Pietz, Grzegorz. "Innate immunity of human intestinal epithelium in childhood celiac disease : influences from celiac disease associated bacteria and dietary oats." Doctoral thesis, Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-140691.
Doctoral thesis
Книги з теми "Innate IELs":
Linden, Mary Anne, and Barbara D. Bateman. Better IEPs: How to Develop Legally Correct and Educationally Useful Programs. 3rd ed. Longmont, CO, USA: Sopris West, 1998.